Guide to the Human Genome
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Search of human proteins with 4885543

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885543 pyruvate dehydrogenase E1 alpha 2 [Homo sapiens]
         (388 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885543 pyruvate dehydrogenase E1 alpha 2 [Homo sapiens]           789   0.0  
gi|4505685 pyruvate dehydrogenase E1 alpha 1 precursor [Homo sap...   682   0.0  
gi|11386135 branched chain keto acid dehydrogenase E1, alpha pol...   115   5e-26
gi|38788380 dehydrogenase E1 and transketolase domain containing...    46   7e-05
gi|51873036 oxoglutarate (alpha-ketoglutarate) dehydrogenase (li...    36   0.052
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]           33   0.57 
gi|21362052 carbohydrate (N-acetylglucosamine 6-O) sulfotransfer...    32   1.3  
gi|205277463 transketolase isoform 1 [Homo sapiens]                    32   1.3  
gi|4507521 transketolase isoform 1 [Homo sapiens]                      32   1.3  
gi|157388965 schlafen family member 11 [Homo sapiens]                  30   2.8  
gi|157388963 schlafen family member 11 [Homo sapiens]                  30   2.8  
gi|157388961 schlafen family member 11 [Homo sapiens]                  30   2.8  
gi|157388959 schlafen family member 11 [Homo sapiens]                  30   2.8  
gi|157388957 schlafen family member 11 [Homo sapiens]                  30   2.8  
gi|93141226 X-prolyl aminopeptidase 2, membrane-bound [Homo sapi...    29   6.3  
gi|50593110 5' nucleotidase, cytosolic IB isoform 1 [Homo sapiens]     29   6.3  
gi|50593108 5' nucleotidase, cytosolic IB isoform 2 [Homo sapiens]     29   6.3  
gi|133778974 transketolase-like 2 [Homo sapiens]                       29   8.3  

>gi|4885543 pyruvate dehydrogenase E1 alpha 2 [Homo sapiens]
          Length = 388

 Score =  789 bits (2038), Expect = 0.0
 Identities = 388/388 (100%), Positives = 388/388 (100%)

Query: 1   MLAAFISRVLRRVAQKSARRVLVASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGL 60
           MLAAFISRVLRRVAQKSARRVLVASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGL
Sbjct: 1   MLAAFISRVLRRVAQKSARRVLVASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGL 60

Query: 61  KYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHG 120
           KYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHG
Sbjct: 61  KYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHG 120

Query: 121 VCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACK 180
           VCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACK
Sbjct: 121 VCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACK 180

Query: 181 YKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTSTERAAASPDY 240
           YKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTSTERAAASPDY
Sbjct: 181 YKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTSTERAAASPDY 240

Query: 241 YKRGNFIPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSDPGVSYR 300
           YKRGNFIPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSDPGVSYR
Sbjct: 241 YKRGNFIPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSDPGVSYR 300

Query: 301 TREEIQEVRSKRDPIIILQDRMVNSKLATVEELKEIGAEVRKEIDDAAQFATTDPEPHLE 360
           TREEIQEVRSKRDPIIILQDRMVNSKLATVEELKEIGAEVRKEIDDAAQFATTDPEPHLE
Sbjct: 301 TREEIQEVRSKRDPIIILQDRMVNSKLATVEELKEIGAEVRKEIDDAAQFATTDPEPHLE 360

Query: 361 ELGHHIYSSDSSFEVRGANPWIKFKSVS 388
           ELGHHIYSSDSSFEVRGANPWIKFKSVS
Sbjct: 361 ELGHHIYSSDSSFEVRGANPWIKFKSVS 388


>gi|4505685 pyruvate dehydrogenase E1 alpha 1 precursor [Homo
           sapiens]
          Length = 390

 Score =  682 bits (1760), Expect = 0.0
 Identities = 333/388 (85%), Positives = 356/388 (91%), Gaps = 1/388 (0%)

Query: 1   MLAAFISRVLRRVAQKSARRVLVASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGL 60
           MLAA +SRVL   +QK A RVLVASRN +NDATFEIKKCDL+ LEEGPPVTTVLTR +GL
Sbjct: 4   MLAA-VSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGL 62

Query: 61  KYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHG 120
           KYYRMM TVRRMELKADQLYKQK IRGFCHLCDGQEACCVGLEAGINP+DH+IT+YRAHG
Sbjct: 63  KYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHG 122

Query: 121 VCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACK 180
             +TRGLSVR ILAELTGR+GGCAKGKGGSMHMY KNFYGGNGIVGAQ PLGAGIALACK
Sbjct: 123 FTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACK 182

Query: 181 YKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTSTERAAASPDY 240
           Y G DE+CLTLYGDGAANQGQI EA+NMAALWKLPC+FICENN YGMGTS ERAAAS DY
Sbjct: 183 YNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDY 242

Query: 241 YKRGNFIPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSDPGVSYR 300
           YKRG+FIPGL+VDGMD+LCVREAT+FAA YCRSGKGPILMELQTYRYHGHSMSDPGVSYR
Sbjct: 243 YKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYR 302

Query: 301 TREEIQEVRSKRDPIIILQDRMVNSKLATVEELKEIGAEVRKEIDDAAQFATTDPEPHLE 360
           TREEIQEVRSK DPI++L+DRMVNS LA+VEELKEI  EVRKEI+DAAQFAT DPEP LE
Sbjct: 303 TREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLE 362

Query: 361 ELGHHIYSSDSSFEVRGANPWIKFKSVS 388
           ELG+HIYSSD  FEVRGAN WIKFKSVS
Sbjct: 363 ELGYHIYSSDPPFEVRGANQWIKFKSVS 390


>gi|11386135 branched chain keto acid dehydrogenase E1, alpha
           polypeptide [Homo sapiens]
          Length = 445

 Score =  115 bits (289), Expect = 5e-26
 Identities = 89/318 (27%), Positives = 141/318 (44%), Gaps = 5/318 (1%)

Query: 54  LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
           L + + LK Y+ M  +  M+    +  +Q  I  F     G+E   VG  A ++ +D V 
Sbjct: 97  LPKEKVLKLYKSMTLLNTMDRILYESQRQGRI-SFYMTNYGEEGTHVGSAAALDNTDLVF 155

Query: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
             YR  GV   R   +   +A+  G      KG+   +H   K  +F   +  +  Q P 
Sbjct: 156 GQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQ 215

Query: 172 GAGIALACKYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGTST 231
             G A A K    + + +  +G+GAA++G     FN AA  + P +F C NN Y + T T
Sbjct: 216 AVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPT 275

Query: 232 ERAAASPDYYKRGNF--IPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHG 289
                      RG    I  ++VDG DV  V  ATK A     +   P L+E  TYR   
Sbjct: 276 SEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGH 335

Query: 290 HSMSDPGVSYRTREEIQEVRSKRDPIIILQDRMVNSKLATVEELKEIGAEVRKEIDDAAQ 349
           HS SD   +YR+ +E+     +  PI  L+  +++      E+ K    + R+++ +A +
Sbjct: 336 HSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAWRKQSRRKVMEAFE 395

Query: 350 FATTDPEPHLEELGHHIY 367
            A   P+P+   L   +Y
Sbjct: 396 QAERKPKPNPNLLFSDVY 413


>gi|38788380 dehydrogenase E1 and transketolase domain containing 1
           [Homo sapiens]
          Length = 919

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 46/189 (24%), Positives = 80/189 (42%), Gaps = 18/189 (9%)

Query: 183 GNDEICLTLYGDGA-ANQGQIAEAFNMAALWKLPC---VFICENNLYGMGTSTERAAASP 238
           G+  ICL ++GD +   QG + E F ++ L        V +  NN  G  T  ER  +S 
Sbjct: 322 GDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSL 381

Query: 239 DYYKRGNFIPG--LKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSDPG 296
                G  +    + V+G     V  AT+ A  Y R  +  ++++L  YR  GH+  D  
Sbjct: 382 YCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEP 441

Query: 297 VSYRTREEIQEVRSKRDPIIILQDRMVNSKLATVEELKEIGAEVRKEIDDAAQFATTDPE 356
             Y      + +R+++       + ++   L T EE+ EI +    +++D          
Sbjct: 442 F-YTNPIMYKIIRARKSIPDTYAEHLIAGGLMTQEEVSEIKSSYYAKLND---------- 490

Query: 357 PHLEELGHH 365
            HL  + H+
Sbjct: 491 -HLNNMAHY 498


>gi|51873036 oxoglutarate (alpha-ketoglutarate) dehydrogenase
           (lipoamide) isoform 1 precursor [Homo sapiens]
          Length = 1023

 Score = 36.2 bits (82), Expect = 0.052
 Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 8/120 (6%)

Query: 182 KGNDEICLTLYGDGA-ANQGQIAEAFNMAALWKLPC---VFICENNLYGMGTSTERAAAS 237
           +G   + + L+GD A A QG + E F+++ L        V +  NN  G  T    A +S
Sbjct: 399 EGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSS 458

Query: 238 P---DYYKRGNFIPGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYHGHSMSD 294
           P   D  +  N  P   V+  D   V    K AA +  +    ++++L  YR +GH+  D
Sbjct: 459 PYPTDVARVVN-APIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMD 517


>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
          Length = 747

 Score = 32.7 bits (73), Expect = 0.57
 Identities = 33/105 (31%), Positives = 44/105 (41%), Gaps = 19/105 (18%)

Query: 76  ADQLYKQKFIRGFCHLCDGQEACC----------VGLEAGINPSDHVITSYRAHGVCYTR 125
           A+Q+     + GF   C  ++ C           +G+  G+      I S   HG  YT 
Sbjct: 506 AEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTF 565

Query: 126 GLS---VRSILA----ELTGRRG-GCAK-GKGGSMHMYTKNFYGG 161
            L     RSIL     EL G+    CAK G   S+  +TK FYGG
Sbjct: 566 SLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGG 610


>gi|21362052 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase
           5 [Homo sapiens]
          Length = 411

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 40/187 (21%), Positives = 67/187 (35%), Gaps = 37/187 (19%)

Query: 203 AEAFNMAALWKLPCVFICENNLYG------------MGTSTERAAASP---DYYKRGNFI 247
           A   +MA    +  +F+C+ +++                +T RA  SP     + RG   
Sbjct: 107 AATLHMAVRDLMRSIFLCDMDVFDAYMPQSRNLSAFFNWATSRALCSPPACSAFPRGTIS 166

Query: 248 PGLKVDGMDVLCVREATKFAANYCRSGKGPILMELQTYRYH---------------GHSM 292
              K D    LC R+    A   CRS    +L E++ +                   H +
Sbjct: 167 ---KQDVCKTLCTRQPFSLAREACRSYSHVVLKEVRFFNLQVLYPLLSDPALNLRIVHLV 223

Query: 293 SDPGVSYRTREEIQEVRSKRDPIIILQDRMVNSKLATVEELKEIGAEVRKEIDDAAQFAT 352
            DP    R+RE    + ++ + I++      N K    +    +  EV +     A+ AT
Sbjct: 224 RDPRAVLRSREAAGPILARDNGIVL----GTNGKWVEADPHLRLIREVCRSHVRIAEAAT 279

Query: 353 TDPEPHL 359
             P P L
Sbjct: 280 LKPPPFL 286


>gi|205277463 transketolase isoform 1 [Homo sapiens]
          Length = 623

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 8/85 (9%)

Query: 167 AQGPLGAGIALAC--KYKGN--DEICLTLY---GDGAANQGQIAEAFNMAALWKLP-CVF 218
           A G LG G+  AC   Y G   D+    +Y   GDG  ++G + EA   A+++KL   V 
Sbjct: 121 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA 180

Query: 219 ICENNLYGMGTSTERAAASPDYYKR 243
           I + N  G             Y KR
Sbjct: 181 ILDINRLGQSDPAPLQHQMDIYQKR 205


>gi|4507521 transketolase isoform 1 [Homo sapiens]
          Length = 623

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 8/85 (9%)

Query: 167 AQGPLGAGIALAC--KYKGN--DEICLTLY---GDGAANQGQIAEAFNMAALWKLP-CVF 218
           A G LG G+  AC   Y G   D+    +Y   GDG  ++G + EA   A+++KL   V 
Sbjct: 121 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA 180

Query: 219 ICENNLYGMGTSTERAAASPDYYKR 243
           I + N  G             Y KR
Sbjct: 181 ILDINRLGQSDPAPLQHQMDIYQKR 205


>gi|157388965 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 36/142 (25%), Positives = 60/142 (42%), Gaps = 9/142 (6%)

Query: 6   ISRVLRRVAQKSARRVLVASRNSSNDATFEIKK---CDLYLLEEG--PPVTTVLTR--AE 58
           +  ++ +  Q   R +L+ SR+ + D   + K    CD  L+ +   P + T+L    AE
Sbjct: 423 LEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAE 482

Query: 59  GLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRA 118
           G  Y        + +L     Y  K       LC   E+    LEA ++P D+   SY  
Sbjct: 483 GQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYP-ASYSL 541

Query: 119 HGVCYTRGLSVRSILAELTGRR 140
            G  +   L ++S++  L G R
Sbjct: 542 AGTQHMEAL-LQSLVIVLLGFR 562


>gi|157388963 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 36/142 (25%), Positives = 60/142 (42%), Gaps = 9/142 (6%)

Query: 6   ISRVLRRVAQKSARRVLVASRNSSNDATFEIKK---CDLYLLEEG--PPVTTVLTR--AE 58
           +  ++ +  Q   R +L+ SR+ + D   + K    CD  L+ +   P + T+L    AE
Sbjct: 423 LEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAE 482

Query: 59  GLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRA 118
           G  Y        + +L     Y  K       LC   E+    LEA ++P D+   SY  
Sbjct: 483 GQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYP-ASYSL 541

Query: 119 HGVCYTRGLSVRSILAELTGRR 140
            G  +   L ++S++  L G R
Sbjct: 542 AGTQHMEAL-LQSLVIVLLGFR 562


>gi|157388961 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 36/142 (25%), Positives = 60/142 (42%), Gaps = 9/142 (6%)

Query: 6   ISRVLRRVAQKSARRVLVASRNSSNDATFEIKK---CDLYLLEEG--PPVTTVLTR--AE 58
           +  ++ +  Q   R +L+ SR+ + D   + K    CD  L+ +   P + T+L    AE
Sbjct: 423 LEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAE 482

Query: 59  GLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRA 118
           G  Y        + +L     Y  K       LC   E+    LEA ++P D+   SY  
Sbjct: 483 GQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYP-ASYSL 541

Query: 119 HGVCYTRGLSVRSILAELTGRR 140
            G  +   L ++S++  L G R
Sbjct: 542 AGTQHMEAL-LQSLVIVLLGFR 562


>gi|157388959 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 36/142 (25%), Positives = 60/142 (42%), Gaps = 9/142 (6%)

Query: 6   ISRVLRRVAQKSARRVLVASRNSSNDATFEIKK---CDLYLLEEG--PPVTTVLTR--AE 58
           +  ++ +  Q   R +L+ SR+ + D   + K    CD  L+ +   P + T+L    AE
Sbjct: 423 LEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAE 482

Query: 59  GLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRA 118
           G  Y        + +L     Y  K       LC   E+    LEA ++P D+   SY  
Sbjct: 483 GQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYP-ASYSL 541

Query: 119 HGVCYTRGLSVRSILAELTGRR 140
            G  +   L ++S++  L G R
Sbjct: 542 AGTQHMEAL-LQSLVIVLLGFR 562


>gi|157388957 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 36/142 (25%), Positives = 60/142 (42%), Gaps = 9/142 (6%)

Query: 6   ISRVLRRVAQKSARRVLVASRNSSNDATFEIKK---CDLYLLEEG--PPVTTVLTR--AE 58
           +  ++ +  Q   R +L+ SR+ + D   + K    CD  L+ +   P + T+L    AE
Sbjct: 423 LEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAE 482

Query: 59  GLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRA 118
           G  Y        + +L     Y  K       LC   E+    LEA ++P D+   SY  
Sbjct: 483 GQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYP-ASYSL 541

Query: 119 HGVCYTRGLSVRSILAELTGRR 140
            G  +   L ++S++  L G R
Sbjct: 542 AGTQHMEAL-LQSLVIVLLGFR 562


>gi|93141226 X-prolyl aminopeptidase 2, membrane-bound [Homo
           sapiens]
          Length = 674

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 30/98 (30%), Positives = 41/98 (41%), Gaps = 31/98 (31%)

Query: 196 AANQGQIAEAFNMAALWKLPC-----------VFIC---------ENNL---YGMGTSTE 232
           AA  G++ EAF   ALW                F+C          NN+    GM TS E
Sbjct: 496 AATSGRMVEAFARRALWDAGLNYGHGTGHGIGNFLCVHEWPVGFQSNNIAMAKGMFTSIE 555

Query: 233 RAAASPDYYKRGNFIPGLKVDGMDVLCVREATKFAANY 270
                P YYK G F  G++++ +  L V   TK+  +Y
Sbjct: 556 -----PGYYKDGEF--GIRLEDV-ALVVEAKTKYPGSY 585


>gi|50593110 5' nucleotidase, cytosolic IB isoform 1 [Homo sapiens]
          Length = 610

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 7/63 (11%)

Query: 323 VNSKLATVEELKEIGAEVRK-------EIDDAAQFATTDPEPHLEELGHHIYSSDSSFEV 375
           + + L T       GA V K       EID+A   A     P L ++  HI+  D  F +
Sbjct: 531 IRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKSPILVKIRPHIFFDDHMFHI 590

Query: 376 RGA 378
            GA
Sbjct: 591 EGA 593


>gi|50593108 5' nucleotidase, cytosolic IB isoform 2 [Homo sapiens]
          Length = 550

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 7/63 (11%)

Query: 323 VNSKLATVEELKEIGAEVRK-------EIDDAAQFATTDPEPHLEELGHHIYSSDSSFEV 375
           + + L T       GA V K       EID+A   A     P L ++  HI+  D  F +
Sbjct: 471 IRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKSPILVKIRPHIFFDDHMFHI 530

Query: 376 RGA 378
            GA
Sbjct: 531 EGA 533


>gi|133778974 transketolase-like 2 [Homo sapiens]
          Length = 626

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 7/55 (12%)

Query: 167 AQGPLGAGIALAC------KYKGNDEI-CLTLYGDGAANQGQIAEAFNMAALWKL 214
           A G LG G+  AC      KY          L GDG +++G + EAF  A+ + L
Sbjct: 122 ATGSLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNL 176


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,706,686
Number of Sequences: 37866
Number of extensions: 663746
Number of successful extensions: 1463
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1458
Number of HSP's gapped (non-prelim): 23
length of query: 388
length of database: 18,247,518
effective HSP length: 104
effective length of query: 284
effective length of database: 14,309,454
effective search space: 4063884936
effective search space used: 4063884936
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press