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Search of human proteins with 4758462
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758462 glypican 3 [Homo sapiens]
(580 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758462 glypican 3 [Homo sapiens] 1182 0.0
gi|4758464 glypican 5 [Homo sapiens] 442 e-124
gi|5031719 glypican 6 precursor [Homo sapiens] 182 7e-46
gi|21614525 glypican 4 [Homo sapiens] 169 8e-42
gi|167001141 glypican 1 precursor [Homo sapiens] 168 1e-41
gi|22749459 glypican 2 [Homo sapiens] 125 8e-29
gi|40353727 synaptopodin isoform A [Homo sapiens] 35 0.19
gi|14211935 testes development-related NYD-SP18 [Homo sapiens] 33 0.55
gi|239745081 PREDICTED: similar to Golgin subfamily A member 8-l... 33 0.72
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 32 1.2
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 32 1.2
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 32 1.2
gi|113420848 PREDICTED: hypothetical protein [Homo sapiens] 32 1.6
gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo... 32 1.6
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 32 2.1
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 32 2.1
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 32 2.1
gi|239745085 PREDICTED: similar to Golgin subfamily A member 8-l... 32 2.1
gi|239745083 PREDICTED: similar to Golgin subfamily A member 8-l... 32 2.1
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l... 31 3.6
gi|239745140 PREDICTED: similar to hect domain and RLD 2 [Homo s... 31 3.6
gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-l... 31 3.6
gi|169172800 PREDICTED: similar to Putative uncharacterized prot... 31 3.6
gi|239742767 PREDICTED: hypothetical protein XP_002342632 [Homo ... 31 3.6
gi|239741480 PREDICTED: hypothetical protein XP_002342211 [Homo ... 31 3.6
gi|239740988 PREDICTED: hypothetical protein XP_002342052 [Homo ... 31 3.6
gi|239740978 PREDICTED: hypothetical protein XP_002344292 [Homo ... 31 3.6
gi|148747556 PIN2-interacting protein 1 [Homo sapiens] 30 4.7
gi|20357504 dystonin isoform 1eB precursor [Homo sapiens] 30 4.7
gi|71061468 centromere protein E [Homo sapiens] 30 4.7
>gi|4758462 glypican 3 [Homo sapiens]
Length = 580
Score = 1182 bits (3057), Expect = 0.0
Identities = 580/580 (100%), Positives = 580/580 (100%)
Query: 1 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS 60
MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS
Sbjct: 1 MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS 60
Query: 61 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR 120
DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR
Sbjct: 61 DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR 120
Query: 121 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT 180
HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
Sbjct: 121 HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT 180
Query: 181 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI 240
QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
Sbjct: 181 QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI 240
Query: 241 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI 300
NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
Sbjct: 241 NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI 300
Query: 301 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA 360
LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA
Sbjct: 301 LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA 360
Query: 361 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT 420
YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT
Sbjct: 361 YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT 420
Query: 421 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK 480
LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK
Sbjct: 421 LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK 480
Query: 481 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ 540
GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ
Sbjct: 481 GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ 540
Query: 541 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH 580
QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
Sbjct: 541 QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH 580
>gi|4758464 glypican 5 [Homo sapiens]
Length = 572
Score = 442 bits (1137), Expect = e-124
Identities = 229/506 (45%), Positives = 328/506 (64%), Gaps = 9/506 (1%)
Query: 34 TCHQVRSFFQ-RLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQL 92
TC +VR FQ RL ++ +P++P G DLQVC+ K PTCC+RKMEE+YQ+ AR +M+Q
Sbjct: 29 TCEEVRKLFQWRLLGAVRGLPDSPRAGPDLQVCISKKPTCCTRKMEERYQIAARQDMQQF 88
Query: 93 LQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDV 152
LQ++S LKFLI +NAA FQE E +++ A+NYT+ +F + Y ++ +A V EFFTDV
Sbjct: 89 LQTSSSTLKFLISRNAAAFQETLETLIKQAENYTSILFCSTYRNMALEAAASVQEFFTDV 148
Query: 153 SLYILGSDINVDDMVNELFDSLFPVIYTQLMNPGLPDSALDINECLRGARRDLKVFGNFP 212
LY+ G+D+N ++ VN FDSLFP++Y L+NPG+ DS+L+ +EC+R ARRD+ FGN P
Sbjct: 149 GLYLFGADVNPEEFVNRFFDSLFPLVYNHLINPGVTDSSLEYSECIRMARRDVSPFGNIP 208
Query: 213 KLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVK 272
+ +M Q+ +SL +R FLQALNLGIEVINTTD+L FSK+C R L +M YC +CQGL + K
Sbjct: 209 QRVMGQMGRSLLPSRTFLQALNLGIEVINTTDYLHFSKECSRALLKMQYCPHCQGLALTK 268
Query: 273 PCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQ 332
PC GYC VM+GC+A + E++ +W YI SLEEL + M+ YD+ +VLL ++D++
Sbjct: 269 PCMGYCLNVMRGCLAHMAELNPHWHAYIRSLEELSDAMHGTYDIGHVLLNFHLLVNDAVL 328
Query: 333 YVQKNAGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKVLKVAHVEHEETLSSRRRELI 392
N KL + ++C + +S D +K +K EETL++RR+E I
Sbjct: 329 QAHLNGQKLLEQVNRICGRPVRTPTQSPRCSFDQSKEKHGMKTTTRNSEETLANRRKEFI 388
Query: 393 QKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKM 452
L+ + SFY L +C++ A + CWNG+++V+ Y+Q+ NG+K Q E+K+
Sbjct: 389 NSLRLYRSFYGGLADQLCANELAAADGLPCWNGEDIVKSYTQRVVGNGIKAQSGNPEVKV 448
Query: 453 KGPEPVVSQIIDKLKHINQLL--RTMSMPKGRVLDKNLDEEGFE--SGDCGDDEDECIGG 508
KG +PV++QIIDKLKH+ QLL R+ K +L E SGDC DDED C GG
Sbjct: 449 KGIDPVINQIIDKLKHVVQLLQGRSPKPDKWELLQLGSGGGMVEQVSGDC-DDEDGC-GG 506
Query: 509 SGDGMIKVKNQLRFLAELAYDLDVDD 534
SG G +VK L+ + D++ D
Sbjct: 507 SGSG--EVKRTLKITDWMPDDMNFSD 530
>gi|5031719 glypican 6 precursor [Homo sapiens]
Length = 555
Score = 182 bits (462), Expect = 7e-46
Identities = 131/484 (27%), Positives = 226/484 (46%), Gaps = 18/484 (3%)
Query: 34 TCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLL 93
+C +VR + L +P + G L++C P+ TCC+ +ME+K ++L E L+
Sbjct: 29 SCGEVRQAYGAKGFSLADIPYQEIAGEHLRIC-PQEYTCCTTEMEDKLSQQSKLEFENLV 87
Query: 94 QSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVS 153
+ S ++ + F E F ++ +A+ N MF Y L Q E + FT++
Sbjct: 88 EETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELK 147
Query: 154 LYILGSDINVDDMVNELFDSLFPVIYTQLMNPGLPDSALDINECLRGARRDLKVFGNFPK 213
Y G ++N+++M+N+ + L ++ QL+NP S D EC+ LK FG+ P+
Sbjct: 148 RYYTGGNVNLEEMLNDFWARLLERMF-QLINPQYHFSE-DYLECVSKYTDQLKPFGDVPR 205
Query: 214 LIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKP 273
+ QV+++ R F+Q L +G EV N + + C R L +M YC YC+GL V+P
Sbjct: 206 KLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRP 265
Query: 274 CGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQY 333
C YC VM+GC+A ++D W +I ++ + + +++E+V+ + I ++I
Sbjct: 266 CNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMN 325
Query: 334 VQKNAGKLTTTIGKLCAHSQQ----RQYRSAYYPEDL---FIDKKVLKVAHVEHEETLSS 386
+Q+N+ +++ + + C + R RSA PE+ F + +L
Sbjct: 326 MQENSMQVSAKVFQGCGQPKPAPALRSARSA--PENFNTRFRPYNPEERPTTAAGTSLDR 383
Query: 387 RRRELIQKLKSFISFYSALPGYICSHSPV---AENDTLCWNGQELVERYSQKAARNGMKN 443
++ +KLK +SALP IC V N+ CWNG RY + +G+ N
Sbjct: 384 LVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEEECWNGHSKA-RYLPEIMNDGLTN 442
Query: 444 QFNLHE--LKMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFESGDCGDD 501
Q N E + + P+ + Q I L+ + L+ DE G
Sbjct: 443 QINNPEVDVDITRPDTFIRQQIMALRVMTNKLKNAYNGNDVNFQDTSDESSGSGSGSGCM 502
Query: 502 EDEC 505
+D C
Sbjct: 503 DDVC 506
>gi|21614525 glypican 4 [Homo sapiens]
Length = 556
Score = 169 bits (427), Expect = 8e-42
Identities = 129/497 (25%), Positives = 234/497 (47%), Gaps = 42/497 (8%)
Query: 34 TCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLL 93
+C +VR + P + G L++C P+G TCCS++MEEKY L ++ + + ++
Sbjct: 29 SCSEVRRLYVSKGFNKNDAPLHEINGDHLKIC-PQGSTCCSQEMEEKYSLQSKDDFKSVV 87
Query: 94 QSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVS 153
L+ + F E F+ ++ +A+ N MF Y L Q E + F ++
Sbjct: 88 SEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELK 147
Query: 154 LYILGSDINVDDMVNE----LFDSLFPVIYTQLMNPGLPDSALDINECLRGARRDLKVFG 209
Y + ++N+++M+N+ L + +F ++ +Q D L EC+ LK FG
Sbjct: 148 RYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYH---FTDEYL---ECVSKYTEQLKPFG 201
Query: 210 NFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLM 269
+ P+ + QV+++ R F Q L + +V++ + + C L +M YCS+C+GL+
Sbjct: 202 DVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNPTAQCTHALLKMIYCSHCRGLV 261
Query: 270 MVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHD 329
VKPC YC+ +M+GC+A ++D W +I ++ + + +++E+V+ + I D
Sbjct: 262 TVKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISD 321
Query: 330 SIQYVQKNAGKLTTTIGKLCAHSQQRQYR--SAYYPEDLFIDKKVLKVAHVEHEET---- 383
+I +Q N+ +++ + + C + S E F + + H E T
Sbjct: 322 AIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSAR--FRPHHPEERPTTAAG 379
Query: 384 --LSSRRRELIQKLKSFISFYSALPGYICSHSPVAE---NDTLCWNGQELVERYSQKAAR 438
L ++ +KLK F+S+LP +C+ +A N+ CWNG+ RY
Sbjct: 380 TSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNEDDCWNGKG-KSRYLFAVTG 438
Query: 439 NGMKNQFNLHELKMKGPEP---VVSQIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFES 495
NG+ NQ N E+++ +P ++ QI+ LR M+ + N D + F+
Sbjct: 439 NGLANQGNNPEVQVDTSKPDILILRQIM--------ALRVMTSKMKNAYNGN-DVDFFDI 489
Query: 496 GDCGDDEDECIGGSGDG 512
D E GSG G
Sbjct: 490 SDESSGE-----GSGSG 501
>gi|167001141 glypican 1 precursor [Homo sapiens]
Length = 558
Score = 168 bits (426), Expect = 1e-41
Identities = 125/492 (25%), Positives = 232/492 (47%), Gaps = 29/492 (5%)
Query: 24 AQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQL 83
A+ P +C +VR + L VP+ + G L++C P+G TCC+ +MEE
Sbjct: 21 ARGDPASKSRSCGEVRQIYGAKGFSLSDVPQAEISGEHLRIC-PQGYTCCTSEMEENLAN 79
Query: 84 TARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFE 143
+ +E L+ +S L+ ++ F + F+ ++ ++ A F + L Q
Sbjct: 80 RSHAELETALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFPGAFGELYTQNAR 139
Query: 144 FVGEFFTDVSLYILGSDINVDDMVNE----LFDSLFPVIYTQLMNPGLPDSALDINECLR 199
+ ++++ LY G+++++++ + E L + LF ++ QL+ LPD LD CL
Sbjct: 140 AFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLL---LPDDYLD---CLG 193
Query: 200 GARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRM 259
L+ FG P+ + + +++ R F+Q L + +V+ + +C R + ++
Sbjct: 194 KQAEALRPFGEAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLGPECSRAVMKL 253
Query: 260 WYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENV 319
YC++C G+ +PC YC V++GC+A ++D WR + S+ + + + +E+V
Sbjct: 254 VYCAHCLGVPGARPCPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGTSGVESV 313
Query: 320 LLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKVLKVAHVE 379
+ + + + ++I +Q N LT + + C + + PE+ ++ K+A E
Sbjct: 314 IGSVHTWLAEAINALQDNRDTLTAKVIQGCGNPKVNPQGPG--PEE---KRRRGKLAPRE 368
Query: 380 H--EETLSSRRRELIQKLKSFISFYSALPGYICSHSPV--AENDTLCWNGQELVERYSQK 435
TL E +L+ F+ +LPG +CS +D CWNG RY +
Sbjct: 369 RPPSGTLEKLVSEAKAQLRDVQDFWISLPGTLCSEKMALSTASDDRCWNGMAR-GRYLPE 427
Query: 436 AARNGMKNQFNLHELK--MKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVL---DKNLDE 490
+G+ NQ N E++ + P+ + Q I +LK + LR S G + D + D
Sbjct: 428 VMGDGLANQINNPEVEVDITKPDMTIRQQIMQLKIMTNRLR--SAYNGNDVDFQDASDDG 485
Query: 491 EGFESGD-CGDD 501
G SGD C DD
Sbjct: 486 SGSGSGDGCLDD 497
>gi|22749459 glypican 2 [Homo sapiens]
Length = 579
Score = 125 bits (315), Expect = 8e-29
Identities = 121/517 (23%), Positives = 210/517 (40%), Gaps = 32/517 (6%)
Query: 10 LVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKG 69
L++ +L PG +C + R L +P + G L+VC P+
Sbjct: 7 LLLLLLPLCPGPGPGPGSEAKVTRSCAETRQVLGARGYSLNLIPPALISGEHLRVC-PQE 65
Query: 70 PTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAM 129
TCCS + E++ L++ + L + F E F ++ A++ +
Sbjct: 66 YTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQHSLTQL 125
Query: 130 FKNNYPSLTPQ-AFEFVGEFFTDVSLYIL---GSDINVDDMVNELFDSLFPVIYTQLMNP 185
F ++Y L Q A F G F Y G D + D +L + +FP+++ Q P
Sbjct: 126 FSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHPQYSFP 185
Query: 186 GLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDH 245
PD L ++ L+ FG+ P+ + Q++++L R F+Q L G V++
Sbjct: 186 --PDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSEALK 243
Query: 246 LKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEE 305
+ S+ C + L R+ C C+G+ + PC G+C V++GC++ ++ W Y+ L
Sbjct: 244 VPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSS-RGLEPDWGNYLDGLLI 302
Query: 306 LVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYYPED 365
L + + + E + I + + Y+Q+N+ K++ + + C R+ P
Sbjct: 303 LADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECGPPDPVPARNRRAPPP 362
Query: 366 LFIDKKVLKVAHVEHEETLSSRRR------ELIQKLKSFISFYSALPGYICSHSPVAEND 419
++ + E T ++ EL ++L F++ L +C S +A +
Sbjct: 363 REEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMAADA 422
Query: 420 TL----CWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRT 475
+L CW G RY Q N ELK+ P V +L QL
Sbjct: 423 SLEAAPCWTGAGR-GRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRL----QLRAA 477
Query: 476 MSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDG 512
+ K L +LD G D DE GSG G
Sbjct: 478 TARMKTAALGHDLD---------GQDADEDASGSGGG 505
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 35.0 bits (79), Expect = 0.19
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 8/57 (14%)
Query: 21 PGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPE---TPVPGSDLQVCLPKGPTCCS 74
P +A PPPPPP ++RS Q +PG VP P+P S LP GP+ C+
Sbjct: 785 PPRAPPPPPPPPPPPPRMRS-PQPARPGSAAVPGAAFAPIPRSP----LPAGPSSCT 836
>gi|14211935 testes development-related NYD-SP18 [Homo sapiens]
Length = 344
Score = 33.5 bits (75), Expect = 0.55
Identities = 31/119 (26%), Positives = 53/119 (44%), Gaps = 9/119 (7%)
Query: 377 HVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKA 436
H +H ET+ L+Q L+ +S + P + +H V +N + +LV++ Q +
Sbjct: 179 HPDHPETVFHFWIRLVQILQKGLSITTKDPRILVTHCLVPKNCSSPSGDSKLVQKKLQAS 238
Query: 437 ARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFES 495
+ +L +L KG +SQI L NQL S R ++ N + G +S
Sbjct: 239 -----QPSESLIQLMTKGESEALSQIFADLHQQNQL----SFRSSRKVETNKNSSGKDS 288
>gi|239745081 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 2 [Homo sapiens]
Length = 629
Score = 33.1 bits (74), Expect = 0.72
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 426 QELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLD 485
Q+L R + + + ++ + +L EL +K E Q + H ++ +S P GR D
Sbjct: 445 QDLESREAMSSFMDHLEEKADLSEL-VKKQELRFIQYWQERCH-QKIHHLLSEPGGRAKD 502
Query: 486 KNLDEEGFESGDCGDDEDECIGGSGDGMIKVKN 518
L ++G G DEDE G + DG+ N
Sbjct: 503 AALGGGHHQAGAQGGDEDEAAGAAADGIAAYSN 535
>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2790
Score = 32.3 bits (72), Expect = 1.2
Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 21 PGQAQP-PPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQ 63
PG P PPPPP AT FQ P P+TP+ G L+
Sbjct: 694 PGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLR 737
>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 32.3 bits (72), Expect = 1.2
Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 21 PGQAQP-PPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQ 63
PG P PPPPP AT FQ P P+TP+ G L+
Sbjct: 610 PGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLR 653
>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 32.3 bits (72), Expect = 1.2
Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 21 PGQAQP-PPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQ 63
PG P PPPPP AT FQ P P+TP+ G L+
Sbjct: 610 PGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLR 653
>gi|113420848 PREDICTED: hypothetical protein [Homo sapiens]
Length = 109
Score = 32.0 bits (71), Expect = 1.6
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 485 DKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQQATP 544
DK +DEEG ESG+ ++E E G DG + + A + D DD +Q T
Sbjct: 49 DKEVDEEGEESGEEEEEEKEGDGEEEDG--DEEEAESATGKRAAEDDEDDDVDTKKQKTD 106
Query: 545 KDN 547
KD+
Sbjct: 107 KDD 109
>gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo
sapiens]
Length = 1791
Score = 32.0 bits (71), Expect = 1.6
Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 1/29 (3%)
Query: 45 LQPGLKWVPETPVPGSDLQVCLPKGPTCC 73
LQ G W+PE VP + CLPKG CC
Sbjct: 999 LQDGFGWLPEM-VPKKQPERCLPKGFGCC 1026
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 31.6 bits (70), Expect = 2.1
Identities = 31/143 (21%), Positives = 54/143 (37%), Gaps = 10/143 (6%)
Query: 195 NECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINT--TDHLKFSKDC 252
N C + + GN P+L++T ++ +T L +G T + +KD
Sbjct: 1810 NICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDL 1869
Query: 253 GRMLTRMWYCSYCQGLMMVKPCG----GYCNVVMQGCMAGV----VEIDKYWREYILSLE 304
GR L M Y C M K CG G GC VE+ + ++
Sbjct: 1870 GRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQ 1929
Query: 305 ELVNGMYRIYDMENVLLGLFSTI 327
+ + + ++ ++GL T+
Sbjct: 1930 DAIRAKKKAFNFLGEIIGLIPTV 1952
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 31.6 bits (70), Expect = 2.1
Identities = 31/143 (21%), Positives = 54/143 (37%), Gaps = 10/143 (6%)
Query: 195 NECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINT--TDHLKFSKDC 252
N C + + GN P+L++T ++ +T L +G T + +KD
Sbjct: 1787 NICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDL 1846
Query: 253 GRMLTRMWYCSYCQGLMMVKPCG----GYCNVVMQGCMAGV----VEIDKYWREYILSLE 304
GR L M Y C M K CG G GC VE+ + ++
Sbjct: 1847 GRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQ 1906
Query: 305 ELVNGMYRIYDMENVLLGLFSTI 327
+ + + ++ ++GL T+
Sbjct: 1907 DAIRAKKKAFNFLGEIIGLIPTV 1929
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 31.6 bits (70), Expect = 2.1
Identities = 31/143 (21%), Positives = 54/143 (37%), Gaps = 10/143 (6%)
Query: 195 NECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVINT--TDHLKFSKDC 252
N C + + GN P+L++T ++ +T L +G T + +KD
Sbjct: 1787 NICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDL 1846
Query: 253 GRMLTRMWYCSYCQGLMMVKPCG----GYCNVVMQGCMAGV----VEIDKYWREYILSLE 304
GR L M Y C M K CG G GC VE+ + ++
Sbjct: 1847 GRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQ 1906
Query: 305 ELVNGMYRIYDMENVLLGLFSTI 327
+ + + ++ ++GL T+
Sbjct: 1907 DAIRAKKKAFNFLGEIIGLIPTV 1929
>gi|239745085 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 3 [Homo sapiens]
Length = 601
Score = 31.6 bits (70), Expect = 2.1
Identities = 16/43 (37%), Positives = 21/43 (48%)
Query: 476 MSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKN 518
+S P GR D L ++G G DEDE G + DG+ N
Sbjct: 465 LSEPGGRAKDAALGGGHHQAGAQGGDEDEAAGAAADGIAAYSN 507
>gi|239745083 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 4 [Homo sapiens]
Length = 590
Score = 31.6 bits (70), Expect = 2.1
Identities = 16/43 (37%), Positives = 21/43 (48%)
Query: 476 MSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKN 518
+S P GR D L ++G G DEDE G + DG+ N
Sbjct: 454 LSEPGGRAKDAALGGGHHQAGAQGGDEDEAAGAAADGIAAYSN 496
>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 30.8 bits (68), Expect = 3.6
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Query: 426 QELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLD 485
++L R + + + +K + +L EL +K E Q + H ++ +S P GR D
Sbjct: 448 EDLESREAMSSFMDHLKEKADLSEL-VKKQELRFIQYWQERCH-QKIHHLLSEPGGRAKD 505
Query: 486 KNLDEEGFESGDCGDDEDECIGGSGDGMIKVKN 518
L ++G G DE E G + DG+ N
Sbjct: 506 AALGGGHHQAGAQGGDEGEAAGAAADGIAAYSN 538
>gi|239745140 PREDICTED: similar to hect domain and RLD 2 [Homo
sapiens]
Length = 1052
Score = 30.8 bits (68), Expect = 3.6
Identities = 36/157 (22%), Positives = 65/157 (41%), Gaps = 14/157 (8%)
Query: 368 IDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPG------YICSHSPVAENDTL 421
+ +K+ +V EH E S + ++L +L ALPG ++ S A +
Sbjct: 432 LQEKLGEVKDTEHLEAASQQNQQLTAQLSLM-----ALPGEGHGGEHLDSDGEEAPRP-M 485
Query: 422 CWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPKG 481
++L R + + + ++ + +L EL K + D+ ++ +S P G
Sbjct: 486 PSVPEDLESREAMSSFMDQLEEKADLSELVKKKELCFIHHWRDRCHQ--KIHHLLSEPGG 543
Query: 482 RVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKN 518
R D L ++G G DE E G + DG+ N
Sbjct: 544 RAKDAALVGGHHQAGAQGGDEGEAAGAAADGVAAYSN 580
>gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 4 [Homo sapiens]
Length = 632
Score = 30.8 bits (68), Expect = 3.6
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Query: 426 QELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLD 485
++L R + + + +K + +L EL +K E Q + H ++ +S P GR D
Sbjct: 448 EDLESREAMSSFMDHLKEKADLSEL-VKKQELRFIQYWQERCH-QKIHHLLSEPGGRAKD 505
Query: 486 KNLDEEGFESGDCGDDEDECIGGSGDGMIKVKN 518
L ++G G DE E G + DG+ N
Sbjct: 506 AALGGGHHQAGAQGGDEGEAAGAAADGIAAYSN 538
>gi|169172800 PREDICTED: similar to Putative uncharacterized protein
C20orf69 [Homo sapiens]
Length = 85
Score = 30.8 bits (68), Expect = 3.6
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 427 ELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKH 468
E+++ Y KAA ++ Q + K K P+P ++ K+KH
Sbjct: 20 EIIDFYKMKAASEALQTQLSTDTKKDKHPDPYEFLLLRKIKH 61
>gi|239742767 PREDICTED: hypothetical protein XP_002342632 [Homo
sapiens]
Length = 85
Score = 30.8 bits (68), Expect = 3.6
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 427 ELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKH 468
E+++ Y KAA ++ Q + K K P+P ++ K+KH
Sbjct: 20 EIIDFYKMKAASEALQTQLSTDTKKDKHPDPYEFLLLRKIKH 61
>gi|239741480 PREDICTED: hypothetical protein XP_002342211 [Homo
sapiens]
Length = 85
Score = 30.8 bits (68), Expect = 3.6
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 427 ELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKH 468
E+++ Y KAA ++ Q + K K P+P ++ K+KH
Sbjct: 20 EIIDFYKMKAASEALQTQLSTDTKKDKHPDPYEFLLLRKIKH 61
>gi|239740988 PREDICTED: hypothetical protein XP_002342052 [Homo
sapiens]
Length = 85
Score = 30.8 bits (68), Expect = 3.6
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 427 ELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKH 468
E+++ Y KAA ++ Q + K K P+P ++ K+KH
Sbjct: 20 EIIDFYKMKAASEALQTQLSTDTKKDKHPDPYEFLLLRKIKH 61
>gi|239740978 PREDICTED: hypothetical protein XP_002344292 [Homo
sapiens]
Length = 85
Score = 30.8 bits (68), Expect = 3.6
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 427 ELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKH 468
E+++ Y KAA ++ Q + K K P+P ++ K+KH
Sbjct: 20 EIIDFYKMKAASEALQTQLSTDTKKDKHPDPYEFLLLRKIKH 61
>gi|148747556 PIN2-interacting protein 1 [Homo sapiens]
Length = 328
Score = 30.4 bits (67), Expect = 4.7
Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
Query: 22 GQAQPPPPPPDAT----CHQVRSFFQRLQPGLKWVPETPVPGSDL 62
G A P P + T ++ +F + LK P+ PVPGSD+
Sbjct: 158 GDASPSTPEENETTTTSAFTIQEYFAKRMAALKNKPQVPVPGSDI 202
>gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]
Length = 3062
Score = 30.4 bits (67), Expect = 4.7
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 493 FESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQQATPKDNEISTF 552
++S D DD+D+ I G G I+ +N +A D+D+ + + ++ I+T
Sbjct: 2262 YDSNDQDDDDDDGIDEEGGG-IRDENGKPRCQNVAEDMDIQLCASILNENSDENENINTM 2320
Query: 553 HNLGNVHSPLKLLTSMAISVV 573
L +HS L ++VV
Sbjct: 2321 ILLDKMHSCSSLEKQQRVNVV 2341
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 30.4 bits (67), Expect = 4.7
Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 7/81 (8%)
Query: 370 KKVLKVAHV---EHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQ 426
K+ LK+AH+ EH+ET+ RR + +K I+ SH+ + E + Q
Sbjct: 1234 KEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEK----SHTKLQEEIPVLHEEQ 1289
Query: 427 ELVERYSQKAARNGMKNQFNL 447
EL+ + + N+ L
Sbjct: 1290 ELLPNVKEVSETQETMNELEL 1310
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,976,534
Number of Sequences: 37866
Number of extensions: 1102128
Number of successful extensions: 6143
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 6041
Number of HSP's gapped (non-prelim): 93
length of query: 580
length of database: 18,247,518
effective HSP length: 108
effective length of query: 472
effective length of database: 14,157,990
effective search space: 6682571280
effective search space used: 6682571280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.