Guide to the Human Genome
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Search of human proteins with 4505331

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505331 N-ethylmaleimide-sensitive factor attachment
protein, gamma [Homo sapiens]
         (312 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505331 N-ethylmaleimide-sensitive factor attachment protein,...   622   e-178
gi|44917606 N-ethylmaleimide-sensitive factor attachment protein...    64   2e-10
gi|47933379 N-ethylmaleimide-sensitive factor attachment protein...    60   2e-09
gi|34304360 nephrocystin 3 [Homo sapiens]                              37   0.023
gi|38488692 SH3 domain and tetratricopeptide repeats 2 [Homo sap...    35   0.066
gi|73747889 a disintegrin and metalloprotease domain 17 prepropr...    33   0.25 
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H...    33   0.42 
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H...    33   0.42 
gi|51317366 myosin XVIIIB [Homo sapiens]                               33   0.42 
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi...    32   0.55 
gi|197333695 poly(A)-specific ribonuclease (deadenylation nuclea...    32   0.55 
gi|4505611 poly(A)-specific ribonuclease (deadenylation nuclease...    32   0.55 
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            31   1.2  
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho...    31   1.2  
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho...    31   1.2  
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi...    31   1.2  
gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...    31   1.2  
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     30   2.1  
gi|88196790 coiled-coil domain containing 88 [Homo sapiens]            30   2.1  
gi|45439327 periplakin [Homo sapiens]                                  30   2.1  
gi|12056463 coagulation factor VIII-associated protein [Homo sap...    30   2.8  
gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo sap...    30   2.8  
gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sap...    30   2.8  
gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo sap...    30   2.8  
gi|56090586 coagulation factor VIII-associated (intronic transcr...    30   2.8  
gi|56090588 coagulation factor VIII-associated (intronic transcr...    30   2.8  
gi|32261320 PSMC3 interacting protein isoform 1 [Homo sapiens]         30   3.6  
gi|55743151 WD repeat domain 19 [Homo sapiens]                         30   3.6  
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]         29   4.7  
gi|41872403 flavin adenine dinucleotide synthetase isoform 2 [Ho...    29   4.7  

>gi|4505331 N-ethylmaleimide-sensitive factor attachment protein,
           gamma [Homo sapiens]
          Length = 312

 Score =  622 bits (1604), Expect = e-178
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 1   MAAQKINEGLEHLAKAEKYLKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLR 60
           MAAQKINEGLEHLAKAEKYLKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLR
Sbjct: 1   MAAQKINEGLEHLAKAEKYLKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLR 60

Query: 61  EAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALER 120
           EAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALER
Sbjct: 61  EAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALER 120

Query: 121 AGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQKE 180
           AGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQKE
Sbjct: 121 AGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQKE 180

Query: 181 KNIYKEIENYPTCYKKTIAQVLVHLHRNDYVAAERCVRESYSIPGFNGSEDCAALEQLLE 240
           KNIYKEIENYPTCYKKTIAQVLVHLHRNDYVAAERCVRESYSIPGFNGSEDCAALEQLLE
Sbjct: 181 KNIYKEIENYPTCYKKTIAQVLVHLHRNDYVAAERCVRESYSIPGFNGSEDCAALEQLLE 240

Query: 241 GYDQQDQDQVSDVCNSPLFKYMDNDYAKLGLSLVVPGGGIKKKSPATPQAKPDGVTATAA 300
           GYDQQDQDQVSDVCNSPLFKYMDNDYAKLGLSLVVPGGGIKKKSPATPQAKPDGVTATAA
Sbjct: 241 GYDQQDQDQVSDVCNSPLFKYMDNDYAKLGLSLVVPGGGIKKKSPATPQAKPDGVTATAA 300

Query: 301 DEEEDEYSGGLC 312
           DEEEDEYSGGLC
Sbjct: 301 DEEEDEYSGGLC 312


>gi|44917606 N-ethylmaleimide-sensitive factor attachment protein,
           beta [Homo sapiens]
          Length = 298

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 71/272 (26%), Positives = 114/272 (41%), Gaps = 36/272 (13%)

Query: 3   AQKINEGLEHLAKAEKYLKT------GFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKD 56
           A K  E ++ +A+AEK +K       G        + A   Y +AA  FK AK +  A +
Sbjct: 4   AGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSAAGN 63

Query: 57  ACLREAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAM 116
           A  + A  H   ++   +A ++  AG   K+     EA+  +  A  +Y + G    AA 
Sbjct: 64  AFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADP-QEAINCLNAAIDIYTDMGRFTIAAK 122

Query: 117 ALERAGKLIEN--VDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAA 174
                 ++ E   VD EKA+  Y+Q+A+ ++ EE    A + L K             AA
Sbjct: 123 HHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKV------------AA 170

Query: 175 LSIQKEKNIYKEIENYPTCYKKTIAQVLVHLHRNDY-VAAERC-----------VRESYS 222
            + Q E+   K IE Y      T+   L+     DY   A  C             E Y 
Sbjct: 171 YAAQLEQ-YQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYE 229

Query: 223 --IPGFNGSEDCAALEQLLEGYDQQDQDQVSD 252
              P F  S +C  L++LLE +++Q+ +  ++
Sbjct: 230 EMFPAFTDSRECKLLKKLLEAHEEQNSEAYTE 261


>gi|47933379 N-ethylmaleimide-sensitive factor attachment protein,
           alpha [Homo sapiens]
          Length = 295

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 61/266 (22%), Positives = 116/266 (43%), Gaps = 34/266 (12%)

Query: 8   EGLEHLAKAEKYLK------TGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLRE 61
           E +  LA+AE+ +K      +G        + A   Y +AA  FK AK +  A +A  + 
Sbjct: 9   EAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSAAGNAFCQA 68

Query: 62  AVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALERA 121
           A  H   ++   AA  +  AG   K+     EA+  + +A  +Y + G    AA      
Sbjct: 69  AQLHLQLQSKHDAATCFVDAGNAFKKADP-QEAINCLMRAIEIYTDMGRFTIAAKHHISI 127

Query: 122 GKLIEN--VDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQK 179
            ++ E   VD EKA+  Y+Q+A+ ++ EE           A++ L++   +       QK
Sbjct: 128 AEIYETELVDIEKAIAHYEQSADYYKGEESN-------SSANKCLLKVAGYAALLEQYQK 180

Query: 180 EKNIYKEIENYPT------------CYKKTIAQVLVHLHRNDYVAAERCVRESYSI-PGF 226
             +IY+++                  +K  +    +     D + A+  V++   + P F
Sbjct: 181 AIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCI-----DMLNAKLAVQKYEELFPAF 235

Query: 227 NGSEDCAALEQLLEGYDQQDQDQVSD 252
           + S +C  +++LLE +++Q+ D  ++
Sbjct: 236 SDSRECKLMKKLLEAHEEQNVDSYTE 261


>gi|34304360 nephrocystin 3 [Homo sapiens]
          Length = 1330

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 8/167 (4%)

Query: 29   PDYDSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFHAAKAY--EQAGMMLK 86
            PD+   A      A      KQ+++A++   R         A  H + AY  +   ++ K
Sbjct: 1129 PDHPDCAQSLNNLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYK 1188

Query: 87   EMQKLPEAVQLIEKASMMYLENGTP--DTAAMALERAGKLIENVDPE-KAVQLYQQTANV 143
            +M KL +AV L E A  +  ++  P   + A AL     L   +    +A+ LY++   +
Sbjct: 1189 KMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKI 1248

Query: 144  FENE-ERLRQAV-ELLGKASRLLVRGRRFDEAALSIQKEKNIYKEIE 188
            +E+   R+   V E L   + L   G  F++AA  + K     KE E
Sbjct: 1249 YEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAA-ELYKRAMEIKEAE 1294



 Score = 32.3 bits (72), Expect = 0.55
 Identities = 31/132 (23%), Positives = 55/132 (41%), Gaps = 15/132 (11%)

Query: 29   PDYDSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFH--AAKAYEQAGMMLK 86
            PD+ S A      A+ +K   + ++A           + +    H   A A     ++  
Sbjct: 1171 PDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYS 1230

Query: 87   EMQKLPEAVQLIEKASMMYLENGTPDTAAMALERAGKLIENV--------DPEKAVQLYQ 138
            +M+K  EA+ L E+A  +Y      D+      R G+ ++N+        D EKA +LY+
Sbjct: 1231 QMKKHVEALPLYERALKIY-----EDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYK 1285

Query: 139  QTANVFENEERL 150
            +   + E E  L
Sbjct: 1286 RAMEIKEAETSL 1297


>gi|38488692 SH3 domain and tetratricopeptide repeats 2 [Homo sapiens]
          Length = 1288

 Score = 35.4 bits (80), Expect = 0.066
 Identities = 50/214 (23%), Positives = 88/214 (41%), Gaps = 40/214 (18%)

Query: 56   DACLREAVAHENNRALFHAAKAYEQAGMMLKEM----------QKLPEAVQLIEKASMMY 105
            +AC+     HE+  AL    +  E  G +L+ +          + L  ++  I+++  ++
Sbjct: 978  EACI---TYHEHWLALAQQLRDREMEGRLLESLGQLYRNLNTARSLRRSLTCIKESLRIF 1034

Query: 106  LENGTPDTAAMALERAGKL---------------------IENVDPEKAVQLYQQTANVF 144
            ++ G  D AA A   AG+L                     +++ +P  A++LY++  +VF
Sbjct: 1035 IDLGETDKAAEAWLGAGRLHYLMQEDELVELCLQAAIQTALKSEEPLLALKLYEEAGDVF 1094

Query: 145  ENEERLR-QAVELLGKASRLLVRGRRFDEAALSI-QKEKNIYKEIENYPTCYK-KTIAQV 201
             N  R R  AVE     +  L R  +     L I  K   +   +E Y    +  T+A  
Sbjct: 1095 FNGTRHRHHAVEYYRAGAVPLARRLKAVRTELRIFNKLTELQISLEGYEKALEFATLAAR 1154

Query: 202  LVHL---HRNDYVAAERCVRESYSIPGFNGSEDC 232
            L  +    R + VA  R     YS+  +  +EDC
Sbjct: 1155 LSTVTGDQRQELVAFHRLATVYYSLHMYEMAEDC 1188


>gi|73747889 a disintegrin and metalloprotease domain 17
           preproprotein [Homo sapiens]
          Length = 824

 Score = 33.5 bits (75), Expect = 0.25
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 10/82 (12%)

Query: 227 NGSEDCAALEQLLEGYDQQDQDQVSDVCNSPLFKYMDNDYAKLGLSLV-----VPGGGIK 281
           N  +D   ++ LLE +     ++ S VC + LF Y D D   LGL+ V        GG+ 
Sbjct: 306 NEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVC 365

Query: 282 KKSPATPQAKPD-----GVTAT 298
            K+  +P  K +     G+T+T
Sbjct: 366 PKAYYSPVGKKNIYLNSGLTST 387


>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
           sapiens]
          Length = 506

 Score = 32.7 bits (73), Expect = 0.42
 Identities = 41/160 (25%), Positives = 64/160 (40%), Gaps = 19/160 (11%)

Query: 34  AASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFHA--AKAYEQAGMMLKEMQKL 91
           A SE  +    FK  K +E+A + C    +A +   AL  A  A AY +     +  +  
Sbjct: 123 AISEKDRGNGFFKEGK-YERAIE-CYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180

Query: 92  PEAVQLIEKASMMYLENGTPDTAAMALERAGKLIENVDPEKAVQLYQQTANVFENEERLR 151
            +A+ L    S  +   GT  T    L  A +  E V       L  +  N        +
Sbjct: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETV-------LLLEPGN--------K 225

Query: 152 QAVELLGKASRLLVRGRRFDEAALSIQKEKNIYKEIENYP 191
           QAV  L K  + L+    +D+  L   + +N+ K I+N P
Sbjct: 226 QAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPIDNPP 265


>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
           sapiens]
          Length = 665

 Score = 32.7 bits (73), Expect = 0.42
 Identities = 41/160 (25%), Positives = 64/160 (40%), Gaps = 19/160 (11%)

Query: 34  AASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFHA--AKAYEQAGMMLKEMQKL 91
           A SE  +    FK  K +E+A + C    +A +   AL  A  A AY +     +  +  
Sbjct: 282 AISEKDRGNGFFKEGK-YERAIE-CYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 339

Query: 92  PEAVQLIEKASMMYLENGTPDTAAMALERAGKLIENVDPEKAVQLYQQTANVFENEERLR 151
            +A+ L    S  +   GT  T    L  A +  E V       L  +  N        +
Sbjct: 340 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETV-------LLLEPGN--------K 384

Query: 152 QAVELLGKASRLLVRGRRFDEAALSIQKEKNIYKEIENYP 191
           QAV  L K  + L+    +D+  L   + +N+ K I+N P
Sbjct: 385 QAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPIDNPP 424


>gi|51317366 myosin XVIIIB [Homo sapiens]
          Length = 2567

 Score = 32.7 bits (73), Expect = 0.42
 Identities = 36/173 (20%), Positives = 75/173 (43%), Gaps = 16/173 (9%)

Query: 59   LREAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIE--KASMMYLENGTPDTAAM 116
            LRE V  EN    +   +  +Q     +E  +L + V++++  K  ++   +   +  A 
Sbjct: 1626 LREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAG 1685

Query: 117  ALERAGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALS 176
              ER  KL  +   ++ +Q  Q+  N  +  E+LRQ  EL  +  + + +  R D+    
Sbjct: 1686 LKERLWKLESSALEQQKIQSQQE--NTIKQLEQLRQRFELEIERMKQMHQKDREDQE--- 1740

Query: 177  IQKEKNIYKEIENYPTCYKKTIAQVLVHLHRNDYVAAERCVRESYSIPGFNGS 229
                    +E+E+     +K + Q+ + L + +Y   +  + E   + G  G+
Sbjct: 1741 --------EELEDVRQSCQKRLHQLEMQLEQ-EYEEKQMVLHEKQDLEGLIGT 1784


>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
           protein) [Homo sapiens]
          Length = 543

 Score = 32.3 bits (72), Expect = 0.55
 Identities = 41/197 (20%), Positives = 69/197 (35%), Gaps = 52/197 (26%)

Query: 28  KPDYDSAASEYGKA--------------AVAFKNAKQFEQAKDACLREA-VAHENNRALF 72
           K D+D+A   Y KA              A  +     + + ++ C +   V  EN     
Sbjct: 238 KKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYR 297

Query: 73  HAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALERAGKLIENVDPEK 132
             AKAY + G    + +K  +A+    K+     E+ TPD                    
Sbjct: 298 QIAKAYARIGNSYFKEEKYKDAIHFYNKS---LAEHRTPD-------------------- 334

Query: 133 AVQLYQQTANVFENEERLRQ-----AVELLGKASRLLVRG------RRFDEAALSIQKEK 181
            ++  QQ   + + +ERL       A+E   K +    +G      + + EA     K+ 
Sbjct: 335 VLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDA 394

Query: 182 NIYKEIENYPTCYKKTI 198
            +Y    N   CY K +
Sbjct: 395 KLY---SNRAACYTKLL 408


>gi|197333695 poly(A)-specific ribonuclease (deadenylation nuclease)
           isoform 2 [Homo sapiens]
          Length = 578

 Score = 32.3 bits (72), Expect = 0.55
 Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 11/131 (8%)

Query: 167 GRRFDEAALSIQKEKNIYKEIENY---PTCYKKTIAQVLVHLHRNDYVAAERCVRESYSI 223
           GR+ +E  +  +  ++ +KE ++    P C   T+     H +RN+   A   V +    
Sbjct: 453 GRKQEEKQIKRKWTEDSWKEADSKRLNPQCIPYTLQN---HYYRNNSFTAPSTVGKRNLS 509

Query: 224 PGFNGSEDCAALEQLLEGYDQQDQDQVSDVCNSPLFKYMDN-DYAKLGLSLVVPGGGIKK 282
           P    S++ A LE  + G     + + +D C  PL +        K     + P G I K
Sbjct: 510 P----SQEEAGLEDGVSGEISDTELEQTDSCAEPLSEGRKKAKKLKRMKKELSPAGSISK 565

Query: 283 KSPATPQAKPD 293
            SPAT    PD
Sbjct: 566 NSPATLFEVPD 576


>gi|4505611 poly(A)-specific ribonuclease (deadenylation nuclease)
           isoform 1 [Homo sapiens]
          Length = 639

 Score = 32.3 bits (72), Expect = 0.55
 Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 11/131 (8%)

Query: 167 GRRFDEAALSIQKEKNIYKEIENY---PTCYKKTIAQVLVHLHRNDYVAAERCVRESYSI 223
           GR+ +E  +  +  ++ +KE ++    P C   T+     H +RN+   A   V +    
Sbjct: 514 GRKQEEKQIKRKWTEDSWKEADSKRLNPQCIPYTLQN---HYYRNNSFTAPSTVGKRNLS 570

Query: 224 PGFNGSEDCAALEQLLEGYDQQDQDQVSDVCNSPLFKYMDN-DYAKLGLSLVVPGGGIKK 282
           P    S++ A LE  + G     + + +D C  PL +        K     + P G I K
Sbjct: 571 P----SQEEAGLEDGVSGEISDTELEQTDSCAEPLSEGRKKAKKLKRMKKELSPAGSISK 626

Query: 283 KSPATPQAKPD 293
            SPAT    PD
Sbjct: 627 NSPATLFEVPD 637


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 5/111 (4%)

Query: 52  EQAKDACLREAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTP 111
           EQ +  C +E    E    L    +   +    L E +KLP   +L+E+   +  +    
Sbjct: 294 EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQ 353

Query: 112 DTAAMALERAGKLIENVDPEKAVQLYQQTANVFENE-----ERLRQAVELL 157
           +     LER   L E  +  +  +L QQ   +++ E     ERLR+   +L
Sbjct: 354 EEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERML 404


>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
           sapiens]
          Length = 725

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 30/127 (23%), Positives = 61/127 (48%), Gaps = 7/127 (5%)

Query: 31  YDSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFHAAKAYEQAGMMLKEMQK 90
           YD    E  K  V+F+ +++F+Q K++  ++ +  + +  L  +A+  + +    KE QK
Sbjct: 24  YDVKTLEVLKGPVSFQKSQRFKQQKES--KQNLNVDKDTTLPASARKVKSSESK-KESQK 80

Query: 91  LPEAVQLIEKASMMYL-ENGTPDTAAMALERAGKLIENVDPEKAVQLYQQTANVFENEER 149
             + ++++EK   + L E G  D     LE     +E ++      L ++T+    N   
Sbjct: 81  NDKDLKILEKEIRVLLQERGAQDRRIQDLETE---LEKMEARLNAALREKTSLSANNATL 137

Query: 150 LRQAVEL 156
            +Q +EL
Sbjct: 138 EKQLIEL 144


>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
           sapiens]
          Length = 724

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 31/127 (24%), Positives = 59/127 (46%), Gaps = 8/127 (6%)

Query: 31  YDSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFHAAKAYEQAGMMLKEMQK 90
           YD    E  K  V+F+ +++F+Q K++  ++ +  + +  L   A A +      KE QK
Sbjct: 24  YDVKTLEVLKGPVSFQKSQRFKQQKES--KQNLNVDKDTTL--PASARKVKSSESKESQK 79

Query: 91  LPEAVQLIEKASMMYL-ENGTPDTAAMALERAGKLIENVDPEKAVQLYQQTANVFENEER 149
             + ++++EK   + L E G  D     LE     +E ++      L ++T+    N   
Sbjct: 80  NDKDLKILEKEIRVLLQERGAQDRRIQDLETE---LEKMEARLNAALREKTSLSANNATL 136

Query: 150 LRQAVEL 156
            +Q +EL
Sbjct: 137 EKQLIEL 143


>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
          Length = 1478

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 35/162 (21%), Positives = 65/162 (40%), Gaps = 15/162 (9%)

Query: 49   KQFEQAKDACLREAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLEN 108
            ++ + AK+A  RE    E             Q   + +E + L E ++  + A+      
Sbjct: 931  QELQDAKEAASREREGLER------------QVAGLQQEKESLQEKLKAAKAAAGSL--P 976

Query: 109  GTPDTAAMALERAGKLIENVDPEKAVQLYQQTANVFENEERLRQA-VELLGKASRLLVRG 167
            G     A A +RA  L E    E     +Q +A + + + RL+ A  E      +L  +G
Sbjct: 977  GLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQG 1036

Query: 168  RRFDEAALSIQKEKNIYKEIENYPTCYKKTIAQVLVHLHRND 209
            R+   A  +++K K    ++    +C    +A+    + R D
Sbjct: 1037 RQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKD 1078


>gi|21264337 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
            [Homo sapiens]
          Length = 1544

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 18/109 (16%)

Query: 160  ASRLLVRGRRFDEAALSIQKEKNI--YKEIEN-YPTCYKKTIAQVLVHLHRNDYVAA--E 214
            ++RLL R R   EAA   QK + +  YK++    P   ++T+A ++ HL+R    AA  +
Sbjct: 993  SARLLPRWR---EAAELPQKNQRLEKYKDVIGCLPRVNRRTLATLIGHLYRVQKCAALNQ 1049

Query: 215  RCVRE-------SYSIPGFNGSEDCAALEQLLEGYDQQ---DQDQVSDV 253
             C R        S       G  +   L++L++GY      D DQV+ +
Sbjct: 1050 MCTRNLALLFAPSVFQTDGRGEHEVRVLQELIDGYISVFDIDSDQVAQI 1098


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 5/103 (4%)

Query: 32  DSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRA-LFHAAKAYEQAGMMLKEMQK 90
           ++ + E  K+ V  + AK  E+AK     EA + E  ++ +   AK  E+A   +KE  K
Sbjct: 687 EAKSPEKAKSPVK-EEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK 745

Query: 91  LPEAVQLIEKASMMYLENGTPDTAAMALERAGKLIENVDPEKA 133
            PE  +  EKA    L+  +P+    A E A    +   PEKA
Sbjct: 746 SPEKAKSPEKAKT--LDVKSPEAKTPAKEEARSPADKF-PEKA 785


>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
          Length = 1476

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 48/198 (24%), Positives = 85/198 (42%), Gaps = 31/198 (15%)

Query: 7    NEGLEHLAKAEKYLKTGFLKWKPDYDSAASEYGKAAVAFKNA--------KQFEQA---K 55
            +EG +HL +AE+  +        + ++  +E  KA V  K          ++ EQA   +
Sbjct: 851  SEGRQHLEEAERERR--------EKEALQAELEKAVVRGKELGARLEHLQRELEQAALER 902

Query: 56   DACLREAVA-HENNRALFHAAKAYEQAGMMLKE---MQKLPEAVQLIEKASMMYLENGT- 110
               LRE  + H+  + L    +A  QA    KE   M+    A+QL E+  +  L  G  
Sbjct: 903  QEFLREKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEE--LFQLRQGPA 960

Query: 111  ---PDTAA--MALERAGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLV 165
               P   A    +E     +  V+   A+ + ++ A   + +    Q   L G+A  LL+
Sbjct: 961  GLGPKKRAEPQLVETQNVRLIEVERSNAMLVAEKAALQGQLQHLEGQLGSLQGRAQELLL 1020

Query: 166  RGRRFDEAALSIQKEKNI 183
            + +R  E +  +Q EK++
Sbjct: 1021 QSQRAQEHSSRLQAEKSV 1038


>gi|45439327 periplakin [Homo sapiens]
          Length = 1756

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 36/179 (20%), Positives = 71/179 (39%), Gaps = 12/179 (6%)

Query: 5   KINEGLEHLAKAEKYLKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLREA-V 63
           ++ + L+   +    L + F +  PD +   +E  K    F N +Q  + +   L+ A  
Sbjct: 671 EVEQNLQAAKQCSSTLASRFQEHCPDLERQEAEVHKLGQRFNNLRQQVERRAQSLQSAKA 730

Query: 64  AHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALERAGK 123
           A+E+    FH    +    ++     +  E   L +  + +  +    D  A   +   K
Sbjct: 731 AYEH----FHRGHDHVLQFLVSIPSYEPQETDSLSQMETKLKNQKNLLDEIASREQEVQK 786

Query: 124 LIENVDPEKAVQLYQQTANVFENE-ERLRQAVELLGKASRLLVRGRRFDEAALSIQKEK 181
           +  N       Q YQQ    +E E E+LR  ++L    S  + +  R    A  +++E+
Sbjct: 787 ICAN------SQQYQQAVKDYELEAEKLRSLLDLENGRSSHVSKRARLQSPATKVKEEE 839


>gi|12056463 coagulation factor VIII-associated protein [Homo
           sapiens]
          Length = 371

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 46/191 (24%), Positives = 81/191 (42%), Gaps = 24/191 (12%)

Query: 20  LKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFH----AA 75
           LK  FL+ KP+   A  ++G+     +  +    A  A  + AVA    +ALFH    A 
Sbjct: 33  LKKRFLR-KPNVAEAGEQFGQLGRELRAQECLPYA--AWCQLAVAR-CQQALFHGPGEAL 88

Query: 76  KAYEQAGMMLKEM--------------QKLPEAVQLIEKASMMYLENGTP-DTAAMALER 120
              E A + L++               + L  A   +  A  ++LE G P   AA+ LE 
Sbjct: 89  ALTEAARLFLRQERDARQRLVCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLEL 148

Query: 121 AGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQKE 180
           A  L +   P  A   +Q+ A + +  +    A++ LG+A+   +  R +  A     + 
Sbjct: 149 AAALRDLGQPAAAAGHFQRAAQL-QLPQLPLAALQALGEAASCQLLARDYTGALAVFTRM 207

Query: 181 KNIYKEIENYP 191
           + + +E  ++P
Sbjct: 208 QRLAREHGSHP 218


>gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo
           sapiens]
          Length = 1347

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 3/46 (6%)

Query: 181 KNIYKEI---ENYPTCYKKTIAQVLVHLHRNDYVAAERCVRESYSI 223
           K  Y+++   EN P   K T+ Q L  +H N  +  ++  +ESY+I
Sbjct: 222 KEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAI 267


>gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo
           sapiens]
          Length = 1079

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 3/46 (6%)

Query: 181 KNIYKEI---ENYPTCYKKTIAQVLVHLHRNDYVAAERCVRESYSI 223
           K  Y+++   EN P   K T+ Q L  +H N  +  ++  +ESY+I
Sbjct: 222 KEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAI 267


>gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo
           sapiens]
          Length = 1240

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 3/46 (6%)

Query: 181 KNIYKEI---ENYPTCYKKTIAQVLVHLHRNDYVAAERCVRESYSI 223
           K  Y+++   EN P   K T+ Q L  +H N  +  ++  +ESY+I
Sbjct: 222 KEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAI 267


>gi|56090586 coagulation factor VIII-associated (intronic
           transcript) 3 [Homo sapiens]
          Length = 371

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 46/191 (24%), Positives = 81/191 (42%), Gaps = 24/191 (12%)

Query: 20  LKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFH----AA 75
           LK  FL+ KP+   A  ++G+     +  +    A  A  + AVA    +ALFH    A 
Sbjct: 33  LKKRFLR-KPNVAEAGEQFGQLGRELRAQECLPYA--AWCQLAVAR-CQQALFHGPGEAL 88

Query: 76  KAYEQAGMMLKEM--------------QKLPEAVQLIEKASMMYLENGTP-DTAAMALER 120
              E A + L++               + L  A   +  A  ++LE G P   AA+ LE 
Sbjct: 89  ALTEAARLFLRQERDARQRLVCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLEL 148

Query: 121 AGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQKE 180
           A  L +   P  A   +Q+ A + +  +    A++ LG+A+   +  R +  A     + 
Sbjct: 149 AAALRDLGQPAAAAGHFQRAAQL-QLPQLPLAALQALGEAASCQLLARDYTGALAVFTRM 207

Query: 181 KNIYKEIENYP 191
           + + +E  ++P
Sbjct: 208 QRLAREHGSHP 218


>gi|56090588 coagulation factor VIII-associated (intronic
           transcript) 2 [Homo sapiens]
          Length = 371

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 46/191 (24%), Positives = 81/191 (42%), Gaps = 24/191 (12%)

Query: 20  LKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFH----AA 75
           LK  FL+ KP+   A  ++G+     +  +    A  A  + AVA    +ALFH    A 
Sbjct: 33  LKKRFLR-KPNVAEAGEQFGQLGRELRAQECLPYA--AWCQLAVAR-CQQALFHGPGEAL 88

Query: 76  KAYEQAGMMLKEM--------------QKLPEAVQLIEKASMMYLENGTP-DTAAMALER 120
              E A + L++               + L  A   +  A  ++LE G P   AA+ LE 
Sbjct: 89  ALTEAARLFLRQERDARQRLVCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLEL 148

Query: 121 AGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQKE 180
           A  L +   P  A   +Q+ A + +  +    A++ LG+A+   +  R +  A     + 
Sbjct: 149 AAALRDLGQPAAAAGHFQRAAQL-QLPQLPLAALQALGEAASCQLLARDYTGALAVFTRM 207

Query: 181 KNIYKEIENYP 191
           + + +E  ++P
Sbjct: 208 QRLAREHGSHP 218


>gi|32261320 PSMC3 interacting protein isoform 1 [Homo sapiens]
          Length = 205

 Score = 29.6 bits (65), Expect = 3.6
 Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 18/150 (12%)

Query: 38  YGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFHAAKAYEQA-GMMLKEMQKLPEAVQ 96
           YGK  + F +  QF+   DA L+  V      AL    ++ +Q+   M  EMQK    +Q
Sbjct: 65  YGKQKIYFADQDQFDMVSDADLQ--VLDGKIVALTAKVQSLQQSCRYMEAEMQK---EIQ 119

Query: 97  LIEKASMMYLENGTPDTAAMALERAGKLIENVDPEKAVQLYQQTANVF-ENEERLRQAVE 155
            ++K    Y E          L+       +V PE+  Q+Y++      E  +R R A E
Sbjct: 120 ELKKECAGYRER---------LKNIKAATNHVTPEEKEQVYRERQKYCKEWRKRKRMATE 170

Query: 156 LLGKASRLLVRGRR--FDEAALSIQKEKNI 183
           L         + ++  F+E  +   ++ N+
Sbjct: 171 LSDAILEGYPKSKKQFFEEVGIETDEDYNV 200


>gi|55743151 WD repeat domain 19 [Homo sapiens]
          Length = 1342

 Score = 29.6 bits (65), Expect = 3.6
 Identities = 42/169 (24%), Positives = 73/169 (43%), Gaps = 21/169 (12%)

Query: 5    KINEGLEHLAKAEKYLKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLREAVA 64
            K+ + L H++  + +L+    K       A   Y +A VA++NAKQ++    + +R  + 
Sbjct: 884  KVGDLLPHVSSPKIHLQYAKAK------EADGRYKEAVVAYENAKQWQ----SVIRIYLD 933

Query: 65   HENNRA----LFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAM--AL 118
            H NN      +    ++ + A M+ +   +L +    I+   M    N     A     +
Sbjct: 934  HLNNPEKAVNIVRETQSLDGAKMVARFFLQLGDYGSAIQFLVMSKCNNEAFTLAQQHNKM 993

Query: 119  ERAGKLIENVDPEKAVQLYQQTANVFENEERLRQAVE---LLGKASRLL 164
            E    +I + D     + YQ  A  FE E+R  QA +   L G+ SR L
Sbjct: 994  EIYADIIGSEDTTN--EDYQSIALYFEGEKRYLQAGKFFLLCGQYSRAL 1040


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 45/189 (23%), Positives = 79/189 (41%), Gaps = 13/189 (6%)

Query: 64  AHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALERAGK 123
           + EN  A+       E      +E++KL    +LIE+      E    D A   LER  +
Sbjct: 582 SRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEME----EKQKSDKAE--LERMQQ 635

Query: 124 LIENVDPEKAVQLYQQTANVFENEERL-RQAVELLGKASRLLVRGRRFDEAALSIQKEKN 182
            +E    E  +   Q    + + EE L R++  +  K   LL    +F+E  L  Q+E  
Sbjct: 636 EVETQRKETEIVQLQ----IRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIE 691

Query: 183 IYKEIENYPTCYK-KTIAQVLVHLHRNDYVAAERCVRESYSIPGFNGSEDCAALEQLLEG 241
           + K+ +   T  + +   Q L  L+ N+     +  +E   +      E  A LE   + 
Sbjct: 692 LQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQK-EKDEQYAKLELEKKR 750

Query: 242 YDQQDQDQV 250
            ++Q+++QV
Sbjct: 751 LEEQEKEQV 759


>gi|41872403 flavin adenine dinucleotide synthetase isoform 2 [Homo
           sapiens]
          Length = 490

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 34/149 (22%), Positives = 54/149 (36%), Gaps = 24/149 (16%)

Query: 178 QKEKNIYKEIENYPTCYKKTIAQV-LVHLHRNDYVAAERCVRESYSIPGFNGSEDCAALE 236
           Q  + +YK  E+  +  KK    +  +      Y   + CV       GFNG +DC AL 
Sbjct: 264 QASEAVYKLAESGSSLGKKVAGALQTIETSLAQYSLTQLCV-------GFNGGKDCTALL 316

Query: 237 QLLEGYDQQDQDQVSDVCN----------SP---LFKYMDNDYAKLGLSLVVPGGGIKKK 283
            L     Q+   ++ DV N          SP   L +++ +   +  L ++   G +K+ 
Sbjct: 317 HLFHAAVQR---KLPDVPNPLQILYIRSISPFPELEQFLQDTIKRYNLQMLEAEGSMKQA 373

Query: 284 SPATPQAKPDGVTATAADEEEDEYSGGLC 312
                   P            D YS  LC
Sbjct: 374 LGELQARHPQLEAVLMGTRRTDPYSCSLC 402


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,318,529
Number of Sequences: 37866
Number of extensions: 480524
Number of successful extensions: 1380
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 1350
Number of HSP's gapped (non-prelim): 62
length of query: 312
length of database: 18,247,518
effective HSP length: 102
effective length of query: 210
effective length of database: 14,385,186
effective search space: 3020889060
effective search space used: 3020889060
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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