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Search of human proteins with 4557669
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557669 interleukin 4 receptor alpha chain isoform a
precursor [Homo sapiens]
(825 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557669 interleukin 4 receptor alpha chain isoform a precurso... 1736 0.0
gi|56788411 interleukin 4 receptor alpha chain isoform b precurs... 481 e-135
gi|4559408 colony stimulating factor 2 receptor, beta precursor ... 70 8e-12
gi|31083174 interleukin 21 receptor precursor [Homo sapiens] 53 1e-06
gi|11141869 interleukin 21 receptor precursor [Homo sapiens] 53 1e-06
gi|31083180 interleukin 21 receptor precursor [Homo sapiens] 53 1e-06
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 50 9e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 50 1e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 50 1e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 47 7e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 47 7e-05
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 46 2e-04
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 45 3e-04
gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 44 5e-04
gi|153792074 proline rich 12 [Homo sapiens] 44 5e-04
gi|221139926 NHS-like 1 [Homo sapiens] 44 6e-04
gi|238859557 regulatory factor X1 [Homo sapiens] 44 8e-04
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 44 8e-04
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 43 0.001
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 43 0.001
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 43 0.001
gi|163965366 nascent polypeptide-associated complex alpha subuni... 43 0.001
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 42 0.002
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 42 0.002
gi|150170670 piccolo isoform 2 [Homo sapiens] 42 0.003
gi|150378539 piccolo isoform 1 [Homo sapiens] 42 0.003
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca... 41 0.005
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca... 41 0.005
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca... 41 0.005
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal... 41 0.005
>gi|4557669 interleukin 4 receptor alpha chain isoform a precursor
[Homo sapiens]
Length = 825
Score = 1736 bits (4496), Expect = 0.0
Identities = 825/825 (100%), Positives = 825/825 (100%)
Query: 1 MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL 60
MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL
Sbjct: 1 MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL 60
Query: 61 LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH 120
LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH
Sbjct: 61 LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH 120
Query: 121 VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL 180
VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL
Sbjct: 121 VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL 180
Query: 181 EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQHLLLGVSVS 240
EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQHLLLGVSVS
Sbjct: 181 EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQHLLLGVSVS 240
Query: 241 CIVILAVCLLCYVSITKIKKEWWDQIPNPARSRLVAIIIQDAQGSQWEKRSRGQEPAKCP 300
CIVILAVCLLCYVSITKIKKEWWDQIPNPARSRLVAIIIQDAQGSQWEKRSRGQEPAKCP
Sbjct: 241 CIVILAVCLLCYVSITKIKKEWWDQIPNPARSRLVAIIIQDAQGSQWEKRSRGQEPAKCP 300
Query: 301 HWKNCLTKLLPCFLEHNMKRDEDPHKAAKEMPFQGSGKSAWCPVEISKTVLWPESISVVR 360
HWKNCLTKLLPCFLEHNMKRDEDPHKAAKEMPFQGSGKSAWCPVEISKTVLWPESISVVR
Sbjct: 301 HWKNCLTKLLPCFLEHNMKRDEDPHKAAKEMPFQGSGKSAWCPVEISKTVLWPESISVVR 360
Query: 361 CVELFEAPVECEEEEEVEEEKGSFCASPESSRDDFQEGREGIVARLTESLFLDLLGEENG 420
CVELFEAPVECEEEEEVEEEKGSFCASPESSRDDFQEGREGIVARLTESLFLDLLGEENG
Sbjct: 361 CVELFEAPVECEEEEEVEEEKGSFCASPESSRDDFQEGREGIVARLTESLFLDLLGEENG 420
Query: 421 GFCQQDMGESCLLPPSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPD 480
GFCQQDMGESCLLPPSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPD
Sbjct: 421 GFCQQDMGESCLLPPSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPD 480
Query: 481 NLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPT 540
NLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPT
Sbjct: 481 NLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPT 540
Query: 541 TVPQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGE 600
TVPQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGE
Sbjct: 541 TVPQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGE 600
Query: 601 AGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDRE 660
AGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDRE
Sbjct: 601 AGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDRE 660
Query: 661 PPRSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHL 720
PPRSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHL
Sbjct: 661 PPRSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHL 720
Query: 721 CGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASL 780
CGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASL
Sbjct: 721 CGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASL 780
Query: 781 APSGISEKSKSSSSFHPAPGNAQSSSQTPKIVNFVSVGPTYMRVS 825
APSGISEKSKSSSSFHPAPGNAQSSSQTPKIVNFVSVGPTYMRVS
Sbjct: 781 APSGISEKSKSSSSFHPAPGNAQSSSQTPKIVNFVSVGPTYMRVS 825
>gi|56788411 interleukin 4 receptor alpha chain isoform b precursor
[Homo sapiens]
Length = 227
Score = 481 bits (1237), Expect = e-135
Identities = 224/224 (100%), Positives = 224/224 (100%)
Query: 1 MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL 60
MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL
Sbjct: 1 MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL 60
Query: 61 LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH 120
LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH
Sbjct: 61 LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH 120
Query: 121 VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL 180
VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL
Sbjct: 121 VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL 180
Query: 181 EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNS 224
EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNS
Sbjct: 181 EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNS 224
>gi|4559408 colony stimulating factor 2 receptor, beta precursor
[Homo sapiens]
Length = 897
Score = 70.1 bits (170), Expect = 8e-12
Identities = 153/688 (22%), Positives = 238/688 (34%), Gaps = 143/688 (20%)
Query: 30 QEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCV---- 85
Q C D ++ +C W++ S L Y+ E C P G G +
Sbjct: 246 QNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEE-CSPVLREGLGSLHTRH 304
Query: 86 -CHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWS 144
C + + D + Y + + Q + K S +++ AP +L V T D+ L W
Sbjct: 305 HCQIPVPDPATHGQYIVSV---QPRRAEKHIKSSVNIQ-MAPPSLNV-TKDGDSYSLRWE 359
Query: 145 NPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISY--RARVR 202
Y H+ + I D A ++ L+ + +A L+ Y R RVR
Sbjct: 360 TM----KMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVR 415
Query: 203 AWAQCYNTTWSEWSPSTKWHNSYREPFEQHLLLGVSVSCIVILAVCLLCYVSITKIKKEW 262
YN WSEWS + W P L+ + ++ V+LA+ C + +++++W
Sbjct: 416 TSRTGYNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLAL-RFCGIYGYRLRRKW 474
Query: 263 WDQIPNPARSRLVAIIIQDAQGSQWEKRS-----RGQEPAKCPHWKNCLTKLLPCFLEHN 317
++IPNP++S L Q+ W S G P + P W + +L F
Sbjct: 475 EEKIPNPSKSHL----FQNGSAELWPPGSMSAFTSGSPPHQGP-WGSRFPELEGVFP--- 526
Query: 318 MKRDEDPHKAAKEMPFQGSGKSAWCP--VEISKTVLWPESISVVRCVELFEAPVECEEEE 375
G G S P +E K V P S + A + E+
Sbjct: 527 ----------------VGFGDSEVSPLTIEDPKHVCDPPS-----GPDTTPAASDLPTEQ 565
Query: 376 EVEEEKGSFCAS--PESSRDDFQEGREGIVARLTESLFLDLLGEENGGFCQQDMGESCLL 433
+ G AS PE F + + SL D+LG+ G S
Sbjct: 566 PPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSL-PDILGQPE----PPQEGGSQKS 620
Query: 434 PPSGSTSAHMPWDEFPSAGPKEAPP----WGKEQPLHLEPSPPASPTQSPDNLTCTETPL 489
PP GS + + P+ G + P G Q + +E P
Sbjct: 621 PPPGS----LEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQG--------------- 661
Query: 490 VIAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPET 549
AG+P+ S P P LG P + Q P +P +T
Sbjct: 662 -AAGSPSLES-----GGGPAPPALG-------------PRVGGQDQKDSPVAIPMSSGDT 702
Query: 550 WEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSL 609
+ G A+ VS+ + V G + S V LG P + SL
Sbjct: 703 EDP---------GVASGYVSS-----ADLVFTPNSGASSVSLVPSLGLPSD----QTPSL 744
Query: 610 LASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSH 669
A P SG EGY V +P ++ PRSP+++
Sbjct: 745 CPGLASGPPGAPGPVKSGFEGY----------------VELP----PIEGRSPRSPRNNP 784
Query: 670 LPSSSPEHLGLEPGEKVEDM-PKPPLPQ 696
+P + + L PGE+ D+ P P P+
Sbjct: 785 VPPEAKSPV-LNPGERPADVSPTSPQPE 811
Score = 31.2 bits (69), Expect = 4.1
Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 10/125 (8%)
Query: 29 LQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTC-IPENNGGAGCV-- 85
LQ C +DY S TC W + L+ ++ L E +C + ++ + C
Sbjct: 30 LQTLRCYNDYTSHITCRWADTQDAQRLVNVTLIRRVNEDLLEPVSCDLSDDMPWSACPHP 89
Query: 86 ------CHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTL 139
C + V D + L + + ++HV+P P +L + T+ D
Sbjct: 90 RCVPRRCVIPCQSFVVTDVDYFSFQPDRPLGTRLTVTLTQHVQPPEPRDLQISTD-QDHF 148
Query: 140 LLTWS 144
LLTWS
Sbjct: 149 LLTWS 153
>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 53.1 bits (126), Expect = 1e-06
Identities = 63/254 (24%), Positives = 104/254 (40%), Gaps = 19/254 (7%)
Query: 34 CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCI----PENNGGAGCVCHLL 89
C +DY+ C +M + L Q L EA +C N A CH+
Sbjct: 25 CYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMD 84
Query: 90 MDDVVSADNYTLDLW--AGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPY 147
+ ++ D +++++ +G GSF +E +KP P N+TV S ++W + Y
Sbjct: 85 VFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQYNISWRSDY 142
Query: 148 --PPDNYLYNHLTYAVNIWSENDP--ADFRIYNVTYLEPSLRIAASTLKSGISYRARVRA 203
P L L Y + + DP R ++ S+ + + SY +VRA
Sbjct: 143 EDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRA 202
Query: 204 W---AQCYNTTWSEWSPSTKWH---NSYREPFEQHLLLGVSVSCIVILAVCLLCYVSITK 257
Y TWSEWS + +E + HLLL + + + I A L + +
Sbjct: 203 GPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWR 262
Query: 258 IKKEWWDQIPNPAR 271
+ K+ W +P+P R
Sbjct: 263 LWKKIW-AVPSPER 275
>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 53.1 bits (126), Expect = 1e-06
Identities = 63/254 (24%), Positives = 104/254 (40%), Gaps = 19/254 (7%)
Query: 34 CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCI----PENNGGAGCVCHLL 89
C +DY+ C +M + L Q L EA +C N A CH+
Sbjct: 25 CYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMD 84
Query: 90 MDDVVSADNYTLDLW--AGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPY 147
+ ++ D +++++ +G GSF +E +KP P N+TV S ++W + Y
Sbjct: 85 VFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQYNISWRSDY 142
Query: 148 --PPDNYLYNHLTYAVNIWSENDP--ADFRIYNVTYLEPSLRIAASTLKSGISYRARVRA 203
P L L Y + + DP R ++ S+ + + SY +VRA
Sbjct: 143 EDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRA 202
Query: 204 W---AQCYNTTWSEWSPSTKWH---NSYREPFEQHLLLGVSVSCIVILAVCLLCYVSITK 257
Y TWSEWS + +E + HLLL + + + I A L + +
Sbjct: 203 GPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWR 262
Query: 258 IKKEWWDQIPNPAR 271
+ K+ W +P+P R
Sbjct: 263 LWKKIW-AVPSPER 275
>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 53.1 bits (126), Expect = 1e-06
Identities = 63/254 (24%), Positives = 104/254 (40%), Gaps = 19/254 (7%)
Query: 34 CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCI----PENNGGAGCVCHLL 89
C +DY+ C +M + L Q L EA +C N A CH+
Sbjct: 25 CYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMD 84
Query: 90 MDDVVSADNYTLDLW--AGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPY 147
+ ++ D +++++ +G GSF +E +KP P N+TV S ++W + Y
Sbjct: 85 VFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQYNISWRSDY 142
Query: 148 --PPDNYLYNHLTYAVNIWSENDP--ADFRIYNVTYLEPSLRIAASTLKSGISYRARVRA 203
P L L Y + + DP R ++ S+ + + SY +VRA
Sbjct: 143 EDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRA 202
Query: 204 W---AQCYNTTWSEWSPSTKWH---NSYREPFEQHLLLGVSVSCIVILAVCLLCYVSITK 257
Y TWSEWS + +E + HLLL + + + I A L + +
Sbjct: 203 GPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWR 262
Query: 258 IKKEWWDQIPNPAR 271
+ K+ W +P+P R
Sbjct: 263 LWKKIW-AVPSPER 275
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 50.1 bits (118), Expect = 9e-06
Identities = 82/361 (22%), Positives = 121/361 (33%), Gaps = 61/361 (16%)
Query: 456 APPWGKEQPLHLEPSPPASPTQSPDNLTCTET--PLVIAGNPAYRS-FSNSLSQSPCPRE 512
AP W QP P+P A+P+ T + P++ A +P+ S + L + P
Sbjct: 523 APAW---QPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSP-- 577
Query: 513 LGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAPVSAPT 572
P+PL + ++P +P P+ VPQ ETW L A P A +
Sbjct: 578 --PEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPL-------FPAPRPFPAQS 628
Query: 573 SGYQEF-VHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGY 631
S F + + G A + P G + + + E G+S GE+
Sbjct: 629 SASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEE----GSSPGED-- 682
Query: 632 KPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDMPK 691
+ G P P+P PL + R S LP + + G P
Sbjct: 683 ---SSSLGGGPSRRGPLPCPLCS--------REGACSCLPLERGDAVAGWGGHPALGCPH 731
Query: 692 PPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGD- 750
PP S+L G L P P G
Sbjct: 732 PPEDD-----------------SSLRAER-GSLADLPMAPPASAPPEFLDPLMGAAAPQY 773
Query: 751 --RSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSSSQT 808
R PP P P P P P + + P PS ++ SS P PG++ ++T
Sbjct: 774 PGRGPPPAPP---PPPPPPRAPADPAASPD--PPSAVASPGSGLSSPGPKPGDSGYETET 828
Query: 809 P 809
P
Sbjct: 829 P 829
Score = 33.9 bits (76), Expect = 0.63
Identities = 91/372 (24%), Positives = 122/372 (32%), Gaps = 73/372 (19%)
Query: 435 PSGSTSAHMPW--DEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQ--------SPDNLTC 484
P A W + P P PP + QP LEP+PP + + +PD+
Sbjct: 1156 PGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAG 1215
Query: 485 TETPLVIAGNPAYRSFSNSLSQSPCPRELGPD-PLLARHL-------EEVEPEMPCVPQL 536
+T L G+P P P GP+ P L L E+++ + +
Sbjct: 1216 GDTALSGDGDP------------PKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLA 1263
Query: 537 SEPTTV-----PQPEPETWEQI-LRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQA- 589
P T+ P P WE + G A AP A G E E A
Sbjct: 1264 LPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAP 1323
Query: 590 SAVVGLGPPGEAGYKAFSSLLASS---AVSP----EKCGFGASSGEEGYKPFQDLIPGCP 642
A G PG A +++S+ A P K GA E+ + +
Sbjct: 1324 GAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFH 1383
Query: 643 GDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDP 702
GD V V LF D+E P ++ L +P +P P PP P AT
Sbjct: 1384 GD---VTVYLF----DQETP----TNELSVQAPPEGDTDPSTP----PAPPTPPHPATP- 1427
Query: 703 LVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCC--GCCCGDRSSPPTTPLR 760
G G + G ED P P C P P R
Sbjct: 1428 -----GDG-----FPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVSPALETPGPPAR 1477
Query: 761 APDPSPGGVPLE 772
APD P G P+E
Sbjct: 1478 APDARPAG-PVE 1488
Score = 30.4 bits (67), Expect = 7.0
Identities = 29/103 (28%), Positives = 42/103 (40%), Gaps = 8/103 (7%)
Query: 447 EFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYR-SFSNSLS 505
++P GP APP P P PA P SPD + +P +P + S +
Sbjct: 772 QYPGRGPPPAPP-----PPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYET 826
Query: 506 QSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPE 548
++P E G P EE P P+ +P P+P P+
Sbjct: 827 ETPFSPE-GAFPGGGAAEEEGVPRPRAPPEPPDP-GAPRPPPD 867
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 49.7 bits (117), Expect = 1e-05
Identities = 44/132 (33%), Positives = 50/132 (37%), Gaps = 18/132 (13%)
Query: 433 LPPSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPAS---------PTQSPDNLT 483
+PPS S M P P PP PL + PSPPAS P Q+P L
Sbjct: 737 VPPSPPASPPMSPSATP---PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793
Query: 484 CTET---PLVIAGNPAYRSFSNSLSQSPCPRELGPD---PLLARHLEEVEPEMPCVPQLS 537
P A P FS S S P P P+LA L +V P P P L
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853
Query: 538 EPTTVPQPEPET 549
P P P P+T
Sbjct: 854 APRRPPTPGPDT 865
Score = 48.1 bits (113), Expect = 3e-05
Identities = 108/426 (25%), Positives = 144/426 (33%), Gaps = 57/426 (13%)
Query: 429 ESCLLPPSGSTSAHM----PWDEFPSAGPK--------------EAPPWGKEQPLHLEPS 470
+S L PPS T P + PS P E PP PL PS
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS 574
Query: 471 PPASPTQSPDNLTCT---ETPLVIAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVE 527
P +P + T + P +A P S LS P P P LA +
Sbjct: 575 PLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP-PXLALPPLQAP 633
Query: 528 PEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQE--FVHAVEQG 585
P P P LS P P P+ N L AP S P S + F
Sbjct: 634 PSPPASPPLS-PLATPSPQAP--------NALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684
Query: 586 GTQASAVVGLGPPGEAG--YKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPG 643
+ ++ PP A + S AS +SP + P Q +P P
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ--VP--PS 740
Query: 644 DPAPVPVPLFTFGLDREPPR-SPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDP 702
PA P+ R PP + +P S P L + P K P P P AT P
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK----PPPQAPPALATPP 796
Query: 703 L--VDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTP-L 759
L + S + A PV+A+P SPP +P L
Sbjct: 797 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV----PPSPPASPTL 852
Query: 760 RAP--DPSPG-GVPLEASLCPASLAPSGISEKSKSSSSFHPAP---GNAQSSSQTPKIVN 813
+AP P+PG + +LAP S+S SS P G++ S++ TP+ +
Sbjct: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912
Query: 814 FVSVGP 819
GP
Sbjct: 913 GYDSGP 918
Score = 36.6 bits (83), Expect = 0.098
Identities = 88/366 (24%), Positives = 128/366 (34%), Gaps = 69/366 (18%)
Query: 449 PSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSP 508
P+ GP+++ E EPSP A S PA RS S+S +
Sbjct: 201 PTEGPRKSVSSASEHST-TEPSPAARRRPSAGGGL---------QRPASRSLSSSATPLS 250
Query: 509 CPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAPV 568
P GP P P P QP+P+ + + V AAP
Sbjct: 251 SPARSGPSA-------RGTPRAPAHPS--------QPKPKGLQALRPPQVTPPRKDAAPA 295
Query: 569 SAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGE 628
P S + GT+A V PP + A + L A+ SP
Sbjct: 296 LGPLSSSP--LATPSPSGTKARPV----PPPD---NAATPLPATLPPSP----------- 335
Query: 629 EGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVED 688
P +P P P+ P L T PP +P S PS + + P ++
Sbjct: 336 ----PLATPLPLAPPSPS-APPSLQTLP---SPPATPPSQAPPSMTTPPMQAPPS--LQT 385
Query: 689 MPKPPLPQEQATDPLVDSLGSGIVYSAL---TCHLCGHLKQCHGQEDGGQTPVMASPCCG 745
+P +P T P + + S + S+L T L+ H +P
Sbjct: 386 IPPIQVPHS-LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT--MSPRQTQASLT 442
Query: 746 CCCGDRSSPPTTP-LRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQS 804
S+PP +P L+AP P PL+ SL PA +S S S + HP +
Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA------VSPLS-SPLTIHPLQALSSL 495
Query: 805 SSQTPK 810
+S +P+
Sbjct: 496 ASHSPQ 501
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 49.7 bits (117), Expect = 1e-05
Identities = 90/384 (23%), Positives = 128/384 (33%), Gaps = 46/384 (11%)
Query: 429 ESCLLPPSGSTSAHMPWDEFPSAGPKEAPPW-GKEQPLHLEPSPPASPTQSPDNLTCTET 487
ES L PP S S P +E P + P+E+PP E P L P P ASP P E+
Sbjct: 500 ESPLSPPPES-SPFSPLEESPLSPPEESPPSPALETP--LSPPPEASPLSPP----FEES 552
Query: 488 PLVIAGNPAYRSFSNSLSQSPCPREL--GPDPLLARHLEEVEPEMPCVPQLSEPTTVPQP 545
PL SP P EL P P +R L E P P E P P
Sbjct: 553 PL-----------------SPPPEELPTSPPPEASR-LSPPPEESPMSPPPEESPMSPPP 594
Query: 546 EPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKA 605
E + L +P+S P + + + + PP E +
Sbjct: 595 EASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLS 654
Query: 606 FSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSP 665
+++ + PE+ E P P + + + P + P SP
Sbjct: 655 PLPVVSRLSPPPEESPLSPPPEESPTSP--------PPEASRLSPP------PEDSPTSP 700
Query: 666 QSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLK 725
P+S P L +E+ P PLP+E P S G + HL +
Sbjct: 701 PPEDSPASPPPEDSL-MSLPLEESPLLPLPEEPQLCP--RSEGPHLSPRPEEPHLSPRPE 757
Query: 726 QCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGI 785
+ H + + P C C P +P +A P P E L P + P
Sbjct: 758 EPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP-QAEGPHLSPQPEELHLSPQTEEPHLS 816
Query: 786 SEKSKSSSSFHPAPGNAQSSSQTP 809
+ S P + S+ P
Sbjct: 817 PVPEEPCLSPQPEESHLSPQSEEP 840
Score = 48.9 bits (115), Expect = 2e-05
Identities = 103/403 (25%), Positives = 135/403 (33%), Gaps = 52/403 (12%)
Query: 429 ESCLLPPSGSTSAHMPWDEFPSAGPKEA---PPWGKEQP-------LHLEPSPPASPTQS 478
E LLPP + P +E P++ P EA P +E P LHL SP
Sbjct: 437 EMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSP 496
Query: 479 PDNLTCTETPLVIAGNPAYRSFSNSLSQSPC--PRELGPDPLLARHLE---EVEP----- 528
P E+PL P S + L +SP P E P P L L E P
Sbjct: 497 PPE----ESPL---SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF 549
Query: 529 -EMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGT 587
E P P E T P PE + + +P+S P + F E +
Sbjct: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLS 609
Query: 588 QASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAP 647
L PP EA + + PE E P P +P
Sbjct: 610 PPPEESPLSPPPEA---------SRLSPPPEDSPMSPPPEESPMSP-----PPEVSRLSP 655
Query: 648 VPVPLFTFGLDREPPRSPQSSHLPSS-SPEHLGLEPGEKVEDMPKPPLPQEQ-ATDPLVD 705
+PV E P SP P+S PE L P ED P P P++ A+ P D
Sbjct: 656 LPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSP--PPEDSPTSPPPEDSPASPPPED 713
Query: 706 SLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDPS 765
SL S + + L + C E +P P R P +A +P
Sbjct: 714 SLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEP----HLSPRPEEPHLSPQAEEPH 769
Query: 766 PGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSSSQT 808
P E LC P +S +++ P P S QT
Sbjct: 770 LSPQPEEPCLCAVPEEPH-LSPQAE-GPHLSPQPEELHLSPQT 810
Score = 47.8 bits (112), Expect = 4e-05
Identities = 77/297 (25%), Positives = 96/297 (32%), Gaps = 51/297 (17%)
Query: 430 SCLLPPSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPL 489
S L PP + P +E P++ P EA L P P SPT P + P
Sbjct: 660 SRLSPPPEESPLSPPPEESPTSPPPEAS--------RLSPPPEDSPTSPPPEDSPASPP- 710
Query: 490 VIAGNPAYRSFSNSLSQSP----------CPRELGPDPLLARHLEEVE----PEMPCV-P 534
P S L +SP CPR GP L+ EE PE P + P
Sbjct: 711 -----PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPH--LSPRPEEPHLSPRPEEPHLSP 763
Query: 535 QLSEPTTVPQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVG 594
Q EP PQPE + L A +S E +
Sbjct: 764 QAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPC 823
Query: 595 LGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGD-PAPVPVPLF 653
L P E + + S + PE+ + P + P PG PAP +PLF
Sbjct: 824 LSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF 883
Query: 654 ---------------TFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLP 695
EPP SP LP S L P + MP PLP
Sbjct: 884 PPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP----QLMPPDPLP 936
Score = 45.8 bits (107), Expect = 2e-04
Identities = 118/450 (26%), Positives = 151/450 (33%), Gaps = 108/450 (24%)
Query: 435 PSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGN 494
P G A+ FP+A P PP+ PSP +P Q P L + P AG
Sbjct: 2176 PFGLAPAYPLEPRFPTA-PPTYPPY---------PSPTGAPAQPP-MLGASSRPG--AGQ 2222
Query: 495 PAYRSFSNSLSQSPCPRELGPDPLLARHLEEVE----PEMPCVP--QLSEPTTVPQPEPE 548
P F + +P + PDP L ++ PE P V + SEP P P E
Sbjct: 2223 PG--EFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE 2280
Query: 549 TWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSS 608
+ + L + GA++ P G FV + G + + GL +KA +
Sbjct: 2281 S-RKALEVKKEELGASSPSYGPPNLG---FVDSPSSG----THLGGLELKTPDVFKAPLT 2332
Query: 609 LLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDP-----------------APVPVP 651
AS V P+ G G E P Q L P P P P P P
Sbjct: 2333 PRASQ-VEPQSPGLGLRPQEP--PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP 2389
Query: 652 LFTFGLDREPPRS---------PQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDP 702
PPRS P S SSS L P P P P+ Q+ DP
Sbjct: 2390 PPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDP 2449
Query: 703 LV-----------------------------------DSLGSGIVYSALTCHLCGHLKQC 727
SLG+G +AL G L
Sbjct: 2450 YSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGEL--- 2506
Query: 728 HGQEDGGQTP-VMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGIS 786
H + GQ P + SP G G S P+R P G P SL P P G+
Sbjct: 2507 HAKVPSGQPPNFVRSPGTGAFVGTPS-----PMRFTFPQAVGEP---SLKPPVPQP-GLP 2557
Query: 787 EKSKSSSSFHPAP--GNAQSSSQTPKIVNF 814
+S F P P G QS++ T NF
Sbjct: 2558 PPHGINSHFGPGPTLGKPQSTNYTVATGNF 2587
Score = 35.0 bits (79), Expect = 0.28
Identities = 67/265 (25%), Positives = 87/265 (32%), Gaps = 54/265 (20%)
Query: 462 EQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPDPLLAR 521
+ PL P PP P C P + +P R ++ SQS L P PL A
Sbjct: 2380 QPPLTPRPQPP------PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAE 2433
Query: 522 HL--EEVEPEMPCVPQLSEPTTVPQ-----------PEPETWEQILRRNVLQH---GAAA 565
V P S P + PQ P P+ E + L H GA
Sbjct: 2434 AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGG 2493
Query: 566 APVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGAS 625
P + P E +HA G + V G G SP + F +
Sbjct: 2494 FPAALPAGPAGE-LHAKVPSGQPPNFVRSPGTGAFVG-----------TPSPMRFTFPQA 2541
Query: 626 SGEEGYKPFQDLIPGCPGDPAPVPV-----PLFTFGLDREPPRSPQSSHL-PSSSP---- 675
GE KP +P PG P P + P T G + + + + PS SP
Sbjct: 2542 VGEPSLKP---PVPQ-PGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPS 2597
Query: 676 -----EHLGLEPGEKVEDMPKPPLP 695
E GL P +P PP P
Sbjct: 2598 SGSTGESYGLSPLRPPSVLP-PPAP 2621
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 47.0 bits (110), Expect = 7e-05
Identities = 41/135 (30%), Positives = 48/135 (35%), Gaps = 34/135 (25%)
Query: 449 PSAGP-KEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGN------------- 494
PSA P +APP PL + PSPPASP SP + P +A
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521
Query: 495 -----------------PAYRSFSNSLSQSPCPRELGP---DPLLARHLEEVEPEMPCVP 534
P FS S S P P P+LA L +V P P P
Sbjct: 522 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 581
Query: 535 QLSEPTTVPQPEPET 549
L P P P P+T
Sbjct: 582 TLQAPRRPPTPGPDT 596
Score = 46.2 bits (108), Expect = 1e-04
Identities = 88/363 (24%), Positives = 111/363 (30%), Gaps = 50/363 (13%)
Query: 453 PKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIA------------GNPAYRSF 500
P +APP PL PSPPASP SP + P +A P F
Sbjct: 393 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 452
Query: 501 SNSLSQSPCPRELGPD---PLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRN 557
S S P P P LA +V P P P +S T P P L
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP----LAAP 508
Query: 558 VLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSP 617
LQ A P AP A+ QA PG+A + +SL S +P
Sbjct: 509 PLQ--LAKPPPQAPP--------ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
Query: 618 EKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEH 677
+ P + P P P T R PP +P S
Sbjct: 559 PPQAPPVLAA-----PLLQVPPSPPASP--------TLQAPRRPP-TPGPDTSVSGPRLT 604
Query: 678 LGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTP 737
L L PG P PP +T D G ++ L G+ G P
Sbjct: 605 LALAPGP-----PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 659
Query: 738 VMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHP 797
C R P R +P +P + P S +++ S P
Sbjct: 660 DAELAACHPAAWSRGPAPPLAFRGAPGAP--LPWPPATGPGSADGLCTIYETEGPESATP 717
Query: 798 APG 800
APG
Sbjct: 718 APG 720
Score = 38.9 bits (89), Expect = 0.020
Identities = 79/376 (21%), Positives = 114/376 (30%), Gaps = 93/376 (24%)
Query: 438 STSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAY 497
S S H + P+A + + G ++P S A+P SP P+
Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR-----------SGPSA 259
Query: 498 RSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQL----SEPTTVPQPEPETWEQI 553
R + + P+ G L R + P P L S P P P Q
Sbjct: 260 RGTPRAPAHPSQPKPKGLQAL--RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ- 316
Query: 554 LRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASS 613
AP + P + + + Q + + L PP + + +L +
Sbjct: 317 ------------APPTLPATPHSSSLTC------QLATPLPLAPPSPSAPPSLQTLPSPP 358
Query: 614 AVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSS 673
A P + S G + +P P P P P L P ++P S P +
Sbjct: 359 ATPPSQAT--TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS---PPA 413
Query: 674 SPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDG 733
SP P PL P +AL HL
Sbjct: 414 SP--------------PLSPLATPSPQAP-----------NALAVHLL------------ 436
Query: 734 GQTPVMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSS 793
Q P S PP+ P++AP P P+ S P S AP ++
Sbjct: 437 -QAPF-------------SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 482
Query: 794 SFHPAPGNAQSSSQTP 809
PA S S TP
Sbjct: 483 PSPPA-SPPMSPSATP 497
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 47.0 bits (110), Expect = 7e-05
Identities = 41/135 (30%), Positives = 48/135 (35%), Gaps = 34/135 (25%)
Query: 449 PSAGP-KEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGN------------- 494
PSA P +APP PL + PSPPASP SP + P +A
Sbjct: 423 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482
Query: 495 -----------------PAYRSFSNSLSQSPCPRELGP---DPLLARHLEEVEPEMPCVP 534
P FS S S P P P+LA L +V P P P
Sbjct: 483 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 542
Query: 535 QLSEPTTVPQPEPET 549
L P P P P+T
Sbjct: 543 TLQAPRRPPTPGPDT 557
Score = 46.2 bits (108), Expect = 1e-04
Identities = 88/363 (24%), Positives = 111/363 (30%), Gaps = 50/363 (13%)
Query: 453 PKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIA------------GNPAYRSF 500
P +APP PL PSPPASP SP + P +A P F
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 413
Query: 501 SNSLSQSPCPRELGPD---PLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRN 557
S S P P P LA +V P P P +S T P P L
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP----LAAP 469
Query: 558 VLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSP 617
LQ A P AP A+ QA PG+A + +SL S +P
Sbjct: 470 PLQ--LAKPPPQAPP--------ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519
Query: 618 EKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEH 677
+ P + P P P T R PP +P S
Sbjct: 520 PPQAPPVLAA-----PLLQVPPSPPASP--------TLQAPRRPP-TPGPDTSVSGPRLT 565
Query: 678 LGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTP 737
L L PG P PP +T D G ++ L G+ G P
Sbjct: 566 LALAPGP-----PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 620
Query: 738 VMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHP 797
C R P R +P +P + P S +++ S P
Sbjct: 621 DAELAACHPAAWSRGPAPPLAFRGAPGAP--LPWPPATGPGSADGLCTIYETEGPESATP 678
Query: 798 APG 800
APG
Sbjct: 679 APG 681
Score = 36.6 bits (83), Expect = 0.098
Identities = 79/361 (21%), Positives = 108/361 (29%), Gaps = 94/361 (26%)
Query: 449 PSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSP 508
P+ GP+++ E EPSP A S PA RS S+S +
Sbjct: 192 PTEGPRKSVSSASEHST-TEPSPAARRRPSAGGGL---------QRPASRSLSSSATPLS 241
Query: 509 CPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAPV 568
P GP P P P QP+P+ + + V AAP
Sbjct: 242 SPARSGPSA-------RGTPRAPAHPS--------QPKPKGLQALRPPQVTPPRKDAAPA 286
Query: 569 SAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGE 628
P S + + PP + + +L + A P + S G
Sbjct: 287 LGPLSS------------SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT--TSLGS 332
Query: 629 EGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVED 688
+ +P P P P P L P ++P S P +SP
Sbjct: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS---PPASP------------- 376
Query: 689 MPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCC 748
P PL P +AL HL Q P
Sbjct: 377 -PLSPLATPSPQAP-----------NALAVHLL-------------QAPF---------- 401
Query: 749 GDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSSSQT 808
S PP+ P++AP P P+ S P S AP ++ PA S S T
Sbjct: 402 ---SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA-SPPMSPSAT 457
Query: 809 P 809
P
Sbjct: 458 P 458
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 45.8 bits (107), Expect = 2e-04
Identities = 85/367 (23%), Positives = 114/367 (31%), Gaps = 59/367 (16%)
Query: 463 QPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPDPLLARH 522
Q + L PS A +PD L TP G A Q+P P P PL +
Sbjct: 584 QGVTLPPSAVAM-LNTPDGLVQPATPAAATGEAAPVLTVQPAPQAP-PAVSTPLPLGLQQ 641
Query: 523 LEEVEPEMPCVPQLSEP--TTVPQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVH 580
+ +P PQ + P T PQP P + VL +A P + T +
Sbjct: 642 PQAQQPPQAPTPQAAAPPQATTPQPSPGLASSP-EKIVLGQPPSATPTAILTQDSLQMFL 700
Query: 581 AVEQG-----------GTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEE 629
E+ AS +V PP + A + + G G + +
Sbjct: 701 PQERSQQPLSAEGPHLSVPASVIVSAPPPAQDP--------APATPVAKGAGLGPQAPDS 752
Query: 630 GYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQ-----SSHLPSSSPEHLGLEPGE 684
P P P PL G P Q S HLPS P P
Sbjct: 753 QASP-------APAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPS 805
Query: 685 KVEDMPKPPL--PQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASP 742
+ + + +PP P P GI Q G P ++P
Sbjct: 806 RPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVI---------------QNQLGVPPPASNP 850
Query: 743 CCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNA 802
PP PLR P G A P S S ++ S++SS PAP +
Sbjct: 851 A-----PTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRL-PAPTPS 904
Query: 803 QSSSQTP 809
Q P
Sbjct: 905 DFQLQFP 911
Score = 40.8 bits (94), Expect = 0.005
Identities = 66/268 (24%), Positives = 91/268 (33%), Gaps = 56/268 (20%)
Query: 449 PSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSP 508
P++ P P + PL + PP P +L + T +A S S + S+ P
Sbjct: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVA------SSSETSSRLP 899
Query: 509 CPR----ELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAA 564
P +L P H P P + + EP P P P T++ +
Sbjct: 900 APTPSDFQLQFPPSQGPHKSPTPP--PTLHLVPEPAAPPPPPPRTFQMV---------TT 948
Query: 565 AAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGA 624
P E H V G ++ G A +S SP A
Sbjct: 949 PFPALPQPKALLERFHQVPSG------IILQNKAGGAPAAPQTSTSLGPLTSP-----AA 997
Query: 625 SSGEEGYKPFQDLIPGCPGDP--APVPVPLFTFGLDREPPRSPQ-----SSHLP------ 671
S G P G P P AP P P+ GL PP P +S+LP
Sbjct: 998 SVLVSGQAP-----SGTPTAPSHAPAPAPMAATGL---PPLLPAENKAFASNLPTLNVAK 1049
Query: 672 --SSSP-EHLGLEPGEKVEDMPKPPLPQ 696
SS P + GL+ K+ + KPP Q
Sbjct: 1050 AASSGPGKPSGLQYESKLSGLKKPPTLQ 1077
Score = 32.7 bits (73), Expect = 1.4
Identities = 90/377 (23%), Positives = 121/377 (32%), Gaps = 66/377 (17%)
Query: 449 PSAGPKEAPPWGKEQPLHLE-PSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQS 507
P+ P A P K L + P ASP +P PL G + S +
Sbjct: 729 PAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQ--IPAAAPLKGPGPSSSPSLPHQAPLG 786
Query: 508 PCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAP 567
P P P P+ P SEP P P P+ + V+Q+ P
Sbjct: 787 DSPHLPSPHPTRPPSRPPSRPQSVSRPP-SEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP 845
Query: 568 VSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSG 627
P S Q + + GP A + SS SSAV ASS
Sbjct: 846 ---PASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSS--TSSAV--------ASSS 892
Query: 628 EEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVE 687
E + PAP P F L P + P S P + HL EP
Sbjct: 893 ETSSRL-----------PAPTPSD---FQLQFPPSQGPHKSPTPPPTL-HLVPEPAAPPP 937
Query: 688 DMPK---------PPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPV 738
P+ P LPQ +A + SGI+ + G QT
Sbjct: 938 PPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQ----------NKAGGAPAAPQTST 987
Query: 739 ----MASPCCGCCCGDR--SSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSS 792
+ SP + S PT P AP P+P L PA ++K+
Sbjct: 988 SLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPA---------ENKAF 1038
Query: 793 SSFHPAPGNAQSSSQTP 809
+S P A+++S P
Sbjct: 1039 ASNLPTLNVAKAASSGP 1055
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 45.1 bits (105), Expect = 3e-04
Identities = 100/412 (24%), Positives = 134/412 (32%), Gaps = 90/412 (21%)
Query: 434 PPSGSTSAHMPWDEFPSAGPKE-----APPWGKEQPLHLEPSPPASPTQSPDNLTCTETP 488
PP S + H+P P G APP+ L P P L P
Sbjct: 288 PPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQ-GRRP 346
Query: 489 LVIAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPE-- 546
A S S+S S P R P + R LE P+ P + P VPQP
Sbjct: 347 RAQAP-----SASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSL 401
Query: 547 PETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAF 606
PE + IL +++GL PG +
Sbjct: 402 PEPSQPIL--------------------------------PSVLSLLGLPTPGPSHSDGS 429
Query: 607 SSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPG--------CPGDPAPVPVPLFTFGLD 658
+LL S A P + S + P Q +PG PG PA
Sbjct: 430 FNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPA------------ 477
Query: 659 REPPRSPQSSHLPS----SSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYS 714
PP + ++ +PS S E LG+ G P PPL +A S G+ S
Sbjct: 478 --PPAASKAPVVPSPVLQSPSEGLGMGAGPA---CPLPPLAGGEAFP--FPSPEQGLALS 530
Query: 715 -ALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDPSPG-----G 768
A + G L +P++ G G PP PL P PG G
Sbjct: 531 GAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPG 590
Query: 769 VPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSSSQTPKIVNFVSVGPT 820
P SL ASL P S+ P +A S+ + +++GPT
Sbjct: 591 EPEGPSLLVASLLPPPPSDLL--------PPPSAPPSNLLASFLPLLALGPT 634
>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
Length = 780
Score = 44.3 bits (103), Expect = 5e-04
Identities = 81/321 (25%), Positives = 112/321 (34%), Gaps = 61/321 (19%)
Query: 434 PPSGSTSAHM--PWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVI 491
PP G A P FP A P QP + + P T P N+T + + +
Sbjct: 279 PPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSL 338
Query: 492 -------AGNPAY---RSFSNSLSQSPCPREL------GPDPLLARHLEEVEPEMPCVPQ 535
G PA + F+ Q P P L G L +H+ ++P P P
Sbjct: 339 PPQPGPAVGAPAAQQPQQFAYPQPQIP-PGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPS 397
Query: 536 LSEPTTVP-----------QPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQ 584
+ P Q Q++ + Q A AP + P G Q V +
Sbjct: 398 STGAAASPATAATLPVGTGQNASSVGAQLMGAS-SQPSEAMAPRTGPAQGGQ--VAPCQP 454
Query: 585 GGTQASAVVGLGPP--GEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCP 642
G + V G+ P G AG + S P+ G G S G ++PG P
Sbjct: 455 TGVPPATVGGVVQPCLGPAG-----AGQPQSVPPPQMGGSGPLSAVPGGP--HAVVPGVP 507
Query: 643 GDPAPVPVP------LFTFGLDREPPRSPQSSHLPSSSP--------EHLG--LEPG--E 684
PA VP P + + P QS L S +P +H+G L PG
Sbjct: 508 NVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHS 567
Query: 685 KVEDMPKPPLPQEQA-TDPLV 704
+P+ L Q Q T PLV
Sbjct: 568 APTSLPQSDLSQFQTQTQPLV 588
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 44.3 bits (103), Expect = 5e-04
Identities = 47/187 (25%), Positives = 73/187 (39%), Gaps = 29/187 (15%)
Query: 452 GPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAG---NPAYRSFSNSLSQSP 508
GP + PP+ P +P PP + NL + + A +P +FS + P
Sbjct: 220 GPAQTPPYRPGPP---DPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPP 276
Query: 509 CP-RELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAP 567
P R L + +H + P ++P P P + LQH +
Sbjct: 277 PPERALPRQDTVIKHYQR--------PASAQPPPPPPPA----------HALQHYLSCGG 318
Query: 568 VSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGF-GASS 626
S P+ G++ + GG + S G G P +AG ++ + A PE G GA
Sbjct: 319 -SYPSMGHRANLACSPLGGGEPSP--GAGEPSKAGPSGATAGASGRATGPEAAGGGGAGG 375
Query: 627 GEEGYKP 633
G GY+P
Sbjct: 376 GGGGYRP 382
Score = 32.7 bits (73), Expect = 1.4
Identities = 70/315 (22%), Positives = 104/315 (33%), Gaps = 57/315 (18%)
Query: 433 LPPSGSTSAHMPWDEFPSAGPKEAP--PWGKEQPLHLEPSPPASPTQSPDNLTCTETPLV 490
L P+ + P PSA P P +E+P P+PP +PT P P
Sbjct: 1424 LAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKP---PPTPPPAPTPQPQPPPPPPPPQP 1480
Query: 491 IAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETW 550
+P SP P L P P A P P + P P PE
Sbjct: 1481 ALPSPP--PLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDP 1538
Query: 551 E----QILRRNVLQHGAAAAPVSAPTSG----------YQEFV-HAVEQGGTQASAVVGL 595
E + L Q AA + +G EFV A + + + G
Sbjct: 1539 ELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGR 1598
Query: 596 GPPGEAGYKAFSSLLA--SSAVSPEKCGFGASSGEEGY---------------------K 632
PP ++ +LL + + + F A+S GY K
Sbjct: 1599 EPP--PIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKK 1656
Query: 633 PFQDLIPGCPGDPAPVPV--------PLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGE 684
+ + P PVPV P+ G PP++P P + + +P E
Sbjct: 1657 DYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPE 1716
Query: 685 KVED--MPKPPLPQE 697
+ + MP+PP P++
Sbjct: 1717 QTPETAMPEPPAPEK 1731
Score = 31.6 bits (70), Expect = 3.1
Identities = 71/291 (24%), Positives = 97/291 (33%), Gaps = 64/291 (21%)
Query: 539 PTTVPQPEPETW--EQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQ----ASAV 592
P + + +P+ + + ++R + A A + +E E+GG A++V
Sbjct: 687 PYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSV 746
Query: 593 VGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPL 652
V G AG K + L S P G L G P P +P P
Sbjct: 747 VHYG----AGAKELGAFLQKSPPPPPPTAQSTQPTPHGLL----LEAGGPDLPLVLPPP- 797
Query: 653 FTFGLDREPPRSPQS--SHLPSSSPE------HLGLEPGEKVEDMPKPPLPQEQATDPLV 704
PP+ S SH PS SP HL LEP + + P+PP P P+
Sbjct: 798 --------PPQLLPSVLSHAPSPSPSASKVGVHL-LEPATR-DGAPQPPPPPPPPPPPM- 846
Query: 705 DSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDP 764
L HL+ HG E A+P SP P + DP
Sbjct: 847 ------------PLQLEAHLRS-HGLEP-------AAP----------SPRLRPEESLDP 876
Query: 765 SPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSSSQTPKIVNFV 815
L +L P AP +S PA S Q K FV
Sbjct: 877 PGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFV 927
Score = 30.8 bits (68), Expect = 5.4
Identities = 70/268 (26%), Positives = 90/268 (33%), Gaps = 63/268 (23%)
Query: 449 PSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSP 508
P + PK PP L+P PPA+P P L A A SP
Sbjct: 1306 PLSPPKSVPP--SVPARGLQPQPPATPAV-PHPPPSGAFGLGGALEAAESEGLGLGCPSP 1362
Query: 509 CPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAPV 568
C R D L R+LE T+P + + + + LQ ++A +
Sbjct: 1363 CKRL---DEELKRNLE----------------TLPSFSSDEEDSVAKNRDLQESISSA-I 1402
Query: 569 SA----PTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGA 624
SA P +G ++ + G A A GPP G + A+S +PE
Sbjct: 1403 SALDDPPLAGPKDT--STPDGPPLAPAAAVPGPPPLPGLPS-----ANSNGTPEP----- 1450
Query: 625 SSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPS---------SSP 675
P + P PAP P P PP P LPS SSP
Sbjct: 1451 --------PLLEEKPPPTPPPAPTPQP------QPPPPPPPPQPALPSPPPLVAPTPSSP 1496
Query: 676 EHLGLEPGEKVEDMPKPPLPQEQATDPL 703
L P MP PP P A PL
Sbjct: 1497 PPPPLPP-PPPPAMPSPPPPPPPAAAPL 1523
>gi|221139926 NHS-like 1 [Homo sapiens]
Length = 1606
Score = 43.9 bits (102), Expect = 6e-04
Identities = 99/433 (22%), Positives = 137/433 (31%), Gaps = 67/433 (15%)
Query: 389 ESSRDDFQEGREGIVARLTESLFLDLLGEENGGFCQQDMG--ESCLLPPSGSTSAHMPWD 446
+SS+ + Q E ++A L SL L L G+ Q E LP S S S
Sbjct: 687 KSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGS 746
Query: 447 EFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSP-----DNLTCTETPLVIAGNPAYRSFS 501
SA P + S S P D E P GNPA
Sbjct: 747 SMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDP----GNPA----G 798
Query: 502 NSLSQSPCPRELGPDPLLARHLEE-VEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQ 560
+ S P GP RH++E MP VP S + PE R +
Sbjct: 799 GCSTSSGVPTGNGP----VRHVQEGSRATMPQVPGGSVKPKIMSPEKS------HRVISP 848
Query: 561 HGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKC 620
++ + PT+ + V S G G P + SSL++S ++S
Sbjct: 849 SSGYSSQSNTPTA-----LTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSST 903
Query: 621 GFGASSGEEGYKPFQDLIPGCPGDPA----PVPVPLFTFGLDREPPRSPQSSHLPSSSPE 676
+S+ EG + L P PA PVP P F DR P P P
Sbjct: 904 SLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPP--------PPP 955
Query: 677 HLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQT 736
G + P P P +A P C C +
Sbjct: 956 VTDCSQGSPLPHSPVFPPPPPEALIP-----------------FCSPPDWCLSPPRPALS 998
Query: 737 PVMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFH 796
P++ PP P P P+P PL+ + P S + +SS
Sbjct: 999 PILPDSPVSL----PLPPPLLPSSEPPPAP---PLDPKFMKDTRPPFTNSGQPESSRGSL 1051
Query: 797 PAPGNAQSSSQTP 809
P + +S+ P
Sbjct: 1052 RPPSTKEETSRPP 1064
Score = 36.6 bits (83), Expect = 0.098
Identities = 90/392 (22%), Positives = 133/392 (33%), Gaps = 67/392 (17%)
Query: 431 CLLPPSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLV 490
CL PP + S +P + P + P PP PL PP +P P + T P
Sbjct: 989 CLSPPRPALSPILP--DSPVSLP--LPP-----PLLPSSEPPPAPPLDPKFMKDTRPPFT 1039
Query: 491 IAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETW 550
+G P S + P +E E P MP + +E + Q P
Sbjct: 1040 NSGQP---ESSRGSLRPPSTKE-----------ETSRPPMPLI--TTEALQMVQLRP--- 1080
Query: 551 EQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLL 610
+R+N GA AA +S T+ Q A + ++ + E ++ + +
Sbjct: 1081 ---VRKN---SGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASV 1134
Query: 611 ASSAVSPEKC---GFGASSGEEGYKPFQDLIPGCP------GDPAPVPVPLFTFGLDREP 661
SS +P K G S+ E G + PG P P+P PL R+P
Sbjct: 1135 TSSLPTPAKSSSQGDHGSAAERGGPVSRS--PGAPSAGEAEARPSPSTTPLPDSSPSRKP 1192
Query: 662 P---RSPQSSHLPSSSPEHLGLEPGEKVED----MPKPPLPQEQATDPLVDSLGSGIVYS 714
P + P+ + + +EP E V + +P P +E G V+S
Sbjct: 1193 PPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEE------------GSVHS 1240
Query: 715 ALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEAS 774
H G T V+ G R P+ PD SP E +
Sbjct: 1241 REAKESSAAQAGSHATHPG--TSVLEGGAAGSMSPSRVE-ANVPMVQPDVSPAPKQEEPA 1297
Query: 775 LCPASLAPSGISEKSKSSSSFHPAPGNAQSSS 806
A G S S+ + NA SS
Sbjct: 1298 ENSADTGGDGESCLSQQDGAAGVPETNAAGSS 1329
>gi|238859557 regulatory factor X1 [Homo sapiens]
Length = 979
Score = 43.5 bits (101), Expect = 8e-04
Identities = 35/106 (33%), Positives = 47/106 (44%), Gaps = 17/106 (16%)
Query: 449 PSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSP 508
P + P +APP + QP P PPA+P Q P T TP P Y + QSP
Sbjct: 14 PPSQPPQAPPQAQPQPP--PPPPPAAP-QPPQPPTAAATP-----QPQYVTEL----QSP 61
Query: 509 CPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQIL 554
P+ P ++ E+P VP S+PT P P P + I+
Sbjct: 62 QPQAQPPGGQ-----KQYVTELPAVPAPSQPTGAPTPSPAPQQYIV 102
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
sapiens]
Length = 2231
Score = 43.5 bits (101), Expect = 8e-04
Identities = 111/476 (23%), Positives = 160/476 (33%), Gaps = 84/476 (17%)
Query: 372 EEEEEVEEEKGSFCASPESSRDDFQEGREGIVARLTESLFLDLLGEENGGFCQQDMGESC 431
E+ +++E+ S S DD G TE+ + Q D
Sbjct: 594 EDLNLIQQERPSSLPDLSGSIDDLPTG--------TEATLSSAVSASGSTSSQGDQSNPA 645
Query: 432 LLPPSGSTSAHMPWDEFPSAGPKEAP---PWGKEQPLHLEPSPPASPTQSPDNLTCTETP 488
P S S H+ P GP +P P G Q S P SP P + + P
Sbjct: 646 QSPFSPHASPHL--SSIPG-GPSPSPVGSPVGSNQ----SRSGPISPASIPGSQMPPQPP 698
Query: 489 LVIAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCV-PQLSEPTTVPQPEP 547
G+ + S +LSQSP P+E G R+ P+M PQ + P+ P P P
Sbjct: 699 ----GSQSESSSHPALSQSPMPQERGFMAGTQRN-----PQMAQYGPQQTGPSMSPHPSP 749
Query: 548 --------ETWEQI------------------LRRNVLQHGAAAAPVSAPTSGY----QE 577
+++Q R G +A S P G
Sbjct: 750 GGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANN 809
Query: 578 FVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDL 637
+H QG +Q V LG AG + S+++P G G P +
Sbjct: 810 QMHG--QGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTV 867
Query: 638 IPGCPGDPAPVPVPLFTFGLDREP--PRSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLP 695
A V R+ P QS + SSSP + + + PP
Sbjct: 868 NRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYS 927
Query: 696 QEQA-TDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSP 754
A + S+G + S L LK G+E+G P S + S
Sbjct: 928 MAPAMVNSSAASVGLADMMSPGESKLPLPLK-ADGKEEGTPQPESKS---------KDSY 977
Query: 755 PTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSSSQTPK 810
+ + P P+PG +P+ PS +S S S SSFH ++ SS PK
Sbjct: 978 SSQGISQP-PTPGNLPV----------PSPMSPSSASISSFHGDESDSISSPGWPK 1022
Score = 33.5 bits (75), Expect = 0.83
Identities = 49/181 (27%), Positives = 64/181 (35%), Gaps = 36/181 (19%)
Query: 492 AGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCV----PQLSEPTTVPQPEP 547
A A F Q+ P G P L + L P M P+ S P+ P P
Sbjct: 336 AAGSAAGGFQRFAGQNQHPS--GATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPS 393
Query: 548 ETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFS 607
+ Q AAAA +A GG QA+A +GLG A Y A S
Sbjct: 394 QPQSQ----------AAAAGAAA--------------GGQQAAAGMGLGKDMGAQYAAAS 429
Query: 608 SLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQS 667
+ A + ++ S G G P G P DP + P +G+ P PQ
Sbjct: 430 ---PAWAAAQQRSHPAMSPGTPG--PTMGRSQGSPMDPMVMKRPQL-YGMGSNPHSQPQQ 483
Query: 668 S 668
S
Sbjct: 484 S 484
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 43.1 bits (100), Expect = 0.001
Identities = 66/294 (22%), Positives = 110/294 (37%), Gaps = 46/294 (15%)
Query: 435 PSG-STSAHMPWDEFPSAGPKEA-PPWGKEQPL---HLEPSPPASPTQSPDNLTCTETPL 489
PSG P+ S P++ PP+ ++ P H +PS P P L ++ P
Sbjct: 459 PSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPY 518
Query: 490 VIAGN-------PA-YRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTT 541
+ PA Y S ++ Q P + P ++ +P+ P LS+
Sbjct: 519 SQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAA 578
Query: 542 VPQPEPETWEQI------------LRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQA 589
PQP+ + +Q L ++ A++AP + G QE ++ Q +
Sbjct: 579 YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSS 638
Query: 590 ----SAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDP 645
S + P G G A S +++S +S + G ++ + + P P PG
Sbjct: 639 LPDLSGSIDDLPMGTEG--ALSPGVSTSGISSSQ-GEQSNPAQSPFSPHTS--PHLPGIR 693
Query: 646 APVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQA 699
P P P+ SP S S P PG ++ P+PP Q +
Sbjct: 694 GPSPSPV----------GSPASVAQSRSGPLSPAAVPGNQMP--PRPPSGQSDS 735
Score = 34.3 bits (77), Expect = 0.48
Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 14/117 (11%)
Query: 448 FPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQS 507
+PS G ++ PP+G P+ PP S Q P ++ P V + P R N S S
Sbjct: 1545 WPSHGTRQ-PPYGPSAPVPPMTRPPPSNYQPPPSMQ-NHIPQVSSPAPLPRPMENRTSPS 1602
Query: 508 PCP--------RELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRR 556
P ++ GP P+ A H+ P P P + T P E + +L++
Sbjct: 1603 KSPFLHSGMKMQKAGP-PVPASHIAPA-PVQP--PMIRRDITFPPGSVEATQPVLKQ 1655
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 43.1 bits (100), Expect = 0.001
Identities = 66/294 (22%), Positives = 110/294 (37%), Gaps = 46/294 (15%)
Query: 435 PSG-STSAHMPWDEFPSAGPKEA-PPWGKEQPL---HLEPSPPASPTQSPDNLTCTETPL 489
PSG P+ S P++ PP+ ++ P H +PS P P L ++ P
Sbjct: 459 PSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPY 518
Query: 490 VIAGN-------PA-YRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTT 541
+ PA Y S ++ Q P + P ++ +P+ P LS+
Sbjct: 519 SQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAA 578
Query: 542 VPQPEPETWEQI------------LRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQA 589
PQP+ + +Q L ++ A++AP + G QE ++ Q +
Sbjct: 579 YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSS 638
Query: 590 ----SAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDP 645
S + P G G A S +++S +S + G ++ + + P P PG
Sbjct: 639 LPDLSGSIDDLPMGTEG--ALSPGVSTSGISSSQ-GEQSNPAQSPFSPHTS--PHLPGIR 693
Query: 646 APVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQA 699
P P P+ SP S S P PG ++ P+PP Q +
Sbjct: 694 GPSPSPV----------GSPASVAQSRSGPLSPAAVPGNQMP--PRPPSGQSDS 735
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23
[Homo sapiens]
Length = 1636
Score = 43.1 bits (100), Expect = 0.001
Identities = 78/313 (24%), Positives = 104/313 (33%), Gaps = 60/313 (19%)
Query: 504 LSQSPCPRELGPDPLLARHLEEVEPEMPCVPQ---LSEPTTVPQPE-PETWEQILRRNVL 559
L + P PR P PLL R E E P+ P V P P+T+
Sbjct: 712 LKKKPPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFL-------- 763
Query: 560 QHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEK 619
+A P+ P S + G + G PPG Y + L+ A P
Sbjct: 764 ---GSATPLHFPPSPFP------SSTGPGPHYLSGPLPPGT--YSGPTQLIQPRAPGPH- 811
Query: 620 CGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLG 679
+P PG PA P P +T L P SPQ H SSP ++G
Sbjct: 812 -----------------AMPVAPG-PALYPAPAYTPELGLVPRSSPQ--HGVVSSP-YVG 850
Query: 680 LEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVM 739
+ P V +P P PQ + L + + T H TP
Sbjct: 851 VGPAPPVAGLPSAPPPQFSGPE-----LAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAP 905
Query: 740 ASPCCGCCCGDRSSPPTTPLRAPDPSPGGV--PLEASLCPASLAPSGI-SEKSKSSSSFH 796
PC PP PL P P G P+ A +S P+G + + H
Sbjct: 906 PPPCF-------PVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPH 958
Query: 797 PAPGNAQSSSQTP 809
P P +Q+ P
Sbjct: 959 PQPHPSQAFGPQP 971
Score = 36.2 bits (82), Expect = 0.13
Identities = 100/415 (24%), Positives = 132/415 (31%), Gaps = 90/415 (21%)
Query: 451 AGPKEAPPW-GKEQPLHLEPSP-PASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSP 508
AGP+ + G PLH PSP P+S P L+ P +G +Q
Sbjct: 754 AGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGP----------TQLI 803
Query: 509 CPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAPV 568
PR GP MP P P P P ++ R+ QHG ++P
Sbjct: 804 QPRAPGPHA------------MPVAPG---PALYPAPAYTPELGLVPRSSPQHGVVSSPY 848
Query: 569 -------------SAPTSGYQ--EFVHAVEQGGTQASAVVGLGPPGEAGYK--------- 604
SAP + E AV T ++ P A
Sbjct: 849 VGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPP 908
Query: 605 AFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIP--------GCPGDPAPVPVPLFTFG 656
F +P GA F IP G P P P P FG
Sbjct: 909 CFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFG 968
Query: 657 LDREPPRSP---QSSHL---------PSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLV 704
+PP+ P Q HL P SP +PG V P PPL + P
Sbjct: 969 --PQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPG--VLGQPPPPLHTQLYPGPAQ 1024
Query: 705 DSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPV------MASPCC--GCCCGDRS--SP 754
D L + AL G + H G P A+P G +S SP
Sbjct: 1025 DPLPAHS--GALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSP 1082
Query: 755 PTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSSSQTP 809
P AP P PG VP PA+ P + + ++ +P + +Q+P
Sbjct: 1083 HLVPSPAPSPGPGPVPPRP---PAAEPPPCLRRGAAAADLLSSSPESQHGGTQSP 1134
Score = 33.9 bits (76), Expect = 0.63
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 640 GCPGDPAPVPVPLFTFGLDREPPRS-PQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQ 698
G A +P P GL PP S P+S+ +PSSSP L E + +PP+P+
Sbjct: 1512 GLESPVASLPGPAEPPGL---PPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAP 1568
Query: 699 ATDPLVDSL 707
++ P SL
Sbjct: 1569 SSGPPSSSL 1577
Score = 30.0 bits (66), Expect = 9.1
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 457 PPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPD 516
PP G E P+ P P P P +L TP+ + P S+ L ++P P+E P
Sbjct: 1509 PPGGLESPVASLPGPAEPPGLPPASLP-ESTPIPSSSPP---PLSSPLPEAPQPKEEPPV 1564
Query: 517 P 517
P
Sbjct: 1565 P 1565
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 42.7 bits (99), Expect = 0.001
Identities = 89/392 (22%), Positives = 129/392 (32%), Gaps = 53/392 (13%)
Query: 434 PPSGSTSAHMPWDEFPSAGPKEAPPWGKEQP-LHLEPSPPASPTQSPDNLTCTE---TPL 489
P G+ + + P GP +PP G P PSP SP P T TP
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
Query: 490 VIAGNPAYRSFSNSLSQSPCP--RELGPDPLLARHLEEVEPEM--------PCVPQLSEP 539
G P + + S P + GP P A + P M P +P
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD 1401
Query: 540 TTVPQPEPETWEQILRRNVLQHGAAAA-------PVSAPTSGYQEFVHAVEQGGTQASAV 592
T P P + ++ V + GAA P P S + + +GG +
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461
Query: 593 VG------LGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPA 646
G + PP A + SS SP+K A+ G +IP P +
Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSS--SPKKAP--ATPAPMGAPTLPAVIPSSPKEVP 1517
Query: 647 PVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLG-----LEPGEKV---EDMPKPPLPQEQ 698
P R P +P ++ L +P L + P V + P P P+E
Sbjct: 1518 ATPS-------SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570
Query: 699 ATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTP 758
P S + T K ++ P + SP + P +P
Sbjct: 1571 PATPSSKEASSPPAVTPST------YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624
Query: 759 LRAP-DPSPGGVPLEASLCPASLAPSGISEKS 789
+ P P+P G P + P+SL S S S
Sbjct: 1625 EKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656
Score = 36.2 bits (82), Expect = 0.13
Identities = 84/394 (21%), Positives = 111/394 (28%), Gaps = 62/394 (15%)
Query: 434 PPSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAG 493
PP G+ + P G PP G P P +P TP
Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203
Query: 494 NPAYRSFSNSLSQSPC-PRELGPDPL--LARHLEEVEPEMPCVPQLSEPTTVPQPEPETW 550
+P + S +P P P P LA + P P S P P+
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK-- 1261
Query: 551 EQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLL 610
GA P + P S +G + V PP G A S
Sbjct: 1262 -----------GAPTPPAATPPSLKGGLATPPHKGAPNPAVVT---PPSPKGGPATSP-- 1305
Query: 611 ASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVP--------VPLFTFGLDREP- 661
A +P + G G P + G P PA P +P T P
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPK----GAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 662 -PRSPQSSHLPSSSPEHLG----LEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSAL 716
P S + P+++P H G P K P P P+ T P V L
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRG--PAIPSPKGDPTSPAVIPLSP------- 1412
Query: 717 TCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLC 776
+ TPV GD + P TP+ P
Sbjct: 1413 --------------KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458
Query: 777 PASLAPSGISEKSKSSSSFHPAPGNAQSSSQTPK 810
P+S + + S PAP +SS K
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492
Score = 32.0 bits (71), Expect = 2.4
Identities = 85/381 (22%), Positives = 110/381 (28%), Gaps = 31/381 (8%)
Query: 435 PSGSTSAHMPWDEFPSAGPKEAP-PWGKEQP-LHLEPSPPASPTQSPDNLTCTETPLVIA 492
P G+ + P P P P G P PSP SP +P TP
Sbjct: 1005 PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064
Query: 493 GNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQ 552
+P + SL +P P P + P P P P P+
Sbjct: 1065 PSPKGGPATPSLKGAPTP------PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG-- 1116
Query: 553 ILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGE-AGYKAFSSLLA 611
GA P + P S +G A P G A +
Sbjct: 1117 --LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
Query: 612 SSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLP 671
+A P G A+ +G P P P P P SP+ L
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG-LA 1233
Query: 672 SSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQE 731
+ SP+ G PP P+ P G+ +A L G L
Sbjct: 1234 TPSPK------GAPTTPAATPPSPKGGPATP--PPKGAPTPPAATPPSLKGGL--ATPPH 1283
Query: 732 DGGQTPVMASPCCGCCCGDRSSPP---TTPLRAPDPSPGGVPLEASLCPASLAPSGISEK 788
G P + +P G +SPP TP A PSP G P P AP+ +
Sbjct: 1284 KGAPNPAVVTP-PSPKGGPATSPPKGAPTPPAATPPSPKGSP---GTPPPKGAPTPPAVT 1339
Query: 789 SKSSSSFHPAPGNAQSSSQTP 809
S P SS P
Sbjct: 1340 PPSPKGTPTLPATTPSSKGGP 1360
Score = 31.2 bits (69), Expect = 4.1
Identities = 86/394 (21%), Positives = 118/394 (29%), Gaps = 54/394 (13%)
Query: 435 PSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPT------QSPDNLTCTETP 488
P+ P S+ PK+A + + PSP +PT SP T +P
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959
Query: 489 LVIAGNPAYRSFS-NSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEP 547
PA S +P P+ P + P P P V P P
Sbjct: 960 KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019
Query: 548 ETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFS 607
+ GA+ P + P S G+ A+ + G P
Sbjct: 1020 KGSP---AATPFPKGASTPPAATPPS----------PKGSPAATPLPKGAP--------- 1057
Query: 608 SLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQS 667
+A P G A+ +G P P P P G P +P S
Sbjct: 1058 --TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK---GAPMPPAATPPS 1112
Query: 668 SHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQC 727
++P H G PP P+ P G+ +A G L
Sbjct: 1113 PKGGLATPPH----KGAPTTPAATPPSPKGGLATP--PPKGAPTTPAATPPSPKGGL--A 1164
Query: 728 HGQEDGGQTPVMA---SPCCGCCCGDRSSPPTTPLRAPDPSPGGV----PLEASLCPASL 780
G T A SP G PTTP P GG+ P A PA+
Sbjct: 1165 TPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1224
Query: 781 APS---GISEKSKSSSSFHPA--PGNAQSSSQTP 809
PS G++ S + PA P + + TP
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATP 1258
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 42.0 bits (97), Expect = 0.002
Identities = 78/314 (24%), Positives = 116/314 (36%), Gaps = 65/314 (20%)
Query: 432 LLPPSGSTSAHMPWDEFPSAGPKEAP---PWGKEQPLHLEPSPPASPTQSPDNLTCTETP 488
LLP S+ PS+ P+ +P P E P+ PS P P+++P + TP
Sbjct: 1064 LLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPV---PSLPIRPSRAP-----SRTP 1115
Query: 489 LVIAGNPAYRSFS-NSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVP---- 543
G P+ +S ++ +P P++ PL EP+ P P+ P T P
Sbjct: 1116 ----GPPSAQSSPIDAQPATPLPQKDPAQPL--------EPKRPPPPRPVAPPTRPAPPQ 1163
Query: 544 QPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGT--------QASAVVGL 595
+P P + + + G AP S P +E G T Q S GL
Sbjct: 1164 RPPPPSGARSPAPTRKEFGGIGAPPS-PGVARREMEAPKSPGTTRKDNIGRSQPSPQAGL 1222
Query: 596 GPPGEAGYKAFSSLLASSA--VSPEKCGFGASSGE---EGYKPFQDLIPGCPGDPAPV-P 649
PG AGY + A +S + AS+G E + G P P+ P
Sbjct: 1223 AGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKP 1282
Query: 650 VPLFTFGLDREPPRS-------PQSSHLPSSSPEHLGLEPGEKVEDMPKPP--------L 694
F PP P ++ +P S P+ +E P+PP L
Sbjct: 1283 QAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQ-------PNLETPPQPPPRSRSSHSL 1335
Query: 695 PQEQATDPLVDSLG 708
P E ++ P V + G
Sbjct: 1336 PSEASSQPQVKTNG 1349
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 42.0 bits (97), Expect = 0.002
Identities = 62/229 (27%), Positives = 72/229 (31%), Gaps = 43/229 (18%)
Query: 579 VHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLI 638
V +E +A G GPP E G +V P AS EE P L
Sbjct: 1492 VRFLENCQPRAPVTSGRGPPSEDG-PGVPPPSPRRSVPPSPTSPRAS--EENGLPLLVLP 1548
Query: 639 PGCPGDPA---------PVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDM 689
P P P+P PL F E P SP + P P+ P
Sbjct: 1549 PPAPSVDVEDGEFLFVEPLPPPL-EFSNSFEKPESPLTPGPPHPLPD----TPAPATPLP 1603
Query: 690 PKPPLPQEQATDPLVDSLGSGIV-YSALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCC 748
P PP P A P +DS S + Y + L G P A+P
Sbjct: 1604 PVPP-PAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPA----- 1657
Query: 749 GDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHP 797
P P PDP PG SGI E SSS HP
Sbjct: 1658 ------PAAPQPGPDPPPG-------------TDSGIEEVDSRSSSDHP 1687
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 41.6 bits (96), Expect = 0.003
Identities = 78/351 (22%), Positives = 112/351 (31%), Gaps = 76/351 (21%)
Query: 434 PPSGSTSAHMPWDEFPSAGPKEAP--PWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVI 491
P G A P E GP + P P G +PL +P P Q P PL
Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGP 368
Query: 492 AGNPAYRSFSNS-LSQSPCPRELGPDPLLARH-LEEVEPEMPCVPQLSEPTTVPQPEPET 549
A PA ++ S S+ P P+ L P + + ++ P P Q+ P + Q
Sbjct: 369 AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ----- 423
Query: 550 WEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSL 609
+ + A P P V+Q G PG+
Sbjct: 424 -----QPGLQSPAKAPGPTKTP----------VQQPG-----------PGK--------- 448
Query: 610 LASSAVSPEKCGFGASSGEE-GYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSS 668
+ ++ G G +S ++ G +PG P P P + PP+ P S+
Sbjct: 449 -----IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA------KPPPQQPGSA 497
Query: 669 HLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCH 728
PS P +P + KP Q +T P GS K
Sbjct: 498 KPPSQQPG--STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA--------------KPSA 541
Query: 729 GQEDGGQTPVMAS--PCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCP 777
Q + S P G PPT A P G+P ++CP
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP--KTICP 590
Score = 40.8 bits (94), Expect = 0.005
Identities = 82/363 (22%), Positives = 120/363 (33%), Gaps = 48/363 (13%)
Query: 453 PKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRE 512
PK+ PP K+ LH PS A D+L+ P S + ++P +
Sbjct: 700 PKKPPPLVKQPTLHGSPSAKAKQPPEADSLS-------KPAPPKEPSVPSEQDKAPVADD 752
Query: 513 LGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNV--LQHGAAAAPVSA 570
P + V+P V S T P + Q + L+ +A S
Sbjct: 753 KPKQPKM------VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSF 806
Query: 571 PTSGYQEF---VHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSG 627
P +G + A+ + + + + GP E+ V P +
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES--------KGQKQVDPVQKKEEPKKA 858
Query: 628 EEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVE 687
+ P D P G P P P P T G + +PQ S P L G +
Sbjct: 859 QTKMSPKPDAKPMPKGSPTP-PGPRPTAG---QTVPTPQQSPKPQEQSRRFSLNLG-SIT 913
Query: 688 DMPK--PPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCG 745
D PK P PQE T L G+ I A H Q G P+ +P
Sbjct: 914 DAPKSQPTTPQETVTGKLF-GFGASIFSQASNLISTAGQPGPHSQSGPG-APMKQAPA-- 969
Query: 746 CCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSS 805
S PPT+ + P S G +A PA P K+ ++ P A +
Sbjct: 970 -----PSQPPTS--QGPPKSTG----QAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
Query: 806 SQT 808
+T
Sbjct: 1019 KRT 1021
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 41.6 bits (96), Expect = 0.003
Identities = 78/351 (22%), Positives = 112/351 (31%), Gaps = 76/351 (21%)
Query: 434 PPSGSTSAHMPWDEFPSAGPKEAP--PWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVI 491
P G A P E GP + P P G +PL +P P Q P PL
Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGP 368
Query: 492 AGNPAYRSFSNS-LSQSPCPRELGPDPLLARH-LEEVEPEMPCVPQLSEPTTVPQPEPET 549
A PA ++ S S+ P P+ L P + + ++ P P Q+ P + Q
Sbjct: 369 AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ----- 423
Query: 550 WEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSL 609
+ + A P P V+Q G PG+
Sbjct: 424 -----QPGLQSPAKAPGPTKTP----------VQQPG-----------PGK--------- 448
Query: 610 LASSAVSPEKCGFGASSGEE-GYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSS 668
+ ++ G G +S ++ G +PG P P P + PP+ P S+
Sbjct: 449 -----IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA------KPPPQQPGSA 497
Query: 669 HLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCH 728
PS P +P + KP Q +T P GS K
Sbjct: 498 KPPSQQPG--STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA--------------KPSA 541
Query: 729 GQEDGGQTPVMAS--PCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCP 777
Q + S P G PPT A P G+P ++CP
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP--KTICP 590
Score = 40.8 bits (94), Expect = 0.005
Identities = 82/363 (22%), Positives = 120/363 (33%), Gaps = 48/363 (13%)
Query: 453 PKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRE 512
PK+ PP K+ LH PS A D+L+ P S + ++P +
Sbjct: 700 PKKPPPLVKQPTLHGSPSAKAKQPPEADSLS-------KPAPPKEPSVPSEQDKAPVADD 752
Query: 513 LGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNV--LQHGAAAAPVSA 570
P + V+P V S T P + Q + L+ +A S
Sbjct: 753 KPKQPKM------VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSF 806
Query: 571 PTSGYQEF---VHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSG 627
P +G + A+ + + + + GP E+ V P +
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES--------KGQKQVDPVQKKEEPKKA 858
Query: 628 EEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVE 687
+ P D P G P P P P T G + +PQ S P L G +
Sbjct: 859 QTKMSPKPDAKPMPKGSPTP-PGPRPTAG---QTVPTPQQSPKPQEQSRRFSLNLG-SIT 913
Query: 688 DMPK--PPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCG 745
D PK P PQE T L G+ I A H Q G P+ +P
Sbjct: 914 DAPKSQPTTPQETVTGKLF-GFGASIFSQASNLISTAGQPGPHSQSGPG-APMKQAPA-- 969
Query: 746 CCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSS 805
S PPT+ + P S G +A PA P K+ ++ P A +
Sbjct: 970 -----PSQPPTS--QGPPKSTG----QAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
Query: 806 SQT 808
+T
Sbjct: 1019 KRT 1021
>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 1 [Homo sapiens]
Length = 1075
Score = 40.8 bits (94), Expect = 0.005
Identities = 79/318 (24%), Positives = 111/318 (34%), Gaps = 40/318 (12%)
Query: 469 PSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPD-PLLARHLEEVE 527
P P + TQ P + + V++G RS S+ Q+ P L E V
Sbjct: 719 PVPHPAQTQRPSSDSGCSHDSVLSGQ---RSLICSIPQTYASMVTSSHLPQLQCRDESVS 775
Query: 528 PEMPCVPQ--LSEPTTV-PQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQ 584
E +P + +P V P P + Q ++ NV+ +G P++A +S QEF + Q
Sbjct: 776 KEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASS--QEFDSVLFQ 833
Query: 585 GGTQASAVVGLG-------PPGEAGYKAFSSLLASSAVS----PEKCGFGASSGEEGYK- 632
S +V LG P + + LLA + S P G G +
Sbjct: 834 QDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRS 893
Query: 633 ---PFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDM 689
P D I G P P+ SP +SH +SSP +
Sbjct: 894 LSSPVADQITGQPSSQLQ-PITYGPSHSGSATTASPAASHPLASSP-------------L 939
Query: 690 PKPPLPQEQATDPLVDSLGSGIVYSALT-CHLCGHLKQCHGQEDGGQTPVMASPCCGCCC 748
PP PQ Q S G+ S T H H Q GG + +S C C
Sbjct: 940 SGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLS-APSSLICHSLC 998
Query: 749 GDRSSPPTTPLRAPDPSP 766
S PP + P P
Sbjct: 999 DPASFPPDGATVSIKPEP 1016
>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 4 [Homo sapiens]
Length = 1045
Score = 40.8 bits (94), Expect = 0.005
Identities = 79/318 (24%), Positives = 111/318 (34%), Gaps = 40/318 (12%)
Query: 469 PSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPD-PLLARHLEEVE 527
P P + TQ P + + V++G RS S+ Q+ P L E V
Sbjct: 719 PVPHPAQTQRPSSDSGCSHDSVLSGQ---RSLICSIPQTYASMVTSSHLPQLQCRDESVS 775
Query: 528 PEMPCVPQ--LSEPTTV-PQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQ 584
E +P + +P V P P + Q ++ NV+ +G P++A +S QEF + Q
Sbjct: 776 KEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASS--QEFDSVLFQ 833
Query: 585 GGTQASAVVGLG-------PPGEAGYKAFSSLLASSAVS----PEKCGFGASSGEEGYK- 632
S +V LG P + + LLA + S P G G +
Sbjct: 834 QDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRS 893
Query: 633 ---PFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDM 689
P D I G P P+ SP +SH +SSP +
Sbjct: 894 LSSPVADQITGQPSSQLQ-PITYGPSHSGSATTASPAASHPLASSP-------------L 939
Query: 690 PKPPLPQEQATDPLVDSLGSGIVYSALT-CHLCGHLKQCHGQEDGGQTPVMASPCCGCCC 748
PP PQ Q S G+ S T H H Q GG + +S C C
Sbjct: 940 SGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLS-APSSLICHSLC 998
Query: 749 GDRSSPPTTPLRAPDPSP 766
S PP + P P
Sbjct: 999 DPASFPPDGATVSIKPEP 1016
>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 3 [Homo sapiens]
Length = 1065
Score = 40.8 bits (94), Expect = 0.005
Identities = 79/318 (24%), Positives = 111/318 (34%), Gaps = 40/318 (12%)
Query: 469 PSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPD-PLLARHLEEVE 527
P P + TQ P + + V++G RS S+ Q+ P L E V
Sbjct: 719 PVPHPAQTQRPSSDSGCSHDSVLSGQ---RSLICSIPQTYASMVTSSHLPQLQCRDESVS 775
Query: 528 PEMPCVPQ--LSEPTTV-PQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQ 584
E +P + +P V P P + Q ++ NV+ +G P++A +S QEF + Q
Sbjct: 776 KEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASS--QEFDSVLFQ 833
Query: 585 GGTQASAVVGLG-------PPGEAGYKAFSSLLASSAVS----PEKCGFGASSGEEGYK- 632
S +V LG P + + LLA + S P G G +
Sbjct: 834 QDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRS 893
Query: 633 ---PFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDM 689
P D I G P P+ SP +SH +SSP +
Sbjct: 894 LSSPVADQITGQPSSQLQ-PITYGPSHSGSATTASPAASHPLASSP-------------L 939
Query: 690 PKPPLPQEQATDPLVDSLGSGIVYSALT-CHLCGHLKQCHGQEDGGQTPVMASPCCGCCC 748
PP PQ Q S G+ S T H H Q GG + +S C C
Sbjct: 940 SGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLS-APSSLICHSLC 998
Query: 749 GDRSSPPTTPLRAPDPSP 766
S PP + P P
Sbjct: 999 DPASFPPDGATVSIKPEP 1016
>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 2 [Homo sapiens]
Length = 1068
Score = 40.8 bits (94), Expect = 0.005
Identities = 79/318 (24%), Positives = 111/318 (34%), Gaps = 40/318 (12%)
Query: 469 PSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPD-PLLARHLEEVE 527
P P + TQ P + + V++G RS S+ Q+ P L E V
Sbjct: 719 PVPHPAQTQRPSSDSGCSHDSVLSGQ---RSLICSIPQTYASMVTSSHLPQLQCRDESVS 775
Query: 528 PEMPCVPQ--LSEPTTV-PQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQ 584
E +P + +P V P P + Q ++ NV+ +G P++A +S QEF + Q
Sbjct: 776 KEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASS--QEFDSVLFQ 833
Query: 585 GGTQASAVVGLG-------PPGEAGYKAFSSLLASSAVS----PEKCGFGASSGEEGYK- 632
S +V LG P + + LLA + S P G G +
Sbjct: 834 QDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRS 893
Query: 633 ---PFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDM 689
P D I G P P+ SP +SH +SSP +
Sbjct: 894 LSSPVADQITGQPSSQLQ-PITYGPSHSGSATTASPAASHPLASSP-------------L 939
Query: 690 PKPPLPQEQATDPLVDSLGSGIVYSALT-CHLCGHLKQCHGQEDGGQTPVMASPCCGCCC 748
PP PQ Q S G+ S T H H Q GG + +S C C
Sbjct: 940 SGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLS-APSSLICHSLC 998
Query: 749 GDRSSPPTTPLRAPDPSP 766
S PP + P P
Sbjct: 999 DPASFPPDGATVSIKPEP 1016
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,763,108
Number of Sequences: 37866
Number of extensions: 2598162
Number of successful extensions: 12478
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 455
Number of HSP's that attempted gapping in prelim test: 10978
Number of HSP's gapped (non-prelim): 1845
length of query: 825
length of database: 18,247,518
effective HSP length: 111
effective length of query: 714
effective length of database: 14,044,392
effective search space: 10027695888
effective search space used: 10027695888
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.