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Search of human proteins with 4505997
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505997 protein phosphatase 1D [Homo sapiens]
(605 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505997 protein phosphatase 1D [Homo sapiens] 1231 0.0
gi|122937199 protein phosphatase 1B-like [Homo sapiens] 96 7e-20
gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens] 87 4e-17
gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens] 87 4e-17
gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens] 87 4e-17
gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens] 86 8e-17
gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens] 86 8e-17
gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens] 86 8e-17
gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens] 86 8e-17
gi|30089948 protein phosphatase 1E [Homo sapiens] 81 3e-15
gi|7661862 protein phosphatase 1F [Homo sapiens] 78 2e-14
gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens] 74 4e-13
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho... 71 3e-12
gi|13540531 integrin-linked kinase-associated protein phosphatas... 70 4e-12
gi|4505999 protein phosphatase 1G [Homo sapiens] 70 7e-12
gi|29826282 protein phosphatase 1G [Homo sapiens] 70 7e-12
gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit ... 60 6e-09
gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit... 60 6e-09
gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit... 60 6e-09
gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit... 60 6e-09
gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit... 60 6e-09
gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo... 54 3e-07
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 42 0.001
gi|145275193 specifically androgen-regulated protein isoform 2 [... 40 0.006
gi|145275189 specifically androgen-regulated protein isoform 1 [... 40 0.006
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 37 0.040
gi|82546824 forkhead box K1 [Homo sapiens] 37 0.040
gi|91208437 GEM interacting protein [Homo sapiens] 37 0.040
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 37 0.052
gi|110832843 TBP-associated factor 4 [Homo sapiens] 36 0.12
>gi|4505997 protein phosphatase 1D [Homo sapiens]
Length = 605
Score = 1231 bits (3186), Expect = 0.0
Identities = 605/605 (100%), Positives = 605/605 (100%)
Query: 1 MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPG 60
MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPG
Sbjct: 1 MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPG 60
Query: 61 GEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAREHL 120
GEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAREHL
Sbjct: 61 GEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAREHL 120
Query: 121 WGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVII 180
WGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVII
Sbjct: 121 WGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVII 180
Query: 181 RGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSG 240
RGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSG
Sbjct: 181 RGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSG 240
Query: 241 VNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHT 300
VNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHT
Sbjct: 241 VNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHT 300
Query: 301 LDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQ 360
LDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQ
Sbjct: 301 LDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQ 360
Query: 361 RMLRADNTSAIVICISPEVDNQGNFTNEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVK 420
RMLRADNTSAIVICISPEVDNQGNFTNEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVK
Sbjct: 361 RMLRADNTSAIVICISPEVDNQGNFTNEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVK 420
Query: 421 SLEEDPWPRVNSKDHIPALVRSNAFSENFLEVSAEIARENVQGVVIPSKDPEPLEENCAK 480
SLEEDPWPRVNSKDHIPALVRSNAFSENFLEVSAEIARENVQGVVIPSKDPEPLEENCAK
Sbjct: 421 SLEEDPWPRVNSKDHIPALVRSNAFSENFLEVSAEIARENVQGVVIPSKDPEPLEENCAK 480
Query: 481 ALTLRIHDSLNNSLPIGLVPTNSTNTVMDQKNLKMSTPGQMKAQEIERTPPTNFKRTLEE 540
ALTLRIHDSLNNSLPIGLVPTNSTNTVMDQKNLKMSTPGQMKAQEIERTPPTNFKRTLEE
Sbjct: 481 ALTLRIHDSLNNSLPIGLVPTNSTNTVMDQKNLKMSTPGQMKAQEIERTPPTNFKRTLEE 540
Query: 541 SNSGPLMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTMRRRLRGQKKIGNPLLHQHRK 600
SNSGPLMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTMRRRLRGQKKIGNPLLHQHRK
Sbjct: 541 SNSGPLMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTMRRRLRGQKKIGNPLLHQHRK 600
Query: 601 TVCVC 605
TVCVC
Sbjct: 601 TVCVC 605
>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
Length = 430
Score = 96.3 bits (238), Expect = 7e-20
Identities = 77/229 (33%), Positives = 114/229 (49%), Gaps = 52/229 (22%)
Query: 99 AFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLA 158
A FAV DGHGG AA+F HL G + ++ G SEP V A+R+ FL+ A + +
Sbjct: 97 ALFAVLDGHGGARAARFGARHLPGHVLQELGPEPSEPEGVREALRRAFLS---ADERLRS 153
Query: 159 EWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEV---TQ 215
WP+ TG G TA V+++ +Y+AH GDS VL RA V T+
Sbjct: 154 LWPRVETG-----GCTAVVLLVSPRFLYLAHCGDSRAVLS----------RAGAVAFSTE 198
Query: 216 DHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARAL 275
DH+P P+ERERI GG++ +R R+ + LAV+RAL
Sbjct: 199 DHRPLRPRERERIHAAGGTI-----------RRRRVEGS--------------LAVSRAL 233
Query: 276 GDLWSYDFFSGE----FVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMI 320
GD ++Y G +VS EP+ + + ++++L SDG+W+ +
Sbjct: 234 GD-FTYKEAPGRPPELQLVSAEPEVAALARQAE-DEFMLLASDGVWDTV 280
>gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]
Length = 382
Score = 87.0 bits (214), Expect = 4e-17
Identities = 87/292 (29%), Positives = 130/292 (44%), Gaps = 53/292 (18%)
Query: 97 SVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKK 156
S +FFAV DGH G + A++ EHL I + F S A ++ G L + +
Sbjct: 52 SWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEH 111
Query: 157 LAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQD 216
+ + G SG+TA V+I Y + GDS +L + K F TQD
Sbjct: 112 MRVMSEKKHG-ADRSGSTAVGVLISPQHTYFINCGDSRGLL--CRNRKVHF-----FTQD 163
Query: 217 HKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALG 276
HKP P E+ERI+ GGSVM + RV NG LAV+RALG
Sbjct: 164 HKPSNPLEKERIQNAGGSVM----IQRV---------NGS------------LAVSRALG 198
Query: 277 DLWSYDFFSG----EFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQ 332
D + Y G E +VSPEP+ + ++IIL DG+W+++ ++ + +
Sbjct: 199 D-FDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSR 257
Query: 333 EEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVIC------ISPE 378
E + + + +V+ L + + DN S I+IC +SPE
Sbjct: 258 LE----VTDDLEKVCNEVVDTCLYKGSR-----DNMSVILICFPNAPKVSPE 300
>gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
Length = 324
Score = 87.0 bits (214), Expect = 4e-17
Identities = 87/292 (29%), Positives = 130/292 (44%), Gaps = 53/292 (18%)
Query: 97 SVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKK 156
S +FFAV DGH G + A++ EHL I + F S A ++ G L + +
Sbjct: 52 SWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEH 111
Query: 157 LAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQD 216
+ + G SG+TA V+I Y + GDS +L + K F TQD
Sbjct: 112 MRVMSEKKHG-ADRSGSTAVGVLISPQHTYFINCGDSRGLL--CRNRKVHF-----FTQD 163
Query: 217 HKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALG 276
HKP P E+ERI+ GGSVM + RV NG LAV+RALG
Sbjct: 164 HKPSNPLEKERIQNAGGSVM----IQRV---------NGS------------LAVSRALG 198
Query: 277 DLWSYDFFSG----EFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQ 332
D + Y G E +VSPEP+ + ++IIL DG+W+++ ++ + +
Sbjct: 199 D-FDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSR 257
Query: 333 EEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVIC------ISPE 378
E + + + +V+ L + + DN S I+IC +SPE
Sbjct: 258 LE----VTDDLEKVCNEVVDTCLYKGSR-----DNMSVILICFPNAPKVSPE 300
>gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]
Length = 455
Score = 87.0 bits (214), Expect = 4e-17
Identities = 87/292 (29%), Positives = 130/292 (44%), Gaps = 53/292 (18%)
Query: 97 SVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKK 156
S +FFAV DGH G + A++ EHL I + F S A ++ G L + +
Sbjct: 125 SWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEH 184
Query: 157 LAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQD 216
+ + G SG+TA V+I Y + GDS +L + K F TQD
Sbjct: 185 MRVMSEKKHG-ADRSGSTAVGVLISPQHTYFINCGDSRGLL--CRNRKVHF-----FTQD 236
Query: 217 HKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALG 276
HKP P E+ERI+ GGSVM + RV NG LAV+RALG
Sbjct: 237 HKPSNPLEKERIQNAGGSVM----IQRV---------NGS------------LAVSRALG 271
Query: 277 DLWSYDFFSG----EFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQ 332
D + Y G E +VSPEP+ + ++IIL DG+W+++ ++ + +
Sbjct: 272 D-FDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSR 330
Query: 333 EEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVIC------ISPE 378
E + + + +V+ L + + DN S I+IC +SPE
Sbjct: 331 LE----VTDDLEKVCNEVVDTCLYKGSR-----DNMSVILICFPNAPKVSPE 373
>gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]
Length = 380
Score = 86.3 bits (212), Expect = 8e-17
Identities = 87/302 (28%), Positives = 137/302 (45%), Gaps = 69/302 (22%)
Query: 99 AFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPA---------KVCAAIRKGFLAC 149
+FFAV DGH G A + HL I + F ++ + V IR GFL
Sbjct: 54 SFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFL-- 111
Query: 150 HLAMWKKLAEWPKTMTGLPS---TSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDD 206
K+ E+ + + L + SG+TA V+I +Y + GDS VL
Sbjct: 112 ------KIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNG----- 160
Query: 207 FVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI 266
+ TQDHKP P+E+ERI+ GGSVM + RV NG
Sbjct: 161 --QVCFSTQDHKPCNPREKERIQNAGGSVM----IQRV---------NGS---------- 195
Query: 267 PFLAVARALGDLWSYDFFSG----EFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322
LAV+RALGD + Y G E +VSPEP+ L ++ ++IIL DG+W+++
Sbjct: 196 --LAVSRALGD-YDYKCVDGKGPTEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSN 251
Query: 323 QDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICIS--PEVD 380
++ + + E + + ++ +V+ L + + DN S +++C S P+V
Sbjct: 252 EELCEYVKSRLE----VSDDLENVCNWVVDTCLHKGSR-----DNMSIVLVCFSNAPKVS 302
Query: 381 NQ 382
++
Sbjct: 303 DE 304
>gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]
Length = 327
Score = 86.3 bits (212), Expect = 8e-17
Identities = 87/302 (28%), Positives = 137/302 (45%), Gaps = 69/302 (22%)
Query: 99 AFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPA---------KVCAAIRKGFLAC 149
+FFAV DGH G A + HL I + F ++ + V IR GFL
Sbjct: 54 SFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFL-- 111
Query: 150 HLAMWKKLAEWPKTMTGLPS---TSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDD 206
K+ E+ + + L + SG+TA V+I +Y + GDS VL
Sbjct: 112 ------KIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNG----- 160
Query: 207 FVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI 266
+ TQDHKP P+E+ERI+ GGSVM + RV NG
Sbjct: 161 --QVCFSTQDHKPCNPREKERIQNAGGSVM----IQRV---------NGS---------- 195
Query: 267 PFLAVARALGDLWSYDFFSG----EFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322
LAV+RALGD + Y G E +VSPEP+ L ++ ++IIL DG+W+++
Sbjct: 196 --LAVSRALGD-YDYKCVDGKGPTEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSN 251
Query: 323 QDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICIS--PEVD 380
++ + + E + + ++ +V+ L + + DN S +++C S P+V
Sbjct: 252 EELCEYVKSRLE----VSDDLENVCNWVVDTCLHKGSR-----DNMSIVLVCFSNAPKVS 302
Query: 381 NQ 382
++
Sbjct: 303 DE 304
>gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]
Length = 387
Score = 86.3 bits (212), Expect = 8e-17
Identities = 87/302 (28%), Positives = 137/302 (45%), Gaps = 69/302 (22%)
Query: 99 AFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPA---------KVCAAIRKGFLAC 149
+FFAV DGH G A + HL I + F ++ + V IR GFL
Sbjct: 54 SFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFL-- 111
Query: 150 HLAMWKKLAEWPKTMTGLPS---TSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDD 206
K+ E+ + + L + SG+TA V+I +Y + GDS VL
Sbjct: 112 ------KIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNG----- 160
Query: 207 FVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI 266
+ TQDHKP P+E+ERI+ GGSVM + RV NG
Sbjct: 161 --QVCFSTQDHKPCNPREKERIQNAGGSVM----IQRV---------NGS---------- 195
Query: 267 PFLAVARALGDLWSYDFFSG----EFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322
LAV+RALGD + Y G E +VSPEP+ L ++ ++IIL DG+W+++
Sbjct: 196 --LAVSRALGD-YDYKCVDGKGPTEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSN 251
Query: 323 QDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICIS--PEVD 380
++ + + E + + ++ +V+ L + + DN S +++C S P+V
Sbjct: 252 EELCEYVKSRLE----VSDDLENVCNWVVDTCLHKGSR-----DNMSIVLVCFSNAPKVS 302
Query: 381 NQ 382
++
Sbjct: 303 DE 304
>gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]
Length = 479
Score = 86.3 bits (212), Expect = 8e-17
Identities = 87/302 (28%), Positives = 137/302 (45%), Gaps = 69/302 (22%)
Query: 99 AFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPA---------KVCAAIRKGFLAC 149
+FFAV DGH G A + HL I + F ++ + V IR GFL
Sbjct: 54 SFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFL-- 111
Query: 150 HLAMWKKLAEWPKTMTGLPS---TSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDD 206
K+ E+ + + L + SG+TA V+I +Y + GDS VL
Sbjct: 112 ------KIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNG----- 160
Query: 207 FVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI 266
+ TQDHKP P+E+ERI+ GGSVM + RV NG
Sbjct: 161 --QVCFSTQDHKPCNPREKERIQNAGGSVM----IQRV---------NGS---------- 195
Query: 267 PFLAVARALGDLWSYDFFSG----EFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322
LAV+RALGD + Y G E +VSPEP+ L ++ ++IIL DG+W+++
Sbjct: 196 --LAVSRALGD-YDYKCVDGKGPTEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSN 251
Query: 323 QDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICIS--PEVD 380
++ + + E + + ++ +V+ L + + DN S +++C S P+V
Sbjct: 252 EELCEYVKSRLE----VSDDLENVCNWVVDTCLHKGSR-----DNMSIVLVCFSNAPKVS 302
Query: 381 NQ 382
++
Sbjct: 303 DE 304
>gi|30089948 protein phosphatase 1E [Homo sapiens]
Length = 755
Score = 80.9 bits (198), Expect = 3e-15
Identities = 82/275 (29%), Positives = 126/275 (45%), Gaps = 55/275 (20%)
Query: 99 AFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLA 158
A+FAV DGHGG +AA +A HL + +Q+ F +C A R + + K
Sbjct: 267 AYFAVFDGHGGVDAAIYASIHLHVNLVRQEMFPHDPAEALCRAFR---VTDERFVQKAAR 323
Query: 159 EWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHK 218
E GTT V IRG ++VA VGDS V+L + +AVE+ + HK
Sbjct: 324 E--------SLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKG-------QAVELMKPHK 368
Query: 219 PELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDL 278
P+ E++RIE LGG V+ G RV NG L+V+RA+GD
Sbjct: 369 PDREDEKQRIEALGGCVV-WFGAWRV---------NGS------------LSVSRAIGDA 406
Query: 279 WSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYL 338
+ G + D++ LD + Y+IL DG ++ + P +A+ + D +L
Sbjct: 407 EHKPYICG------DADSASTVLDGTE-DYLILACDGFYDTVNPDEAVKVVSD-----HL 454
Query: 339 MGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVI 373
+G S M+ ++ + R +DN + IV+
Sbjct: 455 KENNGDS--SMVAHKLVASARDAG-SSDNITVIVV 486
>gi|7661862 protein phosphatase 1F [Homo sapiens]
Length = 454
Score = 78.2 bits (191), Expect = 2e-14
Identities = 67/232 (28%), Positives = 107/232 (46%), Gaps = 47/232 (20%)
Query: 99 AFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLA 158
A+FAV DGHGG +AA++A H+ +Q P A+R+ F M+ + A
Sbjct: 192 AYFAVFDGHGGVDAARYAAVHVHTNAARQPEL----PTDPEGALREAFRRTD-QMFLRKA 246
Query: 159 EWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHK 218
+ + SGTT +I G ++VA +GDS V+L Q + V++ + H+
Sbjct: 247 KRERLQ------SGTTGVCALIAGATLHVAWLGDSQVILVQQG-------QVVKLMEPHR 293
Query: 219 PELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDL 278
PE E+ RIE LGG V + W+ NG LAV+RA+GD+
Sbjct: 294 PERQDEKARIEALGGFVSHMD-----CWR-----VNGT------------LAVSRAIGDV 331
Query: 279 WSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQ 330
+ + SGE + T Y++L DG ++++P Q+ + + Q
Sbjct: 332 FQKPYVSGEADAASRALTG-------SEDYLLLACDGFFDVVPHQEVVGLVQ 376
>gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]
Length = 360
Score = 73.9 bits (180), Expect = 4e-13
Identities = 64/243 (26%), Positives = 113/243 (46%), Gaps = 43/243 (17%)
Query: 99 AFFAVCDGHGGREAAQFAREHLWGFIKKQ-KGFTSSEPAKVCA---AIRKGFLACHLAMW 154
+ F + DGHGG AA++ + L +K+ + + + V + + + L+ M
Sbjct: 122 SIFGIFDGHGGETAAEYVKSRLPEALKQHLQDYEKDKENSVLSYQTILEQQILSIDREML 181
Query: 155 KKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVT 214
+KL T +GTT + ++ + VA+VGDS VL +D A+ ++
Sbjct: 182 EKL-------TVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDG------NAIPLS 228
Query: 215 QDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARA 274
DHKP KER+RI+ GG + + NG R + LA++R+
Sbjct: 229 HDHKPYQLKERKRIKRAGGFI----------------SFNGSWRVQGI------LAMSRS 266
Query: 275 LGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEE 334
LGD + VV P+PD LD + +++IL SDGLW+ ++A+ +++ +
Sbjct: 267 LGDYPLKNLN----VVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLD 322
Query: 335 KKY 337
+ +
Sbjct: 323 EPH 325
>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
sapiens]
Length = 372
Score = 70.9 bits (172), Expect = 3e-12
Identities = 75/253 (29%), Positives = 111/253 (43%), Gaps = 53/253 (20%)
Query: 98 VAFFAVCDGHGGREAAQFAREH----LWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAM 153
V +FAV DGHGG AA F H + + K+K + + FL A
Sbjct: 120 VLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLET--------LLTLAFLEIDKA- 170
Query: 154 WKKLAEWPKTMTGLPSTSGTTASVVIIR-GMKMYVAHVGDSGVVLGIQDDPKDDFVRAVE 212
+ A T L TSGTTA+V ++R G+++ VA VGDS +L + P ++
Sbjct: 171 FSSHARLSADATLL--TSGTTATVALLRDGIELVVASVGDSRAILCRKGKP-------MK 221
Query: 213 VTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTH-NGPVRRSTVIDQIPFLAV 271
+T DH PE E+ERI+ GG V W H NG LA+
Sbjct: 222 LTIDHTPERKDEKERIKKCGGF---------VAWNSLGQPHVNGR------------LAM 260
Query: 272 ARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQ---DAISM 328
R++GDL D + + EP+T L +++L +DG+ M+ Q D ++
Sbjct: 261 TRSIGDL---DLKTSGVIA--EPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQ 315
Query: 329 CQDQEEKKYLMGE 341
C D E + + E
Sbjct: 316 CHDPNEAAHAVTE 328
>gi|13540531 integrin-linked kinase-associated protein phosphatase
2C [Homo sapiens]
Length = 392
Score = 70.5 bits (171), Expect = 4e-12
Identities = 75/297 (25%), Positives = 132/297 (44%), Gaps = 54/297 (18%)
Query: 92 CRRRSS----VAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFL 147
CR SS V++FAV DGHGG A++FA ++L + P ++ K
Sbjct: 135 CRPPSSLITRVSYFAVFDGHGGIRASKFAAQNL------HQNLIRKFPKGDVISVEKTVK 188
Query: 148 ACHLAMWKKLAE--WPKTMTGLPS-TSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPK 204
C L +K E + + P+ G+TA+ V+ +Y+A++GDS +L ++
Sbjct: 189 RCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEES 248
Query: 205 DDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVID 264
A+ ++++H P +ER RI+ GG+V + RV
Sbjct: 249 QKHA-ALSLSKEHNPTQYEERMRIQKAGGNVRD----GRV-------------------- 283
Query: 265 QIPFLAVARALGDLWSYDFFSGEFV---VSPEPDTSVHTLDPQKHKYIILGSDGLWNMIP 321
+ L V+R++GD G++ V+ PD L P ++I+L DGL+ +
Sbjct: 284 -LGVLEVSRSIGD--------GQYKRCGVTSVPDIRRCQLTPND-RFILLACDGLFKVFT 333
Query: 322 PQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLR---ADNTSAIVICI 375
P++A++ E + + G+S A A R + ++ ADN + +V+ I
Sbjct: 334 PEEAVNFILSCLEDEKIQTREGKSAADARYEAACNRLANKAVQRGSADNVTVMVVRI 390
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 69.7 bits (169), Expect = 7e-12
Identities = 60/215 (27%), Positives = 99/215 (46%), Gaps = 38/215 (17%)
Query: 169 STSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERI 228
S SGTTA V +IRG ++ VA+ GDS V+ + +A++++ DHKPE E RI
Sbjct: 325 SDSGTTAVVALIRGKQLIVANAGDSRCVVS-------EAGKALDMSYDHKPEDEVELARI 377
Query: 229 EGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLW---SYDFFS 285
+ GG V VN L ++RA+GD + + +
Sbjct: 378 KNAGGKVTMDGRVNGG------------------------LNLSRAIGDHFYKRNKNLPP 413
Query: 286 GEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHG-- 343
E ++S PD V TL H+++++ DG+WN++ Q+ + Q + ++ GE
Sbjct: 414 EEQMISALPDIKVLTLTDD-HEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLL 472
Query: 344 QSCAKMLVNRALG-RWRQRMLRADNTSAIVICISP 377
S + L+++ L DN + I+IC P
Sbjct: 473 SSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKP 507
Score = 39.7 bits (91), Expect = 0.008
Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 15/91 (16%)
Query: 58 LPGGEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAR 117
LP G + +G V+ +A + +P+ S A F+V DGHGG E A +
Sbjct: 25 LPYGFSAMQGWRVSMEDAHNCIPELD------------SETAMFSVYDGHGGEEVALYCA 72
Query: 118 EHLWGFIKKQKGFTSSEPAKVCAAIRKGFLA 148
++L IK QK + + K+ A+ FLA
Sbjct: 73 KYLPDIIKDQKAY---KEGKLQKALEDAFLA 100
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 69.7 bits (169), Expect = 7e-12
Identities = 60/215 (27%), Positives = 99/215 (46%), Gaps = 38/215 (17%)
Query: 169 STSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERI 228
S SGTTA V +IRG ++ VA+ GDS V+ + +A++++ DHKPE E RI
Sbjct: 325 SDSGTTAVVALIRGKQLIVANAGDSRCVVS-------EAGKALDMSYDHKPEDEVELARI 377
Query: 229 EGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLW---SYDFFS 285
+ GG V VN L ++RA+GD + + +
Sbjct: 378 KNAGGKVTMDGRVNGG------------------------LNLSRAIGDHFYKRNKNLPP 413
Query: 286 GEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHG-- 343
E ++S PD V TL H+++++ DG+WN++ Q+ + Q + ++ GE
Sbjct: 414 EEQMISALPDIKVLTLTDD-HEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLL 472
Query: 344 QSCAKMLVNRALG-RWRQRMLRADNTSAIVICISP 377
S + L+++ L DN + I+IC P
Sbjct: 473 SSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKP 507
Score = 39.7 bits (91), Expect = 0.008
Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 15/91 (16%)
Query: 58 LPGGEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAR 117
LP G + +G V+ +A + +P+ S A F+V DGHGG E A +
Sbjct: 25 LPYGFSAMQGWRVSMEDAHNCIPELD------------SETAMFSVYDGHGGEEVALYCA 72
Query: 118 EHLWGFIKKQKGFTSSEPAKVCAAIRKGFLA 148
++L IK QK + + K+ A+ FLA
Sbjct: 73 KYLPDIIKDQKAY---KEGKLQKALEDAFLA 100
>gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 60.1 bits (144), Expect = 6e-09
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 56/202 (27%)
Query: 171 SGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEG 230
SG TA V + G+ ++VA+ GDS +LG+Q++ D AV ++ DH + +E ER++
Sbjct: 270 SGATACVAHVDGVDLHVANTGDSRAMLGVQEE--DGSWSAVTLSNDHNAQNERELERLK- 326
Query: 231 LGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI-PFLAVARALGDL---WSYD---- 282
+ P+ V++ ++ + PF RA GD+ WS D
Sbjct: 327 ---------------LEHPKSEAKSVVKQDRLLGLLMPF----RAFGDVKFKWSIDLQKR 367
Query: 283 ----------------FFSGEFVVSP----EPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322
F + P EP+ + H L PQ K+++L +DGLW +
Sbjct: 368 VIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQD-KFLVLATDGLWETMHR 426
Query: 323 QDAISMCQDQEEKKYLMGEHGQ 344
QD + + + YL G H Q
Sbjct: 427 QDVVRIVGE-----YLTGMHHQ 443
>gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 60.1 bits (144), Expect = 6e-09
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 56/202 (27%)
Query: 171 SGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEG 230
SG TA V + G+ ++VA+ GDS +LG+Q++ D AV ++ DH + +E ER++
Sbjct: 270 SGATACVAHVDGVDLHVANTGDSRAMLGVQEE--DGSWSAVTLSNDHNAQNERELERLK- 326
Query: 231 LGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI-PFLAVARALGDL---WSYD---- 282
+ P+ V++ ++ + PF RA GD+ WS D
Sbjct: 327 ---------------LEHPKSEAKSVVKQDRLLGLLMPF----RAFGDVKFKWSIDLQKR 367
Query: 283 ----------------FFSGEFVVSP----EPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322
F + P EP+ + H L PQ K+++L +DGLW +
Sbjct: 368 VIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQD-KFLVLATDGLWETMHR 426
Query: 323 QDAISMCQDQEEKKYLMGEHGQ 344
QD + + + YL G H Q
Sbjct: 427 QDVVRIVGE-----YLTGMHHQ 443
>gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 60.1 bits (144), Expect = 6e-09
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 56/202 (27%)
Query: 171 SGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEG 230
SG TA V + G+ ++VA+ GDS +LG+Q++ D AV ++ DH + +E ER++
Sbjct: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEE--DGSWSAVTLSNDHNAQNERELERLK- 351
Query: 231 LGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI-PFLAVARALGDL---WSYD---- 282
+ P+ V++ ++ + PF RA GD+ WS D
Sbjct: 352 ---------------LEHPKSEAKSVVKQDRLLGLLMPF----RAFGDVKFKWSIDLQKR 392
Query: 283 ----------------FFSGEFVVSP----EPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322
F + P EP+ + H L PQ K+++L +DGLW +
Sbjct: 393 VIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQD-KFLVLATDGLWETMHR 451
Query: 323 QDAISMCQDQEEKKYLMGEHGQ 344
QD + + + YL G H Q
Sbjct: 452 QDVVRIVGE-----YLTGMHHQ 468
>gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 60.1 bits (144), Expect = 6e-09
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 56/202 (27%)
Query: 171 SGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEG 230
SG TA V + G+ ++VA+ GDS +LG+Q++ D AV ++ DH + +E ER++
Sbjct: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEE--DGSWSAVTLSNDHNAQNERELERLK- 351
Query: 231 LGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI-PFLAVARALGDL---WSYD---- 282
+ P+ V++ ++ + PF RA GD+ WS D
Sbjct: 352 ---------------LEHPKSEAKSVVKQDRLLGLLMPF----RAFGDVKFKWSIDLQKR 392
Query: 283 ----------------FFSGEFVVSP----EPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322
F + P EP+ + H L PQ K+++L +DGLW +
Sbjct: 393 VIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQD-KFLVLATDGLWETMHR 451
Query: 323 QDAISMCQDQEEKKYLMGEHGQ 344
QD + + + YL G H Q
Sbjct: 452 QDVVRIVGE-----YLTGMHHQ 468
>gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 1 [Homo sapiens]
Length = 596
Score = 60.1 bits (144), Expect = 6e-09
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 56/202 (27%)
Query: 171 SGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEG 230
SG TA V + G+ ++VA+ GDS +LG+Q++ D AV ++ DH + +E ER++
Sbjct: 329 SGATACVAHVDGVDLHVANTGDSRAMLGVQEE--DGSWSAVTLSNDHNAQNERELERLK- 385
Query: 231 LGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI-PFLAVARALGDL---WSYD---- 282
+ P+ V++ ++ + PF RA GD+ WS D
Sbjct: 386 ---------------LEHPKSEAKSVVKQDRLLGLLMPF----RAFGDVKFKWSIDLQKR 426
Query: 283 ----------------FFSGEFVVSP----EPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322
F + P EP+ + H L PQ K+++L +DGLW +
Sbjct: 427 VIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQD-KFLVLATDGLWETMHR 485
Query: 323 QDAISMCQDQEEKKYLMGEHGQ 344
QD + + + YL G H Q
Sbjct: 486 QDVVRIVGE-----YLTGMHHQ 502
>gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo
sapiens]
Length = 529
Score = 54.3 bits (129), Expect = 3e-07
Identities = 44/184 (23%), Positives = 79/184 (42%), Gaps = 48/184 (26%)
Query: 171 SGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEG 230
SG TA + + G+ ++VA+ GD +LG+Q+D + + +T+DH
Sbjct: 265 SGATACMAHVDGIHLHVANAGDCRAILGVQED--NGMWSCLPLTRDH------------- 309
Query: 231 LGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDL---WS------- 280
+ N++ ++R+ + P + ++ L RA GD+ WS
Sbjct: 310 ---NAWNQAELSRLKREHPESEDRTIIMEDRLLG---VLIPCRAFGDVQLKWSKELQRSI 363
Query: 281 ------------YDFFSGEFVVSP----EPDTSVHTLDPQKHKYIILGSDGLWNMIPPQD 324
Y F + P EP+ + H L PQ K+++L SDGLW+M+ +D
Sbjct: 364 LERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQD-KFLVLASDGLWDMLSNED 422
Query: 325 AISM 328
+ +
Sbjct: 423 VVRL 426
>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
potassium channel 4 [Homo sapiens]
Length = 1203
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/117 (30%), Positives = 50/117 (42%), Gaps = 6/117 (5%)
Query: 4 LYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPGGEV 63
LYSL V G + ++ D + E + PS R +PLP PSP+A GG
Sbjct: 12 LYSLPQQV----GAKAWIMDEEEDAEEEGAGGRQDPSRRSIRLRPLPS-PSPSAAAGGTE 66
Query: 64 SGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAREHL 120
S + A+ A ++ P AG S C R R S+A G G + + HL
Sbjct: 67 S-RSSALGAADSEGPARGAGKSSTNGDCRRFRGSLASLGSRGGGSGGTGSGSSHGHL 122
>gi|145275193 specifically androgen-regulated protein isoform 2
[Homo sapiens]
Length = 355
Score = 40.0 bits (92), Expect = 0.006
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 4 LYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALP-GGE 62
L LG+ D+ G + + I P+ T + SP L+QP P + AA+P G+
Sbjct: 105 LEKLGLPQDQDEPGLHLSKPTSSI--RPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGK 162
Query: 63 VSGKGPAVAAREARDPLPDAGASPAPSRCCRRRS 96
+ PA A A+ PLP SPAP +S
Sbjct: 163 ALAQAPAPAPGPAQGPLP--MKSPAPGNVAASKS 194
>gi|145275189 specifically androgen-regulated protein isoform 1
[Homo sapiens]
Length = 601
Score = 40.0 bits (92), Expect = 0.006
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 4 LYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALP-GGE 62
L LG+ D+ G + + I P+ T + SP L+QP P + AA+P G+
Sbjct: 351 LEKLGLPQDQDEPGLHLSKPTSSI--RPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGK 408
Query: 63 VSGKGPAVAAREARDPLPDAGASPAPSRCCRRRS 96
+ PA A A+ PLP SPAP +S
Sbjct: 409 ALAQAPAPAPGPAQGPLP--MKSPAPGNVAASKS 440
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 37.4 bits (85), Expect = 0.040
Identities = 17/48 (35%), Positives = 27/48 (56%)
Query: 21 MEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPGGEVSGKGP 68
+++V +P P+A E P+P++S S+P P +P G VS GP
Sbjct: 1234 VKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGP 1281
>gi|82546824 forkhead box K1 [Homo sapiens]
Length = 733
Score = 37.4 bits (85), Expect = 0.040
Identities = 19/55 (34%), Positives = 26/55 (47%)
Query: 33 PTAEEKPSPRRSLSQPLPPRPSPAALPGGEVSGKGPAVAAREARDPLPDAGASPA 87
P A P+P + P PP P P LP G ++G G + + AGA+PA
Sbjct: 35 PAAAPPPAPAQPQPPPGPPPPPPPPLPPGAIAGAGSSGGSSGVSGDSAVAGAAPA 89
>gi|91208437 GEM interacting protein [Homo sapiens]
Length = 970
Score = 37.4 bits (85), Expect = 0.040
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 4/117 (3%)
Query: 21 MEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPGGEVSGKGPAVAAREARDPLP 80
M+++ Q P + P P + SQP PP P + P S GP + P
Sbjct: 759 MDELPQATEPPPQDSSPAPGPLTTSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHP 818
Query: 81 DAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAK 137
A + P+ +R VA DG GG ++Q + L G + +G S +P K
Sbjct: 819 TATPTEIPTPQSDQREDVA-EDTKDG-GGEVSSQGPEDSLLG--TQSRGHFSRQPVK 871
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 37.0 bits (84), Expect = 0.052
Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 8/66 (12%)
Query: 31 PEPTAEEKPSPRRSLSQPLPP--RPSPA------ALPGGEVSGKGPAVAAREARDPLPDA 82
P+ A P P+R +S PP R SP +L G P+ + REAR P P+
Sbjct: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK 680
Query: 83 GASPAP 88
SP+P
Sbjct: 681 RHSPSP 686
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 35.8 bits (81), Expect = 0.12
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 31 PEPTAEEKPSPRRSLSQPLPPRPSPAALPGGEVSG---KGPAVAAREARDPLPDAGASPA 87
P P A P+ + P PP P+ A P G +G PAV A AGA+PA
Sbjct: 255 PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA 314
Query: 88 PS 89
P+
Sbjct: 315 PA 316
Score = 30.0 bits (66), Expect = 6.4
Identities = 20/63 (31%), Positives = 25/63 (39%), Gaps = 7/63 (11%)
Query: 33 PTAEEKPSPRRSLSQPLPPRPSPAALPGGEVSGKGP-------AVAAREARDPLPDAGAS 85
P A+ +P P S P + A G E + GP A+AAR P P G
Sbjct: 122 PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG 181
Query: 86 PAP 88
P P
Sbjct: 182 PGP 184
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,029,200
Number of Sequences: 37866
Number of extensions: 1465881
Number of successful extensions: 8831
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 214
Number of HSP's that attempted gapping in prelim test: 8058
Number of HSP's gapped (non-prelim): 883
length of query: 605
length of database: 18,247,518
effective HSP length: 108
effective length of query: 497
effective length of database: 14,157,990
effective search space: 7036521030
effective search space used: 7036521030
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.