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Search of human proteins with 4506449
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506449 RNA binding motif, single stranded interacting
protein 2 [Homo sapiens]
(407 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506449 RNA binding motif, single stranded interacting protei... 824 0.0
gi|51317351 RNA binding motif, single stranded interacting prote... 554 e-158
gi|4506447 RNA binding motif, single stranded interacting protei... 549 e-156
gi|8400718 RNA binding motif, single stranded interacting protei... 546 e-155
gi|51317355 RNA binding motif, single stranded interacting prote... 543 e-155
gi|51317353 RNA binding motif, single stranded interacting prote... 516 e-146
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 113 4e-25
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 107 2e-23
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 107 2e-23
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 107 3e-23
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 107 3e-23
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 106 4e-23
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 104 2e-22
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 104 2e-22
gi|38201714 ELAV-like 1 [Homo sapiens] 103 3e-22
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 88 2e-17
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 85 1e-16
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 79 6e-15
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 79 6e-15
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 79 6e-15
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 77 2e-14
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 76 5e-14
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 75 1e-13
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 71 2e-12
gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa... 71 2e-12
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 71 2e-12
gi|71164894 trinucleotide repeat containing 4 [Homo sapiens] 70 4e-12
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 64 2e-10
gi|134152680 CUG triplet repeat, RNA binding protein 2 isoform 2... 64 3e-10
gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3 ... 63 4e-10
>gi|4506449 RNA binding motif, single stranded interacting protein 2
[Homo sapiens]
Length = 407
Score = 824 bits (2128), Expect = 0.0
Identities = 407/407 (100%), Positives = 407/407 (100%)
Query: 1 MLLSVTSRPGISTFGYNRNNKKPYVSLAQQMAPPSPSNSTPNSSSGSNGNDQLSKTNLYI 60
MLLSVTSRPGISTFGYNRNNKKPYVSLAQQMAPPSPSNSTPNSSSGSNGNDQLSKTNLYI
Sbjct: 1 MLLSVTSRPGISTFGYNRNNKKPYVSLAQQMAPPSPSNSTPNSSSGSNGNDQLSKTNLYI 60
Query: 61 RGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKAS 120
RGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKAS
Sbjct: 61 RGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKAS 120
Query: 121 GVQAQMAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFA 180
GVQAQMAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFA
Sbjct: 121 GVQAQMAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFA 180
Query: 181 RMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPR 240
RMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPR
Sbjct: 181 RMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPR 240
Query: 241 NADMGVMALTYDPTTALQNGFYPAPYNITPNRMLAQSALSPYLSSPVSSYQRVTQTSPLQ 300
NADMGVMALTYDPTTALQNGFYPAPYNITPNRMLAQSALSPYLSSPVSSYQRVTQTSPLQ
Sbjct: 241 NADMGVMALTYDPTTALQNGFYPAPYNITPNRMLAQSALSPYLSSPVSSYQRVTQTSPLQ 300
Query: 301 VPNPSWMHHHSYLMQPSGSVLTPGMDHPISLQPASMMGPLTQQLGHLSLSSTGTYMPTAA 360
VPNPSWMHHHSYLMQPSGSVLTPGMDHPISLQPASMMGPLTQQLGHLSLSSTGTYMPTAA
Sbjct: 301 VPNPSWMHHHSYLMQPSGSVLTPGMDHPISLQPASMMGPLTQQLGHLSLSSTGTYMPTAA 360
Query: 361 AMQGAYISQYTPVPSSSVSVEESSGQQNQVAVDAPSEHGVYSFQFNK 407
AMQGAYISQYTPVPSSSVSVEESSGQQNQVAVDAPSEHGVYSFQFNK
Sbjct: 361 AMQGAYISQYTPVPSSSVSVEESSGQQNQVAVDAPSEHGVYSFQFNK 407
>gi|51317351 RNA binding motif, single stranded interacting protein
3 isoform 2 [Homo sapiens]
Length = 420
Score = 554 bits (1427), Expect = e-158
Identities = 275/406 (67%), Positives = 325/406 (80%), Gaps = 29/406 (7%)
Query: 21 KKPYVSLAQQMAPPSPS-NSTPNSSSGSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPY 79
K+ Y MAPPSPS NS+ N+SS ++ +QLSKTNLYIRGL PGTTDQDL+KLCQPY
Sbjct: 25 KQSYAPAPHPMAPPSPSTNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPY 84
Query: 80 GKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDPTNLYI 139
GKIVSTKAILDK TN+CKGYGFVDFDSP+AAQKAV +LKA+GVQAQMAKQQEQDPTNLYI
Sbjct: 85 GKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYI 144
Query: 140 SNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKY 199
SNLP+SMDEQELE MLKPFG VISTRILRD +G SRGVGFARMESTEKCE +I HFNGKY
Sbjct: 145 SNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKY 204
Query: 200 IKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPTTALQN 259
+KTPPG+PAPS+PLLCKFADGG KKRQNQ K+ QNGR WPR + G MALTYDPT A+QN
Sbjct: 205 LKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAG-MALTYDPTAAIQN 263
Query: 260 GFYPAPYNITPNRMLAQSALSPYL-SSPVSSYQRVTQTSPLQVPNPSWMHHHSYLMQPSG 318
GFY +PY+I NRM+ Q++++P++ +SPVS+Y QV + SWM H Y+MQP+G
Sbjct: 264 GFYSSPYSIATNRMIPQTSITPFIAASPVSTY---------QVQSTSWMPHPPYVMQPTG 314
Query: 319 SVLTPGMDHPISLQPASMMGPLTQQLGHLSLSSTGTYMPTAAAMQGAYISQYTPVPSSSV 378
+V+TP MDHP+S+QPA+MMGPLTQQ+ HLSL +TGTYM AA MQG YI QYTPVP ++V
Sbjct: 315 AVITPTMDHPMSMQPANMMGPLTQQMNHLSLGTTGTYMTAAAPMQGTYIPQYTPVPPTAV 374
Query: 379 SVE----------------ESSGQQNQVAVDAPSEHG-VYSFQFNK 407
S+E ++SGQQ Q+AVD +EH YS+Q +K
Sbjct: 375 SIEGVVADTSPQTVAPSSQDTSGQQQQIAVDTSNEHAPAYSYQQSK 420
>gi|4506447 RNA binding motif, single stranded interacting protein 1
isoform c [Homo sapiens]
Length = 403
Score = 549 bits (1414), Expect = e-156
Identities = 275/384 (71%), Positives = 320/384 (83%), Gaps = 15/384 (3%)
Query: 28 AQQMAPPSPSNSTPNSSSGSNGN---DQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVS 84
A MAPPSPS ++ N++S S+ N DQLSKTNLYIRGL P TTDQDLVKLCQPYGKIVS
Sbjct: 31 AHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVS 90
Query: 85 TKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDPTNLYISNLPL 144
TKAILDKTTNKCKGYGFVDFDSP+AAQKAV+ALKASGVQAQMAKQQEQDPTNLYISNLPL
Sbjct: 91 TKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNLYISNLPL 150
Query: 145 SMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPP 204
SMDEQELE MLKPFGQVISTRILRD+SGTSRGVGFARMESTEKCEA+I HFNGK+IKTPP
Sbjct: 151 SMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPP 210
Query: 205 GVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPTT-ALQNGFYP 263
GV AP++PLLCKFADGG KKRQN K++ NGR W R + G M LTYDPTT A+QNGFYP
Sbjct: 211 GVSAPTEPLLCKFADGGQKKRQNPNKYIPNGRPWHREGEAG-MTLTYDPTTAAIQNGFYP 269
Query: 264 APYNITPNRMLAQSALSPYLSSPVSSYQRVTQTSPLQVPNPSWMHHHSYLMQPSGSVLTP 323
+PY+I NRM+ Q++++PY++SPVS+Y QV +PSWM Y++Q G+VLTP
Sbjct: 270 SPYSIATNRMITQTSITPYIASPVSAY---------QVQSPSWMQPQPYILQHPGAVLTP 320
Query: 324 GMDHPISLQPASMMGPLTQQLGHLSLSSTGTYMPTAAAMQGAYISQYTPVPSSSVSVEES 383
M+H +SLQPASM+ PL QQ+ HLSL STGTYMP +AMQGAY+ QY + +++V VEE+
Sbjct: 321 SMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATSAMQGAYLPQYAHMQTTAVPVEEA 380
Query: 384 SGQQNQVAVDAPSEHGVYSFQFNK 407
SGQQ QVAV+ ++H Y+FQ NK
Sbjct: 381 SGQQ-QVAVETSNDHSPYTFQPNK 403
>gi|8400718 RNA binding motif, single stranded interacting protein 1
isoform a [Homo sapiens]
Length = 406
Score = 546 bits (1408), Expect = e-155
Identities = 274/386 (70%), Positives = 321/386 (83%), Gaps = 16/386 (4%)
Query: 28 AQQMAPPSPSNSTPNSSSGSNGN---DQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVS 84
A MAPPSPS ++ N++S S+ N DQLSKTNLYIRGL P TTDQDLVKLCQPYGKIVS
Sbjct: 31 AHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVS 90
Query: 85 TKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDPTNLYISNLPL 144
TKAILDKTTNKCKGYGFVDFDSP+AAQKAV+ALKASGVQAQMAKQQEQDPTNLYISNLPL
Sbjct: 91 TKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNLYISNLPL 150
Query: 145 SMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPP 204
SMDEQELE MLKPFGQVISTRILRD+SGTSRGVGFARMESTEKCEA+I HFNGK+IKTPP
Sbjct: 151 SMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPP 210
Query: 205 GVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGV--MALTYDPTT-ALQNGF 261
GV AP++PLLCKFADGG KKRQN K++ NGR W R ++ + M LTYDPTT A+QNGF
Sbjct: 211 GVSAPTEPLLCKFADGGQKKRQNPNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAIQNGF 270
Query: 262 YPAPYNITPNRMLAQSALSPYLSSPVSSYQRVTQTSPLQVPNPSWMHHHSYLMQPSGSVL 321
YP+PY+I NRM+ Q++++PY++SPVS+Y QV +PSWM Y++Q G+VL
Sbjct: 271 YPSPYSIATNRMITQTSITPYIASPVSAY---------QVQSPSWMQPQPYILQHPGAVL 321
Query: 322 TPGMDHPISLQPASMMGPLTQQLGHLSLSSTGTYMPTAAAMQGAYISQYTPVPSSSVSVE 381
TP M+H +SLQPASM+ PL QQ+ HLSL STGTYMP +AMQGAY+ QY + +++V VE
Sbjct: 322 TPSMEHTMSLQPASMISPLAQQMSHLSLGSTGTYMPATSAMQGAYLPQYAHMQTTAVPVE 381
Query: 382 ESSGQQNQVAVDAPSEHGVYSFQFNK 407
E+SGQQ QVAV+ ++H Y+FQ NK
Sbjct: 382 EASGQQ-QVAVETSNDHSPYTFQPNK 406
>gi|51317355 RNA binding motif, single stranded interacting protein
3 isoform 1 [Homo sapiens]
Length = 437
Score = 543 bits (1400), Expect = e-155
Identities = 275/422 (65%), Positives = 325/422 (77%), Gaps = 45/422 (10%)
Query: 21 KKPYVSLAQQMAPPSPS-NSTPNSSSGSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPY 79
K+ Y MAPPSPS NS+ N+SS ++ +QLSKTNLYIRGL PGTTDQDL+KLCQPY
Sbjct: 25 KQSYAPAPHPMAPPSPSTNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPY 84
Query: 80 GKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDPTNLYI 139
GKIVSTKAILDK TN+CKGYGFVDFDSP+AAQKAV +LKA+GVQAQMAKQQEQDPTNLYI
Sbjct: 85 GKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYI 144
Query: 140 SNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKY 199
SNLP+SMDEQELE MLKPFG VISTRILRD +G SRGVGFARMESTEKCE +I HFNGKY
Sbjct: 145 SNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKY 204
Query: 200 IKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPTTALQN 259
+KTPPG+PAPS+PLLCKFADGG KKRQNQ K+ QNGR WPR + G MALTYDPT A+QN
Sbjct: 205 LKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAG-MALTYDPTAAIQN 263
Query: 260 GFYPAPYNITPNRMLAQSALSPYL-SSPVSSYQRVTQTSPLQVPNPSWMHHHSYLMQPSG 318
GFY +PY+I NRM+ Q++++P++ +SPVS+Y QV + SWM H Y+MQP+G
Sbjct: 264 GFYSSPYSIATNRMIPQTSITPFIAASPVSTY---------QVQSTSWMPHPPYVMQPTG 314
Query: 319 SVLTPGMDHPISLQPASMMGPLTQQLGHLSLSSTGT----------------YMPTAAAM 362
+V+TP MDHP+S+QPA+MMGPLTQQ+ HLSL +TGT YM AA M
Sbjct: 315 AVITPTMDHPMSMQPANMMGPLTQQMNHLSLGTTGTIQSQDRIMILHQLLCQYMTAAAPM 374
Query: 363 QGAYISQYTPVPSSSVSVE----------------ESSGQQNQVAVDAPSEHG-VYSFQF 405
QG YI QYTPVP ++VS+E ++SGQQ Q+AVD +EH YS+Q
Sbjct: 375 QGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDTSGQQQQIAVDTSNEHAPAYSYQQ 434
Query: 406 NK 407
+K
Sbjct: 435 SK 436
>gi|51317353 RNA binding motif, single stranded interacting protein
3 isoform 3 [Homo sapiens]
Length = 419
Score = 516 bits (1330), Expect = e-146
Identities = 266/421 (63%), Positives = 312/421 (74%), Gaps = 62/421 (14%)
Query: 22 KPYVSLAQQMAPPSPS-NSTPNSSSGSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYG 80
K Y MAPPSPS NS+ N+SS ++ +QLSKTNLYIRGL PGTTDQDL+KLCQPYG
Sbjct: 25 KSYAPAPHPMAPPSPSTNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYG 84
Query: 81 KIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDPTNLYIS 140
KIVSTKAILDK TN+CKGYGFVDFDSP+AAQKAV +LKA+GVQAQMAKQQEQDPTNLYIS
Sbjct: 85 KIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYIS 144
Query: 141 NLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYI 200
NLP+SMDEQELE MLKPFG VISTRILRD +G SRGVGFARMESTEKCE +I HFNGKY+
Sbjct: 145 NLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYL 204
Query: 201 KTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPTTALQNG 260
KTPPG+PAPS+PLLCKFADGG KKRQNQ K+ QNGR WPR + G MALTYDPT A+QNG
Sbjct: 205 KTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAG-MALTYDPTAAIQNG 263
Query: 261 FYPAPYNITPNRMLAQSALSPYL-SSPVSSYQRVTQTSPLQVPNPSWMHHHSYLMQPSGS 319
FY +PY+I NRM+ Q++++P++ +SPVS+YQ G+
Sbjct: 264 FYSSPYSIATNRMIPQTSITPFIAASPVSTYQ--------------------------GA 297
Query: 320 VLTPGMDHPISLQPASMMGPLTQQLGHLSLSSTGT----------------YMPTAAAMQ 363
V+TP MDHP+S+QPA+MMGPLTQQ+ HLSL +TGT YM AA MQ
Sbjct: 298 VITPTMDHPMSMQPANMMGPLTQQMNHLSLGTTGTIQSQDRIMILHQLLCQYMTAAAPMQ 357
Query: 364 GAYISQYTPVPSSSVSVE----------------ESSGQQNQVAVDAPSEHG-VYSFQFN 406
G YI QYTPVP ++VS+E ++SGQQ Q+AVD +EH YS+Q +
Sbjct: 358 GTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDTSGQQQQIAVDTSNEHAPAYSYQQS 417
Query: 407 K 407
K
Sbjct: 418 K 418
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 113 bits (282), Expect = 4e-25
Identities = 71/194 (36%), Positives = 106/194 (54%), Gaps = 15/194 (7%)
Query: 43 SSSGSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFV 102
SS +GN + SKTNL + L T ++L L G+I S K + DK T + GYGFV
Sbjct: 26 SSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFV 85
Query: 103 DFDSPSAAQKAVTALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDEQELEGML 155
++ P A+KA+ L +Q + K P+ NLY+S LP +M ++ELE +
Sbjct: 86 NYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLF 145
Query: 156 KPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLL 214
+G++I++RIL D +G SRGVGF R + + E I NG + PPG ++P+
Sbjct: 146 SQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG---QKPPGA---TEPIT 199
Query: 215 CKFADGGPKKRQNQ 228
KFA+ P ++ NQ
Sbjct: 200 VKFAN-NPSQKTNQ 212
Score = 45.4 bits (106), Expect = 9e-05
Identities = 20/60 (33%), Positives = 33/60 (55%)
Query: 58 LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117
+++ L P + L ++ P+G + + K I D TNKCKG+GFV + A A+ +L
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Score = 37.0 bits (84), Expect = 0.032
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 137 LYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHF 195
+++ NL DE L M PFG V + +++RD + +G GF M + ++ I
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 196 NG 197
NG
Sbjct: 338 NG 339
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 107 bits (267), Expect = 2e-23
Identities = 73/231 (31%), Positives = 113/231 (48%), Gaps = 25/231 (10%)
Query: 21 KKPYVSLAQQMAPPSPSNSTPNSSSGSNGN----------DQLSKTNLYIRGLQPGTTDQ 70
K +S + P+++T N S +N N SKTNL + L T +
Sbjct: 4 KNQIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQE 63
Query: 71 DLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQ 130
+ L G+I S K + DK T + GYGFV++ P A+KA+ L +Q + K
Sbjct: 64 EFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVS 123
Query: 131 EQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARM 182
P+ NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R
Sbjct: 124 YARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRF 183
Query: 183 ESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQ 233
+ + E I NG + P G ++P+ KFA+ P ++ +Q Q
Sbjct: 184 DKRIEAEEAIKGLNG---QKPSGA---TEPITVKFAN-NPSQKSSQALLSQ 227
Score = 45.8 bits (107), Expect = 7e-05
Identities = 21/60 (35%), Positives = 34/60 (56%)
Query: 58 LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117
+++ L P + + L +L P+G + + K I D TNKCKG+GFV + A A+ +L
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Score = 35.4 bits (80), Expect = 0.093
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 137 LYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHF 195
+++ NL DE L + PFG V + +++RD + +G GF M + ++ I
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 196 NG 197
NG
Sbjct: 348 NG 349
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 107 bits (267), Expect = 2e-23
Identities = 74/235 (31%), Positives = 115/235 (48%), Gaps = 25/235 (10%)
Query: 17 NRNNKKPYVSLAQQMAPPSPSNSTPNSSSGSNGN----------DQLSKTNLYIRGLQPG 66
+RN +S + P+++T N S +N N SKTNL + L
Sbjct: 14 SRNCSFMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQN 73
Query: 67 TTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQM 126
T ++ L G+I S K + DK T + GYGFV++ P A+KA+ L +Q +
Sbjct: 74 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 133
Query: 127 AKQQEQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVG 178
K P+ NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVG
Sbjct: 134 IKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVG 193
Query: 179 FARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQ 233
F R + + E I NG + P G ++P+ KFA+ P ++ +Q Q
Sbjct: 194 FIRFDKRIEAEEAIKGLNG---QKPSGA---TEPITVKFAN-NPSQKSSQALLSQ 241
Score = 45.8 bits (107), Expect = 7e-05
Identities = 21/60 (35%), Positives = 34/60 (56%)
Query: 58 LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117
+++ L P + + L +L P+G + + K I D TNKCKG+GFV + A A+ +L
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Score = 35.4 bits (80), Expect = 0.093
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 137 LYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHF 195
+++ NL DE L + PFG V + +++RD + +G GF M + ++ I
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 196 NG 197
NG
Sbjct: 362 NG 363
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 107 bits (266), Expect = 3e-23
Identities = 73/230 (31%), Positives = 114/230 (49%), Gaps = 28/230 (12%)
Query: 25 VSLAQQMAPPSPSNSTPNSSSGSNGNDQL-------------SKTNLYIRGLQPGTTDQD 71
V + M P + T N+S+G + N++ SKTNL + L T ++
Sbjct: 2 VMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEE 61
Query: 72 LVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQE 131
L G+I S K + DK T + GYGFV++ P A+KA+ L +Q + K
Sbjct: 62 FRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSY 121
Query: 132 QDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARME 183
P+ NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R +
Sbjct: 122 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 181
Query: 184 STEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQ 233
+ E I NG + P G ++P+ KFA+ P ++ +Q Q
Sbjct: 182 KRIEAEEAIKGLNG---QKPSGA---TEPITVKFAN-NPSQKSSQALLSQ 224
Score = 45.8 bits (107), Expect = 7e-05
Identities = 21/60 (35%), Positives = 34/60 (56%)
Query: 58 LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117
+++ L P + + L +L P+G + + K I D TNKCKG+GFV + A A+ +L
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Score = 35.4 bits (80), Expect = 0.093
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 137 LYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHF 195
+++ NL DE L + PFG V + +++RD + +G GF M + ++ I
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Query: 196 NG 197
NG
Sbjct: 359 NG 360
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 107 bits (266), Expect = 3e-23
Identities = 73/230 (31%), Positives = 114/230 (49%), Gaps = 28/230 (12%)
Query: 25 VSLAQQMAPPSPSNSTPNSSSGSNGNDQL-------------SKTNLYIRGLQPGTTDQD 71
V + M P + T N+S+G + N++ SKTNL + L T ++
Sbjct: 2 VMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEE 61
Query: 72 LVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQE 131
L G+I S K + DK T + GYGFV++ P A+KA+ L +Q + K
Sbjct: 62 FRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSY 121
Query: 132 QDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARME 183
P+ NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R +
Sbjct: 122 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 181
Query: 184 STEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQ 233
+ E I NG + P G ++P+ KFA+ P ++ +Q Q
Sbjct: 182 KRIEAEEAIKGLNG---QKPSGA---TEPITVKFAN-NPSQKSSQALLSQ 224
Score = 45.8 bits (107), Expect = 7e-05
Identities = 21/60 (35%), Positives = 34/60 (56%)
Query: 58 LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117
+++ L P + + L +L P+G + + K I D TNKCKG+GFV + A A+ +L
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Score = 35.4 bits (80), Expect = 0.093
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 137 LYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHF 195
+++ NL DE L + PFG V + +++RD + +G GF M + ++ I
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 196 NG 197
NG
Sbjct: 345 NG 346
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 106 bits (264), Expect = 4e-23
Identities = 72/227 (31%), Positives = 112/227 (49%), Gaps = 25/227 (11%)
Query: 25 VSLAQQMAPPSPSNSTPNSSSGSNGN----------DQLSKTNLYIRGLQPGTTDQDLVK 74
+S + P+++T N S +N N SKTNL + L T ++
Sbjct: 5 ISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRS 64
Query: 75 LCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDP 134
L G+I S K + DK T + GYGFV++ P A+KA+ L +Q + K P
Sbjct: 65 LFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARP 124
Query: 135 T-------NLYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTE 186
+ NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R +
Sbjct: 125 SSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRI 184
Query: 187 KCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQ 233
+ E I NG + P G ++P+ KFA+ P ++ +Q Q
Sbjct: 185 EAEEAIKGLNG---QKPSGA---TEPITVKFAN-NPSQKSSQALLSQ 224
Score = 45.8 bits (107), Expect = 7e-05
Identities = 21/60 (35%), Positives = 34/60 (56%)
Query: 58 LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117
+++ L P + + L +L P+G + + K I D TNKCKG+GFV + A A+ +L
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Score = 35.4 bits (80), Expect = 0.093
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 137 LYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHF 195
+++ NL DE L + PFG V + +++RD + +G GF M + ++ I
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 196 NG 197
NG
Sbjct: 345 NG 346
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 104 bits (259), Expect = 2e-22
Identities = 65/187 (34%), Positives = 97/187 (51%), Gaps = 14/187 (7%)
Query: 46 GSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFD 105
G+NG SKTNL + L T + L G I S K + DK T + GYGFV++
Sbjct: 29 GTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYS 88
Query: 106 SPSAAQKAVTALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDEQELEGMLKPF 158
P+ A KA+ L +Q + K P+ NLY+S LP +M ++E+E + +
Sbjct: 89 DPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQY 148
Query: 159 GQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKF 217
G++I++RIL D +G SRGVGF R + + E I NG + P G ++P+ KF
Sbjct: 149 GRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG---QKPLGA---AEPITVKF 202
Query: 218 ADGGPKK 224
A+ +K
Sbjct: 203 ANNPSQK 209
Score = 49.7 bits (117), Expect = 5e-06
Identities = 28/96 (29%), Positives = 48/96 (50%)
Query: 22 KPYVSLAQQMAPPSPSNSTPNSSSGSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGK 81
K +SL + +P + + + G +G + +++ L P + L +L P+G
Sbjct: 250 KSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGA 309
Query: 82 IVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117
+ + K I D TTNKCKG+GFV + A A+ +L
Sbjct: 310 VTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Score = 38.1 bits (87), Expect = 0.014
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 137 LYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHF 195
+++ NL DE L + PFG V + +++RD T+ +G GF M + ++ I
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 196 NG 197
NG
Sbjct: 346 NG 347
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 104 bits (259), Expect = 2e-22
Identities = 65/187 (34%), Positives = 97/187 (51%), Gaps = 14/187 (7%)
Query: 46 GSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFD 105
G+NG SKTNL + L T + L G I S K + DK T + GYGFV++
Sbjct: 29 GTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYS 88
Query: 106 SPSAAQKAVTALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDEQELEGMLKPF 158
P+ A KA+ L +Q + K P+ NLY+S LP +M ++E+E + +
Sbjct: 89 DPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQY 148
Query: 159 GQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKF 217
G++I++RIL D +G SRGVGF R + + E I NG + P G ++P+ KF
Sbjct: 149 GRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG---QKPLGA---AEPITVKF 202
Query: 218 ADGGPKK 224
A+ +K
Sbjct: 203 ANNPSQK 209
Score = 48.1 bits (113), Expect = 1e-05
Identities = 22/60 (36%), Positives = 34/60 (56%)
Query: 58 LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117
+++ L P + L +L P+G + + K I D TTNKCKG+GFV + A A+ +L
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Score = 38.1 bits (87), Expect = 0.014
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 137 LYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHF 195
+++ NL DE L + PFG V + +++RD T+ +G GF M + ++ I
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 196 NG 197
NG
Sbjct: 339 NG 340
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 103 bits (257), Expect = 3e-22
Identities = 64/183 (34%), Positives = 97/183 (53%), Gaps = 15/183 (8%)
Query: 53 LSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQK 112
+ +TNL + L T +L L G++ S K I DK GYGFV++ + A++
Sbjct: 17 IGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAER 76
Query: 113 AVTALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTR 165
A+ L +Q++ K P+ NLYIS LP +M ++++E M FG++I++R
Sbjct: 77 AINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSR 136
Query: 166 ILRD-TSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKK 224
+L D T+G SRGV F R + + E IT FNG PPG S+P+ KFA P +
Sbjct: 137 VLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG---HKPPG---SSEPITVKFA-ANPNQ 189
Query: 225 RQN 227
+N
Sbjct: 190 NKN 192
Score = 53.1 bits (126), Expect = 4e-07
Identities = 44/208 (21%), Positives = 80/208 (38%), Gaps = 60/208 (28%)
Query: 50 NDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSA 109
++ + NLYI GL T +D+ + +G+I++++ ++D+TT +G F+ FD S
Sbjct: 100 SEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSE 159
Query: 110 AQKAVTAL-------KASGVQAQMAKQQEQDPTNLYISNL-------------------- 142
A++A+T+ + + + A Q+ +S L
Sbjct: 160 AEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFR 219
Query: 143 --PLSMD------------------------------EQELEGMLKPFGQVISTRILRD- 169
P+ +D E L M PFG V + +++RD
Sbjct: 220 FSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDF 279
Query: 170 TSGTSRGVGFARMESTEKCEAIITHFNG 197
+ +G GF M + E+ I NG
Sbjct: 280 NTNKCKGFGFVTMTNYEEAAMAIASLNG 307
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 87.8 bits (216), Expect = 2e-17
Identities = 46/159 (28%), Positives = 84/159 (52%), Gaps = 17/159 (10%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
N++I+ L+ ++ L +G I+S K D+ + +G+GFV F++ AAQ+A+
Sbjct: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
Query: 117 LKASGVQ------AQMAKQQEQDP---------TNLYISNLPLSMDEQELEGMLKPFGQV 161
+ + ++E++ TN+Y+ NLP+ +DEQ L+ + FG++
Sbjct: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
Query: 162 ISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYI 200
+S +++RD SG SR GF E E+ + + H NGK +
Sbjct: 218 LSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEV 256
Score = 77.4 bits (189), Expect = 2e-14
Identities = 50/181 (27%), Positives = 84/181 (46%), Gaps = 27/181 (14%)
Query: 49 GNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPS 108
G L TN+Y++ L +Q L L +GK++S K + D + + + +GFV+F+
Sbjct: 184 GARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHS-RCFGFVNFEKHE 242
Query: 109 AAQKAVTALKASGVQAQMA-------------------KQQEQDP------TNLYISNLP 143
AQKAV + V ++ +Q +QD NLY+ NL
Sbjct: 243 EAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLD 302
Query: 144 LSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTP 203
S+D+ +L P+G + S +++ + G S+G GF S E+ +T NG+ + T
Sbjct: 303 DSIDDDKLRKEFSPYGVITSAKVMTE-GGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTK 361
Query: 204 P 204
P
Sbjct: 362 P 362
Score = 72.0 bits (175), Expect = 9e-13
Identities = 43/150 (28%), Positives = 73/150 (48%), Gaps = 10/150 (6%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
+LY+ L P T+ L + P G I+S + D T + GY +++F P+ A++A+
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
Query: 117 LKASGVQAQMAK--QQEQDP-------TNLYISNLPLSMDEQELEGMLKPFGQVISTRIL 167
+ ++ Q + ++DP N++I NL S+D + L FG ++S ++
Sbjct: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
Query: 168 RDTSGTSRGVGFARMESTEKCEAIITHFNG 197
D G SRG GF E+ E + I NG
Sbjct: 132 CDEHG-SRGFGFVHFETHEAAQQAINTMNG 160
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 85.1 bits (209), Expect = 1e-16
Identities = 91/382 (23%), Positives = 143/382 (37%), Gaps = 73/382 (19%)
Query: 56 TNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAV- 114
TN+YI+ D+ L L +G +S K + D++ K KG+GFV F+ AQKAV
Sbjct: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDES-GKSKGFGFVSFERHEDAQKAVD 249
Query: 115 ------------------------TALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQE 150
T LK Q + + NLY+ NL +D++
Sbjct: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
Query: 151 LEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPS 210
L PFG + S +++ + G S+G GF S E+ +T NG+ + T P A +
Sbjct: 310 LRKEFSPFGTITSAKVMME-GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALA 368
Query: 211 DPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPTTALQNGFYPAPYNITP 270
+K + Q N M MA + N + PAP +
Sbjct: 369 Q-----------RKEERQAHLT--------NQYMQRMASVRAVPNPVINPYQPAPPS--- 406
Query: 271 NRMLAQSALSPYLSSPVSSYQRVTQTSPLQV----PNPSW----MHHHSYLMQPSGSVLT 322
++++ + R P Q+ P+P W H + P G++
Sbjct: 407 ---------GYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMP-GAIRP 456
Query: 323 PGMDHPIS-LQPASMMGPLTQQLGHLSLSSTGTYMPTAAAMQGAYISQYTPVPSSSVSVE 381
P S ++PAS P ++ +ST T P AA A VP +
Sbjct: 457 AAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAG 516
Query: 382 ESSGQQN-----QVAVDAPSEH 398
+ QQ+ QV + P+ H
Sbjct: 517 VRNPQQHLNAQPQVTMQQPAVH 538
Score = 79.0 bits (193), Expect = 7e-15
Identities = 46/157 (29%), Positives = 79/157 (50%), Gaps = 17/157 (10%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
N++I+ L ++ L +G I+S K + D+ N KGYGFV F++ AA++A+
Sbjct: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
Query: 117 L--------KASGVQAQMAKQQE-------QDPTNLYISNLPLSMDEQELEGMLKPFGQV 161
+ K + + K++E ++ TN+YI N MD++ L+ + FG
Sbjct: 158 MNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPA 217
Query: 162 ISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGK 198
+S +++ D SG S+G GF E E + + NGK
Sbjct: 218 LSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGK 254
Score = 75.9 bits (185), Expect = 6e-14
Identities = 43/150 (28%), Positives = 76/150 (50%), Gaps = 10/150 (6%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
+LY+ L P T+ L + P G I+S + D T + GY +V+F P+ A++A+
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 117 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRIL 167
+ ++ + + ++DP+ N++I NL S+D + L FG ++S +++
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 168 RDTSGTSRGVGFARMESTEKCEAIITHFNG 197
D +G S+G GF E+ E E I NG
Sbjct: 132 CDENG-SKGYGFVHFETQEAAERAIEKMNG 160
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 79.3 bits (194), Expect = 6e-15
Identities = 70/276 (25%), Positives = 110/276 (39%), Gaps = 54/276 (19%)
Query: 56 TNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVT 115
TN+YI+ D+ L +L +GK +S K + D K KG+GFV ++ A KAV
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVE 249
Query: 116 ALKASGV----------------QAQMAKQQEQ---------DPTNLYISNLPLSMDEQE 150
+ + QA++ ++ EQ NLYI NL ++D+++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 151 LEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPS 210
L PFG + S +++ + G S+G GF S E+ +T NG+ + S
Sbjct: 310 LRKEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIV--------GS 360
Query: 211 DPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPTTALQNGFYPAPYNITP 270
PL A +R+ + K + R A M + P A+ N F PA
Sbjct: 361 KPLYVALA-----QRKEERKAHLTNQYMQRVAGMRAL-----PANAILNQFQPAAGGYFV 410
Query: 271 NRMLAQSALSPYLSSPVSSYQRVTQTSPLQVPNPSW 306
+ PY + + R PNP W
Sbjct: 411 PAVPQAQGRPPYYTPNQLAQMR---------PNPRW 437
Score = 77.4 bits (189), Expect = 2e-14
Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 17/159 (10%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
N++I+ L ++ L +G I+S K + D+ N KGY FV F++ AA KA+
Sbjct: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
Query: 117 L--------KASGVQAQMAKQQE-------QDPTNLYISNLPLSMDEQELEGMLKPFGQV 161
+ K + + K++E ++ TN+YI N +D++ L+ + FG+
Sbjct: 158 MNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKT 217
Query: 162 ISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYI 200
+S +++RD +G S+G GF E E + NGK I
Sbjct: 218 LSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEI 256
Score = 68.2 bits (165), Expect = 1e-11
Identities = 39/150 (26%), Positives = 74/150 (49%), Gaps = 10/150 (6%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
+LY+ L T+ L + P G ++S + D T + GY +V+F P+ A++A+
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 117 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRIL 167
+ ++ + + ++DP+ N++I NL S+D + L FG ++S +++
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 168 RDTSGTSRGVGFARMESTEKCEAIITHFNG 197
D +G S+G F E+ E + I NG
Sbjct: 132 CDENG-SKGYAFVHFETQEAADKAIEKMNG 160
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 79.3 bits (194), Expect = 6e-15
Identities = 70/276 (25%), Positives = 110/276 (39%), Gaps = 54/276 (19%)
Query: 56 TNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVT 115
TN+YI+ D+ L +L +GK +S K + D K KG+GFV ++ A KAV
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVE 249
Query: 116 ALKASGV----------------QAQMAKQQEQ---------DPTNLYISNLPLSMDEQE 150
+ + QA++ ++ EQ NLYI NL ++D+++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 151 LEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPS 210
L PFG + S +++ + G S+G GF S E+ +T NG+ + S
Sbjct: 310 LRKEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIV--------GS 360
Query: 211 DPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPTTALQNGFYPAPYNITP 270
PL A +R+ + K + R A M + P A+ N F PA
Sbjct: 361 KPLYVALA-----QRKEERKAHLTNQYMQRVAGMRAL-----PANAILNQFQPAAGGYFV 410
Query: 271 NRMLAQSALSPYLSSPVSSYQRVTQTSPLQVPNPSW 306
+ PY + + R PNP W
Sbjct: 411 PAVPQAQGRPPYYTPNQLAQMR---------PNPRW 437
Score = 77.4 bits (189), Expect = 2e-14
Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 17/159 (10%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
N++I+ L ++ L +G I+S K + D+ N KGY FV F++ AA KA+
Sbjct: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
Query: 117 L--------KASGVQAQMAKQQE-------QDPTNLYISNLPLSMDEQELEGMLKPFGQV 161
+ K + + K++E ++ TN+YI N +D++ L+ + FG+
Sbjct: 158 MNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKT 217
Query: 162 ISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYI 200
+S +++RD +G S+G GF E E + NGK I
Sbjct: 218 LSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEI 256
Score = 68.2 bits (165), Expect = 1e-11
Identities = 39/150 (26%), Positives = 74/150 (49%), Gaps = 10/150 (6%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
+LY+ L T+ L + P G ++S + D T + GY +V+F P+ A++A+
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 117 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRIL 167
+ ++ + + ++DP+ N++I NL S+D + L FG ++S +++
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 168 RDTSGTSRGVGFARMESTEKCEAIITHFNG 197
D +G S+G F E+ E + I NG
Sbjct: 132 CDENG-SKGYAFVHFETQEAADKAIEKMNG 160
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 79.3 bits (194), Expect = 6e-15
Identities = 70/276 (25%), Positives = 110/276 (39%), Gaps = 54/276 (19%)
Query: 56 TNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVT 115
TN+YI+ D+ L +L +GK +S K + D K KG+GFV ++ A KAV
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVE 249
Query: 116 ALKASGV----------------QAQMAKQQEQ---------DPTNLYISNLPLSMDEQE 150
+ + QA++ ++ EQ NLYI NL ++D+++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 151 LEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPS 210
L PFG + S +++ + G S+G GF S E+ +T NG+ + S
Sbjct: 310 LRKEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIV--------GS 360
Query: 211 DPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPTTALQNGFYPAPYNITP 270
PL A +R+ + K + R A M + P A+ N F PA
Sbjct: 361 KPLYVALA-----QRKEERKAHLTNQYMQRVAGMRAL-----PANAILNQFQPAAGGYFV 410
Query: 271 NRMLAQSALSPYLSSPVSSYQRVTQTSPLQVPNPSW 306
+ PY + + R PNP W
Sbjct: 411 PAVPQAQGRPPYYTPNQLAQMR---------PNPRW 437
Score = 77.4 bits (189), Expect = 2e-14
Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 17/159 (10%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
N++I+ L ++ L +G I+S K + D+ N KGY FV F++ AA KA+
Sbjct: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
Query: 117 L--------KASGVQAQMAKQQE-------QDPTNLYISNLPLSMDEQELEGMLKPFGQV 161
+ K + + K++E ++ TN+YI N +D++ L+ + FG+
Sbjct: 158 MNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKT 217
Query: 162 ISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYI 200
+S +++RD +G S+G GF E E + NGK I
Sbjct: 218 LSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEI 256
Score = 68.2 bits (165), Expect = 1e-11
Identities = 39/150 (26%), Positives = 74/150 (49%), Gaps = 10/150 (6%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
+LY+ L T+ L + P G ++S + D T + GY +V+F P+ A++A+
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 117 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRIL 167
+ ++ + + ++DP+ N++I NL S+D + L FG ++S +++
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 168 RDTSGTSRGVGFARMESTEKCEAIITHFNG 197
D +G S+G F E+ E + I NG
Sbjct: 132 CDENG-SKGYAFVHFETQEAADKAIEKMNG 160
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 77.4 bits (189), Expect = 2e-14
Identities = 49/182 (26%), Positives = 88/182 (48%), Gaps = 21/182 (11%)
Query: 38 NSTPNSSSGSNGNDQLSKT---NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTN 94
N P S +D+L K+ N++I+ L ++ L L +G I+S K + D N
Sbjct: 85 NGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--N 142
Query: 95 KCKGYGFVDFDSPSAAQKAVTALKASGVQ----------------AQMAKQQEQDPTNLY 138
KGY +V FDS +AA +A+ + + A++ + TN++
Sbjct: 143 GSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVF 202
Query: 139 ISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGK 198
+ N+ +D+++L+ + +G S +++RD SG S+G GF R E+ E + + +GK
Sbjct: 203 VKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGK 262
Query: 199 YI 200
I
Sbjct: 263 SI 264
Score = 67.0 bits (162), Expect = 3e-11
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 10/152 (6%)
Query: 55 KTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAV 114
K LY+ L P T+ L K +P G + T+ D T GYG+V+F P+ A+ A+
Sbjct: 17 KAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWAL 76
Query: 115 TALKASGVQAQMAKQQEQDPT---------NLYISNLPLSMDEQELEGMLKPFGQVISTR 165
+ + + + P N++I NL S+D + L + FG ++S +
Sbjct: 77 NTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCK 136
Query: 166 ILRDTSGTSRGVGFARMESTEKCEAIITHFNG 197
++ D +G S+G + +S I H NG
Sbjct: 137 VVCDDNG-SKGYAYVHFDSLAAANRAIWHMNG 167
Score = 63.2 bits (152), Expect = 4e-10
Identities = 42/179 (23%), Positives = 81/179 (45%), Gaps = 27/179 (15%)
Query: 51 DQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAA 110
D+ + TN++++ + D+ L +L YG S K I D + K KG+GFV +++ AA
Sbjct: 194 DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAA 252
Query: 111 QKAVTALKASGVQAQM------------------------AKQQEQDP-TNLYISNLPLS 145
QKAV L + ++ K++ + P +YI NL +
Sbjct: 253 QKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDET 312
Query: 146 MDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPP 204
+++++L+ FG + +++ + G +G G S E+ + NG+ + + P
Sbjct: 313 INDEKLKEEFSSFGSISRAKVMMEV-GQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKP 370
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 76.3 bits (186), Expect = 5e-14
Identities = 42/158 (26%), Positives = 77/158 (48%), Gaps = 19/158 (12%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
N++++ L ++ L +G I+S + D+ N KGYGFV F++ AA++A+
Sbjct: 100 NIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDE--NGSKGYGFVHFETHEAAERAIKK 157
Query: 117 LKASGV----------------QAQMAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQ 160
+ + +A++ + ++ P N+YI N MD++ L+ + FG
Sbjct: 158 MNGMLLNGRKVFVGQFKSRKEREAELGARAKEFP-NVYIKNFGEDMDDERLKDLFGKFGP 216
Query: 161 VISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGK 198
+S +++ D SG S+G GF E E + + NGK
Sbjct: 217 ALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGK 254
Score = 75.5 bits (184), Expect = 8e-14
Identities = 49/173 (28%), Positives = 76/173 (43%), Gaps = 27/173 (15%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAV-- 114
N+YI+ D+ L L +G +S K + D++ K KG+GFV F+ AQKAV
Sbjct: 192 NVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDES-GKSKGFGFVSFERHEDAQKAVDE 250
Query: 115 -----------------------TALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQEL 151
T LK + Q + + NLY+ NL +D++ L
Sbjct: 251 MNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERL 310
Query: 152 EGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPP 204
PFG + S +++ + G S+G GF S E+ +T NG+ + T P
Sbjct: 311 RKAFSPFGTITSAKVMME-GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKP 362
Score = 64.3 bits (155), Expect = 2e-10
Identities = 39/150 (26%), Positives = 72/150 (48%), Gaps = 10/150 (6%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
+LY+ L P T+ L + P G I+S + D T+ Y +V+F A+ A+
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDT 71
Query: 117 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRIL 167
+ ++ + + ++DP+ N+++ NL S++ + L + FG ++S ++
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVV 131
Query: 168 RDTSGTSRGVGFARMESTEKCEAIITHFNG 197
D +G S+G GF E+ E E I NG
Sbjct: 132 CDENG-SKGYGFVHFETHEAAERAIKKMNG 160
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 74.7 bits (182), Expect = 1e-13
Identities = 42/159 (26%), Positives = 79/159 (49%), Gaps = 17/159 (10%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
N++I+ L ++ L + +GKI+S+K + D +K GY FV F + SAA +A+
Sbjct: 99 NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSK--GYAFVHFQNQSAADRAIEE 156
Query: 117 LKASGVQAQMA---------------KQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQV 161
+ ++ + + + TN+YI N MD++ L+ + +G+
Sbjct: 157 MNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKT 216
Query: 162 ISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYI 200
+S +++ D+SG S+G GF +S E + + NG+ I
Sbjct: 217 LSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDI 255
Score = 73.9 bits (180), Expect = 2e-13
Identities = 49/174 (28%), Positives = 80/174 (45%), Gaps = 27/174 (15%)
Query: 56 TNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVT 115
TN+YI+ D+ L + YGK +S K + D ++ K KG+GFV FDS AA+KAV
Sbjct: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVE 248
Query: 116 ALKASGV----------------QAQMAKQQEQ---------DPTNLYISNLPLSMDEQE 150
+ + QA++ + EQ LYI NL ++D+++
Sbjct: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
Query: 151 LEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPP 204
L FG + +++++ G S+G G S E +T NG+ + + P
Sbjct: 309 LRNEFSSFGSISRVKVMQE-EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKP 361
Score = 62.8 bits (151), Expect = 5e-10
Identities = 38/154 (24%), Positives = 74/154 (48%), Gaps = 10/154 (6%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
+LY+ L T+ L + G ++S + D+ T + GY +V+F + AQKA+
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 117 -----LKASGVQAQMAKQ----QEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRIL 167
+K ++ +++ + N++I NL S+D + L FG+++S++++
Sbjct: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
Query: 168 RDTSGTSRGVGFARMESTEKCEAIITHFNGKYIK 201
D G S+G F ++ + I NGK +K
Sbjct: 131 SDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLK 163
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 71.2 bits (173), Expect = 2e-12
Identities = 41/153 (26%), Positives = 75/153 (49%), Gaps = 10/153 (6%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
+LY+ L P T+ L + P G I+S + DK T + GY +V++ P A++A+
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 117 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRIL 167
L ++ + + ++DP+ N++I NL ++D + L + FG ++S ++
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122
Query: 168 RDTSGTSRGVGFARMESTEKCEAIITHFNGKYI 200
D G +G GF + E E I NG ++
Sbjct: 123 CDEKG-PKGYGFVHFQKQESAERAIDVMNGMFL 154
>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
sapiens]
Length = 485
Score = 71.2 bits (173), Expect = 2e-12
Identities = 92/390 (23%), Positives = 153/390 (39%), Gaps = 60/390 (15%)
Query: 29 QQMAPPSPS---NSTPNSSSGS-NGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVS 84
QQ+ P PS +S P G +G L L++ + ++DL L + +G+I
Sbjct: 14 QQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYE 73
Query: 85 TKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDPTN-------- 136
+ D T KG F+ + + +A KA TAL MA+ + P +
Sbjct: 74 LTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRD 133
Query: 137 --LYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITH 194
L++ L E+++ + +PFG + +LR G+S+G F + S + +A I
Sbjct: 134 RKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHA 193
Query: 195 FNGKYIKTPPGVPAPSDPLLCKFADGGPKK--RQNQGKFVQNGRAWPRNADMGVMALTYD 252
+G +T PG S L+ KFAD ++ R+ Q Q G P + L +
Sbjct: 194 LHGS--QTMPGA---SSSLVVKFADTDKERTLRRMQQMVGQLGILTPS------LTLPFS 242
Query: 253 PTTALQNGFYPAPYNITPNRMLAQSALSPYLSSPVSSYQRVTQTSPLQVP-----NPSWM 307
P +A + + S LSP ++ Q++ S +P S +
Sbjct: 243 PYSAYAQALMQQQTTVLST---SGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGL 299
Query: 308 HHHSYLMQPSGSVLTPGMDHPISLQPASMMGPLTQQLGHLSLSSTGTYMPTAAAMQGAYI 367
H L G+ PG+ PI+ G + GH A++ Y
Sbjct: 300 HSPPLL----GTTAVPGLVAPIT---NGFAGVVPFPGGH-------------PALETVYA 339
Query: 368 SQYTPVPSSSVSVEES-----SGQQNQVAV 392
+ P P+ S +V E+ SG Q A+
Sbjct: 340 NGLVPYPAQSPTVAETLHPAFSGVQQYTAM 369
Score = 59.3 bits (142), Expect = 6e-09
Identities = 28/78 (35%), Positives = 47/78 (60%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
NL+I L D +L ++ P+G I+S+K +D+ TN+ K +GFV FD+P++AQ A+ A
Sbjct: 401 NLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQA 460
Query: 117 LKASGVQAQMAKQQEQDP 134
+ + + K Q + P
Sbjct: 461 MNGFQIGMKRLKVQLKRP 478
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 8/108 (7%)
Query: 113 AVTALKASGVQAQMAKQQEQ----DPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILR 168
A+T + S Q QQ+Q + NL+I +LP + EL M PFG +IS+++
Sbjct: 374 AITPIAHSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFM 433
Query: 169 D-TSGTSRGVGFARMESTEKCEAIITHFNGKYI---KTPPGVPAPSDP 212
D + S+ GF ++ +A I NG I + + P DP
Sbjct: 434 DRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDP 481
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 71.2 bits (173), Expect = 2e-12
Identities = 41/153 (26%), Positives = 75/153 (49%), Gaps = 10/153 (6%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
+LY+ L P T+ L + P G I+S + DK T + GY +V++ P A++A+
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 117 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRIL 167
L ++ + + ++DP+ N++I NL ++D + L + FG ++S ++
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122
Query: 168 RDTSGTSRGVGFARMESTEKCEAIITHFNGKYI 200
D G +G GF + E E I NG ++
Sbjct: 123 CDEKG-PKGYGFVHFQKQESAERAIDVMNGMFL 154
>gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]
Length = 465
Score = 69.7 bits (169), Expect = 4e-12
Identities = 84/370 (22%), Positives = 146/370 (39%), Gaps = 44/370 (11%)
Query: 58 LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117
L++ + ++DL + + +G+I I DK T KG F+ + + +A KA +AL
Sbjct: 9 LFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSAL 68
Query: 118 KASGVQAQMAKQQEQDPTN---------LYISNLPLSMDEQELEGMLKPFGQVISTRILR 168
M + + P + L++ L ++++ M +PFG + +LR
Sbjct: 69 HEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLR 128
Query: 169 DTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKK--RQ 226
GTS+G F + ++ + +A I + +T PG S L+ KFAD ++ R+
Sbjct: 129 GPDGTSKGCAFVKFQTHAEAQAAINTLHSS--RTLPGA---SSSLVVKFADTEKERGLRR 183
Query: 227 NQGKFVQNGRAWPRNADMGVMALTYDPTTALQNGFYPAPYNITPNRMLAQSAL------- 279
Q Q G P G + Y Q A ++ + M +A+
Sbjct: 184 MQQVATQLGMFSPIALQFGAYS-AYTQALMQQQAALVAAHSAYLSPMATMAAVQMQHMAA 242
Query: 280 --------SPYL-SSPVSSYQRVTQTSPLQVPNPSWMHHHSYLM-----QPSGSVLTPGM 325
+P SS S+ + T +P ++ +S + QP+ L P
Sbjct: 243 INANGLIATPITPSSGTSTPPAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDALYPNG 302
Query: 326 DHPISLQ-PASMMGPLTQQ---LGHLSLSSTGTYMPTAAA--MQGAYISQYTPVPSSSVS 379
HP Q PA+ + PL Q + H + + Y A A A ++Q P P
Sbjct: 303 VHPYPAQSPAAPVDPLQQAYAGMQHYTAAYPAAYSLVAPAFPQPPALVAQQPPPPPQQQQ 362
Query: 380 VEESSGQQNQ 389
++ QQ Q
Sbjct: 363 QQQQQQQQQQ 372
Score = 61.6 bits (148), Expect = 1e-09
Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 2/111 (1%)
Query: 26 SLAQQMAPPSPSNSTPNSSSGSNGNDQLSKT--NLYIRGLQPGTTDQDLVKLCQPYGKIV 83
+L Q PP P + N++I L TD +++++ P+G ++
Sbjct: 348 ALVAQQPPPPPQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVI 407
Query: 84 STKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQEQDP 134
S K +D+ TN+ K +GFV FD+P++AQ A+ A+ + + K Q + P
Sbjct: 408 SAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRP 458
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Query: 123 QAQMAKQQEQ----DPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGV 177
Q Q +QQ+Q D N++I +LP + E+ M PFG VIS ++ D + S+
Sbjct: 364 QQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCF 423
Query: 178 GFARMESTEKCEAIITHFNG 197
GF ++ +A I NG
Sbjct: 424 GFVSFDNPASAQAAIQAMNG 443
Score = 38.1 bits (87), Expect = 0.014
Identities = 68/310 (21%), Positives = 109/310 (35%), Gaps = 43/310 (13%)
Query: 43 SSSGSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFV 102
+ S S G D+ L++ L TD+D+ K+ +P+G I +L KG FV
Sbjct: 86 ADSESRGEDR----KLFVGMLGKQQTDEDVRKMFEPFGTI-DECTVLRGPDGTSKGCAFV 140
Query: 103 DFDSPSAAQKAVTALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVI 162
F + + AQ A+ L +S + S+L + + E E L+ QV
Sbjct: 141 KFQTHAEAQAAINTLHSSRTLPGAS------------SSLVVKFADTEKERGLRRMQQVA 188
Query: 163 STRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGP 222
+ + G A ++ + +A + + Y L A
Sbjct: 189 TQLGMFSPIALQFGAYSAYTQALMQQQAALVAAHSAY--------------LSPMATMAA 234
Query: 223 KKRQNQGKFVQNGR-AWPRNADMGVM---ALTYDPTTALQ-----NGFYPAPYNITPNRM 273
+ Q+ NG A P G A+ P +A+ NG+ P P P
Sbjct: 235 VQMQHMAAINANGLIATPITPSSGTSTPPAIAATPVSAIPAALGVNGYSPVP--TQPTGQ 292
Query: 274 LAQSALSPYLSSPVSSYQRVTQTSPLQVPNPSWMHHHSYLMQPSGSVLTPGMDHPISLQP 333
A AL P P + PLQ + M H++ + S++ P P +L
Sbjct: 293 PAPDALYPNGVHPYPAQSPAAPVDPLQQAY-AGMQHYTAAYPAAYSLVAPAFPQPPALVA 351
Query: 334 ASMMGPLTQQ 343
P QQ
Sbjct: 352 QQPPPPPQQQ 361
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 64.3 bits (155), Expect = 2e-10
Identities = 46/157 (29%), Positives = 76/157 (48%), Gaps = 10/157 (6%)
Query: 58 LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQ---KAV 114
+Y+ GL ++ L +L G +V+T D+ T + +GYGFV+F S A K +
Sbjct: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
Query: 115 TALKASGVQAQMAKQQEQDP-----TNLYISNLPLSMDEQELEGMLKPFGQVIST-RILR 168
+K G ++ K + N++I NL +DE+ L FG ++ T +I+R
Sbjct: 75 NMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMR 134
Query: 169 D-TSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPP 204
D +G S+G F S + +A I NG+Y+ P
Sbjct: 135 DPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRP 171
>gi|134152680 CUG triplet repeat, RNA binding protein 2 isoform 2
[Homo sapiens]
Length = 521
Score = 63.5 bits (153), Expect = 3e-10
Identities = 55/222 (24%), Positives = 95/222 (42%), Gaps = 21/222 (9%)
Query: 23 PYVSLAQQMAPPSPSNSTPNSSSGS-NGNDQLSKT--NLYIRGLQPGTTDQDLVKLCQPY 79
P + + ++ P N T N +G+ + +DQ +++ + ++++L +L +PY
Sbjct: 11 PDMMVEGRLLVPDRINGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPY 70
Query: 80 GKIVSTKAILDKTTN--KCKGYGFVDFDSPSAAQKAVTALK----ASGVQ-------AQM 126
G + + D++ N + KG FV F + AA +A AL G+ A
Sbjct: 71 GAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADS 130
Query: 127 AKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTE 186
K + L+I + +E ++ M PFGQ+ RILR G SRG F +
Sbjct: 131 EKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRA 190
Query: 187 KCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQ 228
+ I K + + S P++ KFAD K Q +
Sbjct: 191 MAQNAI-----KAMHQSQTMEGCSSPIVVKFADTQKDKEQRR 227
Score = 58.9 bits (141), Expect = 8e-09
Identities = 27/74 (36%), Positives = 44/74 (59%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
NL+I L DQD++++ P+G ++S K +DK TN K +GFV +D+P +AQ A+ A
Sbjct: 437 NLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQA 496
Query: 117 LKASGVQAQMAKQQ 130
+ + + K Q
Sbjct: 497 MNGFQIGMKRLKVQ 510
Score = 45.4 bits (106), Expect = 9e-05
Identities = 47/171 (27%), Positives = 76/171 (44%), Gaps = 12/171 (7%)
Query: 39 STPNSSSGSNGNDQLSKTNLY-IRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKT--TNK 95
STPNS++G+ N S L + G G + + + + Q + + L T TN
Sbjct: 329 STPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAVAQMLSGMAALNGGLGATGLTNG 388
Query: 96 CKGYGFVDFDSPSAAQK-AVTALKASGVQAQMAKQ-----QEQDP--TNLYISNLPLSMD 147
G + S Q+ A AL Q+ + +Q Q++ P NL+I +LP
Sbjct: 389 TAGTMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGPEGANLFIYHLPQEFG 448
Query: 148 EQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHFNG 197
+Q++ M PFG VIS ++ D + S+ GF ++ +A I NG
Sbjct: 449 DQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNG 499
>gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3
[Homo sapiens]
Length = 508
Score = 63.2 bits (152), Expect = 4e-10
Identities = 54/208 (25%), Positives = 90/208 (43%), Gaps = 21/208 (10%)
Query: 37 SNSTPNSSSGS-NGNDQLSKT--NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTT 93
SN T N +G+ + +DQ +++ + ++++L +L +PYG + + D++
Sbjct: 18 SNGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQ 77
Query: 94 N--KCKGYGFVDFDSPSAAQKAVTALK----ASGVQ-------AQMAKQQEQDPTNLYIS 140
N + KG FV F + AA +A AL G+ A K + L+I
Sbjct: 78 NPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIG 137
Query: 141 NLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYI 200
+ +E ++ M PFGQ+ RILR G SRG F + + I K +
Sbjct: 138 MVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAI-----KAM 192
Query: 201 KTPPGVPAPSDPLLCKFADGGPKKRQNQ 228
+ S P++ KFAD K Q +
Sbjct: 193 HQSQTMEGCSSPIVVKFADTQKDKEQRR 220
Score = 58.9 bits (141), Expect = 8e-09
Identities = 27/74 (36%), Positives = 44/74 (59%)
Query: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
NL+I L DQD++++ P+G ++S K +DK TN K +GFV +D+P +AQ A+ A
Sbjct: 424 NLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQA 483
Query: 117 LKASGVQAQMAKQQ 130
+ + + K Q
Sbjct: 484 MNGFQIGMKRLKVQ 497
Score = 43.1 bits (100), Expect = 4e-04
Identities = 47/173 (27%), Positives = 69/173 (39%), Gaps = 22/173 (12%)
Query: 39 STPNSSSGSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPY----------GKIVSTKAI 88
STPNS++G+ N S L +GL T + + G T
Sbjct: 322 STPNSTAGAAMNSLTSLGTL--QGLAGATVGLNNINALAGMAALNGGLGATGLTNGTAGT 379
Query: 89 LDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAK-QQEQDP--TNLYISNLPLS 145
+D T G AA T S +Q Q A Q++ P NL+I +LP
Sbjct: 380 MDALTQAYSGI------QQYAAAALPTLYSQSLLQQQSAAGSQKEGPEGANLFIYHLPQE 433
Query: 146 MDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHFNG 197
+Q++ M PFG VIS ++ D + S+ GF ++ +A I NG
Sbjct: 434 FGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNG 486
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.127 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,209,389
Number of Sequences: 37866
Number of extensions: 866509
Number of successful extensions: 3200
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 198
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 2462
Number of HSP's gapped (non-prelim): 612
length of query: 407
length of database: 18,247,518
effective HSP length: 105
effective length of query: 302
effective length of database: 14,271,588
effective search space: 4310019576
effective search space used: 4310019576
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.