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Search of human proteins with 13375827
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13375827 phafin 2 [Homo sapiens]
(249 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13375827 phafin 2 [Homo sapiens] 516 e-147
gi|153791377 apoptosis-inducing protein D [Homo sapiens] 294 6e-80
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens] 124 8e-29
gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens] 89 4e-18
gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens] 86 2e-17
gi|24797153 faciogenital dysplasia protein [Homo sapiens] 85 7e-17
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens] 78 8e-15
gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens] 75 5e-14
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 72 3e-13
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 72 6e-13
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 71 8e-13
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 71 8e-13
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 71 8e-13
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 70 1e-12
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 70 1e-12
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 70 2e-12
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 70 2e-12
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 69 4e-12
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 65 7e-11
gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform... 63 3e-10
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 62 6e-10
gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 60 1e-09
gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 60 1e-09
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 60 2e-09
gi|217272865 myotubularin related protein 4 [Homo sapiens] 60 2e-09
gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo sa... 60 2e-09
gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens] 60 2e-09
gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform... 59 4e-09
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 59 5e-09
gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Hom... 55 4e-08
>gi|13375827 phafin 2 [Homo sapiens]
Length = 249
Score = 516 bits (1330), Expect = e-147
Identities = 249/249 (100%), Positives = 249/249 (100%)
Query: 1 MVDRLANSEANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFND 60
MVDRLANSEANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFND
Sbjct: 1 MVDRLANSEANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFND 60
Query: 61 ILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKS 120
ILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKS
Sbjct: 61 ILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKS 120
Query: 121 EWMNHINKCVTDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGF 180
EWMNHINKCVTDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGF
Sbjct: 121 EWMNHINKCVTDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGF 180
Query: 181 VVCGPCSEKRFLLPSQSSKPVRICDFCYDLLSAGDMATCQPARSDSYSQSLKSPLNDMSD 240
VVCGPCSEKRFLLPSQSSKPVRICDFCYDLLSAGDMATCQPARSDSYSQSLKSPLNDMSD
Sbjct: 181 VVCGPCSEKRFLLPSQSSKPVRICDFCYDLLSAGDMATCQPARSDSYSQSLKSPLNDMSD 240
Query: 241 DDDDDDSSD 249
DDDDDDSSD
Sbjct: 241 DDDDDDSSD 249
>gi|153791377 apoptosis-inducing protein D [Homo sapiens]
Length = 279
Score = 294 bits (752), Expect = 6e-80
Identities = 141/252 (55%), Positives = 176/252 (69%), Gaps = 3/252 (1%)
Query: 1 MVDRLANSEANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFND 60
MVD LAN+E N++RI+ VE+CFGA+GQPL +PGRVL+GEGVLTK CRKK K R FFLFND
Sbjct: 1 MVDHLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFND 60
Query: 61 ILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKS 120
ILVYG+IV+ K+KY QHIIPLE VT++ + + +N W+IKT KSF V AA+ATE+
Sbjct: 61 ILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQ 120
Query: 121 EWMNHINKCVTDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGF 180
EW++HI +CV L +G+ PS EHAA W+PD +CMRC + +F+ + RRHHCRKCGF
Sbjct: 121 EWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGF 180
Query: 181 VVCGPCSEKRFLLPSQSSKPVRICDFCYDLLSA---GDMATCQPARSDSYSQSLKSPLND 237
VVC CS +RFLLP S KPVR+C CY L+A + A Q A S L P+
Sbjct: 181 VVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICG 240
Query: 238 MSDDDDDDDSSD 249
S DDDD D
Sbjct: 241 ASSGDDDDSDED 252
>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
Length = 1430
Score = 124 bits (311), Expect = 8e-29
Identities = 74/229 (32%), Positives = 115/229 (50%), Gaps = 25/229 (10%)
Query: 32 PGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDSIK 91
PGRV + EG+L KL RK + R FFLFND L+Y +Q Y +++ L + +
Sbjct: 1086 PGRVFLKEGILMKLSRKVMQPRMFFLFNDALLY-TTPVQSGMYKLNNMLSLAGMKVRKPT 1144
Query: 92 DEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCV------------------TDL 133
E +N I++ +SF + A++ATE+ EW+ I++ + D
Sbjct: 1145 QEA-YQNELKIESVERSFILSASSATERDEWLEAISRAIEEYAKKRITFCPSRSLDEADS 1203
Query: 134 LSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLL 193
+K +P A +W+PD+ AT+CM C ++FT RRHHCR CG +VC CS ++ L
Sbjct: 1204 ENKEEVSPLGSKAPIWIPDTRATMCMICT-SEFTLTWRRHHCRACGKIVCQACSSNKYGL 1262
Query: 194 PSQSSKPVRICDFCYDLLSAGDMATC----QPARSDSYSQSLKSPLNDM 238
++P R+C+ C+ L D P S S +L S L+ +
Sbjct: 1263 DYLKNQPARVCEHCFQELQKLDHQHSPRIGSPGNHKSPSSALSSVLHSI 1311
>gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens]
Length = 766
Score = 89.0 bits (219), Expect = 4e-18
Identities = 52/202 (25%), Positives = 96/202 (47%), Gaps = 22/202 (10%)
Query: 32 PGRVLIGEGVLTKLCRKKPKA--RQFFLFNDILVY--GNIVIQKKKYNKQHIIPLENVTI 87
P LI EG + KL + A R FLFN++L+Y + K+ + + ++ + I
Sbjct: 419 PSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKI 478
Query: 88 DSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCV----------------- 130
++E + + + + ++ + A++A +K EW+ + + +
Sbjct: 479 VETQNE-EYPHTFQVSGKERTLELQASSAQDKEEWIKALQETIDAFHQRHETFRNAIAKD 537
Query: 131 TDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKR 190
D+ S+ + A W+ D+E T+CM+C++ RRHHCR CG+VVC CS+ +
Sbjct: 538 NDIHSEVSTAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYK 597
Query: 191 FLLPSQSSKPVRICDFCYDLLS 212
L K ++C CY ++S
Sbjct: 598 AQLEYDGGKLSKVCKDCYQIIS 619
>gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens]
Length = 655
Score = 86.3 bits (212), Expect = 2e-17
Identities = 56/205 (27%), Positives = 91/205 (44%), Gaps = 26/205 (12%)
Query: 32 PGRVLIGEGVLTKLC--RKKPKARQFFLFNDILVY--GNIVIQKKKYNKQHIIPLENVTI 87
P L+ EG + K+ R P R FLFN++L+Y ++ ++ + I + + +
Sbjct: 316 PSNTLLREGPVLKISFRRNDPMERYLFLFNNMLLYCVPRVIQVGAQFQVRTRIDVAGMKV 375
Query: 88 DSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSGKT------- 140
+ D + + +L+ ++ + A + E WM + D + K +T
Sbjct: 376 RELMD-AEFPHSFLVSGKQRTLELQARSQEEMISWMQAFQAAI-DQIEKRNETFKAAAQG 433
Query: 141 PSNE-------------HAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCS 187
P + A WV D T+CMRCQ+ RRHHCR CG+VVC CS
Sbjct: 434 PEGDIQEQELQSEELGLRAPQWVRDKMVTMCMRCQEPFNALTRRRHHCRACGYVVCARCS 493
Query: 188 EKRFLLPSQSSKPVRICDFCYDLLS 212
+ R L ++P R+C CY L+
Sbjct: 494 DYRAELKYDDNRPNRVCLHCYAFLT 518
>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
Length = 961
Score = 84.7 bits (208), Expect = 7e-17
Identities = 60/206 (29%), Positives = 99/206 (48%), Gaps = 25/206 (12%)
Query: 27 QPLTIPGRVLIGEGVLTKLCRKK--PKARQFFLFNDILVY--GNIVIQKKKYNKQHIIPL 82
+ + P + LI EG + KL K + R LFND L+Y + + +K++ + I +
Sbjct: 582 EDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYCVPRLRLLGQKFSVRARIDV 641
Query: 83 ENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTD---------L 133
+ + + + +L +L+ +S + A T EK +W+ IN + L
Sbjct: 642 DGMELKESSNL-NLPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTLETFKL 700
Query: 134 LSKSGK----TPSN-------EHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVV 182
L+ + + TP N + A + + E T+CMRCQ+ + RRHHC+ CG VV
Sbjct: 701 LNSTNREDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVV 760
Query: 183 CGPCSEKRFLLPSQSSKPVRICDFCY 208
CG CSE R L +++ R+C CY
Sbjct: 761 CGKCSEFRARLVYDNNRSNRVCTDCY 786
>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
Length = 2539
Score = 77.8 bits (190), Expect = 8e-15
Identities = 32/69 (46%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Query: 140 TPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSK 199
TP H WVPD ++CM C + FT NRRHHCR+CG +VC CS K+ ++
Sbjct: 1802 TPPARHQ--WVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCREN 1859
Query: 200 PVRICDFCY 208
P R+CD CY
Sbjct: 1860 PARVCDQCY 1868
>gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]
Length = 1462
Score = 75.1 bits (183), Expect = 5e-14
Identities = 60/241 (24%), Positives = 101/241 (41%), Gaps = 22/241 (9%)
Query: 11 NTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQ 70
N +++ +E+ G L PGR + EG L K+ K + R FL ND+L+Y +
Sbjct: 1090 NLQKLVHIEHSVRGQGDLLQ-PGREFLKEGTLMKVTGKNRRPRHLFLMNDVLLY-TYPQK 1147
Query: 71 KKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCV 130
KY ++ + + N+ + E + I+T + A++ E+ EW +++ +
Sbjct: 1148 DGKYRLKNTLAVANMKVSRPVME-KVPYALKIETSESCLMLSASSCAERDEWYGCLSRAL 1206
Query: 131 ---------------TDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHC 175
++ + G + E VP + +CM C F+ RRHHC
Sbjct: 1207 PEDYKAQALAAFHHSVEIRERLGVS-LGERPPTLVPVTHVMMCMNCG-CDFSLTLRRHHC 1264
Query: 176 RKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDLLSAGDMAT--CQPARSDSYSQSLKS 233
CG +VC CS ++ L + ++CD C+ L A R S S L S
Sbjct: 1265 HACGKIVCRNCSRNKYPLKYLKDRMAKVCDGCFGELKKRGRAVPGLMRERPVSMSFPLSS 1324
Query: 234 P 234
P
Sbjct: 1325 P 1325
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 72.4 bits (176), Expect = 3e-13
Identities = 33/64 (51%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Query: 148 VWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFC 207
VW+ D EAT C C+K +F+ R+HHCR CG + C CS+ LPS S KPVR+CD C
Sbjct: 571 VWLKDKEATHCKLCEK-EFSLSKRKHHCRNCGEIFCNACSDNELPLPS-SPKPVRVCDSC 628
Query: 208 YDLL 211
+ LL
Sbjct: 629 HALL 632
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 71.6 bits (174), Expect = 6e-13
Identities = 34/75 (45%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
Query: 140 TPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSK 199
T E A VWVPDS+A CM+C+ A+FT RRHHCR CG V C C + L K
Sbjct: 687 TTLGEVAPVWVPDSQAPNCMKCE-ARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRK 745
Query: 200 PVRICDFCYDLLSAG 214
R+C C+ +L G
Sbjct: 746 EARVCVICHSVLMNG 760
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 71.2 bits (173), Expect = 8e-13
Identities = 31/63 (49%), Positives = 40/63 (63%), Gaps = 2/63 (3%)
Query: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCY 208
W+ D EAT C +C+K +F+ R+HHCR CG + C CS LPS KPVR+CD C+
Sbjct: 531 WLKDDEATHCRQCEK-EFSISRRKHHCRNCGHIFCNTCSSNELALPSY-PKPVRVCDSCH 588
Query: 209 DLL 211
LL
Sbjct: 589 TLL 591
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 71.2 bits (173), Expect = 8e-13
Identities = 31/63 (49%), Positives = 40/63 (63%), Gaps = 2/63 (3%)
Query: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCY 208
W+ D EAT C +C+K +F+ R+HHCR CG + C CS LPS KPVR+CD C+
Sbjct: 531 WLKDDEATHCRQCEK-EFSISRRKHHCRNCGHIFCNTCSSNELALPSY-PKPVRVCDSCH 588
Query: 209 DLL 211
LL
Sbjct: 589 TLL 591
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 71.2 bits (173), Expect = 8e-13
Identities = 31/63 (49%), Positives = 40/63 (63%), Gaps = 2/63 (3%)
Query: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCY 208
W+ D EAT C +C+K +F+ R+HHCR CG + C CS LPS KPVR+CD C+
Sbjct: 639 WLKDDEATHCRQCEK-EFSISRRKHHCRNCGHIFCNTCSSNELALPSY-PKPVRVCDSCH 696
Query: 209 DLL 211
LL
Sbjct: 697 TLL 699
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 70.5 bits (171), Expect = 1e-12
Identities = 33/72 (45%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Query: 140 TPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSK 199
T E A VWVPDS+A CM+C+ A+FT RRHHCR CG V C C + L K
Sbjct: 687 TTLGEVAPVWVPDSQAPNCMKCE-ARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRK 745
Query: 200 PVRICDFCYDLL 211
R+C C+ +L
Sbjct: 746 EARVCVICHSVL 757
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 70.5 bits (171), Expect = 1e-12
Identities = 33/72 (45%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Query: 140 TPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSK 199
T E A VWVPDS+A CM+C+ A+FT RRHHCR CG V C C + L K
Sbjct: 687 TTLGEVAPVWVPDSQAPNCMKCE-ARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRK 745
Query: 200 PVRICDFCYDLL 211
R+C C+ +L
Sbjct: 746 EARVCVICHSVL 757
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 69.7 bits (169), Expect = 2e-12
Identities = 33/64 (51%), Positives = 38/64 (59%), Gaps = 2/64 (3%)
Query: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCY 208
WVPDSEA CM CQ KFT RRHHCR CG V CG C ++ L K R+C CY
Sbjct: 744 WVPDSEAPNCMNCQ-VKFTFTKRRHHCRACGKVFCGVCCNRKCKL-QYLEKEARVCVVCY 801
Query: 209 DLLS 212
+ +S
Sbjct: 802 ETIS 805
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 69.7 bits (169), Expect = 2e-12
Identities = 33/64 (51%), Positives = 38/64 (59%), Gaps = 2/64 (3%)
Query: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCY 208
WVPDSEA CM CQ KFT RRHHCR CG V CG C ++ L K R+C CY
Sbjct: 744 WVPDSEAPNCMNCQ-VKFTFTKRRHHCRACGKVFCGVCCNRKCKL-QYLEKEARVCVVCY 801
Query: 209 DLLS 212
+ +S
Sbjct: 802 ETIS 805
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 68.9 bits (167), Expect = 4e-12
Identities = 31/61 (50%), Positives = 38/61 (62%), Gaps = 2/61 (3%)
Query: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCY 208
W D+E CM C K F+ RRHHCR+CG + C CS K L PS S KPVR+CD C+
Sbjct: 1349 WAEDNEVQNCMACGKG-FSVTVRRHHCRQCGNIFCAECSAKNALTPS-SKKPVRVCDACF 1406
Query: 209 D 209
+
Sbjct: 1407 N 1407
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 64.7 bits (156), Expect = 7e-11
Identities = 29/61 (47%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Query: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSS-KPVRICDFC 207
WVPD C C KA FT + R+HHCR CG + C CS LP KPVR+C C
Sbjct: 814 WVPDEACGFCTAC-KAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHC 872
Query: 208 Y 208
Y
Sbjct: 873 Y 873
>gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform 1
[Homo sapiens]
Length = 1045
Score = 62.8 bits (151), Expect = 3e-10
Identities = 42/128 (32%), Positives = 69/128 (53%), Gaps = 3/128 (2%)
Query: 29 LTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQH-IIPLENVTI 87
L +PGR I G L+KL K + R FFLFND+L+Y + + K H +PL +TI
Sbjct: 753 LVVPGREFIRLGSLSKLSGKGLQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTI 812
Query: 88 DSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSGKTPSNEHAA 147
+ +DE + + ++ +S V A++ +E +W+ I + DL KS +P+ E A
Sbjct: 813 EESEDEWGVPHCLTLRGQRQSIIVAASSRSEMEKWVEDIQMAI-DLAEKS-SSPAPEFLA 870
Query: 148 VWVPDSEA 155
PD+++
Sbjct: 871 SSPPDNKS 878
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 61.6 bits (148), Expect = 6e-10
Identities = 31/92 (33%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Query: 124 NHINKCVTDLLSKSG---KTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGF 180
N +++C T++ S++ + W+PD A C C A F +R+HHCR CG
Sbjct: 1088 NCLSRCSTEIFSEASWEQVDKQDTEMTRWLPDHLAAHCYACDSA-FWLASRKHHCRNCGN 1146
Query: 181 VVCGPCSEKRFLLPSQS-SKPVRICDFCYDLL 211
V C C ++ +PSQ +P R+C CY L
Sbjct: 1147 VFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSL 1178
>gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 60.5 bits (145), Expect = 1e-09
Identities = 56/250 (22%), Positives = 95/250 (38%), Gaps = 51/250 (20%)
Query: 32 PGRVLIGEGVLTKLCRKK--PKARQFFLFNDILVY--GNIVIQKKKYNKQHIIPLENVTI 87
P LI EG + KL K P+ R FLFN +++Y + + +K++ + + + + +
Sbjct: 367 PANELIKEGQIQKLSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDISGLQV 426
Query: 88 DSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCV----------------- 130
I + + + ++I +S + T EK EW+ I +
Sbjct: 427 QDIV-KPNTAHTFIITGRKRSLELQTRTEEEKKEWIQIIQATIEKHKQNSETFKAFGGAF 485
Query: 131 ----------------TDLLSKSGKTPSNEHAAVWVP---------DSEATVCMRCQKAK 165
T + T + AA P D E C C +
Sbjct: 486 SQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAAGLEPRKLSSKTRRDKEKQSCKSCGETF 545
Query: 166 FTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDLLSAGDMATCQPARSD 225
+ RRHHC+ CG V+CG CSE +++S+ R+C C+ +T + +D
Sbjct: 546 NSITKRRHHCKLCGAVICGKCSE----FKAENSRQSRVCRDCFLTQPVAPESTEKTPTAD 601
Query: 226 SYSQSLKSPL 235
L PL
Sbjct: 602 PQPSLLCGPL 611
>gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 60.5 bits (145), Expect = 1e-09
Identities = 56/250 (22%), Positives = 95/250 (38%), Gaps = 51/250 (20%)
Query: 32 PGRVLIGEGVLTKLCRKK--PKARQFFLFNDILVY--GNIVIQKKKYNKQHIIPLENVTI 87
P LI EG + KL K P+ R FLFN +++Y + + +K++ + + + + +
Sbjct: 367 PANELIKEGQIQKLSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDISGLQV 426
Query: 88 DSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCV----------------- 130
I + + + ++I +S + T EK EW+ I +
Sbjct: 427 QDIV-KPNTAHTFIITGRKRSLELQTRTEEEKKEWIQIIQATIEKHKQNSETFKAFGGAF 485
Query: 131 ----------------TDLLSKSGKTPSNEHAAVWVP---------DSEATVCMRCQKAK 165
T + T + AA P D E C C +
Sbjct: 486 SQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAAGLEPRKLSSKTRRDKEKQSCKSCGETF 545
Query: 166 FTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDLLSAGDMATCQPARSD 225
+ RRHHC+ CG V+CG CSE +++S+ R+C C+ +T + +D
Sbjct: 546 NSITKRRHHCKLCGAVICGKCSE----FKAENSRQSRVCRDCFLTQPVAPESTEKTPTAD 601
Query: 226 SYSQSLKSPL 235
L PL
Sbjct: 602 PQPSLLCGPL 611
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 59.7 bits (143), Expect = 2e-09
Identities = 38/99 (38%), Positives = 50/99 (50%), Gaps = 10/99 (10%)
Query: 144 EHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQS-SKPVR 202
E A WV +A C RC + +F + R+HHCR CG + CG CS K +P K VR
Sbjct: 155 ERAPDWV---DAEECHRC-RVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVR 210
Query: 203 ICDFCYDLLS--AGDMATCQPARSDSYSQSLKSPLNDMS 239
+C+ CY+ L+ A AT Y L SPL+ S
Sbjct: 211 VCEPCYEQLNRKAEGKATSTTELPPEY---LTSPLSQQS 246
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 59.7 bits (143), Expect = 2e-09
Identities = 35/108 (32%), Positives = 49/108 (45%), Gaps = 12/108 (11%)
Query: 132 DLLSKSGKTPSNE---HAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSE 188
D LS++ P ++ WVPD A+ C C +F RRHHCR CG V C C
Sbjct: 1091 DCLSEASWEPVDKKETEVTRWVPDHMASHCYNCD-CEFWLAKRRHHCRNCGNVFCAGCCH 1149
Query: 189 KRFLLPSQS-SKPVRICDFCYDLLSAGDMATCQPARSDSYSQSLKSPL 235
+ +P Q PV +C+ CY+ + + SQ LK P+
Sbjct: 1150 LKLPIPDQQLYDPVLVCNSCYEHIQVS-------RARELMSQQLKKPI 1190
>gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo
sapiens]
Length = 1054
Score = 59.7 bits (143), Expect = 2e-09
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
Query: 29 LTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVY-GNIVIQKKKYNKQHIIPLENVTI 87
L PGR I EG L KL +K + R FFLF+D+L+Y V + + ++PL+ + +
Sbjct: 749 LIAPGREFIREGCLHKLTKKGLQQRMFFLFSDMLLYTSKGVAGTSHFRIRGLLPLQGMLV 808
Query: 88 DSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSGKTPS 142
+ +E + + + I K+ V A+T EK +WM +N + S P+
Sbjct: 809 EESDNEWSVPHCFTIYAAQKTIVVAASTRLEKEKWMLDLNSAIQAAKSGGDTAPA 863
>gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens]
Length = 410
Score = 59.7 bits (143), Expect = 2e-09
Identities = 32/85 (37%), Positives = 42/85 (49%), Gaps = 14/85 (16%)
Query: 142 SNEHAAVWVPDSEATVCMRCQKAKFTPVN----------RRHHCRKCGFVVCGPCSEKRF 191
S E A W+ E+ C +C++ F + R+HHCRKCG VCG CS KR
Sbjct: 274 SREEAPQWL---ESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQAVCGKCSSKRS 330
Query: 192 LLPSQSSK-PVRICDFCYDLLSAGD 215
P + VR+CD CYD + D
Sbjct: 331 SYPVMGFEFQVRVCDSCYDSIKDED 355
>gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform 1
[Homo sapiens]
Length = 1170
Score = 58.9 bits (141), Expect = 4e-09
Identities = 25/68 (36%), Positives = 41/68 (60%), Gaps = 2/68 (2%)
Query: 151 PDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRF-LLPSQSSKPVRICDFCYD 209
P + + C C A+F R+HHCR CG ++C CS K ++ +KPVR+C+ C+D
Sbjct: 1104 PWCDGSYCYECT-ARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFD 1162
Query: 210 LLSAGDMA 217
+L+ G ++
Sbjct: 1163 VLTLGGVS 1170
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 58.5 bits (140), Expect = 5e-09
Identities = 27/64 (42%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Query: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQS-SKPVRICDFC 207
W+PD A C C A F +R+HHCR CG V C C ++ +PSQ +P R+C C
Sbjct: 1079 WLPDHLAAHCYACDSA-FWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSC 1137
Query: 208 YDLL 211
Y L
Sbjct: 1138 YSSL 1141
>gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Homo
sapiens]
Length = 362
Score = 55.5 bits (132), Expect = 4e-08
Identities = 31/85 (36%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Query: 124 NHINKCVTDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVC 183
N + VT + G A WVPD E C C+K +F+ +HHCR CG C
Sbjct: 272 NTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRK-EFSIKLSKHHCRACGQGFC 330
Query: 184 GPCSEKRFLLPSQS-SKPVRICDFC 207
CS R +PS+ PVR+C C
Sbjct: 331 DECSHDRRAVPSRGWDHPVRVCFNC 355
Score = 53.5 bits (127), Expect = 2e-07
Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 147 AVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQ--SSKPVRIC 204
A W P+S+ C +C + F + +HHCR CG C CS K +P + PVR+C
Sbjct: 178 AYWRPNSQILSCNKCATS-FKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVC 236
Query: 205 DFCYD 209
D CY+
Sbjct: 237 DNCYE 241
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,999,980
Number of Sequences: 37866
Number of extensions: 451071
Number of successful extensions: 2036
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 1897
Number of HSP's gapped (non-prelim): 123
length of query: 249
length of database: 18,247,518
effective HSP length: 100
effective length of query: 149
effective length of database: 14,460,918
effective search space: 2154676782
effective search space used: 2154676782
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.