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Search of human proteins with 46094079
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46094079 hepatitis delta antigen-interacting protein A [Homo
sapiens]
(202 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46094079 hepatitis delta antigen-interacting protein A [Homo ... 407 e-114
gi|223671856 coiled-coil domain containing 85C [Homo sapiens] 180 6e-46
gi|122937261 coiled-coil domain containing 85A [Homo sapiens] 165 3e-41
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 43 2e-04
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 41 8e-04
gi|147902746 MEX3A protein [Homo sapiens] 40 0.001
gi|148746195 trichohyalin [Homo sapiens] 39 0.003
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 39 0.004
gi|7019371 TCF3 (E2A) fusion partner [Homo sapiens] 38 0.005
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 38 0.005
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 37 0.009
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 37 0.015
gi|219803769 trichoplein [Homo sapiens] 37 0.015
gi|14150056 trichoplein [Homo sapiens] 37 0.015
gi|21687188 hypothetical protein LOC146325 [Homo sapiens] 37 0.015
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 37 0.015
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] 37 0.015
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 36 0.019
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 36 0.019
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 36 0.019
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 36 0.019
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 36 0.025
gi|21735548 centrosomal protein 2 [Homo sapiens] 36 0.025
gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] 36 0.025
gi|239750672 PREDICTED: hypothetical protein [Homo sapiens] 36 0.025
gi|239744982 PREDICTED: hypothetical protein [Homo sapiens] 36 0.025
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 36 0.025
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 36 0.025
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 36 0.025
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 36 0.025
>gi|46094079 hepatitis delta antigen-interacting protein A [Homo
sapiens]
Length = 202
Score = 407 bits (1046), Expect = e-114
Identities = 202/202 (100%), Positives = 202/202 (100%)
Query: 1 MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI 60
MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI
Sbjct: 1 MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI 60
Query: 61 RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKL 120
RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKL
Sbjct: 61 RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKL 120
Query: 121 AELEGRQEELLRENLALKELCLALGEEWGPRGGPSGAGGSGAGPAPELALPPCGPRDLGD 180
AELEGRQEELLRENLALKELCLALGEEWGPRGGPSGAGGSGAGPAPELALPPCGPRDLGD
Sbjct: 121 AELEGRQEELLRENLALKELCLALGEEWGPRGGPSGAGGSGAGPAPELALPPCGPRDLGD 180
Query: 181 GSSSTGSVGSPDQLPLACSPDD 202
GSSSTGSVGSPDQLPLACSPDD
Sbjct: 181 GSSSTGSVGSPDQLPLACSPDD 202
>gi|223671856 coiled-coil domain containing 85C [Homo sapiens]
Length = 419
Score = 180 bits (457), Expect = 6e-46
Identities = 102/204 (50%), Positives = 128/204 (62%), Gaps = 19/204 (9%)
Query: 8 LEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLN 67
L ++ DEE+ KEEL RRLRR E ++ +++ G LM++VNR+LQ HL EIR LK +N
Sbjct: 15 LSQVPDEELLRWSKEELARRLRRAEGEKVGLMLEHGGLMRDVNRRLQQHLLEIRGLKDVN 74
Query: 68 RRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQ 127
+RLQ +N+ELR+LCCFLD +RQ+GR+ AR+WQ FG A+ AV ++ QKL ELE RQ
Sbjct: 75 QRLQDDNQELRELCCFLDDDRQKGRKLAREWQRFGRHAAGAVWHEVARSQQKLRELEARQ 134
Query: 128 EELLRENLALKELCLALGEE---WGPRGGPSGAGGSGAGPAPELAL-------------- 170
E LLRENL LKEL L L EE G SG GG G G ++
Sbjct: 135 EALLRENLELKELVLLLDEERAALAATGAASGGGGGGGGAGSRSSIDSQASLSGPLSGGA 194
Query: 171 PPCGPRDLGDGS--SSTGSVGSPD 192
P G RD+GDGS SS GS GSPD
Sbjct: 195 PGAGARDVGDGSSTSSAGSGGSPD 218
>gi|122937261 coiled-coil domain containing 85A [Homo sapiens]
Length = 553
Score = 165 bits (417), Expect = 3e-41
Identities = 90/193 (46%), Positives = 129/193 (66%), Gaps = 13/193 (6%)
Query: 8 LEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLN 67
L +++DEE+ KEEL+R LRR EA +++A++ L++EVNR+LQ HLGEIR LK +N
Sbjct: 36 LSKVSDEELLQWSKEELIRSLRRAEAEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDIN 95
Query: 68 RRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQ 127
++LQ +N+ELRDLCCFLD +RQ+G+R +R+WQ G + + +++ QKL +LE +Q
Sbjct: 96 QKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQ 155
Query: 128 EELLRENLALKELCLALGEEWGPRGGPSGAGGSGAGPAPELAL----PPCGP--RDLGDG 181
EE+++EN+ LKELC+ L EE G +G GS + +L P RD+GDG
Sbjct: 156 EEVVKENMELKELCVLLDEEKG-----AGCAGSRCSIDSQASLCQLTASTAPYVRDVGDG 210
Query: 182 S--SSTGSVGSPD 192
S SSTGS SPD
Sbjct: 211 SSTSSTGSTDSPD 223
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 42.7 bits (99), Expect = 2e-04
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 7/93 (7%)
Query: 98 WQLFGTQASRAVREDLGGCWQKLAELEGRQEELLRENLALKELCLALGEEWGPRGGPSGA 157
W+L RA L ++ + E +E N A + ALG +WGP GG SG
Sbjct: 116 WRLAELAQQRAAHTFLIHGSRRFSYSEAERES----NRAARAFLRALGWDWGPDGGDSGE 171
Query: 158 GGSGAGPAPELALPPCGPRDLGDGSSSTGSVGS 190
G +G G E A P G G G+ G G+
Sbjct: 172 GSAGEG---ERAAPGAGDAAAGSGAEFAGGDGA 201
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 40.8 bits (94), Expect = 8e-04
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 19/173 (10%)
Query: 9 EELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI----RELK 64
E L D + G E +RRL R+EA L+ +R L +E L+ G + EL+
Sbjct: 279 ELLLDSQAEVQGLEAEIRRL-RQEAQALSGQAKRAELYREEAEALRERAGRLPRLQEELR 337
Query: 65 QLNRRLQA------ENRELRDLCCFLDS-----ERQRGRRAARQWQLFGTQASR-AVRED 112
+ RLQA + E R L L++ E Q R +L TQ +R
Sbjct: 338 RCRERLQAAEAYKSQLEEERVLSGVLEASKALLEEQLEAARERCARLHETQRENLLLRTR 397
Query: 113 LGGCWQKLAELEGRQEELLRENLALKELCLALGEEWGPRGGPSGAGGSGAGPA 165
LG +L L + ++L EN+ L EL L E P G P A +GA P+
Sbjct: 398 LGEAHAELDSLRHQVDQLAEENVEL-ELELQRSLE-PPPGSPGEAPLAGAAPS 448
Score = 36.6 bits (83), Expect = 0.015
Identities = 41/135 (30%), Positives = 59/135 (43%), Gaps = 28/135 (20%)
Query: 22 EELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLC 81
E+L + EA +A L +R RLMQ+ +RQ R L++ RRLQ+E+ + L
Sbjct: 1121 EQLQAQRASVEAQEVALLAERERLMQDGHRQ--------RGLEEELRRLQSEHDRAQMLL 1172
Query: 82 CFLDSER--QRGRRAARQWQLFGTQASRAVRE-------------DLGGC-----WQKLA 121
L ER +G R + +L + RA E DL C + L
Sbjct: 1173 AELSRERGELQGERGELRGRLARLELERAQLEMQSQQLRESNQQLDLSACRLTTQCELLT 1232
Query: 122 ELEGRQEELLRENLA 136
+L QEE R+ LA
Sbjct: 1233 QLRSAQEEENRQLLA 1247
Score = 33.1 bits (74), Expect = 0.16
Identities = 44/146 (30%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Query: 8 LEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLN 67
LE L +E AA +E R ++ AL Q L + +L+G L R+LK
Sbjct: 1050 LEVLEEEVRAARQSQEETRGQQQALLRDHKALAQ---LQRRQEAELEGLLVRHRDLKANM 1106
Query: 68 RRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKL-AELEGR 126
R L+ +REL+ E+ + +RA+ + Q A R G + L EL
Sbjct: 1107 RALELAHRELQG-----RHEQLQAQRASVEAQEVALLAERERLMQDGHRQRGLEEELRRL 1161
Query: 127 QEELLRENLALKELCLALGEEWGPRG 152
Q E R + L EL GE G RG
Sbjct: 1162 QSEHDRAQMLLAELSRERGELQGERG 1187
Score = 32.7 bits (73), Expect = 0.22
Identities = 56/220 (25%), Positives = 73/220 (33%), Gaps = 36/220 (16%)
Query: 9 EELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIR------- 61
E L + G EE +RRL+ E L + R E LQG GE+R
Sbjct: 1142 ERLMQDGHRQRGLEEELRRLQSEHDRAQMLLAELSRERGE----LQGERGELRGRLARLE 1197
Query: 62 -----------ELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVR 110
+L++ N++L L C L R RQ SR R
Sbjct: 1198 LERAQLEMQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENR 1257
Query: 111 EDLGGCWQKLAELEGRQEELL-------RENLALKELCLALGEEWGPRGGPSGAGGSGAG 163
E L + L Q E L RE L E + P P GS
Sbjct: 1258 ELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKIMDQYRVLEPVPLPRTKKGSWLA 1317
Query: 164 PAPELAL-------PPCGPRDLGDGSSSTGSVGSPDQLPL 196
+ + PP G R DG+ ST S+G P + L
Sbjct: 1318 DKVKRLMRPRREGGPPGGLRLGADGAGSTESLGGPPETEL 1357
Score = 28.9 bits (63), Expect = 3.1
Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 21/125 (16%)
Query: 25 VRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFL 84
+RRLR+E L ++ L+ + ++QG EIR L+Q + L + +
Sbjct: 267 LRRLRQE-------LEEKAELLLDSQAEVQGLEAEIRRLRQEAQALSGQAKRAELYREEA 319
Query: 85 DSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQEELLRENL--ALKELCL 142
++ R+R R R ++E+L C ++L E + +L E + + E
Sbjct: 320 EALRERAGRLPR------------LQEELRRCRERLQAAEAYKSQLEEERVLSGVLEASK 367
Query: 143 ALGEE 147
AL EE
Sbjct: 368 ALLEE 372
Score = 28.1 bits (61), Expect = 5.3
Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 15/108 (13%)
Query: 37 AALVQRGRLMQEVNRQLQGHLGEIR----ELKQLNRRLQAENRELRDLCCFLDSERQRGR 92
A LV +Q + L+G LG ++ EL ++R Q + L+ L+ + Q
Sbjct: 988 AMLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSVLEIQGQELH 1047
Query: 93 RAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQEELLRENLALKEL 140
R + E++ Q E G+Q+ LLR++ AL +L
Sbjct: 1048 RKLE-----------VLEEEVRAARQSQEETRGQQQALLRDHKALAQL 1084
>gi|147902746 MEX3A protein [Homo sapiens]
Length = 520
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 115 GCWQKLAELEGRQEELLRENLALKELCL-ALGEEWGPRGGPSGAGGSGAGPAPELALPPC 173
GC+ A+ G E+ LAL +LCL LGE P G G GG G PA A P
Sbjct: 20 GCFGGSAKDRGLLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQP 79
Query: 174 GP 175
P
Sbjct: 80 AP 81
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 38.9 bits (89), Expect = 0.003
Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 9/130 (6%)
Query: 9 EELTDEEMAALGKEELVRRLRREEAAR-----LAALVQRGRLMQEVNRQLQGHLGEIREL 63
E+L EE ++EL R+ R+EE + L R QE RQ + E EL
Sbjct: 1061 EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR----EEEEL 1116
Query: 64 KQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAEL 123
+Q +L E RE R R+ + QL + + R++L +++ EL
Sbjct: 1117 QQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEEL 1176
Query: 124 EGRQEELLRE 133
+ +E+LLRE
Sbjct: 1177 QQEEEQLLRE 1186
Score = 38.1 bits (87), Expect = 0.005
Identities = 40/135 (29%), Positives = 61/135 (45%), Gaps = 19/135 (14%)
Query: 9 EELTDEEMAALGKEELVRRLRREEAAR-----LAALVQRGRLMQEVNRQLQGHLGEIREL 63
E+L EE ++E ++ R EE + L + R QE RQ + + EL
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR----KKDEL 1026
Query: 64 KQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQ-----LFGTQASRAVREDLGGCWQ 118
+Q +L E RE R L ER+R R + Q L G + R++L ++
Sbjct: 1027 QQEEEQLLREEREKRRL-----QERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 119 KLAELEGRQEELLRE 133
K EL+ +E+LLRE
Sbjct: 1082 KEEELQQEEEQLLRE 1096
Score = 34.7 bits (78), Expect = 0.057
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 24/138 (17%)
Query: 9 EELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNR 68
EE K L +LR+E+ +L+QE +LQ E R ++ R
Sbjct: 880 EERKRRRHTLYAKPALQEQLRKEQ-----------QLLQEEEEELQREEREKRRRQEQER 928
Query: 69 RLQAENRELRDLCCFLDSERQRGRRAAR-------------QWQLFGTQASRAVREDLGG 115
+ + E + ++ L ER++ RR R + QL G + + R++
Sbjct: 929 QYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
Query: 116 CWQKLAELEGRQEELLRE 133
+++ EL+ +E+LLRE
Sbjct: 989 KYREEEELQQEEEQLLRE 1006
Score = 33.1 bits (74), Expect = 0.16
Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 21/132 (15%)
Query: 9 EELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNR 68
EE +E L +EE +R R+E + ++ + +Q+ QL G E R ++ +
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQY----RKDKKLQQKEEQLLGEEPEKRRRQEREK 988
Query: 69 RLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQE 128
+ + E ++ L ER++ RR ++W+ R+ ++K EL+ +E
Sbjct: 989 KYREEEELQQEEEQLLREEREKRRR--QEWE----------RQ-----YRKKDELQQEEE 1031
Query: 129 ELLRENLALKEL 140
+LLRE + L
Sbjct: 1032 QLLREEREKRRL 1043
Score = 31.2 bits (69), Expect = 0.63
Identities = 44/142 (30%), Positives = 61/142 (42%), Gaps = 22/142 (15%)
Query: 11 LTDEEMAALGKEELVRRLRREEAARLAALVQRG------RLMQEVNRQLQGHLG--EIRE 62
L EE L +E +RL+RE+ R L++R RL +E +L+ L E+
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609
Query: 63 LKQLNRR---LQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVR--------E 111
L+Q RR L+ E E L SE Q R RQ QL Q R + E
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEER---RQQQLRREQQERREQRLKREEEEE 666
Query: 112 DLGGCWQKLAELEGRQEELLRE 133
L ++ E E R++EL E
Sbjct: 667 RLEQRLKREHEEERREQELAEE 688
Score = 30.0 bits (66), Expect = 1.4
Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 19/129 (14%)
Query: 13 DEEMAALGKEELVRRLRREEAA--RLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRL 70
+E++ L ++EL R + EE RL Q R +E R+ Q E R +Q R
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ----EERREQQERREQ 330
Query: 71 QAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQEEL 130
Q E RE + +R + R+ QL Q + L ++ E E R+++L
Sbjct: 331 QEERRE---------QQLRREQEERREQQLRREQEEERREQQL----RREQEEERREQQL 377
Query: 131 LRENLALKE 139
RE +E
Sbjct: 378 RREQQLRRE 386
Score = 30.0 bits (66), Expect = 1.4
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 25/142 (17%)
Query: 9 EELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLM-----QEVNRQ--LQGHLGEIR 61
EE + + +E L +RL+REE RL +R + + +E RQ L+ E R
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 62 ELKQLNR--------RLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDL 113
+QL R RL+ E E R L+ +R R+ Q + RE +
Sbjct: 643 RQQQLRREQQERREQRLKREEEEER-----LEQRLKREHEEERREQELAEEEQEQARERI 697
Query: 114 GG-----CWQKLAELEGRQEEL 130
WQ +E + RQ ++
Sbjct: 698 KSRIPKWQWQLESEADARQSKV 719
Score = 29.6 bits (65), Expect = 1.8
Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 10/140 (7%)
Query: 1 MEAEAGGLEELTDEEMAALGKEE--LVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLG 58
++ E L +L +E+ +EE +RLRRE+ R +R R QE R+ Q
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER-REQQEERREQQERRE 329
Query: 59 EIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQ 118
+ E ++ R + E R + L R+ R+ QL Q + L Q
Sbjct: 330 QQEERREQQLRREQEERREQQL-------RREQEEERREQQLRREQEEERREQQLRREQQ 382
Query: 119 KLAELEGRQEELLRENLALK 138
E + R+E+ LR L+
Sbjct: 383 LRREQQLRREQQLRREQQLR 402
Score = 29.6 bits (65), Expect = 1.8
Identities = 38/138 (27%), Positives = 62/138 (44%), Gaps = 23/138 (16%)
Query: 8 LEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLN 67
L E + ++ A +++ +R EE + QR R +E ++LQ + E +QL
Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEK----EQRRRQRREREKELQF----LEEEEQLQ 841
Query: 68 RRLQAENRELRDLCCFLDSERQRGRRAAR----QWQLFGTQASR--------AVREDLGG 115
RR +A+ + + D ER+R + R +WQL + R A++E L
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901
Query: 116 CWQKLAELEGRQEELLRE 133
Q L E +EEL RE
Sbjct: 902 EQQLLQE---EEEELQRE 916
Score = 28.5 bits (62), Expect = 4.1
Identities = 25/112 (22%), Positives = 51/112 (45%)
Query: 21 KEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDL 80
+E +RL+RE+ R L + + + + L +E ++ R L+ E E R+
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ 499
Query: 81 CCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQEELLR 132
+ + +R + R+ +L + +++ L Q E E R+E+LL+
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Score = 28.1 bits (61), Expect = 5.3
Identities = 36/139 (25%), Positives = 61/139 (43%), Gaps = 25/139 (17%)
Query: 13 DEEMAALGKEELVRRLRREEAARL----------AALVQRGRLMQEVNRQLQGHLGEI-- 60
+EE +E ++LRRE+ R L QR R Q++ R+ + ++
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Query: 61 ----RELKQLNR--RLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLG 114
+ L+Q R RL+ E E RD + ER++ R Q + R RE++
Sbjct: 552 REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL---EQRLKREEV- 607
Query: 115 GCWQKLAELEGRQEELLRE 133
++L + E R++ L RE
Sbjct: 608 ---ERLEQEERREQRLKRE 623
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 38.5 bits (88), Expect = 0.004
Identities = 45/142 (31%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 19 LGKEELVRRLRREEAARLAALVQRGRL---MQEVNRQLQGHLGEIRELKQLNRRLQAEN- 74
L E+ ++L E AR A + G L +QEV R E++EL++ + L +EN
Sbjct: 1238 LANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENT 1297
Query: 75 ---RELRDLCCFL------DSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEG 125
REL +L L + E +R RQ L G + +R++L +KL E EG
Sbjct: 1298 RLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEG 1357
Query: 126 RQEELLRENLALKELCLALGEE 147
E RE L L A G E
Sbjct: 1358 --EFRTRERRLLGSLEEARGTE 1377
Score = 34.7 bits (78), Expect = 0.057
Identities = 36/129 (27%), Positives = 54/129 (41%), Gaps = 14/129 (10%)
Query: 15 EMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAEN 74
E A +E+L R R +EAA +R +L ++ RE ++L RL+AE
Sbjct: 986 EQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQ----------REQEELLARLEAEK 1035
Query: 75 RELRDLCCFLDSERQRGRRAA--RQWQLFGTQASR--AVREDLGGCWQKLAELEGRQEEL 130
EL + L ER G A + Q + S A+ E L G LA + E
Sbjct: 1036 EELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQ 1095
Query: 131 LRENLALKE 139
R+ + +E
Sbjct: 1096 KRDAQSRQE 1104
Score = 32.7 bits (73), Expect = 0.22
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 21 KEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDL 80
+EE VRR RE A L + R +Q +L+ +I ++K +L+ + R L+++
Sbjct: 1584 QEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEV 1643
Query: 81 CCFLDSERQR 90
LD+ R
Sbjct: 1644 ---LDASESR 1650
Score = 32.0 bits (71), Expect = 0.37
Identities = 41/163 (25%), Positives = 60/163 (36%), Gaps = 36/163 (22%)
Query: 9 EELTDEEMAALGKEELVRRLRREE------------------------AARLAALVQRGR 44
E+L G+E+ + + RRE A +L A + GR
Sbjct: 834 EQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGR 893
Query: 45 LMQE-------VNRQLQGHLGEI-RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAAR 96
+ E L+G L E+ R+L QL R E E L E G A
Sbjct: 894 TLSEEATRLRLEKEALEGSLFEVQRQLAQLEAR--REQLEAEGQALLLAKETLTGELAGL 951
Query: 97 QWQLFGTQASRAVREDLGGCWQKLAELEGRQEELLRENLALKE 139
+ Q+ TQ ++ ++L QKL + E + LRE A E
Sbjct: 952 RQQIIATQEKASLDKELMA--QKLVQAEREAQASLREQRAAHE 992
Score = 31.6 bits (70), Expect = 0.48
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 20/136 (14%)
Query: 24 LVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCF 83
L ++L E+ R A Q RL + + +Q H RE+++L + +RE +L
Sbjct: 552 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHS 611
Query: 84 L--------------------DSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAEL 123
L E +R R + Q Q VR +L ++L +L
Sbjct: 612 LQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQL 671
Query: 124 EGRQEELLRENLALKE 139
EG++ L +E + ++E
Sbjct: 672 EGKRSVLAKELVEVRE 687
Score = 27.3 bits (59), Expect = 9.0
Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 3/126 (2%)
Query: 15 EMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAEN 74
++A EEL + + +AA+ QR RL +E +Q REL++ +R+L+
Sbjct: 613 QVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLE 672
Query: 75 RELRDLCCFLDSERQRGRRAARQWQLFGTQASRA-VREDLGGCWQKLAELEGRQEELLRE 133
+ L L R+ RA Q + QA +A V E L ELE +L E
Sbjct: 673 GKRSVLAKELVEVREALSRATLQRDML--QAEKAEVAEALTKAEAGRVELELSMTKLRAE 730
Query: 134 NLALKE 139
+L++
Sbjct: 731 EASLQD 736
>gi|7019371 TCF3 (E2A) fusion partner [Homo sapiens]
Length = 253
Score = 38.1 bits (87), Expect = 0.005
Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 6/71 (8%)
Query: 7 GLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQL 66
GL E +EE AA G+ R L R + AL +R R +++VN ++ L + +++++
Sbjct: 56 GLRERDEEEEAARGRRRRQRELNRR---KYQALGRRCREIEQVNERV---LNRLHQVQRI 109
Query: 67 NRRLQAENREL 77
RRLQ E R L
Sbjct: 110 TRRLQQERRFL 120
Score = 29.6 bits (65), Expect = 1.8
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 8 LEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGE-IRELKQL 66
LE + LG L R EEAAR R R +E+NR+ LG RE++Q+
Sbjct: 41 LETEVEFVSGGLGGSGLRERDEEEEAAR-----GRRRRQRELNRRKYQALGRRCREIEQV 95
Query: 67 NRRLQAENRELRDLCCFLDSERQ 89
N R+ +++ + L ER+
Sbjct: 96 NERVLNRLHQVQRITRRLQQERR 118
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 38.1 bits (87), Expect = 0.005
Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)
Query: 1 MEAEAGGLEE---LTDEEMAALGKE-ELVRRLRREEAARLAALVQRGRLMQEVNRQLQGH 56
+E E LE+ L ++E L ++ EL + + A+L+A+ + R + + + +
Sbjct: 823 LEQEVAQLEKDKKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESRALDKELARCRDA 882
Query: 57 LGEIRELKQLNRRLQAE----NRELRDLCCFLDSERQRGR-------RAARQWQLFGTQA 105
G+++EL++ NR L + R L L L E+ + + + +++ + G
Sbjct: 883 AGKLKELEKDNRDLTKQVTVHARTLTTLREDLVLEKLKSQQLSSELDKLSQELEKVGLNR 942
Query: 106 SRAVREDLGGCWQKLAELEGRQEELLRENLALKELCLALGE 146
++ED G K LEGR E L+ LA+KE + L E
Sbjct: 943 ELLLQEDDSGSDTKYKILEGRNESALKTTLAMKEEKIVLLE 983
Score = 33.5 bits (75), Expect = 0.13
Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 22/126 (17%)
Query: 25 VRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFL 84
+RR+R+E + LV + ++ + E++++KQ N +L A+ R R L
Sbjct: 263 LRRVRQELEDKTEQLV-------DTRHEVDQLVLELQKVKQENIQLAADARSARAYRDEL 315
Query: 85 DSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELE---GRQEELLRENLALKELC 141
DS R++ R R + +L C +KL +++ R EEL +N+ L E
Sbjct: 316 DSLREKANRVER------------LELELTRCKEKLHDVDFYKARMEELREDNIILIETK 363
Query: 142 LALGEE 147
L E+
Sbjct: 364 AMLEEQ 369
Score = 28.5 bits (62), Expect = 4.1
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 11/88 (12%)
Query: 4 EAGGLEELTDEEMAALGKEE--LVRRLRREEAA--RLAALVQRGRLMQEVNRQLQGHLGE 59
E G E + E+ L +E L R++ E A ++ AL + +Q NR L+ L
Sbjct: 625 EKGERAEKLERELQRLQEENGRLARKVTSLETATEKVEALEHESQGLQLENRTLRKSLDT 684
Query: 60 IRE-------LKQLNRRLQAENRELRDL 80
++ L++ N++L AEN ELR L
Sbjct: 685 LQNVSLQLEGLERDNKQLDAENLELRRL 712
Score = 27.7 bits (60), Expect = 6.9
Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 9 EELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQ---GHLGEIRELKQ 65
E+LT A L E + L ++A AL+++ ++ ++R L+ LGE R
Sbjct: 1158 EQLTAAYEALLQDHEHLGTLHERQSAEYEALIRQHSCLKTLHRNLELEHKELGE-RHGDM 1216
Query: 66 LNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEG 125
L R+ + E RE L +ER+ ++ R L + R +R +L +L+G
Sbjct: 1217 LKRKAELEEREK-----VLTTEREALQQEQRTNALAMGENQR-LRGELDRVNFLHHQLKG 1270
Query: 126 RQEELLRENLALK 138
EEL LK
Sbjct: 1271 EYEELHAHTKELK 1283
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 37.4 bits (85), Expect = 0.009
Identities = 22/49 (44%), Positives = 23/49 (46%), Gaps = 5/49 (10%)
Query: 150 PRGGPSGAGGSGAGPAPELALPPCGPR---DLGDGSSSTGSVGSPDQLP 195
P GG GAGG+G GP P P G R G G GS G P Q P
Sbjct: 16 PAGGGGGAGGAGGGPPP--GPPGAGDRGGGGPGGGGPGGGSAGGPSQPP 62
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 36.6 bits (83), Expect = 0.015
Identities = 51/172 (29%), Positives = 76/172 (44%), Gaps = 22/172 (12%)
Query: 9 EELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNR 68
E L ++E +EE +R + E L + RL++EV + L+ E R+ +Q
Sbjct: 304 ERLREQEERLCEQEERLRE-QEERLCEQEKLPGQERLLEEVEKLLE---QERRQEEQ--E 357
Query: 69 RLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVRE-----DLG--GCWQKLA 121
RL R L ++ L+ ER R ++ R WQ Q +RE +LG +++ A
Sbjct: 358 RLLERERLLEEVEELLEQERLR-QQDERLWQQETLQELERLRELERMLELGWEALYEQRA 416
Query: 122 ELEGRQEELLRENLA-------LKELCLALGEEWGPRGGPSGAGGSGAGPAP 166
E EEL EN + +KEL + G E PRG S A AP
Sbjct: 417 EPRSGFEELNNENKSTLQLEQQVKELKKSGGAE-EPRGSESAAAARPVAGAP 467
Score = 28.5 bits (62), Expect = 4.1
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 14/92 (15%)
Query: 46 MQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQA 105
++ V RQLQ + + L LNRR + RE + R++ R Q + Q
Sbjct: 173 LESVGRQLQAEVENNQMLSLLNRRQEERLREQEERL------REQEERLREQEERLCEQE 226
Query: 106 SRAVREDLGGCWQKLAELEGR---QEELLREN 134
R ++ ++L E E R QEE LRE+
Sbjct: 227 ERLREQE-----ERLREQEERLCEQEERLREH 253
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 36.6 bits (83), Expect = 0.015
Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 13/142 (9%)
Query: 8 LEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLN 67
LE + E+ L +EE + EA R RLM EV L G +I+E + N
Sbjct: 338 LERAREAELQMLLREEAKEMWEKREAEWARERSARDRLMSEV---LTGRQQQIQEKIEQN 394
Query: 68 RRLQAENRELRD-LCCFLDSERQRGRR---------AARQWQLFGTQASRAVREDLGGCW 117
RR Q E+ + R+ L L+ R+ RR +AR+ +L A R ++
Sbjct: 395 RRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVAERRLQAWEADQQ 454
Query: 118 QKLAELEGRQEELLRENLALKE 139
++ E E R+ E L + L +E
Sbjct: 455 EEEEEEEARRVEQLSDALLQQE 476
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 36.6 bits (83), Expect = 0.015
Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 13/142 (9%)
Query: 8 LEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLN 67
LE + E+ L +EE + EA R RLM EV L G +I+E + N
Sbjct: 338 LERAREAELQMLLREEAKEMWEKREAEWARERSARDRLMSEV---LTGRQQQIQEKIEQN 394
Query: 68 RRLQAENRELRD-LCCFLDSERQRGRR---------AARQWQLFGTQASRAVREDLGGCW 117
RR Q E+ + R+ L L+ R+ RR +AR+ +L A R ++
Sbjct: 395 RRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVAERRLQAWEADQQ 454
Query: 118 QKLAELEGRQEELLRENLALKE 139
++ E E R+ E L + L +E
Sbjct: 455 EEEEEEEARRVEQLSDALLQQE 476
>gi|21687188 hypothetical protein LOC146325 [Homo sapiens]
Length = 571
Score = 36.6 bits (83), Expect = 0.015
Identities = 37/113 (32%), Positives = 50/113 (44%), Gaps = 16/113 (14%)
Query: 102 GTQASRAVREDLGGCWQKLAELEGRQEELLRENLALKELCL---------ALGEEWG-PR 151
G A R +RE LG +L + E+ +R A +L + ALGE WG P
Sbjct: 429 GGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPE 488
Query: 152 GGPSGAGGSGAGPAPELALPPCGPRDLGDGSSSTGSVGS--PDQLPLACSPDD 202
GP GG+ P P L P P+ ++ + S P LPLA +PDD
Sbjct: 489 LGPVLTGGT---PEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLA-APDD 537
Score = 28.5 bits (62), Expect = 4.1
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Query: 147 EWGPRGGPSGAGGSGAGPAPELALPPCGPRDLGDG--SSSTGSVGSP 191
E P P GA +GA PAP+L + G G S + GS G P
Sbjct: 95 ESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPP 141
>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
Length = 1044
Score = 36.6 bits (83), Expect = 0.015
Identities = 42/138 (30%), Positives = 63/138 (45%), Gaps = 7/138 (5%)
Query: 14 EEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIR-ELKQLNRRLQA 72
+E + E ++RLR + A L+ L Q R +QE +L+G LGE E +L ++
Sbjct: 876 KEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQ 935
Query: 73 ENRELRDLCCF---LDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQEE 129
+ R L D L SER + R Q F + + A E+ +LA L+ RQ+
Sbjct: 936 KERALEDAQAVNEQLSSERSNLAQVIR--QEFEDRLA-ASEEETRQAKAELATLQARQQL 992
Query: 130 LLRENLALKELCLALGEE 147
L E + LA EE
Sbjct: 993 ELEEVHRRVKTALARKEE 1010
>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
Length = 1080
Score = 36.6 bits (83), Expect = 0.015
Identities = 42/138 (30%), Positives = 63/138 (45%), Gaps = 7/138 (5%)
Query: 14 EEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIR-ELKQLNRRLQA 72
+E + E ++RLR + A L+ L Q R +QE +L+G LGE E +L ++
Sbjct: 912 KEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQ 971
Query: 73 ENRELRDLCCF---LDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQEE 129
+ R L D L SER + R Q F + + A E+ +LA L+ RQ+
Sbjct: 972 KERALEDAQAVNEQLSSERSNLAQVIR--QEFEDRLA-ASEEETRQAKAELATLQARQQL 1028
Query: 130 LLRENLALKELCLALGEE 147
L E + LA EE
Sbjct: 1029 ELEEVHRRVKTALARKEE 1046
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 36.2 bits (82), Expect = 0.019
Identities = 47/151 (31%), Positives = 63/151 (41%), Gaps = 31/151 (20%)
Query: 1 MEAEAGGLEELTDEEMAA---LGKEELV--------RRLRREEAARLAALVQRGRLMQEV 49
MEAEA GL E +EE AA G+E RR + EEA L A + R
Sbjct: 1366 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1425
Query: 50 NRQLQGHLGE----IRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFG--- 102
L L E + L++ RRLQ +EL D L+ +RQ ++ + F
Sbjct: 1426 AEALTQRLAEKTETVDRLERGRRRLQ---QELDDATMDLEQQRQLVSTLEKKQRKFDQLL 1482
Query: 103 ----TQASRAVREDLGGCWQKLAELEGRQEE 129
RAV E ++ AE EGR+ E
Sbjct: 1483 AEEKAAVLRAVEE------RERAEAEGRERE 1507
Score = 30.8 bits (68), Expect = 0.82
Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 8/128 (6%)
Query: 6 GGLEELTDEEMAA-LGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELK 64
G LEEL + +A GKEE V++LR+ + A + + R ++E + + RE +
Sbjct: 1649 GELEELKAQMASAGQGKEEAVKQLRKMQ----AQMKELWREVEETRTSREEIFSQNRESE 1704
Query: 65 QLNRRLQAENRELRDLCCFLDSER---QRGRRAARQWQLFGTQASRAVREDLGGCWQKLA 121
+ + L+AE L++ D R Q+ R G + A+ E+ +L
Sbjct: 1705 KRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLG 1764
Query: 122 ELEGRQEE 129
+LE EE
Sbjct: 1765 QLEEELEE 1772
Score = 30.0 bits (66), Expect = 1.4
Identities = 33/116 (28%), Positives = 49/116 (42%), Gaps = 20/116 (17%)
Query: 1 MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVN----RQLQGH 56
+EA G LE+ D A ++ +R R +E L ++ + E RQ G
Sbjct: 1173 LEALRGELEDTLDSTNA----QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1228
Query: 57 -LGEIRELKQLNRR-----------LQAENRELRDLCCFLDSERQRGRRAARQWQL 100
LGE+ E + RR L+AE ELR L + RQ G + R+ +L
Sbjct: 1229 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1284
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 36.2 bits (82), Expect = 0.019
Identities = 47/151 (31%), Positives = 63/151 (41%), Gaps = 31/151 (20%)
Query: 1 MEAEAGGLEELTDEEMAA---LGKEELV--------RRLRREEAARLAALVQRGRLMQEV 49
MEAEA GL E +EE AA G+E RR + EEA L A + R
Sbjct: 1358 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1417
Query: 50 NRQLQGHLGE----IRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFG--- 102
L L E + L++ RRLQ +EL D L+ +RQ ++ + F
Sbjct: 1418 AEALTQRLAEKTETVDRLERGRRRLQ---QELDDATMDLEQQRQLVSTLEKKQRKFDQLL 1474
Query: 103 ----TQASRAVREDLGGCWQKLAELEGRQEE 129
RAV E ++ AE EGR+ E
Sbjct: 1475 AEEKAAVLRAVEE------RERAEAEGRERE 1499
Score = 30.8 bits (68), Expect = 0.82
Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 8/128 (6%)
Query: 6 GGLEELTDEEMAA-LGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELK 64
G LEEL + +A GKEE V++LR+ + A + + R ++E + + RE +
Sbjct: 1641 GELEELKAQMASAGQGKEEAVKQLRKMQ----AQMKELWREVEETRTSREEIFSQNRESE 1696
Query: 65 QLNRRLQAENRELRDLCCFLDSER---QRGRRAARQWQLFGTQASRAVREDLGGCWQKLA 121
+ + L+AE L++ D R Q+ R G + A+ E+ +L
Sbjct: 1697 KRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLG 1756
Query: 122 ELEGRQEE 129
+LE EE
Sbjct: 1757 QLEEELEE 1764
Score = 30.0 bits (66), Expect = 1.4
Identities = 33/116 (28%), Positives = 49/116 (42%), Gaps = 20/116 (17%)
Query: 1 MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVN----RQLQGH 56
+EA G LE+ D A ++ +R R +E L ++ + E RQ G
Sbjct: 1165 LEALRGELEDTLDSTNA----QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1220
Query: 57 -LGEIRELKQLNRR-----------LQAENRELRDLCCFLDSERQRGRRAARQWQL 100
LGE+ E + RR L+AE ELR L + RQ G + R+ +L
Sbjct: 1221 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1276
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 36.2 bits (82), Expect = 0.019
Identities = 47/151 (31%), Positives = 63/151 (41%), Gaps = 31/151 (20%)
Query: 1 MEAEAGGLEELTDEEMAA---LGKEELV--------RRLRREEAARLAALVQRGRLMQEV 49
MEAEA GL E +EE AA G+E RR + EEA L A + R
Sbjct: 1399 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1458
Query: 50 NRQLQGHLGE----IRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFG--- 102
L L E + L++ RRLQ +EL D L+ +RQ ++ + F
Sbjct: 1459 AEALTQRLAEKTETVDRLERGRRRLQ---QELDDATMDLEQQRQLVSTLEKKQRKFDQLL 1515
Query: 103 ----TQASRAVREDLGGCWQKLAELEGRQEE 129
RAV E ++ AE EGR+ E
Sbjct: 1516 AEEKAAVLRAVEE------RERAEAEGRERE 1540
Score = 30.8 bits (68), Expect = 0.82
Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 8/128 (6%)
Query: 6 GGLEELTDEEMAA-LGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELK 64
G LEEL + +A GKEE V++LR+ + A + + R ++E + + RE +
Sbjct: 1682 GELEELKAQMASAGQGKEEAVKQLRKMQ----AQMKELWREVEETRTSREEIFSQNRESE 1737
Query: 65 QLNRRLQAENRELRDLCCFLDSER---QRGRRAARQWQLFGTQASRAVREDLGGCWQKLA 121
+ + L+AE L++ D R Q+ R G + A+ E+ +L
Sbjct: 1738 KRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLG 1797
Query: 122 ELEGRQEE 129
+LE EE
Sbjct: 1798 QLEEELEE 1805
Score = 30.0 bits (66), Expect = 1.4
Identities = 33/116 (28%), Positives = 49/116 (42%), Gaps = 20/116 (17%)
Query: 1 MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVN----RQLQGH 56
+EA G LE+ D A ++ +R R +E L ++ + E RQ G
Sbjct: 1206 LEALRGELEDTLDSTNA----QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1261
Query: 57 -LGEIRELKQLNRR-----------LQAENRELRDLCCFLDSERQRGRRAARQWQL 100
LGE+ E + RR L+AE ELR L + RQ G + R+ +L
Sbjct: 1262 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1317
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 36.2 bits (82), Expect = 0.019
Identities = 48/192 (25%), Positives = 80/192 (41%), Gaps = 31/192 (16%)
Query: 10 ELTDEEMAALGKEELVRRLRRE-------------EAARLAALVQRGR-----LMQEVNR 51
EL++ + KE LV++L+ E E A+ A + R L ++++
Sbjct: 1215 ELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDE 1274
Query: 52 QLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQAS---RA 108
QL +E++ L + + RE++ L LD Q+GR+ Q
Sbjct: 1275 QLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEM 1334
Query: 109 VREDLGGCWQ-------KLAELEGRQEELLRENLALKELCLALGEEWGPRGGPSGAGGSG 161
+EDL + K++EL+ + LL++N LK L L G R P G S
Sbjct: 1335 AQEDLSMTQKDKFMLQAKVSELKNNMKTLLQQNQQLK-LDLRRGAA-KTRKEPKGE-ASS 1391
Query: 162 AGPAPELALPPC 173
+ PA + +P C
Sbjct: 1392 SNPATPIKIPDC 1403
Score = 28.5 bits (62), Expect = 4.1
Identities = 39/148 (26%), Positives = 62/148 (41%), Gaps = 26/148 (17%)
Query: 1 MEAEAGGLEELTDEEMAALGK--EEL------VRRLRREEAARLAAL-------VQRGRL 45
++ A LEE T+E L K EEL V L++E AA + +Q+ +
Sbjct: 792 LDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVM 851
Query: 46 MQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQA 105
++ R I ELK +RL +E +ELR + E++ +
Sbjct: 852 VEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAE----------AEL 901
Query: 106 SRAVREDLGGCWQKLAELEGRQEELLRE 133
SR RE + Q +A+LEG + +E
Sbjct: 902 SRLHRE-VAQVRQHMADLEGHLQSAQKE 928
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 35.8 bits (81), Expect = 0.025
Identities = 32/147 (21%), Positives = 69/147 (46%), Gaps = 11/147 (7%)
Query: 8 LEELTDEEMAALGKEELVRRLRREEAARLAALVQ----RGRLMQE---VNRQLQGHLGEI 60
L +++ +E + KEE + ++R ++ A L + + +LM E + QLQ
Sbjct: 837 LLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELC 896
Query: 61 RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKL 120
E ++L RL A+ +EL ++C L++ + + Q + +++++ ++L
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQ----AEKKKMQQNIQELEEQL 952
Query: 121 AELEGRQEELLRENLALKELCLALGEE 147
E E +++L E + + L EE
Sbjct: 953 EEEESARQKLQLEKVTTEAKLKKLEEE 979
Score = 31.6 bits (70), Expect = 0.48
Identities = 33/155 (21%), Positives = 63/155 (40%), Gaps = 32/155 (20%)
Query: 1 MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGE- 59
+E LE+ +E L EEL L+ E A+L V + + R LQG +
Sbjct: 1523 LEKSKRALEQQVEEMKTQL--EELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQS 1580
Query: 60 -------IRELKQLNRRLQAENR--------------ELRDLCCFLDSERQRGRRAARQW 98
+R+++++ L+ E + +L+DL +DS + A +Q
Sbjct: 1581 EEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQ- 1639
Query: 99 QLFGTQASRAVREDLGGCWQKLAELEGRQEELLRE 133
R ++ + C ++L + +EE+L +
Sbjct: 1640 -------LRKLQAQMKDCMRELDDTRASREEILAQ 1667
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 35.8 bits (81), Expect = 0.025
Identities = 36/120 (30%), Positives = 53/120 (44%), Gaps = 15/120 (12%)
Query: 2 EAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQ-------LQ 54
+AE G E D KEE+ ++L + AA Q +L QE RQ +Q
Sbjct: 670 KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQ 729
Query: 55 GHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQW---QLFGTQASRAVRE 111
+RE L RLQA R+ +DL +E+ +G +A++ LF Q +V E
Sbjct: 730 EKEALVREKAALEVRLQAVERDRQDL-----AEQLQGLSSAKELLESSLFEAQQQNSVIE 784
Score = 30.0 bits (66), Expect = 1.4
Identities = 30/93 (32%), Positives = 38/93 (40%), Gaps = 12/93 (12%)
Query: 58 GEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQAS----------- 106
GE+ L + LQ ELR L+ E R RR + QL G A
Sbjct: 456 GEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELH 515
Query: 107 RAVREDLGGCWQKLAELEGRQEELLRENLALKE 139
AVRE + L LE +Q E L E + L+E
Sbjct: 516 LAVRE-RERLQEMLMGLEAKQSESLSELITLRE 547
>gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]
Length = 625
Score = 35.8 bits (81), Expect = 0.025
Identities = 40/125 (32%), Positives = 54/125 (43%), Gaps = 16/125 (12%)
Query: 11 LTDEEMAALGKEELVR-----RLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQ 65
L ++ AA G+ EL R R REE + AL Q R + +G G RE ++
Sbjct: 370 LLEQRAAAHGQWELQRVHAKQRREREEREKQRALEQGRRAWAAQVEERRGRRG--REERE 427
Query: 66 LNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEG 125
RR Q + SE +R A RQ L +A RA RED Q+ L+
Sbjct: 428 AARRRQRQYER---------SEERRRELAERQGLLRRERAERAAREDRLRKLQQEQNLKQ 478
Query: 126 RQEEL 130
R+E L
Sbjct: 479 REEGL 483
>gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]
Length = 627
Score = 35.8 bits (81), Expect = 0.025
Identities = 40/125 (32%), Positives = 54/125 (43%), Gaps = 16/125 (12%)
Query: 11 LTDEEMAALGKEELVR-----RLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQ 65
L ++ AA G+ EL R R REE + AL Q R + +G G RE ++
Sbjct: 372 LLEQRAAAHGQWELQRVHAKQRREREEREKQRALEQGRRAWAAQVEERRGRRG--REERE 429
Query: 66 LNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEG 125
RR Q + SE +R A RQ L +A RA RED Q+ L+
Sbjct: 430 AARRRQRQYER---------SEERRRELAERQGLLRRERAERAAREDRLRKLQQEQNLKQ 480
Query: 126 RQEEL 130
R+E L
Sbjct: 481 REEGL 485
>gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]
Length = 627
Score = 35.8 bits (81), Expect = 0.025
Identities = 40/125 (32%), Positives = 54/125 (43%), Gaps = 16/125 (12%)
Query: 11 LTDEEMAALGKEELVR-----RLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQ 65
L ++ AA G+ EL R R REE + AL Q R + +G G RE ++
Sbjct: 372 LLEQRAAAHGQWELQRVHAKQRREREEREKQRALEQGRRAWAAQVEERRGRRG--REERE 429
Query: 66 LNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEG 125
RR Q + SE +R A RQ L +A RA RED Q+ L+
Sbjct: 430 AARRRQRQYER---------SEERRRELAERQGLLRRERAERAAREDRLRKLQQEQNLKQ 480
Query: 126 RQEEL 130
R+E L
Sbjct: 481 REEGL 485
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 35.8 bits (81), Expect = 0.025
Identities = 43/151 (28%), Positives = 65/151 (43%), Gaps = 16/151 (10%)
Query: 1 MEAEAGGLEELTDE--EMAALGKE-ELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHL 57
+EAEAG EL +E + AL +E + R+L E+AAR A +R V + +
Sbjct: 1789 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAER------VLAEKLAAI 1842
Query: 58 GEIRELKQ----LNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDL 113
GE LK + +AEN LR L + E + RR Q + +
Sbjct: 1843 GEATRLKTEAEIALKEKEAENERLRRLA---EDEAFQRRRLEEQAAQHKADIEERLAQLR 1899
Query: 114 GGCWQKLAELEGRQEELLRENLALKELCLAL 144
+L +G E+ LR+ ++E LAL
Sbjct: 1900 KASDSELERQKGLVEDTLRQRRQVEEEILAL 1930
Score = 31.6 bits (70), Expect = 0.48
Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 15/133 (11%)
Query: 1 MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI 60
++AE ++ + A KEE R RR A A+ QR QE+ +Q Q G
Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1705
Query: 61 RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKL 120
++ RL AE +R L +E ++G +Q QL + +R RE QK
Sbjct: 1706 QQ------RLAAEQELIR-----LRAETEQGE---QQRQLLEEELARLQRE-AAAATQKR 1750
Query: 121 AELEGRQEELLRE 133
ELE ++ E
Sbjct: 1751 QELEAELAKVRAE 1763
Score = 31.2 bits (69), Expect = 0.63
Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 11/133 (8%)
Query: 2 EAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI- 60
EA+ + L DE G +E+ RL++ R + + + ++ + Q L +
Sbjct: 1140 EAQQPTFDALRDE---LRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTD 1196
Query: 61 ---RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCW 117
REL+QL R+L R R+ L + Q RR Q Q S+AVRE L
Sbjct: 1197 VRQRELEQLGRQL----RYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQ 1252
Query: 118 QKLAELEGRQEEL 130
L E+E E++
Sbjct: 1253 ALLEEIERHGEKV 1265
Score = 30.4 bits (67), Expect = 1.1
Identities = 42/147 (28%), Positives = 54/147 (36%), Gaps = 28/147 (19%)
Query: 2 EAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQ---------------RGRLM 46
E + GG E A + E +R +EEA RL VQ R +
Sbjct: 1465 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524
Query: 47 QEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQAS 106
E R+ Q L + EL RLQAE E R RQ ARQ Q+ A
Sbjct: 1525 AEAAREKQRALQALEEL-----RLQAEEAERR--------LRQAEVERARQVQVALETAQ 1571
Query: 107 RAVREDLGGCWQKLAELEGRQEELLRE 133
R+ +L AE + E L+E
Sbjct: 1572 RSAEAELQSKRASFAEKTAQLERSLQE 1598
Score = 29.6 bits (65), Expect = 1.8
Identities = 39/141 (27%), Positives = 58/141 (41%), Gaps = 6/141 (4%)
Query: 2 EAEAGGLE-ELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI 60
E E G + +L +EE+A L +E +R+E L A + + R EV + E
Sbjct: 1721 ETEQGEQQRQLLEEELARLQREAAAATQKRQE---LEAELAKVRAEMEVLLASKARAEEE 1777
Query: 61 REL--KQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQ 118
++ +RL+AE R+L R A RQ QL A+R E +
Sbjct: 1778 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1837
Query: 119 KLAELEGRQEELLRENLALKE 139
KLA + +ALKE
Sbjct: 1838 KLAAIGEATRLKTEAEIALKE 1858
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 35.8 bits (81), Expect = 0.025
Identities = 43/151 (28%), Positives = 65/151 (43%), Gaps = 16/151 (10%)
Query: 1 MEAEAGGLEELTDE--EMAALGKE-ELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHL 57
+EAEAG EL +E + AL +E + R+L E+AAR A +R V + +
Sbjct: 1793 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAER------VLAEKLAAI 1846
Query: 58 GEIRELKQ----LNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDL 113
GE LK + +AEN LR L + E + RR Q + +
Sbjct: 1847 GEATRLKTEAEIALKEKEAENERLRRLA---EDEAFQRRRLEEQAAQHKADIEERLAQLR 1903
Query: 114 GGCWQKLAELEGRQEELLRENLALKELCLAL 144
+L +G E+ LR+ ++E LAL
Sbjct: 1904 KASDSELERQKGLVEDTLRQRRQVEEEILAL 1934
Score = 31.6 bits (70), Expect = 0.48
Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 15/133 (11%)
Query: 1 MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI 60
++AE ++ + A KEE R RR A A+ QR QE+ +Q Q G
Sbjct: 1650 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1709
Query: 61 RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKL 120
++ RL AE +R L +E ++G +Q QL + +R RE QK
Sbjct: 1710 QQ------RLAAEQELIR-----LRAETEQGE---QQRQLLEEELARLQRE-AAAATQKR 1754
Query: 121 AELEGRQEELLRE 133
ELE ++ E
Sbjct: 1755 QELEAELAKVRAE 1767
Score = 31.2 bits (69), Expect = 0.63
Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 11/133 (8%)
Query: 2 EAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI- 60
EA+ + L DE G +E+ RL++ R + + + ++ + Q L +
Sbjct: 1144 EAQQPTFDALRDE---LRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTD 1200
Query: 61 ---RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCW 117
REL+QL R+L R R+ L + Q RR Q Q S+AVRE L
Sbjct: 1201 VRQRELEQLGRQL----RYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQ 1256
Query: 118 QKLAELEGRQEEL 130
L E+E E++
Sbjct: 1257 ALLEEIERHGEKV 1269
Score = 30.4 bits (67), Expect = 1.1
Identities = 42/147 (28%), Positives = 54/147 (36%), Gaps = 28/147 (19%)
Query: 2 EAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQ---------------RGRLM 46
E + GG E A + E +R +EEA RL VQ R +
Sbjct: 1469 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1528
Query: 47 QEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQAS 106
E R+ Q L + EL RLQAE E R RQ ARQ Q+ A
Sbjct: 1529 AEAAREKQRALQALEEL-----RLQAEEAERR--------LRQAEVERARQVQVALETAQ 1575
Query: 107 RAVREDLGGCWQKLAELEGRQEELLRE 133
R+ +L AE + E L+E
Sbjct: 1576 RSAEAELQSKRASFAEKTAQLERSLQE 1602
Score = 29.6 bits (65), Expect = 1.8
Identities = 39/141 (27%), Positives = 58/141 (41%), Gaps = 6/141 (4%)
Query: 2 EAEAGGLE-ELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI 60
E E G + +L +EE+A L +E +R+E L A + + R EV + E
Sbjct: 1725 ETEQGEQQRQLLEEELARLQREAAAATQKRQE---LEAELAKVRAEMEVLLASKARAEEE 1781
Query: 61 REL--KQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQ 118
++ +RL+AE R+L R A RQ QL A+R E +
Sbjct: 1782 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1841
Query: 119 KLAELEGRQEELLRENLALKE 139
KLA + +ALKE
Sbjct: 1842 KLAAIGEATRLKTEAEIALKE 1862
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 35.8 bits (81), Expect = 0.025
Identities = 43/151 (28%), Positives = 65/151 (43%), Gaps = 16/151 (10%)
Query: 1 MEAEAGGLEELTDE--EMAALGKE-ELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHL 57
+EAEAG EL +E + AL +E + R+L E+AAR A +R V + +
Sbjct: 1789 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAER------VLAEKLAAI 1842
Query: 58 GEIRELKQ----LNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDL 113
GE LK + +AEN LR L + E + RR Q + +
Sbjct: 1843 GEATRLKTEAEIALKEKEAENERLRRLA---EDEAFQRRRLEEQAAQHKADIEERLAQLR 1899
Query: 114 GGCWQKLAELEGRQEELLRENLALKELCLAL 144
+L +G E+ LR+ ++E LAL
Sbjct: 1900 KASDSELERQKGLVEDTLRQRRQVEEEILAL 1930
Score = 31.6 bits (70), Expect = 0.48
Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 15/133 (11%)
Query: 1 MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI 60
++AE ++ + A KEE R RR A A+ QR QE+ +Q Q G
Sbjct: 1646 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1705
Query: 61 RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKL 120
++ RL AE +R L +E ++G +Q QL + +R RE QK
Sbjct: 1706 QQ------RLAAEQELIR-----LRAETEQGE---QQRQLLEEELARLQRE-AAAATQKR 1750
Query: 121 AELEGRQEELLRE 133
ELE ++ E
Sbjct: 1751 QELEAELAKVRAE 1763
Score = 31.2 bits (69), Expect = 0.63
Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 11/133 (8%)
Query: 2 EAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI- 60
EA+ + L DE G +E+ RL++ R + + + ++ + Q L +
Sbjct: 1140 EAQQPTFDALRDE---LRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTD 1196
Query: 61 ---RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCW 117
REL+QL R+L R R+ L + Q RR Q Q S+AVRE L
Sbjct: 1197 VRQRELEQLGRQL----RYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQ 1252
Query: 118 QKLAELEGRQEEL 130
L E+E E++
Sbjct: 1253 ALLEEIERHGEKV 1265
Score = 30.4 bits (67), Expect = 1.1
Identities = 42/147 (28%), Positives = 54/147 (36%), Gaps = 28/147 (19%)
Query: 2 EAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQ---------------RGRLM 46
E + GG E A + E +R +EEA RL VQ R +
Sbjct: 1465 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524
Query: 47 QEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQAS 106
E R+ Q L + EL RLQAE E R RQ ARQ Q+ A
Sbjct: 1525 AEAAREKQRALQALEEL-----RLQAEEAERR--------LRQAEVERARQVQVALETAQ 1571
Query: 107 RAVREDLGGCWQKLAELEGRQEELLRE 133
R+ +L AE + E L+E
Sbjct: 1572 RSAEAELQSKRASFAEKTAQLERSLQE 1598
Score = 29.6 bits (65), Expect = 1.8
Identities = 39/141 (27%), Positives = 58/141 (41%), Gaps = 6/141 (4%)
Query: 2 EAEAGGLE-ELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI 60
E E G + +L +EE+A L +E +R+E L A + + R EV + E
Sbjct: 1721 ETEQGEQQRQLLEEELARLQREAAAATQKRQE---LEAELAKVRAEMEVLLASKARAEEE 1777
Query: 61 REL--KQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQ 118
++ +RL+AE R+L R A RQ QL A+R E +
Sbjct: 1778 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1837
Query: 119 KLAELEGRQEELLRENLALKE 139
KLA + +ALKE
Sbjct: 1838 KLAAIGEATRLKTEAEIALKE 1858
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 35.8 bits (81), Expect = 0.025
Identities = 43/151 (28%), Positives = 65/151 (43%), Gaps = 16/151 (10%)
Query: 1 MEAEAGGLEELTDE--EMAALGKE-ELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHL 57
+EAEAG EL +E + AL +E + R+L E+AAR A +R V + +
Sbjct: 1757 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAER------VLAEKLAAI 1810
Query: 58 GEIRELKQ----LNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDL 113
GE LK + +AEN LR L + E + RR Q + +
Sbjct: 1811 GEATRLKTEAEIALKEKEAENERLRRLA---EDEAFQRRRLEEQAAQHKADIEERLAQLR 1867
Query: 114 GGCWQKLAELEGRQEELLRENLALKELCLAL 144
+L +G E+ LR+ ++E LAL
Sbjct: 1868 KASDSELERQKGLVEDTLRQRRQVEEEILAL 1898
Score = 31.6 bits (70), Expect = 0.48
Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 15/133 (11%)
Query: 1 MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI 60
++AE ++ + A KEE R RR A A+ QR QE+ +Q Q G
Sbjct: 1614 LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1673
Query: 61 RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKL 120
++ RL AE +R L +E ++G +Q QL + +R RE QK
Sbjct: 1674 QQ------RLAAEQELIR-----LRAETEQGE---QQRQLLEEELARLQRE-AAAATQKR 1718
Query: 121 AELEGRQEELLRE 133
ELE ++ E
Sbjct: 1719 QELEAELAKVRAE 1731
Score = 31.2 bits (69), Expect = 0.63
Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 11/133 (8%)
Query: 2 EAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI- 60
EA+ + L DE G +E+ RL++ R + + + ++ + Q L +
Sbjct: 1108 EAQQPTFDALRDE---LRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTD 1164
Query: 61 ---RELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCW 117
REL+QL R+L R R+ L + Q RR Q Q S+AVRE L
Sbjct: 1165 VRQRELEQLGRQL----RYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQ 1220
Query: 118 QKLAELEGRQEEL 130
L E+E E++
Sbjct: 1221 ALLEEIERHGEKV 1233
Score = 30.4 bits (67), Expect = 1.1
Identities = 42/147 (28%), Positives = 54/147 (36%), Gaps = 28/147 (19%)
Query: 2 EAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQ---------------RGRLM 46
E + GG E A + E +R +EEA RL VQ R +
Sbjct: 1433 ERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1492
Query: 47 QEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQAS 106
E R+ Q L + EL RLQAE E R RQ ARQ Q+ A
Sbjct: 1493 AEAAREKQRALQALEEL-----RLQAEEAERR--------LRQAEVERARQVQVALETAQ 1539
Query: 107 RAVREDLGGCWQKLAELEGRQEELLRE 133
R+ +L AE + E L+E
Sbjct: 1540 RSAEAELQSKRASFAEKTAQLERSLQE 1566
Score = 29.6 bits (65), Expect = 1.8
Identities = 39/141 (27%), Positives = 58/141 (41%), Gaps = 6/141 (4%)
Query: 2 EAEAGGLE-ELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEI 60
E E G + +L +EE+A L +E +R+E L A + + R EV + E
Sbjct: 1689 ETEQGEQQRQLLEEELARLQREAAAATQKRQE---LEAELAKVRAEMEVLLASKARAEEE 1745
Query: 61 REL--KQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQ 118
++ +RL+AE R+L R A RQ QL A+R E +
Sbjct: 1746 SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1805
Query: 119 KLAELEGRQEELLRENLALKE 139
KLA + +ALKE
Sbjct: 1806 KLAAIGEATRLKTEAEIALKE 1826
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.135 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,853,188
Number of Sequences: 37866
Number of extensions: 499469
Number of successful extensions: 4916
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 326
Number of HSP's that attempted gapping in prelim test: 4127
Number of HSP's gapped (non-prelim): 1062
length of query: 202
length of database: 18,247,518
effective HSP length: 97
effective length of query: 105
effective length of database: 14,574,516
effective search space: 1530324180
effective search space used: 1530324180
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.