BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|46049092 nebulin-related anchoring protein isoform C [Homo sapiens] (1695 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|46049092 nebulin-related anchoring protein isoform C [Homo sa... 3423 0.0 gi|46049105 nebulin-related anchoring protein isoform S [Homo sa... 3405 0.0 gi|115527120 nebulin [Homo sapiens] 1176 0.0 gi|169217576 PREDICTED: similar to nebulin [Homo sapiens] 330 7e-90 gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 194 6e-49 gi|239752495 PREDICTED: similar to nebulin [Homo sapiens] 159 3e-38 gi|47087157 nebulette non-muscle isoform [Homo sapiens] 125 5e-28 gi|5453710 LIM and SH3 protein 1 [Homo sapiens] 105 3e-22 gi|116517305 cysteine-rich protein 3 [Homo sapiens] 54 1e-06 gi|4503049 cysteine-rich protein 2 [Homo sapiens] 54 1e-06 gi|189083753 cysteine and glycine-rich protein 3 [Homo sapiens] 51 1e-05 gi|4502893 cysteine and glycine-rich protein 3 [Homo sapiens] 51 1e-05 gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens] 50 1e-05 gi|4503101 cysteine and glycine-rich protein 2 [Homo sapiens] 50 2e-05 gi|4758086 cysteine and glycine-rich protein 1 isoform 1 [Homo s... 47 2e-04 gi|165905591 LIM domain and actin binding 1 isoform c [Homo sapi... 46 3e-04 gi|165905589 LIM domain and actin binding 1 isoform a [Homo sapi... 46 3e-04 gi|7705373 LIM domain and actin binding 1 isoform b [Homo sapiens] 46 3e-04 gi|119372315 xin actin-binding repeat containing 2 isoform 2 [Ho... 45 6e-04 gi|7662330 actin binding LIM protein family, member 3 [Homo sapi... 44 0.001 gi|221316627 cysteine and glycine-rich protein 1 isoform 2 [Homo... 44 0.002 gi|13386490 LIM domain containing 2 [Homo sapiens] 42 0.004 gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 42 0.005 gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 42 0.005 gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 42 0.005 gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 42 0.005 gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 42 0.005 gi|194272207 actin binding LIM protein family, member 2 isoform ... 42 0.005 gi|153792514 actin binding LIM protein family, member 2 isoform ... 42 0.005 gi|194272204 actin binding LIM protein family, member 2 isoform ... 42 0.005 >gi|46049092 nebulin-related anchoring protein isoform C [Homo sapiens] Length = 1695 Score = 3423 bits (8875), Expect = 0.0 Identities = 1695/1695 (100%), Positives = 1695/1695 (100%) Query: 1 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK Sbjct: 1 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60 Query: 61 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE Sbjct: 61 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120 Query: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR 180 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR Sbjct: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR 180 Query: 181 AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS 240 AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS Sbjct: 181 AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS 240 Query: 241 FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE 300 FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE Sbjct: 241 FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE 300 Query: 301 EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ 360 EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ Sbjct: 301 EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ 360 Query: 361 AQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDY 420 AQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDY Sbjct: 361 AQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDY 420 Query: 421 NYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRAD 480 NYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRAD Sbjct: 421 NYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRAD 480 Query: 481 YEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASG 540 YEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASG Sbjct: 481 YEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASG 540 Query: 541 ELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMV 600 ELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMV Sbjct: 541 ELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMV 600 Query: 601 NIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGW 660 NIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGW Sbjct: 601 NIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGW 660 Query: 661 LTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGN 720 LTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGN Sbjct: 661 LTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGN 720 Query: 721 EQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRD 780 EQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRD Sbjct: 721 EQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRD 780 Query: 781 LASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSL 840 LASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSL Sbjct: 781 LASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSL 840 Query: 841 DMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKG 900 DMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKG Sbjct: 841 DMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKG 900 Query: 901 MGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYR 960 MGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYR Sbjct: 901 MGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYR 960 Query: 961 EQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKA 1020 EQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKA Sbjct: 961 EQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKA 1020 Query: 1021 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH 1080 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH Sbjct: 1021 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH 1080 Query: 1081 LPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNF 1140 LPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNF Sbjct: 1081 LPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNF 1140 Query: 1141 MRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNER 1200 MRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNER Sbjct: 1141 MRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNER 1200 Query: 1201 LYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQA 1260 LYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQA Sbjct: 1201 LYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQA 1260 Query: 1261 ARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQA 1320 ARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQA Sbjct: 1261 ARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQA 1320 Query: 1321 QFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSD 1380 QFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSD Sbjct: 1321 QFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSD 1380 Query: 1381 LIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHC 1440 LIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHC Sbjct: 1381 LIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHC 1440 Query: 1441 NERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIP 1500 NERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIP Sbjct: 1441 NERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIP 1500 Query: 1501 FQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAK 1560 FQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAK Sbjct: 1501 FQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAK 1560 Query: 1561 SRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKY 1620 SRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKY Sbjct: 1561 SRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKY 1620 Query: 1621 KSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPD 1680 KSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPD Sbjct: 1621 KSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPD 1680 Query: 1681 ATEILHVKKKKALLL 1695 ATEILHVKKKKALLL Sbjct: 1681 ATEILHVKKKKALLL 1695 >gi|46049105 nebulin-related anchoring protein isoform S [Homo sapiens] Length = 1730 Score = 3405 bits (8829), Expect = 0.0 Identities = 1695/1730 (97%), Positives = 1695/1730 (97%), Gaps = 35/1730 (2%) Query: 1 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK Sbjct: 1 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60 Query: 61 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE Sbjct: 61 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120 Query: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR 180 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR Sbjct: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR 180 Query: 181 AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS 240 AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS Sbjct: 181 AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS 240 Query: 241 FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE 300 FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE Sbjct: 241 FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE 300 Query: 301 EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ 360 EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ Sbjct: 301 EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ 360 Query: 361 AQSVNKLVSE-----------------------------------NKYKENYQNHMRGRY 385 AQSVNKLVSE NKYKENYQNHMRGRY Sbjct: 361 AQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRY 420 Query: 386 EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR 445 EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR Sbjct: 421 EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR 480 Query: 446 QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK 505 QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK Sbjct: 481 QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK 540 Query: 506 LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADS 565 LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADS Sbjct: 541 LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADS 600 Query: 566 RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYT 625 RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYT Sbjct: 601 RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYT 660 Query: 626 VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQ 685 VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQ Sbjct: 661 VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQ 720 Query: 686 RVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAAN 745 RVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAAN Sbjct: 721 RVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAAN 780 Query: 746 LSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQ 805 LSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQ Sbjct: 781 LSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQ 840 Query: 806 GDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEH 865 GDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEH Sbjct: 841 GDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEH 900 Query: 866 HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKK 925 HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKK Sbjct: 901 HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKK 960 Query: 926 YRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLN 985 YRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLN Sbjct: 961 YRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLN 1020 Query: 986 AMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSR 1045 AMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSR Sbjct: 1021 AMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSR 1080 Query: 1046 SLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKH 1105 SLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKH Sbjct: 1081 SLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKH 1140 Query: 1106 PLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELIS 1165 PLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELIS Sbjct: 1141 PLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELIS 1200 Query: 1166 ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA 1225 ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA Sbjct: 1201 ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA 1260 Query: 1226 KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI 1285 KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI Sbjct: 1261 KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI 1320 Query: 1286 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD 1345 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD Sbjct: 1321 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD 1380 Query: 1346 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE 1405 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE Sbjct: 1381 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE 1440 Query: 1406 LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF 1465 LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF Sbjct: 1441 LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF 1500 Query: 1466 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1525 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG Sbjct: 1501 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1560 Query: 1526 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1585 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS Sbjct: 1561 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1620 Query: 1586 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR 1645 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR Sbjct: 1621 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR 1680 Query: 1646 AAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILHVKKKKALLL 1695 AAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILHVKKKKALLL Sbjct: 1681 AAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILHVKKKKALLL 1730 >gi|115527120 nebulin [Homo sapiens] Length = 6669 Score = 1176 bits (3042), Expect = 0.0 Identities = 615/1520 (40%), Positives = 969/1520 (63%), Gaps = 38/1520 (2%) Query: 155 EEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELL 214 + Y +YE+ RGKG FP IT Y+ KK +Q YK D+ ++F+ V D+P LL Sbjct: 456 KNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHT-YKVHPDK--TKFTQVTDSPVLL 512 Query: 215 RSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQK---- 270 +++ ++ SD+ Y +E ++ K P TPA+ K SD Y Q ++K Sbjct: 513 QAQVNSKQLSDLNYKAKHESEKFKCHIPPD-TPAFIQHKVNAYNLSDNLYKQDWEKSKAK 571 Query: 271 --EMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGK--GSFPAMITPAYQNAKKAH 326 +++ A P + A+ T+ +D Y ++YE+++GK G P ++ K Sbjct: 572 KFDIKVDAIPLLAAKAN-TKNTSDVM---YKKDYEKNKGKMIGVLSINDDPKMLHSLKVA 627 Query: 327 ELASDIKYRQDFNKMKGAA-HYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRY 385 + SD Y++++ K K + +Y P Q + K SE +YK+ Y + G Y Sbjct: 628 KNQSDRLYKENYEKTKAKSMNYCETPKY------QLDTQLKNFSEARYKDLYVKDVLGHY 681 Query: 386 EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR 445 G D H MKV + S+ +YKA+Y+ D +P T+T Y+ KL KD Y+ Sbjct: 682 VGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKLDQCKDHTYK 741 Query: 446 QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK 505 DK K+++VTD+P ++QA++N +QLS +NY+A +E K +P D PQ ++ + NA Sbjct: 742 VHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRVNAY 801 Query: 506 LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA-- 563 S+ YK+ WEK+K K F++K+DA+ LLAAKA+ + S++ YK++YEK+KGK +G Sbjct: 802 NLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSI 861 Query: 564 --DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKL 621 D ++LHSL+ AK S+ EY+K +E+SKT + P+DM+ + AKK+Q +ASD+DY+ L Sbjct: 862 NDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHIL 921 Query: 622 HEYTVLPEDMKTQWAKKAYGLQSELQYKADL-AWMKGVGWLTEGSLNLEQAKKAGQLVSE 680 H Y+ P+ + AKKAY LQS+++YKAD +WMKG GW+ GSL +E+AK+A +++E Sbjct: 922 HSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAKRASDILNE 981 Query: 681 KNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQAR 740 K YRQ D LKFTS+ D+ +K +Q +S +AYKA E+ +H+Y + D P F+QA+ Sbjct: 982 KKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAK 1041 Query: 741 ANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIG 800 NA N+SE +YK+ ++ KG++LR D++ AAKA R AS+V+YK+DYE+++GK++G Sbjct: 1042 VNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVG 1101 Query: 801 AKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGY 860 + +Q D ++ H + ++K+QS+ EYKK +E TKS+ + DM ++V A+KAQ + ++V Y Sbjct: 1102 FQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVSNVNY 1161 Query: 861 KTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVK-WMKGMGWVATGSLNVEQAKKAGE 919 K + HH+T LP M +E +K +QSDN Y+ D WMKG+GW+ GSL+VE+ KKAG+ Sbjct: 1162 KHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGD 1221 Query: 920 LISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEV 979 ++EKKYRQHPD LKFTSI D+P MVQA+ + Q D LY+ +GE++KH YT + DLP+ Sbjct: 1222 ALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQF 1281 Query: 980 LLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKG 1039 L AK NA NIS+ YK W L G + DA+P AAKAS I SDYKYKEA+EK KG Sbjct: 1282 LQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKG 1341 Query: 1040 QMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLAS 1099 + +G RSL+DD L H + LQSD YKK +E++K +H P DM ++ AK AQ +A+ Sbjct: 1342 KHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVAT 1401 Query: 1100 NQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN-FMRGVACVIPGTLEIEGRK 1158 N +YK PL YT L + + L + +++QS+N+Y+ + N F++G+ + G+LE+E K Sbjct: 1402 NVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVK 1461 Query: 1159 KASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLG 1218 KA + ++E KYRQHP + K+T+V D+ ++ A+ + + ++ YK GE +H+YT+ Sbjct: 1462 KAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPE 1521 Query: 1219 LPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFV 1278 LP+FI+AK NA N+SDA YK W+ A+GY L +A+P AA++S +IASD Y+ + Sbjct: 1522 LPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYE 1581 Query: 1279 KERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQ 1338 K +GK +G S++DDP++ H + ++QS+ +Y++G +S+ ++H P+DMV + AK +Q Sbjct: 1582 KAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQ 1641 Query: 1339 ALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIGWLALRSPQM 1397 +A++ +YR YH +T LP+ L + ++ A +QS+ YKSD MKGIGW+ + S ++ Sbjct: 1642 EVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEV 1701 Query: 1398 ESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLH 1454 E AKKAGE++SE KYR+ P+ +KFT +D+ + K++ ++ ++R+Y + D ++H Sbjct: 1702 EKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIH 1761 Query: 1455 RYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDF 1514 ++PD PD +R+N + +SDK+Y+ WE+ + YD R DAI + ARASR+IASD+ Sbjct: 1762 ---VMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDY 1818 Query: 1515 RYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGL 1574 +YK+A+ + +G IG+RS++DDP++ HF+ V ++QSD EYKK + KS++ FH+ D + Sbjct: 1819 KYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSV 1878 Query: 1575 LQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSD-LNLTRGVGWT 1633 + AK+SQ++A++ +YR + P+ + A+ Q+QSD +YK+D + +G+GW Sbjct: 1879 VAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWL 1938 Query: 1634 PPGSYKVEMARRAAELANAR 1653 P GS + E ++A E+ + + Sbjct: 1939 PLGSLEAEKNKKAMEIISEK 1958 Score = 1087 bits (2812), Expect = 0.0 Identities = 607/1646 (36%), Positives = 961/1646 (58%), Gaps = 92/1646 (5%) Query: 60 KNNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLAN 119 K + S TP ++ + +S + + DG+ K++ H D K+KD E A + Sbjct: 109 KGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVS 168 Query: 120 ERAY---WTGYGEGNAWCPGALPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMIT 175 + Y W + P A PE+V+ V+ ++ YTED+E + +P + Sbjct: 169 KVLYKQNWEDTKDKYLLPPDA---PELVQAVKNTAMFSKKLYTEDWEADKSL-FYPYNDS 224 Query: 176 PAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQ 235 P +R +A + S V YK+G E+ ++F+ + D P++ +K S +Y EDYE + Sbjct: 225 PELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENK 284 Query: 236 -RGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294 +GK S TP +++ A + A+ I TR+ Sbjct: 285 IKGKWS----ETPCFEV------------------------ANARMNADNISTRK----- 311 Query: 295 GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQD 354 Y E++E + + F TP Y+ KKA AS +KY++D+ K KG A Y+ LPA + Sbjct: 312 ---YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASE 368 Query: 355 NLVLKQ---------------------AQSVN--------------KLVSENKYKENYQN 379 N L+Q A+S+N S+ KYK++Y Sbjct: 369 NPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLK 428 Query: 380 HMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPL 439 + G Y G D H MKV + S+ YKA+Y+ D +P T+T Y+ KL Sbjct: 429 DILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQC 488 Query: 440 KDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVK 499 KD Y+ DK K++ VTD+P ++QA++N++QLS +NY+A +E K +P D P ++ Sbjct: 489 KDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQ 548 Query: 500 AKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKA 559 K NA S+ YK+ WEK+K K F++K+DA+ LLAAKA+ + S++ YK++YEK KGK Sbjct: 549 HKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKM 608 Query: 560 MGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR----FHLPMDMVNIRHAKKAQTL 611 +G D ++LHSL++AK S+ YK+ +E++K + P ++ + ++ Sbjct: 609 IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSEAR 668 Query: 612 ASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQA 671 DL + L Y ED K S+ YKA+ KG + + +A Sbjct: 669 YKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEA 728 Query: 672 KKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISK 731 K + Y+ D+ KFT+VTDS + A+ + + S + YKA +E + I Sbjct: 729 IKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPA 788 Query: 732 DEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDY 791 D P F+Q R NA NLS+ +YK WE KAK F++++D++ LAAKA S+V YK+DY Sbjct: 789 DAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDY 848 Query: 792 ERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKA 851 E+S+GK+IGA + D +M HSL+ +K QS+ EY+K +E +K+ LDM+ + A+K+ Sbjct: 849 EKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKS 908 Query: 852 QHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADV-KWMKGMGWVATGSLN 910 Q +A+DV YK H ++ P + V+ AKKAY LQSD +Y+AD WMKG GWV GSL Sbjct: 909 QAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLE 968 Query: 911 VEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHY 970 +E+AK+A ++++EKKYRQHPD LKFTSI+D P VQ++I+ Q D Y+ +GE I H Y Sbjct: 969 MEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKY 1028 Query: 971 TPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKY 1030 DLP+ + AK+NA NISE YK L GY LR DA+P +AAKA+ + SD +Y Sbjct: 1029 NLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQY 1088 Query: 1031 KEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVH 1090 K+ +EK KG+M+G +SL+DD L H + +QSD YKK +E +K++++ P DM +V Sbjct: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVA 1148 Query: 1091 AKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL-NFMRGVACVIP 1149 AKKAQ + SN +YKH L YT L + + L +K ++QS+N+Y+ D N+M+G+ + Sbjct: 1149 AKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPI 1208 Query: 1150 GTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDA 1209 G+L++E KKA + ++E KYRQHP + K+T++ D+P ++ AK + + ++ LYKA GED Sbjct: 1209 GSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDV 1268 Query: 1210 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1269 +H+YTM+ LP+F++AK NA N+SD YK W +L A+G + +A+P AA+AS +IAS Sbjct: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328 Query: 1270 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMV 1329 D+ Y+ + K +GK +G +S++DDP++ H + +LQS+ +Y++ +++ +H P DMV Sbjct: 1329 DYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV 1388 Query: 1330 HLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIG 1388 + AK AQ +A++ +Y+ H +T LP+ + + + + +QS+ YK + +KGIG Sbjct: 1389 SITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIG 1448 Query: 1389 WLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSG 1448 W+ + S ++E KKAG+ ++E KYR+ PD++KFT+V DS +V A+++ ++ Y+ Sbjct: 1449 WIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVE 1508 Query: 1449 DAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASR 1508 + H+YT+ P+ P F +A++NAL++SD Y+ W++T A YD R DAIP A++SR Sbjct: 1509 GEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSR 1568 Query: 1509 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1568 IASD +YKEA+ + +G Q+G+ S+ DDP++ H++NV ++QSD EYKK + S++++H+ Sbjct: 1569 NIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTP 1628 Query: 1569 TDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDL-NLT 1627 D + AK+SQ++A++ +YRQ T P+ L + H++ A Q+QSD YKSD N Sbjct: 1629 LDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWM 1688 Query: 1628 RGVGWTPPGSYKVEMARRAAELANAR 1653 +G+GW P S +VE A++A E+ + + Sbjct: 1689 KGIGWVPIESLEVEKAKKAGEILSEK 1714 Score = 1053 bits (2723), Expect = 0.0 Identities = 583/1535 (37%), Positives = 922/1535 (60%), Gaps = 36/1535 (2%) Query: 136 GALPDPEIVRMVE-ARKSLGEEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYK 194 G++ DP ++ A ++ + Y +YE+ +GK FP IT Y+ KK +Q YK Sbjct: 683 GSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKLDQCKDHT-YK 741 Query: 195 RGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKR 254 D+ ++F+ V D+P LL+++ + SD+ Y +E ++ K PA Q Sbjct: 742 VHPDK--TKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRVN 799 Query: 255 ANELASDVRYHQQYQK------EMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGK 308 A L+ +V Y Q ++K +++ A P + A+ T+ +D Y ++YE+ +GK Sbjct: 800 AYNLSDNV-YKQDWEKSKAKKFDIKVDAIPLLAAKA-NTKNTSDVM---YKKDYEKSKGK 854 Query: 309 --GSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNK 366 G+ P ++ K + SD +YR+D+ K K ++ P D L + QA+ Sbjct: 855 MIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSK---TIYTAPL-DMLQVTQAKKSQA 910 Query: 367 LVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATL 426 + S+ YK H+ Y A K +L S+V YKADY + + Sbjct: 911 IASDVDYK-----HILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFG 965 Query: 427 TPSYQTAMKLVP-LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK 485 + + A + L + YRQ D LK++S+ D P VQ+KIN Q S + Y+A E+ Sbjct: 966 SLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEII 1025 Query: 486 LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 545 Y LP D+PQ ++AK NA SE YK + KG++++ DA+ + AAKA+ + AS+ Sbjct: 1026 HKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASD 1085 Query: 546 IKYKEEYEKTKGKAMG----TADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVN 601 ++YK++YEK KGK +G D +L+H + +AK+ S+ EYKK +E++K++++ P DM N Sbjct: 1086 VQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFN 1145 Query: 602 IRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL-AWMKGVGW 660 + AKKAQ + S+++Y+ LH YT LP+ M + +K +QS+ YK D WMKG+GW Sbjct: 1146 VVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGW 1205 Query: 661 LTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGN 720 + GSL++E+ KKAG ++EK YRQ D LKFTS+ DS M AK++ + S + YKA Sbjct: 1206 IPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKG 1265 Query: 721 EQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRD 780 E H+YT+S D P FLQA+ NA N+S+ YK W + AKG + D++ AAKA R+ Sbjct: 1266 EDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRN 1325 Query: 781 LASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSL 840 +AS+ KYKE YE+S+GK +G + +Q D ++ H + ++KLQS+ EYKK +E+TK+ H Sbjct: 1326 IASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPG 1385 Query: 841 DMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADV-KWMK 899 DMV + A+ AQ +AT+V YK HH+T LP M +E + +QSDN Y+ + ++K Sbjct: 1386 DMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLK 1445 Query: 900 GMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLY 959 G+GW+ GSL VE+ KKAG+ ++E+KYRQHPD +KFTS+ D+ MV A+ + Q D Y Sbjct: 1446 GIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNY 1505 Query: 960 REQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAK 1019 + +GE +KH YT +LP+ + AK+NA+N+S+ YK W K GY LR DA+P AAK Sbjct: 1506 KVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAK 1565 Query: 1020 ASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQF 1079 +S I SD KYKEA+EK KG+ +G SL+DD L H + +QSD YKKG+E SK ++ Sbjct: 1566 SSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKY 1625 Query: 1080 HLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL- 1138 H PLDM ++ AKK+Q +A+N +Y+ YT L + L + ++ A ++QS+NLY+SD Sbjct: 1626 HTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFT 1685 Query: 1139 NFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITN 1198 N+M+G+ V +LE+E KKA E++SE KYRQHP K+T DT K + + Sbjct: 1686 NWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMD 1745 Query: 1199 ERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPF 1258 +RLY + + P+ + ++ N +SD YK W + +GY L +A+ Sbjct: 1746 KRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAI 1805 Query: 1259 QAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSS 1318 +AARAS DIASD+ Y+ + + +GK IG +S+ DDP++ H ++ ++QS+ +Y++G S Sbjct: 1806 KAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKS 1865 Query: 1319 QAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYK 1378 + FH P+DM+ +V AK +Q +A++ +YR H + LP+ + AK +QS+ +YK Sbjct: 1866 KTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYK 1925 Query: 1379 SDLIG-MKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSY 1437 +D MKGIGWL L S + E KKA E+ISE KYR+ PD++K++T++DS ++V A+N+ Sbjct: 1926 ADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNA 1985 Query: 1438 MHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLD 1497 NE +Y+ + ++PD P A+ NA+++SDK+Y+ S E+++ YD R D Sbjct: 1986 KIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKGYDLRPD 2045 Query: 1498 AIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKD 1557 AIP + A+ASR+IASD++YK + + +G +G+RS++DDP++ H + V ++QSD EYKK+ Sbjct: 2046 AIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKN 2105 Query: 1558 FAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSD 1617 + +++ +H+ D + AK +Q ++ +Y+ + + P+ + + + +++QSD Sbjct: 2106 YENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSD 2165 Query: 1618 VKYKSDLN-LTRGVGWTPPGSYKVEMARRAAELAN 1651 +YK D N +G+GW+P GS +VE A++A E A+ Sbjct: 2166 NEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYAS 2200 Score = 1035 bits (2675), Expect = 0.0 Identities = 578/1564 (36%), Positives = 916/1564 (58%), Gaps = 76/1564 (4%) Query: 107 DKEGAPNRQPLANERAYWTGYG---EGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQ 163 D E + N + ++ Y Y +G W P D E V+ +A +L E+ Y Q Sbjct: 1176 DLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVK--KAGDALNEK---KYRQ 1230 Query: 164 PRGKGSFPAMI-TPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQL 222 F +++ +P +AK+ + S + YK ++ +++ D P+ L++K A Sbjct: 1231 HPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYN 1290 Query: 223 QSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGA 282 SDV Y D+ KG+ AK + +ASD +Y + Y+K G +G Sbjct: 1291 ISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSK----GKHVGF 1346 Query: 283 EGILTRECADQY--------GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKY 334 + Y + Y + YE + P + + AK A ++A+++ Y Sbjct: 1347 RSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV-SITAAKMAQDVATNVNY 1405 Query: 335 RQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRT 394 +Q + HY LP D + L+ ++VN++ S+N YK+ Y + ++G Sbjct: 1406 KQPLH------HYTYLP--DAMSLEHTRNVNQIQSDNVYKDEYNSFLKG----------- 1446 Query: 395 LHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 454 + + +GSL KA L + YRQ D +K++ Sbjct: 1447 IGWIPIGSLEVEKVKKAGDA------------------------LNERKYRQHPDTVKFT 1482 Query: 455 SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKE 514 SV D+ +V A+ N +QLS +NY+ + EK K YT+ ++PQ ++AK NA S+ YK Sbjct: 1483 SVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKA 1542 Query: 515 GWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHS 570 W+KT KG++++ DA+ ++AAK+S +AS+ KYKE YEK KGK +G D +L+H Sbjct: 1543 DWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHY 1602 Query: 571 LQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPED 630 + +AK+ S+ EYKKG+E SKT++H P+DMV++ AKK+Q +A++ +YR+ H YT+LP+ Sbjct: 1603 MNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDA 1662 Query: 631 MKTQWAKKAYGLQSELQYKADLA-WMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDE 689 + + ++ A +QS+ YK+D WMKG+GW+ SL +E+AKKAG+++SEK YRQ ++ Sbjct: 1663 LNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEK 1722 Query: 690 LKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEK 749 LKFT D+ + K ++ Y + + D P L +R N +S+K Sbjct: 1723 LKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDK 1782 Query: 750 LYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQ 809 LYK+ WE +K KG++LR D++ AA+A RD+AS+ KYK+ YE+++GK IG + ++ D + Sbjct: 1783 LYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPK 1842 Query: 810 MSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTA 869 + H +Q++K+QS+ EYKKG+E +K+ H +DM+ +V A+K+Q +AT+ Y+ H + Sbjct: 1843 LVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNM 1902 Query: 870 LPTDMKVEWAKKAYGLQSDNQYRAD-VKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQ 928 LP M E AK +QSDNQY+AD +MKG+GW+ GSL E+ KKA E+ISEKKYRQ Sbjct: 1903 LPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQ 1962 Query: 929 HPDALKFTSIKDTPEMVQARISYTQAVDRLYRE--QGENIKHHYTPTADLPEVLLAKLNA 986 HPD LK++++ D+ MV A+ + + LY++ + + K H P D+P+++LAK NA Sbjct: 1963 HPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP--DIPQIILAKANA 2020 Query: 987 MNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRS 1046 +N+S+ YK S + + GY LR DA+P +AAKAS +I SDYKYK +EK KG+M+G RS Sbjct: 2021 INMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRS 2080 Query: 1047 LEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHP 1106 LEDD L HS+ +QSD YKK +E++K +H P DM ++ AK AQ +N +YKH Sbjct: 2081 LEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHL 2140 Query: 1107 LPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN-FMRGVACVIPGTLEIEGRKKASELIS 1165 + +Y L + + + + +++QS+N Y+ D N + +G+ G+LE+E KKA+E S Sbjct: 2141 IHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYAS 2200 Query: 1166 ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA 1225 + KYRQHP +F++ +TD+ +++ AK + N+ LY + + + P+ ++A Sbjct: 2201 DQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQA 2260 Query: 1226 KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI 1285 K N S YK W +GY L ++A+ Q A+AS DIASD+ Y+ + K+ G + Sbjct: 2261 KQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHV 2320 Query: 1286 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD 1345 G +S++DDP++ + ++QSE +Y++ + +F P+DM+ +V AK Q L SD D Sbjct: 2321 GFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVD 2380 Query: 1346 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE 1405 Y+ H++T LP+ + AKK + LQSE YKSDL ++GIGW L S + E K+A E Sbjct: 2381 YKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASE 2440 Query: 1406 LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF 1465 +ISE KYR+ PD KFT++ D+ D+V AK + + ++R+YR + + ++PD PD Sbjct: 2441 IISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDI 2500 Query: 1466 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1525 A+ N ++ SDK+YR +E+ + YD +DAIP + A+ASREIAS+++YKE F + G Sbjct: 2501 VLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLG 2560 Query: 1526 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1585 IG R+++DDP+M ++V ++QSD EYKKDF K +++F S D G++ AK+ Q L S Sbjct: 2561 HHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVS 2620 Query: 1586 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR 1645 DV Y+ L Q TC P+Q + HA++A+ LQSD YKSDL +G+GW GS + E +R Sbjct: 2621 DVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKR 2680 Query: 1646 AAEL 1649 A ++ Sbjct: 2681 ATQI 2684 Score = 1021 bits (2641), Expect = 0.0 Identities = 601/1615 (37%), Positives = 942/1615 (58%), Gaps = 85/1615 (5%) Query: 62 NTFTSVYHTPLN-LNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDK---EGAPNRQPL 117 NT TS YHTP + L+V +A + I + K + H + D E N + Sbjct: 2108 NTKTS-YHTPADMLSVTAAKDAQANITNTN----YKHLIHKYILLPDAMNIELTRNMNRI 2162 Query: 118 ANERAYWTGYGE---GNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAM- 173 ++ Y Y E G W P + E +A+K+ + Y Q F + Sbjct: 2163 QSDNEYKQDYNEWYKGLGWSPAGSLEVE-----KAKKATEYASDQKYRQHPSNFQFKKLT 2217 Query: 174 ----ITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYT 229 + A Q A N+ +++ + ++ + DTP++L++K L S Y Sbjct: 2218 DSMDMVLAKQNAHTMNKHLYTIDWNKDK----TKIHVMPDTPDILQAKQNQTLYSQKLYK 2273 Query: 230 EDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMR---GMAGPAIGAEGIL 286 +E+ KG + + Q+AK + ++ASD +Y Q Y+K++ G + +L Sbjct: 2274 LGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVL 2333 Query: 287 TRECAD-QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAA 345 + A Q + Y +++E+ + K S P + AKK EL SD+ Y+ ++ Sbjct: 2334 SMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQELVSDVDYKNYLHQ----- 2387 Query: 346 HYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLAS 405 + LP Q+++V QA+ V +L SEN YK + + G+G +GSL + Sbjct: 2388 -WTCLPDQNDVV--QAKKVYELQSENLYKSDLE-----WLRGIGWS-------PLGSLEA 2432 Query: 406 NVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQA 465 +A +I+ + YRQ D+ K++S+ D IV A Sbjct: 2433 EKNKRAS---EIIS---------------------EKKYRQPPDRNKFTSIPDAMDIVLA 2468 Query: 466 KINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFE 525 K NA+ S YR ++K+K + D P +V AK N S+ Y+ G+E+ K KG++ Sbjct: 2469 KTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYD 2528 Query: 526 MKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVE 581 + +DA+ + AAKAS E+AS KYKE + K G +G D +++ S+ +AK+ S+ E Sbjct: 2529 LPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDRE 2588 Query: 582 YKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYG 641 YKK FE+ KT+F P+DM+ + AKK QTL SD+DY+ LH++T LP+ A++AY Sbjct: 2589 YKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYD 2648 Query: 642 LQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQM 701 LQS+ YK+DL W+KG+GW+T GSL E+ K+A Q++S+ YRQ D+ KF+S+ DS M Sbjct: 2649 LQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPM 2708 Query: 702 EHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAK 761 AK + + Y ++ I D P L A+ N N SEKLYK E K K Sbjct: 2709 VLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRK 2768 Query: 762 GFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQS 821 G+++R+D++ AAKA RD+ASE KYKE Y + G IGA+ ++ D +M S+ ++K+QS Sbjct: 2769 GYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQS 2828 Query: 822 ELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKK 881 + EYKK FE K++ +DM+ +V A+K Q L +DV YK H +T LP V A++ Sbjct: 2829 DREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQ 2888 Query: 882 AYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDT 941 AY LQSDN Y++D++WM+G+GWV+ GSL+VE+ K+A E++S+K YRQ PD KFTS+ D+ Sbjct: 2889 AYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDS 2948 Query: 942 PEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKL 1001 E V A+ + RLY E + K D PE++LA+ N +N SET YK + + Sbjct: 2949 LEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANEEA 3008 Query: 1002 RDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATS 1061 + GY LR DA+P AAKAS ++ISDYKYK+ + K G +G+R++EDD + S++ Sbjct: 3009 KKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAK 3068 Query: 1062 LQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSC 1121 +QSD YKK FE K +F P+DM +V AKK QTL S+ DYK+ L ++T L + + Sbjct: 3069 IQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIH 3128 Query: 1122 AKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAV 1181 A++A+ LQS+N+Y+SDL ++RG+ V G++++ K+A+E++S++ YRQ P K+T+V Sbjct: 3129 ARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSV 3188 Query: 1182 TDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESW 1241 TD+ + AK + N+RLY A + + + + PE + A+ N N S++ Y+++ Sbjct: 3189 TDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAM 3248 Query: 1242 RNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRR 1301 + +GY L +A+P AA+AS DIASD+ Y+ + K+ G IG ++V DDP+I Sbjct: 3249 EEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLH 3308 Query: 1302 MGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLK 1361 + ++QS+ +Y++ + ++ P+DM+ +V AK Q L SD DY+ H++ LP+ Sbjct: 3309 IAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQND 3368 Query: 1362 MAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKF 1421 + A+KA+ LQS+ YKSDL MKGIGW+ + S ++ AK+AGEL+S+T YR++P+++KF Sbjct: 3369 IIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKF 3428 Query: 1422 TTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDK 1478 T++ D+P+ V AKN+ ++ N+R+Y D +++H ++PD P+ A+LN ++ SDK Sbjct: 3429 TSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIH---VMPDTPEIMLAKLNRINYSDK 3485 Query: 1479 VYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPR 1538 +Y+ + E+++ YD RLDAIP Q A+ASR+IASD++YKE + + G IG R++ DDP+ Sbjct: 3486 LYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPK 3545 Query: 1539 MKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTC 1598 M ++V ++QSD EYKK+F K +++F S D G++ AK+ Q L SD+ Y+ PL + TC Sbjct: 3546 MMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTC 3605 Query: 1599 DPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANAR 1653 P+Q + A+KA+ LQSD YKSDL RG+GW P GS +VE +RA E+ + R Sbjct: 3606 LPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDR 3660 Score = 1010 bits (2611), Expect = 0.0 Identities = 585/1584 (36%), Positives = 921/1584 (58%), Gaps = 86/1584 (5%) Query: 140 DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198 DP++V + K E EY +D+E+ + K S P + AKK +L S V+YK Sbjct: 2328 DPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQELVSDVDYKN--- 2383 Query: 199 ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANEL 258 + +++ + D +++++K +LQS+ Y D E RG G P A + KRA+E+ Sbjct: 2384 -YLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEK-NKRASEI 2441 Query: 259 ASDVRYHQQYQKEMRGMAGPAI----------GAEGILTRECADQ--------------- 293 S+ +Y Q + A+ L RE D+ Sbjct: 2442 ISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIV 2501 Query: 294 ---------YGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGA 344 + Y YEE + KG + + AK + E+AS+ KY++ F K G Sbjct: 2502 LAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGH 2561 Query: 345 AHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLA 404 H + +D+ + + V K+ S+ +YK++++ V M L A K +L Sbjct: 2562 -HIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQTLV 2619 Query: 405 SNVAYKADYKH---------DIVDYNYPATLTPS--YQTAMKLVP--------------- 438 S+V YK +Y H D++ L Y++ ++ + Sbjct: 2620 SDVDYK-NYLHQWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKN 2678 Query: 439 ------LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQ 492 L D YRQ D+ K+SS+ D+ +V AK NA ++H Y ++K+K + Sbjct: 2679 KRATQILSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMP 2738 Query: 493 DVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEY 552 D P+++ AK N +SE YK G E+ K KG++M++DA+ + AAKAS ++AS KYKE Y Sbjct: 2739 DTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGY 2798 Query: 553 EKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKA 608 K G +G D +++ S+ +AK+ S+ EYKK FE+ KT+F P+DM+ + AKK Sbjct: 2799 RKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKC 2858 Query: 609 QTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNL 668 QTL SD+DY+ LH++T LP+ A++AY LQS+ YK+DL WM+G+GW++ GSL++ Sbjct: 2859 QTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDV 2918 Query: 669 EQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYT 728 E+ K+A +++S+K YRQ D KFTSVTDS + AK + + Y ++ Q Sbjct: 2919 EKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIH 2978 Query: 729 ISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYK 788 I D P + AR N N SE LYK + E K KG++LR D++ +AAKA RD+ S+ KYK Sbjct: 2979 IMPDTPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYK 3038 Query: 789 EDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHA 848 + Y + G IGA++++ D +M S+ ++K+QS+ EYKK FE K++ +DM+ +V A Sbjct: 3039 DGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLA 3098 Query: 849 RKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGS 908 +K Q L +DV YK H +T LP V A++AY LQSDN Y++D++W++G+GWV GS Sbjct: 3099 KKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGS 3158 Query: 909 LNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKH 968 ++V + K+A E++S+ YRQ PD LKFTS+ D+ E V A+ + RLY E + K Sbjct: 3159 MDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKT 3218 Query: 969 HYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDY 1028 D PE++LA+ N +N SE+ Y+++ + + GY LR DA+P AAKAS +I SDY Sbjct: 3219 QVHIMPDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDY 3278 Query: 1029 KYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAAL 1088 KYKEA+ K G +G+R++ DD + S++ +QSD YKK FE K ++ P+DM + Sbjct: 3279 KYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGI 3338 Query: 1089 VHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVI 1148 V AKK QTL S+ DYKHPL ++ L + + A+KA+ LQS+NLY+SDL +M+G+ V Sbjct: 3339 VLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVP 3398 Query: 1149 PGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGED 1208 +LE+ K+A EL+S++ YRQ P + K+T++TDTP + AK + N+RLY A ++ Sbjct: 3399 IDSLEVVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDN 3458 Query: 1209 ARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIA 1268 + + PE + AK N N SD YK + + +GY L ++A+P QAA+AS DIA Sbjct: 3459 DKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIA 3518 Query: 1269 SDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDM 1328 SD+ Y+ + K+ G IG ++++DDP++ + ++QS+ +Y++ + +F P+DM Sbjct: 3519 SDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDM 3578 Query: 1329 VHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIG 1388 + +V AK Q L SD DY+ H++T LP+ + A+KA+ LQS+ YKSDL ++GIG Sbjct: 3579 LGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIG 3638 Query: 1389 WLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR-- 1446 W+ + S ++E K+AGE++S+ KYR+ D +KFT + D+P++V AKN+ + ++ +Y Sbjct: 3639 WVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEA 3698 Query: 1447 -SGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTAR 1505 D S+H ++PD PD A+ N+ ++S K+Y W++++ YD R DAI ++A+ Sbjct: 3699 WDADKTSIH---VMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAK 3755 Query: 1506 ASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQF 1565 ASR+IASD++YKEA+ + +G IG +S++DDP++ ++ G++QS+ EYKK+F K +++F Sbjct: 3756 ASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKF 3815 Query: 1566 HSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLN 1625 S D +L AK+ Q L +D+ YR L + TC P+Q + A+KA+ LQSD YK+DL Sbjct: 3816 SSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLE 3875 Query: 1626 LTRGVGWTPPGSYKVEMARRAAEL 1649 RG+GW P GS +V + A + Sbjct: 3876 WLRGIGWMPQGSPEVLRVKNAQNI 3899 Score = 968 bits (2502), Expect = 0.0 Identities = 577/1617 (35%), Positives = 917/1617 (56%), Gaps = 88/1617 (5%) Query: 109 EGAPNRQPLANERAYWTGYGEGNAWCPGAL---PDPEIVRMVEARKSLGE-EYTEDYEQP 164 + A + +A+E Y G+ + GA DP+++ + K + EY +D+E+ Sbjct: 2537 KAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKW 2596 Query: 165 RGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQS 224 + K S P + AKK L S V+YK + +++ + D +++ ++ LQS Sbjct: 2597 KTKFSSPVDMLGVVL-AKKCQTLVSDVDYKN----YLHQWTCLPDQSDVIHARQAYDLQS 2651 Query: 225 DVRYTEDYEQQRGKG-------------------------------SFPAMITPAYQIAK 253 D Y D + +G G F +++ + Sbjct: 2652 DNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLA 2711 Query: 254 RANELASDVR-YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQG-YPEEYEEHRGKGSF 311 + N + + R Y + + K+ + E +L ++ Y + Y EE + KG Sbjct: 2712 KNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYD 2771 Query: 312 PAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEN 371 + + AK + ++AS+ KY++ + K G H + +D+ + + V K+ S+ Sbjct: 2772 MRVDAIPIKAAKASRDIASEFKYKEGYRKQLGH-HIGARAIRDDPKMMWSMHVAKIQSDR 2830 Query: 372 KYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKH---------DIVDYN- 421 +YK++++ V M L A K +L S+V YK +Y H D++ Sbjct: 2831 EYKKDFEKWKTKFSSPVDMLGVVL-AKKCQTLVSDVDYK-NYLHQWTCLPDQSDVIHARQ 2888 Query: 422 -YPATLTPSYQTAMKLVP---------------------LKDANYRQSIDKLKYSSVTDT 459 Y Y++ ++ + L D YRQ D+ K++SVTD+ Sbjct: 2889 AYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDS 2948 Query: 460 PQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKT 519 + V AK NA ++ Y ++K+K + D P+++ A+ N +SE YK E+ Sbjct: 2949 LEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANEEA 3008 Query: 520 KGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAK 575 K KG++++ DA+ ++AAKAS ++ S+ KYK+ Y K G +G D +++ S+ +AK Sbjct: 3009 KKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAK 3068 Query: 576 MSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQW 635 + S+ EYKK FE+ KT+F P+DM+ + AKK QTL SD+DY+ LHE+T LP+ Sbjct: 3069 IQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIH 3128 Query: 636 AKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSV 695 A++AY LQS+ YK+DL W++G+GW+ GS+++ + K+A +++S+ YRQ D+LKFTSV Sbjct: 3129 ARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSV 3188 Query: 696 TDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSW 755 TDS + AK + + Y ++ Q I D P + AR N N SE LY+ + Sbjct: 3189 TDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAM 3248 Query: 756 ENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQ 815 E K +G++LR D++ +AAKA RD+AS+ KYKE Y + G IGA+ V D ++ SL Sbjct: 3249 EEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLH 3308 Query: 816 MSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMK 875 ++K+QS+ EYKK FE K++ +DM+ +V A+K Q L +DV YK H + LP Sbjct: 3309 IAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQND 3368 Query: 876 VEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKF 935 + A+KAY LQSDN Y++D++WMKG+GWV SL V +AK+AGEL+S+ YRQ P+ LKF Sbjct: 3369 IIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKF 3428 Query: 936 TSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYK 995 TSI DTPE V A+ + RLY E +N K D PE++LAKLN +N S+ YK Sbjct: 3429 TSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYK 3488 Query: 996 ESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAH 1055 + + + GY LRLDA+P QAAKAS +I SDYKYKE + K G +G+R+++DD + Sbjct: 3489 LALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMW 3548 Query: 1056 SVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAE 1115 S++ +QSD YKK FE K +F P+DM +V AKK Q L S+ DYKHPL ++T L + Sbjct: 3549 SIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPD 3608 Query: 1116 DLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHS 1175 + A+KA+ LQS+ +Y+SDL ++RG+ V G++E+E K+A E++S+ KYRQ Sbjct: 3609 QNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQ 3668 Query: 1176 FKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDA 1235 K+T +TDTP ++ AK + ++ LY A + + + P+ + AK+N+AN+S Sbjct: 3669 LKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQK 3728 Query: 1236 RYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPR 1295 Y + W + + Y L +A+ ++A+AS DIASD+ Y+ + K++G IG QS+ DDP+ Sbjct: 3729 LYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPK 3788 Query: 1296 IQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTA 1355 I G++QSE +Y++ + +F P+DM+ ++ AK Q L +D DYR H++T Sbjct: 3789 IMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTC 3848 Query: 1356 LPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKK 1415 +P+ + AKKA+ LQS+ YK+DL ++GIGW+ SP++ K A + ++ YR Sbjct: 3849 MPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDSVYRTP 3908 Query: 1416 PDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTRARLNA 1472 ++K+T++VD+P++V AK++ + + YR D S+H ++PD P+ AR NA Sbjct: 3909 VVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIH---IMPDTPEINLARANA 3965 Query: 1473 LHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRS 1532 L++S+K+YR W++ +AG D RLDAIP Q A+ASREIASD++YK + +G +G + Sbjct: 3966 LNVSNKLYREGWDEMKAGC-DVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYVGTLT 4024 Query: 1533 VDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQP 1592 DD +++ L +LQ++ EY+ D+AK +++ S D +L +K SQ L SD+ YR Sbjct: 4025 ARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNY 4084 Query: 1593 LPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1649 L Q TC P+Q + A+KA++LQSD YK+DL RG+GW P S V A+ AA++ Sbjct: 4085 LHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAADI 4141 Score = 957 bits (2475), Expect = 0.0 Identities = 594/1718 (34%), Positives = 929/1718 (54%), Gaps = 141/1718 (8%) Query: 55 HAHNPKNNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHW--DMKS--KDKEG 110 + +P FTS+ +P+ + + + +S I + GE K + D+ + K Sbjct: 1228 YRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCN 1287 Query: 111 APNRQPLANERAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEE--YTEDYEQPRGK- 167 A N + +R + +GN A+P + +A +++ + Y E YE+ +GK Sbjct: 1288 AYNISDVCYKRDWHDLIAKGNNVLGDAIP----ITAAKASRNIASDYKYKEAYEKSKGKH 1343 Query: 168 -GSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDV 226 G P +L S EYK+ ++ T TP + S A++ DV Sbjct: 1344 VGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENT----KTSYHTPGDMVSITAAKMAQDV 1399 Query: 227 RYTEDYEQQRGKGSF--PAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEG 284 +Y+Q ++ AM + + + N++ SD Y +Y ++G+ IG+ Sbjct: 1400 ATNVNYKQPLHHYTYLPDAM---SLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGS-- 1454 Query: 285 ILTRECADQYGQGYPE-EYEEHRGKGSFPAM-----ITPAYQNAKKAHEL---------- 328 L E + G E +Y +H F ++ + A N K+ +L Sbjct: 1455 -LEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLK 1513 Query: 329 ---------------------ASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKL 367 SD Y+ D+ K A Y P D + + A+S + Sbjct: 1514 HKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTI-AKGYDLRP--DAIPIVAAKSSRNI 1570 Query: 368 VSENKYKENYQNHMRGRYEG---VGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPA 424 S+ KYKE Y+ +G+ G + D + +H M V + S+ YK Y+ Y+ P Sbjct: 1571 ASDCKYKEAYEK-AKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPL 1629 Query: 425 TLTPSYQTAMKLVPLKDANYRQSI-----------------------DKLKYSSVT---- 457 + +ANYRQS D L S T Sbjct: 1630 DMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMK 1689 Query: 458 -------DTPQIVQAKINAQQLSHVNYRADYEK-----------------NKLN-----Y 488 ++ ++ +AK + LS YR EK NKLN Y Sbjct: 1690 GIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLY 1749 Query: 489 T-----------LPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAK 537 T + D P ++ ++ N S+ YK GWE+ K KG++++ DA+++ AA+ Sbjct: 1750 TEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAAR 1809 Query: 538 ASGELASNIKYKEEYEKTKGKAMG----TADSRLLHSLQIAKMSSEVEYKKGFEESKTRF 593 AS ++AS+ KYK+ YE+ KGK +G D +L+H +Q+AKM S+ EYKKG+E+SKT F Sbjct: 1810 ASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSF 1869 Query: 594 HLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLA 653 H P+DM+++ AKK+Q +A++ +YR +H Y +LP+ M + AK +QS+ QYKAD A Sbjct: 1870 HTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYA 1929 Query: 654 -WMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQS 712 +MKG+GWL GSL E+ KKA +++SEK YRQ D LK++++ DS M A+ + ++ + Sbjct: 1930 DFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMN 1989 Query: 713 GVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTF 772 YK E + I D P + A+ANA N+S+KLYK S E K KG++LR D++ Sbjct: 1990 EHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIPI 2049 Query: 773 LAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDT 832 AAKA RD+AS+ KYK +YE+ +GK++G + ++ D ++ HS+Q++K+QS+ EYKK +E+T Sbjct: 2050 KAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENT 2109 Query: 833 KSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYR 892 K+ H DM+ + A+ AQ T+ YK H + LP M +E + +QSDN+Y+ Sbjct: 2110 KTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYK 2169 Query: 893 ADV-KWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISY 951 D +W KG+GW GSL VE+AKKA E S++KYRQHP +F + D+ +MV A+ + Sbjct: 2170 QDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNA 2229 Query: 952 TQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLD 1011 LY K D P++L AK N S+ YK W + GY L +D Sbjct: 2230 HTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVD 2289 Query: 1012 ALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKG 1071 A+ Q AKAS +I SDYKYK+ + K G +G RSL+DD L S+ +QS+ YKK Sbjct: 2290 AISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKD 2349 Query: 1072 FEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSE 1131 FE K +F P+DM +V AKK Q L S+ DYK+ L Q+T L + + AKK ++LQSE Sbjct: 2350 FEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSE 2409 Query: 1132 NLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAK 1191 NLY+SDL ++RG+ G+LE E K+ASE+ISE KYRQ P K+T++ D +++ AK Sbjct: 2410 NLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAK 2469 Query: 1192 FSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKL 1251 + + ++RLY+ A + + + + P+ + AK N N SD Y+ + L+ +GY L Sbjct: 2470 TNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDL 2529 Query: 1252 TIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQY 1311 ++A+P +AA+AS +IAS++ Y+ F K+ G IG +++ DDP++ + ++QS+ +Y Sbjct: 2530 PVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREY 2589 Query: 1312 RRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHAL 1371 ++ + +F P+DM+ +V AK Q L SD DY+ H++T LP+ + A++A+ L Sbjct: 2590 KKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDL 2649 Query: 1372 QSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLV 1431 QS+ YKSDL +KGIGW+ S + E K+A +++S+ YR+ PD KF++++DS +V Sbjct: 2650 QSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMV 2709 Query: 1432 HAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGS 1491 AKN+ + N R+Y + ++PD P+ A+ N ++ S+K+Y+ E+ + Sbjct: 2710 LAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKG 2769 Query: 1492 YDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSD 1551 YD R+DAIP + A+ASR+IAS+F+YKE + + G IG R++ DDP+M ++V ++QSD Sbjct: 2770 YDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSD 2829 Query: 1552 NEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKA 1611 EYKKDF K +++F S D G++ AK+ Q L SDV Y+ L Q TC P+Q + HA++A Sbjct: 2830 REYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQA 2889 Query: 1612 HQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1649 + LQSD YKSDL RG+GW GS VE +RA E+ Sbjct: 2890 YDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEI 2927 Score = 803 bits (2075), Expect = 0.0 Identities = 475/1446 (32%), Positives = 793/1446 (54%), Gaps = 35/1446 (2%) Query: 229 TEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTR 288 T DYEQ + S PA+ PA +A+ A+ + R + + + P I ++ Sbjct: 39 TSDYEQS--ETSKPALAQPA--LAQPASAKPVERRKVIRKKVDPSKFMTPYIAH----SQ 90 Query: 289 ECADQYGQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHY 347 + D + Y E++E+ +G+ TP + KK + S++KYR D + K H Sbjct: 91 KMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHV 150 Query: 348 HSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNV 407 A+D ++ A+ V++ VS+ YK+N+++ + +Y + A+K ++ S Sbjct: 151 DE-KAKD---IEHAKKVSQQVSKVLYKQNWED-TKDKYLLPPDAPELVQAVKNTAMFSKK 205 Query: 408 AYKADYKHDIVDYNYPATLTPSY-QTAMKLVPLKDANYRQSI--DKLKYSSVTDTPQIVQ 464 Y D++ D YP +P + A L D Y++ + + +++ + D P I Sbjct: 206 LYTEDWEAD-KSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEF 264 Query: 465 AKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGF 524 AK Q+S Y+ DYE ++ A+ NA S KY+E +E K + + Sbjct: 265 AKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQIY 324 Query: 525 EMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKA----MGTADSRLLHSLQIA-KMSSE 579 M+ + K +G AS +KYKE+YEK KGKA + +++ L L+ A S+ Sbjct: 325 FMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSD 384 Query: 580 VEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKK-----LHEYTVLPEDMKTQ 634 YK+ +E++K + + + Q +SD Y+ L Y ED Sbjct: 385 KLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHS 444 Query: 635 WAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTS 694 K S+ YKA+ +G G+ + +A K + Y+ D+ KFT Sbjct: 445 HCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTQ 504 Query: 695 VTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSS 754 VTDS + A+ + + S + YKA +E + I D P F+Q + NA NLS+ LYK Sbjct: 505 VTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSDNLYKQD 564 Query: 755 WENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSL 814 WE KAK F++++D++ LAAKA S+V YK+DYE+++GK+IG + D +M HSL Sbjct: 565 WEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSL 624 Query: 815 QMSKLQSELEYKKGFEDTKSQ----CHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL 870 +++K QS+ YK+ +E TK++ C + ++ D+ K H+ Sbjct: 625 KVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSEARYKDLYVKDVLGHYVGS 684 Query: 871 PTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHP 930 D K SD Y+A+ + KG + +A K + + Y+ HP Sbjct: 685 MEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKLDQCKDHTYKVHP 744 Query: 931 DALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNIS 990 D KFT++ D+P ++QA+++ Q D Y+ + E K AD P+ + ++NA N+S Sbjct: 745 DKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRVNAYNLS 804 Query: 991 ETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1050 + YK+ W K + + +++DA+P AAKA+ + SD YK+ +EK KG+M+G+ S+ DD Sbjct: 805 DNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDD 864 Query: 1051 ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQY 1110 + HS+ QSD Y+K +E SK + PLDM + AKK+Q +AS+ DYKH L Y Sbjct: 865 PKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHILHSY 924 Query: 1111 TSLAEDLRLSCAKKAHKLQSENLYRSDLN-FMRGVACVIPGTLEIEGRKKASELISESKY 1169 + + + + AKKA+ LQS+ Y++D N +M+G V G+LE+E K+AS++++E KY Sbjct: 925 SYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAKRASDILNEKKY 984 Query: 1170 RQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNA 1229 RQHP + K+T++ D P + +K + ++ YKA GE+ H+Y + LP+FI+AK NA Sbjct: 985 RQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNA 1044 Query: 1230 ANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQS 1289 N+S+ YK ++L +GY L +A+P +AA+A+ ASD Y+ D+ K +GK++G QS Sbjct: 1045 YNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQS 1104 Query: 1290 VRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQ 1349 ++DDP++ H + ++QS+ +Y++ ++++++ P DM ++V AK AQ + S+ +Y+ Sbjct: 1105 LQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVSNVNYKHS 1164 Query: 1350 YHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIGWLALRSPQMESAKKAGELIS 1408 H +T LP+ + + +K +QS+ YK D MKGIGW+ + S +E KKAG+ ++ Sbjct: 1165 LHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGDALN 1224 Query: 1409 ETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRA 1468 E KYR+ PD++KFT++VDSP +V AK + ++ +Y++ + H+YT+ PD P F +A Sbjct: 1225 EKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQA 1284 Query: 1469 RLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQI 1528 + NA ++SD Y+ W A + DAIP A+ASR IASD++YKEA+ + +G + Sbjct: 1285 KCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKGKHV 1344 Query: 1529 GYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVH 1588 G+RS+ DDP++ H++NV +LQSD EYKK++ +++ +H+ D + AK +Q +A++V+ Sbjct: 1345 GFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVATNVN 1404 Query: 1589 YRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLN-LTRGVGWTPPGSYKVEMARRAA 1647 Y+QPL T P+ + L H + +Q+QSD YK + N +G+GW P GS +VE ++A Sbjct: 1405 YKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVKKAG 1464 Query: 1648 ELANAR 1653 + N R Sbjct: 1465 DALNER 1470 Score = 754 bits (1947), Expect = 0.0 Identities = 490/1577 (31%), Positives = 813/1577 (51%), Gaps = 95/1577 (6%) Query: 140 DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198 DP+I+ + K + EY +D+E+ + + S P + AKK L S V+YK Sbjct: 3300 DPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDML-GIVLAKKCQTLVSDVDYKHPLH 3358 Query: 199 ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANEL 258 E I + D +++ ++ LQSD Y D E +G G P + AKRA EL Sbjct: 3359 EWIC----LPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVR-AKRAGEL 3413 Query: 259 ASDVRYHQQYQK----------EMRGMAGPAIGAEGILTRECADQYGQG----------- 297 SD Y Q+ + E A+ L E D + Sbjct: 3414 LSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIM 3473 Query: 298 -------------YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGA 344 Y EE + +G + Q AK + ++ASD KY++ + K G Sbjct: 3474 LAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGH 3533 Query: 345 AHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLA 404 H + +D+ + + V K+ S+ +YK+ ++ V M L A K L Sbjct: 3534 -HIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVL-AKKCQILV 3591 Query: 405 SNVAYKADYKHDIVDYN--------------YPATLTPSYQTAMKL------VP------ 438 S++ DYKH + ++ Y Y++ ++ VP Sbjct: 3592 SDI----DYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEV 3647 Query: 439 ---------LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYT 489 L D YRQ D+LK++ +TDTP+IV AK NA +S Y ++ +K + Sbjct: 3648 EKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIH 3707 Query: 490 LPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYK 549 + D P ++ AK+N+ S+ Y +GW+++K K ++++ DA+S+ +AKAS ++AS+ KYK Sbjct: 3708 VMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYK 3767 Query: 550 EEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHA 605 E YEK KG +G D +++ ++ K+ SE EYKK F++ KT+F P+DM++I A Sbjct: 3768 EAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLA 3827 Query: 606 KKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGS 665 KK QTL +D+DYR LHE+T +P+ AKKAY LQS+ YKADL W++G+GW+ +GS Sbjct: 3828 KKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGS 3887 Query: 666 LNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVH 725 + + K A + + YR V LK+TS+ D+ ++ AK + E S Y+ ++ Sbjct: 3888 PEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKT 3947 Query: 726 QYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEV 785 I D P ARANA N+S KLY+ W+ KA G ++RLD++ AAKA R++AS+ Sbjct: 3948 SIHIMPDTPEINLARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDY 4006 Query: 786 KYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHL 845 KYK D+E+ +G +G + D+++ +L KLQ+E EY+ + K++ +DM+ + Sbjct: 4007 KYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSI 4066 Query: 846 VHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVA 905 +H++ +Q L +D+ Y+ H +T +P V AKKAY LQSDN Y+AD++W++G+GW+ Sbjct: 4067 LHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMP 4126 Query: 906 TGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGEN 965 S++V AK A ++ SEKKYR + L FT + D + V A+ S D YR+ Sbjct: 4127 NDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNA 4186 Query: 966 IKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEII 1025 K YT T + P + A+ A + + YKE W + + GY L DA+PF A ++ Sbjct: 4187 TKSKYTLT-ETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQ 4245 Query: 1026 SDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDM 1085 S+ KYK K KG +G ++ DD L +A +Q++ YK+ + +KA+ ++P DM Sbjct: 4246 SELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADM 4305 Query: 1086 AALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVA 1145 +++ AK+ QTL S+ DY++ L Q+ + + A+KA+ LQS+N+YR+DL ++RG+ Sbjct: 4306 VSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIG 4365 Query: 1146 CVIPGTLEIEGRKKASELISESKYRQH--PHSFKYTAVTDTPNLLHAKFSNQITNERLYK 1203 + +++ K E++S+ KY+++ + + +V D P ++ AK ++ ++ YK Sbjct: 4366 WIPLDSVDHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYK 4425 Query: 1204 AAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARA 1263 A+ +YT + P +K S YK +W +A GY L +P A+ Sbjct: 4426 ETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKH 4485 Query: 1264 SGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFH 1323 + + S+ Y+ + K++G + + + + P + HC +++S L YR+ ++A H Sbjct: 4486 ADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVH 4545 Query: 1324 LPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG 1383 +P DM++ V AK Q + SD +YR +H++T+L E+ + + A + S+ YK DL Sbjct: 4546 IPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNW 4605 Query: 1384 MKGIGWLALRSPQMESAKKAGELISETKYRK--KPDSIKFTTVVDSPDLVHAKNSYMHCN 1441 +KGIG +PQ+ AKK+ +L S+ +Y K + + V D+P V A S ++ + Sbjct: 4606 LKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINAS 4665 Query: 1442 ERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPF 1501 E Y+ + +YT + + D+ R R S +Y+ +W++ +A SY + Sbjct: 4666 EVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSL 4725 Query: 1502 QTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKS 1561 A+ + +AS +Y+E + + + L RSVDDDP L VG+L D Y+ + K+ Sbjct: 4726 THAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKN 4785 Query: 1562 RSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYK 1621 + + H D ++ AK SQ+ S++ YR L + C P+ H +K SD+ YK Sbjct: 4786 KMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYK 4845 Query: 1622 SDLNLTRGVG---WTPP 1635 DLN +G+G W P Sbjct: 4846 DDLNWLKGIGCYVWDTP 4862 Score = 721 bits (1862), Expect = 0.0 Identities = 536/1837 (29%), Positives = 900/1837 (48%), Gaps = 212/1837 (11%) Query: 38 MMLSVNNFVSHQKKPYCHAHNPKNNTFTSVYHTPLNL----NVRTFPEAISGIHDQEDGE 93 M+L+ NN ++ + Y A + T + TP L N + E + + +E Sbjct: 2708 MVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKR 2767 Query: 94 QCKSVFHWDMK--SKDKEGAPNRQPLANERAYWTGYGEGNAWCPGALP---DPEIVRMVE 148 + +DM+ + + A + +A+E Y GY + GA DP+++ + Sbjct: 2768 K-----GYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMH 2822 Query: 149 ARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTV 207 K + EY +D+E+ + K S P + AKK L S V+YK + +++ + Sbjct: 2823 VAKIQSDREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQTLVSDVDYKN----YLHQWTCL 2877 Query: 208 VDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQ 267 D +++ ++ LQSD Y D + RG G + ++ + + KRA E+ SD Y Q Sbjct: 2878 PDQSDVIHARQAYDLQSDNMYKSDLQWMRGIG-WVSIGSLDVEKCKRATEILSDKIYRQP 2936 Query: 268 ---------------------------------YQKEMRGMAGPAIGAEGILTRECADQY 294 + K+ + E +L R+ Y Sbjct: 2937 PDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINY 2996 Query: 295 GQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ 353 + Y EE + KG AK + ++ SD KY+ + K G H + + Sbjct: 2997 SETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGH-HIGARNIE 3055 Query: 354 DNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADY 413 D+ + + V K+ S+ +YK++++ V M L A K +L S+V YK +Y Sbjct: 3056 DDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQTLVSDVDYK-NY 3113 Query: 414 KHD---IVDYNYPATLTPSYQT----------------------AMKLVPLK-------D 441 H+ + D N +Y +M +V K D Sbjct: 3114 LHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSD 3173 Query: 442 ANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAK 501 YRQ DKLK++SVTD+ + V AK NA ++ Y ++K+K + D P+++ A+ Sbjct: 3174 NIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLAR 3233 Query: 502 TNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMG 561 N +SE Y++ E+ K +G++++ DA+ ++AAKAS ++AS+ KYKE Y K G +G Sbjct: 3234 QNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIG 3293 Query: 562 TA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDY 617 D +++ SL IAK+ S+ EYKK FE+ KTR+ P+DM+ I AKK QTL SD+DY Sbjct: 3294 ARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDY 3353 Query: 618 RKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQL 677 + LHE+ LP+ A+KAY LQS+ YK+DL WMKG+GW+ SL + +AK+AG+L Sbjct: 3354 KHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGEL 3413 Query: 678 VSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFL 737 +S+ YRQR + LKFTS+TD+ + AK + + Y + + D P + Sbjct: 3414 LSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIM 3473 Query: 738 QARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGK 797 A+ N N S+KLYK + E K +G++LRLD++ AAKA RD+AS+ KYKE Y + G Sbjct: 3474 LAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGH 3533 Query: 798 LIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATD 857 IGA++++ D +M S+ ++K+QS+ EYKK FE K++ +DM+ +V A+K Q L +D Sbjct: 3534 HIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSD 3593 Query: 858 VGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKA 917 + YK H +T LP V A+KAY LQSD Y++D++W++G+GWV GS+ VE+ K+A Sbjct: 3594 IDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRA 3653 Query: 918 GELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLP 977 GE++S++KYRQ D LKFT I DTPE+V A+ + LY E + K D P Sbjct: 3654 GEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTP 3713 Query: 978 EVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKM 1037 ++LLAK N+ NIS+ Y + W + + Y LR DA+ ++AKAS +I SDYKYKEA+EK Sbjct: 3714 DILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQ 3773 Query: 1038 KGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTL 1097 KG +G++S+EDD + +++A +QS+ YKK F+ K +F P+DM +++ AKK QTL Sbjct: 3774 KGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTL 3833 Query: 1098 ASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGR 1157 ++ DY++ L ++T + + + AKKA+ LQS+ LY++DL ++RG+ + G+ E+ Sbjct: 3834 VTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRV 3893 Query: 1158 KKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTL 1217 K A + +S YR + KYT++ DTP ++ AK + + + Y+ + + + Sbjct: 3894 KNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMP 3953 Query: 1218 GLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFL----- 1272 PE A+ NA N+S+ Y+E W ++A G + ++A+P QAA+AS +IASD+ Sbjct: 3954 DTPEINLARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDH 4012 Query: 1273 ---------------------------------YRHDFVKERGKLIGPQSVR-------- 1291 YR D+ K + K+ P + Sbjct: 4013 EKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNS 4072 Query: 1292 --------------------DDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHL 1331 D + ++ +LQS+ Y+ + +P D V + Sbjct: 4073 QALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSV 4132 Query: 1332 VHAKNAQALASDHDYRTQYH--KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW 1389 HAK+A + S+ YRT+ FT + + + AK++ + +++Y+ D K + Sbjct: 4133 NHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKS-KY 4191 Query: 1390 LALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCN----ERMY 1445 +P + +A++A ++ + Y++ + K T + PD V +++ HCN E Y Sbjct: 4192 TLTETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAH-HCNDVQSELKY 4250 Query: 1446 RSGDAESLHRYTLIP---DHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQ 1502 ++ + Y +P D P ++++Y+ + +T+A + D + Sbjct: 4251 KAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKA-KINIPADMVSVL 4309 Query: 1503 TARASREIASDFRYKEAF---------------LRDRGLQ--------------IGYRSV 1533 A+ + + SD Y+ + LQ IG+ + Sbjct: 4310 AAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPL 4369 Query: 1534 DDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPL 1593 D ++ N + S +YKK+ ++ F S D P ++ AK + SDV Y++ Sbjct: 4370 DSVDHVRVTKNQ-EMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428 Query: 1594 PQP----TCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1649 + T P+ + H++ +L S + YK T+ G+T Y + + A+L Sbjct: 4429 NKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADL 4488 Query: 1650 ANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILH 1686 N+ + Y+ + G + +G+V + ++H Sbjct: 4489 VNS-----ELKYKETYEKQKGHYLAGKVIGEFPGVVH 4520 Score = 438 bits (1126), Expect = e-122 Identities = 403/1579 (25%), Positives = 694/1579 (43%), Gaps = 137/1579 (8%) Query: 156 EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLR 215 EY D+ + + K P + + +K + L S ++Y+ + +++ + D ++++ Sbjct: 4045 EYRLDWAKWKAKIQSPVDML-SILHSKNSQALVSDMDYRN----YLHQWTCMPDQNDVIQ 4099 Query: 216 SKAGAQLQSDVRYTEDYEQQRGKGSFP---------------------------AMITPA 248 +K +LQSD Y D E RG G P TP Sbjct: 4100 AKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPV 4159 Query: 249 -----YQIAKRANELASDVRYHQQYQ--KEMRGMAGPAIGAEGILTRECADQYGQGYPEE 301 Y AK++ E+ D++Y + + K + + DQY Y E Sbjct: 4160 DDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLHTAQEAARILDQYL--YKEG 4217 Query: 302 YEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPA-QDNLVLKQ 360 +E + G + +A +++ S++KY+ + K KG HY +P +D+ L Sbjct: 4218 WERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKG--HYVGVPTMRDDPKLVW 4275 Query: 361 AQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVG-SLASNVAYKADYKH---- 415 + ++ +E YKE+Y H + D ++ A K G +L S++ Y+ +Y H Sbjct: 4276 FEHAGQIQNERLYKEDY--HKTKAKINIPADMVSVLAAKQGQTLVSDIDYR-NYLHQWMC 4332 Query: 416 -----DIV----------DYNYPATLTPSYQTAMKLVPLKDANY------RQSIDKLKYS 454 D++ D Y A L + + +PL ++ ++ + ++KY Sbjct: 4333 HPDQNDVIQARKAYDLQSDNVYRADL--EWLRGIGWIPLDSVDHVRVTKNQEMMSQIKYK 4390 Query: 455 -----------SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTN 503 SV D P+IV AKIN+ S V Y+ + K K YT D P + +K Sbjct: 4391 KNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDM 4450 Query: 504 AKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG-----K 558 KL+S + YK WE TK G+ + + ++ AK + + S +KYKE YEK KG K Sbjct: 4451 GKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGK 4510 Query: 559 AMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYR 618 +G ++H L KM S + Y+K +E++K H+P DM+N AK+ Q + SDL+YR Sbjct: 4511 VIGEFPG-VVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYR 4569 Query: 619 KKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLV 678 H++T L E+ + A + S+ YK DL W+KG+G + + AKK+ L Sbjct: 4570 HYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQ 4629 Query: 679 SEKNYRQRVDE--LKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLF 736 S+ Y E + VTD+ A +S S V YK Q +YT + + Sbjct: 4630 SQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDY 4689 Query: 737 LQARANAANL-SEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSR 795 + R N NL S LYK +W+ KA + L +L+ AK ++ LAS +KY+E+YE+ + Sbjct: 4690 DRTR-NLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFK 4748 Query: 796 GKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLA 855 + V D + L++ KL + Y+ +E K + H+ DMV +V A+ +Q Sbjct: 4749 ALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKV 4808 Query: 856 TDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAK 915 +++ Y+ H + P + +K SD Y+ D+ W+KG+G + + AK Sbjct: 4809 SEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAK 4868 Query: 916 KAGELISEKKYRQHPDALK--FTSIKDTPEMVQARISYTQAVDRLYR-EQGENIKHHYTP 972 A +L + KY+ H + + + DTP VQA S Q D +Y + +++ P Sbjct: 4869 HAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAP 4928 Query: 973 ---TADLPEVLLA-KLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDY 1028 T DL L A KL + N+ YK S L GY+L D F+ K + + S + Sbjct: 4929 TTKTVDLDRALHAYKLQSSNL----YKTSLRTL-PTGYRLPGDTPHFKHIKDTRYMSSYF 4983 Query: 1029 KYKEAFEKMK--GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMA 1086 KYKEA+E K G LG + D+ H ++ S+ Y++ + K + H D Sbjct: 4984 KYKEAYEHTKAYGYTLGPK----DVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTP 5039 Query: 1087 ALVHAKKAQTLASNQDYKHPL----PQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMR 1142 + KK Q S YK SL ++ + + S+ Y+ DL ++ Sbjct: 5040 EIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLK 5099 Query: 1143 GVACVIPGTLEIEGRKKASELISESKYRQHPHSF--KYTAVTDTPNLLHAKFSNQITNER 1200 G C + T ++ + +L S Y KY V DTP + +E Sbjct: 5100 GFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSEL 5159 Query: 1201 LYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQA 1260 +Y+AAG+ + +T P+ +RAK S Y E R + + + Sbjct: 5160 VYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPH-HHAGNQTTALKH 5218 Query: 1261 ARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQA 1320 A+ D+ S+ Y+ + K + K V D P + +R S+L+Y+ ++ Sbjct: 5219 AKDVKDMVSEKKYKIQYEKMKDKY---TPVPDTPILIRAKRAYWNASDLRYKETFQKTKG 5275 Query: 1321 QFHLPMDMVHLVHAK----NAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELR 1376 ++H D + +V+ + + + +Y +Q + ++P+ + + S+++ Sbjct: 5276 KYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVK 5335 Query: 1377 YKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIK--FTTVVDSPDLVHAK 1434 YK DL +KGIG A +P A+K L S+ KY++ + K F V DSP H K Sbjct: 5336 YKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFK 5395 Query: 1435 NSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDF 1494 + NE+ YR+ + +Y L+ D P A+ +S YR ++E+++ Sbjct: 5396 YATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSI 5455 Query: 1495 RLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1554 +T + +++I SD YK + ++ GY ++ D P + H V SD +Y Sbjct: 5456 VDTPEHLRTTKVNKQI-SDILYKLEY--NKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKY 5512 Query: 1555 KKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTC----DPEQLGLRHAQK 1610 K+ + +++S D + AK + ++ +++ Y++ P++ A K Sbjct: 5513 KEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAK 5572 Query: 1611 AHQLQSDVKYKSDLNLTRG 1629 + QSD +YK D +G Sbjct: 5573 SSLQQSDFEYKLDREFLKG 5591 Score = 366 bits (939), Expect = e-100 Identities = 425/1743 (24%), Positives = 729/1743 (41%), Gaps = 256/1743 (14%) Query: 141 PEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196 P+ +++ARK+ + Y D E RG G P + + + R K ++ SQ++YK+ Sbjct: 4334 PDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIP-LDSVDHVRVTKNQEMMSQIKYKKN 4392 Query: 197 HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMI----------- 245 E F +VVD PE++ +K + QSDV+Y E + + +GK +F Sbjct: 4393 ALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDMGK 4452 Query: 246 -------------TPAYQI-----------AKRANELASDVRYHQQYQKEM-RGMAGPAI 280 T AY AK A+ + S+++Y + Y+K+ +AG I Sbjct: 4453 LYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVI 4512 Query: 281 GA-EGILTRECAD----QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYR 335 G G++ C D + Y + YE+ + P + + AK+ + SD++YR Sbjct: 4513 GEFPGVV--HCLDFQKMRSALNYRKHYEDTKANVHIPNDMMN-HVLAKRCQYILSDLEYR 4569 Query: 336 QDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTL 395 F++ + SL + N++ + ++ +++S+N YK++ N ++G V + L Sbjct: 4570 HYFHQ------WTSLLEEPNVI--RVRNAQEILSDNVYKDDL-NWLKGIGCYVWDTPQIL 4620 Query: 396 HAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSS 455 HA K L S + Y A K ++ +YN T TP Y TA Sbjct: 4621 HAKKSYDLQSQLQYTAAGKENLQNYNL-VTDTPLYVTA---------------------- 4657 Query: 456 VTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEG 515 VQ+ INA S V Y+ +Y + K YT + + + L+S YKE Sbjct: 4658 -------VQSGINA---SEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEA 4707 Query: 516 WEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA------DSRLLH 569 W++ K + + +SL AK LAS+IKY+EEYEK K A+ T D Sbjct: 4708 WDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFK--ALYTLPRSVDDDPNTAR 4765 Query: 570 SLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPE 629 L++ K++ + Y+ +E++K + H+ DMV + AK +Q S++DYR +LHE+ P+ Sbjct: 4766 CLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPD 4825 Query: 630 DMKTQ----------------------------W-------AKKAYGLQSELQYKADLAW 654 W AK AY L+ +++YKA + Sbjct: 4826 LQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLK 4885 Query: 655 MKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL---KFTSVTDSSQMEHAKKSQELQ 711 + L + QA K+G+ +S+ Y K T + ++ A + +LQ Sbjct: 4886 TRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQ 4945 Query: 712 SGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLT 771 S YK Y + D P F + S YK ++E+ KA G+ L + Sbjct: 4946 SSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPKDVP 5005 Query: 772 FLAAKAKRDLASEVKYKEDYERSRGKLIGAKD-------------------------VQG 806 F+ + ++ SE Y+E Y + + K+ D +QG Sbjct: 5006 FVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQG 5065 Query: 807 DS-------QMSHSLQMSKLQSELEYKKGFEDTKS-QCHV--SLDMVHLVHARK--AQHL 854 Q+ H + + S+++YK+ + K C + + DMV H RK + +L Sbjct: 5066 HMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYL 5125 Query: 855 ATDVGYKTAEHH----------------------------------FTALPTDMKVEWAK 880 TD K + + FT++P + AK Sbjct: 5126 YTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAK 5185 Query: 881 KAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALK--FTSI 938 + LQS Y + + ++ AK +++SEKKY+ + +K +T + Sbjct: 5186 RGQKLQSQYLYVELATKERPHHHAGNQTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPV 5245 Query: 939 KDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESW 998 DTP +++A+ +Y A D Y+E + K Y D +++ + +IS+ +YKE++ Sbjct: 5246 PDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENY 5305 Query: 999 SKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLED-DISLAHSV 1057 + G ++ D +A + +SD KYKE +KG +G + + D +LA Sbjct: 5306 MS-QLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKG--IGCYAYDTPDFTLAEK- 5361 Query: 1058 YATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQ----DYKHPLPQYTSL 1113 +L S YK+ FE +K+ F D H K A L + + DY+ +Y + Sbjct: 5362 -NKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLV 5420 Query: 1114 AEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHP 1173 ++ R AK A S+ YR + + I T E K ++ IS+ Y+ Sbjct: 5421 VDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQISDILYKLEY 5480 Query: 1174 HSFK---YTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAA 1230 + K YT + DTP LLH + ++ YK + + T+ AK Sbjct: 5481 NKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYK 5540 Query: 1231 NLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSV 1290 ++ YK+ + +A +K T + F A S SDF Y+ D +G + SV Sbjct: 5541 VNTNLDYKKQYEANKAH-WKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKL---SV 5596 Query: 1291 RDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQY 1350 DD R ++S+L+Y+ + H D ++ AK L S++ Y+ Sbjct: 5597 TDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHV 5656 Query: 1351 HK------FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIG--WLALRSPQMESAKK 1402 K +T LPE K+ S+ YK + KG + L P+++ A + Sbjct: 5657 KKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAME 5716 Query: 1403 AGELISETKYRKKP-DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDA-ESLHRYTLIP 1460 + S+ YRK +++ +TTV D PD+ A + +E YR+ E H +++ Sbjct: 5717 VAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSML- 5775 Query: 1461 DHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFR-LDAIPFQTARASREIASDFRYKEA 1519 PD A+ A S YR ++++ + + + D+ ++ + + +AS+ +YK Sbjct: 5776 GRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKAD 5835 Query: 1520 FLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKR 1579 + L + + M H LN +L S +YKK + KS+ +H+ D L K Sbjct: 5836 LKK---LHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKE 5892 Query: 1580 SQQLASDVHYRQPLP----QPTCDPEQLGLRHAQKAHQLQSDVKYKSDL-------NLTR 1628 + +L S V Y++ +P D E A+++ Q+QS +Y+ D NLT Sbjct: 5893 ATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLT- 5951 Query: 1629 GVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILHVK 1688 G+ T P V+ A + A R L+ + RG E D +AT+IL+ K Sbjct: 5952 GLEVT-PALLHVKYATKIASEKEYR-KDLEESIRGKGLTEMEDTPDMLRAKNATQILNEK 6009 Query: 1689 KKK 1691 + K Sbjct: 6010 EYK 6012 Score = 351 bits (901), Expect = 3e-96 Identities = 403/1632 (24%), Positives = 686/1632 (42%), Gaps = 177/1632 (10%) Query: 138 LPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196 L +P ++R+ A++ L + Y +D +G G + TP AKK+ L SQ++Y Sbjct: 4579 LEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCY-VWDTPQILHAKKSYDLQSQLQYTAA 4637 Query: 197 HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRAN 256 E + ++ V DTP + + S+V+Y E+Y Q + K + + T Y + Sbjct: 4638 GKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYT-TVLETVDYDRTRNLK 4696 Query: 257 ELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQ-----GYPEEYEEHRGKGSF 311 L S Y + + R A I L+ A Y EEYE+ + + Sbjct: 4697 NLYSSNLYKEAWD---RVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTL 4753 Query: 312 PAMITPAYQNAK--KAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVS 369 P + A+ + +L D YR + K K H D + + A+ K VS Sbjct: 4754 PRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHI----VPDMVEMVTAKDSQKKVS 4809 Query: 370 ENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKAD--YKHDIVDYNYPATLT 427 E Y+ + V H KV S++ YK D + I Y + T Sbjct: 4810 EIDYRLRLHEWICHPDLQVND-----HVRKVTDQISDIVYKDDLNWLKGIGCYVWD---T 4861 Query: 428 PSYQTAMKLVPLKD-ANYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKN 484 P A L+D Y+ + K + Y VTDTP VQA + +QLS Y DY + Sbjct: 4862 PEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHS 4921 Query: 485 KLNYTLPQD-VPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELA 543 P L +A KL S YK +T G+ + D K + ++ Sbjct: 4922 VRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSL-RTLPTGYRLPGDTPHFKHIKDTRYMS 4980 Query: 544 SNIKYKEEYEKTK--GKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVN 601 S KYKE YE TK G +G D +H ++ ++SE Y++ + + K + H D Sbjct: 4981 SYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPE 5040 Query: 602 IRHAKKAQTLASDLDYRK---KLHEYTV-LPEDMKTQWAKKAYGLQSELQYKADLAWMKG 657 IR KK Q S+L Y+ K+ + + LP + + + S+++YK DL +KG Sbjct: 5041 IRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKG 5100 Query: 658 VGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL--KFTSVTDSSQMEHAKKSQELQSGVA 715 G + ++ +++ +L S Y + ++ K+ V D+ + ++ + S + Sbjct: 5101 FGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELV 5160 Query: 716 YKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAA 775 Y+A ++ +T D P L+A+ S+ LY ++ + A Sbjct: 5161 YRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPH-HHAGNQTTALKHA 5219 Query: 776 KAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQ 835 K +D+ SE KYK YE+ + K D + + + S+L YK+ F+ TK + Sbjct: 5220 KDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNA---SDLRYKETFQKTKGK 5276 Query: 836 CHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL------PTDMKVEWAKKAYGLQSDN 889 H D + +V+ RK + + YK E++ + L P + + SD Sbjct: 5277 YHTVKDALDIVYHRKVTDDISKIKYK--ENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDV 5334 Query: 890 QYRADVKWMKGMG------------------------------------WVATGSLNVEQ 913 +Y+ D+ W+KG+G +VA +N Sbjct: 5335 KYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPIN-RH 5393 Query: 914 AKKAGELISEKKYR----QHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH 969 K A +L++EKKYR Q D K+ + D P + A+ + Q YR+ E K Sbjct: 5394 FKYATQLMNEKKYRADYEQRKD--KYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK 5451 Query: 970 YTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYK 1029 +T D PE L IS+ YK ++K + GY D + + +SD K Sbjct: 5452 FTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLK 5511 Query: 1030 YKEAFEKMKGQMLGSRSLEDD-ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAAL 1088 YKE +++ K ++E D + + + A + ++++YKK +E +KA + D Sbjct: 5512 YKEVYQRNKSNC----TIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDF 5567 Query: 1089 VHAKKAQTLASNQDYKHPLPQYT----SLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1144 + A K+ S+ +YK S+ +D A + ++S+ Y+ RG Sbjct: 5568 LQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGT 5627 Query: 1145 ACVIPGTLEIEGRKKASELISESKYRQHPHSF----KYTAVTDTPNLLHAKFSNQITNER 1200 +P T +I K S L+SE+KY+ H YT + +T + +H K + ++ Sbjct: 5628 CHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT 5687 Query: 1201 LYKA--AGEDARHEYTMTLGLPEFIRAKTNAANLSDARY-KESWRNL------------- 1244 YK E + Y++ L PE A A SD Y K++ NL Sbjct: 5688 NYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKK 5747 Query: 1245 -----------------RAQG-YKLTIEALP-FQAARASGDIASDFLYRHDFVKERGKLI 1285 R +G + L++ P + A+ + ++S YR +F KE+GK Sbjct: 5748 ATQAAKQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKT- 5806 Query: 1286 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPM----DMVHLVHAKNAQALA 1341 + +D + + L SE++Y+ + + H P+ + + + H N LA Sbjct: 5807 PKYNPKDSQLYKVMKDANNLASEVKYK----ADLKKLHKPVTDMKESLIMNHVLNTSQLA 5862 Query: 1342 SDHDYRTQYHK----FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQM 1397 S + Y+ +Y K + +P++L+ K+A LQS ++YK +G L +P Sbjct: 5863 SSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTY 5922 Query: 1398 ESAKKAGELISETKYRKK-PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESL 1453 +AK++ ++ S +YRK +SIK T + +P L+H K + +E+ YR ES+ Sbjct: 5923 ITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESI 5982 Query: 1454 HR--YTLIPDHPDFTRARLNALHLSDKVYRNSWE-QTRAGSYDFRLDAIP-FQTARASRE 1509 T + D PD RA+ L++K Y+ E + + + + P F AR + + Sbjct: 5983 RGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATD 6042 Query: 1510 IASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSST 1569 IAS +YK++ ++ + SV D P + H V L S +YK+D KS S + + Sbjct: 6043 IASQIKYKQSAEMEKA---NFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVL 6099 Query: 1570 DQPGLLQAKRSQQLASDVHYRQPLPQP-------TCDPEQLGLRHAQKAHQLQSDVKYKS 1622 D P + + + +Q+ S + Y+ L PE L ++ QK S V YK Sbjct: 6100 DTPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNF---SSVLYKE 6156 Query: 1623 DLNLTRGVGWTP 1634 D++ +G TP Sbjct: 6157 DVSPGTAIGKTP 6168 Score = 330 bits (845), Expect = 9e-90 Identities = 380/1615 (23%), Positives = 670/1615 (41%), Gaps = 186/1615 (11%) Query: 157 YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRS 216 Y +D +G G + TP AK A L ++YK + + + V DTP +++ Sbjct: 4844 YKDDLNWLKGIGCY-VWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQA 4902 Query: 217 -KAGAQLQSDVRYTEDYEQQ-RGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRG 274 K+G QL SD Y DY RGK + P T A A +L S Y + G Sbjct: 4903 VKSGKQL-SDAVYHYDYVHSVRGKVA-PTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTG 4960 Query: 275 --MAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDI 332 + G + I Y + Y E YE + G + + ++ + + S+ Sbjct: 4961 YRLPGDTPHFKHIKDTRYMSSYFK-YKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSER 5019 Query: 333 KYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDR 392 YR+ ++K+K H D ++Q + + VSE YK ++ M+G + Sbjct: 5020 LYRELYHKLKDKIH----TTPDTPEIRQVKKTQEAVSELIYKSDFFK-MQGHMISLPYTP 5074 Query: 393 RTLHAMKVGSLASNVAYKADYK------------HDIVDYNYPATLTPSYQTAMKLVPLK 440 + +H VG + S++ YK D + D+V + L +Y K ++ Sbjct: 5075 QVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMR 5134 Query: 441 DANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKA 500 D KY V DTP+ + + LS + YRA +K K +T D P L++A Sbjct: 5135 D----------KYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRA 5184 Query: 501 KTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAM 560 K KL S+ Y E K + +L AK ++ S KYK +YEK K K Sbjct: 5185 KRGQKLQSQYLYVELATKERPHHHAGN-QTTALKHAKDVKDMVSEKKYKIQYEKMKDKYT 5243 Query: 561 GTADSRLLHSLQIAKMS-SEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRK 619 D+ +L + A + S++ YK+ F+++K ++H D ++I + +K S + Y++ Sbjct: 5244 PVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKE 5303 Query: 620 ----KLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAG 675 +L + +P+ + + S+++YK DL W+KG+G + + A+K Sbjct: 5304 NYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNK 5363 Query: 676 QLVSEKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 733 L S+ Y++ + K F V DS H K + +L + Y+A EQ +Y + DE Sbjct: 5364 TLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDE 5423 Query: 734 PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYER 793 P L A+ +S+ Y+ ++E K K F +D+ L S++ YK +Y + Sbjct: 5424 PRHLLAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNK 5482 Query: 794 SRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQH 853 ++ + G + + H ++ S+L+YK+ ++ KS C + D VH+ A+ A Sbjct: 5483 AKPR--GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYK 5540 Query: 854 LATDVGYKTA----EHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSL 909 + T++ YK + H+ P A K+ QSD +Y+ D +++KG T Sbjct: 5541 VNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDK 5600 Query: 910 N-----------------------------------VEQAKKAGELISEKKYRQHPDAL- 933 N + AK L+SE KY+ H Sbjct: 5601 NTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHL 5660 Query: 934 ---KFTSIKDTPEMVQAR-----ISYTQAVDRLYREQGEN----------IKH------- 968 +T++ +T + V + +S T + +E+G++ +KH Sbjct: 5661 AQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKK 5720 Query: 969 --------------HYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALP 1014 HYT AD P++ A A SE Y+ K +G + L + P Sbjct: 5721 QSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRK--EGSHGLSMLGRP 5778 Query: 1015 -FQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFE 1073 + AK + ++ S KY+E F+K KG+ + + A +L S+V YK + Sbjct: 5779 DIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKD-ANNLASEVKYKADLK 5837 Query: 1074 HSKAQFHLPL----DMAALVHAKKAQTLASNQDYKHPLPQ----YTSLAEDLRLSCAKKA 1125 + H P+ + + H LAS+ YK + Y ++ ++L K+A Sbjct: 5838 ----KLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEA 5893 Query: 1126 HKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ-HPHSFK---YTAV 1181 +LQS Y+ RG + T K++ ++ S +YR+ + S K T + Sbjct: 5894 TELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGL 5953 Query: 1182 TDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTL--GLPEFIRAKTNAANLSDARYKE 1239 TP LLH K++ +I +E+ Y+ E++ +T P+ +RAK L++ YK Sbjct: 5954 EVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKR 6013 Query: 1240 SWR-NLRAQGYKLTIEALP-FQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQ 1297 ++ +G P F AR + DIAS Y+ E+ SV D P I Sbjct: 6014 DLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFT---SVVDTPEII 6070 Query: 1298 HCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHA----KNAQALASDHDYRTQYHKF 1353 H +++ L S+ +Y+ A S + + +D + KN L D + K Sbjct: 6071 HAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGKI 6130 Query: 1354 TALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYR 1413 T + + ++ K+ S + YK D+ IG ++P+M K+ + IS KY+ Sbjct: 6131 TVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIG----KTPEMMRVKQTQDHISSVKYK 6186 Query: 1414 KKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNAL 1473 + + T + D P++ K + H + MY+ E+L P+ R + N Sbjct: 6187 EAIG--QGTPIPDLPEVKRVKETQKHISSVMYK----ENLGTGIPTTVTPEIERVKRNQE 6240 Query: 1474 HLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSV 1533 + S +Y+ + + ++ + + ++E S YKE + L + Sbjct: 6241 NFSSVLYKENLGKGIPTPITPEMERV-----KRNQENFSSVLYKENMGKGTPLAV----- 6290 Query: 1534 DDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPL 1593 P M+ + S YK++ K+ + + P + + KR+Q+ S V Y++ L Sbjct: 6291 --TPEMERVKHNQENISSVLYKENVGKATA----TPVTPEMQRVKRNQENISSVLYKENL 6344 Query: 1594 PQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAE 1648 + T P + ++ + S V YK ++ TP ++E A+R E Sbjct: 6345 GKATPTPFTPEMERVKRNQENFSSVLYKENMRKATPTPVTP----EMERAKRNQE 6395 Score = 305 bits (780), Expect = 3e-82 Identities = 387/1603 (24%), Positives = 663/1603 (41%), Gaps = 221/1603 (13%) Query: 141 PEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199 P++VR RK YT+ + R K + TP Y++ ++ S++ Y+ + Sbjct: 5109 PDMVRSRHLRKLWSNYLYTDKARKMRDKYKV-VLDTPEYRKVQELKTHLSELVYRAAGKK 5167 Query: 200 RISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELA 259 + S F++V DTP+LLR+K G +LQS Y E ++R T A + AK ++ Sbjct: 5168 QKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPH-HHAGNQTTALKHAKDVKDMV 5226 Query: 260 SDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAY 319 S+ +Y QY+K D+Y P TP Sbjct: 5227 SEKKYKIQYEK-------------------MKDKYT----------------PVPDTPIL 5251 Query: 320 QNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQN 379 AK+A+ ASD++Y++ F K KG YH++ +D L + + V +S+ KYKENY + Sbjct: 5252 IRAKRAYWNASDLRYKETFQKTKGK--YHTV--KDALDIVYHRKVTDDISKIKYKENYMS 5307 Query: 380 HMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPL 439 + G + + H V S+V YK Sbjct: 5308 QL-GIWRSIPDRPEHFHHRAVTDTVSDVKYK----------------------------- 5337 Query: 440 KDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVK 499 +D + + I Y DTP A+ N S Y+ +E+ K ++ D P Sbjct: 5338 EDLTWLKGIGCYAY----DTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRH 5393 Query: 500 AKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKA 559 K +L +E KY+ +E+ K K + + +D L AK +G+ S IKY++ YEK+K K Sbjct: 5394 FKYATQLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKF 5452 Query: 560 MGTADS-RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPM-DMVNIRHAKKAQTLASDLDY 617 D+ L + ++ K S++ YK + ++K R + + D + H +K + SDL Y Sbjct: 5453 TSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKY 5512 Query: 618 R----KKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKK 673 + + T+ P+ + + AK AY + + L YK K T + QA K Sbjct: 5513 KEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAK 5572 Query: 674 AGQLVSEKNYRQRVDELKFT--SVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISK 731 + S+ Y+ + LK SVTD A ++ ++S + YK E+ V + Sbjct: 5573 SSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYK---EKHVKERGTCH 5629 Query: 732 DEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDY 791 P D+ L AK +L SE KYK+ Sbjct: 5630 AVP---------------------------------DTPQILLAKTVSNLVSENKYKDHV 5656 Query: 792 ERSRGKLIGAKDVQGDSQMS-HSLQMSKLQSELEYKKGF--EDTKSQCHVSLDMVHLVHA 848 ++ + G+ +++ + H +++K S+ YKK F E KS + L+ + HA Sbjct: 5657 KKHLAQ--GSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHA 5714 Query: 849 RKAQHLATDVGY-KTAEH--HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVA 905 + +DV Y K A+ H+T + ++ A +A S+ +YRA + G Sbjct: 5715 MEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSM 5774 Query: 906 TGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYRE--QG 963 G ++E AKKA +L S+ KYR++ D K + K P+ Q + + L E Sbjct: 5775 LGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQL-YKVMKDANNLASEVKYK 5833 Query: 964 ENIKHHYTPTADLPEVLLAK--LNAMNISET-RYKESWSKLRDGGYKLRLDALPFQAAKA 1020 ++K + P D+ E L+ LN ++ + +YK+ + K + G Y D L K Sbjct: 5834 ADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSK-GHYHTIPDNLEQLHLKE 5892 Query: 1021 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHS-KAQF 1079 + E+ S KYKE +EK +G+ + I+ S +QS Y+K +E S K + Sbjct: 5893 ATELQSIVKYKEKYEKERGKPMLDFETPTYITAKES---QQMQSGKEYRKDYEESIKGRN 5949 Query: 1080 HLPLDMA-ALVHAKKAQTLASNQDYKHPLPQ------YTSLAEDLRLSCAKKAHKLQSEN 1132 L++ AL+H K A +AS ++Y+ L + T + + + AK A ++ +E Sbjct: 5950 LTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEK 6009 Query: 1133 LYRSDLNFM---RGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK--YTAVTDTPNL 1187 Y+ DL RG+ + T + + A+++ S+ KY+Q K +T+V DTP + Sbjct: 6010 EYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEI 6069 Query: 1188 LHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQ 1247 +HA+ +++++ YK E + Y L PE R + N N S +Y+ +N + Sbjct: 6070 IHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKG- 6128 Query: 1248 GYKLTI--EALPFQAARASGDIASDFLYRHDFVKERGKLIG--PQSVR------------ 1291 K+T+ + + + S LY+ D G IG P+ +R Sbjct: 6129 --KITVVQDTPEILRVKENQKNFSSVLYKEDV--SPGTAIGKTPEMMRVKQTQDHISSVK 6184 Query: 1292 ------------DDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQA 1339 D P ++ + + S + Y+ + P + K Q Sbjct: 6185 YKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTP----EIERVKRNQE 6240 Query: 1340 LASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMES 1399 S Y+ K P +M K+ S + YK ++ G G +P+ME Sbjct: 6241 NFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKENM----GKGTPLAVTPEMER 6296 Query: 1400 AKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLI 1459 K E IS Y++ T V +P++ K + + + +Y+ E+L + T Sbjct: 6297 VKHNQENISSVLYKENVGKATATPV--TPEMQRVKRNQENISSVLYK----ENLGKATPT 6350 Query: 1460 PDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEA 1519 P P+ R + N + S +Y+ + + ++ A+ ++E S Y ++ Sbjct: 6351 PFTPEMERVKRNQENFSSVLYKENMRKATPTPVTPEMER-----AKRNQENISSVLYSDS 6405 Query: 1520 FLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKR 1579 F + + Y V D P M+ R S +Y +DF K + F P + K+ Sbjct: 6406 FRKQIQGKAAY--VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKK 6463 Query: 1580 SQQLASDVHYR------QPLPQPTCDPEQ---LGLRHAQKAHQLQSDVKYKSDLNLTRGV 1630 + Q SD++YR + Q D +Q GLR + D D +R + Sbjct: 6464 NMQDFSDINYRGIQRKVVEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSL 6523 Query: 1631 GWTPPGSYKVEMARRAAELA-NARGLGLQGAYRGAEAVEAGDH 1672 V+ RR+ E + +A L + G +E EA DH Sbjct: 6524 -----HMINVQAQRRSREQSRSASALSISGGEEKSEHSEAPDH 6561 >gi|169217576 PREDICTED: similar to nebulin [Homo sapiens] Length = 410 Score = 330 bits (846), Expect = 7e-90 Identities = 167/395 (42%), Positives = 250/395 (63%) Query: 737 LQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRG 796 LQA NA +S KLY+ W + K KG+++R D++ AKA R++ASE KYKE Y + G Sbjct: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 Query: 797 KLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLAT 856 +G + +Q D + ++ +K+QS+ EYKK +E +K + LDM+ +V A+K Q L + Sbjct: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 Query: 857 DVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKK 916 D+ Y+ H +T LP V AKKAY LQSDN Y++D++W+KG+GW+ GS+ V + K Sbjct: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181 Query: 917 AGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADL 976 A L++E+ YR P+ALKFTSI DTPE++QA+I+ Q + LYR E K + AD Sbjct: 182 AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241 Query: 977 PEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEK 1036 P +L +K+NA+ IS RY+++W ++ GY LR DA+ Q AKAS +I SDY YK A+EK Sbjct: 242 PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301 Query: 1037 MKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQT 1096 KG +G RS ++D L + +Q+D YKK + KA+ +P+DM ++ AK+ Q Sbjct: 302 QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361 Query: 1097 LASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSE 1131 LAS+ DY+H L ++ + + A+KA+ LQS+ Sbjct: 362 LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 300 bits (767), Expect = 1e-80 Identities = 157/396 (39%), Positives = 241/396 (60%), Gaps = 4/396 (1%) Query: 497 LVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 556 +++A NA S Y++ W TK KG++++ DA+ + AKAS E+AS KYKE Y K Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 557 GKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLA 612 G MG D + + ++ AK+ S+ EYKK +E+SK + P+DM++I AKK Q L Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 613 SDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAK 672 SD+DYR LH++T LP+ AKKAY LQS+ YK+DL W+KG+GWL EGS+ + + K Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 Query: 673 KAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 732 A L++E+ YR + + LKFTS+ D+ ++ AK + S Y+ E+ + D Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 733 EPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYE 792 PL LQ++ NA +S K Y+ +WE+ K G++LR D++ AKA RD+AS+ YK YE Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 793 RSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQ 852 + +G IG + + D ++ + + K+Q++ YKK + D K++ + +DMV + A++ Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 853 HLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSD 888 LA+DV Y+ HH++ P V A+KAY LQSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 298 bits (764), Expect = 2e-80 Identities = 150/397 (37%), Positives = 247/397 (62%) Query: 979 VLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMK 1038 +L A +NA+ IS Y++ W+ + GY +R DA+ + AKAS EI S+YKYKE + K Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 1039 GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLA 1098 G +G R+L+DD +++A +QSD YKK +E SK + PLDM ++V AKK Q L Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 1099 SNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRK 1158 S+ DY++ L Q+T L + + AKKA+ LQS+NLY+SDL +++G+ + G++E+ K Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 Query: 1159 KASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLG 1218 A L++E YR P + K+T++ DTP ++ AK + +E LY+ A E + + Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 1219 LPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFV 1278 P +++K NA +S+ RY+++W +++ GY L +A+ Q A+AS DIASD+LY+ + Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 1279 KERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQ 1338 K++G IG +S ++DP++ + ++Q++ Y++ +A+ +P+DMV + AK Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 1339 ALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSEL 1375 ALASD DYR H ++ P+ + A+KA+ LQS++ Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 Score = 283 bits (724), Expect = 1e-75 Identities = 146/396 (36%), Positives = 241/396 (60%) Query: 1223 IRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERG 1282 ++A NA +S+ Y++ W + + +GY + +A+ + A+AS +IAS++ Y+ + K+ G Sbjct: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 Query: 1283 KLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALAS 1342 +G ++++DDP+ ++QS+ +Y++ S+ + P+DM+ +V AK Q L S Sbjct: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 Query: 1343 DHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKK 1402 D DYR H++T LP+ + AKKA+ LQS+ YKSDL +KGIGWL S ++ K Sbjct: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181 Query: 1403 AGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDH 1462 A L++E YR KP+++KFT++VD+P+++ AK + + +E +YR+ + + D Sbjct: 182 AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241 Query: 1463 PDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLR 1522 P ++++NAL +S+K Y+ +WE + YD R DAI Q A+ASR+IASD+ YK A+ + Sbjct: 242 PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301 Query: 1523 DRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQ 1582 +G IG RS +DP++ NV ++Q+D YKK + +++ D + AK Q Sbjct: 302 QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361 Query: 1583 LASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDV 1618 LASDV YR L +C P+Q + A+KA+ LQSDV Sbjct: 362 LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 Score = 189 bits (481), Expect = 2e-47 Identities = 133/443 (30%), Positives = 224/443 (50%), Gaps = 55/443 (12%) Query: 213 LLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEM 272 +L++ A S+ Y +D+ + KG + AK + E+AS+ +Y + Y+K++ Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 273 ---RGMAGPAIGAEGILTRECAD-QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHEL 328 G + + A Q + Y + YE+ +G + P + Q AKK L Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQ-AKKCQVL 119 Query: 329 ASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGV 388 SDI YR ++ + LP Q++++ QA+ L S+N YK + + +G+ Sbjct: 120 VSDIDYRNYLHQ------WTCLPDQNDVI--QAKKAYDLQSDNLYKSDLE-----WLKGI 166 Query: 389 G-MDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQS 447 G + ++ M+V + A N+ L + YR Sbjct: 167 GWLPEGSVEVMRVKN-AQNL-------------------------------LNERLYRIK 194 Query: 448 IDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLF 507 + LK++S+ DTP+++QAKINA Q+S YR +EK K N +P D P ++++K NA Sbjct: 195 PEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQI 254 Query: 508 SEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMG----TA 563 S +Y++ WE K G++++ DA+ + AKAS ++AS+ YK YEK KG +G Sbjct: 255 SNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKE 314 Query: 564 DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHE 623 D +L+ + + KM ++ YKK + + K + +P+DMV+I AK+ Q LASD+DYR LH Sbjct: 315 DPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYRHYLHH 374 Query: 624 YTVLPEDMKTQWAKKAYGLQSEL 646 ++ P+ A+KAY LQS++ Sbjct: 375 WSCFPDQNDVIQARKAYDLQSDV 397 Score = 165 bits (418), Expect = 3e-40 Identities = 80/187 (42%), Positives = 119/187 (63%) Query: 1467 RARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGL 1526 +A +NAL +S+K+Y+ W T+ YD R DAI + A+ASREIAS+++YKE + + G Sbjct: 3 QAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH 62 Query: 1527 QIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASD 1586 +G+R++ DDP+ ++ ++QSD EYKK + KS+ ++ D ++QAK+ Q L SD Sbjct: 63 HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSD 122 Query: 1587 VHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRA 1646 + YR L Q TC P+Q + A+KA+ LQSD YKSDL +G+GW P GS +V + A Sbjct: 123 IDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNA 182 Query: 1647 AELANAR 1653 L N R Sbjct: 183 QNLLNER 189 Score = 72.0 bits (175), Expect = 5e-12 Identities = 72/339 (21%), Positives = 133/339 (39%), Gaps = 57/339 (16%) Query: 1304 QLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK-------FTAL 1356 Q+ ++L + + Q + + D + + HAK ++ +AS++ Y+ Y K F L Sbjct: 10 QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69 Query: 1357 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKP 1416 +D K WA A +QS+ YK KGI L + AKK L+S+ YR Sbjct: 70 QDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY- 128 Query: 1417 DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLS 1476 LH++T +PD D +A+ S Sbjct: 129 ------------------------------------LHQWTCLPDQNDVIQAKKAYDLQS 152 Query: 1477 DKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDD 1536 D +Y++ E + + +P + R + E R + + + S+ D Sbjct: 153 DNLYKSDLEWLKGIGW------LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDT 206 Query: 1537 PRMKHFLNVGRLQ-SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQ 1595 P + + +Q S+ Y+ + K ++ + D P +LQ+K + S+ Y+Q Sbjct: 207 PEVIQ-AKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWED 265 Query: 1596 PTCD-----PEQLGLRHAQKAHQLQSDVKYKSDLNLTRG 1629 + +G++HA+ + + SD YK+ +G Sbjct: 266 VKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKG 304 Score = 58.5 bits (140), Expect = 5e-08 Identities = 72/284 (25%), Positives = 128/284 (45%), Gaps = 54/284 (19%) Query: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193 LPD V ++A+K+ + Y D E +G G P R K A L ++ Y Sbjct: 135 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 191 Query: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAK 253 + + +F+++VDTPE++++K A S+ Y +E+++ + PA TP + Sbjct: 192 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA-DTP-LMLQS 247 Query: 254 RANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPA 313 + N L + +QQ ++++ M G + A+ I Sbjct: 248 KINALQISNKRYQQAWEDVK-MTGYDLRADAI---------------------------- 278 Query: 314 MITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSL-PAQDNLVLKQAQSVNKLVSENK 372 Q+AK + ++ASD Y+ + K KG HY A+++ L A +V K+ ++ Sbjct: 279 ----GIQHAKASRDIASDYLYKTAYEKQKG--HYIGCRSAKEDPKLVWAANVLKMQNDRL 332 Query: 373 YKENYQNHMRGRYEGVGMDRRTLHAMKVG-SLASNVAYKADYKH 415 YK+ Y +H + +D ++ A K G +LAS+V DY+H Sbjct: 333 YKKAYNDHK--AKISIPVDMVSISAAKEGQALASDV----DYRH 370 >gi|5453758 nebulette sarcomeric isoform [Homo sapiens] Length = 1014 Score = 194 bits (493), Expect = 6e-49 Identities = 198/822 (24%), Positives = 376/822 (45%), Gaps = 57/822 (6%) Query: 449 DKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFS 508 D++ Y V + + A+ + +S + Y+ +++K+K T D P L K S Sbjct: 26 DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFIS 85 Query: 509 EVKYKEGWEKTKGKGFEMKLDAM--SLLAAKASGELASNIKYKEEYEKTKG---KAMGTA 563 E KYK + ++ A S+ A + + +L S + YK++++ KG A Sbjct: 86 EAKYKGTIKADLSNSLYKRMPATIDSVFAGEVT-QLQSEVAYKQKHDAAKGFSDYAHMKE 144 Query: 564 DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKK--- 620 + H++++ K S + Y+K +++ T + +D +I+ A + + S+ +Y+K Sbjct: 145 PPEVKHAMEVNKHQSNISYRKDVQDTHT-YSAELDRPDIKMATQISKIISNAEYKKGQGI 203 Query: 621 LHEYTVLPEDMKTQWAKKAYGLQSELQYKADL---AWMKGVGWLTEGSLNLEQAKKAGQL 677 +++ + + A +A L S+++YK K + S + Q + A L Sbjct: 204 MNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATL 263 Query: 678 VSEKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPL 735 S Y++ + + + + + ++H K+ ++ SG YK E++ Y D Sbjct: 264 ASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVE 323 Query: 736 FLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERS- 794 L + NA S+ YK +E K K +++ ++ A+K + + SE YKED+E+ Sbjct: 324 HLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEI 383 Query: 795 RGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFED--TKSQCHVSLDMVHLVHARKAQ 852 +G+ + D+ + H ++ L E EYKK E+ ++ +++ + A++A Sbjct: 384 KGR--SSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRAS 441 Query: 853 HLATDVGYK------TAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKW-MKGMGW-V 904 +A++ YK A ++++ AKKA + S+ Y+ D++ +KG G V Sbjct: 442 EMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQV 501 Query: 905 ATGSLNVEQAKKAGELISEKKYRQH-PDALKFTSIK---DTPEMVQARISYTQAVDRLYR 960 +T +L+V++AKKA E+ S+K+Y++ + +K ++ D P++++A+ + R Y+ Sbjct: 502 STDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYK 561 Query: 961 EQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKA 1020 ++ E + +Y+ AD PE+ K NIS YK+ G D+ + K Sbjct: 562 DEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKK-----EVGAGTAVKDSPEIERVKK 616 Query: 1021 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH 1080 + + IS KYKE ++ + ++ D L S++ YK+ ++ KA Sbjct: 617 NQQNISSVKYKE-------EIKHATAISDPPELKRVKENQKNISNLQYKE--QNYKA--- 664 Query: 1081 LPLDMA-ALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN 1139 P+ M + ++ Q S YK L + T++++ L AK+ K S YR L Sbjct: 665 TPVSMTPEIERVRRNQEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQL- 723 Query: 1140 FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK--YTAVTDTPNLLHAK-FSNQI 1196 G A + T E+E KK E IS KY Q K + + DTP + H K N I Sbjct: 724 ---GRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHI 780 Query: 1197 TNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYK 1238 + + ++ + +T + P R + N +SDA YK Sbjct: 781 SMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822 Score = 189 bits (480), Expect = 2e-47 Identities = 218/820 (26%), Positives = 354/820 (43%), Gaps = 101/820 (12%) Query: 322 AKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHM 381 A+K EL SDI+Y+++F K K + D+ +L +++ +SE KYK + + Sbjct: 42 ARKCTELISDIRYKEEFKKSKDKCTF----VTDSPMLNHVKNIGAFISEAKYKGTIKADL 97 Query: 382 -RGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIV----DYNYPATLTPSYQTAMKL 436 Y+ + ++ A +V L S VAYK KHD DY + P + AM++ Sbjct: 98 SNSLYKRMPATIDSVFAGEVTQLQSEVAYK--QKHDAAKGFSDYAHMKE-PPEVKHAMEV 154 Query: 437 -VPLKDANYRQSI-DKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDV 494 + +YR+ + D YS+ D P I A Q+S + A+Y+K + V Sbjct: 155 NKHQSNISYRKDVQDTHTYSAELDRPDIKM----ATQISKIISNAEYKKGQGIMNKEPAV 210 Query: 495 ---PQLVKAKTNAKLFSEVKYKEGW--EKTKGKGFEMKLDAMSLLAAKASGELASNIKYK 549 P A +KL S++KYKE + E K L++ S + + LASN+KYK Sbjct: 211 IGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYK 270 Query: 550 EEYEKTKGKAMGTADSRLL-HSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKA 608 ++ + + L H L+ +KM S EYKK FEE+K +H D V H K Sbjct: 271 KDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGN 330 Query: 609 QTLASDLDYRKKLHEYTVLP-----EDMKTQWAKKAYGLQSELQYKADLA---------- 653 L S + Y+++ + P E Q +K+A +QSE YK D Sbjct: 331 AVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLD 390 Query: 654 ----------------------------WMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYR 684 +KG G L L++++AK+A ++ SEK Y+ Sbjct: 391 LDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYK 450 Query: 685 QRVDEL----KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV--HQYTISKDEPLFLQ 738 + ++ + + TD+ +M+HAKK+ E+ S YK E + +S D + Sbjct: 451 KDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQR 510 Query: 739 ARANAANLSEKLYKSSWENQ-KAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGK 797 A+ + S+K YK EN+ K KG ++ +D L AK ++ S+ KYK++ E+ Sbjct: 511 AKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSN 570 Query: 798 LIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATD 857 D ++ + Q S + YKK + + V D + +K Q + Sbjct: 571 YSTIADTPEIQRIKTTQQNI---SAVFYKK---EVGAGTAVK-DSPEIERVKKNQQNISS 623 Query: 858 VGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATG---SLNVEQA 914 V YK H TA+ +++ K+ S+ QY K + AT + +E+ Sbjct: 624 VKYKEEIKHATAISDPPELKRVKENQKNISNLQY-------KEQNYKATPVSMTPEIERV 676 Query: 915 KKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTA 974 ++ E +S KY+ + + T+I D PE+ +A+ + + YR Q T + Sbjct: 677 RRNQEQLSAVKYK--GELQRGTAISDPPELKRAKENQKNISNVYYRGQ----LGRATTLS 730 Query: 975 DLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAF 1034 PE+ K N NIS +Y + +++ G L LD + K + IS KY E F Sbjct: 731 VTPEMERVKKNQENISSVKYTQDHKQMK-GRPSLILDTPAMRHVKEAQNHISMVKYHEDF 789 Query: 1035 EKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEH 1074 EK KG+ G + DD T + SD YK H Sbjct: 790 EKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 827 Score = 187 bits (474), Expect = 1e-46 Identities = 223/888 (25%), Positives = 384/888 (43%), Gaps = 98/888 (11%) Query: 138 LPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGH 197 +P E ++ + +GEE E+ +Q K P + + + A+K +L S + YK Sbjct: 3 VPVFEDIKDETEEEKIGEEENEE-DQVFYK---PVIEDLSMELARKCTELISDIRYKEEF 58 Query: 198 DERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSF---PAMITPAYQIAKR 254 + + + V D+P L K S+ +Y + + PA I + A Sbjct: 59 KKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVF--AGE 116 Query: 255 ANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAM 314 +L S+V Y Q++ A+G Y E Sbjct: 117 VTQLQSEVAYKQKHD-----------AAKGF----------SDYAHMKE----------- 144 Query: 315 ITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ-DNLVLKQAQSVNKLVSENKY 373 P ++A + ++ S+I YR+D H+ A+ D +K A ++K++S +Y Sbjct: 145 -PPEVKHAMEVNKHQSNISYRKDVQDT------HTYSAELDRPDIKMATQISKIISNAEY 197 Query: 374 KENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVD--YNYPATLTPSY- 430 K+ Q M +G HA++ L+S + YK + +++ D ++Y + S+ Sbjct: 198 KKG-QGIMNKEPAVIGRPDFE-HAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFR 255 Query: 431 QTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIV---QAKINAQQLSHVNYRADYEKNKLN 487 Q + + Y++ I + + V+D P ++ ++ LS Y+ +E+NK Sbjct: 256 QNQLAATLASNVKYKKDIQNM-HDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGM 314 Query: 488 YTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIK 547 Y D + + K NA L S+VKYKE +EK KGK ++ S A+K + ++ S Sbjct: 315 YHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKV 374 Query: 548 YKEEYEK-TKGKAMGTADS--RLLHSLQIAKMSSEVEYKKGFE-ESKTR-FHLPMDMVNI 602 YKE++EK KG++ D LH I + E EYKK E E K + L ++++I Sbjct: 375 YKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDI 434 Query: 603 RHAKKAQTLASDLDYRKKLHE------YTVLPEDMKTQWAKKAYGLQSELQYKADL-AWM 655 + AK+A +AS+ +Y+K L + ++ Q AKKA + SE YK DL + Sbjct: 435 QRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEI 494 Query: 656 KGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVD-ELKFTSV---TDSSQMEHAKKSQEL 710 KG G ++ +L++++AKKA ++ S+K Y++ ++ E+K + D + AK++ E+ Sbjct: 495 KGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEI 554 Query: 711 QSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSL 770 S YK E+ + Y+ D P + + N+S YK + G ++ DS Sbjct: 555 YSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYK----KEVGAGTAVK-DSP 609 Query: 771 TFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFE 830 K + S VKYKE+ + A + ++ + K S L+YK E Sbjct: 610 EIERVKKNQQNISSVKYKEEIKH-------ATAISDPPELKRVKENQKNISNLQYK---E 659 Query: 831 DTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQ 890 VS+ + R+ Q + V YK TA+ +++ AK+ S+ Sbjct: 660 QNYKATPVSM-TPEIERVRRNQEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVY 718 Query: 891 YRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKF--TSIKDTPEMVQAR 948 YR + G + + +E+ KK E IS KY Q +K + I DTP M + Sbjct: 719 YRGQL----GRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVK 774 Query: 949 ISYTQAVDRLYREQGENIK-HHYTPTADLPEVLLAKLNAMNISETRYK 995 + Y E E K +TP D P + N +S+ YK Sbjct: 775 EAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822 Score = 176 bits (447), Expect = 1e-43 Identities = 204/817 (24%), Positives = 349/817 (42%), Gaps = 78/817 (9%) Query: 688 DELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLS 747 D++ + V + ME A+K EL S + YK ++S + T D P+ + A +S Sbjct: 26 DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFIS 85 Query: 748 EKLYKSSWENQKAKGFELRLDS-LTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQG 806 E YK + + + R+ + + + A L SEV YK+ ++ ++G ++ Sbjct: 86 EAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG-FSDYAHMKE 144 Query: 807 DSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHH 866 ++ H+++++K QS + Y+K +DT + LD + A + + ++ YK + Sbjct: 145 PPEVKHAMEVNKHQSNISYRKDVQDTHTYS-AELDRPDIKMATQISKIISNAEYKKGQGI 203 Query: 867 FTALPT-------DMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGE 919 P + VE +K + ++ ++ ++K K + S + Q + A Sbjct: 204 MNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHH-YNPLESASFRQNQLAAT 262 Query: 920 LISEKKYRQHPDALKFTSIKDTPEMV---QARISYTQAVDRLYREQGENIKHHYTPTADL 976 L S KY++ + + D P ++ + R Y++ E K Y AD Sbjct: 263 LASNVKYKKDIQNMH-DPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADA 321 Query: 977 PEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEK 1036 E L K NA+ S+ +YKE + K + ++ +QA+K + ++ S+ YKE FEK Sbjct: 322 VEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEK 381 Query: 1037 -MKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAAL--VHAKK 1093 +KG+ S L+ H Y T+L + YKK E+ + L+ L AK+ Sbjct: 382 EIKGR--SSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKR 439 Query: 1094 AQTLASNQDYKHPLPQYT------SLAEDLRLSCAKKAHKLQSENLYRSDLNF-MRGVAC 1146 A +AS ++YK L + + L + AKKA ++ SE Y+ DL ++G Sbjct: 440 ASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGM 499 Query: 1147 -VIPGTLEIEGRKKASELISESKYRQH-PHSFKYTAVT---DTPNLLHAKFSNQITNERL 1201 V TL+++ KKASE+ S+ +Y++ + K + D P++L AK +++I ++R Sbjct: 500 QVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRK 559 Query: 1202 YKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALP-FQA 1260 YK E Y+ PE R KT N+S YK+ G ++ P + Sbjct: 560 YKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKE------VGAGTAVKDSPEIER 613 Query: 1261 ARASGDIASDFLYRHDF--------------VKERGKLIGPQSVRDD----------PRI 1296 + + S Y+ + VKE K I ++ P I Sbjct: 614 VKKNQQNISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEI 673 Query: 1297 QHCRRMGQLQSELQYR----RGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK 1352 + RR + S ++Y+ RG S D L AK Q S+ YR Q + Sbjct: 674 ERVRRNQEQLSAVKYKGELQRGTAIS--------DPPELKRAKENQKNISNVYYRGQLGR 725 Query: 1353 FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKY 1412 T L +M KK S ++Y D MKG L L +P M K+A IS KY Sbjct: 726 ATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKY 785 Query: 1413 RKKPDSIK---FTTVVDSPDLVHAKNSYMHCNERMYR 1446 + + K FT VVD P + + ++ Y+ Sbjct: 786 HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822 Score = 162 bits (409), Expect = 3e-39 Identities = 150/566 (26%), Positives = 254/566 (44%), Gaps = 43/566 (7%) Query: 183 KANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFP 242 KA+++ S EYK+ +E + D E L K A LQS V+Y E+YE+ +GK Sbjct: 294 KASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLE 353 Query: 243 AMITPAYQIAKRANELASDVRYHQQYQKEMRGMAG------PAIGAEGILTRECADQYGQ 296 + TP+YQ +K A ++ S+ Y + ++KE++G + P +T + + Sbjct: 354 FVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLRE---K 410 Query: 297 GYPEEYE-EHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNK-MKGAAHYHSLPAQD 354 Y ++ E E +GKG Q AK+A E+AS+ +Y++D +KG D Sbjct: 411 EYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKG---MQAGTD 467 Query: 355 NLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTL-HAMKVGSLASNVAYKADY 413 L ++ A+ ++ SE YK + + ++G+ V D + A K +AS YK D Sbjct: 468 TLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDL 527 Query: 414 KHDIVDYNYPATL-TPSYQTAMKLVPL-KDANYRQSIDKL--KYSSVTDTPQIVQAKINA 469 +++I ++ P A + + Y+ +K+ YS++ DTP+I + K Sbjct: 528 ENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQ 587 Query: 470 QQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLD 529 Q +S V Y+ + T +D P++ + K N + S VKYKE + K D Sbjct: 588 QNISAVFYKKEVGAG----TAVKDSPEIERVKKNQQNISSVKYKE-----EIKHATAISD 638 Query: 530 AMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEES 589 L K + + SN++YKE+ K +M R+ + + S V+YK + Sbjct: 639 PPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRN---QEQLSAVKYKGELQ-- 693 Query: 590 KTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYK 649 R D ++ AK+ Q S++ YR +L T L + + KK S ++Y Sbjct: 694 --RGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYT 751 Query: 650 ADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELK---FTSVTDSSQMEHAKK 706 D MKG L + + K+A +S Y + ++ K FT V D E +K Sbjct: 752 QDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRK 811 Query: 707 SQELQSGVAYKAGNEQSVHQYTISKD 732 + ++ S AYK VH + + D Sbjct: 812 NTQVVSDAAYK-----GVHPHIVEMD 832 Score = 160 bits (406), Expect = 7e-39 Identities = 195/804 (24%), Positives = 338/804 (42%), Gaps = 82/804 (10%) Query: 873 DMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDA 932 D+ +E A+K L SD +Y+ + K K T S + K G ISE KY+ A Sbjct: 36 DLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKA 95 Query: 933 -LKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH-------YTPTADLPEVLLAKL 984 L + K P + + + V +L E KH Y + PEV Sbjct: 96 DLSNSLYKRMPATIDS--VFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVK---- 149 Query: 985 NAMNISETRYKESWSK-LRDGG-YKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQML 1042 +AM +++ + S+ K ++D Y LD + A +IIS+ +YK K +G M Sbjct: 150 HAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYK----KGQGIMN 205 Query: 1043 GSRSLEDDISLAHSVYATSLQSDVNYKKGFEHS---KAQFHLPLDMAALVHAKKAQTLAS 1099 ++ H+V A+ L S + YK+ F++ K + PL+ A+ + A TLAS Sbjct: 206 KEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLAS 265 Query: 1100 NQDYKHPLPQYTSLAEDLR----LSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIE 1155 N YK + DL L KA K+ S Y+ +G+ +E Sbjct: 266 NVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHL 325 Query: 1156 GRKKASELISESKYRQHPHSFKYTAV---TDTPNLLHAKFSNQITNERLYKAAGEDARHE 1212 K + L S+ KY++ K + +TP+ +K + ++ +E++YK ED E Sbjct: 326 HHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYK---EDFEKE 382 Query: 1213 YTMTLGL-----PEFIRAKTNAANLSDARYKESWRN-LRAQGYKLTIEALPFQAARASGD 1266 L PEF+ K L + YK+ N ++ +G +L E L Q A+ + + Sbjct: 383 IKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASE 442 Query: 1267 IASDFLYRHDFVKE-RGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSS--QAQFH 1323 +AS+ Y+ D +GK G Q+ D +QH ++ ++ SE Y+R + Sbjct: 443 MASEKEYKKDLESIIKGK--GMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQ 500 Query: 1324 LPMDMVHLVHAKNAQALASDHDYRTQYHKFTA---------LPEDLKMAWAKKAHALQSE 1374 + D + + AK A +AS Y+ +P+ L+ AK+ + S+ Sbjct: 501 VSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILR---AKRTSEIYSQ 557 Query: 1375 LRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAK 1434 +YK + M +P+++ K + IS Y+K+ + T V DSP++ K Sbjct: 558 RKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEVGA--GTAVKDSPEIERVK 615 Query: 1435 NSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDF 1494 + + + Y+ E + T I D P+ R + N ++S+ Y+ + S Sbjct: 616 KNQQNISSVKYK----EEIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTP 671 Query: 1495 RLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1554 ++ + R ++E S +YK R ++ D P +K + S+ Y Sbjct: 672 EIERV-----RRNQEQLSAVKYKGELQRGT-------AISDPPELKRAKENQKNISNVYY 719 Query: 1555 KKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQL----GLRHAQK 1610 + ++ + + P + + K++Q+ S V Y Q Q P + +RH ++ Sbjct: 720 RGQLGRATTL----SVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKE 775 Query: 1611 AHQLQSDVKYKSDLNLTRGVGWTP 1634 A S VKY D T+G G+TP Sbjct: 776 AQNHISMVKYHEDFEKTKGRGFTP 799 Score = 142 bits (358), Expect = 3e-33 Identities = 170/740 (22%), Positives = 310/740 (41%), Gaps = 83/740 (11%) Query: 956 DRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPF 1015 +++ E+ E + Y P + + LA+ IS+ RYKE + K +D D+ Sbjct: 16 EKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDK-CTFVTDSPML 74 Query: 1016 QAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHS 1075 K G IS+ KYK + L R + I + T LQS+V YK+ + + Sbjct: 75 NHVKNIGAFISEAKYKGTIKADLSNSLYKR-MPATIDSVFAGEVTQLQSEVAYKQKHDAA 133 Query: 1076 K--AQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLR---LSCAKKAHKLQS 1130 K + + + + HA + SN Y+ + + + +L + A + K+ S Sbjct: 134 KGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIIS 193 Query: 1131 ENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ----------------HPH 1174 Y+ M VI G + E +AS+L S+ KY++ Sbjct: 194 NAEYKKGQGIMNKEPAVI-GRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESA 252 Query: 1175 SFK---------------------YTAVTDTPNLL---HAKFSNQITNERLYKAAGEDAR 1210 SF+ + V+D PNLL H ++++ + R YK E+ + Sbjct: 253 SFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENK 312 Query: 1211 HEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASD 1270 Y E + K NA S +YKE + + + +E +QA++ + + S+ Sbjct: 313 GMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSE 372 Query: 1271 FLYRHDFVKERGKLIGPQSVRDD--PRIQHCRRMGQLQSELQYRRGATS--SQAQFHLPM 1326 +Y+ DF KE + G S+ D P H + + L E +Y++ + L Sbjct: 373 KVYKEDFEKE---IKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNS 429 Query: 1327 DMVHLVHAKNAQALASDHDYRTQYHK------FTALPEDLKMAWAKKAHALQSELRYKSD 1380 +++ + AK A +AS+ +Y+ A + L+M AKKA + SE YK D Sbjct: 430 EVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRD 489 Query: 1381 L-IGMKGIGW-LALRSPQMESAKKAGELISETKYRKK-PDSIK---FTTVVDSPDLVHAK 1434 L +KG G ++ + ++ AKKA E+ S+ +Y+K + IK +D PD++ AK Sbjct: 490 LETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAK 549 Query: 1435 NSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDF 1494 + ++R Y+ + L Y+ I D P+ R + ++S Y+ G+ Sbjct: 550 RTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKK-----EVGAGTA 604 Query: 1495 RLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1554 D+ + + +++ S +YKE ++ D P +K + S+ +Y Sbjct: 605 VKDSPEIERVKKNQQNISSVKYKEEIKH-------ATAISDPPELKRVKENQKNISNLQY 657 Query: 1555 KKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQL 1614 K+ K+ + P + + +R+Q+ S V Y+ L + T + L+ A++ + Sbjct: 658 KEQNYKAT----PVSMTPEIERVRRNQEQLSAVKYKGELQRGTAISDPPELKRAKENQKN 713 Query: 1615 QSDVKYKSDLNLTRGVGWTP 1634 S+V Y+ L + TP Sbjct: 714 ISNVYYRGQLGRATTLSVTP 733 Score = 37.0 bits (84), Expect = 0.16 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 1/61 (1%) Query: 138 LPDPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196 L P + + EA+ + +Y ED+E+ +G+G P + P +R +K Q+ S YK Sbjct: 765 LDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGV 824 Query: 197 H 197 H Sbjct: 825 H 825 >gi|239752495 PREDICTED: similar to nebulin [Homo sapiens] Length = 237 Score = 159 bits (401), Expect = 3e-38 Identities = 77/184 (41%), Positives = 118/184 (64%) Query: 786 KYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHL 845 KYKE Y + G +G + +Q D + ++ +K+QS+ EYKK +E +K + LDM+ + Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 846 VHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVA 905 V A+K Q L +D+ Y+ H +T LP V AKKAY LQSDN Y++D++W+KG+GW+ Sbjct: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143 Query: 906 TGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGEN 965 GS+ V + K A L++E+ YR P+ALKFTSI DTPE++QA+I+ Q + N Sbjct: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFN 203 Query: 966 IKHH 969 ++H+ Sbjct: 204 VRHY 207 Score = 145 bits (365), Expect = 4e-34 Identities = 74/163 (45%), Positives = 106/163 (65%), Gaps = 4/163 (2%) Query: 547 KYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNI 602 KYKE Y K G MG D + + ++ AK+ S+ EYKK +E+SK + P+DM++I Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 603 RHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLT 662 AKK Q L SD+DYR LH++T LP+ AKKAY LQS+ YK+DL W+KG+GWL Sbjct: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143 Query: 663 EGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAK 705 EGS+ + + K A L++E+ YR + + LKFTS+ D+ ++ AK Sbjct: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAK 186 Score = 142 bits (359), Expect = 2e-33 Identities = 69/169 (40%), Positives = 108/169 (63%) Query: 1025 ISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLD 1084 + YKYKE + K G +G R+L+DD +++A +QSD YKK +E SK + PLD Sbjct: 20 VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79 Query: 1085 MAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1144 M ++V AKK Q L S+ DY++ L Q+T L + + AKKA+ LQS+NLY+SDL +++G+ Sbjct: 80 MMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139 Query: 1145 ACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFS 1193 + G++E+ K A L++E YR P + K+T++ DTP ++ AK + Sbjct: 140 GWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKIN 188 Score = 130 bits (327), Expect = 1e-29 Identities = 67/186 (36%), Positives = 115/186 (61%), Gaps = 1/186 (0%) Query: 1271 FLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVH 1330 + Y+ + K+ G +G ++++DDP+ ++QS+ +Y++ S+ + P+DM+ Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 1331 LVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWL 1390 +V AK Q L SD DYR H++T LP+ + AKKA+ LQS+ YKSDL +KGIGWL Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142 Query: 1391 ALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDA 1450 S ++ K A L++E YR KP+++KFT++VD+P+++ AK + + +E + +S D Sbjct: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE-VEKSRDN 201 Query: 1451 ESLHRY 1456 ++ Y Sbjct: 202 FNVRHY 207 Score = 118 bits (296), Expect = 4e-26 Identities = 61/163 (37%), Positives = 92/163 (56%), Gaps = 12/163 (7%) Query: 1491 SYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQS 1550 +YD L +P ++YKE + + G +G+R++ DDP+ ++ ++QS Sbjct: 12 TYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQS 59 Query: 1551 DNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQK 1610 D EYKK + KS+ ++ D ++QAK+ Q L SD+ YR L Q TC P+Q + A+K Sbjct: 60 DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKK 119 Query: 1611 AHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANAR 1653 A+ LQSD YKSDL +G+GW P GS +V + A L N R Sbjct: 120 AYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNER 162 Score = 56.6 bits (135), Expect = 2e-07 Identities = 54/190 (28%), Positives = 90/190 (47%), Gaps = 15/190 (7%) Query: 293 QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPA 352 +Y +GY ++ H G + P A A ++ SD +Y++ + K KG H+ P Sbjct: 24 KYKEGYRKQLGHHMGFRTLQD--DPKSVWAIHAAKIQSDREYKKAYEKSKGI---HNTPL 78 Query: 353 QDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKAD 412 D + + QA+ LVS+ Y+ NY + ++ + + A K L S+ YK+D Sbjct: 79 -DMMSIVQAKKCQVLVSDIDYR-NYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKSD 132 Query: 413 YK--HDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQ 470 + I + + A L L + YR + LK++S+ DTP+++QAKINA Sbjct: 133 LEWLKGIGWLPEGSVEVMRVKNAQNL--LNERLYRIKPEALKFTSIVDTPEVIQAKINAV 190 Query: 471 QLSHVNYRAD 480 Q+S V D Sbjct: 191 QISEVEKSRD 200 Score = 40.4 bits (93), Expect = 0.015 Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 8/132 (6%) Query: 429 SYQTAMKLVP---LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK 485 +Y ++ VP K+ +Q + + ++ D P+ V A A+ S Y+ YEK+K Sbjct: 12 TYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK 71 Query: 486 LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 545 + P D+ +V+AK L S++ Y+ + + D ++ AK + +L S+ Sbjct: 72 GIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSD 126 Query: 546 IKYKEEYEKTKG 557 YK + E KG Sbjct: 127 NLYKSDLEWLKG 138 Score = 39.3 bits (90), Expect = 0.033 Identities = 44/175 (25%), Positives = 69/175 (39%), Gaps = 41/175 (23%) Query: 617 YRKKLHE---YTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKK 673 YRK+L + L +D K+ WA A +QS+ +YK KG+ Sbjct: 29 YRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGI--------------- 73 Query: 674 AGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 733 + D + AKK Q L S + Y+ +HQ+T D+ Sbjct: 74 ------------------HNTPLDMMSIVQAKKCQVLVSDIDYR----NYLHQWTCLPDQ 111 Query: 734 PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYK 788 +QA+ S+ LYKS E K G+ L S+ + K ++L +E Y+ Sbjct: 112 NDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165 Score = 38.9 bits (89), Expect = 0.043 Identities = 55/242 (22%), Positives = 94/242 (38%), Gaps = 45/242 (18%) Query: 1149 PGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGED 1208 P T ++ + S E +Q H + + D P + A + +I ++R YK A E Sbjct: 10 PHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEK 69 Query: 1209 ARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIA 1268 ++ + L + ++AK +SD Y RN Q L + QA +A D+ Sbjct: 70 SKGIHNTPLDMMSIVQAKKCQVLVSDIDY----RNYLHQWTCLPDQNDVIQAKKAY-DLQ 124 Query: 1269 SDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDM 1328 SD LY+ S+L++ +G LP Sbjct: 125 SDNLYK--------------------------------SDLEWLKGIG------WLPEGS 146 Query: 1329 VHLVHAKNAQALASDHDYRTQYH--KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKG 1386 V ++ KNAQ L ++ YR + KFT++ + ++ AK SE+ D ++ Sbjct: 147 VEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRH 206 Query: 1387 IG 1388 G Sbjct: 207 YG 208 Score = 38.1 bits (87), Expect = 0.073 Identities = 42/180 (23%), Positives = 72/180 (40%), Gaps = 39/180 (21%) Query: 368 VSENKYKENYQNHMRGRYEGVGM---DRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPA 424 V KYKE Y+ + G + G D +++ A+ + S+ YK Y+ +N P Sbjct: 20 VPSYKYKEGYRKQL-GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPL 78 Query: 425 TLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYE-- 482 + Q V + D +YR + + ++ + D ++QAK S Y++D E Sbjct: 79 DMMSIVQAKKCQVLVSDIDYRNYLHQ--WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWL 136 Query: 483 -------------------KNKLN------------YTLPQDVPQLVKAKTNAKLFSEVK 511 +N LN +T D P++++AK NA SEV+ Sbjct: 137 KGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196 Score = 37.7 bits (86), Expect = 0.096 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 4/76 (5%) Query: 192 EYKRGHDERISR---FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248 +YK G+ +++ F T+ D P+ + + A++QSD Y + YE+ +G + P + Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 249 YQIAKRANELASDVRY 264 Q AK+ L SD+ Y Sbjct: 84 VQ-AKKCQVLVSDIDY 98 Score = 37.0 bits (84), Expect = 0.16 Identities = 36/149 (24%), Positives = 52/149 (34%), Gaps = 44/149 (29%) Query: 1344 HDYRTQYHK-------FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQ 1396 + Y+ Y K F L +D K WA A +QS+ YK KGI L Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 1397 MESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRY 1456 + AKK L+S+ YR LH++ Sbjct: 83 IVQAKKCQVLVSDIDYRNY-------------------------------------LHQW 105 Query: 1457 TLIPDHPDFTRARLNALHLSDKVYRNSWE 1485 T +PD D +A+ SD +Y++ E Sbjct: 106 TCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134 Score = 35.4 bits (80), Expect = 0.47 Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 9/108 (8%) Query: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193 LPD V ++A+K+ + Y D E +G G P R K A L ++ Y Sbjct: 108 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 164 Query: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSF 241 + + +F+++VDTPE++++K A S+V + D R GS+ Sbjct: 165 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHYGSY 210 Score = 31.2 bits (69), Expect = 8.9 Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 9/119 (7%) Query: 441 DANYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLN-YTLPQDVPQL 497 D Y+++ +K K +++ D IVQAK +S ++YR N L+ +T D + Sbjct: 60 DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-----NYLHQWTCLPDQNDV 114 Query: 498 VKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 556 ++AK L S+ YK E KG G+ + ++ ++ K + L + Y+ + E K Sbjct: 115 IQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK 172 >gi|47087157 nebulette non-muscle isoform [Homo sapiens] Length = 270 Score = 125 bits (313), Expect = 5e-28 Identities = 70/198 (35%), Positives = 103/198 (52%), Gaps = 37/198 (18%) Query: 1 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60 MN Q C+RCG VYP EK++C+D+ WHK CFHCEVCKM L++NN+ ++KKPYC+AH PK Sbjct: 1 MNPQ-CARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPK 59 Query: 61 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120 +FT+V TP NL ++ E S + + D E+ K Sbjct: 60 -QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK------------------------ 94 Query: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQ 179 G G + PE+ R+ ++ + +Y ED+E+ +G+G P + P + Sbjct: 95 -------GRGFSI---VTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTE 144 Query: 180 RAKKANQLASQVEYKRGH 197 R +K Q+ S YK H Sbjct: 145 RVRKNTQVVSDAAYKGVH 162 Score = 70.1 bits (170), Expect = 2e-11 Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 1/125 (0%) Query: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233 TP R K+ ++L SQV+YKR +E R FS V DTPEL R K + S+V+Y ED+E Sbjct: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127 Query: 234 QQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQ 293 + +G+G P + P + ++ ++ SD Y + + P I +L Sbjct: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQS 187 Query: 294 YGQGY 298 + QGY Sbjct: 188 HSQGY 192 Score = 65.9 bits (159), Expect = 3e-10 Identities = 49/154 (31%), Positives = 75/154 (48%), Gaps = 10/154 (6%) Query: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263 F+TV DTPE LR K ++LQS V+Y D+E+ +G+G TP Q KR E S+V+ Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 264 YHQQYQK-EMRGMA----GPAIGAEGILTRECADQYGQG-YPEEYEEHRGKGSFPAMITP 317 YH+ ++K + RG P T+ +D +G +P E R G A + P Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLP 181 Query: 318 -AYQNAKKAHELASDIKYRQDFNKMKGAAHYHSL 350 AYQ ++H ++ + M+ H +L Sbjct: 182 GAYQ---QSHSQGYGYMHQTSVSSMRSMQHSPNL 212 Score = 65.5 bits (158), Expect = 4e-10 Identities = 35/91 (38%), Positives = 54/91 (59%), Gaps = 9/91 (9%) Query: 476 NYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMK 527 NY+ YEK K ++T D P+ ++ K ++L S+VKYK +E++KG+GF + Sbjct: 43 NYKG-YEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIV 101 Query: 528 LDAMSLLAAKASGELASNIKYKEEYEKTKGK 558 D L K + E SN+KY E++EKTKG+ Sbjct: 102 TDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132 Score = 62.4 bits (150), Expect = 4e-09 Identities = 32/101 (31%), Positives = 58/101 (57%), Gaps = 1/101 (0%) Query: 450 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 508 K +++V DTP+ ++ K ++ S V Y+ D+E++K +++ D P+L + K + S Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 509 EVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYK 549 VKY E +EKTKG+GF +D + + ++ S+ YK Sbjct: 119 NVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 50.8 bits (120), Expect = 1e-05 Identities = 35/108 (32%), Positives = 49/108 (45%), Gaps = 2/108 (1%) Query: 967 KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1026 K +T AD PE L K + S+ +YK + + + G+ + D Q K + E IS Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 1027 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEH 1074 + KY E FEK KG+ G + DD T + SD YK H Sbjct: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 164 Score = 47.0 bits (110), Expect = 2e-04 Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 12/163 (7%) Query: 663 EGSLNLEQAKKAGQLVSEKNYRQR------VDELKFTSVTDSSQMEHAKKSQELQSGVAY 716 +G + E K A + + K Y ++ + FT+V D+ + K+ ELQS V Y Sbjct: 27 KGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKY 86 Query: 717 KAGNEQSVHQ-YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAA 775 K E+S + ++I D P + + +S Y +E K +GF +D Sbjct: 87 KRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERV 146 Query: 776 KAKRDLASEVKYKEDYER-----SRGKLIGAKDVQGDSQMSHS 813 + + S+ YK + R +I A + G Q SHS Sbjct: 147 RKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQSHS 189 Score = 46.2 bits (108), Expect = 3e-04 Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 7/117 (5%) Query: 141 PEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199 PE +R+ + + + +Y D+E+ +G+G TP QR K+ + S V+Y ++ Sbjct: 69 PENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEK 128 Query: 200 RISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDY----EQQRGKGSFPAMITP-AYQ 250 R F+ VVD P R + Q+ SD Y + E R G A + P AYQ Sbjct: 129 TKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQ 185 Score = 45.8 bits (107), Expect = 4e-04 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 2/103 (1%) Query: 1210 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1269 + +T PE +R K + S +YK + + +G+ + + Q + + + S Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 1270 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYR 1312 + Y DF K +G+ P V DDP + R+ Q+ S+ Y+ Sbjct: 119 NVKYHEDFEKTKGRGFTP--VVDDPVTERVRKNTQVVSDAAYK 159 Score = 45.4 bits (106), Expect = 5e-04 Identities = 39/165 (23%), Positives = 73/165 (44%), Gaps = 32/165 (19%) Query: 572 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 631 ++ KM+ + KG+E+ N + K++ T +D PE++ Sbjct: 33 EVCKMALNMNNYKGYEKKP--------YCNAHYPKQSFTTVADT------------PENL 72 Query: 632 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 690 + K+ LQS+++YK D KG G+ + + L++ K+ + +S Y + ++ Sbjct: 73 RL---KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKT 129 Query: 691 K---FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 732 K FT V D E +K+ ++ S AYK VH + + D Sbjct: 130 KGRGFTPVVDDPVTERVRKNTQVVSDAAYK-----GVHPHIVEMD 169 Score = 44.3 bits (103), Expect = 0.001 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 2/100 (2%) Query: 727 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 786 +T D P L+ + + S+ YK +E K +GF + D+ K ++ S VK Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 787 YKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYK 826 Y ED+E+++G+ G V D + +++ S+ YK Sbjct: 122 YHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 43.5 bits (101), Expect = 0.002 Identities = 28/132 (21%), Positives = 57/132 (43%), Gaps = 7/132 (5%) Query: 1150 GTLEIEGRKKASELISESKYRQHPH------SFKYTAVTDTPNLLHAKFSNQITNERLYK 1203 G E K A + + Y + P+ +T V DTP L K +++ ++ YK Sbjct: 28 GCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYK 87 Query: 1204 AAGEDAR-HEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAAR 1262 E+++ +++ PE R K +S+ +Y E + + +G+ ++ + R Sbjct: 88 RDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVR 147 Query: 1263 ASGDIASDFLYR 1274 + + SD Y+ Sbjct: 148 KNTQVVSDAAYK 159 Score = 43.5 bits (101), Expect = 0.002 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%) Query: 1357 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1415 PE+L++ K+ LQS+++YK D KG G+ + +P+++ K+ E IS KY + Sbjct: 69 PENLRL---KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125 Query: 1416 PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYR 1446 + K FT VVD P + + ++ Y+ Sbjct: 126 FEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 42.7 bits (99), Expect = 0.003 Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 6/109 (5%) Query: 522 KGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMG--TADSRLLHSLQIAKMSSE 579 + F D L K EL S +KYK ++E++KG+ T L + + S Sbjct: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISN 119 Query: 580 VEYKKGFEESKTRFHLPM--DMVNIRHAKKAQTLASDLDYRKKLHEYTV 626 V+Y + FE++K R P+ D V R K Q + SD Y K +H + V Sbjct: 120 VKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQ-VVSDAAY-KGVHPHIV 166 Score = 42.4 bits (98), Expect = 0.004 Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 7/132 (5%) Query: 907 GSLNVEQAKKAGELISEKKYRQHP------DALKFTSIKDTPEMVQARI-SYTQAVDRLY 959 G + E K A + + K Y + P FT++ DTPE ++ + S Q+ + Sbjct: 28 GCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYK 87 Query: 960 REQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAK 1019 R+ E+ ++ D PE+ K IS +Y E + K + G+ +D + + Sbjct: 88 RDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVR 147 Query: 1020 ASGEIISDYKYK 1031 + +++SD YK Sbjct: 148 KNTQVVSDAAYK 159 Score = 42.4 bits (98), Expect = 0.004 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 25/166 (15%) Query: 572 QIAKMSSEVEYKKGFEESKTR-FHLPMDMVNIRHAKKAQTLASDLDYRKKLHE-----YT 625 Q +++ S+V+YK+ FEESK R F + D ++ K+ Q S++ Y + + +T Sbjct: 76 QQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFT 135 Query: 626 VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVS------ 679 + +D T+ +K + S+ YK + +E ++ G +V+ Sbjct: 136 PVVDDPVTERVRKNTQVVSDAAYKGVHPHI------------VEMDRRPGIIVAPVLPGA 183 Query: 680 -EKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV 724 ++++ Q + TSV+ M+H+ + ++ Y A +E V Sbjct: 184 YQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEV 229 Score = 42.0 bits (97), Expect = 0.005 Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 7/127 (5%) Query: 1398 ESAKKAGELISETKYRKKP------DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAE 1451 E K A + + Y KKP FTTV D+P+ + K ++ Y+ E Sbjct: 33 EVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEE 92 Query: 1452 SLHR-YTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREI 1510 S R ++++ D P+ R + +S+ Y +E+T+ + +D + R + ++ Sbjct: 93 SKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV 152 Query: 1511 ASDFRYK 1517 SD YK Sbjct: 153 VSDAAYK 159 Score = 41.2 bits (95), Expect = 0.009 Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 4/112 (3%) Query: 305 HRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQS 363 H K SF + TP K+ EL S +KY++DF + KG D L++ + Sbjct: 56 HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSI---VTDTPELQRLKR 112 Query: 364 VNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKH 415 + +S KY E+++ + V D T K + S+ AYK + H Sbjct: 113 TQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 164 Score = 41.2 bits (95), Expect = 0.009 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 3/111 (2%) Query: 761 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 820 + F D+ L K + +L S+VKYK D+E S+G+ G V ++ + + Sbjct: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQI 117 Query: 821 SELEYKKGFEDTKSQCHVS-LDMVHLVHARKAQHLATDVGYKTAEHHFTAL 870 S ++Y + FE TK + +D RK + +D YK H + Sbjct: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEM 168 Score = 40.8 bits (94), Expect = 0.011 Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 18/126 (14%) Query: 1530 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1588 + +V D P LQS +YK+DF +S+ + F TD P L + KR+Q+ S+V Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 1589 YRQPLPQ-------PTCDPEQLGLRHAQKAHQLQSDVKYKS------DLNLTRGVGWTP- 1634 Y + + P D +K Q+ SD YK +++ G+ P Sbjct: 122 YHEDFEKTKGRGFTPVVDDPV--TERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPV 179 Query: 1635 -PGSYK 1639 PG+Y+ Sbjct: 180 LPGAYQ 185 Score = 37.4 bits (85), Expect = 0.12 Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%) Query: 1509 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHS 1567 E+ S +YK F +G G+ V D P ++ S+ +Y +DF K++ + F Sbjct: 79 ELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTP 136 Query: 1568 STDQPGLLQAKRSQQLASDVHYR 1590 D P + +++ Q+ SD Y+ Sbjct: 137 VVDDPVTERVRKNTQVVSDAAYK 159 Score = 33.9 bits (76), Expect = 1.4 Identities = 36/160 (22%), Positives = 63/160 (39%), Gaps = 21/160 (13%) Query: 1060 TSLQSDVNYKKGFEHSKAQ-FHLPLDMAALVHAKKAQTLASNQDYKHPLPQ-----YTSL 1113 + LQS V YK+ FE SK + F + D L K+ Q SN Y + +T + Sbjct: 78 SELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPV 137 Query: 1114 AEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKK--ASELISESKYRQ 1171 +D +K ++ S+ Y+ V P +E++ R + ++ + + Sbjct: 138 VDDPVTERVRKNTQVVSDAAYKG----------VHPHIVEMDRRPGIIVAPVLPGAYQQS 187 Query: 1172 HPHSFKYTAVTDTPNLLHAKFSNQITNERL---YKAAGED 1208 H + Y T ++ + S + R Y A ED Sbjct: 188 HSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDED 227 Score = 32.7 bits (73), Expect = 3.1 Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 6/96 (6%) Query: 1289 SVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQ-FHLPMDMVHLVHAKNAQALASDHDYR 1347 +V D P ++ +LQS+++Y+R S+ + F + D L K Q S+ Y Sbjct: 64 TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123 Query: 1348 TQYHK-----FTALPEDLKMAWAKKAHALQSELRYK 1378 + K FT + +D +K + S+ YK Sbjct: 124 EDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 >gi|5453710 LIM and SH3 protein 1 [Homo sapiens] Length = 261 Score = 105 bits (263), Expect = 3e-22 Identities = 46/91 (50%), Positives = 64/91 (70%), Gaps = 1/91 (1%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFT 65 C+RCG VYP EK++C+D+ WHKACFHCE CKM L++ N+ ++KKPYC+AH PK +FT Sbjct: 5 CARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPK-QSFT 63 Query: 66 SVYHTPLNLNVRTFPEAISGIHDQEDGEQCK 96 V TP NL ++ E S + +E+ E+ K Sbjct: 64 MVADTPENLRLKQQSELQSQVRYKEEFEKNK 94 Score = 70.1 bits (170), Expect = 2e-11 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 7/126 (5%) Query: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263 F+ V DTPE LR K ++LQS VRY E++E+ +GKG TP Q K+ + S+++ Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 264 YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYP---EEYEEHRGKGSFPAMITPAYQ 320 YH++++K G + G EG+ Q G Y E+ + H S P P Q Sbjct: 122 YHEEFEKSRMGPS----GGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQ 177 Query: 321 NAKKAH 326 +++ Sbjct: 178 PVAQSY 183 Score = 64.3 bits (155), Expect = 1e-09 Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 9/93 (9%) Query: 472 LSHVNYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKG 523 L+ NY+ YEK K ++T+ D P+ ++ K ++L S+V+YKE +EK KGKG Sbjct: 39 LNMKNYKG-YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG 97 Query: 524 FEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 556 F + D L K + + SNIKY EE+EK++ Sbjct: 98 FSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 51.2 bits (121), Expect = 8e-06 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 9/140 (6%) Query: 967 KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1026 K +T AD PE L K + S+ RYKE + K + G+ + D Q K + + IS Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 1027 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMA 1086 + KY E FEK + G +E + Q +Y++ E + H+P Sbjct: 119 NIKYHEEFEKSRMGPSGGEGMEPE--------RRDSQDGSSYRRPLEQQQPH-HIPTSAP 169 Query: 1087 ALVHAKKAQTLASNQDYKHP 1106 ++ S YK P Sbjct: 170 VYQQPQQQPVAQSYGGYKEP 189 Score = 48.5 bits (114), Expect = 5e-05 Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 6/82 (7%) Query: 450 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 508 K ++ V DTP+ ++ K ++ S V Y+ ++EKNK +++ D P+L + K S Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 509 EVKYKEGWEKTK-----GKGFE 525 +KY E +EK++ G+G E Sbjct: 119 NIKYHEEFEKSRMGPSGGEGME 140 Score = 46.2 bits (108), Expect = 3e-04 Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 1/63 (1%) Query: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233 TP R K+ ++L SQV YK ++ + FS V DTPEL R K S+++Y E++E Sbjct: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 Query: 234 QQR 236 + R Sbjct: 128 KSR 130 Score = 43.5 bits (101), Expect = 0.002 Identities = 22/69 (31%), Positives = 36/69 (52%) Query: 727 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 786 +T+ D P L+ + + S+ YK +E K KGF + D+ K +D S +K Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 787 YKEDYERSR 795 Y E++E+SR Sbjct: 122 YHEEFEKSR 130 Score = 43.1 bits (100), Expect = 0.002 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%) Query: 505 KLFSEVKYKEGWEKTK-------GKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG 557 K+ +K +G+EK + F M D L K EL S ++YKEE+EK KG Sbjct: 36 KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95 Query: 558 KAMG-TADSRLLHSLQIAK-MSSEVEYKKGFEESK 590 K AD+ L ++ + S ++Y + FE+S+ Sbjct: 96 KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 41.2 bits (95), Expect = 0.009 Identities = 18/45 (40%), Positives = 27/45 (60%) Query: 298 YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMK 342 Y EE+E+++GKG TP Q KK + S+IKY ++F K + Sbjct: 86 YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 40.8 bits (94), Expect = 0.011 Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 9/116 (7%) Query: 1210 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1269 + +TM PE +R K + S RYKE + + +G+ + + Q + + D S Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 1270 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLP 1325 + Y +F K R G + + + R Q YRR Q H+P Sbjct: 119 NIKYHEEFEKSRMGPSGGEGMEPERR--------DSQDGSSYRR-PLEQQQPHHIP 165 Score = 37.7 bits (86), Expect = 0.096 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 4/88 (4%) Query: 305 HRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQS 363 H K SF + TP K+ EL S ++Y+++F K KG S+ A D L++ + Sbjct: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG--FSVVA-DTPELQRIKK 112 Query: 364 VNKLVSENKYKENYQNHMRGRYEGVGMD 391 +S KY E ++ G G GM+ Sbjct: 113 TQDQISNIKYHEEFEKSRMGPSGGEGME 140 Score = 36.6 bits (83), Expect = 0.21 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%) Query: 1509 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1568 E+ S RYKE F +++G G+ V D P ++ S+ +Y ++F KSR Sbjct: 79 ELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM---GP 133 Query: 1569 TDQPGLLQAKRSQQLASDVHYRQPLPQ 1595 + G+ +R Q S YR+PL Q Sbjct: 134 SGGEGMEPERRDSQDGSS--YRRPLEQ 158 Score = 35.4 bits (80), Expect = 0.47 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 4/60 (6%) Query: 1357 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1415 PE+L++ K+ LQS++RYK + KG G+ + +P+++ KK + IS KY ++ Sbjct: 69 PENLRL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 Score = 34.3 bits (77), Expect = 1.1 Identities = 19/73 (26%), Positives = 39/73 (53%), Gaps = 2/73 (2%) Query: 761 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 820 + F + D+ L K + +L S+V+YKE++E+++GK G V ++ + Sbjct: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQI 117 Query: 821 SELEYKKGFEDTK 833 S ++Y + FE ++ Sbjct: 118 SNIKYHEEFEKSR 130 Score = 33.9 bits (76), Expect = 1.4 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Query: 929 HPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH-YTPTADLPEVLLAKLNAM 987 H FT + DTPE ++ + Y+E+ E K ++ AD PE+ K Sbjct: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115 Query: 988 NISETRYKESWSKLRDG 1004 IS +Y E + K R G Sbjct: 116 QISNIKYHEEFEKSRMG 132 Score = 33.5 bits (75), Expect = 1.8 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query: 1530 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1588 + V D P LQS YK++F K++ + F D P L + K++Q S++ Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 1589 YRQPLPQPTCDP 1600 Y + + P Sbjct: 122 YHEEFEKSRMGP 133 Score = 32.7 bits (73), Expect = 3.1 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%) Query: 141 PEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199 PE +R+ + + + Y E++E+ +GKG TP QR KK S ++Y H+E Sbjct: 69 PENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HEE 125 Score = 31.6 bits (70), Expect = 6.9 Identities = 38/182 (20%), Positives = 77/182 (42%), Gaps = 28/182 (15%) Query: 572 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 631 + KM+ ++ KG+E+ N + K++ T+ +D PE++ Sbjct: 33 ETCKMTLNMKNYKGYEKKP--------YCNAHYPKQSFTMVADT------------PENL 72 Query: 632 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 690 + K+ LQS+++YK + KG G+ + + L++ KK +S Y + ++ Sbjct: 73 RL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129 Query: 691 KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 750 + + ME ++ + Q G +Y+ EQ + I P++ Q + S Sbjct: 130 RM-GPSGGEGMEPERR--DSQDGSSYRRPLEQQ-QPHHIPTSAPVYQQPQQQPVAQSYGG 185 Query: 751 YK 752 YK Sbjct: 186 YK 187 Score = 31.6 bits (70), Expect = 6.9 Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 1178 YTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHE-YTMTLGLPEFIRAKTNAANLSDAR 1236 +T V DTP L K +++ ++ YK E + + +++ PE R K +S+ + Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 1237 YKESWRNLR 1245 Y E + R Sbjct: 122 YHEEFEKSR 130 >gi|116517305 cysteine-rich protein 3 [Homo sapiens] Length = 204 Score = 54.3 bits (129), Expect = 1e-06 Identities = 21/50 (42%), Positives = 28/50 (56%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55 C RC V+ AEK+S + + WH+ C CE C +LS H +PYCH Sbjct: 5 CPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCH 54 Score = 51.2 bits (121), Expect = 8e-06 Identities = 19/50 (38%), Positives = 26/50 (52%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55 C CG VY AEK+ + + WH+ C C+ C L+ + H PYCH Sbjct: 124 CPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCH 173 >gi|4503049 cysteine-rich protein 2 [Homo sapiens] Length = 208 Score = 53.9 bits (128), Expect = 1e-06 Identities = 21/50 (42%), Positives = 27/50 (54%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55 C +C VY AEK+S + + WHK C CE C L+ H KP+CH Sbjct: 5 CPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCH 54 Score = 53.1 bits (126), Expect = 2e-06 Identities = 20/50 (40%), Positives = 27/50 (54%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55 C RC VY AEK++ + + WH+ C CE C L+ H +PYCH Sbjct: 126 CPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCH 175 >gi|189083753 cysteine and glycine-rich protein 3 [Homo sapiens] Length = 194 Score = 50.8 bits (120), Expect = 1e-05 Identities = 22/58 (37%), Positives = 27/58 (46%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61 + C RCG VY AEK+ + WHK CF C +C L N + YC KN Sbjct: 118 EKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAKN 175 Score = 49.7 bits (117), Expect = 2e-05 Identities = 19/49 (38%), Positives = 26/49 (53%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C C VY AE+I C + +HK CFHC C+ L +H+ + YC Sbjct: 10 CGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYC 58 >gi|4502893 cysteine and glycine-rich protein 3 [Homo sapiens] Length = 194 Score = 50.8 bits (120), Expect = 1e-05 Identities = 22/58 (37%), Positives = 27/58 (46%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61 + C RCG VY AEK+ + WHK CF C +C L N + YC KN Sbjct: 118 EKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAKN 175 Score = 49.7 bits (117), Expect = 2e-05 Identities = 19/49 (38%), Positives = 26/49 (53%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C C VY AE+I C + +HK CFHC C+ L +H+ + YC Sbjct: 10 CGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYC 58 >gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens] Length = 77 Score = 50.4 bits (119), Expect = 1e-05 Identities = 18/50 (36%), Positives = 28/50 (56%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55 C +C VY AE+++ + + WH+ C CE C L+ H+ KPYC+ Sbjct: 4 CPKCNKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCN 53 >gi|4503101 cysteine and glycine-rich protein 2 [Homo sapiens] Length = 193 Score = 49.7 bits (117), Expect = 2e-05 Identities = 23/58 (39%), Positives = 27/58 (46%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61 + CSRCG VY AEKI + WHK CF C C L + + YC KN Sbjct: 117 EKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174 Score = 46.6 bits (109), Expect = 2e-04 Identities = 18/49 (36%), Positives = 26/49 (53%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C CG VY AE++ C + +H+ CF C VC+ L H ++ YC Sbjct: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYC 58 >gi|4758086 cysteine and glycine-rich protein 1 isoform 1 [Homo sapiens] Length = 193 Score = 46.6 bits (109), Expect = 2e-04 Identities = 21/56 (37%), Positives = 24/56 (42%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61 C RC VY AEK+ + WHKACF C C L + YC KN Sbjct: 119 CPRCSQAVYAAEKVIGAGKSWHKACFRCAKCGKGLESTTLADKDGEIYCKGCYAKN 174 Score = 43.5 bits (101), Expect = 0.002 Identities = 19/49 (38%), Positives = 25/49 (51%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C C VY AE++ C +HK+CF C VCK L H ++ YC Sbjct: 10 CGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYC 58 >gi|165905591 LIM domain and actin binding 1 isoform c [Homo sapiens] Length = 600 Score = 46.2 bits (108), Expect = 3e-04 Identities = 18/54 (33%), Positives = 27/54 (50%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57 + C C VYP E++ Q++H +CF C C LS+ + S + YC H Sbjct: 229 ETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPH 282 >gi|165905589 LIM domain and actin binding 1 isoform a [Homo sapiens] Length = 760 Score = 46.2 bits (108), Expect = 3e-04 Identities = 18/54 (33%), Positives = 27/54 (50%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57 + C C VYP E++ Q++H +CF C C LS+ + S + YC H Sbjct: 389 ETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPH 442 >gi|7705373 LIM domain and actin binding 1 isoform b [Homo sapiens] Length = 759 Score = 46.2 bits (108), Expect = 3e-04 Identities = 18/54 (33%), Positives = 27/54 (50%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57 + C C VYP E++ Q++H +CF C C LS+ + S + YC H Sbjct: 388 ETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPH 441 >gi|119372315 xin actin-binding repeat containing 2 isoform 2 [Homo sapiens] Length = 938 Score = 45.1 bits (105), Expect = 6e-04 Identities = 20/52 (38%), Positives = 26/52 (50%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57 C C VYP E + Q +HK+CF C C LS+ N+ S + YC H Sbjct: 402 CILCQKTVYPMECLVADKQNFHKSCFRCHHCNSKLSLGNYASLHGQIYCKPH 453 >gi|7662330 actin binding LIM protein family, member 3 [Homo sapiens] Length = 683 Score = 43.9 bits (102), Expect = 0.001 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 11/80 (13%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFT 65 C+ C + + + +D+ WH +CF C+ C ++L+ ++S PYC Sbjct: 151 CAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILT-GEYISKDGVPYCE---------- 199 Query: 66 SVYHTPLNLNVRTFPEAISG 85 S YH + T ISG Sbjct: 200 SDYHAQFGIKCETCDRYISG 219 >gi|221316627 cysteine and glycine-rich protein 1 isoform 2 [Homo sapiens] Length = 140 Score = 43.5 bits (101), Expect = 0.002 Identities = 19/49 (38%), Positives = 25/49 (51%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C C VY AE++ C +HK+CF C VCK L H ++ YC Sbjct: 10 CGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYC 58 >gi|13386490 LIM domain containing 2 [Homo sapiens] Length = 127 Score = 42.4 bits (98), Expect = 0.004 Identities = 17/54 (31%), Positives = 29/54 (53%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57 + C+ C VYP E++ I+H +CF C+ C LS+ ++ + + YC H Sbjct: 38 ETCAACQKTVYPMERLVADKLIFHNSCFCCKHCHTKLSLGSYAALHGEFYCKPH 91 >gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] Length = 280 Score = 42.0 bits (97), Expect = 0.005 Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 24 QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 Q WH CFHC+ C + L+ FV HQ++ YC Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273 Score = 33.5 bits (75), Expect = 1.8 Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 25 IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 +WHK CF C CK ++ +F + YC Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 150 Score = 33.1 bits (74), Expect = 2.4 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C +C + + I+ DQ WH CF C C L+ F + + + YC Sbjct: 162 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209 >gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] Length = 280 Score = 42.0 bits (97), Expect = 0.005 Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 24 QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 Q WH CFHC+ C + L+ FV HQ++ YC Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273 Score = 33.5 bits (75), Expect = 1.8 Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 25 IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 +WHK CF C CK ++ +F + YC Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 150 Score = 33.1 bits (74), Expect = 2.4 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C +C + + I+ DQ WH CF C C L+ F + + + YC Sbjct: 162 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209 >gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] Length = 309 Score = 42.0 bits (97), Expect = 0.005 Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 24 QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 Q WH CFHC+ C + L+ FV HQ++ YC Sbjct: 272 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 302 Score = 33.5 bits (75), Expect = 1.8 Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 25 IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 +WHK CF C CK ++ +F + YC Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 179 Score = 33.1 bits (74), Expect = 2.4 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C +C + + I+ DQ WH CF C C L+ F + + + YC Sbjct: 191 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 238 >gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] Length = 296 Score = 42.0 bits (97), Expect = 0.005 Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 24 QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 Q WH CFHC+ C + L+ FV HQ++ YC Sbjct: 259 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289 Score = 33.5 bits (75), Expect = 1.8 Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 25 IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 +WHK CF C CK ++ +F + YC Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 166 Score = 33.1 bits (74), Expect = 2.4 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C +C + + I+ DQ WH CF C C L+ F + + + YC Sbjct: 178 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 225 >gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] Length = 280 Score = 42.0 bits (97), Expect = 0.005 Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 24 QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 Q WH CFHC+ C + L+ FV HQ++ YC Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273 Score = 33.5 bits (75), Expect = 1.8 Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 25 IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 +WHK CF C CK ++ +F + YC Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 150 Score = 33.1 bits (74), Expect = 2.4 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C +C + + I+ DQ WH CF C C L+ F + + + YC Sbjct: 162 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209 >gi|194272207 actin binding LIM protein family, member 2 isoform 7 [Homo sapiens] Length = 470 Score = 42.0 bits (97), Expect = 0.005 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 3 VQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHA 56 ++ C CG + + + +D+ WH CF C+ C +L+ ++S PYC A Sbjct: 150 LRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNA-EYISKDGLPYCEA 202 >gi|153792514 actin binding LIM protein family, member 2 isoform 6 [Homo sapiens] Length = 521 Score = 42.0 bits (97), Expect = 0.005 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 3 VQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHA 56 ++ C CG + + + +D+ WH CF C+ C +L+ ++S PYC A Sbjct: 150 LRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNA-EYISKDGLPYCEA 202 >gi|194272204 actin binding LIM protein family, member 2 isoform 5 [Homo sapiens] Length = 531 Score = 42.0 bits (97), Expect = 0.005 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 3 VQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHA 56 ++ C CG + + + +D+ WH CF C+ C +L+ ++S PYC A Sbjct: 150 LRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNA-EYISKDGLPYCEA 202 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.129 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 60,866,644 Number of Sequences: 37866 Number of extensions: 2679452 Number of successful extensions: 9938 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 65 Number of HSP's that attempted gapping in prelim test: 6812 Number of HSP's gapped (non-prelim): 498 length of query: 1695 length of database: 18,247,518 effective HSP length: 116 effective length of query: 1579 effective length of database: 13,855,062 effective search space: 21877142898 effective search space used: 21877142898 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.