Search of human proteins with 13123778

Search of human proteins with 13123778

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo
sapiens]
         (486 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa...   983   0.0  
gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s...   976   0.0  
gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo s...   967   0.0  
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s...   876   0.0  
gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]          634   0.0  
gi|70780381 bruno-like 6, RNA binding protein [Homo sapiens]          629   e-180
gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa...   609   e-174
gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1 [...   361   e-100
gi|38570081 CUG triplet repeat, RNA-binding protein 1 isoform 2 ...   359   3e-99
gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3 ...   359   3e-99
gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3 ...   357   1e-98
gi|134152680 CUG triplet repeat, RNA binding protein 2 isoform 2...   356   2e-98
gi|225579097 bruno-like 5, RNA binding protein isoform 2 [Homo s...   354   9e-98
gi|134152719 CUG triplet repeat, RNA binding protein 2 isoform 4...   353   1e-97
gi|68303645 CUG triplet repeat, RNA binding protein 2 isoform 1 ...   352   3e-97
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                89   7e-18
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila...    84   3e-16
gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]     83   5e-16
gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]     83   5e-16
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]               80   3e-15
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]               80   3e-15
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]     80   4e-15
gi|93277070 RNA binding motif protein 45 [Homo sapiens]                80   5e-15
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]                      79   7e-15
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]                      79   7e-15
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]                      79   7e-15
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]                      79   7e-15
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]                      79   7e-15
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom...    75   1e-13
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo...    75   1e-13

>gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  983 bits (2540), Expect = 0.0
 Identities = 486/486 (100%), Positives = 486/486 (100%)

Query: 1   MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ 60
           MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ
Sbjct: 1   MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ 60

Query: 61  IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT 120
           IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT
Sbjct: 61  IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT 120

Query: 121 LPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEE 180
           LPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEE
Sbjct: 121 LPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEE 180

Query: 181 CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR 240
           CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR
Sbjct: 181 CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR 240

Query: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMA 300
           MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMA
Sbjct: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMA 300

Query: 301 ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN 360
           ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN
Sbjct: 301 ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN 360

Query: 361 GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEG 420
           GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEG
Sbjct: 361 GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEG 420

Query: 421 CNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 480
           CNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK
Sbjct: 421 CNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 480

Query: 481 DANRPY 486
           DANRPY
Sbjct: 481 DANRPY 486


>gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo
           sapiens]
          Length = 485

 Score =  976 bits (2524), Expect = 0.0
 Identities = 485/486 (99%), Positives = 485/486 (99%), Gaps = 1/486 (0%)

Query: 1   MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ 60
           MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ
Sbjct: 1   MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ 60

Query: 61  IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT 120
           IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT
Sbjct: 61  IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT 120

Query: 121 LPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEE 180
           LPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEE
Sbjct: 121 LPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEE 180

Query: 181 CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR 240
           CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR
Sbjct: 181 CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR 240

Query: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMA 300
           MQQMAGQMGMFNPMAIPFGAYGAYAQA MQQQAALMASVAQGGYLNPMAAFAAAQMQQMA
Sbjct: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQA-MQQQAALMASVAQGGYLNPMAAFAAAQMQQMA 299

Query: 301 ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN 360
           ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN
Sbjct: 300 ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN 359

Query: 361 GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEG 420
           GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEG
Sbjct: 360 GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEG 419

Query: 421 CNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 480
           CNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK
Sbjct: 420 CNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 479

Query: 481 DANRPY 486
           DANRPY
Sbjct: 480 DANRPY 485


>gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo
           sapiens]
          Length = 484

 Score =  967 bits (2501), Expect = 0.0
 Identities = 483/486 (99%), Positives = 483/486 (99%), Gaps = 2/486 (0%)

Query: 1   MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ 60
           MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ
Sbjct: 1   MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ 60

Query: 61  IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT 120
           IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT
Sbjct: 61  IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT 120

Query: 121 LPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEE 180
           LPGMNRPIQVKPADSESRGGSSCLRQPPS  RKLFVGMLNKQQSEDDVRRLFEAFGNIEE
Sbjct: 121 LPGMNRPIQVKPADSESRGGSSCLRQPPSH-RKLFVGMLNKQQSEDDVRRLFEAFGNIEE 179

Query: 181 CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR 240
           CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR
Sbjct: 180 CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR 239

Query: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMA 300
           MQQMAGQMGMFNPMAIPFGAYGAYAQA MQQQAALMASVAQGGYLNPMAAFAAAQMQQMA
Sbjct: 240 MQQMAGQMGMFNPMAIPFGAYGAYAQA-MQQQAALMASVAQGGYLNPMAAFAAAQMQQMA 298

Query: 301 ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN 360
           ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN
Sbjct: 299 ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN 358

Query: 361 GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEG 420
           GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEG
Sbjct: 359 GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEG 418

Query: 421 CNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 480
           CNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK
Sbjct: 419 CNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 478

Query: 481 DANRPY 486
           DANRPY
Sbjct: 479 DANRPY 484


>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
           sapiens]
          Length = 448

 Score =  876 bits (2264), Expect = 0.0
 Identities = 447/486 (91%), Positives = 448/486 (92%), Gaps = 38/486 (7%)

Query: 1   MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ 60
           MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ
Sbjct: 1   MYIKMATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQ 60

Query: 61  IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT 120
           IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT
Sbjct: 61  IPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKT 120

Query: 121 LPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEE 180
           LPGMNRPIQVKPADSESRG          +DRKLFVGMLNKQQSEDDVRRLFEAFGNIEE
Sbjct: 121 LPGMNRPIQVKPADSESRG----------EDRKLFVGMLNKQQSEDDVRRLFEAFGNIEE 170

Query: 181 CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR 240
           CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR
Sbjct: 171 CTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRR 230

Query: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMA 300
           MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMA
Sbjct: 231 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMA 290

Query: 301 ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN 360
           ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN
Sbjct: 291 ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFAN 350

Query: 361 GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEG 420
           GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQRE    
Sbjct: 351 GIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQRE---- 406

Query: 421 CNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 480
                                   GFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK
Sbjct: 407 ------------------------GFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 442

Query: 481 DANRPY 486
           DANRPY
Sbjct: 443 DANRPY 448


>gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]
          Length = 465

 Score =  634 bits (1636), Expect = 0.0
 Identities = 319/479 (66%), Positives = 377/479 (78%), Gaps = 54/479 (11%)

Query: 48  MKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERES 107
           MK+ DAIKLF+GQIPR+L+EKDLKP+FE+FG+I+ELTV+KD++TG+HKGCAFLTYC R+S
Sbjct: 1   MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDS 60

Query: 108 ALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDD 167
           ALKAQSALHEQKTLPGMNRPIQVKPADSESRG          +DRKLFVGML KQQ+++D
Sbjct: 61  ALKAQSALHEQKTLPGMNRPIQVKPADSESRG----------EDRKLFVGMLGKQQTDED 110

Query: 168 VRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVV 227
           VR++FE FG I+ECT+LRGPDG SKGCAFVK+ +HAEAQAAIN LH S+T+PGASSSLVV
Sbjct: 111 VRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSSLVV 170

Query: 228 KFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNP 287
           KFADT+KER +RRMQQ+A Q+GMF+P+A+ FGAY AY QALMQQQAAL+A  A   YL+P
Sbjct: 171 KFADTEKERGLRRMQQVATQLGMFSPIALQFGAYSAYTQALMQQQAALVA--AHSAYLSP 228

Query: 288 MAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQ 347
           MA  AA QMQ MAA+N NGL A P+TP+SG STPP I A  V +IP+ +GVNG++ +P Q
Sbjct: 229 MATMAAVQMQHMAAINANGLIATPITPSSGTSTPPAIAATPVSAIPAALGVNGYSPVPTQ 288

Query: 348 ANGQPAAEAVFANGIHPYPAQSPTA-ADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQP 406
             GQPA +A++ NG+HPYPAQSP A  DPLQQAYAG+Q Y   AAYPAAY  ++ AFPQP
Sbjct: 289 PTGQPAPDALYPNGVHPYPAQSPAAPVDPLQQAYAGMQHYT--AAYPAAYSLVAPAFPQP 346

Query: 407 PPMI-------------------PQQQREGPEGCNLFIYHLPQEFGDAELMQMFLP---- 443
           P ++                    QQQREGP+GCN+FIYHLPQEF D+E++QMF+P    
Sbjct: 347 PALVAQQPPPPPQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHV 406

Query: 444 ----------------FGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 486
                           FGFVSFDNPASAQ AIQAMNGFQIGMKRLKVQLKRPKDANRPY
Sbjct: 407 ISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY 465


>gi|70780381 bruno-like 6, RNA binding protein [Homo sapiens]
          Length = 481

 Score =  629 bits (1621), Expect = e-180
 Identities = 331/503 (65%), Positives = 376/503 (74%), Gaps = 43/503 (8%)

Query: 5   MATLANGQADNASLSTNGLGSSPGSAG-HMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPR 63
           MA    G A  A      LG S   +G  M+GL+  P     +PMKDHDAIKLF+GQIPR
Sbjct: 1   MAAAPGGSAQPAGPGPR-LGFSTADSGVGMSGLNPGPA----VPMKDHDAIKLFVGQIPR 55

Query: 64  NLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPG 123
            LDE+DLKPLFEEFG+IYELTVLKDR TG+HKGCAFLTYC R+SALKAQSALHEQKTLPG
Sbjct: 56  GLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPG 115

Query: 124 MNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTI 183
           MNRPIQVKPA SE RG          +DRKLFVGML KQQ E+DVRRLF+ FG+IEECT+
Sbjct: 116 MNRPIQVKPAASEGRG----------EDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTV 165

Query: 184 LRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQ 243
           LR PDG SKGCAFVK+ S  EAQAAI  LHGS+TM GASSSLVVK ADTD+ER +RRMQQ
Sbjct: 166 LRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRRMQQ 225

Query: 244 MAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALN 303
           MAG +G F+P  +P GA GAY  A++Q QAAL+A+ AQG  L P+AA  AAQMQ +AA +
Sbjct: 226 MAGHLGAFHPAPLPLGACGAYTTAILQHQAALLAA-AQGPGLGPVAA-VAAQMQHVAAFS 283

Query: 304 MNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIH 363
              L AAP+ P +  ++PPG     +P +P+PIGVNGF  L PQ NGQP ++ ++ NG+ 
Sbjct: 284 ---LVAAPLLPAAAANSPPGSGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLS 340

Query: 364 PYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNL 423
           PYPAQSP  ADPLQQAYAG+  YA  AAYP+AY  +S AFPQ P  +PQQQREGPEGCNL
Sbjct: 341 PYPAQSPGVADPLQQAYAGMHHYA--AAYPSAYAPVSTAFPQQPSALPQQQREGPEGCNL 398

Query: 424 FIYHLPQEFGDAELMQMFLP--------------------FGFVSFDNPASAQTAIQAMN 463
           FIYHLPQEFGDAEL+Q FLP                    FGFVSFDNP SAQTAIQAMN
Sbjct: 399 FIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMN 458

Query: 464 GFQIGMKRLKVQLKRPKDANRPY 486
           GFQIGMKRLKVQLKRPKDANRPY
Sbjct: 459 GFQIGMKRLKVQLKRPKDANRPY 481


>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
           sapiens]
          Length = 485

 Score =  609 bits (1571), Expect = e-174
 Identities = 317/474 (66%), Positives = 364/474 (76%), Gaps = 38/474 (8%)

Query: 37  SHSPGNPSTIP--MKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMH 94
           S  P  P   P  MKD DAIKLF+GQIPR+LDEKDLKPLFE+FG+IYELTVLKD +TGMH
Sbjct: 26  SSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMH 85

Query: 95  KGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKL 154
           KGCAFLTYC R+SA+KAQ+ALHEQKTLPGM RPIQVKPADSESRGG         +DRKL
Sbjct: 86  KGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGG---------RDRKL 136

Query: 155 FVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHG 214
           FVGMLNKQQSE+DV RLF+ FG I+ECT+LRGPDG+SKGCAFVK+SSH EAQAAI+ALHG
Sbjct: 137 FVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHG 196

Query: 215 SQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNP-MAIPFGAYGAYAQALMQQQA 273
           SQTMPGASSSLVVKFADTDKERT+RRMQQM GQ+G+  P + +PF  Y AYAQALMQQQ 
Sbjct: 197 SQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLPFSPYSAYAQALMQQQT 256

Query: 274 ALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIP 333
            ++++   G YL+P  AF+   +QQ+ A+++NGL A P+ P SG  +PP +   AVP + 
Sbjct: 257 TVLST--SGSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLHSPPLLGTTAVPGLV 314

Query: 334 SPIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYP 393
           +PI  NGF G+ P   G PA E V+ANG+ PYPAQSPT A+ L  A++GVQQY   A YP
Sbjct: 315 API-TNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAFSGVQQYT--AMYP 371

Query: 394 -AAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLP--------- 443
            AA   I+ + PQPPP++ QQQREGPEGCNLFIYHLPQEFGD EL QMFLP         
Sbjct: 372 TAAITPIAHSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKV 431

Query: 444 -----------FGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 486
                      FGFVSFDNPASAQ AIQAMNGFQIGMKRLKVQLKRPKD   PY
Sbjct: 432 FMDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDPGHPY 485


>gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1
           [Homo sapiens]
          Length = 482

 Score =  361 bits (927), Expect = e-100
 Identities = 223/502 (44%), Positives = 288/502 (57%), Gaps = 68/502 (13%)

Query: 33  MNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTG 92
           MNG    P  P      D DAIK+F+GQ+PR   EKDL+ LFE++G +YE+ VL+DR   
Sbjct: 1   MNGTLDHPDQP------DLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQN 54

Query: 93  --MHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQ 150
               KGC F+T+  R++AL+AQ+ALH  K LPGM+ PIQ+KPADSE             +
Sbjct: 55  PPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAV--------E 106

Query: 151 DRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAIN 210
           DRKLF+GM++K+ +E+D+R +F +FG IEEC ILRGPDG S+GCAFV +++ A AQ AI 
Sbjct: 107 DRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIK 166

Query: 211 ALHGSQTMPGASSSLVVKFADTDKERTMRRM-QQMAGQMGMFNPMAIPFGAYGAYAQALM 269
           A+H +QTM G SS +VVKFADT K++  +RM QQ+  QM   +  ++     G     L 
Sbjct: 167 AMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAG--LNTLG 224

Query: 270 QQQAALMASVAQGGYLN------PMAAFAAAQMQQMAALNMNGLAAAPMTP--------- 314
            Q  AL+   A  G LN      PM    A Q+Q +AAL     +AA  TP         
Sbjct: 225 PQYLALLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAAL-AAAASAAQNTPSGTNALTTS 283

Query: 315 -------TSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQAN-GQPAAEAVFANGIHPYP 366
                  TS GS+P   ++ +V  I S   +    G     N G  A  A    G+    
Sbjct: 284 SSPLSVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSG 343

Query: 367 AQSPTAA--DPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLF 424
             + T +  + L QAY+G+QQYA  AA P  Y Q      Q        Q+EGPEG NLF
Sbjct: 344 LSNGTGSTMEALTQAYSGIQQYAA-AALPTLYNQ--NLLTQQSIGAAGSQKEGPEGANLF 400

Query: 425 IYHLPQEFGDAELMQMFLP--------------------FGFVSFDNPASAQTAIQAMNG 464
           IYHLPQEFGD +L+QMF+P                    FGFVS+DNP SAQ AIQ+MNG
Sbjct: 401 IYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNG 460

Query: 465 FQIGMKRLKVQLKRPKDANRPY 486
           FQIGMKRLKVQLKR K+ ++PY
Sbjct: 461 FQIGMKRLKVQLKRSKNDSKPY 482


>gi|38570081 CUG triplet repeat, RNA-binding protein 1 isoform 2
           [Homo sapiens]
          Length = 483

 Score =  359 bits (922), Expect = 3e-99
 Identities = 222/503 (44%), Positives = 288/503 (57%), Gaps = 69/503 (13%)

Query: 33  MNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTG 92
           MNG    P  P      D DAIK+F+GQ+PR   EKDL+ LFE++G +YE+ VL+DR   
Sbjct: 1   MNGTLDHPDQP------DLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQN 54

Query: 93  --MHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQ 150
               KGC F+T+  R++AL+AQ+ALH  K LPGM+ PIQ+KPADSE             +
Sbjct: 55  PPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAV--------E 106

Query: 151 DRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAIN 210
           DRKLF+GM++K+ +E+D+R +F +FG IEEC ILRGPDG S+GCAFV +++ A AQ AI 
Sbjct: 107 DRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIK 166

Query: 211 ALHGSQTMPGASSSLVVKFADTDKERTMRRM-QQMAGQMGMFNPMAIPFGAYGAYAQALM 269
           A+H +QTM G SS +VVKFADT K++  +RM QQ+  QM   +  ++     G     L 
Sbjct: 167 AMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAG--LNTLG 224

Query: 270 QQQAALMASVAQGGYLN------PMAAFAAAQMQQMAALNMNGLAAAPMTP--------- 314
            Q  AL+   A  G LN      PM    A Q+Q +AAL     +AA  TP         
Sbjct: 225 PQYLALLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAAL-AAAASAAQNTPSGTNALTTS 283

Query: 315 --------TSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQAN-GQPAAEAVFANGIHPY 365
                   +S GS+P   ++ +V  I S   +    G     N G  A  A    G+   
Sbjct: 284 SSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSS 343

Query: 366 PAQSPTAA--DPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNL 423
              + T +  + L QAY+G+QQYA  AA P  Y Q      Q        Q+EGPEG NL
Sbjct: 344 GLSNGTGSTMEALTQAYSGIQQYAA-AALPTLYNQ--NLLTQQSIGAAGSQKEGPEGANL 400

Query: 424 FIYHLPQEFGDAELMQMFLP--------------------FGFVSFDNPASAQTAIQAMN 463
           FIYHLPQEFGD +L+QMF+P                    FGFVS+DNP SAQ AIQ+MN
Sbjct: 401 FIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMN 460

Query: 464 GFQIGMKRLKVQLKRPKDANRPY 486
           GFQIGMKRLKVQLKR K+ ++PY
Sbjct: 461 GFQIGMKRLKVQLKRSKNDSKPY 483


>gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3
           [Homo sapiens]
          Length = 508

 Score =  359 bits (922), Expect = 3e-99
 Identities = 230/517 (44%), Positives = 296/517 (57%), Gaps = 82/517 (15%)

Query: 26  SPGSAGHMNG-LSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELT 84
           S G+A  MNG L HS          D DAIK+F+GQIPR+  EK+LK LFE +G +Y++ 
Sbjct: 18  SNGTANKMNGALDHSD-------QPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQIN 70

Query: 85  VLKDRFTG--MHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSS 142
           VL+DR       KGC F+T+  R++AL+AQ+ALH  KTLPGM+ PIQ+KPADSE      
Sbjct: 71  VLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAV- 129

Query: 143 CLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSH 202
                  +DRKLF+GM++K+ +E+D+R +F  FG IEEC ILRGPDG S+GCAFV +S+ 
Sbjct: 130 -------EDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTR 182

Query: 203 AEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRM-QQMAGQMGMFNPMAIP--FG 259
           A AQ AI A+H SQTM G SS +VVKFADT K++  RR+ QQ+A QM   N        G
Sbjct: 183 AMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTG 242

Query: 260 AYGAYAQAL-MQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGG 318
             G   Q L + QQA   +++     +  MA   A Q+Q +A L     AAA  + TS  
Sbjct: 243 LGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATL-AAAAAAAQTSATSTN 301

Query: 319 STPPGITAPAVPSIPSPIG--------------------VNGFTGLPPQAN--GQPAAEA 356
           + P   T+ A+ ++ SP+                     + G  G     N     A  A
Sbjct: 302 ANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAGMA 361

Query: 357 VFANGIHPYPAQSPTAA--DPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQ- 413
               G+      + TA   D L QAY+G+QQYA  AA P  Y Q          ++ QQ 
Sbjct: 362 ALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAA-AALPTLYSQ---------SLLQQQS 411

Query: 414 ----QREGPEGCNLFIYHLPQEFGDAELMQMFLP--------------------FGFVSF 449
               Q+EGPEG NLFIYHLPQEFGD +++QMF+P                    FGFVS+
Sbjct: 412 AAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSY 471

Query: 450 DNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 486
           DNP SAQ AIQAMNGFQIGMKRLKVQLKR K+ ++PY
Sbjct: 472 DNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY 508


>gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3
           [Homo sapiens]
          Length = 486

 Score =  357 bits (916), Expect = 1e-98
 Identities = 221/504 (43%), Positives = 289/504 (57%), Gaps = 68/504 (13%)

Query: 33  MNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTG 92
           MNG    P  P      D DAIK+F+GQ+PR   EKDL+ LFE++G +YE+ VL+DR   
Sbjct: 1   MNGTLDHPDQP------DLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQN 54

Query: 93  --MHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQ 150
               KGC F+T+  R++AL+AQ+ALH  K LPGM+ PIQ+KPADSE             +
Sbjct: 55  PPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAV--------E 106

Query: 151 DRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAIN 210
           DRKLF+GM++K+ +E+D+R +F +FG IEEC ILRGPDG S+GCAFV +++ A AQ AI 
Sbjct: 107 DRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIK 166

Query: 211 ALHGSQTMPGASSSLVVKFADTDKERTMRRM-QQMAGQMGMFNPMAI-----PFGAYGAY 264
           A+H +QTM G SS +VVKFADT K++  +RM QQ+  QM   +  ++          G  
Sbjct: 167 AMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQ 226

Query: 265 AQAL---MQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTP------- 314
             AL   + QQ A   ++     L+PM    A Q+Q +AAL     +AA  TP       
Sbjct: 227 YLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAAL-AAAASAAQNTPSGTNALT 285

Query: 315 ---------TSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQAN-GQPAAEAVFANGIHP 364
                    TS GS+P   ++ +V  I S   +    G     N G  A  A    G+  
Sbjct: 286 TSSSPLSVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGS 345

Query: 365 YPAQSPTAA--DPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCN 422
               + T +  + L QAY+G+QQYA  AA P  Y Q      Q        Q+EGPEG N
Sbjct: 346 SGLSNGTGSTMEALTQAYSGIQQYAA-AALPTLYNQ--NLLTQQSIGAAGSQKEGPEGAN 402

Query: 423 LFIYHLPQEFGDAELMQMFLP--------------------FGFVSFDNPASAQTAIQAM 462
           LFIYHLPQEFGD +L+QMF+P                    FGFVS+DNP SAQ AIQ+M
Sbjct: 403 LFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSM 462

Query: 463 NGFQIGMKRLKVQLKRPKDANRPY 486
           NGFQIGMKRLKVQLKR K+ ++PY
Sbjct: 463 NGFQIGMKRLKVQLKRSKNDSKPY 486


>gi|134152680 CUG triplet repeat, RNA binding protein 2 isoform 2
           [Homo sapiens]
          Length = 521

 Score =  356 bits (914), Expect = 2e-98
 Identities = 230/521 (44%), Positives = 297/521 (57%), Gaps = 88/521 (16%)

Query: 28  GSAGHMNG-LSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVL 86
           G+A  MNG L HS          D DAIK+F+GQIPR+  EK+LK LFE +G +Y++ VL
Sbjct: 27  GTANKMNGALDHSD-------QPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVL 79

Query: 87  KDRFTG--MHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCL 144
           +DR       KGC F+T+  R++AL+AQ+ALH  KTLPGM+ PIQ+KPADSE        
Sbjct: 80  RDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAV--- 136

Query: 145 RQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAE 204
                +DRKLF+GM++K+ +E+D+R +F  FG IEEC ILRGPDG S+GCAFV +S+ A 
Sbjct: 137 -----EDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAM 191

Query: 205 AQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQ-MAGQMGMFNPMAIP--FGAY 261
           AQ AI A+H SQTM G SS +VVKFADT K++  RR+QQ +A QM   N        G  
Sbjct: 192 AQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLG 251

Query: 262 GAYAQAL-MQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGST 320
           G   Q L + QQA   +++     +  MA   A Q+Q +A L     AAA  + TS  + 
Sbjct: 252 GLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAA-AAAAAQTSATSTNAN 310

Query: 321 PPGITAPAVPSIPSPIG-----------VNGFTGLPP------------QANGQPAAE-- 355
           P   T+ A+ ++ SP+            +N  T L                N    A+  
Sbjct: 311 PLSTTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAVAQML 370

Query: 356 ---AVFANGIHPYPAQSPTAA--DPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMI 410
              A    G+      + TA   D L QAY+G+QQYA  AA P  Y Q          ++
Sbjct: 371 SGMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAA-AALPTLYSQ---------SLL 420

Query: 411 PQQ-----QREGPEGCNLFIYHLPQEFGDAELMQMFLPFG-------------------- 445
            QQ     Q+EGPEG NLFIYHLPQEFGD +++QMF+PFG                    
Sbjct: 421 QQQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFG 480

Query: 446 FVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 486
           FVS+DNP SAQ AIQAMNGFQIGMKRLKVQLKR K+ ++PY
Sbjct: 481 FVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY 521



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 40/142 (28%), Positives = 68/142 (47%), Gaps = 6/142 (4%)

Query: 127 PIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRG 186
           P ++    ++  G      QP     K+FVG + +  SE +++ LFE +G + +  +LR 
Sbjct: 22  PDRINGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRD 81

Query: 187 PDGN---SKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQ 243
              N   SKGC FV + +   A  A NALH  +T+PG    + +K AD++K   +   + 
Sbjct: 82  RSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKL 141

Query: 244 MAGQMGM---FNPMAIPFGAYG 262
             G +      N + + F  +G
Sbjct: 142 FIGMVSKKCNENDIRVMFSPFG 163


>gi|225579097 bruno-like 5, RNA binding protein isoform 2 [Homo
           sapiens]
          Length = 320

 Score =  354 bits (909), Expect = 9e-98
 Identities = 185/296 (62%), Positives = 224/296 (75%), Gaps = 16/296 (5%)

Query: 124 MNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTI 183
           M RPIQVKPADSESRGG         +DRKLFVGMLNKQQSE+DV RLF+ FG I+ECT+
Sbjct: 1   MARPIQVKPADSESRGG---------RDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTV 51

Query: 184 LRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQ 243
           LRGPDG+SKGCAFVK+SSH EAQAAI+ALHGSQTMPGASSSLVVKFADTDKERT+RRMQQ
Sbjct: 52  LRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQ 111

Query: 244 MAGQMGMFNP-MAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAAL 302
           M GQ+G+  P + +PF  Y AYAQALMQQQ  ++++   G YL+P  AF+   +QQ+ A+
Sbjct: 112 MVGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLST--SGSYLSPGVAFSPCHIQQIGAV 169

Query: 303 NMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGI 362
           ++NGL A P+ P SG  +PP +   AVP + +PI  NGF G+ P   G PA E V+ANG+
Sbjct: 170 SLNGLPATPIAPASGLHSPPLLGTTAVPGLVAPI-TNGFAGVVPFPGGHPALETVYANGL 228

Query: 363 HPYPAQSPTAADPLQQAYAGVQQYAGPAAYP-AAYGQISQAFPQPPPMIPQQQREG 417
            PYPAQSPT A+ L  A++GVQQY   A YP AA   I+ + PQPPP++ QQQREG
Sbjct: 229 VPYPAQSPTVAETLHPAFSGVQQYT--AMYPTAAITPIAHSVPQPPPLLQQQQREG 282


>gi|134152719 CUG triplet repeat, RNA binding protein 2 isoform 4
           [Homo sapiens]
          Length = 488

 Score =  353 bits (907), Expect = 1e-97
 Identities = 227/514 (44%), Positives = 293/514 (57%), Gaps = 86/514 (16%)

Query: 33  MNG-LSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFT 91
           MNG L HS          D DAIK+F+GQIPR+  EK+LK LFE +G +Y++ VL+DR  
Sbjct: 1   MNGALDHSD-------QPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQ 53

Query: 92  G--MHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPS 149
                KGC F+T+  R++AL+AQ+ALH  KTLPGM+ PIQ+KPADSE             
Sbjct: 54  NPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAV-------- 105

Query: 150 QDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAI 209
           +DRKLF+GM++K+ +E+D+R +F  FG IEEC ILRGPDG S+GCAFV +S+ A AQ AI
Sbjct: 106 EDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAI 165

Query: 210 NALHGSQTMPGASSSLVVKFADTDKERTMRRMQQ-MAGQMGMFNPMAIP--FGAYGAYAQ 266
            A+H SQTM G SS +VVKFADT K++  RR+QQ +A QM   N        G  G   Q
Sbjct: 166 KAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQ 225

Query: 267 AL-MQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGIT 325
            L + QQA   +++     +  MA   A Q+Q +A L     AAA  + TS  + P   T
Sbjct: 226 YLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAA-AAAAAQTSATSTNANPLSTT 284

Query: 326 APAVPSIPSPIGVN--------------------GFTGLPPQAN------GQPAAEAVFA 359
           + A+ ++ SP+  +                    G  G     N      G   + A   
Sbjct: 285 SSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAGTINSMAALN 344

Query: 360 NGIHPYPAQSPTAA--DPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQ---- 413
            G+      + TA   D L QAY+G+QQYA  AA P  Y Q          ++ QQ    
Sbjct: 345 GGLGATGLTNGTAGTMDALTQAYSGIQQYAA-AALPTLYSQ---------SLLQQQSAAG 394

Query: 414 -QREGPEGCNLFIYHLPQEFGDAELMQMFLPFG--------------------FVSFDNP 452
            Q+EGPEG NLFIYHLPQEFGD +++QMF+PFG                    FVS+DNP
Sbjct: 395 SQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNP 454

Query: 453 ASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 486
            SAQ AIQAMNGFQIGMKRLKVQLKR K+ ++PY
Sbjct: 455 VSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY 488


>gi|68303645 CUG triplet repeat, RNA binding protein 2 isoform 1
           [Homo sapiens]
          Length = 490

 Score =  352 bits (904), Expect = 3e-97
 Identities = 228/516 (44%), Positives = 294/516 (56%), Gaps = 88/516 (17%)

Query: 33  MNG-LSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFT 91
           MNG L HS          D DAIK+F+GQIPR+  EK+LK LFE +G +Y++ VL+DR  
Sbjct: 1   MNGALDHSD-------QPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQ 53

Query: 92  G--MHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPS 149
                KGC F+T+  R++AL+AQ+ALH  KTLPGM+ PIQ+KPADSE             
Sbjct: 54  NPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAV-------- 105

Query: 150 QDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAI 209
           +DRKLF+GM++K+ +E+D+R +F  FG IEEC ILRGPDG S+GCAFV +S+ A AQ AI
Sbjct: 106 EDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAI 165

Query: 210 NALHGSQTMPGASSSLVVKFADTDKERTMRRMQQ-MAGQMGMFNPMAIP--FGAYGAYAQ 266
            A+H SQTM G SS +VVKFADT K++  RR+QQ +A QM   N        G  G   Q
Sbjct: 166 KAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQ 225

Query: 267 AL-MQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGIT 325
            L + QQA   +++     +  MA   A Q+Q +A L     AAA  + TS  + P   T
Sbjct: 226 YLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAA-AAAAAQTSATSTNANPLSTT 284

Query: 326 APAVPSIPSPIG-----------VNGFTGLPP------------QANGQPAAE-----AV 357
           + A+ ++ SP+            +N  T L                N    A+     A 
Sbjct: 285 SSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAVAQMLSGMAA 344

Query: 358 FANGIHPYPAQSPTAA--DPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQ-- 413
              G+      + TA   D L QAY+G+QQYA  AA P  Y Q          ++ QQ  
Sbjct: 345 LNGGLGATGLTNGTAGTMDALTQAYSGIQQYAA-AALPTLYSQ---------SLLQQQSA 394

Query: 414 ---QREGPEGCNLFIYHLPQEFGDAELMQMFLPFG--------------------FVSFD 450
              Q+EGPEG NLFIYHLPQEFGD +++QMF+PFG                    FVS+D
Sbjct: 395 AGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYD 454

Query: 451 NPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 486
           NP SAQ AIQAMNGFQIGMKRLKVQLKR K+ ++PY
Sbjct: 455 NPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY 490


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 99/372 (26%), Positives = 151/372 (40%), Gaps = 41/372 (11%)

Query: 46  IPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCER 105
           I  ++ DA  +++G +   + E  L  LF + G +    + KDR TG H+G  F+ +   
Sbjct: 6   ISERNQDAT-VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64

Query: 106 ESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSE 165
           E    A  A+     +    +PI+V  A + ++               +F+G L+ +  E
Sbjct: 65  ED---ADYAIKIMNMIKLYGKPIRVNKASAHNKN--------LDVGANIFIGNLDPEIDE 113

Query: 166 DDVRRLFEAFGNI-EECTILRGPD-GNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASS 223
             +   F AFG I +   I+R PD GNSKG AF+ ++S   + AAI A++G       + 
Sbjct: 114 KLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYL---CNR 170

Query: 224 SLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGG 283
            + V +A     +  R        +   NP++     +  +A A     A      + G 
Sbjct: 171 PITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGS 230

Query: 284 YLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTG 343
            L P              +   G    P+ P   G+ PPGI  PA+P  P P G  G   
Sbjct: 231 GLPP------------PGMPPPGSFPPPVPPP--GALPPGI-PPAMPPPPMPPGAAGHG- 274

Query: 344 LPPQANGQPAAEAVFANGIHPYPAQSPTAADP----LQQAYAGVQQYAGPAAYPAAYGQI 399
            PP A G P A        HP+P        P    +Q A+ G      P A P   G  
Sbjct: 275 -PPSA-GTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSG-- 330

Query: 400 SQAFPQPPPMIP 411
            Q  P+PPP +P
Sbjct: 331 GQPPPRPPPGMP 342


>gi|115511032 ELAV (embryonic lethal, abnormal vision,
           Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
          Length = 359

 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 60/219 (27%), Positives = 108/219 (49%), Gaps = 17/219 (7%)

Query: 23  LGSSPGSAGHMNG---LSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGK 79
           L + P      NG   ++++  +P      +     L +  +P+N+ +++LK LF   G+
Sbjct: 5   LSNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGE 64

Query: 80  IYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRG 139
           I    +++D+ TG   G  F+ Y + + A KA + L+  +      + I+V    S +R 
Sbjct: 65  IESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL---QTKTIKV----SYARP 117

Query: 140 GSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVK 198
            S+ +R     D  L+V  L K  ++ ++ +LF  +G I    IL     G S+G  F++
Sbjct: 118 SSASIR-----DANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIR 172

Query: 199 YSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERT 237
           +    EA+ AI  L+G Q  PGA+  + VKFA+   ++T
Sbjct: 173 FDKRIEAEEAIKGLNG-QKPPGATEPITVKFANNPSQKT 210



 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 85/366 (23%), Positives = 132/366 (36%), Gaps = 90/366 (24%)

Query: 154 LFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINAL 212
           L V  L +  ++++++ LF + G IE C ++R    G S G  FV Y    +A+ AIN L
Sbjct: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100

Query: 213 HG----------SQTMPGASS--SLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGA 260
           +G          S   P ++S     +  +   K  T + ++Q+  Q G      I    
Sbjct: 101 NGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI---- 156

Query: 261 YGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGST 320
                  L+ Q   +   V           F     +  A   + GL          G  
Sbjct: 157 -------LVDQVTGISRGVG----------FIRFDKRIEAEEAIKGL---------NGQK 190

Query: 321 PPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPYP------AQSPTAAD 374
           PPG T P             F   P Q   Q     ++ +    YP      AQ     +
Sbjct: 191 PPGATEPITVK---------FANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDN 241

Query: 375 PLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGD 434
            L  AY GV++++ P              P  P         G   C +F+Y+L  +  +
Sbjct: 242 LLNMAY-GVKRFS-PMTIDGMTSLAGINIPGHP---------GTGWC-IFVYNLAPDADE 289

Query: 435 AELMQMFLPFG--------------------FVSFDNPASAQTAIQAMNGFQIGMKRLKV 474
           + L QMF PFG                    FV+  N   A  AI ++NG+++G + L+V
Sbjct: 290 SILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQV 349

Query: 475 QLKRPK 480
             K  K
Sbjct: 350 SFKTNK 355



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 37/125 (29%), Positives = 68/125 (54%), Gaps = 5/125 (4%)

Query: 39  SPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCA 98
           S   PS+  ++D +   L++  +P+ + +K+L+ LF ++G+I    +L D+ TG+ +G  
Sbjct: 113 SYARPSSASIRDAN---LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVG 169

Query: 99  FLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSES-RGGSSCLRQPPSQDRKLFVG 157
           F+ + +R  A +A   L+ QK  PG   PI VK A++ S +   + L Q      + + G
Sbjct: 170 FIRFDKRIEAEEAIKGLNGQKP-PGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPG 228

Query: 158 MLNKQ 162
            L +Q
Sbjct: 229 PLAQQ 233



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 20/82 (24%)

Query: 422 NLFIYHLPQEFGDAELMQMF--------------------LPFGFVSFDNPASAQTAIQA 461
           NL + +LPQ     EL  +F                    L +GFV++ +P  A+ AI  
Sbjct: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99

Query: 462 MNGFQIGMKRLKVQLKRPKDAN 483
           +NG ++  K +KV   RP  A+
Sbjct: 100 LNGLRLQTKTIKVSYARPSSAS 121



 Score = 32.7 bits (73), Expect = 0.76
 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 9/93 (9%)

Query: 26  SPGSAGHMNGLS--HSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYEL 83
           SP +   M  L+  + PG+P T          +F+  +  + DE  L  +F  FG +  +
Sbjct: 253 SPMTIDGMTSLAGINIPGHPGT-------GWCIFVYNLAPDADESILWQMFGPFGAVTNV 305

Query: 84  TVLKDRFTGMHKGCAFLTYCERESALKAQSALH 116
            V++D  T   KG  F+T    + A  A ++L+
Sbjct: 306 KVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLN 338


>gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]
          Length = 439

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 85/328 (25%), Positives = 142/328 (43%), Gaps = 65/328 (19%)

Query: 25  SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75
           S P + G+  G S SP      P+++          DA  +F  Q+   +  +DL+  F 
Sbjct: 128 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 187

Query: 76  EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135
             GK+ ++ ++ DR +   KG A++ +CE +S   A     ++  L G+   +Q   A+ 
Sbjct: 188 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQR--LLGVPIIVQASQAEK 245

Query: 136 ESRGG-SSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNSKG 193
                 ++ L++      +L+VG L+   +ED +R +FE FG I+   +++  D G SKG
Sbjct: 246 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 305

Query: 194 CAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTMRR 240
             F+ +S    A+ A+  L+G             ++ + G +    + F D D+E     
Sbjct: 306 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE----- 357

Query: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGG--YLNPMAAFAAAQMQQ 298
                          +  G+ G   Q        LMA +A+G    L   AA AAA   Q
Sbjct: 358 ---------------LDLGSAGGRFQ--------LMAKLAEGAGIQLPSTAAAAAAAAAQ 394

Query: 299 MAALNMNGLAAAPMTPTSGGSTPPGITA 326
            AAL +NG  A P+    G   P  +TA
Sbjct: 395 AAALQLNG--AVPL----GALNPAALTA 416


>gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]
          Length = 423

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 85/328 (25%), Positives = 142/328 (43%), Gaps = 65/328 (19%)

Query: 25  SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75
           S P + G+  G S SP      P+++          DA  +F  Q+   +  +DL+  F 
Sbjct: 112 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 171

Query: 76  EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135
             GK+ ++ ++ DR +   KG A++ +CE +S   A     ++  L G+   +Q   A+ 
Sbjct: 172 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQR--LLGVPIIVQASQAEK 229

Query: 136 ESRGG-SSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNSKG 193
                 ++ L++      +L+VG L+   +ED +R +FE FG I+   +++  D G SKG
Sbjct: 230 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 289

Query: 194 CAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTMRR 240
             F+ +S    A+ A+  L+G             ++ + G +    + F D D+E     
Sbjct: 290 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE----- 341

Query: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGG--YLNPMAAFAAAQMQQ 298
                          +  G+ G   Q        LMA +A+G    L   AA AAA   Q
Sbjct: 342 ---------------LDLGSAGGRFQ--------LMAKLAEGAGIQLPSTAAAAAAAAAQ 378

Query: 299 MAALNMNGLAAAPMTPTSGGSTPPGITA 326
            AAL +NG  A P+    G   P  +TA
Sbjct: 379 AAALQLNG--AVPL----GALNPAALTA 400


>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
          Length = 367

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 55/189 (29%), Positives = 93/189 (49%), Gaps = 14/189 (7%)

Query: 50  DHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESAL 109
           D     L +  +P+N+ + + K LF   G I    +++D+ TG   G  F+ Y +   A 
Sbjct: 35  DDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 94

Query: 110 KAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVR 169
           KA + L+  K      + I+V    S +R  S+ +R     D  L+V  L K  S+ ++ 
Sbjct: 95  KAINTLNGLKL---QTKTIKV----SYARPSSASIR-----DANLYVSGLPKTMSQKEME 142

Query: 170 RLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVK 228
           +LF  +G I    IL     G S+G  F+++    EA+ AI  L+G + + GA+  + VK
Sbjct: 143 QLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPL-GAAEPITVK 201

Query: 229 FADTDKERT 237
           FA+   ++T
Sbjct: 202 FANNPSQKT 210



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 42/151 (27%), Positives = 77/151 (50%), Gaps = 11/151 (7%)

Query: 13  ADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKP 72
           AD A  + NGL     +      +  S   PS+  ++D +   L++  +P+ + +K+++ 
Sbjct: 93  ADKAINTLNGLKLQTKT------IKVSYARPSSASIRDAN---LYVSGLPKTMSQKEMEQ 143

Query: 73  LFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKP 132
           LF ++G+I    +L D+ TG+ +G  F+ + +R  A +A   L+ QK L G   PI VK 
Sbjct: 144 LFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPL-GAAEPITVKF 202

Query: 133 ADSES-RGGSSCLRQPPSQDRKLFVGMLNKQ 162
           A++ S + G + L        + + G L+ Q
Sbjct: 203 ANNPSQKTGQALLTHLYQSSARRYAGPLHHQ 233



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 82/362 (22%), Positives = 127/362 (35%), Gaps = 74/362 (20%)

Query: 154 LFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINAL 212
           L V  L +  ++D+ + LF + G+IE C ++R    G S G  FV YS   +A  AIN L
Sbjct: 41  LIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTL 100

Query: 213 HG----------SQTMPGASSSLVVKFADTDKERTM--RRMQQMAGQMGMFNPMAIPFGA 260
           +G          S   P ++S        +   +TM  + M+Q+  Q G      I    
Sbjct: 101 NGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRI---- 156

Query: 261 YGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGST 320
                  L+ Q    +  V++G        F     +  A   + GL          G  
Sbjct: 157 -------LVDQ----VTGVSRG------VGFIRFDKRIEAEEAIKGL---------NGQK 190

Query: 321 PPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPY--PAQSPTAADPLQQ 378
           P G   P             F   P Q  GQ     ++ +    Y  P    T    L  
Sbjct: 191 PLGAAEPITVK---------FANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDN 241

Query: 379 AYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELM 438
                     P +  A +  I+         +         G  +F+Y+L  E  ++ L 
Sbjct: 242 LLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLW 301

Query: 439 QMFLPFG--------------------FVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKR 478
           Q+F PFG                    FV+  N   A  AI ++NG+++G + L+V  K 
Sbjct: 302 QLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKT 361

Query: 479 PK 480
            K
Sbjct: 362 SK 363



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 30/121 (24%), Positives = 44/121 (36%), Gaps = 21/121 (17%)

Query: 383 VQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMF- 441
           V Q  G        G    A P  P ++           NL + +LPQ     E   +F 
Sbjct: 2   VTQILGAMESQVGGGPAGPALPNGP-LLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFG 60

Query: 442 -------------------LPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDA 482
                              L +GFV++ +P  A  AI  +NG ++  K +KV   RP  A
Sbjct: 61  SIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSA 120

Query: 483 N 483
           +
Sbjct: 121 S 121



 Score = 32.3 bits (72), Expect = 0.99
 Identities = 18/61 (29%), Positives = 30/61 (49%)

Query: 56  LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
           +F+  +    DE  L  LF  FG +  + V++D  T   KG  F+T    + A  A ++L
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345

Query: 116 H 116
           +
Sbjct: 346 N 346


>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
          Length = 360

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 55/189 (29%), Positives = 93/189 (49%), Gaps = 14/189 (7%)

Query: 50  DHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESAL 109
           D     L +  +P+N+ + + K LF   G I    +++D+ TG   G  F+ Y +   A 
Sbjct: 35  DDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 94

Query: 110 KAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVR 169
           KA + L+  K      + I+V    S +R  S+ +R     D  L+V  L K  S+ ++ 
Sbjct: 95  KAINTLNGLKL---QTKTIKV----SYARPSSASIR-----DANLYVSGLPKTMSQKEME 142

Query: 170 RLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVK 228
           +LF  +G I    IL     G S+G  F+++    EA+ AI  L+G + + GA+  + VK
Sbjct: 143 QLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPL-GAAEPITVK 201

Query: 229 FADTDKERT 237
           FA+   ++T
Sbjct: 202 FANNPSQKT 210



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 42/151 (27%), Positives = 77/151 (50%), Gaps = 11/151 (7%)

Query: 13  ADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKP 72
           AD A  + NGL     +      +  S   PS+  ++D +   L++  +P+ + +K+++ 
Sbjct: 93  ADKAINTLNGLKLQTKT------IKVSYARPSSASIRDAN---LYVSGLPKTMSQKEMEQ 143

Query: 73  LFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKP 132
           LF ++G+I    +L D+ TG+ +G  F+ + +R  A +A   L+ QK L G   PI VK 
Sbjct: 144 LFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPL-GAAEPITVKF 202

Query: 133 ADSES-RGGSSCLRQPPSQDRKLFVGMLNKQ 162
           A++ S + G + L        + + G L+ Q
Sbjct: 203 ANNPSQKTGQALLTHLYQSSARRYAGPLHHQ 233



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 85/365 (23%), Positives = 131/365 (35%), Gaps = 87/365 (23%)

Query: 154 LFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINAL 212
           L V  L +  ++D+ + LF + G+IE C ++R    G S G  FV YS   +A  AIN L
Sbjct: 41  LIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTL 100

Query: 213 HG----------SQTMPGASSSLVVKFADTDKERTM--RRMQQMAGQMGMFNPMAIPFGA 260
           +G          S   P ++S        +   +TM  + M+Q+  Q G      I    
Sbjct: 101 NGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRI---- 156

Query: 261 YGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGST 320
                  L+ Q    +  V++G        F     +  A   + GL          G  
Sbjct: 157 -------LVDQ----VTGVSRG------VGFIRFDKRIEAEEAIKGL---------NGQK 190

Query: 321 PPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPY--PAQSPTAA---DP 375
           P G   P             F   P Q  GQ     ++ +    Y  P    T     D 
Sbjct: 191 PLGAAEPITVK---------FANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDN 241

Query: 376 LQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDA 435
           L     GV++++ P A     G            +         G  +F+Y+L  E  ++
Sbjct: 242 LLNMAYGVKRFS-PIAIDGMSGLAG---------VGLSGGAAGAGWCIFVYNLSPEADES 291

Query: 436 ELMQMFLPFG--------------------FVSFDNPASAQTAIQAMNGFQIGMKRLKVQ 475
            L Q+F PFG                    FV+  N   A  AI ++NG+++G + L+V 
Sbjct: 292 VLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVS 351

Query: 476 LKRPK 480
            K  K
Sbjct: 352 FKTSK 356



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 30/121 (24%), Positives = 44/121 (36%), Gaps = 21/121 (17%)

Query: 383 VQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMF- 441
           V Q  G        G    A P  P ++           NL + +LPQ     E   +F 
Sbjct: 2   VTQILGAMESQVGGGPAGPALPNGP-LLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFG 60

Query: 442 -------------------LPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDA 482
                              L +GFV++ +P  A  AI  +NG ++  K +KV   RP  A
Sbjct: 61  SIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSA 120

Query: 483 N 483
           +
Sbjct: 121 S 121



 Score = 32.3 bits (72), Expect = 0.99
 Identities = 18/61 (29%), Positives = 30/61 (49%)

Query: 56  LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
           +F+  +    DE  L  LF  FG +  + V++D  T   KG  F+T    + A  A ++L
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338

Query: 116 H 116
           +
Sbjct: 339 N 339


>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
          Length = 405

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 77/295 (26%), Positives = 131/295 (44%), Gaps = 56/295 (18%)

Query: 49  KDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESA 108
           ++ DA  +F  Q+   +  +DL+  F   GK+ ++ ++ DR +   KG A++ +CE +S 
Sbjct: 127 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 186

Query: 109 LKAQSALHEQKTLPGMNRPIQVKPADSESRGG-SSCLRQPPSQDRKLFVGMLNKQQSEDD 167
             A     ++  L G+   +Q   A+       ++ L++      +L+VG L+   +ED 
Sbjct: 187 PLAIGLTGQR--LLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDM 244

Query: 168 VRRLFEAFGNIEECTILRGPD-GNSKGCAFVKYSSHAEAQAAINALHG------------ 214
           +R +FE FG I+   +++  D G SKG  F+ +S    A+ A+  L+G            
Sbjct: 245 LRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGH 304

Query: 215 -SQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQA 273
            ++ + G +    + F D D+E                    +  G+ G   Q       
Sbjct: 305 VTERLDGGTD---ITFPDGDQE--------------------LDLGSAGGRFQ------- 334

Query: 274 ALMASVAQGG--YLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITA 326
            LMA +A+G    L   AA AAA   Q AAL +NG  A P+    G   P  +TA
Sbjct: 335 -LMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNG--AVPL----GALNPAALTA 382


>gi|93277070 RNA binding motif protein 45 [Homo sapiens]
          Length = 474

 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 57/197 (28%), Positives = 93/197 (47%), Gaps = 21/197 (10%)

Query: 14  DNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPL 73
           D A  S +G G  PG    ++ L   P +            ++F+  I +   E  L+  
Sbjct: 2   DEAGSSASGGGFRPG----VDSLDEPPNS------------RIFL-VISKYTPESVLRER 44

Query: 74  FEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPA 133
           F  FG I ++ V++D+ T   KG AF+ +     A +A   +H Q   P   +PI+V  A
Sbjct: 45  FSPFGDIQDIWVVRDKHTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIA 104

Query: 134 DSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSK 192
            S S G     R    ++      M+ K  +E+D+R  F+ +G+IE C+I++    G SK
Sbjct: 105 QSRSSGSH---RDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESK 161

Query: 193 GCAFVKYSSHAEAQAAI 209
           G  +V+Y   ++A  AI
Sbjct: 162 GLGYVRYLKPSQAAQAI 178



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 63/272 (23%), Positives = 119/272 (43%), Gaps = 42/272 (15%)

Query: 36  LSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHK 95
           ++ S  + S   ++D +  ++F+  IP++  E+DL+  F+ +G I   +++K++ TG  K
Sbjct: 103 IAQSRSSGSHRDVEDEELTRIFV-MIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESK 161

Query: 96  GCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQP-------- 147
           G  ++ Y +   A  AQ+  +  ++   +    + K ++S  +   S +RQ         
Sbjct: 162 GLGYVRYLKPSQA--AQAIENCDRSFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRV 219

Query: 148 ---PSQDRKLFVGM----------LNKQQS--------EDDVRRLFEAFGNIEECTILRG 186
              P + +  F             ++K+ S        E+ +  +F+    +E C + R 
Sbjct: 220 NMFPFEQQSEFSSFDKNDSRGQEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRD 279

Query: 187 PDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERT--MRRM--Q 242
           P  N  G   V+Y + A A  A   LHG Q  PG  + + V F D     T  +R+M  Q
Sbjct: 280 PYSNY-GHGVVQYFNVASAIYAKYKLHGFQYPPG--NRIGVSFIDDGSNATDLLRKMATQ 336

Query: 243 QMAGQMGMF---NPMAIPFGAYGAYAQALMQQ 271
            +A Q+      NP    F  +G  + + + Q
Sbjct: 337 MVAAQLASMVWNNPSQQQFMQFGGSSGSQLPQ 368



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 29/106 (27%), Positives = 55/106 (51%), Gaps = 4/106 (3%)

Query: 138 RGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGN-SKGCAF 196
           R G   L +PP+   ++F+ +++K   E  +R  F  FG+I++  ++R      SKG AF
Sbjct: 14  RPGVDSLDEPPNS--RIFL-VISKYTPESVLRERFSPFGDIQDIWVVRDKHTKESKGIAF 70

Query: 197 VKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQ 242
           VK++  ++A  A+  +HG    P  +  + V  A +    + R ++
Sbjct: 71  VKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVE 116



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 11/104 (10%)

Query: 142 SCLRQPPSQD---RKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVK 198
           SC ++ P++     +LF+         D +  +F  FGN+ E  ++ G     K   + K
Sbjct: 377 SCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVSG-----KNVGYAK 431

Query: 199 YSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQ 242
           Y+    A  AI  LHG + + G    L V  AD+ +E + +R +
Sbjct: 432 YADRISANDAIATLHG-KILNGV--RLKVMLADSPREESNKRQR 472


>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
          Length = 380

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 57/218 (26%), Positives = 105/218 (48%), Gaps = 14/218 (6%)

Query: 25  SSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELT 84
           +S  S G  +   + P    T    D     L +  +P+N+ +++ + LF   G+I    
Sbjct: 17  TSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 76

Query: 85  VLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCL 144
           +++D+ TG   G  F+ Y + + A KA + L+  +      + I+V    S +R  S+ +
Sbjct: 77  LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL---QTKTIKV----SYARPSSASI 129

Query: 145 RQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHA 203
           R     D  L+V  L K  ++ ++ +LF  +G I    IL     G S+G  F+++    
Sbjct: 130 R-----DANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRI 184

Query: 204 EAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRM 241
           EA+ AI  L+G Q   GA+  + VKFA+   +++ + +
Sbjct: 185 EAEEAIKGLNG-QKPSGATEPITVKFANNPSQKSSQAL 221



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 94/400 (23%), Positives = 144/400 (36%), Gaps = 90/400 (22%)

Query: 132 PADSESRGGSSCLRQPPS--------QDRK--LFVGMLNKQQSEDDVRRLFEAFGNIEEC 181
           P  + S G SS  R  PS         D K  L V  L +  ++++ R LF + G IE C
Sbjct: 16  PTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESC 75

Query: 182 TILRGP-DGNSKGCAFVKYSSHAEAQAAINALHG----------SQTMPGASS--SLVVK 228
            ++R    G S G  FV Y    +A+ AIN L+G          S   P ++S     + 
Sbjct: 76  KLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLY 135

Query: 229 FADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPM 288
            +   K  T + ++Q+  Q G      I           L+ Q    +  V++G      
Sbjct: 136 VSGLPKTMTQKELEQLFSQYGRIITSRI-----------LVDQ----VTGVSRG------ 174

Query: 289 AAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQA 348
             F     +  A   + GL          G  P G T P             F   P Q 
Sbjct: 175 VGFIRFDKRIEAEEAIKGL---------NGQKPSGATEPITVK---------FANNPSQK 216

Query: 349 NGQPAAEAVFANGIHPYP------AQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQA 402
           + Q     ++ +    YP      AQ     + L  AY   +  +GP    A   + S  
Sbjct: 217 SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPI 276

Query: 403 FPQPPPMIPQQQREGPEGCN--LFIYHLPQEFGDAELMQMFLPFG--------------- 445
                  +      G  G    +F+Y+L  +  ++ L Q+F PFG               
Sbjct: 277 TIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNK 336

Query: 446 -----FVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 480
                FV+  N   A  AI ++NG+++G + L+V  K  K
Sbjct: 337 CKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 376



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 20/82 (24%)

Query: 422 NLFIYHLPQEFGDAELMQMF--------------------LPFGFVSFDNPASAQTAIQA 461
           NL + +LPQ     E   +F                    L +GFV++ +P  A+ AI  
Sbjct: 47  NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106

Query: 462 MNGFQIGMKRLKVQLKRPKDAN 483
           +NG ++  K +KV   RP  A+
Sbjct: 107 LNGLRLQTKTIKVSYARPSSAS 128



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 18/61 (29%), Positives = 31/61 (50%)

Query: 56  LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
           +F+  +  + DE  L  LF  FG +  + V++D  T   KG  F+T    + A  A ++L
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358

Query: 116 H 116
           +
Sbjct: 359 N 359


>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
          Length = 369

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 57/218 (26%), Positives = 105/218 (48%), Gaps = 14/218 (6%)

Query: 25  SSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELT 84
           +S  S G  +   + P    T    D     L +  +P+N+ +++ + LF   G+I    
Sbjct: 20  TSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 79

Query: 85  VLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCL 144
           +++D+ TG   G  F+ Y + + A KA + L+  +      + I+V    S +R  S+ +
Sbjct: 80  LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL---QTKTIKV----SYARPSSASI 132

Query: 145 RQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHA 203
           R     D  L+V  L K  ++ ++ +LF  +G I    IL     G S+G  F+++    
Sbjct: 133 R-----DANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRI 187

Query: 204 EAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRM 241
           EA+ AI  L+G Q   GA+  + VKFA+   +++ + +
Sbjct: 188 EAEEAIKGLNG-QKPSGATEPITVKFANNPSQKSSQAL 224



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 94/398 (23%), Positives = 145/398 (36%), Gaps = 100/398 (25%)

Query: 132 PADSESRGGSSCLRQPPS--------QDRK--LFVGMLNKQQSEDDVRRLFEAFGNIEEC 181
           P  + S G SS  R  PS         D K  L V  L +  ++++ R LF + G IE C
Sbjct: 19  PTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESC 78

Query: 182 TILRGP-DGNSKGCAFVKYSSHAEAQAAINALHG----------SQTMPGASS--SLVVK 228
            ++R    G S G  FV Y    +A+ AIN L+G          S   P ++S     + 
Sbjct: 79  KLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLY 138

Query: 229 FADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPM 288
            +   K  T + ++Q+  Q G      I           L+ Q    +  V++G      
Sbjct: 139 VSGLPKTMTQKELEQLFSQYGRIITSRI-----------LVDQ----VTGVSRG------ 177

Query: 289 AAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQA 348
             F     +  A   + GL          G  P G T P             F   P Q 
Sbjct: 178 VGFIRFDKRIEAEEAIKGL---------NGQKPSGATEPITVK---------FANNPSQK 219

Query: 349 NGQPAAEAVFANGIHPYP------AQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQA 402
           + Q     ++ +    YP      AQ     + L  AY GV++++ P         +   
Sbjct: 220 SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAY-GVKRFS-PITIDGMTSLVGMN 277

Query: 403 FPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG----------------- 445
            P            G   C +F+Y+L  +  ++ L Q+F PFG                 
Sbjct: 278 IPG---------HTGTGWC-IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCK 327

Query: 446 ---FVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 480
              FV+  N   A  AI ++NG+++G + L+V  K  K
Sbjct: 328 GFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 365



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 20/82 (24%)

Query: 422 NLFIYHLPQEFGDAELMQMF--------------------LPFGFVSFDNPASAQTAIQA 461
           NL + +LPQ     E   +F                    L +GFV++ +P  A+ AI  
Sbjct: 50  NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 109

Query: 462 MNGFQIGMKRLKVQLKRPKDAN 483
           +NG ++  K +KV   RP  A+
Sbjct: 110 LNGLRLQTKTIKVSYARPSSAS 131



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 18/61 (29%), Positives = 31/61 (50%)

Query: 56  LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
           +F+  +  + DE  L  LF  FG +  + V++D  T   KG  F+T    + A  A ++L
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347

Query: 116 H 116
           +
Sbjct: 348 N 348


>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
          Length = 366

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 57/218 (26%), Positives = 105/218 (48%), Gaps = 14/218 (6%)

Query: 25  SSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELT 84
           +S  S G  +   + P    T    D     L +  +P+N+ +++ + LF   G+I    
Sbjct: 17  TSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 76

Query: 85  VLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCL 144
           +++D+ TG   G  F+ Y + + A KA + L+  +      + I+V    S +R  S+ +
Sbjct: 77  LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL---QTKTIKV----SYARPSSASI 129

Query: 145 RQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHA 203
           R     D  L+V  L K  ++ ++ +LF  +G I    IL     G S+G  F+++    
Sbjct: 130 R-----DANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRI 184

Query: 204 EAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRM 241
           EA+ AI  L+G Q   GA+  + VKFA+   +++ + +
Sbjct: 185 EAEEAIKGLNG-QKPSGATEPITVKFANNPSQKSSQAL 221



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 95/412 (23%), Positives = 150/412 (36%), Gaps = 100/412 (24%)

Query: 118 QKTLPGMNRPIQVKPADSESRGGSSCLRQPPS--------QDRK--LFVGMLNKQQSEDD 167
           ++ +  M   +   P  + S G SS  R  PS         D K  L V  L +  ++++
Sbjct: 2   EQIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEE 61

Query: 168 VRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALHG----------SQ 216
            R LF + G IE C ++R    G S G  FV Y    +A+ AIN L+G          S 
Sbjct: 62  FRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSY 121

Query: 217 TMPGASS--SLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAA 274
             P ++S     +  +   K  T + ++Q+  Q G      I           L+ Q   
Sbjct: 122 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI-----------LVDQ--- 167

Query: 275 LMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPS 334
            +  V++G        F     +  A   + GL          G  P G T P       
Sbjct: 168 -VTGVSRG------VGFIRFDKRIEAEEAIKGL---------NGQKPSGATEPITVK--- 208

Query: 335 PIGVNGFTGLPPQANGQPAAEAVFANGIHPYP------AQSPTAADPLQQAYAGVQQYAG 388
                 F   P Q + Q     ++ +    YP      AQ     + L  AY GV++++ 
Sbjct: 209 ------FANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAY-GVKRFS- 260

Query: 389 PAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG--- 445
           P         +    P            G   C +F+Y+L  +  ++ L Q+F PFG   
Sbjct: 261 PITIDGMTSLVGMNIPG---------HTGTGWC-IFVYNLSPDSDESVLWQLFGPFGAVN 310

Query: 446 -----------------FVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 480
                            FV+  N   A  AI ++NG+++G + L+V  K  K
Sbjct: 311 NVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 362



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 20/82 (24%)

Query: 422 NLFIYHLPQEFGDAELMQMF--------------------LPFGFVSFDNPASAQTAIQA 461
           NL + +LPQ     E   +F                    L +GFV++ +P  A+ AI  
Sbjct: 47  NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106

Query: 462 MNGFQIGMKRLKVQLKRPKDAN 483
           +NG ++  K +KV   RP  A+
Sbjct: 107 LNGLRLQTKTIKVSYARPSSAS 128



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 18/61 (29%), Positives = 31/61 (50%)

Query: 56  LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
           +F+  +  + DE  L  LF  FG +  + V++D  T   KG  F+T    + A  A ++L
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344

Query: 116 H 116
           +
Sbjct: 345 N 345


>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
          Length = 383

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 57/218 (26%), Positives = 105/218 (48%), Gaps = 14/218 (6%)

Query: 25  SSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELT 84
           +S  S G  +   + P    T    D     L +  +P+N+ +++ + LF   G+I    
Sbjct: 34  TSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 93

Query: 85  VLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCL 144
           +++D+ TG   G  F+ Y + + A KA + L+  +      + I+V    S +R  S+ +
Sbjct: 94  LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL---QTKTIKV----SYARPSSASI 146

Query: 145 RQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHA 203
           R     D  L+V  L K  ++ ++ +LF  +G I    IL     G S+G  F+++    
Sbjct: 147 R-----DANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRI 201

Query: 204 EAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRM 241
           EA+ AI  L+G Q   GA+  + VKFA+   +++ + +
Sbjct: 202 EAEEAIKGLNG-QKPSGATEPITVKFANNPSQKSSQAL 238



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 94/398 (23%), Positives = 145/398 (36%), Gaps = 100/398 (25%)

Query: 132 PADSESRGGSSCLRQPPS--------QDRK--LFVGMLNKQQSEDDVRRLFEAFGNIEEC 181
           P  + S G SS  R  PS         D K  L V  L +  ++++ R LF + G IE C
Sbjct: 33  PTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESC 92

Query: 182 TILRGP-DGNSKGCAFVKYSSHAEAQAAINALHG----------SQTMPGASS--SLVVK 228
            ++R    G S G  FV Y    +A+ AIN L+G          S   P ++S     + 
Sbjct: 93  KLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLY 152

Query: 229 FADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPM 288
            +   K  T + ++Q+  Q G      I           L+ Q    +  V++G      
Sbjct: 153 VSGLPKTMTQKELEQLFSQYGRIITSRI-----------LVDQ----VTGVSRG------ 191

Query: 289 AAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQA 348
             F     +  A   + GL          G  P G T P             F   P Q 
Sbjct: 192 VGFIRFDKRIEAEEAIKGL---------NGQKPSGATEPITVK---------FANNPSQK 233

Query: 349 NGQPAAEAVFANGIHPYP------AQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQA 402
           + Q     ++ +    YP      AQ     + L  AY GV++++ P         +   
Sbjct: 234 SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAY-GVKRFS-PITIDGMTSLVGMN 291

Query: 403 FPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG----------------- 445
            P            G   C +F+Y+L  +  ++ L Q+F PFG                 
Sbjct: 292 IPG---------HTGTGWC-IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCK 341

Query: 446 ---FVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 480
              FV+  N   A  AI ++NG+++G + L+V  K  K
Sbjct: 342 GFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 379



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 20/82 (24%)

Query: 422 NLFIYHLPQEFGDAELMQMF--------------------LPFGFVSFDNPASAQTAIQA 461
           NL + +LPQ     E   +F                    L +GFV++ +P  A+ AI  
Sbjct: 64  NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123

Query: 462 MNGFQIGMKRLKVQLKRPKDAN 483
           +NG ++  K +KV   RP  A+
Sbjct: 124 LNGLRLQTKTIKVSYARPSSAS 145



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 18/61 (29%), Positives = 31/61 (50%)

Query: 56  LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
           +F+  +  + DE  L  LF  FG +  + V++D  T   KG  F+T    + A  A ++L
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361

Query: 116 H 116
           +
Sbjct: 362 N 362


>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
          Length = 366

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 57/218 (26%), Positives = 105/218 (48%), Gaps = 14/218 (6%)

Query: 25  SSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELT 84
           +S  S G  +   + P    T    D     L +  +P+N+ +++ + LF   G+I    
Sbjct: 17  TSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 76

Query: 85  VLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCL 144
           +++D+ TG   G  F+ Y + + A KA + L+  +      + I+V    S +R  S+ +
Sbjct: 77  LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL---QTKTIKV----SYARPSSASI 129

Query: 145 RQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHA 203
           R     D  L+V  L K  ++ ++ +LF  +G I    IL     G S+G  F+++    
Sbjct: 130 R-----DANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRI 184

Query: 204 EAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRM 241
           EA+ AI  L+G Q   GA+  + VKFA+   +++ + +
Sbjct: 185 EAEEAIKGLNG-QKPSGATEPITVKFANNPSQKSSQAL 221



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 94/398 (23%), Positives = 145/398 (36%), Gaps = 100/398 (25%)

Query: 132 PADSESRGGSSCLRQPPS--------QDRK--LFVGMLNKQQSEDDVRRLFEAFGNIEEC 181
           P  + S G SS  R  PS         D K  L V  L +  ++++ R LF + G IE C
Sbjct: 16  PTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESC 75

Query: 182 TILRGP-DGNSKGCAFVKYSSHAEAQAAINALHG----------SQTMPGASS--SLVVK 228
            ++R    G S G  FV Y    +A+ AIN L+G          S   P ++S     + 
Sbjct: 76  KLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLY 135

Query: 229 FADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPM 288
            +   K  T + ++Q+  Q G      I           L+ Q    +  V++G      
Sbjct: 136 VSGLPKTMTQKELEQLFSQYGRIITSRI-----------LVDQ----VTGVSRG------ 174

Query: 289 AAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQA 348
             F     +  A   + GL          G  P G T P             F   P Q 
Sbjct: 175 VGFIRFDKRIEAEEAIKGL---------NGQKPSGATEPITVK---------FANNPSQK 216

Query: 349 NGQPAAEAVFANGIHPYP------AQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQA 402
           + Q     ++ +    YP      AQ     + L  AY GV++++ P         +   
Sbjct: 217 SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAY-GVKRFS-PITIDGMTSLVGMN 274

Query: 403 FPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG----------------- 445
            P            G   C +F+Y+L  +  ++ L Q+F PFG                 
Sbjct: 275 IPG---------HTGTGWC-IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCK 324

Query: 446 ---FVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPK 480
              FV+  N   A  AI ++NG+++G + L+V  K  K
Sbjct: 325 GFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 362



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 20/82 (24%)

Query: 422 NLFIYHLPQEFGDAELMQMF--------------------LPFGFVSFDNPASAQTAIQA 461
           NL + +LPQ     E   +F                    L +GFV++ +P  A+ AI  
Sbjct: 47  NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106

Query: 462 MNGFQIGMKRLKVQLKRPKDAN 483
           +NG ++  K +KV   RP  A+
Sbjct: 107 LNGLRLQTKTIKVSYARPSSAS 128



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 18/61 (29%), Positives = 31/61 (50%)

Query: 56  LFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSAL 115
           +F+  +  + DE  L  LF  FG +  + V++D  T   KG  F+T    + A  A ++L
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344

Query: 116 H 116
           +
Sbjct: 345 N 345


>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
           sapiens]
          Length = 516

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 76/296 (25%), Positives = 126/296 (42%), Gaps = 21/296 (7%)

Query: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
           ++++G I   L E  ++  F  FG I  + +  D  T  HKG AF+ Y   E+A   Q A
Sbjct: 87  RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAA---QLA 143

Query: 115 LHEQKTLPGMNRPIQV-KPAD-SESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLF 172
           L +  ++    R I+V +P++  +++     L +      +++V  +++  S+DD++ +F
Sbjct: 144 LEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVF 203

Query: 173 EAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFAD 231
           EAFG I+ CT+ R P  G  KG  F++Y     +Q A+++++           L  ++  
Sbjct: 204 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN--------LFDLGGQYLR 255

Query: 232 TDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAF 291
             K  T           G   P A       A A A +  Q A+  +   G    P    
Sbjct: 256 VGKAVTPPMPLLTPATPGGLPPAA---AVAAAAATAKITAQEAVAGAAVLGTLGTPGLVS 312

Query: 292 AAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVP-SIPSPIGVNGFTGLPP 346
            A  + Q        + AA       G TP     P +P +IPS   VN     PP
Sbjct: 313 PALTLAQPLGTLPQAVMAAQAPGVITGVTP---ARPPIPVTIPSVGVVNPILASPP 365



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 20/86 (23%)

Query: 409 MIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG--------------------FVS 448
           M  Q+QR     C +++  +  E G+  + Q F PFG                    FV 
Sbjct: 74  MAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVE 133

Query: 449 FDNPASAQTAIQAMNGFQIGMKRLKV 474
           ++ P +AQ A++ MN   +G + +KV
Sbjct: 134 YEVPEAAQLALEQMNSVMLGGRNIKV 159



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 20/90 (22%), Positives = 38/90 (42%), Gaps = 20/90 (22%)

Query: 405 QPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG------------------- 445
           Q  P+I Q   E      +++  + Q+  D ++  +F  FG                   
Sbjct: 167 QAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGY 226

Query: 446 -FVSFDNPASAQTAIQAMNGFQIGMKRLKV 474
            F+ ++   S+Q A+ +MN F +G + L+V
Sbjct: 227 GFIEYEKAQSSQDAVSSMNLFDLGGQYLRV 256


>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
           sapiens]
          Length = 542

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 76/296 (25%), Positives = 126/296 (42%), Gaps = 21/296 (7%)

Query: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
           ++++G I   L E  ++  F  FG I  + +  D  T  HKG AF+ Y   E+A   Q A
Sbjct: 113 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAA---QLA 169

Query: 115 LHEQKTLPGMNRPIQV-KPAD-SESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLF 172
           L +  ++    R I+V +P++  +++     L +      +++V  +++  S+DD++ +F
Sbjct: 170 LEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVF 229

Query: 173 EAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFAD 231
           EAFG I+ CT+ R P  G  KG  F++Y     +Q A+++++           L  ++  
Sbjct: 230 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN--------LFDLGGQYLR 281

Query: 232 TDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAF 291
             K  T           G   P A       A A A +  Q A+  +   G    P    
Sbjct: 282 VGKAVTPPMPLLTPATPGGLPPAA---AVAAAAATAKITAQEAVAGAAVLGTLGTPGLVS 338

Query: 292 AAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVP-SIPSPIGVNGFTGLPP 346
            A  + Q        + AA       G TP     P +P +IPS   VN     PP
Sbjct: 339 PALTLAQPLGTLPQAVMAAQAPGVITGVTP---ARPPIPVTIPSVGVVNPILASPP 391



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 49/205 (23%), Positives = 77/205 (37%), Gaps = 57/205 (27%)

Query: 301 ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQA-------NGQPA 353
           AL +NG          GG + P   A  V +        G    PPQ        NGQ  
Sbjct: 7   ALQVNG--------QQGGGSEPAAAAAVVAA--------GDKWKPPQGTDSIKMENGQST 50

Query: 354 AEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPP----PM 409
           A  +        P  +P   + LQ+A    ++YA   +  +   + + A  Q       M
Sbjct: 51  AAKL------GLPPLTPEQQEALQKA----KKYAMEQSIKSVLVKQTIAHQQQQLTNLQM 100

Query: 410 IPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG--------------------FVSF 449
             Q+QR     C +++  +  E G+  + Q F PFG                    FV +
Sbjct: 101 AAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEY 160

Query: 450 DNPASAQTAIQAMNGFQIGMKRLKV 474
           + P +AQ A++ MN   +G + +KV
Sbjct: 161 EVPEAAQLALEQMNSVMLGGRNIKV 185



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 20/90 (22%), Positives = 38/90 (42%), Gaps = 20/90 (22%)

Query: 405 QPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG------------------- 445
           Q  P+I Q   E      +++  + Q+  D ++  +F  FG                   
Sbjct: 193 QAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGY 252

Query: 446 -FVSFDNPASAQTAIQAMNGFQIGMKRLKV 474
            F+ ++   S+Q A+ +MN F +G + L+V
Sbjct: 253 GFIEYEKAQSSQDAVSSMNLFDLGGQYLRV 282


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,459,230
Number of Sequences: 37866
Number of extensions: 1071405
Number of successful extensions: 7927
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 217
Number of HSP's successfully gapped in prelim test: 475
Number of HSP's that attempted gapping in prelim test: 5755
Number of HSP's gapped (non-prelim): 2159
length of query: 486
length of database: 18,247,518
effective HSP length: 106
effective length of query: 380
effective length of database: 14,233,722
effective search space: 5408814360
effective search space used: 5408814360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.