BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4757836 BRCA1 associated protein-1 [Homo sapiens] (729 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4757836 BRCA1 associated protein-1 [Homo sapiens] 1456 0.0 gi|7706753 ubiquitin carboxyl-terminal hydrolase L5 [Homo sapiens] 185 1e-46 gi|5174741 ubiquitin carboxyl-terminal esterase L3 [Homo sapiens] 69 2e-11 gi|21361091 ubiquitin carboxyl-terminal esterase L1 [Homo sapiens] 59 1e-08 gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 44 7e-04 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 41 0.003 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 41 0.003 gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo s... 41 0.005 gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 40 0.008 gi|21328446 hormone-sensitive lipase [Homo sapiens] 39 0.013 gi|42518068 trans-golgi network protein 2 [Homo sapiens] 39 0.013 gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo s... 39 0.017 gi|91208420 bassoon protein [Homo sapiens] 39 0.017 gi|148612857 sickle tail isoform 3 [Homo sapiens] 39 0.017 gi|148612813 sickle tail isoform 2 [Homo sapiens] 39 0.017 gi|116089335 BR serine/threonine kinase 2 [Homo sapiens] 39 0.022 gi|39995080 hypothetical protein LOC79567 [Homo sapiens] 38 0.029 gi|38176300 nestin [Homo sapiens] 37 0.050 gi|24431933 reticulon 4 isoform B [Homo sapiens] 37 0.065 gi|47519490 reticulon 4 isoform D [Homo sapiens] 37 0.065 gi|24431935 reticulon 4 isoform A [Homo sapiens] 37 0.065 gi|119395716 forkhead box C1 [Homo sapiens] 37 0.065 gi|187960059 syndecan 3 [Homo sapiens] 37 0.065 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 37 0.085 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 37 0.085 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 37 0.085 gi|55741677 SET domain containing 1A [Homo sapiens] 37 0.085 gi|109637791 transcription factor-like nuclear regulator [Homo s... 37 0.085 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 36 0.11 gi|119943102 CREB binding protein isoform b [Homo sapiens] 36 0.11 >gi|4757836 BRCA1 associated protein-1 [Homo sapiens] Length = 729 Score = 1456 bits (3768), Expect = 0.0 Identities = 729/729 (100%), Positives = 729/729 (100%) Query: 1 MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRR 60 MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRR Sbjct: 1 MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRR 60 Query: 61 KVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTK 120 KVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTK Sbjct: 61 KVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTK 120 Query: 121 GFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL 180 GFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL Sbjct: 121 GFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL 180 Query: 181 FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIK 240 FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIK Sbjct: 181 FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIK 240 Query: 241 YEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANR 300 YEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANR Sbjct: 241 YEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANR 300 Query: 301 APAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF 360 APAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF Sbjct: 301 APAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF 360 Query: 361 LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKG 420 LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKG Sbjct: 361 LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKG 420 Query: 421 KGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPT 480 KGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPT Sbjct: 421 KGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPT 480 Query: 481 HSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR 540 HSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR Sbjct: 481 HSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR 540 Query: 541 VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVE 600 VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVE Sbjct: 541 VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVE 600 Query: 601 KEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKF 660 KEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKF Sbjct: 601 KEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKF 660 Query: 661 KIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKR 720 KIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKR Sbjct: 661 KIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKR 720 Query: 721 SRPYKAKRQ 729 SRPYKAKRQ Sbjct: 721 SRPYKAKRQ 729 >gi|7706753 ubiquitin carboxyl-terminal hydrolase L5 [Homo sapiens] Length = 329 Score = 185 bits (469), Expect = 1e-46 Identities = 108/250 (43%), Positives = 151/250 (60%), Gaps = 23/250 (9%) Query: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKC---QGPVYGFIFLFKWIEERRSRRK 61 W +ESDPG+FT L++ FG +G QVEEI+ L+ + PV+G IFLFKW Sbjct: 8 WCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAG- 66 Query: 62 VSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVD--LGPTLSRMKDFT 119 SV+ D ++ +FFA Q+I N+CAT A++SVLLNC+ D LG TLS K+F+ Sbjct: 67 --------SVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFS 118 Query: 120 KGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGR 179 + F KG A+ N+ + + HNS AR + K ++ + +AFHFVSYVP+ GR Sbjct: 119 QSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTK----TSAKEEDAFHFVSYVPVNGR 174 Query: 180 LFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRI 239 L+ELDGL+ PID G +D +W R VI +RI + GE IRFNLMA+V DR++ Sbjct: 175 LYELDGLREGPIDLGACNQD-DWISAVRPVIEKRIQKYSEGE----IRFNLMAIVSDRKM 229 Query: 240 KYEARLHVLK 249 YE ++ L+ Sbjct: 230 IYEQKIAELQ 239 Score = 51.2 bits (121), Expect = 3e-06 Identities = 23/61 (37%), Positives = 40/61 (65%) Query: 634 ALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVE 693 ++L +++E+A + ++EEV+K K++KI++ RR HNY FI + LA+ L LVE Sbjct: 255 SMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVE 314 Query: 694 Q 694 + Sbjct: 315 K 315 >gi|5174741 ubiquitin carboxyl-terminal esterase L3 [Homo sapiens] Length = 230 Score = 68.6 bits (166), Expect = 2e-11 Identities = 59/239 (24%), Positives = 104/239 (43%), Gaps = 27/239 (11%) Query: 5 WLELESDPGLFTLLVEDFGVK-GVQVEEIY----DLQSKCQGPVYGFIFLFKWIEERRSR 59 WL LE++P + ++ G+ Q ++Y +L S PV + LF E+ Sbjct: 6 WLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVF 65 Query: 60 RKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSS---VDLGPTLSRMK 116 R + D+ ++++F Q I N+C T L+ + N + G TL + Sbjct: 66 RTEEE--EKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFL 123 Query: 117 DFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPI 176 + + SPE + + N + H + A E Q ++ HF++ V + Sbjct: 124 EESVSMSPEERARYLENYDAIRVTHETSAH-------EGQTEAPSIDEKVDLHFIALVHV 176 Query: 177 TGRLFELDGLKVYPIDHGPWGEDEEWTD--KARRVIMERIGLATAGEPYHDIRFNLMAV 233 G L+ELDG K +PI+HG ++ D + + MER +P ++RFN +A+ Sbjct: 177 DGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMER-------DP-DELRFNAIAL 227 >gi|21361091 ubiquitin carboxyl-terminal esterase L1 [Homo sapiens] Length = 223 Score = 59.3 bits (142), Expect = 1e-08 Identities = 48/208 (23%), Positives = 86/208 (41%), Gaps = 22/208 (10%) Query: 8 LESDPGLFTLLVEDFGVKGV-QVEEIYDLQSKCQG----PVYGFIFLFKWIEERRSRRKV 62 +E +P + ++ GV G + ++ L+ + G P + LF + + RK Sbjct: 6 MEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKK 65 Query: 63 STLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSS---VDLGPTLSRMKDFT 119 + ++ ++F Q I NSC T L+ + N + G L + T Sbjct: 66 QI----EELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSET 121 Query: 120 KGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGR 179 + SPE + + AH++ A+ + +K N FHF+ + + G Sbjct: 122 EKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVN----------FHFILFNNVDGH 171 Query: 180 LFELDGLKVYPIDHGPWGEDEEWTDKAR 207 L+ELDG +P++HG ED D A+ Sbjct: 172 LYELDGRMPFPVNHGASSEDTLLKDAAK 199 >gi|58530876 melanoma antigen family C, 1 [Homo sapiens] Length = 1142 Score = 43.5 bits (101), Expect = 7e-04 Identities = 64/308 (20%), Positives = 123/308 (39%), Gaps = 42/308 (13%) Query: 278 ESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVK 337 +S L E +S +SP+ + ++ P++ + + ++ Q+P HSP + P+ Sbjct: 613 QSPLQGEEFQSSLQSPVSICSSSTPSSLPQSFPESSQSPPEGPVQSPLHSPQSPPE---- 668 Query: 338 PPGSSLNGVHP-NPTPIVQRLPAFLDNHN---YAKSPMQEEEDLAAGVGRSRVPVRPPQ- 392 G+H +P + P D+ + +SP++ E+ L++ P PP+ Sbjct: 669 -------GMHSQSPLQSPESAPEGEDSLSPLQIPQSPLEGEDSLSS----LHFPQSPPEW 717 Query: 393 ----------QYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQP 442 Q+ +D++ + V +S+ + S S LQ Sbjct: 718 EDSLSPLHFPQFPPQGEDFQSSLQSPVSICSSSTSLSLPQSFPESPQSPPEGPAQSPLQR 777 Query: 443 NTIN----VLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTH-----SQPSPTPSNEST 493 + LA L+ S + P S SP + P+ SQ SP S S+ Sbjct: 778 PVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQSSPVSSFPSS 837 Query: 494 DTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVL---FGEDDSLLRVDCIRYNRAV 550 ++S S+ SPL+SP+ S + + SP + S + D+LL D + + ++ Sbjct: 838 TSSSLSKSSPESPLQSPVISFSSSTSLSPFSEESSSPVDEYTSSSDTLLESDSLTDSESL 897 Query: 551 RDLGPVIS 558 + P+ + Sbjct: 898 IESEPLFT 905 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 41.2 bits (95), Expect = 0.003 Identities = 54/271 (19%), Positives = 107/271 (39%), Gaps = 21/271 (7%) Query: 248 LKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEG 307 +KV + ++ +++ + T +I +++E+Q+ EE K E + E Sbjct: 436 IKVKSEEKIKVVEKSEKET---VIVEEQTEETQVTEEVTEEEEKEAKE-EEGKEEEGGEE 491 Query: 308 NHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYA 367 +G EE S + SP + K VK S +P + PA + + A Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS-PAEAKSPEKEEAKSPAEVKSPEKA 550 Query: 368 KSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPG 427 KSP +EE PP+ S ++++ + E V++ A + K K Sbjct: 551 KSPAKEEAK------------SPPEAKSPEKEEAKSPAE--VKSPEKA-KSPAKEEAKSP 595 Query: 428 ALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPT 487 A + S + S ++ + AE +++ P +K+ A SP + + + Sbjct: 596 AEAKSPEKAKSPVKEEAKSP-AEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654 Query: 488 PSNESTDTASEIGSAFNSPLRSPIRSANPTR 518 P E + + S + +SP ++ +P + Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVK 685 Score = 32.0 bits (71), Expect = 2.1 Identities = 80/405 (19%), Positives = 140/405 (34%), Gaps = 54/405 (13%) Query: 269 ELIQTHKSQESQLPEESKS-ASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHS 327 E K +S + EE+KS A KSP E A + +E + A+ A A++P + Sbjct: 508 EAASPEKEAKSPVKEEAKSPAEAKSP---EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564 Query: 328 PPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVP 387 + + P +P + PA + AKSP++EE A ++ P Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEE---AKSPAEAKSP 621 Query: 388 VRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINV 447 V+ E+ E + S + + K K + Sbjct: 622 VK--------EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE----------------- 656 Query: 448 LAEKLKESQKDLS-IPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSP 506 E+ K +K S + K+ A SP A + + +P E + + S Sbjct: 657 -KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 715 Query: 507 LRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAE 566 +SP ++ +P + + + E S + + + P T A+ Sbjct: 716 AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP----AK 771 Query: 567 DGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPV-------------EKEVVEATDSREKT 613 + SP A K SP ++ + + SP+ ++EV EK Sbjct: 772 EEARSP-ADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP 830 Query: 614 GMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRK 658 V+ EP +K ++ A K E + + E K+E K K Sbjct: 831 QEVKVKEP--PKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPK 873 Score = 31.6 bits (70), Expect = 2.7 Identities = 48/256 (18%), Positives = 97/256 (37%), Gaps = 16/256 (6%) Query: 265 VTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEG----NHTDGAEEAAGSC 320 V PE ++ +E++ P E+KS V E ++PA ++ AE + Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637 Query: 321 AQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAG 380 A++P+ P+ P +P+ A + AKSP++ E A Sbjct: 638 AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPV----KAEAKSPEKAKSPVKAE---AKS 690 Query: 381 VGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGA----LSGSADGQ 436 +++ PV+ + + +E + S ++ + K K + + S + Sbjct: 691 PEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKA 750 Query: 437 LSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTA 496 S + T++V + + K K+ + + K A SP + + +P E A Sbjct: 751 KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDA-KA 809 Query: 497 SEIGSAFNSPLRSPIR 512 E ++SP++ Sbjct: 810 PEKEIPKKEEVKSPVK 825 Score = 31.6 bits (70), Expect = 2.7 Identities = 31/132 (23%), Positives = 53/132 (40%), Gaps = 16/132 (12%) Query: 252 RQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTD 311 + V E + V PE ++ +E++ PE++KS + E ++P +E + Sbjct: 619 KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE 678 Query: 312 GAEEAAGSCAQAP--SHSP-------PNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLD 362 A+ + A++P + SP P K K VK S P + Sbjct: 679 KAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS-------PEKAKSPVKEEAK 731 Query: 363 NHNYAKSPMQEE 374 AKSP++EE Sbjct: 732 TPEKAKSPVKEE 743 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 41.2 bits (95), Expect = 0.003 Identities = 57/290 (19%), Positives = 105/290 (36%), Gaps = 26/290 (8%) Query: 240 KYEARLHVLKVNRQTVLEALQQLIRVTQPE--LIQTHKSQESQLPEESKSASNKSPLVLE 297 +++A+ ++ Q V++ QQL + Q + LI+ H + Q+ ++ + + L L+ Sbjct: 188 QFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQ 247 Query: 298 ANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRL 357 + + A +A Q P PP + P P P Q L Sbjct: 248 QQQQQQQQQQQQQQQALQA-----QPPIQQPPMQ---------------QPQPPPS-QAL 286 Query: 358 PAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALR 417 P L ++ + + V +++ PPQ + + T L+ Sbjct: 287 PQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLK 346 Query: 418 YKGKG--TGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPA 475 + +P Q +V ++A ++ SQ L + S +P Sbjct: 347 FVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQ 406 Query: 476 VAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTS 525 ++P QPSP P S+ S + S S + S +P SPVT+ Sbjct: 407 -SMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTA 455 >gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo sapiens] Length = 652 Score = 40.8 bits (94), Expect = 0.005 Identities = 63/289 (21%), Positives = 106/289 (36%), Gaps = 46/289 (15%) Query: 235 PDRRIKYEARLHVLKVNRQTVLEALQ----QLIRVTQPELIQTHKSQESQLPEESKSASN 290 P+ + Y R K ++E LQ Q+ T+ + + S ++SK + Sbjct: 252 PEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSKDSDF 311 Query: 291 KSPLVLEANRAPAASE--GNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLN---- 344 L ++AP E D + EAA S + AP+ N V++ P + Sbjct: 312 WKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEE 371 Query: 345 ---GVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDY 401 G I Q P + A+ P +E E R R + +DED+ Sbjct: 372 LKGGTKKGKPNIGQEQPV----DDAAEVPQREPEKERGDPERQR-----EMEEEEDEDED 422 Query: 402 EDDEEDDVQ---------------NTNSALRYKGKGTGKPGALSGSADGQLSVLQ-PNTI 445 ED++ED+ Q + LR + + P L ++ ++L +T+ Sbjct: 423 EDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTL 482 Query: 446 NVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTD 494 N L ++L+E Q + K VP PSP P+ E + Sbjct: 483 NKLIKRLEEKQSPELVKKHKKKR--------VVPKKPPPSPQPTEEDPE 523 >gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] Length = 788 Score = 40.0 bits (92), Expect = 0.008 Identities = 56/308 (18%), Positives = 105/308 (34%), Gaps = 22/308 (7%) Query: 240 KYEARLHVLKVNRQTVLEALQQLIRVTQPE--LIQTHKSQESQLPEESKSASNKSPLVLE 297 +++A+ ++ Q V++ QQL + Q + LI+ H + Q+ ++ + + L L+ Sbjct: 188 QFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQ 247 Query: 298 ANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVH-------PNP 350 + + A +A Q P P P + ++ P Sbjct: 248 QQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQ 307 Query: 351 TPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVP---VRPPQQYSDDEDDYEDDEED 407 P+ Q P+ L + + + + + L + ++ P VR P + ++ Sbjct: 308 PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367 Query: 408 DVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINV---------LAEKLKESQKD 458 T A + G + P T V L + Sbjct: 368 TAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQ 427 Query: 459 LSIPLSIKTSSGAG-SPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPT 517 S+P+ S G ++P QPSP P S+ S + S S + S +P Sbjct: 428 SSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ 487 Query: 518 RPSSPVTS 525 SPVT+ Sbjct: 488 PSQSPVTA 495 >gi|21328446 hormone-sensitive lipase [Homo sapiens] Length = 1076 Score = 39.3 bits (90), Expect = 0.013 Identities = 61/243 (25%), Positives = 86/243 (35%), Gaps = 38/243 (15%) Query: 254 TVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGA 313 T LE + + QPE S Q P ASN+ PL + A +E A Sbjct: 23 TPLEPGPEKTPIAQPESKTLQGSNTQQKP-----ASNQRPLTQQETPAQHDAESQKEPRA 77 Query: 314 EEAAGSCAQ-------APSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNY 366 ++ + S + AP SP + L+ + +S G I Q+ PA H Sbjct: 78 QQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVA 137 Query: 367 AKSP--------MQEEEDLAAG---VGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSA 415 P QE E A G R P P + S + + D + VQ S Sbjct: 138 QPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQTTPVQGAKS- 196 Query: 416 LRYKGKGTGKPGALSGSADGQLSVLQPNTINVLA---EKLKESQKDLSIPLSIKTSSGAG 472 K G+L+ G L+ LQ +I A + L E D + +SS Sbjct: 197 ---------KQGSLTEL--GFLTKLQELSIQRSALEWKALSEWVTDSESESDVGSSSDTD 245 Query: 473 SPA 475 SPA Sbjct: 246 SPA 248 >gi|42518068 trans-golgi network protein 2 [Homo sapiens] Length = 437 Score = 39.3 bits (90), Expect = 0.013 Identities = 61/273 (22%), Positives = 98/273 (35%), Gaps = 30/273 (10%) Query: 268 PELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQ----- 322 P+ + S E+Q PE++ + S + + + +E G+ +GS AQ Sbjct: 63 PKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDS 122 Query: 323 -APSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGV 381 + SH PK G+ +P D+ + + S Q +D+ Sbjct: 123 TSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVP--- 179 Query: 382 GRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGK-GTGKPGA---------LSG 431 +S + P+ S + ED DV N + A + K G+ K GA Sbjct: 180 NKSGADGQTPKDGS-SKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKS 238 Query: 432 SADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPS--PTPS 489 A+ Q S PN + K+ K +S P K A + +A P T S Sbjct: 239 GAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTES 298 Query: 490 NESTDTASEIGSAFNSPLRSPIRSANPTRPSSP 522 E TD SP + ++S+ PT P Sbjct: 299 GEETDLI--------SPPQEEVKSSEPTEDVEP 323 Score = 32.3 bits (72), Expect = 1.6 Identities = 58/249 (23%), Positives = 90/249 (36%), Gaps = 50/249 (20%) Query: 266 TQPELIQTHKSQ------ESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGS 319 + PEL QT K E+Q PE+S + S + + + + SE T +G+ Sbjct: 126 SHPEL-QTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGA 184 Query: 320 CAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAA 379 Q P GSS +G + P + N + A+ ++ + Sbjct: 185 DGQTPK-------------DGSSKSGAE-------DQTPKDVPNKSGAEKQTPKDGSNKS 224 Query: 380 GVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSV 439 G + P+ P + +E +D V S K KP +S +D + Sbjct: 225 G-AEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSR-----KDHSKP--ISNPSDNK--E 274 Query: 440 LQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSN-------ES 492 L N LA+K K S P + KT SG + ++ P S P+ E Sbjct: 275 LPKADTNQLADKGKLS------PHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAED 328 Query: 493 TDTASEIGS 501 DT E GS Sbjct: 329 DDTGPEEGS 337 Score = 32.0 bits (71), Expect = 2.1 Identities = 79/349 (22%), Positives = 117/349 (33%), Gaps = 61/349 (17%) Query: 300 RAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPA 359 R A + H ++ GS SH P PK P SS P TP Sbjct: 34 RPSAGNVSTHPSLSQRPGGS---TKSHPEPQTPK--DSPSKSSAEAQTPEDTP------- 81 Query: 360 FLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYK 419 N + A++ Q++ +S + + + +D ++ L+ Sbjct: 82 ---NKSGAEAKTQKDSS-----NKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTP 133 Query: 420 GKGTGKPGALS---------GSADGQLSVLQPNTINVLAEKLKE----SQKDLSIPLSIK 466 TGK GA + A+ + P+ A+ K+ S D P Sbjct: 134 KDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGS 193 Query: 467 TSSGAGSPAVA-VPTHS-QPSPTPSNESTDTASEIGSAFNSPLRSPIR------SANPTR 518 + SGA VP S TP + S + +E + P +S S N Sbjct: 194 SKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVV 253 Query: 519 PSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLAL-TE 577 P P SK + D+ ++L P T LA+ G LSP A TE Sbjct: 254 PEQPSRKDHSKPISNPSDN-------------KEL-PKADTN--QLADKGKLSPHAFKTE 297 Query: 578 GGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEK 626 G+ + I P Q SS P E VE ++ + G P EK Sbjct: 298 SGE-ETDLISPPQEEVKSSEPTED--VEPKEAEDDDTGPEEGSPPKEEK 343 >gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo sapiens] Length = 597 Score = 38.9 bits (89), Expect = 0.017 Identities = 62/286 (21%), Positives = 105/286 (36%), Gaps = 46/286 (16%) Query: 235 PDRRIKYEARLHVLKVNRQTVLEALQ----QLIRVTQPELIQTHKSQESQLPEESKSASN 290 P+ + Y R K ++E LQ Q+ T+ + + S ++SK + Sbjct: 252 PEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSKDSDF 311 Query: 291 KSPLVLEANRAPAASE--GNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLN---- 344 L ++AP E D + EAA S + AP+ N V++ P + Sbjct: 312 WKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEE 371 Query: 345 ---GVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDY 401 G I Q P + A+ P +E E R R + +DED+ Sbjct: 372 LKGGTKKGKPNIGQEQPV----DDAAEVPQREPEKERGDPERQR-----EMEEEEDEDED 422 Query: 402 EDDEEDDVQ---------------NTNSALRYKGKGTGKPGALSGSADGQLSVLQ-PNTI 445 ED++ED+ Q + LR + + P L ++ ++L +T+ Sbjct: 423 EDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTL 482 Query: 446 NVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNE 491 N L ++L+E Q + K VP PSP P+ + Sbjct: 483 NKLIKRLEEKQSPELVKKHKKKR--------VVPKKPPPSPQPTGK 520 >gi|91208420 bassoon protein [Homo sapiens] Length = 3926 Score = 38.9 bits (89), Expect = 0.017 Identities = 52/202 (25%), Positives = 74/202 (36%), Gaps = 38/202 (18%) Query: 414 SALRYKG-KGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAG 472 S L+ KG +G G+P SG + S L + L K K L KT S Sbjct: 551 SPLKQKGPQGLGQP---SGPLPAKASPLSTKA-SPLPSKASPQAKPLRASEPSKTPSSVQ 606 Query: 473 SPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLF 532 VPT ++P P P E+T T + ++S +R A P P K Sbjct: 607 EKKTRVPTKAEPMPKPPPETTPTPA------TPKVKSGVRRAEPATPVVKAVPEAPK--G 658 Query: 533 GEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGS 592 GE + L+ ++D SP +L++ G S I S Sbjct: 659 GEAEDLVGKP---------------------YSQDASRSPQSLSDTGYSSD----GISSS 693 Query: 593 QGSSSPVEKEVVEATDSREKTG 614 Q + V ++ VE DS TG Sbjct: 694 QSEITGVVQQEVEQLDSAGVTG 715 >gi|148612857 sickle tail isoform 3 [Homo sapiens] Length = 1309 Score = 38.9 bits (89), Expect = 0.017 Identities = 68/320 (21%), Positives = 111/320 (34%), Gaps = 41/320 (12%) Query: 315 EAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQR---LPAFLDNHNYAKSPM 371 E G + P PP + L PGS L R + A + + SP Sbjct: 1003 EKLGGKSPPPPPPPPRRSYL----PGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQ 1058 Query: 372 QEEEDLAAGVGRSR-VPVRPPQQYSDDEDDYEDDEEDD-----VQNTNSA-----LRYKG 420 A S P PP S +D+ E++EE D +Q ++ A + Sbjct: 1059 TRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPM 1118 Query: 421 KGTGKPGALSGSADGQLSVLQ-PNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVP 479 +PG L G+ S LQ P K+S D + PA +P Sbjct: 1119 SAKNRPGTL--DKPGKQSKLQDPRQYRQANGSAKKSGGDFK-------PTSPSLPASKIP 1169 Query: 480 THSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLL 539 S PS S+ ++ + + N P P ++NP P + +H + ++ + L Sbjct: 1170 ALS-PSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSL 1228 Query: 540 RVDCIRYNRAVRDL--GPVISTG------LLHLAEDGVLSPLALTEGGKGS----SPSIR 587 + + + L P G + S ++L +G KG+ +PS+ Sbjct: 1229 KFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLT 1288 Query: 588 PIQGSQGSSSPVEKEVVEAT 607 + GSSS + T Sbjct: 1289 SYKAQNGSSSKATPSTAKET 1308 >gi|148612813 sickle tail isoform 2 [Homo sapiens] Length = 1264 Score = 38.9 bits (89), Expect = 0.017 Identities = 68/320 (21%), Positives = 111/320 (34%), Gaps = 41/320 (12%) Query: 315 EAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQR---LPAFLDNHNYAKSPM 371 E G + P PP + L PGS L R + A + + SP Sbjct: 958 EKLGGKSPPPPPPPPRRSYL----PGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQ 1013 Query: 372 QEEEDLAAGVGRSR-VPVRPPQQYSDDEDDYEDDEEDD-----VQNTNSA-----LRYKG 420 A S P PP S +D+ E++EE D +Q ++ A + Sbjct: 1014 TRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPM 1073 Query: 421 KGTGKPGALSGSADGQLSVLQ-PNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVP 479 +PG L G+ S LQ P K+S D + PA +P Sbjct: 1074 SAKNRPGTL--DKPGKQSKLQDPRQYRQANGSAKKSGGDFK-------PTSPSLPASKIP 1124 Query: 480 THSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLL 539 S PS S+ ++ + + N P P ++NP P + +H + ++ + L Sbjct: 1125 ALS-PSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSL 1183 Query: 540 RVDCIRYNRAVRDL--GPVISTG------LLHLAEDGVLSPLALTEGGKGS----SPSIR 587 + + + L P G + S ++L +G KG+ +PS+ Sbjct: 1184 KFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLT 1243 Query: 588 PIQGSQGSSSPVEKEVVEAT 607 + GSSS + T Sbjct: 1244 SYKAQNGSSSKATPSTAKET 1263 >gi|116089335 BR serine/threonine kinase 2 [Homo sapiens] Length = 668 Score = 38.5 bits (88), Expect = 0.022 Identities = 46/200 (23%), Positives = 73/200 (36%), Gaps = 11/200 (5%) Query: 324 PSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGR 383 P P K ++ P SL + P+ + L F D + + + EEE+ + Sbjct: 279 PEQPIPRKVQIRSLP---SLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYF 335 Query: 384 SRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPN 443 + + +DED +E D + + G +P S P Sbjct: 336 LLLDRKERYPSQEDEDLPPRNEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTDGGSPV 395 Query: 444 TINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHS-QPSPTPSNESTDTASEIGSA 502 E + Q+ SI SGA S P S + +P PS + + G+ Sbjct: 396 PARRAIEMAQHGQRSRSI-------SGASSGLSTSPLSSPRVTPHPSPRGSPLPTPKGTP 448 Query: 503 FNSPLRSPIRSANPTRPSSP 522 ++P SP + NPT PSSP Sbjct: 449 VHTPKESPAGTPNPTPPSSP 468 >gi|39995080 hypothetical protein LOC79567 [Homo sapiens] Length = 1219 Score = 38.1 bits (87), Expect = 0.029 Identities = 72/330 (21%), Positives = 115/330 (34%), Gaps = 54/330 (16%) Query: 311 DGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSP 370 + + EA G + A SPP P + +G HP+P P PA H+ S Sbjct: 462 EASVEAVGPESLAWGPSPPTHP--------APTHGEHPSPVP-----PALDPGHSATSST 508 Query: 371 MQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQ---NTNSALRYKGKGT--GK 425 + V S P P + D D ++ +T + Y T Sbjct: 509 L----GTTGSVPTSTDPA--PSAHLDSVHKSTDSGPSELPGPTHTTTGSTYSAITTTHSA 562 Query: 426 PGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPS 485 P L+ + G +T + L + L+I ++T++ PTH+ PS Sbjct: 563 PSPLTHTTTG-------STHKPIISTLTTTGPTLNIIGPVQTTTS--------PTHTMPS 607 Query: 486 PTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIR 545 PT + S S SP +P + T S P T+ + G L++ Sbjct: 608 PTHTTASPTHTS------TSPTHTPTSPTHKTSMSPPTTTSPTPSGMG----LVQTATSP 657 Query: 546 YNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVE 605 + P S L++++ L L+ K S P++ P S S PV + Sbjct: 658 THPTTSPTHPTTSPILINVSPSTSLELATLSSPSKHSDPTL-PGTDSLPCSPPVSNSYTQ 716 Query: 606 ATDSREKTGMVRPG----EPLSGEKYSPKE 631 A +T P +PL+ P E Sbjct: 717 ADPMAPRTPHPSPAHSSRKPLTSPAPDPSE 746 >gi|38176300 nestin [Homo sapiens] Length = 1621 Score = 37.4 bits (85), Expect = 0.050 Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 16/121 (13%) Query: 394 YSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLK 453 ++D+E+ E+ EED + R G G PG+ GS LQ + + E L+ Sbjct: 1412 FADEEESGEEGEEDQEEG-----REPGAGRWGPGSSVGS-------LQALSSSQRGEFLE 1459 Query: 454 ESQKDLSIPLSIKTSSG-AGSPAVAVPTHSQPSPTPS---NESTDTASEIGSAFNSPLRS 509 +S+P AG+P A+ T SQ S PS ES + E PL Sbjct: 1460 SDSVSVSVPWDDSLRGAVAGAPKTALETESQDSAEPSGSEEESDPVSLEREDKVPGPLEI 1519 Query: 510 P 510 P Sbjct: 1520 P 1520 >gi|24431933 reticulon 4 isoform B [Homo sapiens] Length = 373 Score = 37.0 bits (84), Expect = 0.065 Identities = 36/143 (25%), Positives = 55/143 (38%), Gaps = 20/143 (13%) Query: 388 VRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINV 447 VR P+ ++E++ E+DE++D++ R KP A LS T Sbjct: 28 VREPEDEEEEEEEEEEDEDEDLEELEVLER-------KPAA-------GLSAAPVPTAPA 73 Query: 448 LAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPS--PTPSNESTDTASEIGSAFNS 505 L + D P G A V QPS P+P + + S + +A S Sbjct: 74 AGAPLMDFGNDFVPP----APRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVS 129 Query: 506 PLRSPIRSANPTRPSSPVTSHIS 528 P + P P RP P + +S Sbjct: 130 PSKLPEDDEPPARPPPPPPASVS 152 >gi|47519490 reticulon 4 isoform D [Homo sapiens] Length = 392 Score = 37.0 bits (84), Expect = 0.065 Identities = 36/143 (25%), Positives = 55/143 (38%), Gaps = 20/143 (13%) Query: 388 VRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINV 447 VR P+ ++E++ E+DE++D++ R KP A LS T Sbjct: 28 VREPEDEEEEEEEEEEDEDEDLEELEVLER-------KPAA-------GLSAAPVPTAPA 73 Query: 448 LAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPS--PTPSNESTDTASEIGSAFNS 505 L + D P G A V QPS P+P + + S + +A S Sbjct: 74 AGAPLMDFGNDFVPP----APRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVS 129 Query: 506 PLRSPIRSANPTRPSSPVTSHIS 528 P + P P RP P + +S Sbjct: 130 PSKLPEDDEPPARPPPPPPASVS 152 >gi|24431935 reticulon 4 isoform A [Homo sapiens] Length = 1192 Score = 37.0 bits (84), Expect = 0.065 Identities = 36/143 (25%), Positives = 55/143 (38%), Gaps = 20/143 (13%) Query: 388 VRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINV 447 VR P+ ++E++ E+DE++D++ R KP A LS T Sbjct: 28 VREPEDEEEEEEEEEEDEDEDLEELEVLER-------KPAA-------GLSAAPVPTAPA 73 Query: 448 LAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPS--PTPSNESTDTASEIGSAFNS 505 L + D P G A V QPS P+P + + S + +A S Sbjct: 74 AGAPLMDFGNDFVPP----APRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVS 129 Query: 506 PLRSPIRSANPTRPSSPVTSHIS 528 P + P P RP P + +S Sbjct: 130 PSKLPEDDEPPARPPPPPPASVS 152 >gi|119395716 forkhead box C1 [Homo sapiens] Length = 553 Score = 37.0 bits (84), Expect = 0.065 Identities = 83/344 (24%), Positives = 127/344 (36%), Gaps = 74/344 (21%) Query: 308 NHTDGAEEAAGSCAQAPS-HSPPNKPKLVVKPPGS-----------------SLNGVHPN 349 +H AE+ G A+A ++P +PK +VKPP S +LNG++ Sbjct: 48 SHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQF 107 Query: 350 PTPIVQRLPAFLDN---------HN------YAKSPMQEEEDLAAGVGRSRVPVRPPQQY 394 I+ R P + DN HN + K P +++ G+ P Y Sbjct: 108 ---IMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKP-----GKGSYWTLDPDSY 159 Query: 395 S--------------DDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVL 440 + +D +D EE D + G P A ADG Sbjct: 160 NMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKEP---PPPGRQPPPAPPEQADGNAPGP 216 Query: 441 QPNTINVLAEKLKESQ-KDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTA--S 497 QP + + K + PLS + G+GS A AVP P + S+ S+ ++ Sbjct: 217 QPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGS-AAAVPKIESPDSSSSSLSSGSSPPG 275 Query: 498 EIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVI 557 + SA L + P PS+P H F D+ + + + + + Sbjct: 276 SLPSARPLSLDGADSAPPPPAPSAPPPHHSQG--FSVDNIMTSL-----RGSPQSAAAEL 328 Query: 558 STGLLHLA----EDGVLSPLALTEGGKGSSPSIRPIQGSQGSSS 597 S+GLL A G+ PLAL G S S+ SQ SS+ Sbjct: 329 SSGLLASAAASSRAGIAPPLALGAYSPGQS-SLYSSPCSQTSSA 371 >gi|187960059 syndecan 3 [Homo sapiens] Length = 442 Score = 37.0 bits (84), Expect = 0.065 Identities = 32/132 (24%), Positives = 54/132 (40%), Gaps = 5/132 (3%) Query: 395 SDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKE 454 S D+D + DDE DD+ + S Y + +G A+ S D L+V + Sbjct: 64 SGDDDSFPDDELDDLY-SGSGSGYFEQESGIETAMRFSPDVALAVSTTPAVLPTTNIQPV 122 Query: 455 SQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSP----LRSP 510 +P T A SP V +PS + ST A+ ++ P + + Sbjct: 123 GTPFEELPSERPTLEPATSPLVVTEVPEEPSQRATTVSTTMATTAATSTGDPTVATVPAT 182 Query: 511 IRSANPTRPSSP 522 + +A P+ P++P Sbjct: 183 VATATPSTPAAP 194 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 36.6 bits (83), Expect = 0.085 Identities = 59/229 (25%), Positives = 81/229 (35%), Gaps = 45/229 (19%) Query: 317 AGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYA----KSPMQ 372 AG+ A+ P+ P L +PPGS P P P V PA L A + P+ Sbjct: 10 AGAAARTPAARAPGL--LTPRPPGS------PRPPPPVT--PAALRVLGAAGAVGRKPLA 59 Query: 373 EEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGK------- 425 E A G+G + +P P+ + N A R G G+ Sbjct: 60 ER---AGGIGGATIPESAPRA--------GPTRSAGTSSRNPASRPPASGRGERAPPAKN 108 Query: 426 --PGALS--GSADGQL--SVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVP 479 PG +S G A G L + + AE+ K P S+GA P Sbjct: 109 TSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG-P 167 Query: 480 THSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHIS 528 T PSP + S +E+G L P SA P P+ +S Sbjct: 168 TPGTPSPAMARRSRAAGTEVG------LPRPAPSARPRPPTEGPRKSVS 210 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 36.6 bits (83), Expect = 0.085 Identities = 59/229 (25%), Positives = 81/229 (35%), Gaps = 45/229 (19%) Query: 317 AGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYA----KSPMQ 372 AG+ A+ P+ P L +PPGS P P P V PA L A + P+ Sbjct: 10 AGAAARTPAARAPGL--LTPRPPGS------PRPPPPVT--PAALRVLGAAGAVGRKPLA 59 Query: 373 EEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGK------- 425 E A G+G + +P P+ + N A R G G+ Sbjct: 60 ER---AGGIGGATIPESAPRA--------GPTRSAGTSSRNPASRPPASGRGERAPPAKN 108 Query: 426 --PGALS--GSADGQL--SVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVP 479 PG +S G A G L + + AE+ K P S+GA P Sbjct: 109 TSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG-P 167 Query: 480 THSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHIS 528 T PSP + S +E+G L P SA P P+ +S Sbjct: 168 TPGTPSPAMARRSRAAGTEVG------LPRPAPSARPRPPTEGPRKSVS 210 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 36.6 bits (83), Expect = 0.085 Identities = 55/220 (25%), Positives = 80/220 (36%), Gaps = 36/220 (16%) Query: 317 AGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYA----KSPMQ 372 AG+ A+ P+ P L +PPGS P P P V PA L A + P+ Sbjct: 10 AGAAARTPAARAPGL--LTPRPPGS------PRPPPPVT--PAALRVLGAAGAVGRKPLA 59 Query: 373 EEEDLAAGVGRSRVPVRPPQ----QYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGA 428 E A G+G + +P P+ + S + +NT+ PG Sbjct: 60 ER---AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPG------PVSSPGR 110 Query: 429 LSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTP 488 SG+ + L + + AE+ K P S+GA PT PSP Sbjct: 111 ASGTT--RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG-PTPGTPSPAM 167 Query: 489 SNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHIS 528 + S +E+G L P SA P P+ +S Sbjct: 168 ARRSRAAGTEVG------LPRPAPSARPRPPTEGPRKSVS 201 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 36.6 bits (83), Expect = 0.085 Identities = 31/147 (21%), Positives = 54/147 (36%), Gaps = 22/147 (14%) Query: 396 DDEDDYEDDE--------------------EDDVQNTNSALRYKGKGTGKPGALSGSADG 435 D+EDD ED+E ED+ +++S G+ + S S Sbjct: 977 DEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESS 1036 Query: 436 QLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDT 495 S ++ + + S + S + A P+ + P P PTP+ Sbjct: 1037 SSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPV 1096 Query: 496 ASEIGSAFNSPLRSPIRSANPTRPSSP 522 + + +PL P + A+P RP+ P Sbjct: 1097 PERVAGSPVTPL--PEQEASPARPAGP 1121 >gi|109637791 transcription factor-like nuclear regulator [Homo sapiens] Length = 2624 Score = 36.6 bits (83), Expect = 0.085 Identities = 37/151 (24%), Positives = 64/151 (42%), Gaps = 36/151 (23%) Query: 386 VPVRPPQQYSDDEDDYEDDEEDD-----VQNTNSALRYKGKGTGKPGALSGSADGQLSVL 440 V +R Q+ DD DD+E D E++ + N A + G P +S + + L Sbjct: 1866 VTLRASQEEDDDADDFESDYEEESYHLAPEEVNKAPVFVPVGLRSPEPVSAQIEETMEEL 1925 Query: 441 Q------------------PNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHS 482 + PNT +V E++K+ +++LS+P + TS H Sbjct: 1926 EITVNVPDVGCIAVVEHELPNT-DVTTEEMKQ-EENLSVPFEMTTSE-----------HI 1972 Query: 483 QPSPTPSNESTDTASEIGSAFNSPLRSPIRS 513 Q P ++ ST+ A + + + L+S I S Sbjct: 1973 QDEPGTNDGSTEAAITLLTMGDLVLQSEISS 2003 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 36.2 bits (82), Expect = 0.11 Identities = 59/266 (22%), Positives = 95/266 (35%), Gaps = 23/266 (8%) Query: 282 PEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGS 341 PEE S + P E +PAA+ EE A A P+ P P V P Sbjct: 1101 PEEPTSPAAAVPTP-EEPASPAAA----VPTPEEPASPAAAVPTPEEPAFPAPAVPTPEE 1155 Query: 342 SLNGVHPNPTPIVQRLPAFL-----DNHNYAK--SPMQEEEDLAAGVGRSRVPVRPPQQY 394 S + PTP PA ++ ++A + ++E AA V V +++ Sbjct: 1156 SASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEF 1215 Query: 395 SDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGA---LSGSADGQLSVLQPNTINVLAEK 451 + EE + +A+ + T A L +VL P ++ A Sbjct: 1216 TSPAASVPTSEEP--ASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAAS 1273 Query: 452 LKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPS------PTPSNESTDTASEIGSAFNS 505 + ++ S ++ SPA AVPT + PTP + A+ S Sbjct: 1274 VPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVS 1333 Query: 506 PLRSPIRSANPTRPSSPVTSHISKVL 531 P+ P + S P++ + VL Sbjct: 1334 PIGVPFLGVSAHTDSVPISEEGTPVL 1359 Score = 32.3 bits (72), Expect = 1.6 Identities = 27/108 (25%), Positives = 42/108 (38%), Gaps = 6/108 (5%) Query: 423 TGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHS 482 T + G G +V P + A ++ ++ S ++ T SPA AVPT Sbjct: 965 TEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE 1024 Query: 483 QP-SPT----PSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTS 525 +P SP P E T A+ + + P P P+SP + Sbjct: 1025 EPTSPAAAVPPPEEPTSPAAAVPTP-EEPTSPAAAVPTPEEPTSPAAA 1071 >gi|119943102 CREB binding protein isoform b [Homo sapiens] Length = 2404 Score = 36.2 bits (82), Expect = 0.11 Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 20/105 (19%) Query: 422 GTGKPGALSGSADGQL-SVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPT 480 G G+P A +G + GQ+ PN +N+L + + L P P P Sbjct: 771 GMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQ----LPCP-----------PVTQSPL 815 Query: 481 HSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTS 525 H PTP ST P +P + A PT+PS+PV+S Sbjct: 816 H----PTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSS 856 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.131 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 30,834,147 Number of Sequences: 37866 Number of extensions: 1595608 Number of successful extensions: 8584 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 223 Number of HSP's that attempted gapping in prelim test: 7800 Number of HSP's gapped (non-prelim): 889 length of query: 729 length of database: 18,247,518 effective HSP length: 110 effective length of query: 619 effective length of database: 14,082,258 effective search space: 8716917702 effective search space used: 8716917702 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.