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Search of human proteins with 108936950
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|108936950 coiled-coil domain containing 25 [Homo sapiens]
(208 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|108936950 coiled-coil domain containing 25 [Homo sapiens] 424 e-119
gi|169209444 PREDICTED: similar to coiled-coil domain containing... 244 4e-65
gi|169210521 PREDICTED: similar to coiled-coil domain containing... 244 5e-65
gi|169210082 PREDICTED: similar to coiled-coil domain containing... 244 5e-65
gi|145580615 KRI1 homolog [Homo sapiens] 44 1e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 42 4e-04
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 42 4e-04
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 41 6e-04
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 41 6e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 39 0.003
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 39 0.004
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 39 0.004
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 39 0.004
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 39 0.004
gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens] 39 0.004
gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens] 39 0.004
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 38 0.005
gi|20357552 cortactin isoform a [Homo sapiens] 38 0.005
gi|20357556 cortactin isoform b [Homo sapiens] 38 0.005
gi|52426743 cisplatin resistance-associated overexpressed protei... 38 0.005
gi|19923485 cisplatin resistance-associated overexpressed protei... 38 0.005
gi|24308223 hypothetical protein LOC57577 [Homo sapiens] 38 0.005
gi|148746195 trichohyalin [Homo sapiens] 38 0.007
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 38 0.007
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 37 0.012
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 37 0.012
gi|92859701 myosin VI [Homo sapiens] 37 0.012
gi|38044112 restin isoform b [Homo sapiens] 37 0.016
gi|4506751 restin isoform a [Homo sapiens] 37 0.016
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 37 0.016
>gi|108936950 coiled-coil domain containing 25 [Homo sapiens]
Length = 208
Score = 424 bits (1091), Expect = e-119
Identities = 208/208 (100%), Positives = 208/208 (100%)
Query: 1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENI 60
MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENI
Sbjct: 1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENI 60
Query: 61 EDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIV 120
EDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIV
Sbjct: 61 EDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIV 120
Query: 121 TVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREM 180
TVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREM
Sbjct: 121 TVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREM 180
Query: 181 DELRSYSSLMKVENMSSNQDGNDSDEFM 208
DELRSYSSLMKVENMSSNQDGNDSDEFM
Sbjct: 181 DELRSYSSLMKVENMSSNQDGNDSDEFM 208
>gi|169209444 PREDICTED: similar to coiled-coil domain containing 25
[Homo sapiens]
Length = 173
Score = 244 bits (623), Expect = 4e-65
Identities = 125/149 (83%), Positives = 131/149 (87%), Gaps = 3/149 (2%)
Query: 1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENI 60
MVFYFTSSSVNSSA IYMGKDKYENEDL+KHGWPE IWF D+LS AHVYL+LHKGENI
Sbjct: 1 MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI 60
Query: 61 EDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIV 120
EDIPKEVL DCAHLVKANS QGCK NNVNVV TP SNLKKTAD+DV QIGFHRQKDVKIV
Sbjct: 61 EDIPKEVLTDCAHLVKANSTQGCK-NNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIV 119
Query: 121 TVEKKVNEILNRLEKTKVERFPDLAAEKE 149
T+EKKVNEILNRLEKTKVE P A K+
Sbjct: 120 TMEKKVNEILNRLEKTKVE--PGTMAHKK 146
>gi|169210521 PREDICTED: similar to coiled-coil domain containing 25
[Homo sapiens]
Length = 170
Score = 244 bits (622), Expect = 5e-65
Identities = 122/139 (87%), Positives = 127/139 (91%), Gaps = 1/139 (0%)
Query: 1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENI 60
MVFYFTSSSVNSSA IYMGKDKYENEDL+KHGWPE IWF D+LS AHVYL+LHKGENI
Sbjct: 1 MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI 60
Query: 61 EDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIV 120
EDIPKEVL DCAHLVKANS QGCK NNVNVV TP SNLKKTAD+DV QIGFHRQKDVKIV
Sbjct: 61 EDIPKEVLTDCAHLVKANSTQGCK-NNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIV 119
Query: 121 TVEKKVNEILNRLEKTKVE 139
T+EKKVNEILNRLEKTKVE
Sbjct: 120 TMEKKVNEILNRLEKTKVE 138
>gi|169210082 PREDICTED: similar to coiled-coil domain containing 25
[Homo sapiens]
Length = 170
Score = 244 bits (622), Expect = 5e-65
Identities = 122/139 (87%), Positives = 127/139 (91%), Gaps = 1/139 (0%)
Query: 1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENI 60
MVFYFTSSSVNSSA IYMGKDKYENEDL+KHGWPE IWF D+LS AHVYL+LHKGENI
Sbjct: 1 MVFYFTSSSVNSSACAIYMGKDKYENEDLMKHGWPEYIWFRADRLSLAHVYLQLHKGENI 60
Query: 61 EDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIV 120
EDIPKEVL DCAHLVKANS QGCK NNVNVV TP SNLKKTAD+DV QIGFHRQKDVKIV
Sbjct: 61 EDIPKEVLTDCAHLVKANSTQGCK-NNVNVVNTPRSNLKKTADVDVRQIGFHRQKDVKIV 119
Query: 121 TVEKKVNEILNRLEKTKVE 139
T+EKKVNEILNRLEKTKVE
Sbjct: 120 TMEKKVNEILNRLEKTKVE 138
>gi|145580615 KRI1 homolog [Homo sapiens]
Length = 709
Score = 43.9 bits (102), Expect = 1e-04
Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 14/133 (10%)
Query: 84 KMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPD 143
+M V+ P L D G++ +Q+D E+K N + V+ +P
Sbjct: 267 EMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDF-----EQKYNFRFEEPDSASVKTYPR 321
Query: 144 LAAEKECRDREERNEKKAQIQEMKKREK----EEMKKKREMDELRSYSSLMKVENMSSN- 198
A R E R EK+ + +E KKREK EE+K+ + + + L K+ ++ N
Sbjct: 322 SIASSVRRKDERRKEKREETRERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNE 381
Query: 199 ----QDGNDSDEF 207
++G+ D+F
Sbjct: 382 MLGLEEGDLEDDF 394
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 42.0 bits (97), Expect = 4e-04
Identities = 22/88 (25%), Positives = 52/88 (59%), Gaps = 3/88 (3%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE 172
R+++ K+ E+K+ E ++++ + E + E++ R++EE+ ++K QE K RE++
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEMWRQ---EEKIREQEEKRQEKMWRQEKKMREQD 419
Query: 173 EMKKKREMDELRSYSSLMKVENMSSNQD 200
E +++E + R + ++E M +Q+
Sbjct: 420 EKIREQEEEMWRQEEKIRELEEMMQDQE 447
Score = 29.6 bits (65), Expect = 1.9
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 12/81 (14%)
Query: 114 QKDVKIVTVEKKV--NEILNRLEKTKVERFPDLAAEKECRDREE-----RNEKKAQIQEM 166
+++ KI E+K+ E+ R ++ K+ R + E+E + RE+ R E+K + QE
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
Query: 167 KKREKEEM-----KKKREMDE 182
K RE+EE +K RE DE
Sbjct: 361 KIREQEEKMWRQEEKIREQDE 381
Score = 28.9 bits (63), Expect = 3.2
Identities = 22/84 (26%), Positives = 46/84 (54%), Gaps = 6/84 (7%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREER---NEKKAQIQEMKKR 169
R+++ K+ E+K++E + EK + + E++ R++EE+ E+K QE K R
Sbjct: 321 REQEEKMWRQEEKMHE---QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR 377
Query: 170 EKEEMKKKREMDELRSYSSLMKVE 193
E++E +++E + R + + E
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQE 401
Score = 27.3 bits (59), Expect = 9.4
Identities = 18/87 (20%), Positives = 41/87 (47%)
Query: 114 QKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEE 173
++ K+ EKK+ E ++ + + E + +E + + E+K + E K +E+EE
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 174 MKKKREMDELRSYSSLMKVENMSSNQD 200
+++E R + + E + Q+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Score = 27.3 bits (59), Expect = 9.4
Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 113 RQKDVKIVTVEKKV---NEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKR 169
R++D KI E+++ E + LE+ ++ L +E ++ + E+K Q QE K +
Sbjct: 416 REQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL---REVEEKMQEEEEKMQEQEEKIQ 472
Query: 170 EKEEMKKKREMDELRSYSSLMKVENMSSNQD 200
+EE +++E R L + E + ++
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Score = 27.3 bits (59), Expect = 9.4
Identities = 25/76 (32%), Positives = 46/76 (60%), Gaps = 10/76 (13%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKT-KVERFPDLAAEKECRDREE---RNEKKAQIQEMKK 168
++++ KI E+K+ E + EKT + E+ L E++ ++EE R E+K QE K
Sbjct: 465 QEQEEKIQRQEEKIQE---QEEKTWRQEKL--LKQEEKIWEQEEKMWRQEEKMWEQEEKM 519
Query: 169 REKEEMKKKREMDELR 184
+E+EE K +R+ +++R
Sbjct: 520 QEQEE-KMQRQEEKMR 534
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 42.0 bits (97), Expect = 4e-04
Identities = 22/88 (25%), Positives = 52/88 (59%), Gaps = 3/88 (3%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE 172
R+++ K+ E+K+ E ++++ + E + E++ R++EE+ ++K QE K RE++
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEMWRQ---EEKIREQEEKRQEKMWRQEKKMREQD 419
Query: 173 EMKKKREMDELRSYSSLMKVENMSSNQD 200
E +++E + R + ++E M +Q+
Sbjct: 420 EKIREQEEEMWRQEEKIRELEEMMQDQE 447
Score = 29.6 bits (65), Expect = 1.9
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 12/81 (14%)
Query: 114 QKDVKIVTVEKKV--NEILNRLEKTKVERFPDLAAEKECRDREE-----RNEKKAQIQEM 166
+++ KI E+K+ E+ R ++ K+ R + E+E + RE+ R E+K + QE
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
Query: 167 KKREKEEM-----KKKREMDE 182
K RE+EE +K RE DE
Sbjct: 361 KIREQEEKMWRQEEKIREQDE 381
Score = 28.9 bits (63), Expect = 3.2
Identities = 22/84 (26%), Positives = 46/84 (54%), Gaps = 6/84 (7%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREER---NEKKAQIQEMKKR 169
R+++ K+ E+K++E + EK + + E++ R++EE+ E+K QE K R
Sbjct: 321 REQEEKMWRQEEKMHE---QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR 377
Query: 170 EKEEMKKKREMDELRSYSSLMKVE 193
E++E +++E + R + + E
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQE 401
Score = 27.3 bits (59), Expect = 9.4
Identities = 18/87 (20%), Positives = 41/87 (47%)
Query: 114 QKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEE 173
++ K+ EKK+ E ++ + + E + +E + + E+K + E K +E+EE
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 174 MKKKREMDELRSYSSLMKVENMSSNQD 200
+++E R + + E + Q+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Score = 27.3 bits (59), Expect = 9.4
Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 113 RQKDVKIVTVEKKV---NEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKR 169
R++D KI E+++ E + LE+ ++ L +E ++ + E+K Q QE K +
Sbjct: 416 REQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL---REVEEKMQEEEEKMQEQEEKIQ 472
Query: 170 EKEEMKKKREMDELRSYSSLMKVENMSSNQD 200
+EE +++E R L + E + ++
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Score = 27.3 bits (59), Expect = 9.4
Identities = 25/76 (32%), Positives = 46/76 (60%), Gaps = 10/76 (13%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKT-KVERFPDLAAEKECRDREE---RNEKKAQIQEMKK 168
++++ KI E+K+ E + EKT + E+ L E++ ++EE R E+K QE K
Sbjct: 465 QEQEEKIQRQEEKIQE---QEEKTWRQEKL--LKQEEKIWEQEEKMWRQEEKMWEQEEKM 519
Query: 169 REKEEMKKKREMDELR 184
+E+EE K +R+ +++R
Sbjct: 520 QEQEE-KMQRQEEKMR 534
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 41.2 bits (95), Expect = 6e-04
Identities = 23/79 (29%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE 172
R KD +T +K+V+ + + K +R D +KE ++R++++E+K + +E K+++E
Sbjct: 36 RPKDDIKLTAKKEVS----KAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEE 91
Query: 173 EMKKKREMDELRSYSSLMK 191
E KKK + +E + K
Sbjct: 92 EEKKKHQEEERKKQEEQAK 110
Score = 36.2 bits (82), Expect = 0.020
Identities = 33/125 (26%), Positives = 62/125 (49%), Gaps = 21/125 (16%)
Query: 94 PWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDR 153
P ++K TA +V + ++K ++ +K+ E R +K + + + AE+E + +
Sbjct: 37 PKDDIKLTAKKEVSKAPEDKKKRLED---DKRKKEDKERKKKDEEK----VKAEEESKKK 89
Query: 154 EERNEKKAQIQEMKKREKE-----------EMKKKREMDELRSYS---SLMKVENMSSNQ 199
EE +KK Q +E KK+E++ +MK+K E +L + ++ E S NQ
Sbjct: 90 EEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQ 149
Query: 200 DGNDS 204
+ DS
Sbjct: 150 NAPDS 154
Score = 30.0 bits (66), Expect = 1.5
Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 8/102 (7%)
Query: 99 KKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNE 158
KK A M+ +KD EK +E K + + L A+KE E +
Sbjct: 6 KKPASME--------EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKK 57
Query: 159 KKAQIQEMKKREKEEMKKKREMDELRSYSSLMKVENMSSNQD 200
K+ + + KK +KE KK E + S + E +Q+
Sbjct: 58 KRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE 99
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 41.2 bits (95), Expect = 6e-04
Identities = 23/79 (29%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE 172
R KD +T +K+V+ + + K +R D +KE ++R++++E+K + +E K+++E
Sbjct: 36 RPKDDIKLTAKKEVS----KAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEE 91
Query: 173 EMKKKREMDELRSYSSLMK 191
E KKK + +E + K
Sbjct: 92 EEKKKHQEEERKKQEEQAK 110
Score = 36.2 bits (82), Expect = 0.020
Identities = 33/125 (26%), Positives = 62/125 (49%), Gaps = 21/125 (16%)
Query: 94 PWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDR 153
P ++K TA +V + ++K ++ +K+ E R +K + + + AE+E + +
Sbjct: 37 PKDDIKLTAKKEVSKAPEDKKKRLED---DKRKKEDKERKKKDEEK----VKAEEESKKK 89
Query: 154 EERNEKKAQIQEMKKREKE-----------EMKKKREMDELRSYS---SLMKVENMSSNQ 199
EE +KK Q +E KK+E++ +MK+K E +L + ++ E S NQ
Sbjct: 90 EEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQ 149
Query: 200 DGNDS 204
+ DS
Sbjct: 150 NAPDS 154
Score = 30.0 bits (66), Expect = 1.5
Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 8/102 (7%)
Query: 99 KKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNE 158
KK A M+ +KD EK +E K + + L A+KE E +
Sbjct: 6 KKPASME--------EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKK 57
Query: 159 KKAQIQEMKKREKEEMKKKREMDELRSYSSLMKVENMSSNQD 200
K+ + + KK +KE KK E + S + E +Q+
Sbjct: 58 KRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE 99
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 38.9 bits (89), Expect = 0.003
Identities = 24/89 (26%), Positives = 48/89 (53%), Gaps = 2/89 (2%)
Query: 113 RQKDVKIVTVEKKVN--EILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKRE 170
++ D K+ +EK+ + EI R + + ER +L E+E +ER + + + QE +K
Sbjct: 486 KRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKEL 545
Query: 171 KEEMKKKREMDELRSYSSLMKVENMSSNQ 199
++E +K+REM++ R ++E +
Sbjct: 546 EKEQEKQREMEKERKQEKEKELERQKEKE 574
Score = 36.2 bits (82), Expect = 0.020
Identities = 26/83 (31%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE-EMKKKREMD 181
++K E+ EK + E + EKE ++ E + EK+ ++Q+MK++EKE E++K+RE
Sbjct: 539 QEKEKELEKEQEKQR-EMEKERKQEKE-KELERQKEKEKELQKMKEQEKECELEKEREKL 596
Query: 182 ELRSYSSLMKVENMSSNQDGNDS 204
E + +E M Q+ +S
Sbjct: 597 EEKIEPREPNLEPMVEKQESENS 619
Score = 30.4 bits (67), Expect = 1.1
Identities = 21/93 (22%), Positives = 47/93 (50%), Gaps = 4/93 (4%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECR---DREERNEKKAQIQEMKKR 169
R+K+++ +++ E E+ + E+ +L E+E + ++E + EK+ +++ K++
Sbjct: 515 REKELEKEQEQEREKEREKDRERQQ-EKEKELEKEQEKQREMEKERKQEKEKELERQKEK 573
Query: 170 EKEEMKKKREMDELRSYSSLMKVENMSSNQDGN 202
EKE K K + E K+E ++ N
Sbjct: 574 EKELQKMKEQEKECELEKEREKLEEKIEPREPN 606
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 38.5 bits (88), Expect = 0.004
Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 6/62 (9%)
Query: 128 EILNRLEKTKV------ERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMD 181
E L +LEK K R ++ A++E +R+ + E + Q +E+ +R++EE +K+RE +
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
Query: 182 EL 183
EL
Sbjct: 778 EL 779
Score = 29.6 bits (65), Expect = 1.9
Identities = 12/51 (23%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
Query: 134 EKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELR 184
E + +R ++A ++ R+ EER +++ ++ +++R +EE +++++ + LR
Sbjct: 786 EALRRQREQEIALRRQ-REEEERQQQEEALRRLEERRREEEERRKQEELLR 835
Score = 28.5 bits (62), Expect = 4.2
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
Query: 108 QIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMK 167
+I RQ++ + ++ E L RLE+ + E E+E R +EE K+ +
Sbjct: 795 EIALRRQREEE---ERQQQEEALRRLEERRRE-------EEERRKQEELLRKQEEEAAKW 844
Query: 168 KREKEEMKKKREMDELR 184
RE+EE +++ E + LR
Sbjct: 845 AREEEEAQRRLEENRLR 861
Score = 27.7 bits (60), Expect = 7.2
Identities = 15/62 (24%), Positives = 39/62 (62%), Gaps = 3/62 (4%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKE--CRDREERNEKKAQIQEMKKREKEE-MKKKRE 179
E++ E+ + E+ + +R +L ++E R ++E K+ + +E+ +R++EE ++++RE
Sbjct: 734 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 793
Query: 180 MD 181
+
Sbjct: 794 QE 795
Score = 27.3 bits (59), Expect = 9.4
Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 4/68 (5%)
Query: 124 KKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDEL 183
+K E+L + E+ + + E+E + R E N + + + + R +EE +K++E+ E+
Sbjct: 828 RKQEELLRKQEEEAAKWARE---EEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL-EV 883
Query: 184 RSYSSLMK 191
+ LM+
Sbjct: 884 QRQKELMR 891
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 38.5 bits (88), Expect = 0.004
Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 6/62 (9%)
Query: 128 EILNRLEKTKV------ERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMD 181
E L +LEK K R ++ A++E +R+ + E + Q +E+ +R++EE +K+RE +
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
Query: 182 EL 183
EL
Sbjct: 805 EL 806
Score = 29.6 bits (65), Expect = 1.9
Identities = 12/51 (23%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
Query: 134 EKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELR 184
E + +R ++A ++ R+ EER +++ ++ +++R +EE +++++ + LR
Sbjct: 813 EALRRQREQEIALRRQ-REEEERQQQEEALRRLEERRREEEERRKQEELLR 862
Score = 28.5 bits (62), Expect = 4.2
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
Query: 108 QIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMK 167
+I RQ++ + ++ E L RLE+ + E E+E R +EE K+ +
Sbjct: 822 EIALRRQREEE---ERQQQEEALRRLEERRRE-------EEERRKQEELLRKQEEEAAKW 871
Query: 168 KREKEEMKKKREMDELR 184
RE+EE +++ E + LR
Sbjct: 872 AREEEEAQRRLEENRLR 888
Score = 27.7 bits (60), Expect = 7.2
Identities = 15/62 (24%), Positives = 39/62 (62%), Gaps = 3/62 (4%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKE--CRDREERNEKKAQIQEMKKREKEE-MKKKRE 179
E++ E+ + E+ + +R +L ++E R ++E K+ + +E+ +R++EE ++++RE
Sbjct: 761 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 820
Query: 180 MD 181
+
Sbjct: 821 QE 822
Score = 27.3 bits (59), Expect = 9.4
Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 4/68 (5%)
Query: 124 KKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDEL 183
+K E+L + E+ + + E+E + R E N + + + + R +EE +K++E+ E+
Sbjct: 855 RKQEELLRKQEEEAAKWARE---EEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL-EV 910
Query: 184 RSYSSLMK 191
+ LM+
Sbjct: 911 QRQKELMR 918
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 38.5 bits (88), Expect = 0.004
Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 6/62 (9%)
Query: 128 EILNRLEKTKV------ERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMD 181
E L +LEK K R ++ A++E +R+ + E + Q +E+ +R++EE +K+RE +
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
Query: 182 EL 183
EL
Sbjct: 784 EL 785
Score = 29.6 bits (65), Expect = 1.9
Identities = 12/51 (23%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
Query: 134 EKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELR 184
E + +R ++A ++ R+ EER +++ ++ +++R +EE +++++ + LR
Sbjct: 792 EALRRQREQEIALRRQ-REEEERQQQEEALRRLEERRREEEERRKQEELLR 841
Score = 28.5 bits (62), Expect = 4.2
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
Query: 108 QIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMK 167
+I RQ++ + ++ E L RLE+ + E E+E R +EE K+ +
Sbjct: 801 EIALRRQREEE---ERQQQEEALRRLEERRRE-------EEERRKQEELLRKQEEEAAKW 850
Query: 168 KREKEEMKKKREMDELR 184
RE+EE +++ E + LR
Sbjct: 851 AREEEEAQRRLEENRLR 867
Score = 27.7 bits (60), Expect = 7.2
Identities = 15/62 (24%), Positives = 39/62 (62%), Gaps = 3/62 (4%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKE--CRDREERNEKKAQIQEMKKREKEE-MKKKRE 179
E++ E+ + E+ + +R +L ++E R ++E K+ + +E+ +R++EE ++++RE
Sbjct: 740 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 799
Query: 180 MD 181
+
Sbjct: 800 QE 801
Score = 27.3 bits (59), Expect = 9.4
Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 4/68 (5%)
Query: 124 KKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDEL 183
+K E+L + E+ + + E+E + R E N + + + + R +EE +K++E+ E+
Sbjct: 834 RKQEELLRKQEEEAAKWARE---EEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL-EV 889
Query: 184 RSYSSLMK 191
+ LM+
Sbjct: 890 QRQKELMR 897
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 38.5 bits (88), Expect = 0.004
Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 6/62 (9%)
Query: 128 EILNRLEKTKV------ERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMD 181
E L +LEK K R ++ A++E +R+ + E + Q +E+ +R++EE +K+RE +
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
Query: 182 EL 183
EL
Sbjct: 784 EL 785
Score = 29.6 bits (65), Expect = 1.9
Identities = 12/51 (23%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
Query: 134 EKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELR 184
E + +R ++A ++ R+ EER +++ ++ +++R +EE +++++ + LR
Sbjct: 792 EALRRQREQEIALRRQ-REEEERQQQEEALRRLEERRREEEERRKQEELLR 841
Score = 28.5 bits (62), Expect = 4.2
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
Query: 108 QIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMK 167
+I RQ++ + ++ E L RLE+ + E E+E R +EE K+ +
Sbjct: 801 EIALRRQREEE---ERQQQEEALRRLEERRRE-------EEERRKQEELLRKQEEEAAKW 850
Query: 168 KREKEEMKKKREMDELR 184
RE+EE +++ E + LR
Sbjct: 851 AREEEEAQRRLEENRLR 867
Score = 27.7 bits (60), Expect = 7.2
Identities = 15/62 (24%), Positives = 39/62 (62%), Gaps = 3/62 (4%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKE--CRDREERNEKKAQIQEMKKREKEE-MKKKRE 179
E++ E+ + E+ + +R +L ++E R ++E K+ + +E+ +R++EE ++++RE
Sbjct: 740 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 799
Query: 180 MD 181
+
Sbjct: 800 QE 801
Score = 27.3 bits (59), Expect = 9.4
Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 4/68 (5%)
Query: 124 KKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDEL 183
+K E+L + E+ + + E+E + R E N + + + + R +EE +K++E+ E+
Sbjct: 834 RKQEELLRKQEEEAAKWARE---EEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL-EV 889
Query: 184 RSYSSLMK 191
+ LM+
Sbjct: 890 QRQKELMR 897
>gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens]
Length = 325
Score = 38.5 bits (88), Expect = 0.004
Identities = 21/83 (25%), Positives = 44/83 (53%), Gaps = 5/83 (6%)
Query: 123 EKKVNEILNRLEKTKV-----ERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKK 177
E+KV E+ +L+ + E+ P K+ R RE+ ++ +++ EKE+ +
Sbjct: 69 ERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLN 128
Query: 178 REMDELRSYSSLMKVENMSSNQD 200
E+ EL+ + L+K +N +N++
Sbjct: 129 EELHELKEENKLLKGKNTLANKE 151
>gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens]
Length = 325
Score = 38.5 bits (88), Expect = 0.004
Identities = 21/83 (25%), Positives = 44/83 (53%), Gaps = 5/83 (6%)
Query: 123 EKKVNEILNRLEKTKV-----ERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKK 177
E+KV E+ +L+ + E+ P K+ R RE+ ++ +++ EKE+ +
Sbjct: 69 ERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLN 128
Query: 178 REMDELRSYSSLMKVENMSSNQD 200
E+ EL+ + L+K +N +N++
Sbjct: 129 EELHELKEENKLLKGKNTLANKE 151
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 38.1 bits (87), Expect = 0.005
Identities = 20/70 (28%), Positives = 42/70 (60%), Gaps = 5/70 (7%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE 172
R+K+ ++ EK ++ E+ K++ EK+ RD+EE+ +++ +I+E +K+ +E
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQE-----QEKKTRDQEEKMQEEERIREREKKMRE 461
Query: 173 EMKKKREMDE 182
E + RE +E
Sbjct: 462 EEETMREQEE 471
Score = 35.8 bits (81), Expect = 0.027
Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 12/101 (11%)
Query: 108 QIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMK 167
Q G R+++ K+ EK++ E L + EKE R+++E E++ Q+QE +
Sbjct: 305 QEGKMREQEEKMWRQEKRLREQEKELREQ----------EKELREQKELREQEEQMQEQE 354
Query: 168 KREKEEMKKKREMDE--LRSYSSLMKVENMSSNQDGNDSDE 206
++ E+ +K RE +E R L + E Q+ D+
Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395
Score = 34.3 bits (77), Expect = 0.077
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 147 EKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELRSYSSLMKVE 193
E++ D+EER EKK Q QE K ++EE K RE + +R M+ E
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEE--KMREEERMREREKKMREE 601
Score = 32.7 bits (73), Expect = 0.22
Identities = 22/68 (32%), Positives = 41/68 (60%), Gaps = 8/68 (11%)
Query: 114 QKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREE--RNEKKAQIQEMKKREK 171
+++ K+ E+K+ + R+EK E+ EK+ D+EE R E++ + +E K RE+
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQ------EKKTWDQEEKMREEERMREREKKMREE 601
Query: 172 EEMKKKRE 179
EEM +++E
Sbjct: 602 EEMMREQE 609
Score = 30.4 bits (67), Expect = 1.1
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 6/82 (7%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREE-RNEKKAQIQEMKKREK 171
R+++ K+ E+++ E RL + K ER + EK E+ R EKK Q QE K R++
Sbjct: 386 REQEQKMRDQEERMWEQDERLRE-KEERMRE--QEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 172 EEMKKKREMDELRSYSSLMKVE 193
EE K +E + +R M+ E
Sbjct: 443 EE--KMQEEERIREREKKMREE 462
Score = 29.3 bits (64), Expect = 2.5
Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 8/72 (11%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREK---EEMKKKRE 179
EKK+ R ++ K+ R + E+E + RE+ + Q + ++++EK E+ K+ RE
Sbjct: 285 EKKI-----RKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE 339
Query: 180 MDELRSYSSLMK 191
ELR M+
Sbjct: 340 QKELREQEEQMQ 351
Score = 29.3 bits (64), Expect = 2.5
Identities = 15/49 (30%), Positives = 28/49 (57%)
Query: 134 EKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDE 182
E K++ + ++E +E+ EKK Q QE K ++E+M+++ M E
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRE 717
Score = 29.3 bits (64), Expect = 2.5
Identities = 22/67 (32%), Positives = 39/67 (58%), Gaps = 8/67 (11%)
Query: 114 QKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREE-RNEKKAQIQEMKKREKE 172
Q+ K+ E+K+ E ++EK E+ EK+ D+E+ R E+ + +E K RE+E
Sbjct: 674 QEQEKMQEQEEKIWE-QEKMEKKTQEQ------EKKTWDQEKMREEESMREREKKMREEE 726
Query: 173 EMKKKRE 179
EM +++E
Sbjct: 727 EMMREQE 733
Score = 28.9 bits (63), Expect = 3.2
Identities = 20/73 (27%), Positives = 38/73 (52%), Gaps = 4/73 (5%)
Query: 132 RLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREK---EEMKKKREMD-ELRSYS 187
R ++ K+ + + +E R RE+ + + Q ++M ++EK E+ K+ RE + ELR
Sbjct: 282 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK 341
Query: 188 SLMKVENMSSNQD 200
L + E Q+
Sbjct: 342 ELREQEEQMQEQE 354
Score = 28.9 bits (63), Expect = 3.2
Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 6/91 (6%)
Query: 95 WSNLKKTADMDVGQIGFHRQKDVKIVTVEKKV--NEILNRLEKTKVERFPDLAAEKEC-R 151
W +K D + + + K EKK E R E+ ER + E+E R
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 606
Query: 152 DREER---NEKKAQIQEMKKREKEEMKKKRE 179
++EE+ E+K Q QE K E+EE +++E
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQE 637
Score = 28.9 bits (63), Expect = 3.2
Identities = 16/45 (35%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 147 EKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELRSYSSLMK 191
E++ +EE+ E+K Q QE K RE+EE K + + +++R M+
Sbjct: 842 EEKMWGQEEKMEEKMQGQEEKMREQEE-KMRGQEEKMREQEEKMR 885
Score = 27.7 bits (60), Expect = 7.2
Identities = 16/61 (26%), Positives = 33/61 (54%)
Query: 122 VEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMD 181
+EKK E + + R + E+E + REE + Q ++M+++E++ +++ EM
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751
Query: 182 E 182
E
Sbjct: 752 E 752
>gi|20357552 cortactin isoform a [Homo sapiens]
Length = 550
Score = 38.1 bits (87), Expect = 0.005
Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Query: 105 DVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQ 164
DV Q+ QK V + V K + I F +LA EKE DR + ++AQ
Sbjct: 326 DVTQVSSAYQKTVPVEAVTSKTSNIR--------ANFENLAKEKEQEDRRKAEAERAQRM 377
Query: 165 EMKKREKEEMKKKRE 179
+++E+EE ++K E
Sbjct: 378 AKERQEQEEARRKLE 392
>gi|20357556 cortactin isoform b [Homo sapiens]
Length = 513
Score = 38.1 bits (87), Expect = 0.005
Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Query: 105 DVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQ 164
DV Q+ QK V + V K + I F +LA EKE DR + ++AQ
Sbjct: 289 DVTQVSSAYQKTVPVEAVTSKTSNIR--------ANFENLAKEKEQEDRRKAEAERAQRM 340
Query: 165 EMKKREKEEMKKKRE 179
+++E+EE ++K E
Sbjct: 341 AKERQEQEEARRKLE 355
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 38.1 bits (87), Expect = 0.005
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 4/83 (4%)
Query: 122 VEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQE----MKKREKEEMKKK 177
++ V E+ +L K E D +KE ++REER +++ + +E ++RE+EE +K+
Sbjct: 223 IKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKE 282
Query: 178 REMDELRSYSSLMKVENMSSNQD 200
R D R S + + S D
Sbjct: 283 RARDRERRKRSRSRSRHSSRTSD 305
Score = 29.6 bits (65), Expect = 1.9
Identities = 16/53 (30%), Positives = 30/53 (56%)
Query: 132 RLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELR 184
+++ T E L E DR+ER +K+ Q +E +++E+E +++RE R
Sbjct: 222 KIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
Score = 27.7 bits (60), Expect = 7.2
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 121 TVEKKVNEILNRLEKTKVERFPDLAAEKECRDR------EERNEKKAQIQEMKKREKEEM 174
T E +E L + ++ + ER + E+E R+R EER +++A+ +E +KR +
Sbjct: 238 TEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRS 297
Query: 175 KKKREMDELR 184
+ + R
Sbjct: 298 RHSSRTSDRR 307
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 38.1 bits (87), Expect = 0.005
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 4/83 (4%)
Query: 122 VEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQE----MKKREKEEMKKK 177
++ V E+ +L K E D +KE ++REER +++ + +E ++RE+EE +K+
Sbjct: 223 IKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKE 282
Query: 178 REMDELRSYSSLMKVENMSSNQD 200
R D R S + + S D
Sbjct: 283 RARDRERRKRSRSRSRHSSRTSD 305
Score = 29.6 bits (65), Expect = 1.9
Identities = 16/53 (30%), Positives = 30/53 (56%)
Query: 132 RLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELR 184
+++ T E L E DR+ER +K+ Q +E +++E+E +++RE R
Sbjct: 222 KIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
Score = 27.7 bits (60), Expect = 7.2
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 121 TVEKKVNEILNRLEKTKVERFPDLAAEKECRDR------EERNEKKAQIQEMKKREKEEM 174
T E +E L + ++ + ER + E+E R+R EER +++A+ +E +KR +
Sbjct: 238 TEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRS 297
Query: 175 KKKREMDELR 184
+ + R
Sbjct: 298 RHSSRTSDRR 307
>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
Length = 936
Score = 38.1 bits (87), Expect = 0.005
Identities = 18/65 (27%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Query: 129 ILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELRSYSS 188
+ + +K + E+ L A++E R + E EK+AQ++ +KRE++ +KK +E+++ +
Sbjct: 675 LAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLE--RKREEKRLKKMKELEKQKRIKR 732
Query: 189 LMKVE 193
++E
Sbjct: 733 NQQLE 737
Score = 37.4 bits (85), Expect = 0.009
Identities = 25/78 (32%), Positives = 43/78 (55%), Gaps = 7/78 (8%)
Query: 129 ILNRLEKTKVERFPD---LAAEKECRDREERNEKKAQIQEMKKREKEE----MKKKREMD 181
IL +E+ ++R LA +K+ ++ E+ + KAQ +E +KRE EE +++KRE
Sbjct: 657 ILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEK 716
Query: 182 ELRSYSSLMKVENMSSNQ 199
L+ L K + + NQ
Sbjct: 717 RLKKMKELEKQKRIKRNQ 734
Score = 29.6 bits (65), Expect = 1.9
Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDE 182
+K+ E L +L+ + ER A EKE + +R EK+ +++MK+ EK++ K+ + E
Sbjct: 680 KKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKR--LKKMKELEKQKRIKRNQQLE 737
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 37.7 bits (86), Expect = 0.007
Identities = 17/66 (25%), Positives = 39/66 (59%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDE 182
E+++ + + + + ER+ + E++ R E + + Q ++ K RE+E+++++RE +
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Query: 183 LRSYSS 188
LRS S
Sbjct: 1788 LRSQES 1793
Score = 35.0 bits (79), Expect = 0.045
Identities = 18/77 (23%), Positives = 41/77 (53%), Gaps = 5/77 (6%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDE 182
E++ +++L R E+ + +R ++E +R E+ K+ +++ +++ E+ E + KRE E
Sbjct: 572 EERRDQLLKREEERRQQRL-----KREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 183 LRSYSSLMKVENMSSNQ 199
L+K E +
Sbjct: 627 EERRQQLLKSEEQEERR 643
Score = 33.9 bits (76), Expect = 0.10
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE 172
RQ+ + + E+++ + + ER E++ R E + ++Q + K RE+E
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEE 1801
Query: 173 EMKKKREMDELR 184
+++++RE +LR
Sbjct: 1802 QLRQEREEQQLR 1813
Score = 33.5 bits (75), Expect = 0.13
Identities = 20/71 (28%), Positives = 45/71 (63%), Gaps = 2/71 (2%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE 172
R+++++ E+K E +L + + +R L E++ R R+ER +++ Q ++ K RE+E
Sbjct: 1504 REQELRSQEPERKFLEEEQQLHRQQRQR-KFLQEEQQLR-RQERGQQRRQDRDRKFREEE 1561
Query: 173 EMKKKREMDEL 183
+++++RE +L
Sbjct: 1562 QLRQEREEQQL 1572
Score = 32.7 bits (73), Expect = 0.22
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPD--LAAEKECRDREERNEKKAQIQEMKKRE 170
RQ+ + + ++ +E RLE+ +R + +E ++REER ++ Q+Q K E
Sbjct: 141 RQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHE 200
Query: 171 KEEMK-----KKREMDELRSYSSLMKVENMSSNQD 200
EE ++RE+ ELR K + QD
Sbjct: 201 TEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
Score = 31.2 bits (69), Expect = 0.65
Identities = 14/36 (38%), Positives = 25/36 (69%)
Query: 144 LAAEKECRDREERNEKKAQIQEMKKREKEEMKKKRE 179
L E+E REER +++ Q QE + RE+E+++++ E
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEE 941
Score = 31.2 bits (69), Expect = 0.65
Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Query: 128 EILNRLEKTKVERFPDLAAEKECRDREERNEKKA-QIQEMKKREKEEMKKKREMDELR 184
E L R E+ + +R + E++ REER EK+ Q + K RE+E++ ++RE LR
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Score = 30.8 bits (68), Expect = 0.85
Identities = 19/67 (28%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE 172
+QK+ +++ E + R +K + E +L E+E REER +++ Q E + R+K+
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEE--ELQQEEEQLLREEREKRRRQEWERQYRKKD 1024
Query: 173 EMKKKRE 179
E++++ E
Sbjct: 1025 ELQQEEE 1031
Score = 30.8 bits (68), Expect = 0.85
Identities = 18/80 (22%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQI--QEMKKREKEEMKKKREM 180
E++V + +L + + E+ E++ R+ EE +++ Q+ +E +KR +E ++ RE
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
Query: 181 DELRSYSSLMKVENMSSNQD 200
+EL+ + + D
Sbjct: 1203 EELQRQKRKQRYRDEDQRSD 1222
Score = 30.4 bits (67), Expect = 1.1
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEK--ECRDREERNEKKAQIQEMKKRE 170
++++V+ + E++ + L R E + R L +E+ E R ++ R E++ + ++ KRE
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 171 KEE----MKKKREMDELRSYSSLMKVENMSSNQ 199
+EE + KRE +E R L + E + +
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARE 695
Score = 30.4 bits (67), Expect = 1.1
Identities = 14/37 (37%), Positives = 26/37 (70%)
Query: 143 DLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKRE 179
+L E+E REER +++ Q +E + RE+EE++++ E
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
Score = 30.0 bits (66), Expect = 1.5
Identities = 17/77 (22%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDE 182
E++ + R ++ + E+ + ++ R++EER E+ Q++ ++ E+ E + +RE +E
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQ--QLRREQEEERREQQLRREQEE 370
Query: 183 LRSYSSLMKVENMSSNQ 199
R L + + + Q
Sbjct: 371 ERREQQLRREQQLRREQ 387
Score = 30.0 bits (66), Expect = 1.5
Identities = 24/90 (26%), Positives = 50/90 (55%), Gaps = 7/90 (7%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECR-DREERNEKKAQIQEMKKREK 171
R++ ++ E++ + + E+ ++++ L +E++ R ++EER E+ + +E K+ E+
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQ--RLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Query: 172 E--EMKKKREMDELRSYSSLMKVENMSSNQ 199
E E + KRE +E R L+K E Q
Sbjct: 561 ERREQRLKREQEERR--DQLLKREEERRQQ 588
Score = 29.6 bits (65), Expect = 1.9
Identities = 17/66 (25%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
Query: 130 LNRLEKTKVERFPDLAAEKECRDR---EERNEKKAQIQEMKKREKEEMKKKREMDELRSY 186
L R E+ + R + ++ R+R +E + + Q E K RE+E+++++ E ++LR
Sbjct: 1684 LRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ 1743
Query: 187 SSLMKV 192
K+
Sbjct: 1744 ERYRKI 1749
Score = 29.3 bits (64), Expect = 2.5
Identities = 20/75 (26%), Positives = 43/75 (57%), Gaps = 3/75 (4%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQI--QEMKKRE 170
RQ+ + +KK+ + +L + E+ EK+ R+ EE +++ Q+ +E +KR
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Query: 171 KEEMKKK-REMDELR 184
++E +++ R+ DEL+
Sbjct: 1013 RQEWERQYRKKDELQ 1027
Score = 29.3 bits (64), Expect = 2.5
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 4/47 (8%)
Query: 144 LAAEKECRDREERNEKKAQIQEMKKRE----KEEMKKKREMDELRSY 186
L E E R R+ER +K + +E+++ E +EE +K+R + R Y
Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Score = 28.9 bits (63), Expect = 3.2
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 7/74 (9%)
Query: 118 KIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDRE---ERNEKKAQIQEMKKR----E 170
+++ + +K E + + + +R EKE R RE + E+K Q +E +++ E
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 171 KEEMKKKREMDELR 184
+EE +K E ELR
Sbjct: 274 EEEQLRKLERQELR 287
Score = 28.9 bits (63), Expect = 3.2
Identities = 20/91 (21%), Positives = 46/91 (50%), Gaps = 10/91 (10%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE 172
R+++ + E++ ++ E+ + ER+ L + EER E++ + ++ +RE+E
Sbjct: 460 REEETERHEQERRKQQLKRDQEEERRERWLKL-------EEEERREQQERREQQLRREQE 512
Query: 173 EMKK---KREMDELRSYSSLMKVENMSSNQD 200
E ++ KR+ +E R L + + Q+
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Score = 28.9 bits (63), Expect = 3.2
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query: 132 RLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKK---KREMDELR 184
RL++ +VER ++ REE E++ Q Q +K E+EE ++ +RE E R
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQ-QLLKSEEQEERRQQQLRREQQERR 655
Score = 28.9 bits (63), Expect = 3.2
Identities = 14/37 (37%), Positives = 25/37 (67%)
Query: 143 DLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKRE 179
+L E+E REER +++ Q E + RE+EE++++ E
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEE 1151
Score = 28.5 bits (62), Expect = 4.2
Identities = 13/49 (26%), Positives = 27/49 (55%)
Query: 151 RDREERNEKKAQIQEMKKREKEEMKKKREMDELRSYSSLMKVENMSSNQ 199
RDR+ R E++ QE +RE++E+ ++ E + ++ E++ Q
Sbjct: 1841 RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889
Score = 28.1 bits (61), Expect = 5.5
Identities = 21/92 (22%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQI--QEMKKRE 170
RQ+ + E+++ + +L + + E+ E++ R+ EE +++ Q+ +E +KR
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Query: 171 KEEMKKK-REMDEL-RSYSSLMKVENMSSNQD 200
++E++++ RE +EL + L++ E Q+
Sbjct: 1163 RQELERQYREEEELQQEEEQLLREEQEKRRQE 1194
Score = 28.1 bits (61), Expect = 5.5
Identities = 17/52 (32%), Positives = 37/52 (71%), Gaps = 3/52 (5%)
Query: 134 EKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELRS 185
EK++ E +L E+E + R+ER E+K + + +++++KEE ++ R++ E++S
Sbjct: 1855 EKSRREE-QELWQEEEQKRRQER-ERKLREEHIRRQQKEE-QRHRQVGEIKS 1903
Score = 27.7 bits (60), Expect = 7.2
Identities = 14/64 (21%), Positives = 33/64 (51%), Gaps = 4/64 (6%)
Query: 147 EKECRDREERNEKKAQIQEMKKRE----KEEMKKKREMDELRSYSSLMKVENMSSNQDGN 202
E+E R R+E+ + + +++++ E +EE +K+R + R Y K++ G
Sbjct: 917 EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE 976
Query: 203 DSDE 206
+ ++
Sbjct: 977 EPEK 980
Score = 27.3 bits (59), Expect = 9.4
Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 4/64 (6%)
Query: 134 EKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKRE----KEEMKKKREMDELRSYSSL 189
E+ + E L E E R R+ER + + +E+++ E +EE +K+R + R Y
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143
Query: 190 MKVE 193
+V+
Sbjct: 1144 EEVQ 1147
Score = 27.3 bits (59), Expect = 9.4
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 15/95 (15%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEM-------- 174
EK+ + L R + + E + E+E REE +++ Q E + RE+EE+
Sbjct: 1129 EKRRRQELERQYREEEE----VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184
Query: 175 ---KKKREMDELRSYSSLMKVENMSSNQDGNDSDE 206
++KR + R Y +++ Q D D+
Sbjct: 1185 REEQEKRRQERERQYREEEELQRQKRKQRYRDEDQ 1219
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 37.7 bits (86), Expect = 0.007
Identities = 27/91 (29%), Positives = 50/91 (54%), Gaps = 4/91 (4%)
Query: 113 RQKDVKIVTVE-KKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREK 171
++K+ +IV ++ +K E L R + DL AEKE + EER ++ +I+ KKR++
Sbjct: 640 QRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKE-KFEEERLREQQEIELQKKRQE 698
Query: 172 EE--MKKKREMDELRSYSSLMKVENMSSNQD 200
EE ++ + E+ L+ ++ K E Q+
Sbjct: 699 EETFLRVQEELQRLKELNNNEKAEKFQIFQE 729
Score = 30.8 bits (68), Expect = 0.85
Identities = 22/92 (23%), Positives = 48/92 (52%), Gaps = 16/92 (17%)
Query: 130 LNRLEKTKVERFPDLAAEKECRDREERNEKK--AQIQEMKKREKEEM------------- 174
L++L+K K E++ L EK+ + +E+ + A ++E + REK+EM
Sbjct: 730 LDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEE-QLREKQEMIQLLRRGEVQWVE 788
Query: 175 KKKREMDELRSYSSLMKVENMSSNQDGNDSDE 206
++KR+++ +R +K ++DG + ++
Sbjct: 789 EEKRDLEGIRESLLRVKEARAGGDEDGEELEK 820
Score = 27.3 bits (59), Expect = 9.4
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 6/69 (8%)
Query: 111 FHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDRE-ERNEKKAQIQEMKKR 169
F RQ+ ++ +E K I EK K ++ AE E +E E K+ +I +++ R
Sbjct: 598 FERQQREELEKLESKRKLIEEMEEKQKSDK-----AELERMQQEVETQRKETEIVQLQIR 652
Query: 170 EKEEMKKKR 178
++EE K+R
Sbjct: 653 KQEESLKRR 661
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 37.0 bits (84), Expect = 0.012
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE 172
++K+ K E K R ++ K +R + EKE RE + +K+ + + KKRE+
Sbjct: 116 KKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN 175
Query: 173 --EMKKKREMDELRSYSSLMKVENMSSNQDGND 203
E KK+RE E R K E + D
Sbjct: 176 RKERKKERERKERRERKKERKKERRKKKERKKD 208
Score = 32.3 bits (72), Expect = 0.29
Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 113 RQKDVKIVTVEKKVNEILNR---LEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKR 169
R+K+ + EKK E R K K ER K+ R+R+ + +K + ++ +KR
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
Query: 170 EKEEMKKKRE 179
EKE K++R+
Sbjct: 150 EKERGKRERK 159
Score = 30.8 bits (68), Expect = 0.85
Identities = 24/106 (22%), Positives = 51/106 (48%), Gaps = 1/106 (0%)
Query: 74 LVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRL 133
+VKA S + N + S++ K + R++ K +K +
Sbjct: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGK 60
Query: 134 EKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKRE 179
++ K + + E+E R R+ER +++ + +E ++R++++ KKKRE
Sbjct: 61 KEKKKRKKRERGKERE-RKRKEREKQRKERREKERRKRKKEKKKRE 105
Score = 30.0 bits (66), Expect = 1.5
Identities = 15/52 (28%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Query: 134 EKTKVERFPDLAAEKECRDREERNEK-KAQIQEMKKREKEEMKKKREMDELR 184
EK K ER + E+ +++++R ++ + + +E K++E+E+ +K+R E R
Sbjct: 44 EKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95
Score = 28.1 bits (61), Expect = 5.5
Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQ-EMKKREK 171
R++ K +K+ E E+ K ER ++E + ERN K+ + + E K+R +
Sbjct: 131 RERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
Query: 172 EEMKKKREMDELRSYSSLMKVENMSSNQ 199
+ ++K+E + + K + + +Q
Sbjct: 191 RKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 27.7 bits (60), Expect = 7.2
Identities = 13/52 (25%), Positives = 28/52 (53%)
Query: 131 NRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDE 182
+ + K +R + E+ R++ +R +K + +E K+EK++ KK+ E
Sbjct: 23 SHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKE 74
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 37.0 bits (84), Expect = 0.012
Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 6/84 (7%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDE 182
+KK E E+T+ E EKE + +E+R EK+ + ++ KK ++ E +K++E +E
Sbjct: 6 KKKETEETEETEETEEEE------EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59
Query: 183 LRSYSSLMKVENMSSNQDGNDSDE 206
+ K + ++ + +E
Sbjct: 60 KKRKRKRKKKKEEEEREEEEEEEE 83
Score = 33.9 bits (76), Expect = 0.10
Identities = 18/62 (29%), Positives = 33/62 (53%)
Query: 121 TVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREM 180
T E + E E + E+ + EKE + + + EK+ + +E +K+ K + KKK+E
Sbjct: 13 TEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEE 72
Query: 181 DE 182
+E
Sbjct: 73 EE 74
Score = 32.7 bits (73), Expect = 0.22
Identities = 16/57 (28%), Positives = 35/57 (61%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKRE 179
E+K + + +K + ER + E+E ++ EE+ E + + ++ K+R KEE ++K++
Sbjct: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Score = 32.3 bits (72), Expect = 0.29
Identities = 16/45 (35%), Positives = 26/45 (57%)
Query: 134 EKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKR 178
E+ + E + EKE ++EE +K + + +K E+EE KKKR
Sbjct: 72 EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116
Score = 31.6 bits (70), Expect = 0.50
Identities = 18/62 (29%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDE 182
+KK E R EK + E+ +K+ ++ EER E++ + +E K+ E++E ++R+ +
Sbjct: 43 KKKTKETEKRKEKEEEEKKRKRKRKKK-KEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK 101
Query: 183 LR 184
R
Sbjct: 102 KR 103
Score = 30.8 bits (68), Expect = 0.85
Identities = 13/49 (26%), Positives = 29/49 (59%)
Query: 134 EKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDE 182
+K K + + +E + EE+ K+ + ++ K++EKE+ KK +E ++
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK 51
Score = 30.8 bits (68), Expect = 0.85
Identities = 16/70 (22%), Positives = 36/70 (51%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKE 172
++K K EK+ + ++ + + E+E + EE EK+ + +E +R K+
Sbjct: 40 KEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK 99
Query: 173 EMKKKREMDE 182
+ K++R+ +E
Sbjct: 100 KKKRRRKEEE 109
Score = 30.0 bits (66), Expect = 1.5
Identities = 13/48 (27%), Positives = 28/48 (58%)
Query: 135 KTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDE 182
K K ++ + +E + EE EK+ + +E +K +++E +KK++ E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKE 48
Score = 29.3 bits (64), Expect = 2.5
Identities = 16/51 (31%), Positives = 28/51 (54%)
Query: 134 EKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELR 184
+K K ++ + E E + EE E K + + +KR+++E KKK + E R
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKR 52
Score = 27.7 bits (60), Expect = 7.2
Identities = 17/69 (24%), Positives = 35/69 (50%)
Query: 114 QKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEE 173
+K+ K K+ + + +KTK E+E + + +R +KK + + ++ E+EE
Sbjct: 24 EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEE 83
Query: 174 MKKKREMDE 182
+K+ E E
Sbjct: 84 EEKEEEEKE 92
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 37.0 bits (84), Expect = 0.012
Identities = 25/84 (29%), Positives = 46/84 (54%), Gaps = 9/84 (10%)
Query: 124 KKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQ-EMKKREKEEMKKKREMDE 182
+++ I +EK + R E E R R+E E++ +++ E K++++EE +KKRE DE
Sbjct: 924 ERLRRIQEEMEKERKRR-----EEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDE 978
Query: 183 LRSYSSLMKVENMSSNQDGNDSDE 206
R + +VE + Q +S +
Sbjct: 979 KRIQA---EVEAQLARQKEEESQQ 999
Score = 29.6 bits (65), Expect = 1.9
Identities = 14/61 (22%), Positives = 33/61 (54%)
Query: 124 KKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDEL 183
K E+L+ L+K K + + + E+ +++ + ++ +++E+EE + K EM+
Sbjct: 904 KSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAK 963
Query: 184 R 184
R
Sbjct: 964 R 964
Score = 27.3 bits (59), Expect = 9.4
Identities = 13/60 (21%), Positives = 32/60 (53%)
Query: 123 EKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDE 182
++++ + + L K+ E L +K+ + ER + + E +++ +EE +K+R +E
Sbjct: 892 QEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEE 951
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 36.6 bits (83), Expect = 0.016
Identities = 31/125 (24%), Positives = 71/125 (56%), Gaps = 7/125 (5%)
Query: 84 KMNNVNVVYTPWSNLKKTADMDVGQIGFHR--QKDVKIVTVEKKVNEILNRLEKTKVERF 141
K+ N+ + S +K+T + ++ QI + + + V+V++ + E +N+L + K E+F
Sbjct: 785 KLTNLQENLSEVSQVKETLEKEL-QILKEKFAEASEEAVSVQRSMQETVNKLHQ-KEEQF 842
Query: 142 PDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELRSYSSLMKVENMSSNQDG 201
L+++ E + RE + +A+ +E +RE++ +K K +++ + +MK+ +S+Q
Sbjct: 843 NMLSSDLE-KLRENLADMEAKFREKDEREEQLIKAKEKLE--NDIAEIMKMSGDNSSQLT 899
Query: 202 NDSDE 206
+DE
Sbjct: 900 KMNDE 904
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 36.6 bits (83), Expect = 0.016
Identities = 31/125 (24%), Positives = 71/125 (56%), Gaps = 7/125 (5%)
Query: 84 KMNNVNVVYTPWSNLKKTADMDVGQIGFHR--QKDVKIVTVEKKVNEILNRLEKTKVERF 141
K+ N+ + S +K+T + ++ QI + + + V+V++ + E +N+L + K E+F
Sbjct: 820 KLTNLQENLSEVSQVKETLEKEL-QILKEKFAEASEEAVSVQRSMQETVNKLHQ-KEEQF 877
Query: 142 PDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELRSYSSLMKVENMSSNQDG 201
L+++ E + RE + +A+ +E +RE++ +K K +++ + +MK+ +S+Q
Sbjct: 878 NMLSSDLE-KLRENLADMEAKFREKDEREEQLIKAKEKLE--NDIAEIMKMSGDNSSQLT 934
Query: 202 NDSDE 206
+DE
Sbjct: 935 KMNDE 939
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 36.6 bits (83), Expect = 0.016
Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 10/101 (9%)
Query: 113 RQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREE--------RNEKKAQIQ 164
RQ D +I +EK+ + + RLE+ R D A + +E +N KK I
Sbjct: 872 RQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVIN 931
Query: 165 EMKKREKEEMKK--KREMDELRSYSSLMKVENMSSNQDGND 203
E++K KE K+ KR +EL + E + Q D
Sbjct: 932 EVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQQQELD 972
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,219,087
Number of Sequences: 37866
Number of extensions: 326123
Number of successful extensions: 6731
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 280
Number of HSP's successfully gapped in prelim test: 397
Number of HSP's that attempted gapping in prelim test: 3117
Number of HSP's gapped (non-prelim): 2777
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.