Guide to the Human Genome
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Name: PDHA1 Sequence: fasta or formatted (390aa) NCBI GI: 4505685
Description:

pyruvate dehydrogenase E1 alpha 1 precursor

Referenced in:

TCA Cycle

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.5         37           3
 C cysteine            3.1         12           2
 D aspartate           4.9         19           1
 E glutamate           7.2         28           2
 F phenylalanine       3.3         13           1
 G glycine             9.2         36           2
 H histidine           2.1          8           1
 I isoleucine          5.1         20           2
 K lysine              5.9         23           2
 L leucine             7.9         31           2
 M methionine          3.6         14           2
 N asparagine          3.3         13           2
 P proline             3.8         15           2
 Q glutamine           3.1         12           1
 R arginine            7.2         28           2
 S serine              5.4         21           2
 T threonine           4.4         17           2
 V valine              5.9         23           1
 W tryptophan          0.5          2           1
 Y tyrosine            4.6         18           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   pyruvate dehydrogenase E1 alpha 1 precursor 
PDHA2                 0.855   pyruvate dehydrogenase E1 alpha 2 
BCKDHA                0.124   branched chain keto acid dehydrogenase E1, alpha pol...
DHTKD1                0.021   dehydrogenase E1 and transketolase domain containing...
OGDH                  0.016   oxoglutarate (alpha-ketoglutarate) dehydrogenase (li...
TKT                   0.013   transketolase isoform 1 
TKT                   0.013   transketolase isoform 1 
FBXL16                0.009   F-box and leucine-rich repeat protein 16 
TKTL2                 0.007   transketolase-like 2 
RPGRIP1L              0.005   RPGRIP1-like isoform b 
SCP2                  0.005   sterol carrier protein 2 isoform 1 proprotein 
PEG10                 0.005   paternally expressed 10 isoform RF1 
PEG10                 0.005   paternally expressed 10 isoform RF1/2 
TKT                   0.005   transketolase isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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