Guide to the Human Genome
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Search of human proteins with 47679080

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47679080 zinc finger and BTB domain containing 46 [Homo
sapiens]
         (589 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47679080 zinc finger and BTB domain containing 46 [Homo sapiens]  1195   0.0  
gi|157694499 zinc finger and BTB domain containing 10 isoform a ...   284   2e-76
gi|224591419 zinc finger and BTB domain containing 8B [Homo sapi...   214   2e-55
gi|157694497 zinc finger and BTB domain containing 10 isoform b ...   159   7e-39
gi|167234429 zinc finger and BTB domain containing 17 [Homo sapi...   154   2e-37
gi|94721342 zinc finger and BTB domain containing 8A [Homo sapiens]   144   3e-34
gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens]          130   3e-30
gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens]          129   8e-30
gi|109134351 zinc finger and BTB domain containing 44 [Homo sapi...   112   7e-25
gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]    105   1e-22
gi|223972645 zinc finger protein 509 [Homo sapiens]                   105   2e-22
gi|139394599 hypermethylated in cancer 2 [Homo sapiens]               102   1e-21
gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens]     94   3e-19
gi|209413766 zinc finger and BTB domain containing 43 [Homo sapi...    92   1e-18
gi|7662100 zinc finger and BTB domain containing 43 [Homo sapiens]     92   1e-18
gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens]      92   1e-18
gi|8923885 myoneurin [Homo sapiens]                                    86   7e-17
gi|13540490 BTB and CNC homology 1, basic leucine zipper transcr...    85   2e-16
gi|45827690 BTB and CNC homology 1 transcription factor isoform ...    85   2e-16
gi|4502353 BTB and CNC homology 1 transcription factor isoform a...    85   2e-16
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]    83   8e-16
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...    82   2e-15
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...    82   2e-15
gi|212286156 zinc finger and BTB domain containing 42 [Homo sapi...    82   2e-15
gi|8922854 kelch-like 26 [Homo sapiens]                                82   2e-15
gi|38044286 zinc finger protein 547 [Homo sapiens]                     81   2e-15
gi|32469511 B-cell CLL/lymphoma 6, member B (zinc finger protein...    81   3e-15
gi|21040324 B-cell lymphoma 6 protein isoform 1 [Homo sapiens]         80   4e-15
gi|197927147 B-cell lymphoma 6 protein isoform 2 [Homo sapiens]        80   4e-15
gi|195927002 B-cell lymphoma 6 protein isoform 1 [Homo sapiens]        80   4e-15

>gi|47679080 zinc finger and BTB domain containing 46 [Homo sapiens]
          Length = 589

 Score = 1195 bits (3092), Expect = 0.0
 Identities = 589/589 (100%), Positives = 589/589 (100%)

Query: 1   MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLY 60
           MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLY
Sbjct: 1   MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLY 60

Query: 61  CQVQKTSEQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQA 120
           CQVQKTSEQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQA
Sbjct: 61  CQVQKTSEQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQA 120

Query: 121 CHDFIKAALDISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPADS 180
           CHDFIKAALDISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPADS
Sbjct: 121 CHDFIKAALDISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPADS 180

Query: 181 SGDSAIASCHDGGSSYGKEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGG 240
           SGDSAIASCHDGGSSYGKEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGG
Sbjct: 181 SGDSAIASCHDGGSSYGKEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGG 240

Query: 241 SELPSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFL 300
           SELPSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFL
Sbjct: 241 SELPSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFL 300

Query: 301 PTSGWPFSSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEASYLGPPLTPEKDDA 360
           PTSGWPFSSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEASYLGPPLTPEKDDA
Sbjct: 301 PTSGWPFSSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEASYLGPPLTPEKDDA 360

Query: 361 LHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKC 420
           LHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKC
Sbjct: 361 LHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKC 420

Query: 421 PYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCS 480
           PYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCS
Sbjct: 421 PYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCS 480

Query: 481 RVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYLEDPED 540
           RVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYLEDPED
Sbjct: 481 RVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYLEDPED 540

Query: 541 PRGEAEELGEDDEGLAPEDALLADDKDEEDSPRPRSPPGGPDKDFAWLS 589
           PRGEAEELGEDDEGLAPEDALLADDKDEEDSPRPRSPPGGPDKDFAWLS
Sbjct: 541 PRGEAEELGEDDEGLAPEDALLADDKDEEDSPRPRSPPGGPDKDFAWLS 589


>gi|157694499 zinc finger and BTB domain containing 10 isoform a
           [Homo sapiens]
          Length = 871

 Score =  284 bits (726), Expect = 2e-76
 Identities = 203/575 (35%), Positives = 276/575 (48%), Gaps = 77/575 (13%)

Query: 12  SHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS-EQA 70
           S+   LLR+LNEQR+ G+LCDV +VV GK+FKAHKN+L+  SR+FKTLYC   K S  Q 
Sbjct: 345 SYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQN 404

Query: 71  TVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALD 130
             THLDI   QGF  I+DF+YS +L LTS+N IEVM+ AS+LQM+++VQ C +FIK AL+
Sbjct: 405 NTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALN 464

Query: 131 ISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPADSSGDSAIASCH 190
           ISIKS+A + +   +       + + L S+    +  S W  R  +   S+       C+
Sbjct: 465 ISIKSEAPESVV-VDYNNRKPVNRDGL-SSSRDQKIASFWATRNLTNLASNVKIENDGCN 522

Query: 191 -DGG--SSYGKEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAK 247
            D G   +Y   D     DG  +++                                +  
Sbjct: 523 VDEGQIENYQMNDSSWVQDGSPEMAE-------------------------------NES 551

Query: 248 DGAVQNSFSEQSAGDAWQPTG--RRKNRKNKETVRHITQQVE---DDSRASSPVPSFLPT 302
           +G  +            Q TG  RRKN+  K  + +I    E   +D     P P   P 
Sbjct: 552 EGQTKVFIWNNMGSQGIQETGKTRRKNQTTKRFIYNIPPNNETNLEDCSVMQP-PVAYPE 610

Query: 303 SGWPFSSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEAS-----YLGPPLTPEK 357
                   + + D ++      D R   A L A+      GG+A        G    P  
Sbjct: 611 ENTLLIKEEPDLDGALLSGPDGD-RNVNANLLAEAGTSQDGGDAGTSHDFKYGLMPGPSN 669

Query: 358 DDALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKK 417
           D         +N     +   +    K  +L +      E    G  SL +N       K
Sbjct: 670 DFKYGLIPGTSNDFKYGLIPGASNDFKYGLLPESWPKQ-ETWENGESSLIMN-------K 721

Query: 418 FKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCK 477
            KCP+CS+ A ++  LKRH+  HTG R + C+ICGK FTRREH+KRH+LVH KDKKY C 
Sbjct: 722 LKCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHSLVHKKDKKYKCM 781

Query: 478 VCSRVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYLED 537
           VC ++FM AASVGIRHGSRR+GVC DCA +          GG EG  +      G   E 
Sbjct: 782 VCKKIFMLAASVGIRHGSRRYGVCVDCADKSQP-------GGQEGVDQ------GQDTEF 828

Query: 538 PEDPRGEAEELGEDDEGLAPEDALLADDKDEEDSP 572
           P D   E  E+GE DE        L DD ++++ P
Sbjct: 829 PRDEEYEENEVGEADEE-------LVDDGEDQNDP 856


>gi|224591419 zinc finger and BTB domain containing 8B [Homo
           sapiens]
          Length = 495

 Score =  214 bits (545), Expect = 2e-55
 Identities = 164/521 (31%), Positives = 237/521 (45%), Gaps = 121/521 (23%)

Query: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
           ME+ S+Y  LL ELNEQR+    CD  ++VEG++FKAH+N+L  +S YF+ L     + S
Sbjct: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60

Query: 68  EQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKA 127
            + +   LDIVT+  F  I+DF+YS  L L   NVIEVMSAAS+LQM D+V  C  +I++
Sbjct: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRS 120

Query: 128 ALDISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPADSSGDSAIA 187
           +LDI  K +                  EA ++A +A            + A ++  +A A
Sbjct: 121 SLDICRKMEK-----------------EAAVAAAVA------------AAAAAAAAAAAA 151

Query: 188 SCHDGGSSYGKEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAK 247
           + H   S      +E  + G   + S P        G   ++  + SP    G   P   
Sbjct: 152 AAHQVDSESPSSGREGTSCGTKSLVSSP------AEGEKSVECLRESPCGDCGDCHPL-- 203

Query: 248 DGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFLPTSGWPF 307
           +  V++S    SA                            DS  S+P     P     F
Sbjct: 204 ELVVRDSLGGGSA----------------------------DSNLSTPPKRIEPKV--EF 233

Query: 308 SSRDSNADLSVTEASSSDSRGERAELYA------QVEEGLLGGEA--------------- 346
            + +   D+           GE+ + YA       VEE L  G+A               
Sbjct: 234 DADEVEVDV-----------GEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLE 282

Query: 347 SYLGPPLTPEKDDALHQATAVANLR--AALMSKNSLLSLKADVLGDDGSLLFEYLPRGAH 404
           + L     P KDDA H  +     R   A ++ +S++ ++AD  G+D             
Sbjct: 283 ALLRNSAAPSKDDADHHFSRSLEGRPEGAGVAMSSMMDVQADWYGEDSG----------- 331

Query: 405 SLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRH 464
               +   V  K  KCP+C ++A  + ILKRH+RSHTGERPYPCE CGK+FTR+EH++ H
Sbjct: 332 ----DVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSH 387

Query: 465 TL-VHSKDKKYVCKVCSRVFMSAASVGIRHGSRRHGVCTDC 504
            L VH  ++  +CK C R F S  S G+    RR G+C  C
Sbjct: 388 ALSVHRSNRPIICKGCRRTFTSHLSQGL----RRFGLCDSC 424


>gi|157694497 zinc finger and BTB domain containing 10 isoform b
           [Homo sapiens]
          Length = 847

 Score =  159 bits (402), Expect = 7e-39
 Identities = 77/131 (58%), Positives = 100/131 (76%), Gaps = 1/131 (0%)

Query: 12  SHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS-EQA 70
           S+   LLR+LNEQR+ G+LCDV +VV GK+FKAHKN+L+  SR+FKTLYC   K S  Q 
Sbjct: 345 SYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQN 404

Query: 71  TVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALD 130
             THLDI   QGF  I+DF+YS +L LTS+N IEVM+ AS+LQM+++VQ C +FIK AL+
Sbjct: 405 NTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALN 464

Query: 131 ISIKSDASDEL 141
           ISIKS+A + +
Sbjct: 465 ISIKSEAPESV 475



 Score =  155 bits (393), Expect = 7e-38
 Identities = 80/163 (49%), Positives = 101/163 (61%), Gaps = 20/163 (12%)

Query: 410 EFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHS 469
           E ++I  K KCP+CS+ A ++  LKRH+  HTG R + C+ICGK FTRREH+KRH+LVH 
Sbjct: 690 ESSLIMNKLKCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHSLVHK 749

Query: 470 KDKKYVCKVCSRVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFP 529
           KDKKY C VC ++FM AASVGIRHGSRR+GVC DCA +          GG EG  +    
Sbjct: 750 KDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCADKSQP-------GGQEGVDQ---- 798

Query: 530 GDGPYLEDPEDPRGEAEELGEDDEGLAPEDALLADDKDEEDSP 572
             G   E P D   E  E+GE DE        L DD ++++ P
Sbjct: 799 --GQDTEFPRDEEYEENEVGEADEE-------LVDDGEDQNDP 832


>gi|167234429 zinc finger and BTB domain containing 17 [Homo
           sapiens]
          Length = 803

 Score =  154 bits (390), Expect = 2e-37
 Identities = 130/481 (27%), Positives = 197/481 (40%), Gaps = 49/481 (10%)

Query: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
           M+   H +H+L +LN+QRQ G+LCD   VV+G  FKAHK VL   S YFK L+       
Sbjct: 1   MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFV------ 54

Query: 68  EQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKA 127
           +Q  V HLDI  A G   +++FMY+A L+L+  NV +V++ A+FLQM DI+ ACH     
Sbjct: 55  DQKDVVHLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITACHALKSL 114

Query: 128 ALDISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPADSSGDSAIA 187
           A   +     ++ LA    G    +  E + ++ ++        A R++P   S D    
Sbjct: 115 AEPATSPGGNAEALA--TEGGDKRAKEEKVATSTLSRLE----QAGRSTPIGPSRDLKEE 168

Query: 188 SCHDGGSSYGKEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAK 247
                 S+    +Q  KAD P +     L P           E  +S S     E+  A+
Sbjct: 169 RGGQAQSAASGAEQTEKADAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPAR 228

Query: 248 DGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFLPTSGWPF 307
            G  +    E+   +   P   ++     E      +   ++S                 
Sbjct: 229 KGEEEQKEQEEQEEEGAGPAEVKEEGSQLENGEAPEENENEES----------------- 271

Query: 308 SSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEASYLGPPLTPEKDDALHQATAV 367
           +  DS  +L       S++RG R+  Y    E    G   +       + +D   + T  
Sbjct: 272 AGTDSGQEL------GSEARGLRSGTYGDRTESKAYGSVIH-------KCEDCGKEFTHT 318

Query: 368 ANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKCPYCSFSA 427
            N +  +         K     +      +     AH  + +      K + C  C  S 
Sbjct: 319 GNFKRHIRIHT---GEKPFSCRECSKAFSDPAACKAHEKTHSPL----KPYGCEECGKSY 371

Query: 428 MHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAA 487
               +L  H + H+GE  Y CE CGK FT   ++KRH LVHS +K Y C  C R F    
Sbjct: 372 RLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPT 431

Query: 488 S 488
           S
Sbjct: 432 S 432



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 4/96 (4%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K  +C  C  +      L  H+R HTGE+PY CE CGK+F +   +  H   H   + + 
Sbjct: 528 KPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHK 587

Query: 476 CKVCSRVFMSAASVG---IRHGSRRHGVCTDCAGRG 508
           C VCS+ F++   +    I H   +  +C  C GRG
Sbjct: 588 CSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKC-GRG 622



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 3/93 (3%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K + C +C         L+RH+R HTGE+P  C +CGK FT+   +  H   H+ +K YV
Sbjct: 500 KPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYV 559

Query: 476 CKVCSRVFMSAASVG--IRHGSR-RHGVCTDCA 505
           C+ C + F+ ++ +   IRH    R   C+ C+
Sbjct: 560 CERCGKRFVQSSQLANHIRHHDNIRPHKCSVCS 592



 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 3/92 (3%)

Query: 419 KCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKV 478
           KC  C         LKRH+R H+GE+PY C  C ++F     ++RH  +H+ +K   C +
Sbjct: 475 KCRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVM 534

Query: 479 CSRVFMSAASVGI---RHGSRRHGVCTDCAGR 507
           C + F  A+S+     +H   +  VC  C  R
Sbjct: 535 CGKAFTQASSLIAHVRQHTGEKPYVCERCGKR 566



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 21/68 (30%), Positives = 33/68 (48%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K + C  C    +    L  H+R H   RP+ C +C K F     + +H ++H+ +K Y+
Sbjct: 556 KPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYL 615

Query: 476 CKVCSRVF 483
           C  C R F
Sbjct: 616 CDKCGRGF 623



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 18/46 (39%), Positives = 30/46 (65%)

Query: 419 KCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRH 464
           KC  CS + ++   L +H+  HTGE+PY C+ CG+ F R ++++ H
Sbjct: 587 KCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSH 632


>gi|94721342 zinc finger and BTB domain containing 8A [Homo sapiens]
          Length = 441

 Score =  144 bits (362), Expect = 3e-34
 Identities = 72/127 (56%), Positives = 89/127 (70%)

Query: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
           MEI+SH  HLL++LNEQR+  V CD  ++VEGKVFKAH+NVL  SS YFK L  Q  K +
Sbjct: 1   MEISSHQSHLLQQLNEQRRQDVFCDCSILVEGKVFKAHRNVLFASSGYFKMLLSQNSKET 60

Query: 68  EQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKA 127
            Q T       +   F  I+DF+YS  L+LT +NVIEVMSAASFLQMTD++  C  FIK+
Sbjct: 61  SQPTTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASFLQMTDVISVCKTFIKS 120

Query: 128 ALDISIK 134
           +LDIS K
Sbjct: 121 SLDISEK 127



 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 56/163 (34%), Positives = 82/163 (50%), Gaps = 16/163 (9%)

Query: 415 RKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKY 474
           R +FKCPYC+     +  LKRH+R HTGERPYPC+ CGK+F+R +H+  H     +  K 
Sbjct: 279 RMRFKCPYCTHVVKRKADLKRHLRCHTGERPYPCQACGKRFSRLDHLSSHFRTIHQACKL 338

Query: 475 VCKVCSRVFMSAASVGIRHGSRRHGVCTDC-AGRGMAG-PLDHGGGGGEGSPEALFPGDG 532
           +C+ C R         ++ G+RR+ +C +C A  G+   P+D      E     + P DG
Sbjct: 339 ICRKCKRHVTDLTGQVVQEGTRRYRLCNECLAEFGIDSLPIDL-----EAEQHLMSPSDG 393

Query: 533 ---PYLEDPEDPRGEAEELGEDDEGLAPEDALL--ADDKDEED 570
                    ED      E+ ED  G    D ++   DD +EE+
Sbjct: 394 DKDSRWHLSEDENRSYVEIVEDGSG----DLVIQQVDDSEEEE 432


>gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens]
          Length = 531

 Score =  130 bits (327), Expect = 3e-30
 Identities = 138/544 (25%), Positives = 219/544 (40%), Gaps = 102/544 (18%)

Query: 5   KEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQ 64
           ++ ME   H RHLL+ L+EQR  G LCD  V+V    F+AH+ VL   S YF   Y   +
Sbjct: 7   EDSMEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFY---K 63

Query: 65  KTSEQATVTHL--DIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACH 122
              ++  + HL  DIVTA  F  +++FMY   L      + +V++AAS+L M DIV+ C 
Sbjct: 64  DQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCK 123

Query: 123 DFIKAALDISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPADSSG 182
             +K        S   +E A     +S S   E+L                      S G
Sbjct: 124 KKLKEKATTEADSTKKEEDA-----SSCSDKVESL----------------------SDG 156

Query: 183 DSAIASCHDGGSSYGKEDQEPKADGPDDVSSQP--LWPGDVGYGPLRIKEEQVSPSQYGG 240
            S IA         G++++        D++++P  +W        +R+  +     Q GG
Sbjct: 157 SSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEPGNMW--------MRLPSDSAGIPQAGG 208

Query: 241 SELPSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFL 300
              P A            +AG             ++ +V  +    + D      V S L
Sbjct: 209 EAEPHA-----------TAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSL 257

Query: 301 P----TSGWPFSSRD---SN-ADLSVTEASSSDSRGERAELY----AQVEEGL-LGGEAS 347
                 +   FSS+D   SN   + V + +S D        Y    + V+E +       
Sbjct: 258 SGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQ 317

Query: 348 YLGPPLTPEKDDAL--------------HQATAVANLRAALMSKNSLLSLKADVLGDDGS 393
           Y    L P ++D++                      ++     ++SLL   +++L   G 
Sbjct: 318 YEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQ 377

Query: 394 L----LFEYLPRGAHSLSLNEFTVIRKK----------FKCPYCS-----FSAMHQCILK 434
           +    L   +    H L ++  T  R++             P CS     FS M+   LK
Sbjct: 378 IFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMY--TLK 435

Query: 435 RHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIRHG 494
           RH R+H+GE+PY C  CGK F    ++ RH +VH+++K + CK C R F  +  +  RH 
Sbjct: 436 RHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDL-YRHI 494

Query: 495 SRRH 498
            + H
Sbjct: 495 RKFH 498



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 19/76 (25%), Positives = 39/76 (51%), Gaps = 6/76 (7%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K + C  C  S  +   L RH   HT E+P+ C+ C ++FT+   + RH       +K+ 
Sbjct: 445 KPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHI------RKFH 498

Query: 476 CKVCSRVFMSAASVGI 491
           C++ + + + + ++ +
Sbjct: 499 CELVNSLSVKSEALSL 514


>gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens]
          Length = 522

 Score =  129 bits (324), Expect = 8e-30
 Identities = 138/541 (25%), Positives = 217/541 (40%), Gaps = 102/541 (18%)

Query: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
           ME   H RHLL+ L+EQR  G LCD  V+V    F+AH+ VL   S YF   Y   +   
Sbjct: 1   MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFY---KDQL 57

Query: 68  EQATVTHL--DIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFI 125
           ++  + HL  DIVTA  F  +++FMY   L      + +V++AAS+L M DIV+ C   +
Sbjct: 58  DKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKL 117

Query: 126 KAALDISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPADSSGDSA 185
           K        S   +E A     +S S   E+L                      S G S 
Sbjct: 118 KEKATTEADSTKKEEDA-----SSCSDKVESL----------------------SDGSSH 150

Query: 186 IASCHDGGSSYGKEDQEPKADGPDDVSSQP--LWPGDVGYGPLRIKEEQVSPSQYGGSEL 243
           IA         G++++        D++++P  +W        +R+  +     Q GG   
Sbjct: 151 IAGDLPSDEDEGEDEKLNILPSKRDLAAEPGNMW--------MRLPSDSAGIPQAGGEAE 202

Query: 244 PSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFLP-- 301
           P A            +AG             ++ +V  +    + D      V S L   
Sbjct: 203 PHA-----------TAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGV 251

Query: 302 --TSGWPFSSRD---SN-ADLSVTEASSSDSRGERAELY----AQVEEGL-LGGEASYLG 350
              +   FSS+D   SN   + V + +S D        Y    + V+E +       Y  
Sbjct: 252 ENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEP 311

Query: 351 PPLTPEKDDAL--------------HQATAVANLRAALMSKNSLLSLKADVLGDDGSL-- 394
             L P ++D++                      ++     ++SLL   +++L   G +  
Sbjct: 312 AHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFM 371

Query: 395 --LFEYLPRGAHSLSLNEFTVIRKK----------FKCPYCS-----FSAMHQCILKRHM 437
             L   +    H L ++  T  R++             P CS     FS M+   LKRH 
Sbjct: 372 CPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMY--TLKRHE 429

Query: 438 RSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIRHGSRR 497
           R+H+GE+PY C  CGK F    ++ RH +VH+++K + CK C R F  +  +  RH  + 
Sbjct: 430 RTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDL-YRHIRKF 488

Query: 498 H 498
           H
Sbjct: 489 H 489



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 19/76 (25%), Positives = 39/76 (51%), Gaps = 6/76 (7%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K + C  C  S  +   L RH   HT E+P+ C+ C ++FT+   + RH       +K+ 
Sbjct: 436 KPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHI------RKFH 489

Query: 476 CKVCSRVFMSAASVGI 491
           C++ + + + + ++ +
Sbjct: 490 CELVNSLSVKSEALSL 505


>gi|109134351 zinc finger and BTB domain containing 44 [Homo
           sapiens]
          Length = 453

 Score =  112 bits (281), Expect = 7e-25
 Identities = 119/485 (24%), Positives = 198/485 (40%), Gaps = 73/485 (15%)

Query: 11  TSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQA 70
           +SH + +L +LN  R  G  CD+ + V+ K+F+AHK VL   S +F+T     Q   E  
Sbjct: 11  SSHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVG-QAEDENK 69

Query: 71  TVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALD 130
            V  L  VT  GF  ++++ Y+A L++ + N+I+V++AAS++QM  +   C +F+K++  
Sbjct: 70  NVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSS-- 127

Query: 131 ISIKSDASDELAEFEIGASSSS-----STEALISAVMAGRSI----------------SP 169
           I   +  S      + G  ++S     S +  IS V +  S+                S 
Sbjct: 128 ILWNTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRKRKSY 187

Query: 170 WLARRTSPADSSGDSAIASCHDGGSSYGKEDQEPKADGPDDVSSQPLWPGDVGYG-PLRI 228
            +    SP      ++     +  +SY +   +P       V S   +P    +G   RI
Sbjct: 188 IVMSPESPVKCGTQTSSPQVLNSSASYSENRNQP-------VDSSLAFPWTFPFGIDRRI 240

Query: 229 KEEQVSPSQYGGS-ELPS-AKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQV 286
           + E+V  ++   + ELP  ++ G     +    +     P G  ++ + K       +  
Sbjct: 241 QPEKVKQAENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVERLSDEEVH 300

Query: 287 EDDSRASSPVPSFLPTSGWPFSSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEA 346
           E+ S+  S   S L        S     DL ++  SSS            V+EG+  G  
Sbjct: 301 EEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSS---------IGSVDEGVSEGLP 351

Query: 347 SYLGPPLT---PEKDDALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGA 403
           +      T   P+ DD L        L  A  + +   + +    G D            
Sbjct: 352 TLQSTSSTNAPPDDDDRLENVQYPYQLYIAPSTSS---TERPSPNGPD------------ 396

Query: 404 HSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKR 463
                       + F+CP C         LK+HM  H+G +P+ C+ CGKKFTR   +K 
Sbjct: 397 ------------RPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKM 444

Query: 464 HTLVH 468
           H L H
Sbjct: 445 HRLKH 449



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 19/47 (40%), Positives = 30/47 (63%)

Query: 443 ERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASV 489
           +RP+ C  CG +FTR +++K+H L+HS  K + C  C + F  A S+
Sbjct: 396 DRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSL 442


>gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]
          Length = 574

 Score =  105 bits (262), Expect = 1e-22
 Identities = 122/507 (24%), Positives = 194/507 (38%), Gaps = 74/507 (14%)

Query: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
           ME   H + LL+ L EQR  G LCD  V+V    F AH+ VL   S +F+  Y + +   
Sbjct: 51  MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110

Query: 68  EQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIE-VMSAASFLQMTDIVQACHDFIK 126
                 H +IVTA  F  ++DFMY+  L L     +E V++AAS+L M DIV+ C   ++
Sbjct: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170

Query: 127 A-----ALDISIKSDASDELAEFEIGASSSSSTE-ALISAVMAGR----------SISPW 170
           A     A     + + + +L   E  +S+S  T+ +L SA  +G           + SP 
Sbjct: 171 ARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPT 230

Query: 171 LARRTSPADSSGDSAIASCHDGGSSYGKEDQEPKAD--------------------GPDD 210
           +     P  SSG        +  + + +    P AD                    G   
Sbjct: 231 VRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFSSGISA 290

Query: 211 VSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAKDGAVQNSFSEQSAGDAWQPTGRR 270
           VS +PL   DVG   LR+ E +       G   P++   +     S      A  P    
Sbjct: 291 VSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAPAPAEAE 350

Query: 271 KNRKNKETVRHITQQVE-DDSRASSPVPSFLPTSGWPFSSRDSNADLSVTEASSSDSRGE 329
             +   E +    ++ +  D +   P  +F P+ G  + ++ S  +      ++      
Sbjct: 351 LVQVKVEAIVISDEETDVSDEQPQGPERAF-PSGGAVYGAQPSQPEAFEDPGAAGLEEVG 409

Query: 330 RAELYAQVEE----GLLGGEASYLGPPLTPEKDDALHQATAVANLRAALMSKNSLLSLKA 385
            ++ +   +      LL G   Y             H+    + L A   S +  L L +
Sbjct: 410 PSDHFLPTDPHLPYHLLPGAGQY-------------HRGLVTSPLPAP-ASLHEPLYLSS 455

Query: 386 DVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERP 445
           +     GS        G  +  +       K F C Y          L+RH   HT ERP
Sbjct: 456 EYEAAPGSF-------GVFTEDVPTCKTCGKTFSCSY---------TLRRHATVHTRERP 499

Query: 446 YPCEICGKKFTRREHMKRH-TLVHSKD 471
           Y C  C + +T+   + RH    H++D
Sbjct: 500 YECRYCLRSYTQSGDLYRHIRKAHNED 526


>gi|223972645 zinc finger protein 509 [Homo sapiens]
          Length = 765

 Score =  105 bits (261), Expect = 2e-22
 Identities = 50/119 (42%), Positives = 78/119 (65%), Gaps = 2/119 (1%)

Query: 10  ITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQ 69
           + +H  HLL++L+EQR  G+LCD  +VV+G  FKAHKNVL   S+YF++L+     +S++
Sbjct: 4   VATHSCHLLQQLHEQRIQGLLCDCMLVVKGVCFKAHKNVLAAFSQYFRSLF--QNSSSQK 61

Query: 70  ATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAA 128
             V HLD+    G   I+DFMY++HL L   N+  ++  A  LQ+ +++  CH F+K+A
Sbjct: 62  NDVFHLDVKNVSGIGQILDFMYTSHLDLNQDNIQVMLDTAQCLQVQNVLSLCHTFLKSA 120



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 34/99 (34%), Positives = 56/99 (56%), Gaps = 4/99 (4%)

Query: 415 RKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKY 474
           ++++ C  C     H   L+ H RSHTGE+P+ C ICGK F++  +++ H   HS +K Y
Sbjct: 392 QRQYACELCGKPFKHPSNLELHKRSHTGEKPFECNICGKHFSQAGNLQTHLRRHSGEKPY 451

Query: 475 VCKVCSRVFMSAASVG---IRHGSRRHGVCTDCAGRGMA 510
           +C++C + F ++  V    I H   +  +C D  GRG +
Sbjct: 452 ICEICGKRFAASGDVQRHIIIHSGEKPHLC-DICGRGFS 489



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 3/92 (3%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K F+C  C         L+ H+R H+GE+PY CEICGK+F     ++RH ++HS +K ++
Sbjct: 421 KPFECNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASGDVQRHIIIHSGEKPHL 480

Query: 476 CKVCSRVFMSAASVGIR---HGSRRHGVCTDC 504
           C +C R F + +++      H + +   C +C
Sbjct: 481 CDICGRGFSNFSNLKEHKKTHTADKVFTCDEC 512



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 29/72 (40%), Positives = 39/72 (54%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K F C  C  S   Q  L +H   HTGERPY C  CGK F     ++RH   H+ +K Y 
Sbjct: 505 KVFTCDECGKSFNMQRKLVKHRIRHTGERPYSCSACGKCFGGSGDLRRHVRTHTGEKPYT 564

Query: 476 CKVCSRVFMSAA 487
           C++C++ F  +A
Sbjct: 565 CEICNKCFTRSA 576



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 3/92 (3%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K + C  C         ++RH+  H+GE+P+ C+ICG+ F+   ++K H   H+ DK + 
Sbjct: 449 KPYICEICGKRFAASGDVQRHIIIHSGEKPHLCDICGRGFSNFSNLKEHKKTHTADKVFT 508

Query: 476 CKVCSRVFMSAASV---GIRHGSRRHGVCTDC 504
           C  C + F     +    IRH   R   C+ C
Sbjct: 509 CDECGKSFNMQRKLVKHRIRHTGERPYSCSAC 540



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 30/62 (48%), Positives = 39/62 (62%), Gaps = 6/62 (9%)

Query: 414 IRKKFKCPYCSFSAMHQCI-----LKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVH 468
           IR   + PY S SA  +C      L+RH+R+HTGE+PY CEIC K FTR   ++RH  +H
Sbjct: 527 IRHTGERPY-SCSACGKCFGGSGDLRRHVRTHTGEKPYTCEICNKCFTRSAVLRRHKKMH 585

Query: 469 SK 470
            K
Sbjct: 586 CK 587



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 2/83 (2%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K   C  C     +   LK H ++HT ++ + C+ CGK F  +  + +H + H+ ++ Y 
Sbjct: 477 KPHLCDICGRGFSNFSNLKEHKKTHTADKVFTCDECGKSFNMQRKLVKHRIRHTGERPYS 536

Query: 476 CKVCSRVFMSAASVGIRHGSRRH 498
           C  C + F    S  +R   R H
Sbjct: 537 CSACGKCF--GGSGDLRRHVRTH 557


>gi|139394599 hypermethylated in cancer 2 [Homo sapiens]
          Length = 615

 Score =  102 bits (254), Expect = 1e-21
 Identities = 141/604 (23%), Positives = 225/604 (37%), Gaps = 159/604 (26%)

Query: 7   DMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKT 66
           DME+ SH + LL +LN+QR  G LCDV ++VE  +F+AHKNVL  SS YFK+L       
Sbjct: 22  DMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLH---- 77

Query: 67  SEQATVTHLDIVTAQGFKAIIDFMYSAHLALTSR----NVIEVMSAASFLQMTDIVQACH 122
            +       D+V++  F+ I+DF+Y+  L  + +    N   +++AAS+LQ+ ++   C 
Sbjct: 78  -DNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLLTAASYLQLPELAALCR 136

Query: 123 DFIKAA------------------------------------LDISIKSDASDELA---- 142
             +K A                                    +D    + A  EL     
Sbjct: 137 RKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYQGLVDGRKGAHAPQELPQAKG 196

Query: 143 ---EFEIGASSSSSTEALISAVMAGRSISPWLARRTSPADSSGDSAIASCHD--GGSSYG 197
              E  +G S+  S + L      GR++ P          + G++ +  C     GSS G
Sbjct: 197 SDDELFLGGSNQDSVQGL------GRAVCP----------AGGEAGLGGCSSSTNGSSGG 240

Query: 198 KEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAKDGAVQNSFSE 257
            E QE   D      S PL P   G         Q+S SQ+G     SA   A   S+SE
Sbjct: 241 CE-QELGLD--LSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSE 297

Query: 258 -----------QSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFLPTSGWP 306
                      + A D           + ++++RH T++ E   +         P +G P
Sbjct: 298 LGGTPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKE--------PVAGSP 349

Query: 307 FSSRDSNADLSVTEASSSDSRGERAE-LYAQVEEGLLGGEASYLGP---PLTPEKDDALH 362
           F  R++               GE  E +  +V  G+L   A   GP   P  P K++  +
Sbjct: 350 FERREA--------GPKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEEN 401

Query: 363 QATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKCPY 422
              A         S++S  S      G   S  + Y   G  ++S  +       + C  
Sbjct: 402 GKDA---------SEDSAQSGSEGGSG-HASAHYMYRQEGYETVSYGD-----NLYVCIP 446

Query: 423 CSFSAMHQCILKRHMRSHTGE-----------------------------------RPYP 447
           C+        L  H+ +HT E                                   RP+ 
Sbjct: 447 CAKGFPSSEQLNAHVETHTEEELFIKEEGAYETGSGGAEEEAEDLSAPSAAYTAEPRPFK 506

Query: 448 CEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIRHGSRRHGV----CTD 503
           C +C K +     +++H   H   + + C +C ++F    ++  RH     G+    C +
Sbjct: 507 CSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTM-TRHMRSHLGLKPFACDE 565

Query: 504 CAGR 507
           C  R
Sbjct: 566 CGMR 569



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 26/70 (37%), Positives = 39/70 (55%)

Query: 414 IRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKK 473
           + + F C  C      +  + RHMRSH G +P+ C+ CG +FTR+  +  H  VHS +K 
Sbjct: 529 LTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKP 588

Query: 474 YVCKVCSRVF 483
           Y C++C   F
Sbjct: 589 YECQLCGGKF 598



 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 5/101 (4%)

Query: 411 FTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSK 470
           +T   + FKC  C  +      L++H ++H   RP+PC ICGK FT+R  M RH   H  
Sbjct: 498 YTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLG 557

Query: 471 DKKYVCKVC----SRVFMSAASVGIRHGSRRHGVCTDCAGR 507
            K + C  C    +R +     + +  G + +  C  C G+
Sbjct: 558 LKPFACDECGMRFTRQYRLTEHMRVHSGEKPY-ECQLCGGK 597



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 22/54 (40%), Positives = 32/54 (59%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHS 469
           K F C  C      Q  L  HMR H+GE+PY C++CG KFT++ ++  H  +H+
Sbjct: 559 KPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHT 612


>gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens]
          Length = 584

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 69/231 (29%), Positives = 111/231 (48%), Gaps = 26/231 (11%)

Query: 13  HYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQATV 72
           H   +L  LNEQR  G+LCDV ++VEG+ F  H++VL   S+YFK L+       +Q  V
Sbjct: 16  HSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFKKLFTS-GAVVDQQNV 74

Query: 73  THLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFI------- 125
             +D V+A+   A++DF Y+A L +++ NV +++SAA  L++  +   C D +       
Sbjct: 75  YEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVSHVCADLLDRQILAA 134

Query: 126 -----KAALDISIKSDASDEL-AEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPAD 179
                   LD+  + D  + L A+  +    S+   +L  A  A  +  PW A   S  D
Sbjct: 135 DAGADAGQLDLVDQIDQRNLLRAKEYLEFFQSNPMNSLPPAAAAAAASFPWSAFGASDDD 194

Query: 180 SSGD-----SAIASCHDGGSS----YG---KEDQEPKADGPDDVSSQPLWP 218
                    +A+A+   G  +    YG     ++ P  DG +  S+  LWP
Sbjct: 195 LDATKEAVAAAVAAVAAGDCNGLDFYGPGPPAERPPTGDGDEGDSNPGLWP 245



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 6/149 (4%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K ++C  C      Q  LK HMR HTGE+PY C+ CG  F     +K H  VH+  + Y 
Sbjct: 408 KPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQ 467

Query: 476 CKVCSRVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYL 535
           C  C + F+ +  +   H   +   C     R    P   GG           PG     
Sbjct: 468 CDSCCKTFVRSDHL---HRHLKKDGCNGVPSRRGRKPRVRGGAPDPSPGATATPGAPAQP 524

Query: 536 EDPEDPRGEAEELGED---DEGLAPEDAL 561
             P+  R   E+  +D   DE +A  D L
Sbjct: 525 SSPDARRNGQEKHFKDEDEDEDVASPDGL 553



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 28/65 (43%), Positives = 39/65 (60%)

Query: 419 KCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKV 478
           KCP C         L RH+R+HTGE+PY C IC  +FTR++ +K H   H+ +K Y+C+ 
Sbjct: 383 KCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQ 442

Query: 479 CSRVF 483
           C   F
Sbjct: 443 CGAAF 447


>gi|209413766 zinc finger and BTB domain containing 43 [Homo
           sapiens]
          Length = 467

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 117/488 (23%), Positives = 200/488 (40%), Gaps = 82/488 (16%)

Query: 17  LLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQATVTHLD 76
           +L++LN+QRQ G LCDV +VV+G +F+AHK VL  SS YF    C          +   D
Sbjct: 19  ILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYF----CDQVLLKNSRRIVLPD 74

Query: 77  IVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALDI----- 131
           ++  + F+ I+   Y+  L + +  ++  ++AASFLQM  +V  C + ++    +     
Sbjct: 75  VMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEGNPTVLCQKL 134

Query: 132 -------SIKSDASDELAE-FEIGASSSS---STEALISAVMAGRSISPWLARRTS---- 176
                  S  S + + L E FE+G+   +     + L        S    L+ + +    
Sbjct: 135 NHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGENEEESTKDELSSQLTEHEY 194

Query: 177 -PADSSGDSAIASCHDGGSS--YGKEDQEPKADGPDDVSSQPLW--PGDVGYGP-LRIKE 230
            P++SS +      HD  S+    ++ +E  +D  +   ++P++  P  + +   + +K 
Sbjct: 195 LPSNSSTE------HDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPSIMAHKRWIHVKP 248

Query: 231 EQVSPSQYGGSELPSAKDGAVQNSFSEQSAGDAWQPTGRRKN-RKNKETVRHITQQVEDD 289
           E++  +  G     +  +  V  S +        QP+G  ++    ++ V     +  D+
Sbjct: 249 ERLEQACEGMDVHATYDEHQVTESINTVQTEHTVQPSGVEEDFHIGEKKVEAEFDEQADE 308

Query: 290 SRASSPVPSFLPTSGWPFSSRDSNADL--SVTEASSSDSRGERAELYAQVEEGLLGGEAS 347
           S     V  F  +S   FS   S+ +L     EA+ +    E  E+   ++E     EAS
Sbjct: 309 SNYDEQV-DFYGSSMEEFSGERSDGNLIGHRQEAALAAGYSENIEMVTGIKE-----EAS 362

Query: 348 YLGPPLTPEKDDALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAH-SL 406
           +LG   T    D L+                             G        R  H S+
Sbjct: 363 HLGFSAT----DKLYPCQC-------------------------GKSFTHKSQRDRHMSM 393

Query: 407 SLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTL 466
            L       + + C  C      +  L  HM+ HTG +PY C IC K+F  R+   RH  
Sbjct: 394 HLG-----LRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRH-- 446

Query: 467 VHSKDKKY 474
           V S  K Y
Sbjct: 447 VTSCTKSY 454



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 29/74 (39%), Positives = 40/74 (54%), Gaps = 1/74 (1%)

Query: 411 FTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSK 470
           F+   K + C  C  S  H+    RHM  H G RPY C +CGKKF  + H+  H  +H+ 
Sbjct: 366 FSATDKLYPCQ-CGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHMKIHTG 424

Query: 471 DKKYVCKVCSRVFM 484
            K Y C +C++ FM
Sbjct: 425 IKPYECNICAKRFM 438


>gi|7662100 zinc finger and BTB domain containing 43 [Homo sapiens]
          Length = 467

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 117/488 (23%), Positives = 200/488 (40%), Gaps = 82/488 (16%)

Query: 17  LLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQATVTHLD 76
           +L++LN+QRQ G LCDV +VV+G +F+AHK VL  SS YF    C          +   D
Sbjct: 19  ILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYF----CDQVLLKNSRRIVLPD 74

Query: 77  IVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALDI----- 131
           ++  + F+ I+   Y+  L + +  ++  ++AASFLQM  +V  C + ++    +     
Sbjct: 75  VMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEGNPTVLCQKL 134

Query: 132 -------SIKSDASDELAE-FEIGASSSS---STEALISAVMAGRSISPWLARRTS---- 176
                  S  S + + L E FE+G+   +     + L        S    L+ + +    
Sbjct: 135 NHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGENEEESTKDELSSQLTEHEY 194

Query: 177 -PADSSGDSAIASCHDGGSS--YGKEDQEPKADGPDDVSSQPLW--PGDVGYGP-LRIKE 230
            P++SS +      HD  S+    ++ +E  +D  +   ++P++  P  + +   + +K 
Sbjct: 195 LPSNSSTE------HDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPSIMAHKRWIHVKP 248

Query: 231 EQVSPSQYGGSELPSAKDGAVQNSFSEQSAGDAWQPTGRRKN-RKNKETVRHITQQVEDD 289
           E++  +  G     +  +  V  S +        QP+G  ++    ++ V     +  D+
Sbjct: 249 ERLEQACEGMDVHATYDEHQVTESINTVQTEHTVQPSGVEEDFHIGEKKVEAEFDEQADE 308

Query: 290 SRASSPVPSFLPTSGWPFSSRDSNADL--SVTEASSSDSRGERAELYAQVEEGLLGGEAS 347
           S     V  F  +S   FS   S+ +L     EA+ +    E  E+   ++E     EAS
Sbjct: 309 SNYDEQV-DFYGSSMEEFSGERSDGNLIGHRQEAALAAGYSENIEMVTGIKE-----EAS 362

Query: 348 YLGPPLTPEKDDALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAH-SL 406
           +LG   T    D L+                             G        R  H S+
Sbjct: 363 HLGFSAT----DKLYPCQC-------------------------GKSFTHKSQRDRHMSM 393

Query: 407 SLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTL 466
            L       + + C  C      +  L  HM+ HTG +PY C IC K+F  R+   RH  
Sbjct: 394 HLG-----LRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRH-- 446

Query: 467 VHSKDKKY 474
           V S  K Y
Sbjct: 447 VTSCTKSY 454



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 29/74 (39%), Positives = 40/74 (54%), Gaps = 1/74 (1%)

Query: 411 FTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSK 470
           F+   K + C  C  S  H+    RHM  H G RPY C +CGKKF  + H+  H  +H+ 
Sbjct: 366 FSATDKLYPCQ-CGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHMKIHTG 424

Query: 471 DKKYVCKVCSRVFM 484
            K Y C +C++ FM
Sbjct: 425 IKPYECNICAKRFM 438


>gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens]
          Length = 677

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 46/120 (38%), Positives = 74/120 (61%), Gaps = 3/120 (2%)

Query: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
           M+   H+  + ++LN QR HG LCD  +VV  + FKAH++VL   S +F+ L+  V +  
Sbjct: 1   MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALF-SVAEGD 59

Query: 68  EQATVTHLD--IVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFI 125
           +   +  LD  +VTA+ F A+ID MY++ L L   NV++V+ AAS L +  +V+AC  ++
Sbjct: 60  QTMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDVLLAASHLHLNSVVKACKHYL 119



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 19/50 (38%), Positives = 32/50 (64%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHT 465
           +K+ C  C  + +     K+H+R HTGE+PY C  CGK+F++  H+ +H+
Sbjct: 611 RKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHS 660



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 17/46 (36%), Positives = 24/46 (52%)

Query: 442 GERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAA 487
           G R Y C+IC K F      K+H  VH+ +K Y C  C + F  ++
Sbjct: 609 GARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSS 654


>gi|8923885 myoneurin [Homo sapiens]
          Length = 610

 Score = 86.3 bits (212), Expect = 7e-17
 Identities = 45/114 (39%), Positives = 66/114 (57%), Gaps = 3/114 (2%)

Query: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
           M+ + H  HLL  LN+QR+ G LCD  +V+    FKAH+NVL   S YF  +Y   + TS
Sbjct: 1   MQYSHHCEHLLERLNKQREAGFLCDCTIVIGEFQFKAHRNVLASFSEYFGAIY---RSTS 57

Query: 68  EQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQAC 121
           E         V A GF+ +++F+Y+  L L S NV E+  AA +L++ ++V  C
Sbjct: 58  ENNVFLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYLKVEEVVTKC 111



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 31/83 (37%), Positives = 47/83 (56%), Gaps = 2/83 (2%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K +KC  C+        LK H R H+GE+PY C+ CG++F +   +  H   H+ +K YV
Sbjct: 385 KPYKCDVCNLQFATSSNLKIHARKHSGEKPYVCDRCGQRFAQASTLTYHVRRHTGEKPYV 444

Query: 476 CKVCSRVFMSAASVGIRHGSRRH 498
           C  C + F  ++S+ I H SR+H
Sbjct: 445 CDTCGKAFAVSSSL-ITH-SRKH 465



 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 35/97 (36%), Positives = 55/97 (56%), Gaps = 6/97 (6%)

Query: 416 KKFKCPYCSFSAMHQCI-LKRHMRSHTGERPYPCEICGKKFTRREHMKRHT-LVHSKDKK 473
           K + C  C   A  QC  LK H+R+HTGE+PY CE+C K F ++  +  H+ + H ++K 
Sbjct: 328 KPYVCHLCG-KAFTQCNQLKTHVRTHTGEKPYKCELCDKGFAQKCQLVFHSRMHHGEEKP 386

Query: 474 YVCKVCSRVFMSAASVGI---RHGSRRHGVCTDCAGR 507
           Y C VC+  F +++++ I   +H   +  VC  C  R
Sbjct: 387 YKCDVCNLQFATSSNLKIHARKHSGEKPYVCDRCGQR 423



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 415 RKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKY 474
           + K  C  C         L+RHMR H G +PY C +CGK FT+   +K H   H+ +K Y
Sbjct: 299 KAKPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHLCGKAFTQCNQLKTHVRTHTGEKPY 358

Query: 475 VCKVCSRVFMSAASVGIRHGSRRHG 499
            C++C + F     + + H    HG
Sbjct: 359 KCELCDKGFAQKCQL-VFHSRMHHG 382



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGE-RPYPCEICGKKFTRREHMKRHTLVHSKDKKY 474
           K +KC  C      +C L  H R H GE +PY C++C  +F    ++K H   HS +K Y
Sbjct: 356 KPYKCELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVCNLQFATSSNLKIHARKHSGEKPY 415

Query: 475 VCKVCSRVFMSAASVGI---RHGSRRHGVCTDC 504
           VC  C + F  A+++     RH   +  VC  C
Sbjct: 416 VCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTC 448



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K + C  C         L  H+R HTGE+PY C+ CGK F     +  H+  H+ +K Y+
Sbjct: 413 KPYVCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGKAFAVSSSLITHSRKHTGEKPYI 472

Query: 476 CKVCSRVFMSAASVGIR---HGSRRHGVCTDC 504
           C +C + F+S+  +      H   R  +C  C
Sbjct: 473 CGICGKSFISSGELNKHFRSHTGERPFICELC 504



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 1/83 (1%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K + C  C  +      L  H R HTGE+PY C ICGK F     + +H   H+ ++ ++
Sbjct: 441 KPYVCDTCGKAFAVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRSHTGERPFI 500

Query: 476 CKVCSRVFMSAASVGIRHGSRRH 498
           C++C   +    ++  +H ++ H
Sbjct: 501 CELCGNSYTDIKNLK-KHKTKVH 522


>gi|13540490 BTB and CNC homology 1, basic leucine zipper
           transcription factor 2 [Homo sapiens]
          Length = 841

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 46/121 (38%), Positives = 71/121 (58%), Gaps = 2/121 (1%)

Query: 9   EITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSE 68
           E T H  ++L  LN+QR+  +LCDV ++VE K F+AH+ VL   S YF      V +T  
Sbjct: 15  ESTVHCTNILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYF--WQALVGQTKN 72

Query: 69  QATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAA 128
              V+  + VTA+GF  ++ F Y+A L L+  N+ EV+  A FL+M ++  +C  F++  
Sbjct: 73  DLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMHNLEDSCFSFLQTQ 132

Query: 129 L 129
           L
Sbjct: 133 L 133


>gi|45827690 BTB and CNC homology 1 transcription factor isoform a
           [Homo sapiens]
          Length = 736

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 45/118 (38%), Positives = 70/118 (59%), Gaps = 2/118 (1%)

Query: 9   EITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSE 68
           E + H  ++L  LN+QR+  VLCDV + VEG+ F+AH++VL   S YF +    V +   
Sbjct: 12  ESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRI--VGQADG 69

Query: 69  QATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIK 126
           +  +T  + VT +GF+ +I F Y+A L L+  NV EV     FL + +I ++C  F+K
Sbjct: 70  ELNITLPEEVTVKGFEPLIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLK 127


>gi|4502353 BTB and CNC homology 1 transcription factor isoform a
           [Homo sapiens]
          Length = 736

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 45/118 (38%), Positives = 70/118 (59%), Gaps = 2/118 (1%)

Query: 9   EITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSE 68
           E + H  ++L  LN+QR+  VLCDV + VEG+ F+AH++VL   S YF +    V +   
Sbjct: 12  ESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRI--VGQADG 69

Query: 69  QATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIK 126
           +  +T  + VT +GF+ +I F Y+A L L+  NV EV     FL + +I ++C  F+K
Sbjct: 70  ELNITLPEEVTVKGFEPLIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLK 127


>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
          Length = 619

 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 43/129 (33%), Positives = 74/129 (57%), Gaps = 1/129 (0%)

Query: 12  SHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQAT 71
           +H   +L  LNEQR  G+LCDV +VV+ + ++ H++VL   S+YFK L+      + Q  
Sbjct: 15  NHSSEVLCSLNEQRHDGLLCDVLLVVQEQEYRTHRSVLAACSKYFKKLF-TAGTLASQPY 73

Query: 72  VTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALDI 131
           V  +D V  +   AI++F Y++ L +T+ NV  +++AA  L++  IV  C + ++   D 
Sbjct: 74  VYEIDFVQPEALAAILEFAYTSTLTITAGNVKHILNAARMLEIQCIVNVCLEIMEPGGDG 133

Query: 132 SIKSDASDE 140
             + D  D+
Sbjct: 134 GEEDDKEDD 142



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 28/66 (42%), Positives = 41/66 (62%)

Query: 419 KCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKV 478
           +CP C    M    L RHMR+HTGE+PY C IC  +FTR++ +K H   H+ ++ Y+C  
Sbjct: 365 QCPICHKVIMGAGKLPRHMRTHTGEKPYMCTICEVRFTRQDKLKIHMRKHTGERPYLCIH 424

Query: 479 CSRVFM 484
           C+  F+
Sbjct: 425 CNAKFV 430



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K + C  C      Q  LK HMR HTGERPY C  C  KF     +K H  +H+  + Y 
Sbjct: 390 KPYMCTICEVRFTRQDKLKIHMRKHTGERPYLCIHCNAKFVHNYDLKNHMRIHTGVRPYQ 449

Query: 476 CKVCSRVF 483
           C+ C + F
Sbjct: 450 CEFCYKSF 457



 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 24/49 (48%), Positives = 31/49 (63%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRH 464
           + + C +C+   +H   LK HMR HTG RPY CE C K FTR +H+ RH
Sbjct: 418 RPYLCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRH 466


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 63/190 (33%), Positives = 85/190 (44%), Gaps = 22/190 (11%)

Query: 348 YLGPPLTPEKDDALHQATAVANLRAA----LMSKNSLLSLKADVLGDDGSLLFEYLPRGA 403
           YL PP  P  D     A A A +  A    L+  + LL   A   G  GS        GA
Sbjct: 492 YLLPPDPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGS--------GA 543

Query: 404 HSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKR 463
                   +V  K F C  C      +  LKRH R HTGE+P+ C +CGK+F    H+ +
Sbjct: 544 --------SVPGKTFCCGICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSK 595

Query: 464 HTLVHSKDKKYVCKVCSRVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGS 523
           H +VH++++ Y C++C +VF    S+  RH  + H +   CA  G AG     G  G   
Sbjct: 596 HHVVHTRERPYKCELCGKVFGYPQSL-TRH-RQVHRLQLPCALAGAAGLPSTQGTPGACG 653

Query: 524 PEALFPGDGP 533
           P A     GP
Sbjct: 654 PGASGTSAGP 663



 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 35/107 (32%), Positives = 60/107 (56%), Gaps = 4/107 (3%)

Query: 402 GAHSLSLNEFTVIRKK-FKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREH 460
           GA+ L L+  +  +K+ F+CP C        +L RH R HT +RPY C +CG+ F R  +
Sbjct: 831 GAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWY 890

Query: 461 MKRHTLVHSKDKKYVCKVCSRVFMSAASVGIR---HGSRRHGVCTDC 504
           +++H +VH+ ++ + C VC++ F  ++S+      H   R   C+ C
Sbjct: 891 LRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSAC 937



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 48/157 (30%), Positives = 62/157 (39%), Gaps = 28/157 (17%)

Query: 418 FKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKD-KKYVC 476
           F CP C         L +H   HTGE+P+ C +C K F RRE +KRH   HS D  +  C
Sbjct: 350 FACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSADLLRLPC 409

Query: 477 KVCSRVFM--------SAASVGIRHGSRRHGVCTDCAGRGMAGP---LDH---------- 515
            +C + F          AA  G   G  R     D  G+  + P   L H          
Sbjct: 410 GICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHKAAHAPPAAA 469

Query: 516 -----GGGGGEGSPEALFPGDGPYLEDPEDPRGEAEE 547
                 G      P   FP  GPYL  P+ P  ++E+
Sbjct: 470 AEAPKDGAASAPQPPPTFP-PGPYLLPPDPPTTDSEK 505



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 7/100 (7%)

Query: 413 VIRKKFKCPYC--SFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSK 470
           ++R+   C  C  SF+  +  +L  H RSH  +R + C +CGK+F     + RH   H++
Sbjct: 815 LVRRTLGCGLCGQSFAGAYDLLL--HRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTE 872

Query: 471 DKKYVCKVCSRVFMSA---ASVGIRHGSRRHGVCTDCAGR 507
            + Y C VC R F+ +       + H   R   C  CA R
Sbjct: 873 QRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKR 912



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 1/70 (1%)

Query: 443 ERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIRHGSRRHGVCT 502
           ER +PC +C K F +  H+ +H LVHS ++ Y C VC R +   +S+ IRH      V  
Sbjct: 221 ERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSL-IRHRRCHKDVPP 279

Query: 503 DCAGRGMAGP 512
              G    GP
Sbjct: 280 AAGGPPQPGP 289



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           + FKC  C+        L  H R H   RP  C  CGK F  R ++  H  +H  ++ Y 
Sbjct: 902 RAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERAYR 961

Query: 476 CKVCSRVFMSAASVGIRH 493
           C+ C + F   +SV +RH
Sbjct: 962 CEHCGKGFFYLSSV-LRH 978



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 42/161 (26%), Positives = 64/161 (39%), Gaps = 39/161 (24%)

Query: 442 GERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIRHGSRRH--- 498
           G+ P+ C +C K F +  H+ +H ++H+ +K + C VCS+ F    S  ++   + H   
Sbjct: 346 GDGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRES--LKRHVKTHSAD 403

Query: 499 ------GVCTDCAGRGMAGPLDH---GGGGGEGSPEALFPGD--GPYLEDPED------- 540
                 G+C   A R  +  L H     G G G P  ++P D  G     P+        
Sbjct: 404 LLRLPCGICGK-AFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHKAA 462

Query: 541 --PRGEAEELGEDDEGLAPEDALLADDKDEEDSPRPRSPPG 579
             P   A E  +D    AP+             P P  PPG
Sbjct: 463 HAPPAAAAEAPKDGAASAPQ-------------PPPTFPPG 490



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 18/69 (26%), Positives = 34/69 (49%)

Query: 415 RKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKY 474
           ++ ++C  C    +    L++H   HTGER + C +C K+F +   +  H  +H+  +  
Sbjct: 873 QRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQ 932

Query: 475 VCKVCSRVF 483
            C  C + F
Sbjct: 933 RCSACGKTF 941



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 19/56 (33%), Positives = 29/56 (51%)

Query: 413 VIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVH 468
           ++ ++F C  C  S      L +HM  H+GERPY C +CG+ +     + RH   H
Sbjct: 219 LMERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCH 274



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 35/117 (29%), Positives = 46/117 (39%), Gaps = 8/117 (6%)

Query: 401  RGAHSLSLNEFT---VIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTR 457
            R A S SL E      + +  +C  C  +  ++  L  H R H GER Y CE CGK F  
Sbjct: 912  RFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFY 971

Query: 458  REHMKRHTLVHSKDKKYV-CKVCSRVFMSAASVG---IRHGSRRHGVCTDCAGRGMA 510
               + RH   H   +  + C  C + F            H   R   C+ C G G A
Sbjct: 972  LSSVLRHQRAHEPPRAELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSC-GEGFA 1027



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 17/57 (29%), Positives = 29/57 (50%)

Query: 415  RKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKD 471
            R + +CP C  +       ++H+ +H G RP+ C  CG+ F     +K+H L H  +
Sbjct: 986  RAELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAE 1042



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           ++F C  C  S  H   L  H   H   R   C +CG+ F     +  H   H + + + 
Sbjct: 790 ERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQKRGFR 849

Query: 476 CKVCSRVFMSAASVGIRH 493
           C VC + F  AA + +RH
Sbjct: 850 CPVCGKRFWEAALL-MRH 866



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 15/33 (45%), Positives = 19/33 (57%)

Query: 436 HMRSHTGERPYPCEICGKKFTRREHMKRHTLVH 468
           H   H  E+PY C+ CGK F   E++  H LVH
Sbjct: 687 HKEVHMAEKPYGCDACGKTFGFIENLMWHKLVH 719



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 14/38 (36%), Positives = 18/38 (47%)

Query: 446 YPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVF 483
           Y C  CG+ F    H+  H  VH  +K Y C  C + F
Sbjct: 669 YACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTF 706


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 63/190 (33%), Positives = 85/190 (44%), Gaps = 22/190 (11%)

Query: 348 YLGPPLTPEKDDALHQATAVANLRAA----LMSKNSLLSLKADVLGDDGSLLFEYLPRGA 403
           YL PP  P  D     A A A +  A    L+  + LL   A   G  GS        GA
Sbjct: 492 YLLPPDPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGS--------GA 543

Query: 404 HSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKR 463
                   +V  K F C  C      +  LKRH R HTGE+P+ C +CGK+F    H+ +
Sbjct: 544 --------SVPGKTFCCGICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSK 595

Query: 464 HTLVHSKDKKYVCKVCSRVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGS 523
           H +VH++++ Y C++C +VF    S+  RH  + H +   CA  G AG     G  G   
Sbjct: 596 HHVVHTRERPYKCELCGKVFGYPQSL-TRH-RQVHRLQLPCALAGAAGLPSTQGTPGACG 653

Query: 524 PEALFPGDGP 533
           P A     GP
Sbjct: 654 PGASGTSAGP 663



 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 35/107 (32%), Positives = 60/107 (56%), Gaps = 4/107 (3%)

Query: 402 GAHSLSLNEFTVIRKK-FKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREH 460
           GA+ L L+  +  +K+ F+CP C        +L RH R HT +RPY C +CG+ F R  +
Sbjct: 831 GAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWY 890

Query: 461 MKRHTLVHSKDKKYVCKVCSRVFMSAASVGIR---HGSRRHGVCTDC 504
           +++H +VH+ ++ + C VC++ F  ++S+      H   R   C+ C
Sbjct: 891 LRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSAC 937



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 48/157 (30%), Positives = 62/157 (39%), Gaps = 28/157 (17%)

Query: 418 FKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKD-KKYVC 476
           F CP C         L +H   HTGE+P+ C +C K F RRE +KRH   HS D  +  C
Sbjct: 350 FACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSADLLRLPC 409

Query: 477 KVCSRVFM--------SAASVGIRHGSRRHGVCTDCAGRGMAGP---LDH---------- 515
            +C + F          AA  G   G  R     D  G+  + P   L H          
Sbjct: 410 GICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHKAAHAPPAAA 469

Query: 516 -----GGGGGEGSPEALFPGDGPYLEDPEDPRGEAEE 547
                 G      P   FP  GPYL  P+ P  ++E+
Sbjct: 470 AEAPKDGAASAPQPPPTFP-PGPYLLPPDPPTTDSEK 505



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 7/100 (7%)

Query: 413 VIRKKFKCPYC--SFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSK 470
           ++R+   C  C  SF+  +  +L  H RSH  +R + C +CGK+F     + RH   H++
Sbjct: 815 LVRRTLGCGLCGQSFAGAYDLLL--HRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTE 872

Query: 471 DKKYVCKVCSRVFMSA---ASVGIRHGSRRHGVCTDCAGR 507
            + Y C VC R F+ +       + H   R   C  CA R
Sbjct: 873 QRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKR 912



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 1/70 (1%)

Query: 443 ERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIRHGSRRHGVCT 502
           ER +PC +C K F +  H+ +H LVHS ++ Y C VC R +   +S+ IRH      V  
Sbjct: 221 ERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSL-IRHRRCHKDVPP 279

Query: 503 DCAGRGMAGP 512
              G    GP
Sbjct: 280 AAGGPPQPGP 289



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           + FKC  C+        L  H R H   RP  C  CGK F  R ++  H  +H  ++ Y 
Sbjct: 902 RAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERAYR 961

Query: 476 CKVCSRVFMSAASVGIRH 493
           C+ C + F   +SV +RH
Sbjct: 962 CEHCGKGFFYLSSV-LRH 978



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 42/161 (26%), Positives = 64/161 (39%), Gaps = 39/161 (24%)

Query: 442 GERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIRHGSRRH--- 498
           G+ P+ C +C K F +  H+ +H ++H+ +K + C VCS+ F    S  ++   + H   
Sbjct: 346 GDGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRES--LKRHVKTHSAD 403

Query: 499 ------GVCTDCAGRGMAGPLDH---GGGGGEGSPEALFPGD--GPYLEDPED------- 540
                 G+C   A R  +  L H     G G G P  ++P D  G     P+        
Sbjct: 404 LLRLPCGICGK-AFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHKAA 462

Query: 541 --PRGEAEELGEDDEGLAPEDALLADDKDEEDSPRPRSPPG 579
             P   A E  +D    AP+             P P  PPG
Sbjct: 463 HAPPAAAAEAPKDGAASAPQ-------------PPPTFPPG 490



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 18/69 (26%), Positives = 34/69 (49%)

Query: 415 RKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKY 474
           ++ ++C  C    +    L++H   HTGER + C +C K+F +   +  H  +H+  +  
Sbjct: 873 QRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQ 932

Query: 475 VCKVCSRVF 483
            C  C + F
Sbjct: 933 RCSACGKTF 941



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 19/56 (33%), Positives = 29/56 (51%)

Query: 413 VIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVH 468
           ++ ++F C  C  S      L +HM  H+GERPY C +CG+ +     + RH   H
Sbjct: 219 LMERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCH 274



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 35/117 (29%), Positives = 46/117 (39%), Gaps = 8/117 (6%)

Query: 401  RGAHSLSLNEFT---VIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTR 457
            R A S SL E      + +  +C  C  +  ++  L  H R H GER Y CE CGK F  
Sbjct: 912  RFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFY 971

Query: 458  REHMKRHTLVHSKDKKYV-CKVCSRVFMSAASVG---IRHGSRRHGVCTDCAGRGMA 510
               + RH   H   +  + C  C + F            H   R   C+ C G G A
Sbjct: 972  LSSVLRHQRAHEPPRPELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSC-GEGFA 1027



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 17/57 (29%), Positives = 29/57 (50%)

Query: 415  RKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKD 471
            R + +CP C  +       ++H+ +H G RP+ C  CG+ F     +K+H L H  +
Sbjct: 986  RPELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAE 1042



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           ++F C  C  S  H   L  H   H   R   C +CG+ F     +  H   H + + + 
Sbjct: 790 ERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQKRGFR 849

Query: 476 CKVCSRVFMSAASVGIRH 493
           C VC + F  AA + +RH
Sbjct: 850 CPVCGKRFWEAALL-MRH 866



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 15/33 (45%), Positives = 19/33 (57%)

Query: 436 HMRSHTGERPYPCEICGKKFTRREHMKRHTLVH 468
           H   H  E+PY C+ CGK F   E++  H LVH
Sbjct: 687 HKEVHMAEKPYGCDACGKTFGFIENLMWHKLVH 719



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 14/38 (36%), Positives = 18/38 (47%)

Query: 446 YPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVF 483
           Y C  CG+ F    H+  H  VH  +K Y C  C + F
Sbjct: 669 YACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTF 706


>gi|212286156 zinc finger and BTB domain containing 42 [Homo
           sapiens]
          Length = 422

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 48/114 (42%), Positives = 60/114 (52%)

Query: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
           ME   H   LL  L +QR+ G LCD  V+V    F AH+ VL   S YF   Y      S
Sbjct: 1   MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGS 60

Query: 68  EQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQAC 121
                 + DIVTA  F  ++DFMY   L L S  V +V++AAS+L M DIV+ C
Sbjct: 61  RDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVC 114



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 31/79 (39%), Positives = 46/79 (58%), Gaps = 1/79 (1%)

Query: 420 CPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVC 479
           CP C  +      LKRH R+H+GE+PY C  CGK F    ++ RHT+VH+++K + C+ C
Sbjct: 336 CPLCGKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWC 395

Query: 480 SRVFMSAASVGIRHGSRRH 498
            R F  +  +  RH  + H
Sbjct: 396 ERRFTQSGDL-YRHVRKFH 413



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 17/49 (34%), Positives = 25/49 (51%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRH 464
           K + C  C  S  +   L RH   HT E+P+ C  C ++FT+   + RH
Sbjct: 360 KPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFTQSGDLYRH 408


>gi|8922854 kelch-like 26 [Homo sapiens]
          Length = 615

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 52/145 (35%), Positives = 76/145 (52%), Gaps = 2/145 (1%)

Query: 12  SHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQAT 71
           SH   LL+ L   R  G L DV + +  + F AHK VL   S YF+ ++    + + Q  
Sbjct: 44  SHSTSLLQGLATLRAQGQLLDVVLTINREAFPAHKVVLAACSDYFRAMFTGGMREASQ-D 102

Query: 72  VTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALDI 131
           V  L  V+A+G + IIDF YSA + L    V +V+ AA FLQM  +V+ C +F+KAA+ +
Sbjct: 103 VIELKGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEEFLKAAMSV 162

Query: 132 SIKSDASDELAEFEIGASSSSSTEA 156
               +       F + AS   S +A
Sbjct: 163 ETCLNIGQMATTFSL-ASLRESVDA 186


>gi|38044286 zinc finger protein 547 [Homo sapiens]
          Length = 402

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 35/93 (37%), Positives = 54/93 (58%), Gaps = 5/93 (5%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           + +KC  C    M +  L RH R+HTGERPY C  CGK F  + H+ RH  +HS ++ Y 
Sbjct: 182 RTYKCSKCGILFMERSTLNRHQRTHTGERPYECNECGKAFLCKSHLVRHQTIHSGERPYE 241

Query: 476 CKVCSRVFMSAASV----GIRHGSRRHGVCTDC 504
           C  C ++FM ++++     +  G R +G C++C
Sbjct: 242 CSECGKLFMWSSTLITHQRVHTGKRPYG-CSEC 273



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 26/71 (36%), Positives = 40/71 (56%)

Query: 415 RKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKY 474
           ++ + C  C    M +  L RH R HTGERPY C  CGK F+ +  + +H  VH+ ++ Y
Sbjct: 293 KRSYGCSECGKFFMERSTLSRHQRVHTGERPYECNECGKFFSLKSVLIQHQRVHTGERPY 352

Query: 475 VCKVCSRVFMS 485
            C  C + F++
Sbjct: 353 ECSECGKAFLT 363



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 5/93 (5%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K F C  C  +  H+  L  H + HTGER Y C  CG  F  R  + RH   H+ ++ Y 
Sbjct: 154 KTFLCSECGKAFSHKHKLSDHQKIHTGERTYKCSKCGILFMERSTLNRHQRTHTGERPYE 213

Query: 476 CKVCSRVFMSAASVGIRHGSRRHG----VCTDC 504
           C  C + F+  + + +RH +   G     C++C
Sbjct: 214 CNECGKAFLCKSHL-VRHQTIHSGERPYECSEC 245



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 3/92 (3%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           + ++C  C    M    L  H R HTG+RPY C  CGK F    ++ RH  +H+  + Y 
Sbjct: 238 RPYECSECGKLFMWSSTLITHQRVHTGKRPYGCSECGKFFKCNSNLFRHYRIHTGKRSYG 297

Query: 476 CKVCSRVFMSAASVGIR---HGSRRHGVCTDC 504
           C  C + FM  +++      H   R   C +C
Sbjct: 298 CSECGKFFMERSTLSRHQRVHTGERPYECNEC 329



 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 33/94 (35%), Positives = 45/94 (47%), Gaps = 5/94 (5%)

Query: 415 RKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKY 474
           ++ + C  C         L RH R HTG+R Y C  CGK F  R  + RH  VH+ ++ Y
Sbjct: 265 KRPYGCSECGKFFKCNSNLFRHYRIHTGKRSYGCSECGKFFMERSTLSRHQRVHTGERPY 324

Query: 475 VCKVCSRVFMSAASVGIR----HGSRRHGVCTDC 504
            C  C + F S  SV I+    H   R   C++C
Sbjct: 325 ECNECGK-FFSLKSVLIQHQRVHTGERPYECSEC 357



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           + ++C  C  + + +  L RH   H+GERPY C  CGK F     +  H  VH+  + Y 
Sbjct: 210 RPYECNECGKAFLCKSHLVRHQTIHSGERPYECSECGKLFMWSSTLITHQRVHTGKRPYG 269

Query: 476 CKVCSRVFMSAASV----GIRHGSRRHGVCTDC 504
           C  C + F   +++     I  G R +G C++C
Sbjct: 270 CSECGKFFKCNSNLFRHYRIHTGKRSYG-CSEC 301



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 3/78 (3%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           + ++C  C      + +L +H R HTGERPY C  CGK F  + H+  H  VH+  K+  
Sbjct: 322 RPYECNECGKFFSLKSVLIQHQRVHTGERPYECSECGKAFLTKSHLICHQTVHTAAKQ-- 379

Query: 476 CKVCSRVFMSAASVGIRH 493
           C  C + F   +++ +RH
Sbjct: 380 CSECGKFFRYNSTL-LRH 396



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 433 LKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIR 492
           +K H R H   + + C  CGK F+ +  +  H  +H+ ++ Y C  C  +FM  +++   
Sbjct: 144 VKNH-RVHMAGKTFLCSECGKAFSHKHKLSDHQKIHTGERTYKCSKCGILFMERSTLNRH 202

Query: 493 ---HGSRRHGVCTDC 504
              H   R   C +C
Sbjct: 203 QRTHTGERPYECNEC 217


>gi|32469511 B-cell CLL/lymphoma 6, member B (zinc finger protein)
           [Homo sapiens]
          Length = 480

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 45/128 (35%), Positives = 74/128 (57%), Gaps = 13/128 (10%)

Query: 9   EITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSE 68
           E T H   +L  LNE R  G+L DV ++V G+  +AHK VL+  S +F +++        
Sbjct: 16  EFTRHSSDVLGNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACSGFFYSIF-------R 68

Query: 69  QATVTHLDIVT------AQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACH 122
                 +D+++      A+GF  ++DFMY++ L L+      V++AA++LQM  +VQACH
Sbjct: 69  GRAGVGVDVLSLPGGPEARGFAPLLDFMYTSRLRLSPATAPAVLAAATYLQMEHVVQACH 128

Query: 123 DFIKAALD 130
            FI+A+ +
Sbjct: 129 RFIQASYE 136



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 3/95 (3%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K +KC  C  S  ++  L  H   HTGE+PY C ICG +F R  ++K H+ +HS +K Y 
Sbjct: 327 KPYKCQLCRSSFRYKGNLASHRTVHTGEKPYHCSICGARFNRPANLKTHSRIHSGEKPYK 386

Query: 476 CKVCSRVFMSAASVG---IRHGSRRHGVCTDCAGR 507
           C+ C   F+  A +    + H   +   C  C  R
Sbjct: 387 CETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTR 421



 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 29/88 (32%), Positives = 46/88 (52%), Gaps = 1/88 (1%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K +KC  C    +    L+ H+  HTGE+PYPC  CG +F   + +K H  +H+ +K Y 
Sbjct: 383 KPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVRIHTGEKPYH 442

Query: 476 CKVCSRVFMSAASVGIRHGSRRHGVCTD 503
           C  C   F   + + + H  ++HG  T+
Sbjct: 443 CDPCGLHFRHKSQLRL-HLRQKHGAATN 469



 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 26/68 (38%), Positives = 36/68 (52%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K + C  C         LK H R H+GE+PY CE CG +F +  H++ H L+H+ +K Y 
Sbjct: 355 KPYHCSICGARFNRPANLKTHSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYP 414

Query: 476 CKVCSRVF 483
           C  C   F
Sbjct: 415 CPTCGTRF 422



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 443 ERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIR---HGSRRHG 499
           ++PY C++C   F  + ++  H  VH+ +K Y C +C   F   A++      H   +  
Sbjct: 326 DKPYKCQLCRSSFRYKGNLASHRTVHTGEKPYHCSICGARFNRPANLKTHSRIHSGEKPY 385

Query: 500 VCTDCAGR 507
            C  C  R
Sbjct: 386 KCETCGSR 393


>gi|21040324 B-cell lymphoma 6 protein isoform 1 [Homo sapiens]
          Length = 706

 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 44/122 (36%), Positives = 70/122 (57%), Gaps = 3/122 (2%)

Query: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
           ++ T H   +L  LN  R   +L DV +VV  + F+AHK VL+  S  F +++    K +
Sbjct: 9   IQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCN 68

Query: 68  EQATVTHLDI-VTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIK 126
              +V +LD  +  +GF  ++DFMY++ L L   N++ VM+ A +LQM  +V  C  FIK
Sbjct: 69  --LSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIK 126

Query: 127 AA 128
           A+
Sbjct: 127 AS 128



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 31/88 (35%), Positives = 50/88 (56%), Gaps = 1/88 (1%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K +KC  C    +    L+ H+  HTGE+PYPCEICG +F   + +K H  +H+ +K Y 
Sbjct: 600 KPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYH 659

Query: 476 CKVCSRVFMSAASVGIRHGSRRHGVCTD 503
           C+ C+  F   + + + H  ++HG  T+
Sbjct: 660 CEKCNLHFRHKSQLRL-HLRQKHGAITN 686



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 34/95 (35%), Positives = 48/95 (50%), Gaps = 3/95 (3%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K +KC  C  S  ++  L  H   HTGE+PY C ICG +F R  ++K HT +HS +K Y 
Sbjct: 544 KPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYK 603

Query: 476 CKVCSRVFMSAASVG---IRHGSRRHGVCTDCAGR 507
           C+ C   F+  A +    + H   +   C  C  R
Sbjct: 604 CETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTR 638



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 26/68 (38%), Positives = 39/68 (57%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K ++C  C         LK H R H+GE+PY CE CG +F +  H++ H L+H+ +K Y 
Sbjct: 572 KPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYP 631

Query: 476 CKVCSRVF 483
           C++C   F
Sbjct: 632 CEICGTRF 639



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 418 FKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCK 477
           F C  C      +  LKRH      ++PY C+ C   F  + ++  H  VH+ +K Y C 
Sbjct: 518 FFCNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCN 577

Query: 478 VCSRVFMSAASVGIR---HGSRRHGVCTDCAGR 507
           +C   F   A++      H   +   C  C  R
Sbjct: 578 ICGAQFNRPANLKTHTRIHSGEKPYKCETCGAR 610


>gi|197927147 B-cell lymphoma 6 protein isoform 2 [Homo sapiens]
          Length = 650

 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 44/122 (36%), Positives = 70/122 (57%), Gaps = 3/122 (2%)

Query: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
           ++ T H   +L  LN  R   +L DV +VV  + F+AHK VL+  S  F +++    K +
Sbjct: 9   IQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCN 68

Query: 68  EQATVTHLDI-VTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIK 126
              +V +LD  +  +GF  ++DFMY++ L L   N++ VM+ A +LQM  +V  C  FIK
Sbjct: 69  --LSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIK 126

Query: 127 AA 128
           A+
Sbjct: 127 AS 128



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 31/88 (35%), Positives = 50/88 (56%), Gaps = 1/88 (1%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K +KC  C    +    L+ H+  HTGE+PYPCEICG +F   + +K H  +H+ +K Y 
Sbjct: 544 KPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYH 603

Query: 476 CKVCSRVFMSAASVGIRHGSRRHGVCTD 503
           C+ C+  F   + + + H  ++HG  T+
Sbjct: 604 CEKCNLHFRHKSQLRL-HLRQKHGAITN 630



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 26/68 (38%), Positives = 39/68 (57%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K ++C  C         LK H R H+GE+PY CE CG +F +  H++ H L+H+ +K Y 
Sbjct: 516 KPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYP 575

Query: 476 CKVCSRVF 483
           C++C   F
Sbjct: 576 CEICGTRF 583



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 3/72 (4%)

Query: 439 SHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVG---IRHGS 495
           S  GE+PY C ICG +F R  ++K HT +HS +K Y C+ C   F+  A +    + H  
Sbjct: 511 SSCGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTG 570

Query: 496 RRHGVCTDCAGR 507
            +   C  C  R
Sbjct: 571 EKPYPCEICGTR 582


>gi|195927002 B-cell lymphoma 6 protein isoform 1 [Homo sapiens]
          Length = 706

 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 44/122 (36%), Positives = 70/122 (57%), Gaps = 3/122 (2%)

Query: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
           ++ T H   +L  LN  R   +L DV +VV  + F+AHK VL+  S  F +++    K +
Sbjct: 9   IQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCN 68

Query: 68  EQATVTHLDI-VTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIK 126
              +V +LD  +  +GF  ++DFMY++ L L   N++ VM+ A +LQM  +V  C  FIK
Sbjct: 69  --LSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIK 126

Query: 127 AA 128
           A+
Sbjct: 127 AS 128



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 31/88 (35%), Positives = 50/88 (56%), Gaps = 1/88 (1%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K +KC  C    +    L+ H+  HTGE+PYPCEICG +F   + +K H  +H+ +K Y 
Sbjct: 600 KPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYH 659

Query: 476 CKVCSRVFMSAASVGIRHGSRRHGVCTD 503
           C+ C+  F   + + + H  ++HG  T+
Sbjct: 660 CEKCNLHFRHKSQLRL-HLRQKHGAITN 686



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 34/95 (35%), Positives = 48/95 (50%), Gaps = 3/95 (3%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K +KC  C  S  ++  L  H   HTGE+PY C ICG +F R  ++K HT +HS +K Y 
Sbjct: 544 KPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYK 603

Query: 476 CKVCSRVFMSAASVG---IRHGSRRHGVCTDCAGR 507
           C+ C   F+  A +    + H   +   C  C  R
Sbjct: 604 CETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTR 638



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 26/68 (38%), Positives = 39/68 (57%)

Query: 416 KKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYV 475
           K ++C  C         LK H R H+GE+PY CE CG +F +  H++ H L+H+ +K Y 
Sbjct: 572 KPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYP 631

Query: 476 CKVCSRVF 483
           C++C   F
Sbjct: 632 CEICGTRF 639



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 418 FKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCK 477
           F C  C      +  LKRH      ++PY C+ C   F  + ++  H  VH+ +K Y C 
Sbjct: 518 FFCNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCN 577

Query: 478 VCSRVFMSAASVGIR---HGSRRHGVCTDCAGR 507
           +C   F   A++      H   +   C  C  R
Sbjct: 578 ICGAQFNRPANLKTHTRIHSGEKPYKCETCGAR 610


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,513,637
Number of Sequences: 37866
Number of extensions: 1352264
Number of successful extensions: 17640
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1114
Number of HSP's successfully gapped in prelim test: 136
Number of HSP's that attempted gapping in prelim test: 4945
Number of HSP's gapped (non-prelim): 10754
length of query: 589
length of database: 18,247,518
effective HSP length: 108
effective length of query: 481
effective length of database: 14,157,990
effective search space: 6809993190
effective search space used: 6809993190
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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