Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help
Name: SPARC Sequence: fasta or formatted (303aa) NCBI GI: 4507171
Description:

secreted protein, acidic, cysteine-rich

Referenced in:

Bone and Related Tissues

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.9         18           2
 C cysteine            5.0         15           1
 D aspartate           7.6         23           2
 E glutamate          11.2         34           3
 F phenylalanine       4.6         14           2
 G glycine             4.6         14           1
 H histidine           4.0         12           2
 I isoleucine          4.0         12           1
 K lysine              6.6         20           2
 L leucine             9.6         29           2
 M methionine          1.7          5           1
 N asparagine          4.6         14           2
 P proline             5.9         18           2
 Q glutamine           3.3         10           2
 R arginine            3.3         10           1
 S serine              2.3          7           2
 T threonine           5.6         17           2
 V valine              6.6         20           2
 W tryptophan          1.3          4           1
 Y tyrosine            2.3          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   secreted protein, acidic, cysteine-rich 
SPARCL1               0.482   SPARC-like 1 
SPARCL1               0.482   SPARC-like 1 
SPOCK3                0.055   testican 3 isoform 2 
SPOCK3                0.053   testican 3 isoform 1 
SPOCK2                0.048   sparc/osteonectin, cwcv and kazal-like domains proteo...
FST                   0.044   follistatin isoform FST317 precursor 
FST                   0.044   follistatin isoform FST344 precursor 
SPOCK1                0.042   sparc/osteonectin, cwcv and kazal-like domains proteo...
FSTL3                 0.037   follistatin-like 3 glycoprotein precursor 
SMOC2                 0.035   SPARC related modular calcium binding 2 
SMOC1                 0.034   secreted modular calcium-binding protein 1 isoform 1...
SMOC1                 0.034   secreted modular calcium-binding protein 1 isoform 2...
AGRN                  0.032   agrin 
FSTL1                 0.031   follistatin-like 1 precursor 
NOTCH3                0.023   Notch homolog 3 
TMEFF2                0.021   transmembrane protein with EGF-like and two follista...
SNED1                 0.018   6720455I24Rik homolog 
EYS                   0.016   eyes shut homolog isoform 1 
NOTCH1                0.016   notch1 preproprotein 
SLIT2                 0.016   slit homolog 2 
LOC100290309          0.013   PREDICTED: hypothetical protein XP_002348012 
FCGBP                 0.013   Fc fragment of IgG binding protein 
SCUBE2                0.011   CEGP1 protein 
RREB1                 0.011   ras responsive element binding protein 1 isoform 2 [...
RREB1                 0.011   ras responsive element binding protein 1 isoform 1 [...
SCARF1                0.011   scavenger receptor class F, member 1 isoform 3 precu...
SCARF1                0.011   scavenger receptor class F, member 1 isoform 1 precu...
TMEFF1                0.011   transmembrane protein with EGF-like and two follista...
LCP1                  0.010   L-plastin 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press