Guide to the Human Genome
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Search of human proteins with 45333909

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45333909 COMM domain containing 6 isoform a [Homo sapiens]
         (98 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45333909 COMM domain containing 6 isoform a [Homo sapiens]         195   6e-51
gi|45333906 COMM domain containing 6 isoform b [Homo sapiens]         164   1e-41
gi|8923458 COMM domain containing 8 [Homo sapiens]                     38   0.002
gi|151101369 COMM domain containing 7 isoform 1 [Homo sapiens]         33   0.049
gi|151101367 COMM domain containing 7 isoform 2 [Homo sapiens]         33   0.049
gi|124487382 COMM domain containing 5 [Homo sapiens]                   28   1.2  
gi|154800418 COMM domain containing 5 [Homo sapiens]                   28   1.2  
gi|19923430 COMM domain containing 5 [Homo sapiens]                    28   1.2  
gi|169166962 PREDICTED: similar to COMM domain containing 5 [Hom...    27   3.5  
gi|169166771 PREDICTED: similar to COMM domain containing 5 [Hom...    27   3.5  
gi|169166418 PREDICTED: similar to COMM domain containing 5 [Hom...    27   3.5  
gi|4758416 golgi-specific brefeldin A resistant guanine nucleoti...    27   3.5  
gi|9994185 RNA binding motif protein 7 [Homo sapiens]                  27   4.6  
gi|170784846 kelch-like 7 isoform 1 [Homo sapiens]                     26   6.0  
gi|170784844 kelch-like 7 isoform 2 [Homo sapiens]                     26   6.0  
gi|156416007 COMM domain containing 9 isoform 2 [Homo sapiens]         26   7.8  
gi|156416005 COMM domain containing 9 isoform 1 [Homo sapiens]         26   7.8  

>gi|45333909 COMM domain containing 6 isoform a [Homo sapiens]
          Length = 98

 Score =  195 bits (496), Expect = 6e-51
 Identities = 98/98 (100%), Positives = 98/98 (100%)

Query: 1  MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC 60
          MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC
Sbjct: 1  MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC 60

Query: 61 FEMTIPQFQPQLLATSSLLSASNFYRQFKEIAAVIETV 98
          FEMTIPQFQPQLLATSSLLSASNFYRQFKEIAAVIETV
Sbjct: 61 FEMTIPQFQPQLLATSSLLSASNFYRQFKEIAAVIETV 98


>gi|45333906 COMM domain containing 6 isoform b [Homo sapiens]
          Length = 85

 Score =  164 bits (415), Expect = 1e-41
 Identities = 85/98 (86%), Positives = 85/98 (86%), Gaps = 13/98 (13%)

Query: 1  MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC 60
          MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC
Sbjct: 1  MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC 60

Query: 61 FEMTIPQFQPQLLATSSLLSASNFYRQFKEIAAVIETV 98
          FEMTIPQFQ             NFYRQFKEIAAVIETV
Sbjct: 61 FEMTIPQFQ-------------NFYRQFKEIAAVIETV 85


>gi|8923458 COMM domain containing 8 [Homo sapiens]
          Length = 183

 Score = 37.7 bits (86), Expect = 0.002
 Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 4/72 (5%)

Query: 18  QLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQPQLLATSS 77
           QL DF W++ +A+SSD   +L+ P +++ L V + +G+VK    EM+  + Q  +    S
Sbjct: 116 QLQDFDWQVKLALSSDKIAALRMPLLSLHLDVKE-NGEVKPYSIEMSREELQNLI---QS 171

Query: 78  LLSASNFYRQFK 89
           L +A+    Q K
Sbjct: 172 LEAANKVVLQLK 183


>gi|151101369 COMM domain containing 7 isoform 1 [Homo sapiens]
          Length = 200

 Score = 33.1 bits (74), Expect = 0.049
 Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 17  NQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQF 68
           NQL+D +WK G+   S     +   ++ + L V     Q +    E+T+PQF
Sbjct: 132 NQLIDMEWKFGVTSGSSELEKVGSIFLQLKL-VVKKGNQTENVYIELTLPQF 182


>gi|151101367 COMM domain containing 7 isoform 2 [Homo sapiens]
          Length = 199

 Score = 33.1 bits (74), Expect = 0.049
 Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 17  NQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQF 68
           NQL+D +WK G+   S     +   ++ + L V     Q +    E+T+PQF
Sbjct: 131 NQLIDMEWKFGVTSGSSELEKVGSIFLQLKL-VVKKGNQTENVYIELTLPQF 181


>gi|124487382 COMM domain containing 5 [Homo sapiens]
          Length = 224

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DF+W++ +A+S+        P V + LK++D S       FE+   +FQ
Sbjct: 152 VADFRWRVDVAISTSALARSLQPSVLMQLKLSDGSAY----RFEVPTAKFQ 198


>gi|154800418 COMM domain containing 5 [Homo sapiens]
          Length = 224

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DF+W++ +A+S+        P V + LK++D S       FE+   +FQ
Sbjct: 152 VADFRWRVDVAISTSALARSLQPSVLMQLKLSDGSAY----RFEVPTAKFQ 198


>gi|19923430 COMM domain containing 5 [Homo sapiens]
          Length = 224

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DF+W++ +A+S+        P V + LK++D S       FE+   +FQ
Sbjct: 152 VADFRWRVDVAISTSALARSLQPSVLMQLKLSDGSAY----RFEVPTAKFQ 198


>gi|169166962 PREDICTED: similar to COMM domain containing 5 [Homo
           sapiens]
          Length = 273

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DFQW + + +S+        P V + LK++D         FE+ I +FQ
Sbjct: 201 VADFQWWVDVTISTSALARFLQPRVLMQLKLSDGLAY----RFEVPIAKFQ 247


>gi|169166771 PREDICTED: similar to COMM domain containing 5 [Homo
           sapiens]
          Length = 273

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DFQW + + +S+        P V + LK++D         FE+ I +FQ
Sbjct: 201 VADFQWWVDVTISTSALARFLQPRVLMQLKLSDGLAY----RFEVPIAKFQ 247


>gi|169166418 PREDICTED: similar to COMM domain containing 5 [Homo
           sapiens]
          Length = 273

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DFQW + + +S+        P V + LK++D         FE+ I +FQ
Sbjct: 201 VADFQWWVDVTISTSALARFLQPRVLMQLKLSDGLAY----RFEVPIAKFQ 247


>gi|4758416 golgi-specific brefeldin A resistant guanine nucleotide
           exchange factor 1 [Homo sapiens]
          Length = 1859

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 2/42 (4%)

Query: 31  SSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQPQL 72
           +SD C SL Y    +ML    H+  V+ +   MT+ +F+  L
Sbjct: 819 NSDACFSLAY--AVIMLNTDQHNHNVRKQNAPMTLEEFRKNL 858


>gi|9994185 RNA binding motif protein 7 [Homo sapiens]
          Length = 266

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 13/43 (30%), Positives = 19/43 (44%)

Query: 2   EASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVA 44
           ++   P + + S   NQ    QW+ G   S    R   YPY+A
Sbjct: 167 QSGFSPSVQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLA 209


>gi|170784846 kelch-like 7 isoform 1 [Homo sapiens]
          Length = 586

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 11/29 (37%), Positives = 20/29 (68%)

Query: 10  DAKSDVTNQLVDFQWKLGMAVSSDTCRSL 38
           DA+ D+  QLV+F +   ++V+S+  +SL
Sbjct: 89  DAEPDIIEQLVEFAYTARISVNSNNVQSL 117


>gi|170784844 kelch-like 7 isoform 2 [Homo sapiens]
          Length = 564

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 11/29 (37%), Positives = 20/29 (68%)

Query: 10 DAKSDVTNQLVDFQWKLGMAVSSDTCRSL 38
          DA+ D+  QLV+F +   ++V+S+  +SL
Sbjct: 67 DAEPDIIEQLVEFAYTARISVNSNNVQSL 95


>gi|156416007 COMM domain containing 9 isoform 2 [Homo sapiens]
          Length = 156

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 9/34 (26%), Positives = 19/34 (55%)

Query: 18  QLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVAD 51
           +LVD  W++ +  SSD+   +  P   + +K+ +
Sbjct: 80  RLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQE 113


>gi|156416005 COMM domain containing 9 isoform 1 [Homo sapiens]
          Length = 198

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 9/34 (26%), Positives = 19/34 (55%)

Query: 18  QLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVAD 51
           +LVD  W++ +  SSD+   +  P   + +K+ +
Sbjct: 122 RLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQE 155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.127    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,995,306
Number of Sequences: 37866
Number of extensions: 90329
Number of successful extensions: 178
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 163
Number of HSP's gapped (non-prelim): 17
length of query: 98
length of database: 18,247,518
effective HSP length: 69
effective length of query: 29
effective length of database: 15,634,764
effective search space: 453408156
effective search space used: 453408156
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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