Guide to the Human Genome
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Search of human proteins with 4505441

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505441 natriuretic peptide receptor C/guanylate cyclase C
(atrionatriuretic peptide receptor C) [Homo sapiens]
         (540 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505441 natriuretic peptide receptor C/guanylate cyclase C (a...  1087   0.0  
gi|167830411 natriuretic peptide receptor 1 [Homo sapiens]            217   2e-56
gi|4580422 natriuretic peptide receptor B precursor [Homo sapiens]    195   1e-49
gi|134152694 guanylate cyclase 2F [Homo sapiens]                       56   7e-08
gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform...    49   9e-06
gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    49   9e-06
gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    49   9e-06
gi|40255245 G protein-coupled receptor 51 [Homo sapiens]               46   8e-05
gi|222080083 guanylate cyclase 2C [Homo sapiens]                       44   3e-04
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre...    44   5e-04
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr...    44   5e-04
gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]     44   5e-04
gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]     44   5e-04
gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]     44   5e-04
gi|21322252 androgen receptor isoform 1 [Homo sapiens]                 42   0.002
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]          42   0.002
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                       41   0.002
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur...    41   0.003
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso...    41   0.003
gi|122937319 even-skipped homeobox 2 [Homo sapiens]                    41   0.003
gi|8051631 RNA binding protein (autoantigenic, hnRNP-associated ...    41   0.003
gi|21396480 RNA binding protein (autoantigenic, hnRNP-associated...    41   0.003
gi|4502565 calpain, small subunit 1 [Homo sapiens]                     40   0.004
gi|51599151 calpain, small subunit 1 [Homo sapiens]                    40   0.004
gi|109452587 family with sequence similarity 98, member B isofor...    40   0.004
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa...    40   0.007
gi|140161500 ankyrin repeat and sterile alpha motif domain conta...    39   0.012
gi|119220564 one cut domain, family member 2 [Homo sapiens]            39   0.016
gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo ...    38   0.021
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]               38   0.021

>gi|4505441 natriuretic peptide receptor C/guanylate cyclase C
           (atrionatriuretic peptide receptor C) [Homo sapiens]
          Length = 540

 Score = 1087 bits (2810), Expect = 0.0
 Identities = 540/540 (100%), Positives = 540/540 (100%)

Query: 1   MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP 60
           MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP
Sbjct: 1   MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP 60

Query: 61  QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV 120
           QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV
Sbjct: 61  QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV 120

Query: 121 AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA 180
           AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA
Sbjct: 121 AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA 180

Query: 181 YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK 240
           YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK
Sbjct: 181 YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK 240

Query: 241 DLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDG 300
           DLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDG
Sbjct: 241 DLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDG 300

Query: 301 SWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEG 360
           SWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEG
Sbjct: 301 SWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEG 360

Query: 361 FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIA 420
           FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIA
Sbjct: 361 FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIA 420

Query: 421 MTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSCGLEE 480
           MTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSCGLEE
Sbjct: 421 MTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSCGLEE 480

Query: 481 SAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSVA 540
           SAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSVA
Sbjct: 481 SAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSVA 540


>gi|167830411 natriuretic peptide receptor 1 [Homo sapiens]
          Length = 1061

 Score =  217 bits (553), Expect = 2e-56
 Identities = 167/502 (33%), Positives = 249/502 (49%), Gaps = 42/502 (8%)

Query: 53  IEVLVLLP-QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNR 111
           + V V+LP  + SY +S  RV PA+E AL  V+     R  L PG   +     S+    
Sbjct: 35  LTVAVVLPLANTSYPWSWARVGPAVELALAQVKA----RPDLLPGWTVRTVLGSSE---N 87

Query: 112 ALFSLVDRVAAARGA------KPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQ 165
           AL    D  A            P + LGP C YAAAPV R  +HW +P+L+AGA A GF 
Sbjct: 88  ALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFG 147

Query: 166 HKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKL--ERNCYFTLEGVHEV 223
            KD EY+  TR  P+YAK+G+ + AL R   W R AL+    +   E +C+F +EG+   
Sbjct: 148 VKD-EYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMR 206

Query: 224 FQEEGLHTSIYSFDETKDLDLED---IVRNIQASERVVIMCASSDTIRSIMLVAHRHGMT 280
            ++  L+ ++   +  +D DL     ++R +    RV+ +C+S D  R++ML+A   G+ 
Sbjct: 207 VRDR-LNITVDHLEFAED-DLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLC 264

Query: 281 SGDYAFFNIELFNSSSYGDGS------WKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEK 334
             DY FF++++F  S  G         W+RGD  D  A+QA+ + + +T      PE+ +
Sbjct: 265 GEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLE 324

Query: 335 FSMEVKS-SVEKQGLNMED-YVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQT 392
           F  ++K  + E+    MED  VN     FHD +LLY+ A+ E L  G +  DG  I Q+ 
Sbjct: 325 FLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRM 384

Query: 393 WNRTFEGIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPW 452
           WNR+F+G+ G + ID++GDR  DFS+  M D E G   V+ +Y G           K  W
Sbjct: 385 WNRSFQGVTGYLKIDSSGDRETDFSLWDM-DPENGAFRVVLNYNGTSQELVAVSGRKLNW 443

Query: 453 GPLKLRIDENRIVEHTNSSP-CKSCGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITI 511
            PL     +       N  P C    L    V  + VG+L   G+L+  +F  +K ++  
Sbjct: 444 -PLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLAL-VGSLSLLGILIVSFFIYRKMQLEK 501

Query: 512 E--------RRTQQEESNLGKH 525
           E        R    E S+L +H
Sbjct: 502 ELASELWRVRWEDVEPSSLERH 523


>gi|4580422 natriuretic peptide receptor B precursor [Homo sapiens]
          Length = 1047

 Score =  195 bits (495), Expect = 1e-49
 Identities = 146/477 (30%), Positives = 235/477 (49%), Gaps = 35/477 (7%)

Query: 49  PP--QKIEVLVLLPQDD-SYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYED 105
           PP  + + + V+LP+ + SY ++  RV PA+  A+ ++       R LP   RF  +  +
Sbjct: 19  PPGARNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALG------RALPVDLRFVSSELE 72

Query: 106 SDCGNR-ALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGF 164
             C    A  S VD         PDL+LGP C Y AA VAR ASHW LP+L+AGA+A+GF
Sbjct: 73  GACSEYLAPLSAVDLKLYH---DPDLLLGPGCVYPAASVARFASHWRLPLLTAGAVASGF 129

Query: 165 QHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHW-SRAALVYSDDKL-ERNCYFTLEGVHE 222
             K+  Y  L R  P+  K+GE ++ L  H +W +RAAL+Y D +  +R  YFT+EGV E
Sbjct: 130 SAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFE 189

Query: 223 VFQEEGLHT--SIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMT 280
             Q   L     +Y+ +       E     I+A+ R+V +C   + +  I+L A R  +T
Sbjct: 190 ALQGSNLSVQHQVYAREPGGP---EQATHFIRANGRIVYICGPLEMLHEILLQAQRENLT 246

Query: 281 SGDYAFFNIELFNSSSYGDGS------WK--RGDKHDFEAKQAYSSLQTVTLLRTVKPEF 332
           +GDY FF +++F  S     +      W+  R  +     ++A+ ++  +T      PE+
Sbjct: 247 NGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYREPPNPEY 306

Query: 333 EKFSMEVK-SSVEKQGLNM-EDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQ 390
           ++F   +   + E  G+ +    +N+    F+D ILLY   L+E ++ G +++DG +I++
Sbjct: 307 QEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTREDGLRIVE 366

Query: 391 QTWNRTFEGIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGR--FEMRPNV 448
           +   R + G+ G V +D N DR  DF + AM D+++G  +    Y G E +  +  RP  
Sbjct: 367 KMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWWTGRP-- 424

Query: 449 KYPWGPLKLRIDENRIVEHTNSSPCKSCGLEESAVTGIVVGALLGAGLLMAFYFFRK 505
             PW       D        +   C    L   A+  +  G       + +F  FRK
Sbjct: 425 -IPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRK 480


>gi|134152694 guanylate cyclase 2F [Homo sapiens]
          Length = 1108

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 62/329 (18%), Positives = 133/329 (40%), Gaps = 22/329 (6%)

Query: 99  FQVAYEDSDCG-NRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSA 157
           F+    + DC  +RAL S +     A G      +GP         + L + WD  + S 
Sbjct: 95  FEYVILNEDCQTSRALSSFISHHQMASG-----FIGPTNPGYCEAASLLGNSWDKGIFSW 149

Query: 158 GALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTL 217
             +     +K S Y   +R  P+  ++   ++ + ++  W+ A ++ SD+ +      T 
Sbjct: 150 ACVNYELDNKIS-YPTFSRTLPSPIRV---LVTVMKYFQWAHAGVISSDEDI---WVHTA 202

Query: 218 EGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERV--VIMCASS-----DTIRSI 270
             V    +  GL   +          +   ++ I  ++R+  +IMC  S     +T   +
Sbjct: 203 NRVASALRSHGLPVGVVLTTGQDSQSMRKALQRIHQADRIRIIIMCMHSALIGGETQMHL 262

Query: 271 MLVAHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKP 330
           +  AH   MT G Y F   +    S     +  R  +++ + ++AY ++ T+T+    K 
Sbjct: 263 LECAHDLKMTDGTYVFVPYDALLYSLPYKHTPYRVLRNNPKLREAYDAVLTITVESQEKT 322

Query: 331 EFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQ 390
            ++ F+         + L   D V+      +++I     A++  ++    +     ++Q
Sbjct: 323 FYQAFTEAAARGEIPEKLEF-DQVSPLFGTIYNSIYFIAQAMNNAMKEN-GQAGAASLVQ 380

Query: 391 QTWNRTFEGIAGQVSIDANGDRYGDFSVI 419
            + N  F G    +  D+NG+   ++ ++
Sbjct: 381 HSRNMQFHGFNQLMRTDSNGNGISEYVIL 409


>gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform c
           precursor [Homo sapiens]
          Length = 899

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 82/387 (21%), Positives = 154/387 (39%), Gaps = 46/387 (11%)

Query: 73  RPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLIL 132
           +PA+E AL  V      RR + P    ++ + DS C        +  +      K  +IL
Sbjct: 127 QPAVEMALEDVNS----RRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIK--IIL 180

Query: 133 GPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALF 192
            P C   +  VA  A  W+L +LS G+ +    ++   +    R  P+        + LF
Sbjct: 181 MPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNR-QRFPTFFRTHPSATLHNPTRVKLF 239

Query: 193 RHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQ 252
               W + A +    ++  +   TL+ + E  +E G+     +F ++   D    V+N++
Sbjct: 240 EKWGWKKIATIQQTTEVFTS---TLDDLEERVKEAGIE---ITFRQSFFSDPAVPVKNLK 293

Query: 253 ASE-RVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELF--NSSSYGDGSWKRGDKHD 309
             + R+++        R +    ++  +    Y +F I  +  N     D S        
Sbjct: 294 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM 353

Query: 310 FEAKQAYSSLQTV--------TLLRTVKPEF-EKFSMEVKSSVEKQGLNMEDYVNMFVEG 360
            EA + + + + V        ++      EF EK +  +K   E+ G   E  +      
Sbjct: 354 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPL------ 407

Query: 361 FHDAILLYVLALHEVL----RAGYSKKD--------GGKIIQQTWNRTFEGIAGQVSIDA 408
            +DAI    LAL++      R+G   +D          +I +   + +FEG++G V  DA
Sbjct: 408 AYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDA 467

Query: 409 NGDRYGDFSVIAMTDVEAGTQEVIGDY 435
           +G R    +   +  ++ G+ + IG Y
Sbjct: 468 SGSR---MAWTLIEQLQGGSYKKIGYY 491


>gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform b
           precursor [Homo sapiens]
          Length = 844

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 82/387 (21%), Positives = 154/387 (39%), Gaps = 46/387 (11%)

Query: 73  RPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLIL 132
           +PA+E AL  V      RR + P    ++ + DS C        +  +      K  +IL
Sbjct: 72  QPAVEMALEDVNS----RRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIK--IIL 125

Query: 133 GPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALF 192
            P C   +  VA  A  W+L +LS G+ +    ++   +    R  P+        + LF
Sbjct: 126 MPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNR-QRFPTFFRTHPSATLHNPTRVKLF 184

Query: 193 RHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQ 252
               W + A +    ++  +   TL+ + E  +E G+     +F ++   D    V+N++
Sbjct: 185 EKWGWKKIATIQQTTEVFTS---TLDDLEERVKEAGIE---ITFRQSFFSDPAVPVKNLK 238

Query: 253 ASE-RVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELF--NSSSYGDGSWKRGDKHD 309
             + R+++        R +    ++  +    Y +F I  +  N     D S        
Sbjct: 239 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM 298

Query: 310 FEAKQAYSSLQTV--------TLLRTVKPEF-EKFSMEVKSSVEKQGLNMEDYVNMFVEG 360
            EA + + + + V        ++      EF EK +  +K   E+ G   E  +      
Sbjct: 299 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPL------ 352

Query: 361 FHDAILLYVLALHEVL----RAGYSKKD--------GGKIIQQTWNRTFEGIAGQVSIDA 408
            +DAI    LAL++      R+G   +D          +I +   + +FEG++G V  DA
Sbjct: 353 AYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDA 412

Query: 409 NGDRYGDFSVIAMTDVEAGTQEVIGDY 435
           +G R    +   +  ++ G+ + IG Y
Sbjct: 413 SGSR---MAWTLIEQLQGGSYKKIGYY 436


>gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform a
           precursor [Homo sapiens]
          Length = 961

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 82/387 (21%), Positives = 154/387 (39%), Gaps = 46/387 (11%)

Query: 73  RPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLIL 132
           +PA+E AL  V      RR + P    ++ + DS C        +  +      K  +IL
Sbjct: 189 QPAVEMALEDVNS----RRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIK--IIL 242

Query: 133 GPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALF 192
            P C   +  VA  A  W+L +LS G+ +    ++   +    R  P+        + LF
Sbjct: 243 MPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNR-QRFPTFFRTHPSATLHNPTRVKLF 301

Query: 193 RHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQ 252
               W + A +    ++  +   TL+ + E  +E G+     +F ++   D    V+N++
Sbjct: 302 EKWGWKKIATIQQTTEVFTS---TLDDLEERVKEAGIE---ITFRQSFFSDPAVPVKNLK 355

Query: 253 ASE-RVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELF--NSSSYGDGSWKRGDKHD 309
             + R+++        R +    ++  +    Y +F I  +  N     D S        
Sbjct: 356 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM 415

Query: 310 FEAKQAYSSLQTV--------TLLRTVKPEF-EKFSMEVKSSVEKQGLNMEDYVNMFVEG 360
            EA + + + + V        ++      EF EK +  +K   E+ G   E  +      
Sbjct: 416 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPL------ 469

Query: 361 FHDAILLYVLALHEVL----RAGYSKKD--------GGKIIQQTWNRTFEGIAGQVSIDA 408
            +DAI    LAL++      R+G   +D          +I +   + +FEG++G V  DA
Sbjct: 470 AYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDA 529

Query: 409 NGDRYGDFSVIAMTDVEAGTQEVIGDY 435
           +G R    +   +  ++ G+ + IG Y
Sbjct: 530 SGSR---MAWTLIEQLQGGSYKKIGYY 553


>gi|40255245 G protein-coupled receptor 51 [Homo sapiens]
          Length = 941

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 79/383 (20%), Positives = 144/383 (37%), Gaps = 36/383 (9%)

Query: 72  VRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGN-RALFSLVDRVAAARGAKPDL 130
           V PA+E A+  +      R          +   D++C N + L +  D  A   G    +
Sbjct: 77  VLPAVELAIEQIRNESLLRPYF-----LDLRLYDTECDNAKGLKAFYD--AIKYGPNHLM 129

Query: 131 ILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLA 190
           + G VC    + +A     W+L  LS  A       K  +Y +  R  P+   +   +L 
Sbjct: 130 VFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADK-KKYPYFFRTVPSDNAVNPAILK 188

Query: 191 LFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRN 250
           L +H+ W R   +  D +        L GV  ++ E+   +   SF       ++ +  N
Sbjct: 189 LLKHYQWKRVGTLTQDVQRFSEVRNDLTGV--LYGEDIEISDTESFSNDPCTSVKKLKGN 246

Query: 251 IQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGD-----GSWKRG 305
                R+++     +    +   A+   M    Y +     +  S +        S +  
Sbjct: 247 ---DVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEANSSRCL 303

Query: 306 DKHDFEAKQAY--------SSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMF 357
            K+   A + Y        SS Q  T+      ++E+     +S V     +   Y  ++
Sbjct: 304 RKNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGYAYDGIW 363

Query: 358 V--EGFHDAI-LLYVLALHEVLR-AGYSKKDGGKIIQQTWNRT-FEGIAGQVSIDANGDR 412
           V  +    A+  L+  + H+ ++   Y+    G+II    N T F G+ GQV +  NG+R
Sbjct: 364 VIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQV-VFRNGER 422

Query: 413 YGDFSVIAMTDVEAGTQEVIGDY 435
            G    I  T  +   +  +G+Y
Sbjct: 423 MG---TIKFTQFQDSREVKVGEY 442


>gi|222080083 guanylate cyclase 2C [Homo sapiens]
          Length = 1073

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 88/390 (22%), Positives = 150/390 (38%), Gaps = 54/390 (13%)

Query: 130 LILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMML 189
           +++GP C Y+   +  L +    PM+SAG+      +K++    LTR+     K+   ++
Sbjct: 118 VLIGPSCTYSTFQMY-LDTELSYPMISAGSFGLSCDYKET----LTRLMSPARKLMYFLV 172

Query: 190 AL-------FRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDL 242
                    F+ + WS  + VY +     +C++ L  + E       H   +     +D 
Sbjct: 173 NFWKTNDLPFKTYSWS-TSYVYKNGTETEDCFWYLNAL-EASVSYFSHELGFKVVLRQDK 230

Query: 243 DLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSW 302
           + +DI+ +      V+IMC   + +  +          + D     ++LFN   + D   
Sbjct: 231 EFQDILMDHNRKSNVIIMCGGPEFLYKL----KGDRAVAEDIVIILVDLFNDQYFEDN-- 284

Query: 303 KRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFH 362
                       A   ++ V +L T+ P     +  + SS  +   N+      F   + 
Sbjct: 285 ----------VTAPDYMKNVLVL-TLSPG----NSLLNSSFSR---NLSPTKRDFALAYL 326

Query: 363 DAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIAMT 422
           + ILL+   L   L  G       K      N TFEG  G V++D  GD      V+  T
Sbjct: 327 NGILLFGHMLKIFLENG-ENITTPKFAHAFRNLTFEGYDGPVTLDDWGD-VDSTMVLLYT 384

Query: 423 DVEAGTQEVIGDY---FGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSCGLE 479
            V+    +V+  Y     K    +M P   + W   KL  D       T   P +   + 
Sbjct: 385 SVDTKKYKVLLTYDTHVNKTYPVDMSPT--FTWKNSKLPND------ITGRGP-QILMIA 435

Query: 480 ESAVTGIVVGALLGAGLLMAFYFFRKKYRI 509
              +TG VV  LL A L++  Y  RK Y +
Sbjct: 436 VFTLTGAVVLLLLVALLMLRKY--RKDYEL 463


>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
           precursor [Homo sapiens]
          Length = 906

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 77/384 (20%), Positives = 144/384 (37%), Gaps = 55/384 (14%)

Query: 131 ILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLA 190
           ++GP     A  V  L   +D+P ++  A +     K + Y +  RV P+       ML 
Sbjct: 159 VIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDK-TLYKYFLRVVPSDTLQARAMLD 217

Query: 191 LFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGL----HTSIYSFDETKDLD-LE 245
           + + ++W+  + V+++     +    ++   E+  +EGL       IYS    K  D L 
Sbjct: 218 IVKRYNWTYVSAVHTEGNYGES---GMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLL 274

Query: 246 DIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFN----------IELFNSS 295
             +R      RVV+      T+R ++    R G+  G+++             IE +   
Sbjct: 275 RKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVV-GEFSLIGSDGWADRDEVIEGYEVE 333

Query: 296 SYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTV-KPEFEKFSMEVK---SSVEKQGLNM- 350
           + G  + K            +  L+  T  R    PEF +   + +     +E       
Sbjct: 334 ANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKRI 393

Query: 351 --------EDYVNMFVEGFHDAILLYVLA-----LHEVLRAGY-------SKKDGGKIIQ 390
                   E+YV     GF     +Y +A     +H  L  G+          DG K++ 
Sbjct: 394 CTGNESLEENYVQDSKMGF-VINAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGSKLLD 452

Query: 391 QTWNRTFEGIAG-QVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVK 449
                +F G++G +V  D  GD  G + ++ +   EA   + +      EG   +     
Sbjct: 453 FLIKSSFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNI----- 507

Query: 450 YPWGPLKLRIDENRIVEHTNSSPC 473
                 K++++++ +V    S PC
Sbjct: 508 ---DDYKIQMNKSGVVRSVCSEPC 528


>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
           precursor [Homo sapiens]
          Length = 1194

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 77/384 (20%), Positives = 144/384 (37%), Gaps = 55/384 (14%)

Query: 131 ILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLA 190
           ++GP     A  V  L   +D+P ++  A +     K + Y +  RV P+       ML 
Sbjct: 159 VIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDK-TLYKYFLRVVPSDTLQARAMLD 217

Query: 191 LFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGL----HTSIYSFDETKDLD-LE 245
           + + ++W+  + V+++     +    ++   E+  +EGL       IYS    K  D L 
Sbjct: 218 IVKRYNWTYVSAVHTEGNYGES---GMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLL 274

Query: 246 DIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFN----------IELFNSS 295
             +R      RVV+      T+R ++    R G+  G+++             IE +   
Sbjct: 275 RKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVV-GEFSLIGSDGWADRDEVIEGYEVE 333

Query: 296 SYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTV-KPEFEKFSMEVK---SSVEKQGLNM- 350
           + G  + K            +  L+  T  R    PEF +   + +     +E       
Sbjct: 334 ANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKRI 393

Query: 351 --------EDYVNMFVEGFHDAILLYVLA-----LHEVLRAGY-------SKKDGGKIIQ 390
                   E+YV     GF     +Y +A     +H  L  G+          DG K++ 
Sbjct: 394 CTGNESLEENYVQDSKMGF-VINAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGSKLLD 452

Query: 391 QTWNRTFEGIAG-QVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVK 449
                +F G++G +V  D  GD  G + ++ +   EA   + +      EG   +     
Sbjct: 453 FLIKSSFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNI----- 507

Query: 450 YPWGPLKLRIDENRIVEHTNSSPC 473
                 K++++++ +V    S PC
Sbjct: 508 ---DDYKIQMNKSGVVRSVCSEPC 528


>gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]
          Length = 885

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 35/153 (22%), Positives = 59/153 (38%), Gaps = 3/153 (1%)

Query: 134 PVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFR 193
           P   +   PV+  A  + +P+L      + +  K    S L R  P Y+    +   + R
Sbjct: 98  PNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFL-RTVPPYSHQSSVWFEMMR 156

Query: 194 HHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQA 253
            + W+   L+ SDD   R     LE + E  + E     +  FD         ++   + 
Sbjct: 157 VYSWNHIILLVSDDHEGRAAQKRLETLLE--ERESKAEKVLQFDPGTKNVTALLMEAKEL 214

Query: 254 SERVVIMCASSDTIRSIMLVAHRHGMTSGDYAF 286
             RV+I+ AS D   ++   A    MT   Y +
Sbjct: 215 EARVIILSASEDDAATVYRAAAMLNMTGSGYVW 247


>gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]
          Length = 938

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 35/153 (22%), Positives = 59/153 (38%), Gaps = 3/153 (1%)

Query: 134 PVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFR 193
           P   +   PV+  A  + +P+L      + +  K    S L R  P Y+    +   + R
Sbjct: 98  PNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFL-RTVPPYSHQSSVWFEMMR 156

Query: 194 HHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQA 253
            + W+   L+ SDD   R     LE + E  + E     +  FD         ++   + 
Sbjct: 157 VYSWNHIILLVSDDHEGRAAQKRLETLLE--ERESKAEKVLQFDPGTKNVTALLMEAKEL 214

Query: 254 SERVVIMCASSDTIRSIMLVAHRHGMTSGDYAF 286
             RV+I+ AS D   ++   A    MT   Y +
Sbjct: 215 EARVIILSASEDDAATVYRAAAMLNMTGSGYVW 247


>gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]
          Length = 901

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 35/153 (22%), Positives = 59/153 (38%), Gaps = 3/153 (1%)

Query: 134 PVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFR 193
           P   +   PV+  A  + +P+L      + +  K    S L R  P Y+    +   + R
Sbjct: 98  PNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFL-RTVPPYSHQSSVWFEMMR 156

Query: 194 HHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQA 253
            + W+   L+ SDD   R     LE + E  + E     +  FD         ++   + 
Sbjct: 157 VYSWNHIILLVSDDHEGRAAQKRLETLLE--ERESKAEKVLQFDPGTKNVTALLMEAKEL 214

Query: 254 SERVVIMCASSDTIRSIMLVAHRHGMTSGDYAF 286
             RV+I+ AS D   ++   A    MT   Y +
Sbjct: 215 EARVIILSASEDDAATVYRAAAMLNMTGSGYVW 247


>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
          Length = 920

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 19/29 (65%), Positives = 20/29 (68%)

Query: 22  GGTGGGGVGGGGGGAGIGGGRQEREALPP 50
           GG GGGG GGGGGG G GGG  E  A+ P
Sbjct: 452 GGGGGGGGGGGGGGGGGGGGGGEAGAVAP 480



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 16/20 (80%), Positives = 16/20 (80%)

Query: 22  GGTGGGGVGGGGGGAGIGGG 41
           GG GGGG GGGGGG G GGG
Sbjct: 451 GGGGGGGGGGGGGGGGGGGG 470



 Score = 36.2 bits (82), Expect = 0.078
 Identities = 16/22 (72%), Positives = 16/22 (72%)

Query: 20  LAGGTGGGGVGGGGGGAGIGGG 41
           L G  GGGG GGGGGG G GGG
Sbjct: 446 LYGPCGGGGGGGGGGGGGGGGG 467



 Score = 36.2 bits (82), Expect = 0.078
 Identities = 17/25 (68%), Positives = 17/25 (68%)

Query: 23  GTGGGGVGGGGGGAGIGGGRQEREA 47
           G GGGG GGGGGG G GGG    EA
Sbjct: 451 GGGGGGGGGGGGGGGGGGGGGGGEA 475



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 16/30 (53%), Positives = 16/30 (53%)

Query: 22  GGTGGGGVGGGGGGAGIGGGRQEREALPPQ 51
           GG GGGG GGGGGG   G         PPQ
Sbjct: 459 GGGGGGGGGGGGGGGEAGAVAPYGYTRPPQ 488



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 15/27 (55%), Positives = 16/27 (59%)

Query: 9   FSPCVLLGWALLAGGTGGGGVGGGGGG 35
           + PC   G     GG GGGG GGGGGG
Sbjct: 447 YGPCGGGGGGGGGGGGGGGGGGGGGGG 473


>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
          Length = 331

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 17/21 (80%), Positives = 17/21 (80%)

Query: 22 GGTGGGGVGGGGGGAGIGGGR 42
          GG GGGGVGGGG G G GGGR
Sbjct: 71 GGGGGGGVGGGGAGGGAGGGR 91



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 16/20 (80%), Positives = 17/20 (85%)

Query: 22 GGTGGGGVGGGGGGAGIGGG 41
          GG GGGG GGGGGG G+GGG
Sbjct: 62 GGGGGGGGGGGGGGGGVGGG 81



 Score = 36.2 bits (82), Expect = 0.078
 Identities = 16/23 (69%), Positives = 17/23 (73%)

Query: 18 ALLAGGTGGGGVGGGGGGAGIGG 40
          A+ A G GGGG GGGGGG G GG
Sbjct: 55 AVRAAGGGGGGGGGGGGGGGGGG 77



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 15/19 (78%), Positives = 15/19 (78%)

Query: 22 GGTGGGGVGGGGGGAGIGG 40
          GG GGGG GGGGGG G GG
Sbjct: 64 GGGGGGGGGGGGGGVGGGG 82



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 22 GGTGGGGVGGGGGGAGIGGG 41
          GG GGGG GGG GG G GGG
Sbjct: 67 GGGGGGGGGGGVGGGGAGGG 86


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 18/21 (85%), Positives = 18/21 (85%)

Query: 21 AGGTGGGGVGGGGGGAGIGGG 41
          AGG GGGG GGGGGGAG GGG
Sbjct: 29 AGGGGGGGGGGGGGGAGGGGG 49



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 16/21 (76%), Positives = 16/21 (76%)

Query: 21 AGGTGGGGVGGGGGGAGIGGG 41
          AG  GGGG GGGGGG G GGG
Sbjct: 27 AGAGGGGGGGGGGGGGGAGGG 47



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 17/26 (65%), Positives = 17/26 (65%)

Query: 22 GGTGGGGVGGGGGGAGIGGGRQEREA 47
          GG GGGG GGGGG  G GGG Q   A
Sbjct: 31 GGGGGGGGGGGGGAGGGGGGMQPGSA 56



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 15/21 (71%), Positives = 15/21 (71%)

Query: 21 AGGTGGGGVGGGGGGAGIGGG 41
          A G GGGG GGGGGG G  GG
Sbjct: 26 AAGAGGGGGGGGGGGGGGAGG 46



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 18/34 (52%), Positives = 20/34 (58%), Gaps = 6/34 (17%)

Query: 14 LLGWALLAGGT------GGGGVGGGGGGAGIGGG 41
          L G +LLA G+       G G GGGGGG G GGG
Sbjct: 10 LPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGG 43


>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
           [Homo sapiens]
          Length = 1212

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 80/410 (19%), Positives = 158/410 (38%), Gaps = 90/410 (21%)

Query: 124 RGAKPDL-ILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYA 182
           R  KP + ++GP     A  V  L   +++P ++  A +     K + + +  RV P+ A
Sbjct: 138 RSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDK-TLFKYFMRVVPSDA 196

Query: 183 KMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGL---HT-SIYS--F 236
           +    M+ + + ++W+  + V+++     +    +E   ++  +EG+   H+  IYS   
Sbjct: 197 QQARAMVDIVKRYNWTYVSAVHTEGNYGES---GMEAFKDMSAKEGICIAHSYKIYSNAG 253

Query: 237 DETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSS 296
           +++ D  L+ +  ++  +  V   C    T+R +++   R G+ +G++            
Sbjct: 254 EQSFDKLLKKLTSHLPKARVVACFCEGM-TVRGLLMAMRRLGL-AGEFLLLG-------- 303

Query: 297 YGDGSWKRGDKHDFEAKQA-------------------YSSLQTVT-------------- 323
             DG   R D  D   ++A                   Y  L+  T              
Sbjct: 304 -SDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHR 362

Query: 324 ---LLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEV---LR 377
               L     E  K++    SS+  +  +++D    FV    +AI      LH +   L 
Sbjct: 363 FQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFV---INAIYSMAYGLHNMQMSLC 419

Query: 378 AGYS-------KKDGGKIIQQTWNRTFEGIAGQ-VSIDANGDRYGDFSVIAMTDVEAGTQ 429
            GY+         DG K+++      F G++G  +  D NGD  G + ++         +
Sbjct: 420 PGYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIM-------NFK 472

Query: 430 EVIGDYF-----GKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCK 474
           E+  DYF     G     E++ +    W        ++ I+    S PC+
Sbjct: 473 EMGKDYFDYINVGSWDNGELKMDDDEVWS------KKSNIIRSVCSEPCE 516


>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
           [Homo sapiens]
          Length = 1180

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 80/410 (19%), Positives = 158/410 (38%), Gaps = 90/410 (21%)

Query: 124 RGAKPDL-ILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYA 182
           R  KP + ++GP     A  V  L   +++P ++  A +     K + + +  RV P+ A
Sbjct: 138 RSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDK-TLFKYFMRVVPSDA 196

Query: 183 KMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGL---HT-SIYS--F 236
           +    M+ + + ++W+  + V+++     +    +E   ++  +EG+   H+  IYS   
Sbjct: 197 QQARAMVDIVKRYNWTYVSAVHTEGNYGES---GMEAFKDMSAKEGICIAHSYKIYSNAG 253

Query: 237 DETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSS 296
           +++ D  L+ +  ++  +  V   C    T+R +++   R G+ +G++            
Sbjct: 254 EQSFDKLLKKLTSHLPKARVVACFCEGM-TVRGLLMAMRRLGL-AGEFLLLG-------- 303

Query: 297 YGDGSWKRGDKHDFEAKQA-------------------YSSLQTVT-------------- 323
             DG   R D  D   ++A                   Y  L+  T              
Sbjct: 304 -SDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHR 362

Query: 324 ---LLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEV---LR 377
               L     E  K++    SS+  +  +++D    FV    +AI      LH +   L 
Sbjct: 363 FQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFV---INAIYSMAYGLHNMQMSLC 419

Query: 378 AGYS-------KKDGGKIIQQTWNRTFEGIAGQ-VSIDANGDRYGDFSVIAMTDVEAGTQ 429
            GY+         DG K+++      F G++G  +  D NGD  G + ++         +
Sbjct: 420 PGYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIM-------NFK 472

Query: 430 EVIGDYF-----GKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCK 474
           E+  DYF     G     E++ +    W        ++ I+    S PC+
Sbjct: 473 EMGKDYFDYINVGSWDNGELKMDDDEVWS------KKSNIIRSVCSEPCE 516


>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
          Length = 476

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 17/20 (85%), Positives = 17/20 (85%)

Query: 22  GGTGGGGVGGGGGGAGIGGG 41
           GG GGGG GGGGGGAG GGG
Sbjct: 415 GGGGGGGGGGGGGGAGAGGG 434



 Score = 37.0 bits (84), Expect = 0.046
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 22  GGTGGGGVGGGGGGAGIGGG 41
           GG GGGG GGGGGG G G G
Sbjct: 413 GGGGGGGGGGGGGGGGAGAG 432



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 16/24 (66%), Positives = 17/24 (70%)

Query: 18  ALLAGGTGGGGVGGGGGGAGIGGG 41
           A  A G+ GGG GGGGGG G GGG
Sbjct: 405 AAAALGSRGGGGGGGGGGGGGGGG 428



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 15/24 (62%), Positives = 15/24 (62%)

Query: 18  ALLAGGTGGGGVGGGGGGAGIGGG 41
           A L    GGGG GGGGGG G G G
Sbjct: 407 AALGSRGGGGGGGGGGGGGGGGAG 430



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 14/24 (58%), Positives = 14/24 (58%)

Query: 18  ALLAGGTGGGGVGGGGGGAGIGGG 41
           A  A   G  G GGGGGG G GGG
Sbjct: 403 AAAAAALGSRGGGGGGGGGGGGGG 426


>gi|8051631 RNA binding protein (autoantigenic, hnRNP-associated
           with lethal yellow) long isoform [Homo sapiens]
          Length = 306

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 20/44 (45%), Positives = 23/44 (52%)

Query: 21  AGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLPQDDS 64
           AGG GGGG  GGGG  G GGG   R   P +       LPQ ++
Sbjct: 230 AGGGGGGGGSGGGGSGGGGGGGSSRPPAPQENTTSEAGLPQGEA 273



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 17/29 (58%), Positives = 18/29 (62%)

Query: 22  GGTGGGGVGGGGGGAGIGGGRQEREALPP 50
           GG GGGG GGG GG G GGG     + PP
Sbjct: 228 GGAGGGGGGGGSGGGGSGGGGGGGSSRPP 256



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 13/16 (81%), Positives = 13/16 (81%)

Query: 26  GGGVGGGGGGAGIGGG 41
           GGG GGGGGG G GGG
Sbjct: 227 GGGAGGGGGGGGSGGG 242


>gi|21396480 RNA binding protein (autoantigenic, hnRNP-associated
           with lethal yellow) short isoform [Homo sapiens]
          Length = 290

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 20/44 (45%), Positives = 23/44 (52%)

Query: 21  AGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLPQDDS 64
           AGG GGGG  GGGG  G GGG   R   P +       LPQ ++
Sbjct: 214 AGGGGGGGGSGGGGSGGGGGGGSSRPPAPQENTTSEAGLPQGEA 257



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 17/29 (58%), Positives = 18/29 (62%)

Query: 22  GGTGGGGVGGGGGGAGIGGGRQEREALPP 50
           GG GGGG GGG GG G GGG     + PP
Sbjct: 212 GGAGGGGGGGGSGGGGSGGGGGGGSSRPP 240



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 13/16 (81%), Positives = 13/16 (81%)

Query: 26  GGGVGGGGGGAGIGGG 41
           GGG GGGGGG G GGG
Sbjct: 211 GGGAGGGGGGGGSGGG 226


>gi|4502565 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 21/33 (63%), Positives = 21/33 (63%)

Query: 13 VLLGWALLAGGTGGGGVGGGGGGAGIGGGRQER 45
          VL G    AGG GGGG GGGGGG G GGG   R
Sbjct: 28 VLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 12/15 (80%), Positives = 13/15 (86%)

Query: 27 GGVGGGGGGAGIGGG 41
          GG GGGGGG G+GGG
Sbjct: 10 GGGGGGGGGGGLGGG 24



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 14/26 (53%), Positives = 15/26 (57%)

Query: 16 GWALLAGGTGGGGVGGGGGGAGIGGG 41
          G   + GG   G  GGGGGG G GGG
Sbjct: 24 GLGNVLGGLISGAGGGGGGGGGGGGG 49



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 14/22 (63%), Positives = 16/22 (72%), Gaps = 1/22 (4%)

Query: 18 ALLAGGTGGGGVGGGGGGAGIG 39
          + L GG GGGG GGGG G G+G
Sbjct: 6  SFLKGGGGGGG-GGGGLGGGLG 26



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 13/17 (76%), Positives = 13/17 (76%)

Query: 25 GGGGVGGGGGGAGIGGG 41
          GGGG GGGGGG G G G
Sbjct: 10 GGGGGGGGGGGLGGGLG 26



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 16/28 (57%), Positives = 17/28 (60%), Gaps = 8/28 (28%)

Query: 22 GGTGGGGVGGGGG--------GAGIGGG 41
          GG GGGG+GGG G        GAG GGG
Sbjct: 14 GGGGGGGLGGGLGNVLGGLISGAGGGGG 41



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 15/24 (62%), Positives = 16/24 (66%), Gaps = 2/24 (8%)

Query: 19 LLAGGTGGGGVGGGGGGAG--IGG 40
          L  GG GGGG GG GGG G  +GG
Sbjct: 8  LKGGGGGGGGGGGLGGGLGNVLGG 31


>gi|51599151 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 21/33 (63%), Positives = 21/33 (63%)

Query: 13 VLLGWALLAGGTGGGGVGGGGGGAGIGGGRQER 45
          VL G    AGG GGGG GGGGGG G GGG   R
Sbjct: 28 VLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 12/15 (80%), Positives = 13/15 (86%)

Query: 27 GGVGGGGGGAGIGGG 41
          GG GGGGGG G+GGG
Sbjct: 10 GGGGGGGGGGGLGGG 24



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 14/26 (53%), Positives = 15/26 (57%)

Query: 16 GWALLAGGTGGGGVGGGGGGAGIGGG 41
          G   + GG   G  GGGGGG G GGG
Sbjct: 24 GLGNVLGGLISGAGGGGGGGGGGGGG 49



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 14/22 (63%), Positives = 16/22 (72%), Gaps = 1/22 (4%)

Query: 18 ALLAGGTGGGGVGGGGGGAGIG 39
          + L GG GGGG GGGG G G+G
Sbjct: 6  SFLKGGGGGGG-GGGGLGGGLG 26



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 13/17 (76%), Positives = 13/17 (76%)

Query: 25 GGGGVGGGGGGAGIGGG 41
          GGGG GGGGGG G G G
Sbjct: 10 GGGGGGGGGGGLGGGLG 26



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 16/28 (57%), Positives = 17/28 (60%), Gaps = 8/28 (28%)

Query: 22 GGTGGGGVGGGGG--------GAGIGGG 41
          GG GGGG+GGG G        GAG GGG
Sbjct: 14 GGGGGGGLGGGLGNVLGGLISGAGGGGG 41



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 15/24 (62%), Positives = 16/24 (66%), Gaps = 2/24 (8%)

Query: 19 LLAGGTGGGGVGGGGGGAG--IGG 40
          L  GG GGGG GG GGG G  +GG
Sbjct: 8  LKGGGGGGGGGGGLGGGLGNVLGG 31


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 18/27 (66%), Positives = 18/27 (66%)

Query: 16  GWALLAGGTGGGGVGGGGGGAGIGGGR 42
           GW    GG GGGG GGGG G G GGGR
Sbjct: 358 GWGGGGGGWGGGGGGGGGWGGGGGGGR 384



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 17/25 (68%), Positives = 17/25 (68%), Gaps = 3/25 (12%)

Query: 16  GWALLAGGTGGGGVGGGGGGAGIGG 40
           GW    GG GGGG GGGGGG G GG
Sbjct: 337 GWG---GGGGGGGRGGGGGGGGRGG 358



 Score = 37.0 bits (84), Expect = 0.046
 Identities = 16/21 (76%), Positives = 16/21 (76%)

Query: 22  GGTGGGGVGGGGGGAGIGGGR 42
           GG GGGG GGG GG G GGGR
Sbjct: 336 GGWGGGGGGGGRGGGGGGGGR 356



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 22  GGTGGGGVGGGGGGAGIGGG 41
           GG G GG GGGGGG G GGG
Sbjct: 331 GGGGRGGWGGGGGGGGRGGG 350



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 22  GGTGGGGVGGGGGGAGIGGG 41
           GG GG G GGGGGG G GGG
Sbjct: 333 GGRGGWGGGGGGGGRGGGGG 352



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 18/30 (60%), Positives = 18/30 (60%), Gaps = 4/30 (13%)

Query: 16  GWALLAGGTGGGGVGGGGGGAGIGGGRQER 45
           GW    GG GGGG G GGGG G  GG Q R
Sbjct: 365 GW----GGGGGGGGGWGGGGGGGRGGFQGR 390



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 22  GGTGGGGVGGGGGGAGIGGG 41
           GG GGGG GGG GG G GGG
Sbjct: 345 GGRGGGGGGGGRGGWGGGGG 364



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 16/21 (76%), Positives = 16/21 (76%), Gaps = 1/21 (4%)

Query: 22  GGTGGGGVGG-GGGGAGIGGG 41
           GG GGGG GG GGGG G GGG
Sbjct: 349 GGGGGGGRGGWGGGGGGWGGG 369



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 22  GGTGGGGVGGGGGGAGIGGG 41
           GG G GG GGGGGG G GGG
Sbjct: 352 GGGGRGGWGGGGGGWGGGGG 371



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 16/23 (69%), Positives = 16/23 (69%), Gaps = 3/23 (13%)

Query: 22  GGTGGGGVG---GGGGGAGIGGG 41
           GG GGGG G   GGGGG G GGG
Sbjct: 357 GGWGGGGGGWGGGGGGGGGWGGG 379



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 14/20 (70%), Positives = 14/20 (70%)

Query: 22  GGTGGGGVGGGGGGAGIGGG 41
           GG GG G GGGG G G GGG
Sbjct: 354 GGRGGWGGGGGGWGGGGGGG 373



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 14/22 (63%), Positives = 15/22 (68%)

Query: 22  GGTGGGGVGGGGGGAGIGGGRQ 43
           G   GGG GGGGGG G GG R+
Sbjct: 411 GDPYGGGGGGGGGGGGGGGYRR 432



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 15/23 (65%), Positives = 15/23 (65%), Gaps = 3/23 (13%)

Query: 22  GGTGGGGVG---GGGGGAGIGGG 41
           GG GG G G   GGGGG G GGG
Sbjct: 403 GGYGGRGYGDPYGGGGGGGGGGG 425



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 16/27 (59%), Positives = 16/27 (59%), Gaps = 3/27 (11%)

Query: 22  GGTGGG---GVGGGGGGAGIGGGRQER 45
           GG G G   G GGGGGG G GGG   R
Sbjct: 406 GGRGYGDPYGGGGGGGGGGGGGGGYRR 432


>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
          sapiens]
          Length = 443

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 18/24 (75%), Positives = 18/24 (75%)

Query: 18 ALLAGGTGGGGVGGGGGGAGIGGG 41
          AL  GG GGGG GGGGGG G GGG
Sbjct: 64 ALSHGGGGGGGGGGGGGGGGGGGG 87



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 16/20 (80%), Positives = 16/20 (80%)

Query: 22 GGTGGGGVGGGGGGAGIGGG 41
          GG GGGG GGGGGG G GGG
Sbjct: 69 GGGGGGGGGGGGGGGGGGGG 88



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 15/25 (60%), Positives = 15/25 (60%)

Query: 17 WALLAGGTGGGGVGGGGGGAGIGGG 41
          W       GGGG GGGGGG G GGG
Sbjct: 61 WITALSHGGGGGGGGGGGGGGGGGG 85



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 22 GGTGGGGVGGGGGGAGIGGG 41
          GG GGGG GGGGGG G G G
Sbjct: 71 GGGGGGGGGGGGGGGGGGDG 90



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 18/40 (45%), Positives = 21/40 (52%)

Query: 22  GGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLPQ 61
           GG GGGG GGGGGG G  G       L    I+  V++ Q
Sbjct: 72  GGGGGGGGGGGGGGGGGDGSPWSTSPLGQPDIKPSVVVQQ 111


>gi|140161500 ankyrin repeat and sterile alpha motif domain
          containing 1 [Homo sapiens]
          Length = 1134

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 16/20 (80%), Positives = 17/20 (85%)

Query: 22 GGTGGGGVGGGGGGAGIGGG 41
          GG GGGG GGGGGG+G GGG
Sbjct: 33 GGGGGGGSGGGGGGSGGGGG 52



 Score = 36.2 bits (82), Expect = 0.078
 Identities = 17/29 (58%), Positives = 19/29 (65%)

Query: 13 VLLGWALLAGGTGGGGVGGGGGGAGIGGG 41
          +L G  L +G  GGGG G GGGG G GGG
Sbjct: 22 LLSGKRLSSGFGGGGGGGSGGGGGGSGGG 50



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 14/27 (51%), Positives = 17/27 (62%)

Query: 22 GGTGGGGVGGGGGGAGIGGGRQEREAL 48
          GG+GGGG G GGGG G+G       +L
Sbjct: 38 GGSGGGGGGSGGGGGGLGSSSHPLSSL 64



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 14/20 (70%), Positives = 14/20 (70%)

Query: 22 GGTGGGGVGGGGGGAGIGGG 41
          GG GGG  GGGGG  G GGG
Sbjct: 34 GGGGGGSGGGGGGSGGGGGG 53



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 13/20 (65%), Positives = 13/20 (65%)

Query: 22 GGTGGGGVGGGGGGAGIGGG 41
          GG G GG GGG GG G G G
Sbjct: 36 GGGGSGGGGGGSGGGGGGLG 55


>gi|119220564 one cut domain, family member 2 [Homo sapiens]
          Length = 504

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 18/28 (64%), Positives = 19/28 (67%)

Query: 22 GGTGGGGVGGGGGGAGIGGGRQEREALP 49
          GG+GGGG GGGGGG G  G  QE  A P
Sbjct: 38 GGSGGGGGGGGGGGGGGPGHEQELLASP 65



 Score = 36.2 bits (82), Expect = 0.078
 Identities = 16/30 (53%), Positives = 18/30 (60%)

Query: 21 AGGTGGGGVGGGGGGAGIGGGRQEREALPP 50
          AGG  GGG GGGGGG G G G ++     P
Sbjct: 36 AGGGSGGGGGGGGGGGGGGPGHEQELLASP 65



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 15/22 (68%), Positives = 15/22 (68%)

Query: 20 LAGGTGGGGVGGGGGGAGIGGG 41
          L G  GGG  GGGGGG G GGG
Sbjct: 32 LHGPAGGGSGGGGGGGGGGGGG 53


>gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo
           sapiens]
          Length = 3258

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 18/33 (54%), Positives = 20/33 (60%)

Query: 22  GGTGGGGVGGGGGGAGIGGGRQEREALPPQKIE 54
           GG GGGG G GGGG G GGG  E+     +K E
Sbjct: 747 GGDGGGGGGDGGGGGGGGGGPYEKNDKNQEKDE 779



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 22  GGTGGGGVGGGGGGAGIGGG 41
           G  GGGG GGGGGG G GGG
Sbjct: 742 GEEGGGGDGGGGGGDGGGGG 761



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 14/20 (70%), Positives = 14/20 (70%)

Query: 22  GGTGGGGVGGGGGGAGIGGG 41
           GG G GG GGG GG G GGG
Sbjct: 745 GGGGDGGGGGGDGGGGGGGG 764



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 16/31 (51%), Positives = 17/31 (54%)

Query: 10  SPCVLLGWALLAGGTGGGGVGGGGGGAGIGG 40
           S C   G A+   G GGG  GGGG G G GG
Sbjct: 725 STCGFGGPAVSGAGDGGGEEGGGGDGGGGGG 755



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 14/29 (48%), Positives = 16/29 (55%)

Query: 22  GGTGGGGVGGGGGGAGIGGGRQEREALPP 50
           GG GGGG GGGGG        QE++   P
Sbjct: 754 GGDGGGGGGGGGGPYEKNDKNQEKDESTP 782



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 13/20 (65%), Positives = 13/20 (65%)

Query: 22  GGTGGGGVGGGGGGAGIGGG 41
           GG  GGG  GGGGG   GGG
Sbjct: 741 GGEEGGGGDGGGGGGDGGGG 760


>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
          Length = 332

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 16/37 (43%), Positives = 21/37 (56%)

Query: 22 GGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVL 58
          GG+GGG   GGGG  G GGG       PP+++ +  L
Sbjct: 46 GGSGGGNGAGGGGAGGAGGGGGGGSRAPPEELSMFQL 82



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 16/24 (66%), Positives = 16/24 (66%), Gaps = 1/24 (4%)

Query: 19 LLAGGTGGGGVGGGGG-GAGIGGG 41
          LLA   GG G GGGGG G G GGG
Sbjct: 28 LLASSGGGNGAGGGGGAGGGSGGG 51



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 13/20 (65%), Positives = 14/20 (70%)

Query: 22 GGTGGGGVGGGGGGAGIGGG 41
          GG G GG GG GGG+G G G
Sbjct: 34 GGNGAGGGGGAGGGSGGGNG 53



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 22 GGTGGGGVG-GGGGGAGIGGGRQEREALPPQKIEVLVLLPQ 61
          GG G GG G GG GG G GG R   E L   ++  L   P+
Sbjct: 50 GGNGAGGGGAGGAGGGGGGGSRAPPEELSMFQLPTLNFSPE 90



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 15/21 (71%), Positives = 15/21 (71%), Gaps = 1/21 (4%)

Query: 21 AGGTGGGGVGGGGGGAGIGGG 41
          AGG GG G GG GGG G GGG
Sbjct: 38 AGGGGGAG-GGSGGGNGAGGG 57



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 13/24 (54%), Positives = 16/24 (66%)

Query: 18 ALLAGGTGGGGVGGGGGGAGIGGG 41
          ++L   +GGG   GGGGGAG G G
Sbjct: 26 SILLASSGGGNGAGGGGGAGGGSG 49


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,345,439
Number of Sequences: 37866
Number of extensions: 954446
Number of successful extensions: 12461
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 215
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 6917
Number of HSP's gapped (non-prelim): 3285
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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