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Search of human proteins with 48527952
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48527952 golgi associated, gamma adaptin ear containing, ARF
binding protein 1 isoform 2 [Homo sapiens]
(552 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48527952 golgi associated, gamma adaptin ear containing, ARF ... 1103 0.0
gi|9558729 golgi associated, gamma adaptin ear containing, ARF b... 781 0.0
gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens] 475 e-134
gi|20336267 ADP-ribosylation factor binding protein 3 isoform lo... 382 e-106
gi|14719400 ADP-ribosylation factor binding protein 3 isoform sh... 303 2e-82
gi|239758145 PREDICTED: similar to ADP-ribosylation factor bindi... 144 2e-34
gi|48527954 golgi associated, gamma adaptin ear containing, ARF ... 144 2e-34
gi|131888135 target of myb1-like 2 isoform 3 [Homo sapiens] 94 4e-19
gi|71773010 adaptor-related protein complex 1, gamma 1 subunit i... 92 1e-18
gi|71772942 adaptor-related protein complex 1, gamma 1 subunit i... 92 1e-18
gi|209180457 target of myb1 isoform 2 [Homo sapiens] 91 2e-18
gi|4885637 target of myb1 isoform 1 [Homo sapiens] 91 2e-18
gi|209180448 target of myb1 isoform 3 [Homo sapiens] 82 1e-15
gi|191252812 target of myb1-like 1 [Homo sapiens] 80 5e-15
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 69 1e-11
gi|209180450 target of myb1 isoform 4 [Homo sapiens] 68 2e-11
gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [H... 66 9e-11
gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens] 64 3e-10
gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens] 61 3e-09
gi|222418647 mucin 7, secreted precursor [Homo sapiens] 54 5e-07
gi|222418649 mucin 7, secreted precursor [Homo sapiens] 54 5e-07
gi|222418645 mucin 7, secreted precursor [Homo sapiens] 54 5e-07
gi|118918413 MICAL C-terminal like [Homo sapiens] 43 9e-04
gi|54860079 nadrin isoform 1 [Homo sapiens] 42 0.001
gi|76563940 synuclein alpha interacting protein [Homo sapiens] 42 0.001
gi|54860105 nadrin isoform 2 [Homo sapiens] 42 0.002
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 40 0.004
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 40 0.007
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 40 0.007
gi|157785645 SPEG complex locus [Homo sapiens] 40 0.007
>gi|48527952 golgi associated, gamma adaptin ear containing, ARF
binding protein 1 isoform 2 [Homo sapiens]
Length = 552
Score = 1103 bits (2852), Expect = 0.0
Identities = 552/552 (100%), Positives = 552/552 (100%)
Query: 1 MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60
MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE
Sbjct: 1 MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60
Query: 61 WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY 120
WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY
Sbjct: 61 WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY 120
Query: 121 SWTVGLPEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLAR 180
SWTVGLPEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLAR
Sbjct: 121 SWTVGLPEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLAR 180
Query: 181 LLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGA 240
LLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGA
Sbjct: 181 LLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGA 240
Query: 241 AAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALGLSDPTPPSGPSLDGTGWNSFQS 300
AAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALGLSDPTPPSGPSLDGTGWNSFQS
Sbjct: 241 AAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALGLSDPTPPSGPSLDGTGWNSFQS 300
Query: 301 SDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQ 360
SDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQ
Sbjct: 301 SDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQ 360
Query: 361 QPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESI 420
QPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESI
Sbjct: 361 QPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESI 420
Query: 421 KPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKV 480
KPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKV
Sbjct: 421 KPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKV 480
Query: 481 MKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDV 540
MKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDV
Sbjct: 481 MKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDV 540
Query: 541 DQFPPPETWGSL 552
DQFPPPETWGSL
Sbjct: 541 DQFPPPETWGSL 552
>gi|9558729 golgi associated, gamma adaptin ear containing, ARF
binding protein 1 isoform 1 [Homo sapiens]
Length = 639
Score = 781 bits (2018), Expect = 0.0
Identities = 432/641 (67%), Positives = 471/641 (73%), Gaps = 91/641 (14%)
Query: 1 MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60
MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE
Sbjct: 1 MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60
Query: 61 WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY 120
WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY
Sbjct: 61 WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY 120
Query: 121 SWT------VGLPEEVKIAEAYQMLKKQGIVKSD------PKLPDDTTFP---------- 158
SWT V + E ++ + ++K + D P P + F
Sbjct: 121 SWTVGLPEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLAR 180
Query: 159 -LPPPRP----------KNVIFEDEEKSKMLARLLKS----------------SHPEDLR 191
L P K ++ ED+++ + +++ + + SH +
Sbjct: 181 LLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGA 240
Query: 192 AANK---LIKEMVQEDQKRM--------------EKISKRVNAIEEVNNNVKLLTEMVMS 234
AA L+KE+ Q ++ E +++ + A + + + L ++V
Sbjct: 241 AAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRG 300
Query: 235 HS-QGGAAAGSSEDLMKELY----------------------QRCERMRPTLFRLASDTE 271
G A AGS L ++ +P+ S +
Sbjct: 301 EEVNGDATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSAS--VSLLD 358
Query: 272 DNDEALGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASS 331
D +LGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASS
Sbjct: 359 DELMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASS 418
Query: 332 GLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHT 391
GLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHT
Sbjct: 419 GLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHT 478
Query: 392 VSPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRS 451
VSPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRS
Sbjct: 479 VSPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRS 538
Query: 452 DVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLL 511
DVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLL
Sbjct: 539 DVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLL 598
Query: 512 ANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL 552
ANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL
Sbjct: 599 ANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL 639
>gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens]
Length = 613
Score = 475 bits (1222), Expect = e-134
Identities = 278/586 (47%), Positives = 371/586 (63%), Gaps = 55/586 (9%)
Query: 9 TLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQALT 68
+LE +N+AT+P E DW++I FCEQ+N D GP A LLAHKIQSPQE EA+ ALT
Sbjct: 25 SLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYALT 84
Query: 69 VLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPE 128
VLE CM CG++FH EV KFRFLNELIKV+SPKYLGS + KVK +++E+L+SWTV PE
Sbjct: 85 VLEMCMNHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPE 144
Query: 129 EVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFE-DEEKSKMLARLLKSSHP 187
++KI +AYQMLKKQGI+K DPKLP D P P P PK+ IF+ DEEKSK+L RLLKS+HP
Sbjct: 145 DIKIRDAYQMLKKQGIIKQDPKLPVDKILPPPSPWPKSSIFDADEEKSKLLTRLLKSNHP 204
Query: 188 EDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSSED 247
EDL+AAN+LIK +V+E+Q++ EK+SKRV+A+EEV ++VK+L EM+ + + G A E
Sbjct: 205 EDLQAANRLIKNLVKEEQEKSEKVSKRVSAVEEVRSHVKVLQEMLSMYRRPGQAPPDQEA 264
Query: 248 LMKELYQRCERMRPTLFRLASDTEDNDEALG--------LSDPTPPSGPSLDG--TGWNS 297
L + +Y+RCE++RPTLFRLASDT D+D+AL L+ ++G T N
Sbjct: 265 L-QVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQVMEGRVTFGNR 323
Query: 298 FQSSDATEP-------PAPALAQAPSME---SRPPAQ--TSLP-------ASSGLDDLDL 338
SS P PA + P ++ PAQ T +P A+ G+ D +
Sbjct: 324 VTSSLGDIPVSRVFQNPAGCMKTCPLIDLEVDNGPAQMGTVVPSLLHQDLAALGISDAPV 383
Query: 339 LGKTLLQQSL-----PPESQQVRWEKQQPTPRLTLRDL---------QNKSSSCSSP--- 381
G Q P S Q P+ L DL N S S P
Sbjct: 384 TGMVSGQNCCEEKRNPSSSTLPGGGVQNPSADRNLLDLLSAQPAPCPLNYVSQKSVPKEV 443
Query: 382 ---SSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRI 438
+ S+ P P P Q P LA + VPLES+KPS++ P+ VYD++GFRI
Sbjct: 444 PPGTKSSPGWSWEAGPLAPSPSSQNTP----LAQVFVPLESVKPSSLPPLIVYDRNGFRI 499
Query: 439 LFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNP 498
L HF++ PG +V V++++M+STAPQP+ +I+FQ AVPK M+VKLQP S ++LPAF+P
Sbjct: 500 LLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSP 559
Query: 499 IVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFP 544
++ P+ I+Q+LLL NP KE +RLRYKLTF G Q ++E+G+V FP
Sbjct: 560 LMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFP 605
>gi|20336267 ADP-ribosylation factor binding protein 3 isoform long
[Homo sapiens]
Length = 723
Score = 382 bits (980), Expect = e-106
Identities = 182/274 (66%), Positives = 232/274 (84%), Gaps = 2/274 (0%)
Query: 6 EPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQ 65
E E+LE+ +N+ATNP N++ DW I GFC+Q+N++ EGP +A RLLAHKIQSPQEWEA+Q
Sbjct: 5 EGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQ 64
Query: 66 ALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVG 125
ALTVLE CMK+CG+RFH+EVGKFRFLNELIKVVSPKYLG R SEKVK K++ELLYSWT+
Sbjct: 65 ALTVLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMA 124
Query: 126 LPEEVKIAEAYQMLKKQGIVKSDPKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKS 184
LPEE KI +AY MLK+QGIV+SDP +P D T P PPPRPKN +F+DEEKSK+LA+LLKS
Sbjct: 125 LPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKS 184
Query: 185 SHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGS 244
+P+DL+ ANKLIK MV+ED+ R++K++KR++ +EEVNNNV+LL+EM++ +SQ ++ G
Sbjct: 185 KNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSDGD 244
Query: 245 SEDLMKELYQRCERMRPTLFRLASDTEDNDEALG 278
E LMKEL+ +CE R TLF+LAS+TEDND +LG
Sbjct: 245 RE-LMKELFDQCENKRRTLFKLASETEDNDNSLG 277
Score = 226 bits (577), Expect = 3e-59
Identities = 143/274 (52%), Positives = 170/274 (62%), Gaps = 24/274 (8%)
Query: 280 SDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLP-ASSGLDDLDL 338
S P P +G SL TG APALA P +E P L +S L LD
Sbjct: 473 SVPAPSAGSSLFSTG------------VAPALA--PKVEPAVPGHHGLALGNSALHHLDA 518
Query: 339 LGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPR 398
L + L + + + PT R L S+ SP S SP P+
Sbjct: 519 LDQLLEEAKVTSGLVKPTTSPLIPTTT-PARPLLPFSTGPGSPLFQPLSFQSQGSP--PK 575
Query: 399 PPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVV 458
P ELSLASI VPLESIKPS+ LPVT YD++GFRILFHFA++ PGR DVLVVVV
Sbjct: 576 GP------ELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVV 629
Query: 459 SMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEK 518
SML+TAP P+++IV Q+AVPK MKVKLQPPSGTEL F+PI P+AITQV+LLANP KEK
Sbjct: 630 SMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEK 689
Query: 519 VRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL 552
VRLRYKLTF +G+Q E+G+VDQFPP E WG+L
Sbjct: 690 VRLRYKLTFALGEQLSTEVGEVDQFPPVEQWGNL 723
>gi|14719400 ADP-ribosylation factor binding protein 3 isoform short
[Homo sapiens]
Length = 690
Score = 303 bits (777), Expect = 2e-82
Identities = 153/274 (55%), Positives = 200/274 (72%), Gaps = 35/274 (12%)
Query: 6 EPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQ 65
E E+LE+ +N+ATNP N++ DW I GFC+Q+N++ EGP +A RLLAHKIQSPQEWEA+Q
Sbjct: 5 EGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQ 64
Query: 66 ALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVG 125
ALT YLG R SEKVK K++ELLYSWT+
Sbjct: 65 ALT---------------------------------YLGDRVSEKVKTKVIELLYSWTMA 91
Query: 126 LPEEVKIAEAYQMLKKQGIVKSDPKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKS 184
LPEE KI +AY MLK+QGIV+SDP +P D T P PPPRPKN +F+DEEKSK+LA+LLKS
Sbjct: 92 LPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKS 151
Query: 185 SHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGS 244
+P+DL+ ANKLIK MV+ED+ R++K++KR++ +EEVNNNV+LL+EM++ +SQ ++ G
Sbjct: 152 KNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDSSDGD 211
Query: 245 SEDLMKELYQRCERMRPTLFRLASDTEDNDEALG 278
E LMKEL+ +CE R TLF+LAS+TEDND +LG
Sbjct: 212 RE-LMKELFDQCENKRRTLFKLASETEDNDNSLG 244
Score = 226 bits (577), Expect = 3e-59
Identities = 143/274 (52%), Positives = 170/274 (62%), Gaps = 24/274 (8%)
Query: 280 SDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLP-ASSGLDDLDL 338
S P P +G SL TG APALA P +E P L +S L LD
Sbjct: 440 SVPAPSAGSSLFSTG------------VAPALA--PKVEPAVPGHHGLALGNSALHHLDA 485
Query: 339 LGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPR 398
L + L + + + PT R L S+ SP S SP P+
Sbjct: 486 LDQLLEEAKVTSGLVKPTTSPLIPTTT-PARPLLPFSTGPGSPLFQPLSFQSQGSP--PK 542
Query: 399 PPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVV 458
P ELSLASI VPLESIKPS+ LPVT YD++GFRILFHFA++ PGR DVLVVVV
Sbjct: 543 GP------ELSLASIHVPLESIKPSSALPVTAYDKNGFRILFHFAKECPPGRPDVLVVVV 596
Query: 459 SMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEK 518
SML+TAP P+++IV Q+AVPK MKVKLQPPSGTEL F+PI P+AITQV+LLANP KEK
Sbjct: 597 SMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPLKEK 656
Query: 519 VRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL 552
VRLRYKLTF +G+Q E+G+VDQFPP E WG+L
Sbjct: 657 VRLRYKLTFALGEQLSTEVGEVDQFPPVEQWGNL 690
>gi|239758145 PREDICTED: similar to ADP-ribosylation factor binding
protein 2 [Homo sapiens]
Length = 134
Score = 144 bits (364), Expect = 2e-34
Identities = 66/118 (55%), Positives = 94/118 (79%)
Query: 427 PVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQ 486
P+ VYD++GFRIL HF++ PG +V V++++M+STAPQP+ +I+FQ AVPK M+VKLQ
Sbjct: 9 PLIVYDRNGFRILLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQ 68
Query: 487 PPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFP 544
P S ++LPAF+P++ P+ I+Q+LLL NP KE +RLRYKLTF G Q ++E+G+V FP
Sbjct: 69 PASSSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFP 126
>gi|48527954 golgi associated, gamma adaptin ear containing, ARF
binding protein 1 isoform 3 [Homo sapiens]
Length = 89
Score = 144 bits (364), Expect = 2e-34
Identities = 69/69 (100%), Positives = 69/69 (100%)
Query: 1 MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60
MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE
Sbjct: 1 MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE 60
Query: 61 WEAIQALTV 69
WEAIQALTV
Sbjct: 61 WEAIQALTV 69
>gi|131888135 target of myb1-like 2 isoform 3 [Homo sapiens]
Length = 507
Score = 93.6 bits (231), Expect = 4e-19
Identities = 74/283 (26%), Positives = 132/283 (46%), Gaps = 21/283 (7%)
Query: 14 INRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEW-EAIQALTVLET 72
+ +AT+ + DW C+ +NE EGP A R L ++ + + E + ALTVLET
Sbjct: 17 LEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLNGNRNYREVMLALTVLET 76
Query: 73 CMKSCGKRFHDEVGKFRFLNE-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGL---PE 128
C+K+CG RFH V F++ L+K++SPK + V++K+L L+ +W P+
Sbjct: 77 CVKNCGHRFHILVANRDFIDSVLVKIISPK---NNPPTIVQDKVLALIQAWADAFRSSPD 133
Query: 129 EVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPR-------PKNVIFEDEEKSKMLARL 181
+ Y+ LK++G+ P D P+ P+ P + + + + A
Sbjct: 134 LTGVVHIYEELKRKGV--EFPMADLDALSPIHTPQRSVPEVDPAATMPRSQSQQRTSAGS 191
Query: 182 LKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAA 241
S P A + E+I++ + ++ V N K+++EM ++ G
Sbjct: 192 YSSPPPAPYSAPQAPALSVTGPITANSEQIARLRSELDVVRGNTKVMSEM-LTEMVPGQE 250
Query: 242 AGSSEDLMKELYQRCERMRPTLFRL---ASDTEDNDEALGLSD 281
S +L++EL + C M+ + L S+ E +E L ++D
Sbjct: 251 DSSDLELLQELNRTCRAMQQRIVELISRVSNEEVTEELLHVND 293
>gi|71773010 adaptor-related protein complex 1, gamma 1 subunit
isoform a [Homo sapiens]
Length = 825
Score = 92.0 bits (227), Expect = 1e-18
Identities = 72/251 (28%), Positives = 118/251 (47%), Gaps = 29/251 (11%)
Query: 299 QSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWE 358
Q++ TEP AP +E++PP P S D LDLLG + +P
Sbjct: 603 QTNGETEP-------AP-LETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTS---- 650
Query: 359 KQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLE 418
+ + L DL + +P+++ P P PQ P L + PL
Sbjct: 651 -KPSSAGGELLDLLGDINLTGAPAAA---------PAPASVPQISQPPFLLDGLSSQPLF 700
Query: 419 SIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVP 478
+ + I +T Y ++G +I F F R V V+ + ++ + + VFQ+AVP
Sbjct: 701 NDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQAAVP 758
Query: 479 KVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMG 538
K +++L PS + +PAFN ITQV+ + NPQK+++R+R KLT+ ++
Sbjct: 759 KTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLA 814
Query: 539 DVDQFPPPETW 549
+V+ F PP++W
Sbjct: 815 EVNNF-PPQSW 824
>gi|71772942 adaptor-related protein complex 1, gamma 1 subunit
isoform b [Homo sapiens]
Length = 822
Score = 92.0 bits (227), Expect = 1e-18
Identities = 72/251 (28%), Positives = 118/251 (47%), Gaps = 29/251 (11%)
Query: 299 QSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWE 358
Q++ TEP AP +E++PP P S D LDLLG + +P
Sbjct: 600 QTNGETEP-------AP-LETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTS---- 647
Query: 359 KQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLE 418
+ + L DL + +P+++ P P PQ P L + PL
Sbjct: 648 -KPSSAGGELLDLLGDINLTGAPAAA---------PAPASVPQISQPPFLLDGLSSQPLF 697
Query: 419 SIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVP 478
+ + I +T Y ++G +I F F R V V+ + ++ + + VFQ+AVP
Sbjct: 698 NDIAAGIPSITAYSKNGLKIEFTFERSNT--NPSVTVITIQASNSTELDMTDFVFQAAVP 755
Query: 479 KVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMG 538
K +++L PS + +PAFN ITQV+ + NPQK+++R+R KLT+ ++
Sbjct: 756 KTFQLQLLSPSSSIVPAFNT----GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLA 811
Query: 539 DVDQFPPPETW 549
+V+ F PP++W
Sbjct: 812 EVNNF-PPQSW 821
>gi|209180457 target of myb1 isoform 2 [Homo sapiens]
Length = 493
Score = 91.3 bits (225), Expect = 2e-18
Identities = 104/392 (26%), Positives = 176/392 (44%), Gaps = 50/392 (12%)
Query: 13 RINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEW-EAIQALTVLE 71
RI +AT+ + DWA C+ +NE EGP A R + +I + + E + ALTVLE
Sbjct: 16 RIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLE 75
Query: 72 TCMKSCGKRFHDEVGKFRFLNE-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGL---P 127
TC+K+CG RFH V F+ L++ + PK + V +K+L L+ SW P
Sbjct: 76 TCVKNCGHRFHVLVASQDFVESVLVRTILPK---NNPPTIVHDKVLNLIQSWADAFRSSP 132
Query: 128 EEVKIAEAYQMLKKQGIVKSDPKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSH 186
+ + Y+ L+++G+ + P D P P+ +F E +S + SS
Sbjct: 133 DLTGVVTIYEDLRRKGL-----EFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQ 187
Query: 187 PED--LRAANKLIKEMVQED---QKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAA 241
ED AA ++ D E+I K + +E V+ NV++++EM ++ A
Sbjct: 188 QEDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEM-LTELVPTQA 246
Query: 242 AGSSEDLMKELYQRCERMRPTLFRL---ASDTEDNDEALGLSDPTPPSGPSLDGTGWNSF 298
+ +L++EL + C M+ + L ++ + +E L ++D + L + F
Sbjct: 247 EPADLELLQELNRTCRAMQQRVLELIPQIANEQLTEELLIVNDNL--NNVFLRHERFERF 304
Query: 299 QSSDATEPPAPALAQAPSMESRP-PAQT----------------------SLPASSGL-D 334
++ T+ P+ A A ++ P PA T SL AS L D
Sbjct: 305 RTGQTTKAPSEAEPAADLIDMGPDPAATGNLSSQLAGMNLGSSSVRAGLQSLEASGRLED 364
Query: 335 DLDLLGKTLLQQSLPPESQQVRWEKQQPTPRL 366
+ D+ T SL + ++V++E Q T L
Sbjct: 365 EFDMFALT-RGSSLADQRKEVKYEAPQATDGL 395
>gi|4885637 target of myb1 isoform 1 [Homo sapiens]
Length = 492
Score = 91.3 bits (225), Expect = 2e-18
Identities = 104/392 (26%), Positives = 176/392 (44%), Gaps = 50/392 (12%)
Query: 13 RINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEW-EAIQALTVLE 71
RI +AT+ + DWA C+ +NE EGP A R + +I + + E + ALTVLE
Sbjct: 16 RIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLE 75
Query: 72 TCMKSCGKRFHDEVGKFRFLNE-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGL---P 127
TC+K+CG RFH V F+ L++ + PK + V +K+L L+ SW P
Sbjct: 76 TCVKNCGHRFHVLVASQDFVESVLVRTILPK---NNPPTIVHDKVLNLIQSWADAFRSSP 132
Query: 128 EEVKIAEAYQMLKKQGIVKSDPKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSH 186
+ + Y+ L+++G+ + P D P P+ +F E +S + SS
Sbjct: 133 DLTGVVTIYEDLRRKGL-----EFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQ 187
Query: 187 PED--LRAANKLIKEMVQED---QKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAA 241
ED AA ++ D E+I K + +E V+ NV++++EM ++ A
Sbjct: 188 QEDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEM-LTELVPTQA 246
Query: 242 AGSSEDLMKELYQRCERMRPTLFRL---ASDTEDNDEALGLSDPTPPSGPSLDGTGWNSF 298
+ +L++EL + C M+ + L ++ + +E L ++D + L + F
Sbjct: 247 EPADLELLQELNRTCRAMQQRVLELIPQIANEQLTEELLIVNDNL--NNVFLRHERFERF 304
Query: 299 QSSDATEPPAPALAQAPSMESRP-PAQT----------------------SLPASSGL-D 334
++ T+ P+ A A ++ P PA T SL AS L D
Sbjct: 305 RTGQTTKAPSEAEPAADLIDMGPDPAATGNLSSQLAGMNLGSSSVRAGLQSLEASGRLED 364
Query: 335 DLDLLGKTLLQQSLPPESQQVRWEKQQPTPRL 366
+ D+ T SL + ++V++E Q T L
Sbjct: 365 EFDMFALT-RGSSLADQRKEVKYEAPQATDGL 395
>gi|209180448 target of myb1 isoform 3 [Homo sapiens]
Length = 460
Score = 82.0 bits (201), Expect = 1e-15
Identities = 97/371 (26%), Positives = 166/371 (44%), Gaps = 50/371 (13%)
Query: 34 CEQLNEDFEGPPLATRLLAHKIQSPQEW-EAIQALTVLETCMKSCGKRFHDEVGKFRFLN 92
C+ +NE EGP A R + +I + + E + ALTVLETC+K+CG RFH V F+
Sbjct: 4 CDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHVLVASQDFVE 63
Query: 93 E-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGL---PEEVKIAEAYQMLKKQGIVKSD 148
L++ + PK + V +K+L L+ SW P+ + Y+ L+++G+
Sbjct: 64 SVLVRTILPK---NNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVTIYEDLRRKGL---- 116
Query: 149 PKLP-DDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSHPED--LRAANKLIKEMVQED- 204
+ P D P P+ +F E +S + SS ED AA ++ D
Sbjct: 117 -EFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQQEDSGQHAAPLPAPPILSGDT 175
Query: 205 --QKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSSEDLMKELYQRCERMRPT 262
E+I K + +E V+ NV++++EM ++ A + +L++EL + C M+
Sbjct: 176 PIAPTPEQIGKLRSELEMVSGNVRVMSEM-LTELVPTQAEPADLELLQELNRTCRAMQQR 234
Query: 263 LFRL---ASDTEDNDEALGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMES 319
+ L ++ + +E L ++D + L + F++ T+ P+ A A ++
Sbjct: 235 VLELIPQIANEQLTEELLIVNDNL--NNVFLRHERFERFRTGQTTKAPSEAEPAADLIDM 292
Query: 320 RP-PAQT----------------------SLPASSGL-DDLDLLGKTLLQQSLPPESQQV 355
P PA T SL AS L D+ D+ T SL + ++V
Sbjct: 293 GPDPAATGNLSSQLAGMNLGSSSVRAGLQSLEASGRLEDEFDMFALT-RGSSLADQRKEV 351
Query: 356 RWEKQQPTPRL 366
++E Q T L
Sbjct: 352 KYEAPQATDGL 362
>gi|191252812 target of myb1-like 1 [Homo sapiens]
Length = 476
Score = 80.1 bits (196), Expect = 5e-15
Identities = 109/512 (21%), Positives = 203/512 (39%), Gaps = 87/512 (16%)
Query: 14 INRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQ-ALTVLET 72
I +AT + DW C+ +N +GP A + L +I + IQ L++++
Sbjct: 19 IEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDM 78
Query: 73 CMKSCGKRFHDEVGKFRFLNE-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPEEV- 130
C+++CG F + K F+ E L+K+++P+Y ++N+IL + +W+ G P V
Sbjct: 79 CVQNCGPSFQSLIVKKEFVKENLVKLLNPRY---NLPLDIQNRILNFIKTWSQGFPGGVD 135
Query: 131 --KIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSHPE 188
++ E Y L K+G+ PP + E ++ + S+ P
Sbjct: 136 VSEVKEVYLDLVKKGV-------------QFPPSE------AEAETARQETAQISSNPPT 176
Query: 189 DLRAANKLIKEMVQEDQKRM---EKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSS 245
+ A L + ++ E+I K + ++ V NV++++ ++M ++ G
Sbjct: 177 SVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDI 236
Query: 246 EDLMKELYQRCERMRPTLFRLASDTEDNDEALGLSDPTPPSGPSLDGTGWNSFQSSDATE 305
E L+++LY+ M+ + L E+ D + L ++ G+ F +
Sbjct: 237 E-LLQKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAI--LGYERFTRNQ--- 290
Query: 306 PPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPR 365
+ + + TS P++ D LDL PR
Sbjct: 291 ---QRILEQNKNQKEATNTTSEPSAPSQDLLDL-------------------SPSPRMPR 328
Query: 366 LTLRDLQNKSSSCSS-----PSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESI 420
TL +L ++ S PSS T+ L +P P L+L + +P +
Sbjct: 329 ATLGELNTMNNQLSGLNFSLPSSDVTNNL--------KPSLHPQMNLLALENTEIPPFAQ 380
Query: 421 KPS-NILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIV--FQSAV 477
+ S N+ YD L + V + VS+ + A P + S
Sbjct: 381 RTSQNLTSSHAYDNF------------LEHSNSVFLQPVSLQTIAAAPSNQSLPPLPSNH 428
Query: 478 PKVMKVKLQPPSGTELPAFNPIVHPSAITQVL 509
P + K LQPP+ E+ F+P+ P+ T+ +
Sbjct: 429 PAMTKSDLQPPNYYEVMEFDPLA-PAVTTEAI 459
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 68.6 bits (166), Expect = 1e-11
Identities = 44/148 (29%), Positives = 71/148 (47%), Gaps = 8/148 (5%)
Query: 9 TLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQALT 68
T E +++AT+ L E DW SI C+ + + A + K+ A+ AL
Sbjct: 7 TFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALE 66
Query: 69 VLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPE 128
V+E+ +K+CG+ HDEV + + EL L + V+NKIL L+ +W
Sbjct: 67 VMESVVKNCGQTVHDEVANKQTMEEL-----KDLLKRQVEVNVRNKILYLIQAWAHAFRN 121
Query: 129 EVK---IAEAYQMLKKQGIVKSDPKLPD 153
E K + + YQ++K +G V + K D
Sbjct: 122 EPKYKVVQDTYQIMKVEGHVFPEFKESD 149
>gi|209180450 target of myb1 isoform 4 [Homo sapiens]
Length = 447
Score = 67.8 bits (164), Expect = 2e-11
Identities = 93/362 (25%), Positives = 152/362 (41%), Gaps = 35/362 (9%)
Query: 13 RINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEW-EAIQALTVLE 71
RI +AT+ + DWA C+ +NE EGP A R + +I + + E + ALTVLE
Sbjct: 16 RIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLE 75
Query: 72 TCMKSCGKRFHDEVGKFRFLNE-LIKVVSPK-YLGSRTSEKVKNKILELLYSWTVGLPEE 129
TC+K+CG RFH V F+ L++ + PK + +KV N I + S T +
Sbjct: 76 TCVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQTVFNSETQSGQDS 135
Query: 130 VKIAEAYQMLKKQ--GIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKS---KMLARLLKS 184
V + Q Q + + P L DT P + + E E S ++++ +L
Sbjct: 136 VGTDSSQQEDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTE 195
Query: 185 SHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGS 244
P A+ E++QE + + +RV + N +L E+++ +
Sbjct: 196 LVPTQAEPAD---LELLQELNRTCRAMQQRVLELIPQIANEQLTEELLIVN--------- 243
Query: 245 SEDLMKELYQRCERMRPTLFRLASDTEDNDEALGLSDPTPPSGPSLDGTGWNSFQSSDAT 304
D + ++ R ER FR T+ EA +D GP TG S Q +
Sbjct: 244 --DNLNNVFLRHERFE--RFRTGQTTKAPSEAEPAAD-LIDMGPDPAATGNLSSQLAGMN 298
Query: 305 EPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTP 364
+ A S+E+ + D+ D+ T SL + ++V++E Q T
Sbjct: 299 LGSSSVRAGLQSLEASGRLE---------DEFDMFALT-RGSSLADQRKEVKYEAPQATD 348
Query: 365 RL 366
L
Sbjct: 349 GL 350
>gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [Homo
sapiens]
Length = 785
Score = 65.9 bits (159), Expect = 9e-11
Identities = 44/163 (26%), Positives = 83/163 (50%), Gaps = 8/163 (4%)
Query: 388 LLHTVSPEPPRPPQ-QPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDP 446
LL S + PP P P + + +P P+ I + V+++ G ++ F R P
Sbjct: 629 LLDGASGDVQHPPHLDPSPGGALVHLLDLPCVPPPPAPIPDLKVFEREGVQLNLSFIRPP 688
Query: 447 LPGRSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAIT 506
+L++ ++ + + + + + Q+AVPK ++++LQ PSG +PA + IT
Sbjct: 689 --ENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGGL----PIT 742
Query: 507 QVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETW 549
Q+ + NP K +RL+ +LT+ Q+ E+ +V+ P E+W
Sbjct: 743 QLFRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNL-PVESW 784
>gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]
Length = 540
Score = 64.3 bits (155), Expect = 3e-10
Identities = 40/145 (27%), Positives = 68/145 (46%), Gaps = 9/145 (6%)
Query: 3 PAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWE 62
P + + +AT+ +N DW I C+++ + GP R + ++
Sbjct: 2 PLFATNPFDQDVEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHV 61
Query: 63 AIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSW 122
A+QALT+L C+ +CGK FH EV F +E+ V+ ++ KV K+ L+ W
Sbjct: 62 AMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVL------NKGHPKVCEKLKALMVEW 115
Query: 123 TVGL---PEEVKIAEAYQMLKKQGI 144
T P+ I+ + LK+QG+
Sbjct: 116 TDEFKNDPQLSLISAMIKNLKEQGV 140
Score = 30.4 bits (67), Expect = 4.4
Identities = 62/284 (21%), Positives = 108/284 (38%), Gaps = 40/284 (14%)
Query: 137 QMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSHPED------- 189
+M+K + K + DD P P+ F DE+K L ++L+S+ P D
Sbjct: 273 EMIKTE---KKTVQFSDDVQVETIEPEPEPA-FIDEDKMDQLLQMLQSTDPSDDQPDLPE 328
Query: 190 LRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSSEDLM 249
L + +M +++E I ++ + + E+ NVK++ + + +ED M
Sbjct: 329 LLHLEAMCHQMGPLIDEKLEDIDRKHSELSEL--NVKVMEALSLYTKL------MNEDPM 380
Query: 250 KELYQRCERMRPTLFRLASDTEDNDEALGLSDPTPPSGPSL--DGTGWNSFQSSDATEPP 307
+Y + + + +S + G PPSG L + QS
Sbjct: 381 YSMYAKLQNQ--PYYMQSSGVSGSQVYAG----PPPSGAYLVAGNAQMSHLQSYSLPPEQ 434
Query: 308 APALAQA---PSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTP 364
+L+QA PS P+Q + A + G T Q+ P S T
Sbjct: 435 LSSLSQAVVPPSANPALPSQQTQAAYPNTMVSSVQGNTYPSQA-PVYSPPPAATAAAATA 493
Query: 365 RLTLRDLQNKSSSCSSPSSSATSLLHTVSPEP-----PRPPQQP 403
+TL +++ + P +L + P+P P PQQP
Sbjct: 494 DVTL----YQNAGPNMPQVPNYNLTSSTLPQPGGSQQPPQPQQP 533
>gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]
Length = 525
Score = 60.8 bits (146), Expect = 3e-09
Identities = 53/226 (23%), Positives = 95/226 (42%), Gaps = 27/226 (11%)
Query: 3 PAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWE 62
P E + +ATN N DW+ I C+++ G + + ++
Sbjct: 2 PLFTANPFEQDVEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPHV 61
Query: 63 AIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSW 122
A+QALT+L C+ +CGK FH EV F E+ V+ ++ KV K+ L+ W
Sbjct: 62 ALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIK-----NKAHPKVCEKLKSLMVEW 116
Query: 123 TVGL---PEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLA 179
+ P+ I+ + +K++GI TFP + + ++ S
Sbjct: 117 SEEFQKDPQFSLISATIKSMKEEGI-----------TFPPAGSQTVSAAAKNGTSSN--- 162
Query: 180 RLLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNV 225
K+ ED+ A +L + ++ Q+ E S ++ ++NN V
Sbjct: 163 ---KNKEDEDIAKAIEL--SLQEQKQQHTETKSLYPSSEIQLNNKV 203
>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 53.5 bits (127), Expect = 5e-07
Identities = 46/148 (31%), Positives = 59/148 (39%), Gaps = 17/148 (11%)
Query: 282 PTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGK 341
P PS + ++ + A P PA AP S PP T+ P +
Sbjct: 192 PPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATT-----P 246
Query: 342 TLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQ 401
L S PPE+ V PTP T D SS S+P + T+ T S P PP
Sbjct: 247 APLSSSAPPETTAV-----PPTPSATTLD----PSSASAPPET-TAAPPTPSATTPAPPS 296
Query: 402 QPVPTELSLASITVPLESIKPSNILPVT 429
P P E + A IT P S P+ + P T
Sbjct: 297 SPAPQETTAAPITTPNSS--PTTLAPDT 322
>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 53.5 bits (127), Expect = 5e-07
Identities = 46/148 (31%), Positives = 59/148 (39%), Gaps = 17/148 (11%)
Query: 282 PTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGK 341
P PS + ++ + A P PA AP S PP T+ P +
Sbjct: 192 PPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATT-----P 246
Query: 342 TLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQ 401
L S PPE+ V PTP T D SS S+P + T+ T S P PP
Sbjct: 247 APLSSSAPPETTAV-----PPTPSATTLD----PSSASAPPET-TAAPPTPSATTPAPPS 296
Query: 402 QPVPTELSLASITVPLESIKPSNILPVT 429
P P E + A IT P S P+ + P T
Sbjct: 297 SPAPQETTAAPITTPNSS--PTTLAPDT 322
>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 53.5 bits (127), Expect = 5e-07
Identities = 46/148 (31%), Positives = 59/148 (39%), Gaps = 17/148 (11%)
Query: 282 PTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGK 341
P PS + ++ + A P PA AP S PP T+ P +
Sbjct: 192 PPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATT-----P 246
Query: 342 TLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQ 401
L S PPE+ V PTP T D SS S+P + T+ T S P PP
Sbjct: 247 APLSSSAPPETTAV-----PPTPSATTLD----PSSASAPPET-TAAPPTPSATTPAPPS 296
Query: 402 QPVPTELSLASITVPLESIKPSNILPVT 429
P P E + A IT P S P+ + P T
Sbjct: 297 SPAPQETTAAPITTPNSS--PTTLAPDT 322
>gi|118918413 MICAL C-terminal like [Homo sapiens]
Length = 695
Score = 42.7 bits (99), Expect = 9e-04
Identities = 56/218 (25%), Positives = 78/218 (35%), Gaps = 54/218 (24%)
Query: 221 VNNNVKLLTEMVMSHSQGGAAAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALGLS 280
+ N ++ E ++S+S+GG A + ++ Q C R R + +D D+
Sbjct: 273 IANAIRRSLEPLLSNSEGGKKAWAKQESKTLPAQACTRSFS--LRKTNSNKDGDQ----- 325
Query: 281 DPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRP----PAQTSLPASSGLDDL 336
G N S A PP PAL + S+ +RP PA S P S D
Sbjct: 326 ----------HSPGRNQ---SSAFSPPDPAL-RTHSLPNRPSKVFPALRSPPCSKIEDVP 371
Query: 337 DLLGKTLLQQSLPPESQQVRWE-----------------KQQPTPRLTLRDLQNKSSSCS 379
LL K LQ++ P S+ + Q+ R +RDL
Sbjct: 372 TLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKV 431
Query: 380 SPSSSA------------TSLLHTVSPEPPRPPQQPVP 405
P SA TSL P PP PP P P
Sbjct: 432 LPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPP 469
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 42.4 bits (98), Expect = 0.001
Identities = 65/277 (23%), Positives = 93/277 (33%), Gaps = 27/277 (9%)
Query: 158 PLPPPRPKNVIFEDEEKSKMLARLLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNA 217
PLPP V+ E +R SS + ++ ++++ K V+A
Sbjct: 526 PLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSA 585
Query: 218 IEEV--NNNVKLLTEMVMSHSQGGAAAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDE 275
NN +++ +Q AAAGS + M + + TL R
Sbjct: 586 AVPAPGRNN----SQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPP 641
Query: 276 ALGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSME--SRPPAQTSLPASSGL 333
G P P G S GT Q + P P + +P + +PP Q S P+
Sbjct: 642 KPGNPPPGHPGGQSSSGTS----QHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPS---- 693
Query: 334 DDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVS 393
L SL P Q PT L + K +S P+ A H +
Sbjct: 694 ---QLSAPRRYSSSLSPIQAPNHPPPQPPTQATPL--MHTKPNSQGPPNPMALPSEHGLE 748
Query: 394 PEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTV 430
PPQ P P T PL PS P T+
Sbjct: 749 QPSHTPPQTPTPPS------TPPLGKQNPSLPAPQTL 779
>gi|76563940 synuclein alpha interacting protein [Homo sapiens]
Length = 919
Score = 42.0 bits (97), Expect = 0.001
Identities = 59/249 (23%), Positives = 97/249 (38%), Gaps = 36/249 (14%)
Query: 163 RPKNVIFEDEEKSKMLARLLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVN 222
RPK +DE+ K+L +LL E++ KL E +D + + SK++ +
Sbjct: 608 RPKA---KDEDSDKILRQLLGKEISENVCTQEKLSLEF--QDAQASSRNSKKIPLEKREL 662
Query: 223 NNVKLLTEMVMSHSQGGAAAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALGL--S 280
+L M S S+ + +SED ++ +R RP + ++ D+ E+L L
Sbjct: 663 KLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRPRPQPIVESVESMDSAESLHLMIK 722
Query: 281 DPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLG 340
T SG + +S D P + + P +ES+ P S+P +
Sbjct: 723 KHTLASGGRRFPFSIKASKSLDGHSPSPTSESSEPDLESQYPGSGSIPPN---------- 772
Query: 341 KTLLQQSLPPESQQVRWEKQQPTPRLTL--RDLQNKSSSCSSPSS----SATSLLHTVSP 394
Q + QQP+P T + + S+ SPSS S L
Sbjct: 773 -------------QPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRVTFE 819
Query: 395 EPPRPPQQP 403
EP +QP
Sbjct: 820 EPVVQMEQP 828
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/204 (25%), Positives = 69/204 (33%), Gaps = 21/204 (10%)
Query: 229 TEMVMSHSQGGAAAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALGLSDPTPPSGP 288
+++ +Q AAAGS + M + + TL R G P P G
Sbjct: 517 SQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQ 576
Query: 289 SLDGTGWNSFQSSDATEPPAPALAQAPSME--SRPPAQTSLPASSGLDDLDLLGKTLLQQ 346
S GT Q + P P + +P + +PP Q S P+ L
Sbjct: 577 SSSGTS----QHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPS-------QLSAPRRYSS 625
Query: 347 SLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPT 406
SL P Q PT L + K +S P+ A H + PPQ P P
Sbjct: 626 SLSPIQAPNHPPPQPPTQATPL--MHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPP 683
Query: 407 ELSLASITVPLESIKPSNILPVTV 430
T PL PS P T+
Sbjct: 684 S------TPPLGKQNPSLPAPQTL 701
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 40.4 bits (93), Expect = 0.004
Identities = 38/186 (20%), Positives = 73/186 (39%), Gaps = 8/186 (4%)
Query: 138 MLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSHPEDLRAANKLI 197
M ++Q DP D+ P + + E E K + R KS + A KL
Sbjct: 1716 MKRQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQ-KSKQQAKIEATQKLE 1774
Query: 198 KEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSSEDLMKELYQRCE 257
+ ++ Q++ ++ + ++ ++ + ++ G ++ KEL+ +
Sbjct: 1775 QVKNEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQP 1834
Query: 258 RMRPTLFRLASDTEDNDEALGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSM 317
PT T +D + P PP PS +S + ++PP+P + S
Sbjct: 1835 PSTPT------STSSDDVFVKPQAPPPPPAPSRIPIQ-DSLSQAQTSQPPSPQVFSPGSS 1887
Query: 318 ESRPPA 323
SRPP+
Sbjct: 1888 NSRPPS 1893
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 39.7 bits (91), Expect = 0.007
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 333 LDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSS---CSSPSSSATSLL 389
L D+D L + PP + R ++ TP LT R + S S SS SS S+L
Sbjct: 1223 LSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSIL 1282
Query: 390 HTVSPEPPRPPQQPVPTEL 408
+++P+ P P +P +L
Sbjct: 1283 DSLNPQSPPPLLASMPAQL 1301
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 39.7 bits (91), Expect = 0.007
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 8/85 (9%)
Query: 280 SDPTPPSGPS-----LDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGLD 334
SDP+PPS + L T + Q+S A P P + P + RPP+ + P S
Sbjct: 2371 SDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPL 2430
Query: 335 DLDLLGKTLLQQSLPPESQQVRWEK 359
+ + T LQ SLPP+ Q + ++
Sbjct: 2431 QISM---TSLQNSLPPQLLQYQCDQ 2452
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 39.7 bits (91), Expect = 0.007
Identities = 40/156 (25%), Positives = 64/156 (41%), Gaps = 9/156 (5%)
Query: 274 DEALGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGL 333
D L+ P P+ P+ + S PP+ AL+ ++ PP QT GL
Sbjct: 2798 DSPTSLAPPLAPAAPTPPSV---TVSPSSPPTPPSQALSSLKAVG--PPPQTPPRRHRGL 2852
Query: 334 DDLDLLGKTLLQQSLPP-ESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTV 392
TL + P E + + P P T + ++ SSS +P TS +
Sbjct: 2853 QAARPAEPTLPSTHVTPSEPKPFVLDTGTPIPASTPQGVKPVSSS--TPVYVVTSFVSAP 2910
Query: 393 -SPEPPRPPQQPVPTELSLASITVPLESIKPSNILP 427
+PEPP P P PT++++ S++ E + P
Sbjct: 2911 PAPEPPAPEPPPEPTKVTVQSLSPAKEVVSSPGSSP 2946
Score = 39.3 bits (90), Expect = 0.009
Identities = 40/138 (28%), Positives = 57/138 (41%), Gaps = 17/138 (12%)
Query: 276 ALGLSDPTPPSGPSLDGTGW------NSFQSSDATEPPAPALAQAPSMESRP-PAQTSLP 328
AL + P+ P+ PS ++ SDA +PPAP AQ + E RP P + S P
Sbjct: 2169 ALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKP 2228
Query: 329 ASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSL 388
A L L L + +S Q+ Q P+ Q ++ S P A
Sbjct: 2229 APPP-QALQTLALPLTPYAQIIQSLQLSGHAQGPS--------QGPAAPPSEPKPHAAVF 2279
Query: 389 LHTVSPEPPRPPQQPVPT 406
SP PP P++ VP+
Sbjct: 2280 ARVASP-PPGAPEKRVPS 2296
Score = 30.0 bits (66), Expect = 5.8
Identities = 38/147 (25%), Positives = 55/147 (37%), Gaps = 11/147 (7%)
Query: 381 PSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILF 440
P S TSL ++P P PP V + L S+K P T +H
Sbjct: 2796 PPDSPTSLAPPLAPAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQTPPRRHRGLQAA 2855
Query: 441 HFARDPLPG--------RSDVLVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTE 492
A LP + VL + ++ PQ ++ + + V V PP+ E
Sbjct: 2856 RPAEPTLPSTHVTPSEPKPFVLDTGTPIPASTPQGVKPVSSSTPVYVVTSFVSAPPA-PE 2914
Query: 493 LPAFNPIVHPSAITQVLLLANPQKEKV 519
PA P P+ +T L +P KE V
Sbjct: 2915 PPAPEPPPEPTKVTVQSL--SPAKEVV 2939
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,560,677
Number of Sequences: 37866
Number of extensions: 1367389
Number of successful extensions: 8886
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 457
Number of HSP's that attempted gapping in prelim test: 7585
Number of HSP's gapped (non-prelim): 1661
length of query: 552
length of database: 18,247,518
effective HSP length: 107
effective length of query: 445
effective length of database: 14,195,856
effective search space: 6317155920
effective search space used: 6317155920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.