Search of human proteins with 4507791

Search of human proteins with 4507791

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507791 ubiquitin-conjugating enzyme E2M [Homo sapiens]
         (183 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507791 ubiquitin-conjugating enzyme E2M [Homo sapiens]            378   e-105
gi|18087857 NEDD8-conjugating enzyme [Homo sapiens]                   117   6e-27
gi|4507775 ubiquitin-conjugating enzyme E2D 2 isoform 1 [Homo sa...    94   5e-20
gi|4507773 ubiquitin-conjugating enzyme E2D 1 [Homo sapiens]           94   9e-20
gi|8393719 ubiquitin-conjugating enzyme E2D 4 (putative) [Homo s...    93   1e-19
gi|33149322 ubiquitin-conjugating enzyme E2D 3 isoform 2 [Homo s...    92   3e-19
gi|33149320 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    92   3e-19
gi|33149318 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    92   3e-19
gi|33149316 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    92   3e-19
gi|33149314 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    92   3e-19
gi|33149312 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    92   3e-19
gi|33149310 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s...    92   3e-19
gi|4507777 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo sa...    92   3e-19
gi|33149324 ubiquitin-conjugating enzyme E2D 3 isoform 3 [Homo s...    90   1e-18
gi|32967280 ubiquitin-conjugating enzyme E2A isoform 1 [Homo sap...    89   2e-18
gi|4507771 ubiquitin-conjugating enzyme E2B [Homo sapiens]             89   2e-18
gi|33188456 ubiquitin-conjugating enzyme E2D 2 isoform 2 [Homo s...    88   4e-18
gi|5902146 ubiquitin-conjugating enzyme E2C isoform 1 [Homo sapi...    87   8e-18
gi|22749327 ubiquitin-conjugating enzyme E2E 2 [Homo sapiens]          87   1e-17
gi|33359694 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]          86   1e-17
gi|5454146 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]           86   1e-17
gi|4507779 ubiquitin-conjugating enzyme E2E 1 isoform 1 [Homo sa...    85   3e-17
gi|4507789 ubiquitin-conjugating enzyme E2L 3 isoform 1 [Homo sa...    84   5e-17
gi|32967289 ubiquitin-conjugating enzyme E2C isoform 4 [Homo sap...    82   3e-16
gi|32967287 ubiquitin-conjugating enzyme E2C isoform 4 [Homo sap...    82   3e-16
gi|4507793 ubiquitin-conjugating enzyme E2N [Homo sapiens]             82   3e-16
gi|32967285 ubiquitin-conjugating enzyme E2C isoform 3 [Homo sap...    81   4e-16
gi|35494003 ubiquitin-conjugating enzyme E2I [Homo sapiens]            80   7e-16
gi|35493996 ubiquitin-conjugating enzyme E2I [Homo sapiens]            80   7e-16
gi|35493987 ubiquitin-conjugating enzyme E2I [Homo sapiens]            80   7e-16

>gi|4507791 ubiquitin-conjugating enzyme E2M [Homo sapiens]
          Length = 183

 Score =  378 bits (970), Expect = e-105
 Identities = 183/183 (100%), Positives = 183/183 (100%)

Query: 1   MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNF 60
           MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNF
Sbjct: 1   MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNF 60

Query: 61  KLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWK 120
           KLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWK
Sbjct: 61  KLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWK 120

Query: 121 PVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFER 180
           PVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFER
Sbjct: 121 PVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFER 180

Query: 181 CLK 183
           CLK
Sbjct: 181 CLK 183


>gi|18087857 NEDD8-conjugating enzyme [Homo sapiens]
          Length = 185

 Score =  117 bits (293), Expect = 6e-27
 Identities = 64/162 (39%), Positives = 91/162 (56%), Gaps = 9/162 (5%)

Query: 12  KEEESAGGTKGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDPDDLLNFKLVICPDEG 69
           K   +A     S+++ S     + K++ EL  NLP TC + F DP+ L  F+L + PDEG
Sbjct: 15  KGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEG 74

Query: 70  FYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE------DWKPVL 123
           +Y+ GKF F  +V   Y   PPKVKC T ++HPNI   G +CL++LRE       W P  
Sbjct: 75  YYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTR 134

Query: 124 TINSIIYGLQYLFLE-PNPEDPLNKEAAEVLQNNRRLFEQNV 164
           T+  +++GL  LF +  N +DPLN EAAE    ++  F   V
Sbjct: 135 TLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKV 176


>gi|4507775 ubiquitin-conjugating enzyme E2D 2 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 94.4 bits (233), Expect = 5e-20
 Identities = 47/133 (35%), Positives = 75/133 (56%), Gaps = 4/133 (3%)

Query: 33  RIQKDINEL--NLPKTCDISFSDPDDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHD 89
           RI K++N+L  + P  C       DD+ +++  I  P++  Y+ G F  +      YP  
Sbjct: 5   RIHKELNDLARDPPAQCSAG-PVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63

Query: 90  PPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEA 149
           PPKV   T +YHPNI+  G++CL+ILR  W P LTI+ ++  +  L  +PNP+DPL  E 
Sbjct: 64  PPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEI 123

Query: 150 AEVLQNNRRLFEQ 162
           A + + +R  + +
Sbjct: 124 ARIYKTDREKYNR 136


>gi|4507773 ubiquitin-conjugating enzyme E2D 1 [Homo sapiens]
          Length = 147

 Score = 93.6 bits (231), Expect = 9e-20
 Identities = 43/135 (31%), Positives = 77/135 (57%), Gaps = 2/135 (1%)

Query: 33  RIQKDINELNLPKTCDISFSDP-DDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHDP 90
           RIQK++++L        S     DDL +++  I  P +  Y+ G F  +      YP  P
Sbjct: 5   RIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKP 64

Query: 91  PKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAA 150
           PK+   T +YHPNI+  G++CL+ILR  W P LT++ ++  +  L  +PNP+DPL  + A
Sbjct: 65  PKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIA 124

Query: 151 EVLQNNRRLFEQNVQ 165
           ++ ++++  + ++ +
Sbjct: 125 QIYKSDKEKYNRHAR 139


>gi|8393719 ubiquitin-conjugating enzyme E2D 4 (putative) [Homo
           sapiens]
          Length = 147

 Score = 92.8 bits (229), Expect = 1e-19
 Identities = 46/132 (34%), Positives = 72/132 (54%), Gaps = 2/132 (1%)

Query: 33  RIQKDINELNLPKTCDISFSDP-DDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHDP 90
           RIQK++ +L        S     DDL +++  I  P++  Y+ G F  +      YP  P
Sbjct: 5   RIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKP 64

Query: 91  PKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAA 150
           PKV   T +YHPNI+  G++CL+ILR  W P LT++ ++  +  L  +PNP+DPL  E A
Sbjct: 65  PKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPEIA 124

Query: 151 EVLQNNRRLFEQ 162
              + +R  + +
Sbjct: 125 HTYKADREKYNR 136


>gi|33149322 ubiquitin-conjugating enzyme E2D 3 isoform 2 [Homo
           sapiens]
          Length = 148

 Score = 91.7 bits (226), Expect = 3e-19
 Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 4/128 (3%)

Query: 33  RIQKDINEL--NLPKTCDISFSDPDDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHD 89
           RI K++++L  + P  C       DD+ +++  I  P++  Y+ G F  +      YP  
Sbjct: 5   RINKELSDLARDPPAQCSAG-PVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63

Query: 90  PPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEA 149
           PPKV   T +YHPNI+  G++CL+ILR  W P LTI+ ++  +  L  +PNP+DPL  E 
Sbjct: 64  PPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEI 123

Query: 150 AEVLQNNR 157
           A + + +R
Sbjct: 124 ARIYKTDR 131


>gi|33149320 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 91.7 bits (226), Expect = 3e-19
 Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 4/128 (3%)

Query: 33  RIQKDINEL--NLPKTCDISFSDPDDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHD 89
           RI K++++L  + P  C       DD+ +++  I  P++  Y+ G F  +      YP  
Sbjct: 5   RINKELSDLARDPPAQCSAG-PVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63

Query: 90  PPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEA 149
           PPKV   T +YHPNI+  G++CL+ILR  W P LTI+ ++  +  L  +PNP+DPL  E 
Sbjct: 64  PPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEI 123

Query: 150 AEVLQNNR 157
           A + + +R
Sbjct: 124 ARIYKTDR 131


>gi|33149318 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 91.7 bits (226), Expect = 3e-19
 Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 4/128 (3%)

Query: 33  RIQKDINEL--NLPKTCDISFSDPDDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHD 89
           RI K++++L  + P  C       DD+ +++  I  P++  Y+ G F  +      YP  
Sbjct: 5   RINKELSDLARDPPAQCSAG-PVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63

Query: 90  PPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEA 149
           PPKV   T +YHPNI+  G++CL+ILR  W P LTI+ ++  +  L  +PNP+DPL  E 
Sbjct: 64  PPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEI 123

Query: 150 AEVLQNNR 157
           A + + +R
Sbjct: 124 ARIYKTDR 131


>gi|33149316 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 91.7 bits (226), Expect = 3e-19
 Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 4/128 (3%)

Query: 33  RIQKDINEL--NLPKTCDISFSDPDDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHD 89
           RI K++++L  + P  C       DD+ +++  I  P++  Y+ G F  +      YP  
Sbjct: 5   RINKELSDLARDPPAQCSAG-PVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63

Query: 90  PPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEA 149
           PPKV   T +YHPNI+  G++CL+ILR  W P LTI+ ++  +  L  +PNP+DPL  E 
Sbjct: 64  PPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEI 123

Query: 150 AEVLQNNR 157
           A + + +R
Sbjct: 124 ARIYKTDR 131


>gi|33149314 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 91.7 bits (226), Expect = 3e-19
 Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 4/128 (3%)

Query: 33  RIQKDINEL--NLPKTCDISFSDPDDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHD 89
           RI K++++L  + P  C       DD+ +++  I  P++  Y+ G F  +      YP  
Sbjct: 5   RINKELSDLARDPPAQCSAG-PVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63

Query: 90  PPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEA 149
           PPKV   T +YHPNI+  G++CL+ILR  W P LTI+ ++  +  L  +PNP+DPL  E 
Sbjct: 64  PPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEI 123

Query: 150 AEVLQNNR 157
           A + + +R
Sbjct: 124 ARIYKTDR 131


>gi|33149312 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 91.7 bits (226), Expect = 3e-19
 Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 4/128 (3%)

Query: 33  RIQKDINEL--NLPKTCDISFSDPDDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHD 89
           RI K++++L  + P  C       DD+ +++  I  P++  Y+ G F  +      YP  
Sbjct: 5   RINKELSDLARDPPAQCSAG-PVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63

Query: 90  PPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEA 149
           PPKV   T +YHPNI+  G++CL+ILR  W P LTI+ ++  +  L  +PNP+DPL  E 
Sbjct: 64  PPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEI 123

Query: 150 AEVLQNNR 157
           A + + +R
Sbjct: 124 ARIYKTDR 131


>gi|33149310 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 91.7 bits (226), Expect = 3e-19
 Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 4/128 (3%)

Query: 33  RIQKDINEL--NLPKTCDISFSDPDDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHD 89
           RI K++++L  + P  C       DD+ +++  I  P++  Y+ G F  +      YP  
Sbjct: 5   RINKELSDLARDPPAQCSAG-PVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63

Query: 90  PPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEA 149
           PPKV   T +YHPNI+  G++CL+ILR  W P LTI+ ++  +  L  +PNP+DPL  E 
Sbjct: 64  PPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEI 123

Query: 150 AEVLQNNR 157
           A + + +R
Sbjct: 124 ARIYKTDR 131


>gi|4507777 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
           sapiens]
          Length = 147

 Score = 91.7 bits (226), Expect = 3e-19
 Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 4/128 (3%)

Query: 33  RIQKDINEL--NLPKTCDISFSDPDDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHD 89
           RI K++++L  + P  C       DD+ +++  I  P++  Y+ G F  +      YP  
Sbjct: 5   RINKELSDLARDPPAQCSAG-PVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63

Query: 90  PPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEA 149
           PPKV   T +YHPNI+  G++CL+ILR  W P LTI+ ++  +  L  +PNP+DPL  E 
Sbjct: 64  PPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEI 123

Query: 150 AEVLQNNR 157
           A + + +R
Sbjct: 124 ARIYKTDR 131


>gi|33149324 ubiquitin-conjugating enzyme E2D 3 isoform 3 [Homo
           sapiens]
          Length = 149

 Score = 89.7 bits (221), Expect = 1e-18
 Identities = 40/104 (38%), Positives = 62/104 (59%), Gaps = 1/104 (0%)

Query: 55  DDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLN 113
           DD+ +++  I  P++  Y+ G F  +      YP  PPKV   T +YHPNI+  G++CL+
Sbjct: 30  DDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLD 89

Query: 114 ILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNR 157
           ILR  W P LTI+ ++  +  L  +PNP+DPL  E A + + +R
Sbjct: 90  ILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDR 133


>gi|32967280 ubiquitin-conjugating enzyme E2A isoform 1 [Homo
           sapiens]
          Length = 152

 Score = 89.0 bits (219), Expect = 2e-18
 Identities = 43/140 (30%), Positives = 81/140 (57%), Gaps = 2/140 (1%)

Query: 27  ASAAQLRIQKDINELNLPKTCDISFSDPDD-LLNFKLVICPDEGF-YKSGKFVFSFKVGQ 84
           ++ A+ R+ +D   L       +S +  ++ ++ +  VI   EG  ++ G F  + +  +
Sbjct: 2   STPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTE 61

Query: 85  GYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDP 144
            YP+ PP V+  + ++HPN+  +G++CL+IL+  W P   ++SI+  +Q L  EPNP  P
Sbjct: 62  EYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSP 121

Query: 145 LNKEAAEVLQNNRRLFEQNV 164
            N +AA++ Q N+R +E+ V
Sbjct: 122 ANSQAAQLYQENKREYEKRV 141


>gi|4507771 ubiquitin-conjugating enzyme E2B [Homo sapiens]
          Length = 152

 Score = 89.0 bits (219), Expect = 2e-18
 Identities = 43/140 (30%), Positives = 80/140 (57%), Gaps = 2/140 (1%)

Query: 27  ASAAQLRIQKDINELNLPKTCDISFSDPDD-LLNFKLVICPDEGF-YKSGKFVFSFKVGQ 84
           ++ A+ R+ +D   L       +S +  ++ ++ +  VI   EG  ++ G F    +  +
Sbjct: 2   STPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSE 61

Query: 85  GYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDP 144
            YP+ PP V+  + ++HPN+  +G++CL+IL+  W P   ++SI+  +Q L  EPNP  P
Sbjct: 62  EYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSP 121

Query: 145 LNKEAAEVLQNNRRLFEQNV 164
            N +AA++ Q N+R +E+ V
Sbjct: 122 ANSQAAQLYQENKREYEKRV 141


>gi|33188456 ubiquitin-conjugating enzyme E2D 2 isoform 2 [Homo
           sapiens]
          Length = 118

 Score = 88.2 bits (217), Expect = 4e-18
 Identities = 37/100 (37%), Positives = 59/100 (59%)

Query: 63  VICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPV 122
           ++ P++  Y+ G F  +      YP  PPKV   T +YHPNI+  G++CL+ILR  W P 
Sbjct: 8   IMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPA 67

Query: 123 LTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQ 162
           LTI+ ++  +  L  +PNP+DPL  E A + + +R  + +
Sbjct: 68  LTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNR 107


>gi|5902146 ubiquitin-conjugating enzyme E2C isoform 1 [Homo
           sapiens]
          Length = 179

 Score = 87.0 bits (214), Expect = 8e-18
 Identities = 51/148 (34%), Positives = 80/148 (54%), Gaps = 8/148 (5%)

Query: 10  QKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDIS-FSDPDDLLNFKLVICPDE 68
           +K  E S G  +G   K      R+Q+++  L +     IS F + D+L  +   I    
Sbjct: 17  RKGAEPSGGAARGPVGK------RLQQELMTLMMSGDKGISAFPESDNLFKWVGTIHGAA 70

Query: 69  G-FYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINS 127
           G  Y+  ++  S +   GYP++ P VK  T  YHPN+D +GN+CL+IL+E W  +  + +
Sbjct: 71  GTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKEKWSALYDVRT 130

Query: 128 IIYGLQYLFLEPNPEDPLNKEAAEVLQN 155
           I+  +Q L  EPN + PLN  AAE+ +N
Sbjct: 131 ILLSIQSLLGEPNIDSPLNTHAAELWKN 158


>gi|22749327 ubiquitin-conjugating enzyme E2E 2 [Homo sapiens]
          Length = 201

 Score = 86.7 bits (213), Expect = 1e-17
 Identities = 50/151 (33%), Positives = 80/151 (52%), Gaps = 5/151 (3%)

Query: 10  QKKEEESAGGTKGSSKKASAAQLRIQKDINELNL--PKTCDISFSDPDDLLNFKLVIC-P 66
           Q K++E    +K ++K +++A+ RIQK++ E+ L  P  C       D++  ++  I  P
Sbjct: 37  QPKKKEGKISSKTAAKLSTSAK-RIQKELAEITLDPPPNCSAG-PKGDNIYEWRSTILGP 94

Query: 67  DEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTIN 126
               Y+ G F         YP  PPKV   T +YH NI+ +G +CL+IL+++W P LTI+
Sbjct: 95  PGSVYEGGVFFLDITFSPDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTIS 154

Query: 127 SIIYGLQYLFLEPNPEDPLNKEAAEVLQNNR 157
            ++  +  L  + NP DPL    A     NR
Sbjct: 155 KVLLSICSLLTDCNPADPLVGSIATQYMTNR 185


>gi|33359694 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]
          Length = 207

 Score = 86.3 bits (212), Expect = 1e-17
 Identities = 52/155 (33%), Positives = 77/155 (49%), Gaps = 7/155 (4%)

Query: 6   SLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNL--PKTCDISFSDPDDLLNFKLV 63
           S  QQKK  + +  T   + K S +  RIQK++ E+ L  P  C       D++  ++  
Sbjct: 41  SATQQKKNTKLSSKT---TAKLSTSAKRIQKELAEITLDPPPNCSAG-PKGDNIYEWRST 96

Query: 64  IC-PDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPV 122
           I  P    Y+ G F         YP  PPKV   T +YH NI+ +G +CL+IL+++W P 
Sbjct: 97  ILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPA 156

Query: 123 LTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNR 157
           LTI+ ++  +  L  + NP DPL    A     NR
Sbjct: 157 LTISKVLLSICSLLTDCNPADPLVGSIATQYLTNR 191


>gi|5454146 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]
          Length = 207

 Score = 86.3 bits (212), Expect = 1e-17
 Identities = 52/155 (33%), Positives = 77/155 (49%), Gaps = 7/155 (4%)

Query: 6   SLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNL--PKTCDISFSDPDDLLNFKLV 63
           S  QQKK  + +  T   + K S +  RIQK++ E+ L  P  C       D++  ++  
Sbjct: 41  SATQQKKNTKLSSKT---TAKLSTSAKRIQKELAEITLDPPPNCSAG-PKGDNIYEWRST 96

Query: 64  IC-PDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPV 122
           I  P    Y+ G F         YP  PPKV   T +YH NI+ +G +CL+IL+++W P 
Sbjct: 97  ILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPA 156

Query: 123 LTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNR 157
           LTI+ ++  +  L  + NP DPL    A     NR
Sbjct: 157 LTISKVLLSICSLLTDCNPADPLVGSIATQYLTNR 191


>gi|4507779 ubiquitin-conjugating enzyme E2E 1 isoform 1 [Homo
           sapiens]
          Length = 193

 Score = 85.1 bits (209), Expect = 3e-17
 Identities = 49/149 (32%), Positives = 75/149 (50%), Gaps = 4/149 (2%)

Query: 12  KEEESAGGTKGSSKKASAAQLRIQKDINELNL--PKTCDISFSDPDDLLNFKLVIC-PDE 68
           K++ES      +SK  S +  RIQK++ ++ L  P  C       D++  ++  I  P  
Sbjct: 30  KKKESKVSMSKNSKLLSTSAKRIQKELADITLDPPPNCSAG-PKGDNIYEWRSTILGPPG 88

Query: 69  GFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSI 128
             Y+ G F         YP  PPKV   T +YH NI+ +G +CL+IL+++W P LTI+ +
Sbjct: 89  SVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKV 148

Query: 129 IYGLQYLFLEPNPEDPLNKEAAEVLQNNR 157
           +  +  L  + NP DPL    A     NR
Sbjct: 149 LLSICSLLTDCNPADPLVGSIATQYMTNR 177


>gi|4507789 ubiquitin-conjugating enzyme E2L 3 isoform 1 [Homo
           sapiens]
          Length = 154

 Score = 84.3 bits (207), Expect = 5e-17
 Identities = 48/143 (33%), Positives = 73/143 (51%), Gaps = 9/143 (6%)

Query: 29  AAQLRIQKDINELNLPKTCDISFS-----DPDDLLNFKLVICPDEGFYKSGKFVFSFKVG 83
           AA  R+ K++ E+   + C +        D  +LL ++ +I PD   Y  G F       
Sbjct: 2   AASRRLMKELEEI---RKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFP 58

Query: 84  QGYPHDPPKVKCETMVYHPNIDLEGNVCLNIL-REDWKPVLTINSIIYGLQYLFLEPNPE 142
             YP  PPK+  +T +YHPNID +G VCL ++  E+WKP    + +I  L  L  +P PE
Sbjct: 59  AEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPE 118

Query: 143 DPLNKEAAEVLQNNRRLFEQNVQ 165
            PL  + AE    +R+ F +N +
Sbjct: 119 HPLRADLAEEYSKDRKKFCKNAE 141


>gi|32967289 ubiquitin-conjugating enzyme E2C isoform 4 [Homo
           sapiens]
          Length = 140

 Score = 82.0 bits (201), Expect = 3e-16
 Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 1/107 (0%)

Query: 50  SFSDPDDLLNFKLVICPDEG-FYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEG 108
           +F + D+L  +   I    G  Y+  ++  S +   GYP++ P VK  T  YHPN+D +G
Sbjct: 13  AFPESDNLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQG 72

Query: 109 NVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQN 155
           N+CL+IL+E W  +  + +I+  +Q L  EPN + PLN  AAE+ +N
Sbjct: 73  NICLDILKEKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKN 119


>gi|32967287 ubiquitin-conjugating enzyme E2C isoform 4 [Homo
           sapiens]
          Length = 140

 Score = 82.0 bits (201), Expect = 3e-16
 Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 1/107 (0%)

Query: 50  SFSDPDDLLNFKLVICPDEG-FYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEG 108
           +F + D+L  +   I    G  Y+  ++  S +   GYP++ P VK  T  YHPN+D +G
Sbjct: 13  AFPESDNLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQG 72

Query: 109 NVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQN 155
           N+CL+IL+E W  +  + +I+  +Q L  EPN + PLN  AAE+ +N
Sbjct: 73  NICLDILKEKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKN 119


>gi|4507793 ubiquitin-conjugating enzyme E2N [Homo sapiens]
          Length = 152

 Score = 81.6 bits (200), Expect = 3e-16
 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 1/105 (0%)

Query: 53  DPDDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVC 111
           D  +   F +VI  P +  ++ G F     + + YP   PKV+  T +YHPN+D  G +C
Sbjct: 28  DESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRIC 87

Query: 112 LNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNN 156
           L+IL++ W P L I +++  +Q L   PNP+DPL  + AE  + N
Sbjct: 88  LDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTN 132


>gi|32967285 ubiquitin-conjugating enzyme E2C isoform 3 [Homo
           sapiens]
          Length = 150

 Score = 81.3 bits (199), Expect = 4e-16
 Identities = 35/85 (41%), Positives = 54/85 (63%)

Query: 71  YKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIY 130
           Y+  ++  S +   GYP++ P VK  T  YHPN+D +GN+CL+IL+E W  +  + +I+ 
Sbjct: 45  YEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKEKWSALYDVRTILL 104

Query: 131 GLQYLFLEPNPEDPLNKEAAEVLQN 155
            +Q L  EPN + PLN  AAE+ +N
Sbjct: 105 SIQSLLGEPNIDSPLNTHAAELWKN 129


>gi|35494003 ubiquitin-conjugating enzyme E2I [Homo sapiens]
          Length = 158

 Score = 80.5 bits (197), Expect = 7e-16
 Identities = 43/113 (38%), Positives = 63/113 (55%), Gaps = 3/113 (2%)

Query: 56  DLLNFKLVICPDEGF-YKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNI 114
           +L+N++  I   +G  ++ G F         YP  PPK K E  ++HPN+   G VCL+I
Sbjct: 37  NLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSI 96

Query: 115 LRED--WKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQ 165
           L ED  W+P +TI  I+ G+Q L  EPN +DP   EA  +   NR  +E+ V+
Sbjct: 97  LEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVR 149


>gi|35493996 ubiquitin-conjugating enzyme E2I [Homo sapiens]
          Length = 158

 Score = 80.5 bits (197), Expect = 7e-16
 Identities = 43/113 (38%), Positives = 63/113 (55%), Gaps = 3/113 (2%)

Query: 56  DLLNFKLVICPDEGF-YKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNI 114
           +L+N++  I   +G  ++ G F         YP  PPK K E  ++HPN+   G VCL+I
Sbjct: 37  NLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSI 96

Query: 115 LRED--WKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQ 165
           L ED  W+P +TI  I+ G+Q L  EPN +DP   EA  +   NR  +E+ V+
Sbjct: 97  LEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVR 149


>gi|35493987 ubiquitin-conjugating enzyme E2I [Homo sapiens]
          Length = 158

 Score = 80.5 bits (197), Expect = 7e-16
 Identities = 43/113 (38%), Positives = 63/113 (55%), Gaps = 3/113 (2%)

Query: 56  DLLNFKLVICPDEGF-YKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNI 114
           +L+N++  I   +G  ++ G F         YP  PPK K E  ++HPN+   G VCL+I
Sbjct: 37  NLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSI 96

Query: 115 LRED--WKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQ 165
           L ED  W+P +TI  I+ G+Q L  EPN +DP   EA  +   NR  +E+ V+
Sbjct: 97  LEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVR 149


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.138    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,538,272
Number of Sequences: 37866
Number of extensions: 336367
Number of successful extensions: 933
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 847
Number of HSP's gapped (non-prelim): 68
length of query: 183
length of database: 18,247,518
effective HSP length: 96
effective length of query: 87
effective length of database: 14,612,382
effective search space: 1271277234
effective search space used: 1271277234
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.