Search of human proteins with 46249393

Search of human proteins with 46249393

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46249393 ras homolog gene family, member G [Homo sapiens]
         (191 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46249393 ras homolog gene family, member G [Homo sapiens]          395   e-111
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra...   281   2e-76
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil...   276   8e-75
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi...   275   2e-74
gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra...   270   7e-73
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]           252   2e-67
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]            252   2e-67
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]           245   2e-65
gi|50263042 ras-like protein TC10 [Homo sapiens]                      218   3e-57
gi|10835049 ras homolog gene family, member A [Homo sapiens]          216   1e-56
gi|111494251 ras homolog gene family, member C precursor [Homo s...   214   4e-56
gi|111494248 ras homolog gene family, member C precursor [Homo s...   214   4e-56
gi|28395033 ras homolog gene family, member C precursor [Homo sa...   214   4e-56
gi|4757764 ras homolog gene family, member B [Homo sapiens]           202   1e-52
gi|16903164 ras homolog gene family, member J [Homo sapiens]          202   2e-52
gi|11034843 ras homolog gene family, member U [Homo sapiens]          195   2e-50
gi|229577148 ras homolog gene family, member V [Homo sapiens]         188   2e-48
gi|7656900 ras homolog D [Homo sapiens]                               185   2e-47
gi|38016957 ras homolog gene family, member F [Homo sapiens]          182   2e-46
gi|4885069 ras homolog gene family, member E [Homo sapiens]           166   9e-42
gi|4885581 Rho family GTPase 2 [Homo sapiens]                         158   2e-39
gi|4757770 ras homolog gene family, member H [Homo sapiens]           145   3e-35
gi|7657514 GTP-binding protein RHO6 [Homo sapiens]                    141   4e-34
gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo...   125   2e-29
gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo...   125   2e-29
gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo...   125   2e-29
gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]        123   1e-28
gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ...    99   3e-21
gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is...    99   3e-21
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]        93   1e-19

>gi|46249393 ras homolog gene family, member G [Homo sapiens]
          Length = 191

 Score =  395 bits (1016), Expect = e-111
 Identities = 191/191 (100%), Positives = 191/191 (100%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG
Sbjct: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
           QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR
Sbjct: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120

Query: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 180
           AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT
Sbjct: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 180

Query: 181 PIKRGRSCILL 191
           PIKRGRSCILL
Sbjct: 181 PIKRGRSCILL 191


>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
           [Homo sapiens]
          Length = 192

 Score =  281 bits (719), Expect = 2e-76
 Identities = 138/192 (71%), Positives = 158/192 (82%), Gaps = 1/192 (0%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           MQ+IKCVVVGDGAVGKTCLLI YTTNAFP EYIPTVFDNYSA   VDG+ VNL LWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
           QE+YDRLR LSYPQT+VF+ICFS+ SP S+ENVR KW+PEV HHCP+ PI+LVGTK DLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR 120

Query: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 180
              DT+ +LKE+   PIT  QG A+AK+I AV+YLECSAL Q G+K VF EA+RAVL P 
Sbjct: 121 DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP 180

Query: 181 PI-KRGRSCILL 191
           P+ KR R C+LL
Sbjct: 181 PVKKRKRKCLLL 192


>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
           small GTP binding protein Rac3) [Homo sapiens]
          Length = 192

 Score =  276 bits (706), Expect = 8e-75
 Identities = 134/189 (70%), Positives = 156/189 (82%), Gaps = 1/189 (0%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           MQ+IKCVVVGDGAVGKTCLLI YTTNAFP EYIPTVFDNYSA   VDG+ VNL LWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
           QE+YDRLR LSYPQT+VF+ICFS+ SP S+ENVR KW+PEV HHCP  PILLVGTK DLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLR 120

Query: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 180
              DT+ RL+++  APIT  QG A+A++I +V+YLECSAL Q G+K VF EA+RAVL P 
Sbjct: 121 DDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPP 180

Query: 181 PIKR-GRSC 188
           P+K+ G+ C
Sbjct: 181 PVKKPGKKC 189


>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
           sapiens]
          Length = 192

 Score =  275 bits (703), Expect = 2e-74
 Identities = 137/192 (71%), Positives = 155/192 (80%), Gaps = 1/192 (0%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           MQ+IKCVVVGDGAVGKTCLLI YTTNAFP EYIPTVFDNYSA   VD + VNL LWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 60

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
           QE+YDRLR LSYPQT+VF+ICFS+ SP SYENVR KW PEV HHCP  PI+LVGTK DLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 120

Query: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 180
              DT+ +LKE+  APIT  QG ALAK+I +V+YLECSAL Q G+K VF EA+RAVL P 
Sbjct: 121 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 180

Query: 181 PIK-RGRSCILL 191
           P + + R+C LL
Sbjct: 181 PTRQQKRACSLL 192


>gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b
           [Homo sapiens]
          Length = 211

 Score =  270 bits (689), Expect = 7e-73
 Identities = 138/211 (65%), Positives = 158/211 (74%), Gaps = 20/211 (9%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           MQ+IKCVVVGDGAVGKTCLLI YTTNAFP EYIPTVFDNYSA   VDG+ VNL LWDTAG
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 60

Query: 61  QEEYDRLRTLSYPQT-------------------NVFVICFSIASPPSYENVRHKWHPEV 101
           QE+YDRLR LSYPQT                   +VF+ICFS+ SP S+ENVR KW+PEV
Sbjct: 61  QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV 120

Query: 102 CHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQ 161
            HHCP+ PI+LVGTK DLR   DT+ +LKE+   PIT  QG A+AK+I AV+YLECSAL 
Sbjct: 121 RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT 180

Query: 162 QDGVKEVFAEAVRAVLNPTPI-KRGRSCILL 191
           Q G+K VF EA+RAVL P P+ KR R C+LL
Sbjct: 181 QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL 211


>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  252 bits (643), Expect = 2e-67
 Identities = 116/191 (60%), Positives = 143/191 (74%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           MQ+IKCVVVGDGAVGKTCLLI YTTN FP EY+PTVFDNY+    + G    L L+DTAG
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 60

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
           QE+YDRLR LSYPQT+VF++CFS+ SP S+ENV+ KW PE+ HHCP  P LLVGT+ DLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 120

Query: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 180
             P T+ +L +  Q PITP+  + LA+ + AV+Y+ECSAL Q G+K VF EA+ A L P 
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP 180

Query: 181 PIKRGRSCILL 191
             K+ R C+LL
Sbjct: 181 EPKKSRRCVLL 191


>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  252 bits (643), Expect = 2e-67
 Identities = 116/191 (60%), Positives = 143/191 (74%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           MQ+IKCVVVGDGAVGKTCLLI YTTN FP EY+PTVFDNY+    + G    L L+DTAG
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 60

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
           QE+YDRLR LSYPQT+VF++CFS+ SP S+ENV+ KW PE+ HHCP  P LLVGT+ DLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 120

Query: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 180
             P T+ +L +  Q PITP+  + LA+ + AV+Y+ECSAL Q G+K VF EA+ A L P 
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP 180

Query: 181 PIKRGRSCILL 191
             K+ R C+LL
Sbjct: 181 EPKKSRRCVLL 191


>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
          Length = 191

 Score =  245 bits (625), Expect = 2e-65
 Identities = 113/190 (59%), Positives = 140/190 (73%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           MQ+IKCVVVGDGAVGKTCLLI YTTN FP EY+PTVFDNY+    + G    L L+DTAG
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 60

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
           QE+YDRLR LSYPQT+VF++CFS+ SP S+ENV+ KW PE+ HHCP  P LLVGT+ DLR
Sbjct: 61  QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 120

Query: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 180
             P T+ +L +  Q PITP+  + LA+ + AV+Y+ECSAL Q G+K VF EA+ A L P 
Sbjct: 121 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEPP 180

Query: 181 PIKRGRSCIL 190
             +  R C +
Sbjct: 181 ETQPKRKCCI 190


>gi|50263042 ras-like protein TC10 [Homo sapiens]
          Length = 205

 Score =  218 bits (554), Expect = 3e-57
 Identities = 108/190 (56%), Positives = 139/190 (73%), Gaps = 4/190 (2%)

Query: 4   IKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEE 63
           +KCVVVGDGAVGKTCLL+ Y  +AFP+EY+PTVFD+Y+    V G+   L L+DTAGQE+
Sbjct: 10  LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQED 69

Query: 64  YDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQP 123
           YDRLR LSYP T+VF+ICFS+ +P S++NV+ +W PE+  + P+VP LL+GT+ DLR  P
Sbjct: 70  YDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDP 129

Query: 124 DTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNP---T 180
            TL RL +  + PI  +QGQ LAK+I A  Y+ECSAL Q G+K VF EA+ A+L P   T
Sbjct: 130 KTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHT 189

Query: 181 PIKR-GRSCI 189
             KR G  CI
Sbjct: 190 VKKRIGSRCI 199


>gi|10835049 ras homolog gene family, member A [Homo sapiens]
          Length = 193

 Score =  216 bits (550), Expect = 1e-56
 Identities = 104/187 (55%), Positives = 132/187 (70%)

Query: 5   KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEY 64
           K V+VGDGA GKTCLLI ++ + FP+ Y+PTVF+NY A   VDG+ V L LWDTAGQE+Y
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPD 124
           DRLR LSYP T+V ++CFSI SP S EN+  KW PEV H CP+VPI+LVG KKDLR    
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126

Query: 125 TLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKR 184
           T R L +  Q P+ P++G+ +A +I A  Y+ECSA  +DGV+EVF  A RA L     K+
Sbjct: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKK 186

Query: 185 GRSCILL 191
              C++L
Sbjct: 187 KSGCLVL 193


>gi|111494251 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  214 bits (545), Expect = 4e-56
 Identities = 105/187 (56%), Positives = 131/187 (70%)

Query: 5   KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEY 64
           K V+VGDGA GKTCLLI ++ + FP+ Y+PTVF+NY A   VDG+ V L LWDTAGQE+Y
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPD 124
           DRLR LSYP T+V ++CFSI SP S EN+  KW PEV H CP+VPI+LVG KKDLR    
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 125 TLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKR 184
           T R L +  Q P+  ++G+ +A +I A  YLECSA  ++GV+EVF  A RA L     KR
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKR 186

Query: 185 GRSCILL 191
            R C +L
Sbjct: 187 RRGCPIL 193


>gi|111494248 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  214 bits (545), Expect = 4e-56
 Identities = 105/187 (56%), Positives = 131/187 (70%)

Query: 5   KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEY 64
           K V+VGDGA GKTCLLI ++ + FP+ Y+PTVF+NY A   VDG+ V L LWDTAGQE+Y
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPD 124
           DRLR LSYP T+V ++CFSI SP S EN+  KW PEV H CP+VPI+LVG KKDLR    
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 125 TLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKR 184
           T R L +  Q P+  ++G+ +A +I A  YLECSA  ++GV+EVF  A RA L     KR
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKR 186

Query: 185 GRSCILL 191
            R C +L
Sbjct: 187 RRGCPIL 193


>gi|28395033 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  214 bits (545), Expect = 4e-56
 Identities = 105/187 (56%), Positives = 131/187 (70%)

Query: 5   KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEY 64
           K V+VGDGA GKTCLLI ++ + FP+ Y+PTVF+NY A   VDG+ V L LWDTAGQE+Y
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPD 124
           DRLR LSYP T+V ++CFSI SP S EN+  KW PEV H CP+VPI+LVG KKDLR    
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 125 TLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKR 184
           T R L +  Q P+  ++G+ +A +I A  YLECSA  ++GV+EVF  A RA L     KR
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKR 186

Query: 185 GRSCILL 191
            R C +L
Sbjct: 187 RRGCPIL 193


>gi|4757764 ras homolog gene family, member B [Homo sapiens]
          Length = 196

 Score =  202 bits (515), Expect = 1e-52
 Identities = 98/173 (56%), Positives = 121/173 (69%)

Query: 5   KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEY 64
           K VVVGDGA GKTCLLI ++ + FP+ Y+PTVF+NY A   VDG+ V L LWDTAGQE+Y
Sbjct: 7   KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 65  DRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPD 124
           DRLR LSYP T+V ++CFS+ SP S EN+  KW PEV H CP+VPI+LV  KKDLR+   
Sbjct: 67  DRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEH 126

Query: 125 TLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVL 177
               L    Q P+    G+A+A +I A  YLECSA  ++GV+EVF  A RA L
Sbjct: 127 VRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAAL 179


>gi|16903164 ras homolog gene family, member J [Homo sapiens]
          Length = 214

 Score =  202 bits (513), Expect = 2e-52
 Identities = 101/189 (53%), Positives = 131/189 (69%), Gaps = 4/189 (2%)

Query: 4   IKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEE 63
           +KCVVVGDGAVGKTCLL+ Y  +AFP+EY+PTVFD+Y+    V G+   L L+DTAGQE+
Sbjct: 22  LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQED 81

Query: 64  YDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQP 123
           Y++LR LSYP T+VF+ICFS+ +P SY NV+ +W PE+    P VP +L+GT+ DLR  P
Sbjct: 82  YNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDP 141

Query: 124 DTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIK 183
            TL RL    + P+T + G  LAK I A  YLECSAL Q G+K VF EA+  + +P   K
Sbjct: 142 KTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKK 201

Query: 184 R----GRSC 188
           +    G SC
Sbjct: 202 KRCSEGHSC 210


>gi|11034843 ras homolog gene family, member U [Homo sapiens]
          Length = 258

 Score =  195 bits (495), Expect = 2e-50
 Identities = 91/174 (52%), Positives = 122/174 (70%)

Query: 2   QSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQ 61
           + +KCV+VGDGAVGKT L++ YTTN +P EYIPT FDN+SA  +VDGR V L L DTAGQ
Sbjct: 48  RGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQ 107

Query: 62  EEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRA 121
           +E+D+LR L Y  T++F++CFS+ SP S++NV  KW PE+  HCP  PI+LVGT+ DLR 
Sbjct: 108 DEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLRE 167

Query: 122 QPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRA 175
               L  L +  + P+  +  +  A++I A  Y+ECSAL Q  +KEVF  A+ A
Sbjct: 168 DVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVA 221


>gi|229577148 ras homolog gene family, member V [Homo sapiens]
          Length = 236

 Score =  188 bits (478), Expect = 2e-48
 Identities = 89/175 (50%), Positives = 119/175 (68%), Gaps = 1/175 (0%)

Query: 4   IKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEE 63
           IKCV+VGDGAVGK+ L++ YT N +P  Y PT  D +S Q  VDG  V + LWDTAGQE+
Sbjct: 32  IKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQED 91

Query: 64  YDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQP 123
           +DRLR+L YP T+VF+ CFS+  P S++N+  KW PE+  H P  P+LLVGT+ DLR   
Sbjct: 92  FDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDV 151

Query: 124 DTLRRLKEQG-QAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVL 177
           + L +L + G + P+   Q Q LA++I A  YLECSAL Q  +KEVF  A+ + +
Sbjct: 152 NVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAI 206


>gi|7656900 ras homolog D [Homo sapiens]
          Length = 210

 Score =  185 bits (469), Expect = 2e-47
 Identities = 86/187 (45%), Positives = 122/187 (65%), Gaps = 4/187 (2%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           ++S+K V+VGDG  GKT LL+ +   AFP+ Y PTVF+ Y     V G+ V+L++WDTAG
Sbjct: 15  VRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDTAG 74

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
           Q++YDRLR L YP  +V ++CF + SP S++N+ ++W+PEV H C  VPI++VG K DLR
Sbjct: 75  QDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLR 134

Query: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 180
                + +L+  G  P+T  +GQ +A+ + AV YLECSA   D V  VF EA    L+  
Sbjct: 135 KDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDNVHAVFQEAAEVALS-- 192

Query: 181 PIKRGRS 187
              RGR+
Sbjct: 193 --SRGRN 197


>gi|38016957 ras homolog gene family, member F [Homo sapiens]
          Length = 211

 Score =  182 bits (461), Expect = 2e-46
 Identities = 89/194 (45%), Positives = 126/194 (64%), Gaps = 4/194 (2%)

Query: 2   QSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQ 61
           + +K V+VGDG  GKT LL+ Y+  +FP+ Y P+VF+ Y+A   V  + V LNL+DTAGQ
Sbjct: 18  KELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQ 77

Query: 62  EEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRA 121
           E+YDRLR LSY  T++ +IC+ + +P SY+NV  KW PEV H C  +P++L+G K DLR 
Sbjct: 78  EDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRK 137

Query: 122 QPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTP 181
             + LR+L+     PIT  QG +  +QI A  YLECSA  ++ V++VF EA +  L+   
Sbjct: 138 DKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALK 197

Query: 182 ----IKRGRSCILL 191
                K+ R C+LL
Sbjct: 198 KAQRQKKRRLCLLL 211


>gi|4885069 ras homolog gene family, member E [Homo sapiens]
          Length = 244

 Score =  166 bits (421), Expect = 9e-42
 Identities = 84/191 (43%), Positives = 120/191 (62%), Gaps = 5/191 (2%)

Query: 2   QSIKC--VVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTA 59
           Q++KC  VVVGD   GKT LL  +  + FP+ Y+PTVF+NY+A   +D + + L+LWDT+
Sbjct: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79

Query: 60  GQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDL 119
           G   YD +R LSYP ++  +ICF I+ P + ++V  KW  E+   CP+  +LLVG K DL
Sbjct: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139

Query: 120 RAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQ-QDGVKEVFAEAVRAVLN 178
           R    TL  L    Q P++  QG  +AKQI A  Y+ECSALQ ++ V+++F  A  A +N
Sbjct: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVN 199

Query: 179 PT--PIKRGRS 187
            T   +KR +S
Sbjct: 200 KTNKNVKRNKS 210


>gi|4885581 Rho family GTPase 2 [Homo sapiens]
          Length = 227

 Score =  158 bits (400), Expect = 2e-39
 Identities = 77/174 (44%), Positives = 109/174 (62%), Gaps = 1/174 (0%)

Query: 5   KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEY 64
           K VVVGD   GKT LL  +  +A+P  Y+PTVF+NY+A   +D R + LN+WDT+G   Y
Sbjct: 9   KIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYY 68

Query: 65  DRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPD 124
           D +R L+YP ++  +ICF I+ P + ++V  KW  E    CP+  ++LVG K D+R    
Sbjct: 69  DNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLA 128

Query: 125 TLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQD-GVKEVFAEAVRAVL 177
           TLR L +Q   P+T +QG  LAKQ+ AV Y+ECS+   +  V++VF  A  A L
Sbjct: 129 TLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASL 182


>gi|4757770 ras homolog gene family, member H [Homo sapiens]
          Length = 191

 Score =  145 bits (365), Expect = 3e-35
 Identities = 72/178 (40%), Positives = 111/178 (62%), Gaps = 7/178 (3%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           + SIKCV+VGD AVGKT LL+ +T+  FP+ Y PTV++N      +DG  ++L LWDTAG
Sbjct: 2   LSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAG 61

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 120
            + +  +R LSY Q +V ++C+S+A+  S+ N+++KW  E+  + P  P+L+V T+ D  
Sbjct: 62  NDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTD-- 119

Query: 121 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLN 178
                 R +     + +   +G+ LA+ + A  YLECSAL   GV++VF  AVR  +N
Sbjct: 120 -----QREMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVN 172


>gi|7657514 GTP-binding protein RHO6 [Homo sapiens]
          Length = 232

 Score =  141 bits (355), Expect = 4e-34
 Identities = 72/180 (40%), Positives = 106/180 (58%), Gaps = 2/180 (1%)

Query: 5   KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEY 64
           K V+VGD   GKT +L     + +P+ Y+PTVF+NY+A    + + V L+LWDT+G   Y
Sbjct: 15  KLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYY 74

Query: 65  DRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPD 124
           D +R L Y  ++  ++CF I+ P + ++   KW  E+  +CP   +LL+G K DLR    
Sbjct: 75  DNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLS 134

Query: 125 TLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSAL-QQDGVKEVFAEAVRAVLN-PTPI 182
           TL  L  Q QAPI+ +QG A+AKQ+ A  YLE SA   +  +  +F  A    LN P+P+
Sbjct: 135 TLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLNKPSPL 194


>gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 727

 Score =  125 bits (314), Expect = 2e-29
 Identities = 77/200 (38%), Positives = 115/200 (57%), Gaps = 26/200 (13%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEY------IPTVF--DNYS--------AQS 44
           +++IKCVVVGD AVGKT L+     NA   +Y      +PTV+  D Y         ++ 
Sbjct: 12  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71

Query: 45  AVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH 104
            VD  +V+L LWDT G    DR    +Y +++V V+CFSIA+P S  +V+  W+PE+ H 
Sbjct: 72  VVDDVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 129

Query: 105 CPDVPILLVGTKKDLR-AQPDTLRRLKEQGQAPI------TPQQGQALAKQIHAVRYLEC 157
           CP  P++LVG + DLR A  + + R +     PI       P++G+ +AK++  + Y E 
Sbjct: 130 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 188

Query: 158 SALQQDGVKEVFAEAVRAVL 177
           S + Q G+K+VF  A+RA L
Sbjct: 189 SVVAQFGIKDVFDNAIRAAL 208


>gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 734

 Score =  125 bits (314), Expect = 2e-29
 Identities = 77/200 (38%), Positives = 115/200 (57%), Gaps = 26/200 (13%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEY------IPTVF--DNYS--------AQS 44
           +++IKCVVVGD AVGKT L+     NA   +Y      +PTV+  D Y         ++ 
Sbjct: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78

Query: 45  AVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH 104
            VD  +V+L LWDT G    DR    +Y +++V V+CFSIA+P S  +V+  W+PE+ H 
Sbjct: 79  VVDDVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 136

Query: 105 CPDVPILLVGTKKDLR-AQPDTLRRLKEQGQAPI------TPQQGQALAKQIHAVRYLEC 157
           CP  P++LVG + DLR A  + + R +     PI       P++G+ +AK++  + Y E 
Sbjct: 137 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 195

Query: 158 SALQQDGVKEVFAEAVRAVL 177
           S + Q G+K+VF  A+RA L
Sbjct: 196 SVVAQFGIKDVFDNAIRAAL 215


>gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 749

 Score =  125 bits (314), Expect = 2e-29
 Identities = 77/200 (38%), Positives = 115/200 (57%), Gaps = 26/200 (13%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEY------IPTVF--DNYS--------AQS 44
           +++IKCVVVGD AVGKT L+     NA   +Y      +PTV+  D Y         ++ 
Sbjct: 34  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93

Query: 45  AVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH 104
            VD  +V+L LWDT G    DR    +Y +++V V+CFSIA+P S  +V+  W+PE+ H 
Sbjct: 94  VVDDVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 151

Query: 105 CPDVPILLVGTKKDLR-AQPDTLRRLKEQGQAPI------TPQQGQALAKQIHAVRYLEC 157
           CP  P++LVG + DLR A  + + R +     PI       P++G+ +AK++  + Y E 
Sbjct: 152 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 210

Query: 158 SALQQDGVKEVFAEAVRAVL 177
           S + Q G+K+VF  A+RA L
Sbjct: 211 SVVAQFGIKDVFDNAIRAAL 230


>gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]
          Length = 696

 Score =  123 bits (308), Expect = 1e-28
 Identities = 76/200 (38%), Positives = 113/200 (56%), Gaps = 26/200 (13%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEY------IPTVF--DNYS--------AQS 44
           +++IKCVVVGD AVGKT L+     N    +Y      +PTV+  D Y         ++ 
Sbjct: 12  VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71

Query: 45  AVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH 104
            VD  +V+L LWDT G    DR    +Y +++V V+CFSIA+P S  +V+  W+PE+ H 
Sbjct: 72  VVDEVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHF 129

Query: 105 CPDVPILLVGTKKDLR-AQPDTLRRLKEQGQAPI------TPQQGQALAKQIHAVRYLEC 157
           CP  P++LVG + DLR A  + + R +     PI       P++G+ +AK++  + Y E 
Sbjct: 130 CPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYET 188

Query: 158 SALQQDGVKEVFAEAVRAVL 177
           S   Q G+K+VF  A+RA L
Sbjct: 189 SVFDQFGIKDVFDNAIRAAL 208


>gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
           isoform 1 [Homo sapiens]
          Length = 189

 Score = 98.6 bits (244), Expect = 3e-21
 Identities = 69/198 (34%), Positives = 101/198 (51%), Gaps = 25/198 (12%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           M   K VVVG G VGK+ L I    N F  EY PT+ D+Y  Q  +DG T  L++ DTAG
Sbjct: 1   MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEV--CHHCPDVPILLVGTKKD 118
           QEEY  +R         F+  F+I +  S+E++ H++  ++       DVP++LVG K D
Sbjct: 61  QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDI-HQYREQIKRVKDSDDVPMVLVGNKCD 119

Query: 119 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAV-- 176
           L A+              +  +Q Q LA+  + + Y+E SA  + GV++ F   VR +  
Sbjct: 120 LAAR-------------TVESRQAQDLARS-YGIPYIETSAKTRQGVEDAFYTLVREIRQ 165

Query: 177 -----LNPTPIKRGRSCI 189
                LNP P + G  C+
Sbjct: 166 HKLRKLNP-PDESGPGCM 182


>gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
           isoform 1 [Homo sapiens]
          Length = 189

 Score = 98.6 bits (244), Expect = 3e-21
 Identities = 69/198 (34%), Positives = 101/198 (51%), Gaps = 25/198 (12%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           M   K VVVG G VGK+ L I    N F  EY PT+ D+Y  Q  +DG T  L++ DTAG
Sbjct: 1   MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEV--CHHCPDVPILLVGTKKD 118
           QEEY  +R         F+  F+I +  S+E++ H++  ++       DVP++LVG K D
Sbjct: 61  QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDI-HQYREQIKRVKDSDDVPMVLVGNKCD 119

Query: 119 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAV-- 176
           L A+              +  +Q Q LA+  + + Y+E SA  + GV++ F   VR +  
Sbjct: 120 LAAR-------------TVESRQAQDLARS-YGIPYIETSAKTRQGVEDAFYTLVREIRQ 165

Query: 177 -----LNPTPIKRGRSCI 189
                LNP P + G  C+
Sbjct: 166 HKLRKLNP-PDESGPGCM 182


>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
          Length = 184

 Score = 93.2 bits (230), Expect = 1e-19
 Identities = 60/196 (30%), Positives = 100/196 (51%), Gaps = 17/196 (8%)

Query: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 60
           M+  K VV+G G VGK+ L + +    F ++Y PT+ D+Y  Q  VD +   L + DTAG
Sbjct: 1   MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 60

Query: 61  QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEV-CHHCPDVPILLVGTKKDL 119
            E++  +R L       F + +SI +  ++ +++      +      DVP++LVG K DL
Sbjct: 61  TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 120

Query: 120 RAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNP 179
                       + +  +  +QGQ LA+Q     +LE SA  +  V E+F + VR +   
Sbjct: 121 ------------EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRK 168

Query: 180 TPIK----RGRSCILL 191
           TP++    + +SC+LL
Sbjct: 169 TPVEKKKPKKKSCLLL 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,611,399
Number of Sequences: 37866
Number of extensions: 316231
Number of successful extensions: 1191
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 174
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 837
Number of HSP's gapped (non-prelim): 204
length of query: 191
length of database: 18,247,518
effective HSP length: 96
effective length of query: 95
effective length of database: 14,612,382
effective search space: 1388176290
effective search space used: 1388176290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.