Search of human proteins with 4506201

Search of human proteins with 4506201

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506201 proteasome beta 5 subunit isoform 1 [Homo sapiens]
         (263 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506201 proteasome beta 5 subunit isoform 1 [Homo sapiens]         532   e-151
gi|222144262 proteasome beta 5 subunit isoform 3 [Homo sapiens]       340   1e-93
gi|195539356 proteasome beta 5 subunit isoform 2 [Homo sapiens]       330   1e-90
gi|73747875 proteasome beta 8 subunit isoform E2 proprotein [Hom...   308   4e-84
gi|4758970 proteasome beta 8 subunit isoform E1 proprotein [Homo...   308   4e-84
gi|153791216 proteasome beta 11 subunit [Homo sapiens]                238   5e-63
gi|23110925 proteasome beta 6 subunit [Homo sapiens]                  102   3e-22
gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo...    90   2e-18
gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo ...    90   2e-18
gi|4506203 proteasome beta 7 subunit proprotein [Homo sapiens]         87   2e-17
gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens]        80   1e-15
gi|4506193 proteasome beta 1 subunit [Homo sapiens]                    56   4e-08
gi|22538467 proteasome beta 4 subunit [Homo sapiens]                   52   5e-07
gi|22538465 proteasome beta 3 subunit [Homo sapiens]                   52   7e-07
gi|4506181 proteasome subunit alpha type 2 [Homo sapiens]              49   4e-06
gi|23110942 proteasome alpha 5 subunit [Homo sapiens]                  47   2e-05
gi|4506189 proteasome alpha 7 subunit [Homo sapiens]                   43   3e-04
gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens]        37   0.023
gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens]         35   0.087
gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens]        35   0.087
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]         34   0.11 
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]         34   0.11 
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                29   3.7  
gi|169217837 PREDICTED: similar to hCG1773549 [Homo sapiens]           29   4.8  
gi|34577122 nuclear factor kappa-B, subunit 1 [Homo sapiens]           28   6.2  

>gi|4506201 proteasome beta 5 subunit isoform 1 [Homo sapiens]
          Length = 263

 Score =  532 bits (1370), Expect = e-151
 Identities = 263/263 (100%), Positives = 263/263 (100%)

Query: 1   MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT 60
           MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT
Sbjct: 1   MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT 60

Query: 61  TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR 120
           TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR
Sbjct: 61  TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR 120

Query: 121 QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI 180
           QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI
Sbjct: 121 QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI 180

Query: 181 SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE 240
           SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE
Sbjct: 181 SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE 240

Query: 241 DGWIRVSSDNVADLHEKYSGSTP 263
           DGWIRVSSDNVADLHEKYSGSTP
Sbjct: 241 DGWIRVSSDNVADLHEKYSGSTP 263


>gi|222144262 proteasome beta 5 subunit isoform 3 [Homo sapiens]
          Length = 203

 Score =  340 bits (871), Expect = 1e-93
 Identities = 168/168 (100%), Positives = 168/168 (100%)

Query: 1   MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT 60
           MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT
Sbjct: 1   MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT 60

Query: 61  TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR 120
           TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR
Sbjct: 61  TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR 120

Query: 121 QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGP 168
           QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGP
Sbjct: 121 QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGP 168


>gi|195539356 proteasome beta 5 subunit isoform 2 [Homo sapiens]
          Length = 160

 Score =  330 bits (845), Expect = 1e-90
 Identities = 160/160 (100%), Positives = 160/160 (100%)

Query: 104 MAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGW 163
           MAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGW
Sbjct: 1   MAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGW 60

Query: 164 DKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQAT 223
           DKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQAT
Sbjct: 61  DKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQAT 120

Query: 224 YRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP 263
           YRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
Sbjct: 121 YRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP 160


>gi|73747875 proteasome beta 8 subunit isoform E2 proprotein [Homo
           sapiens]
          Length = 276

 Score =  308 bits (788), Expect = 4e-84
 Identities = 144/205 (70%), Positives = 174/205 (84%)

Query: 54  IEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSF 113
           IEM HGTTTLAFKF+HGVI A DSRA+AG+YI++  V KVIEINPYLLGTM+G AADC +
Sbjct: 67  IEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQY 126

Query: 114 WERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYV 173
           WERLLA++CR+Y LRN ERISV+AASKLL+NM+ QY+GMGLSMG+MICGWDK+GPGLYYV
Sbjct: 127 WERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYV 186

Query: 174 DSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAV 233
           D  G R+SG  FS GSG+ YAYGVMD GY  +L  E+AYDL RRAI  AT+RD+YSGG V
Sbjct: 187 DEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVV 246

Query: 234 NLYHVREDGWIRVSSDNVADLHEKY 258
           N+YH++EDGW++V S +V+DL  +Y
Sbjct: 247 NMYHMKEDGWVKVESTDVSDLLHQY 271


>gi|4758970 proteasome beta 8 subunit isoform E1 proprotein [Homo
           sapiens]
          Length = 272

 Score =  308 bits (788), Expect = 4e-84
 Identities = 144/205 (70%), Positives = 174/205 (84%)

Query: 54  IEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSF 113
           IEM HGTTTLAFKF+HGVI A DSRA+AG+YI++  V KVIEINPYLLGTM+G AADC +
Sbjct: 63  IEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQY 122

Query: 114 WERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYV 173
           WERLLA++CR+Y LRN ERISV+AASKLL+NM+ QY+GMGLSMG+MICGWDK+GPGLYYV
Sbjct: 123 WERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYV 182

Query: 174 DSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAV 233
           D  G R+SG  FS GSG+ YAYGVMD GY  +L  E+AYDL RRAI  AT+RD+YSGG V
Sbjct: 183 DEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVV 242

Query: 234 NLYHVREDGWIRVSSDNVADLHEKY 258
           N+YH++EDGW++V S +V+DL  +Y
Sbjct: 243 NMYHMKEDGWVKVESTDVSDLLHQY 267


>gi|153791216 proteasome beta 11 subunit [Homo sapiens]
          Length = 300

 Score =  238 bits (606), Expect = 5e-63
 Identities = 117/222 (52%), Positives = 158/222 (71%), Gaps = 9/222 (4%)

Query: 43  APGWGVPE--EP-------GIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKV 93
           A GW VP   +P       G  + HGTTTLAF+FRHGVI AAD+R++ G+Y+A     KV
Sbjct: 24  AGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKV 83

Query: 94  IEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMG 153
           I ++ +LLGT +G +ADC+ W R+L R+ R+ ELR  +  SVA+A+KLL+ M+ QY+G+ 
Sbjct: 84  IPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLD 143

Query: 154 LSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYD 213
           L + T +CGWD+ GP L+YV S+G R+ G  FSVGSGS YAYGV+DRGY YD+  ++AY 
Sbjct: 144 LCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYA 203

Query: 214 LARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLH 255
           LAR A+  AT+RDAYSGG+V+L+HVRE GW  VS  +   L+
Sbjct: 204 LARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSDACVLY 245


>gi|23110925 proteasome beta 6 subunit [Homo sapiens]
          Length = 239

 Score =  102 bits (255), Expect = 3e-22
 Identities = 66/205 (32%), Positives = 97/205 (47%), Gaps = 6/205 (2%)

Query: 43  APGWG----VPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINP 98
           AP WG     P+    E+  GTT +A +F  GV++ ADSR T G+YIA++   K+  I+ 
Sbjct: 14  APAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHD 73

Query: 99  YLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGT 158
            +    +G AAD       +  Q   + +   E   V  A+ L   M Y+Y+   L  G 
Sbjct: 74  RIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYR-EDLMAGI 132

Query: 159 MICGWDKRGPGLYYVDSEGNRISGATFSV-GSGSVYAYGVMDRGYSYDLEVEQAYDLARR 217
           +I GWD +  G  Y    G  +   +F++ GSGS Y YG +D  Y   +  E+       
Sbjct: 133 IIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTAN 192

Query: 218 AIYQATYRDAYSGGAVNLYHVREDG 242
           A+  A  RD  SGG + L  + E G
Sbjct: 193 ALALAMERDGSSGGVIRLAAIAESG 217


>gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo
           sapiens]
          Length = 209

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 3/189 (1%)

Query: 55  EMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFW 114
           E+  GTT +A +F  GV++ +DSR +AG  + ++   K+  ++  +   ++G AAD    
Sbjct: 6   EVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAV 65

Query: 115 ERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVD 174
             + A Q  ++ +  +E   V AA+ ++ N+ Y+Y+   LS   M+ GWD+R  G  Y  
Sbjct: 66  ADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVY-G 123

Query: 175 SEGNRISGATFSV-GSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAV 233
           + G  ++   F++ GSGS + YG +D  Y   +  E+       AI  A  RD  SGG +
Sbjct: 124 TLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVI 183

Query: 234 NLYHVREDG 242
            L  +   G
Sbjct: 184 YLVTITAAG 192


>gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo
           sapiens]
          Length = 219

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 3/189 (1%)

Query: 55  EMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFW 114
           E+  GTT +A +F  GV++ +DSR +AG  + ++   K+  ++  +   ++G AAD    
Sbjct: 16  EVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAV 75

Query: 115 ERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVD 174
             + A Q  ++ +  +E   V AA+ ++ N+ Y+Y+   LS   M+ GWD+R  G  Y  
Sbjct: 76  ADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVY-G 133

Query: 175 SEGNRISGATFSV-GSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAV 233
           + G  ++   F++ GSGS + YG +D  Y   +  E+       AI  A  RD  SGG +
Sbjct: 134 TLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVI 193

Query: 234 NLYHVREDG 242
            L  +   G
Sbjct: 194 YLVTITAAG 202


>gi|4506203 proteasome beta 7 subunit proprotein [Homo sapiens]
          Length = 277

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 51/177 (28%), Positives = 90/177 (50%), Gaps = 1/177 (0%)

Query: 59  GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118
           GTT     ++ G+++ AD+RAT G  +A +   K+  I+P +    AG AAD     +L+
Sbjct: 43  GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLI 102

Query: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGN 178
           +    ++ L       V  A+++L  M+++Y+G  +    ++ G D  GP LY +   G+
Sbjct: 103 SSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGY-IGAALVLGGVDVTGPHLYSIYPHGS 161

Query: 179 RISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNL 235
                  ++GSGS+ A  V +  +  D+E E+A +L   AI    + D  SG  ++L
Sbjct: 162 TDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDL 218


>gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens]
          Length = 273

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 57/196 (29%), Positives = 99/196 (50%), Gaps = 7/196 (3%)

Query: 52  PGIEMLH----GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGG 107
           PG+++ H    GTT     F+ GVI+ AD+RAT  + +A ++ +K+  I P +    AG 
Sbjct: 28  PGLKVPHARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGV 87

Query: 108 AADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKG-MGLSMGTMICGWDKR 166
           AAD     R++A +  ++ L       VA  +++L   +++Y+G +G S+  ++ G D  
Sbjct: 88  AADAEMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASL--IVGGVDLT 145

Query: 167 GPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRD 226
           GP LY V   G+       ++GSG   A  V++  +  ++ +E A  L   A+      D
Sbjct: 146 GPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGD 205

Query: 227 AYSGGAVNLYHVREDG 242
             SGG V+   + + G
Sbjct: 206 LGSGGNVDACVITKTG 221


>gi|4506193 proteasome beta 1 subunit [Homo sapiens]
          Length = 241

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 43/197 (21%), Positives = 89/197 (45%), Gaps = 10/197 (5%)

Query: 56  MLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWE 115
           + +G T LA       IVA+D+R + G  I ++   K  ++    +   +G   DC    
Sbjct: 34  VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 93

Query: 116 RLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPG-LYYVD 174
           +++  + ++Y+  N + ++  A + +L+ ++Y  +     +  +I G D+ G G +Y  D
Sbjct: 94  KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 153

Query: 175 SEGNRISGATFSVGSGSVYAYGVMDRGYSY---------DLEVEQAYDLARRAIYQATYR 225
             G+    +  + GS S     ++D    +          L +++A  L +     A  R
Sbjct: 154 PVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAER 213

Query: 226 DAYSGGAVNLYHVREDG 242
           D Y+G A+ +  V ++G
Sbjct: 214 DVYTGDALRICIVTKEG 230


>gi|22538467 proteasome beta 4 subunit [Homo sapiens]
          Length = 264

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 49/192 (25%), Positives = 80/192 (41%), Gaps = 5/192 (2%)

Query: 56  MLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWE 115
           M+ GT+ L  KF  GV++AAD   + G+    + + +++ +N   +   +G  AD  + +
Sbjct: 50  MVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLK 109

Query: 116 RLLARQCRIYE-LRNKERISVAAASKLLANMVYQYKG-MGLSMGTMICGWDKRGPG-LYY 172
           ++L +     E L +    S  A    L   +Y  +  M     TM+ G    G   L Y
Sbjct: 110 QVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGY 169

Query: 173 VDSEGNRISGATFSVGSGSVYAYGVMDRGYSYD--LEVEQAYDLARRAIYQATYRDAYSG 230
           VD  G      + + G G+  A  ++         L   +A DL  R +    YRDA S 
Sbjct: 170 VDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSY 229

Query: 231 GAVNLYHVREDG 242
               +  V E G
Sbjct: 230 NRFQIATVTEKG 241


>gi|22538465 proteasome beta 3 subunit [Homo sapiens]
          Length = 205

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 43/187 (22%), Positives = 87/187 (46%), Gaps = 3/187 (1%)

Query: 58  HGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117
           +G   +A K ++ V +AAD R    A + +   +K+  +   L   +AG A D     + 
Sbjct: 7   NGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQR 66

Query: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR--GPGLYYVDS 175
           L  +  +YEL+   +I       ++AN++Y+ +        +I G D +   P +  +D 
Sbjct: 67  LKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDL 126

Query: 176 EGNRISGATFSV-GSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVN 234
            G  +    F V G+ +   YG+ +  +  +++ +  ++   +A+  A  RDA SG  V 
Sbjct: 127 IGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGVI 186

Query: 235 LYHVRED 241
           ++ + +D
Sbjct: 187 VHIIEKD 193


>gi|4506181 proteasome subunit alpha type 2 [Homo sapiens]
          Length = 234

 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 37/161 (22%), Positives = 72/161 (44%), Gaps = 5/161 (3%)

Query: 59  GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118
           G  ++  K  +GV++A + +  +  Y   ++V KV  I  ++    +G   D        
Sbjct: 32  GAPSVGIKAANGVVLATEKKQKSILY-DERSVHKVEPITKHIGLVYSGMGPDYRVLVHRA 90

Query: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRGPGLYYVD 174
            +  + Y L  +E I  A   + +A+++ +Y   G      +  +ICGW++  P L+  D
Sbjct: 91  RKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWNEGRPYLFQSD 150

Query: 175 SEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLA 215
             G   +    ++G   V     +++ Y+ DLE+E A   A
Sbjct: 151 PSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTA 191


>gi|23110942 proteasome alpha 5 subunit [Homo sapiens]
          Length = 241

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 33/162 (20%), Positives = 74/162 (45%), Gaps = 10/162 (6%)

Query: 59  GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118
           G+T +  +   GV +A + R T+   +   +++K++EI+ ++   M+G  AD        
Sbjct: 34  GSTAIGIQTSEGVCLAVEKRITS-PLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKA 92

Query: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTM---------ICGWDKRGPG 169
             + + +     E ++V + ++ ++N+  Q+       G M           G D++GP 
Sbjct: 93  RVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGPQ 152

Query: 170 LYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQA 211
           L+++D  G  +     ++GS S  A   +   Y   + +++A
Sbjct: 153 LFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEA 194


>gi|4506189 proteasome alpha 7 subunit [Homo sapiens]
          Length = 248

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 39/194 (20%), Positives = 86/194 (44%), Gaps = 9/194 (4%)

Query: 59  GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118
           G+T +  + R  V++  + ++ A      +TV+K+  ++  +    AG  AD        
Sbjct: 29  GSTAVGVRGRDIVVLGVEKKSVAKLQ-DERTVRKICALDDNVCMAFAGLTADARIVINRA 87

Query: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRG-PGLYYV 173
             +C+ + L  ++ ++V   ++ +A++  +Y          +  +I G+D  G P LY  
Sbjct: 88  RVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQT 147

Query: 174 DSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGA- 232
           D  G   +    ++G G+      +++ Y+   E  +  DL  + + +A      SGG  
Sbjct: 148 DPSGTYHAWKANAIGRGAKSVREFLEKNYTD--EAIETDDLTIKLVIKALLEVVQSGGKN 205

Query: 233 VNLYHVREDGWIRV 246
           + L  +R D  +++
Sbjct: 206 IELAVMRRDQSLKI 219


>gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens]
          Length = 250

 Score = 36.6 bits (83), Expect = 0.023
 Identities = 38/205 (18%), Positives = 90/205 (43%), Gaps = 13/205 (6%)

Query: 59  GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118
           G+T +  +  + V++  + ++ A      +TV+K+  ++ ++    AG  AD        
Sbjct: 31  GSTAVGIRGTNIVVLGVEKKSVAKLQ-DERTVRKICALDDHVCMAFAGLTADARVVINRA 89

Query: 119 ARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRG-PGLYYV 173
             +C+ ++L  ++ ++V   ++ +A +  +Y          +  +I G+D  G   LY  
Sbjct: 90  RVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQT 149

Query: 174 DSEGNRISGATFSVGSGSVYAYGVMDRGYSYD--LEVEQAYDLARRAIYQATYRDAYSGG 231
           D  G   +    ++G  +      +++ Y+ D      +A  LA +A+ +       SGG
Sbjct: 150 DPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAIKLAIKALLEV----VQSGG 205

Query: 232 A-VNLYHVREDGWIRVSSDNVADLH 255
             + L  +R +  +++ S    +L+
Sbjct: 206 KNIELAIIRRNQPLKMFSAKEVELY 230


>gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens]
          Length = 263

 Score = 34.7 bits (78), Expect = 0.087
 Identities = 32/153 (20%), Positives = 64/153 (41%), Gaps = 7/153 (4%)

Query: 59  GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118
           G+ T+  K +   ++ A  RA +    A Q  KK++ ++ ++  ++AG  AD       +
Sbjct: 32  GSATVGLKSKTHAVLVALKRAQS-ELAAHQ--KKILHVDNHIGISIAGLTADARLLCNFM 88

Query: 119 ARQCRIYELRNKERISVAAASKLLANMVY----QYKGMGLSMGTMICGWDKRGPGLYYVD 174
            ++C          + V+    L+ +       +Y      +G +I G+D  GP ++   
Sbjct: 89  RQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPHIFQTC 148

Query: 175 SEGNRISGATFSVGSGSVYAYGVMDRGYSYDLE 207
              N       S+G+ S  A   ++R  S  +E
Sbjct: 149 PSANYFDCRAMSIGARSQSARTYLERHMSEFME 181


>gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens]
          Length = 269

 Score = 34.7 bits (78), Expect = 0.087
 Identities = 32/153 (20%), Positives = 64/153 (41%), Gaps = 7/153 (4%)

Query: 59  GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLL 118
           G+ T+  K +   ++ A  RA +    A Q  KK++ ++ ++  ++AG  AD       +
Sbjct: 38  GSATVGLKSKTHAVLVALKRAQS-ELAAHQ--KKILHVDNHIGISIAGLTADARLLCNFM 94

Query: 119 ARQCRIYELRNKERISVAAASKLLANMVY----QYKGMGLSMGTMICGWDKRGPGLYYVD 174
            ++C          + V+    L+ +       +Y      +G +I G+D  GP ++   
Sbjct: 95  RQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPHIFQTC 154

Query: 175 SEGNRISGATFSVGSGSVYAYGVMDRGYSYDLE 207
              N       S+G+ S  A   ++R  S  +E
Sbjct: 155 PSANYFDCRAMSIGARSQSARTYLERHMSEFME 187


>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
          Length = 1051

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 24/90 (26%), Positives = 35/90 (38%), Gaps = 9/90 (10%)

Query: 163 WDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVM---------DRGYSYDLEVEQAYD 213
           WD         + +GN   G T  VGS  ++   +            G  + L  E   D
Sbjct: 232 WDLSEYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGD 291

Query: 214 LARRAIYQATYRDAYSGGAVNLYHVREDGW 243
           L RR + + +   AY G A+ L  +  DGW
Sbjct: 292 LRRRQVLEGSQVGAYFGSAIALADLNNDGW 321


>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
          Length = 1066

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 24/90 (26%), Positives = 35/90 (38%), Gaps = 9/90 (10%)

Query: 163 WDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVM---------DRGYSYDLEVEQAYD 213
           WD         + +GN   G T  VGS  ++   +            G  + L  E   D
Sbjct: 232 WDLSEYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGD 291

Query: 214 LARRAIYQATYRDAYSGGAVNLYHVREDGW 243
           L RR + + +   AY G A+ L  +  DGW
Sbjct: 292 LRRRQVLEGSQVGAYFGSAIALADLNNDGW 321


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 29.3 bits (64), Expect = 3.7
 Identities = 30/105 (28%), Positives = 41/105 (39%), Gaps = 19/105 (18%)

Query: 170 LYYVDSEGNRISGA-TFSVGSGSVYAYGVMDRG-------YSYDLEVEQAYDLARRAIYQ 221
           LY   S  N  +G  T  VG    +AY V  +G       Y  ++     YD      Y+
Sbjct: 598 LYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDE-----YK 652

Query: 222 ATYRDAYSGGAVNLYHVREDGWIRVSSDNVADL------HEKYSG 260
             Y D  SGGAV      +  W+++ SD    L      H  +SG
Sbjct: 653 KGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSG 697


>gi|169217837 PREDICTED: similar to hCG1773549 [Homo sapiens]
          Length = 120

 Score = 28.9 bits (63), Expect = 4.8
 Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 1/49 (2%)

Query: 43  APGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVK 91
           APG G+    GI  + GT   A KF+  V + AD ++T+ AY+   +++
Sbjct: 59  APGQGLEWMGGIIPIFGTANYAQKFQGRVTITAD-KSTSTAYMELSSLR 106


>gi|34577122 nuclear factor kappa-B, subunit 1 [Homo sapiens]
          Length = 969

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 6/56 (10%)

Query: 17  GFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVI 72
           G FG GG       G G+ S G   + P +G P   GI    GTT      +HG +
Sbjct: 387 GMFGSGGG------GGGTGSTGPGYSFPHYGFPTYGGITFHPGTTKSNAGMKHGTM 436


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,750,528
Number of Sequences: 37866
Number of extensions: 415867
Number of successful extensions: 907
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 879
Number of HSP's gapped (non-prelim): 25
length of query: 263
length of database: 18,247,518
effective HSP length: 100
effective length of query: 163
effective length of database: 14,460,918
effective search space: 2357129634
effective search space used: 2357129634
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.