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Search of human proteins with 4504849
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504849 potassium channel, subfamily K, member 3 [Homo
sapiens]
(394 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens] 791 0.0
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens] 428 e-120
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens] 330 1e-90
gi|14589851 potassium channel, subfamily K, member 2 isoform b [... 135 5e-32
gi|126365795 potassium channel, subfamily K, member 2 isoform c ... 135 5e-32
gi|62912487 potassium channel, subfamily K, member 2 isoform a [... 135 5e-32
gi|205360983 potassium channel, subfamily K, member 16 isoform 3... 135 5e-32
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ... 135 5e-32
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi... 134 2e-31
gi|205360973 potassium channel, subfamily K, member 16 isoform 4... 131 1e-30
gi|205360971 potassium channel, subfamily K, member 16 isoform 1... 131 1e-30
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ... 130 2e-30
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ... 130 2e-30
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ... 130 2e-30
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens] 120 3e-27
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 120 3e-27
gi|15718767 TRAAK [Homo sapiens] 119 5e-27
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi... 113 3e-25
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ... 112 8e-25
gi|205361107 potassium channel, subfamily K, member 17 isoform 2... 110 3e-24
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens] 106 4e-23
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H... 84 3e-16
gi|16118231 potassium channel, subfamily K, member 7 isoform A [... 84 3e-16
gi|16118235 potassium channel, subfamily K, member 7 isoform B [... 84 3e-16
gi|16118233 potassium channel, subfamily K, member 7 isoform B [... 84 3e-16
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi... 74 2e-13
gi|22024390 potassium voltage-gated channel, subfamily H, member... 42 0.001
gi|27886648 potassium voltage-gated channel, subfamily H, member... 42 0.001
gi|27886646 potassium voltage-gated channel, subfamily H, member... 42 0.001
gi|4504831 potassium voltage-gated channel, subfamily H, member ... 42 0.001
>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
Length = 394
Score = 791 bits (2042), Expect = 0.0
Identities = 394/394 (100%), Positives = 394/394 (100%)
Query: 1 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE 60
MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE
Sbjct: 1 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE 60
Query: 61 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120
ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL
Sbjct: 61 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120
Query: 121 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 180
TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH
Sbjct: 121 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 180
Query: 181 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN 240
YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN
Sbjct: 181 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN 240
Query: 241 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY 300
LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY
Sbjct: 241 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY 300
Query: 301 AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRR 360
AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRR
Sbjct: 301 AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRR 360
Query: 361 CLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV 394
CLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV
Sbjct: 361 CLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV 394
>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
Length = 374
Score = 428 bits (1101), Expect = e-120
Identities = 231/394 (58%), Positives = 275/394 (69%), Gaps = 20/394 (5%)
Query: 1 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE 60
MKRQNVRTL+LIVCTFTYLLVGAAVFDALES+ E+ E ++L+ + ++ +YN+S Y
Sbjct: 1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR 60
Query: 61 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120
+LE V+L+ +PH+AGVQW+FAGSFYFAITVITTIGYGHAAP TD GK FCMFYA+LGIPL
Sbjct: 61 QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 120
Query: 121 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 180
TLVMFQSLGER+NT VRYLL R KK GMR DVSM NMV +GFFSC+ TLCIGAAAFS
Sbjct: 121 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 180
Query: 181 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN 240
E W+FF AYYYCFITLTTIGFGDYVALQ ALQ +P YVAFSF+YIL GLTVIGAFLN
Sbjct: 181 CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN 240
Query: 241 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY 300
LVVLRF+TMN+EDE+RDAE RA L G H + +
Sbjct: 241 LVVLRFLTMNSEDERRDAEERASLA------GNRNSMVIHIPEEPRPSRP-------RYK 287
Query: 301 AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRR 360
A+V QS+CSC Y+S++ Y + P++ ++ HS S + +
Sbjct: 288 ADVPDLQSVCSCTCYRSQD---YGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKN 344
Query: 361 CLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV 394
L S ISS+S GLHS + + LMKRR SV
Sbjct: 345 SLFP----SPISSISPGLHSFTDHQRLMKRRKSV 374
>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
Length = 330
Score = 330 bits (846), Expect = 1e-90
Identities = 167/258 (64%), Positives = 199/258 (77%)
Query: 1 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE 60
M+R +VR L++CT YLLVGAAVFDALESE E ++ L ++ LR ++ S Y
Sbjct: 1 MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYR 60
Query: 61 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120
ELER+ L+ +PH+AG QW+F GSFYFAITVITTIGYGHAAP TD GKVFCMFYALLGIPL
Sbjct: 61 ELERLALQAEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
Query: 121 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 180
TLV FQSLGER+N +VR LL AK LG+R VS N+V+ G +C +TL +GA AFSH
Sbjct: 121 TLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSH 180
Query: 181 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN 240
+E WTFF AYYYCFITLTTIGFGD+VALQ +ALQ + YVAFSF+YIL GLTVIGAFLN
Sbjct: 181 FEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLN 240
Query: 241 LVVLRFMTMNAEDEKRDA 258
LVVLRF+ +A+ +R A
Sbjct: 241 LVVLRFLVASADWPERAA 258
>gi|14589851 potassium channel, subfamily K, member 2 isoform b
[Homo sapiens]
Length = 411
Score = 135 bits (341), Expect = 5e-32
Identities = 85/277 (30%), Positives = 146/277 (52%), Gaps = 21/277 (7%)
Query: 1 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE 60
MK + V T+ L+V YL++GA VF ALE E+ +R + +++Q ++++
Sbjct: 42 MKWKTVSTIFLVVVL--YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNS--T 97
Query: 61 ELERVVLRLKPH-KAGV-----------QWRFAGSFYFAITVITTIGYGHAAPSTDGGKV 108
EL+ ++ ++ AG+ W SF+FA TVITTIG+G+ +P T+GGK+
Sbjct: 98 ELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKI 157
Query: 109 FCMFYALLGIPLTLVMFQSLGERINTLVRYLLHRAKKGL---GMRRADVSMANMVLIGFF 165
FC+ YALLGIPL + +G+++ T+ + + + + + + + + ++ F
Sbjct: 158 FCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILF 217
Query: 166 SCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSF 225
C+ + + A F H E W+ A Y+ ITLTTIGFGDYVA D ++ Y +
Sbjct: 218 GCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSD--IEYLDFYKPVVW 275
Query: 226 VYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRA 262
+IL GL A L+++ ++ + ++ E RA
Sbjct: 276 FWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRA 312
>gi|126365795 potassium channel, subfamily K, member 2 isoform c
[Homo sapiens]
Length = 426
Score = 135 bits (341), Expect = 5e-32
Identities = 85/277 (30%), Positives = 146/277 (52%), Gaps = 21/277 (7%)
Query: 1 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE 60
MK + V T+ L+V YL++GA VF ALE E+ +R + +++Q ++++
Sbjct: 57 MKWKTVSTIFLVVVL--YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNS--T 112
Query: 61 ELERVVLRLKPH-KAGV-----------QWRFAGSFYFAITVITTIGYGHAAPSTDGGKV 108
EL+ ++ ++ AG+ W SF+FA TVITTIG+G+ +P T+GGK+
Sbjct: 113 ELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKI 172
Query: 109 FCMFYALLGIPLTLVMFQSLGERINTLVRYLLHRAKKGL---GMRRADVSMANMVLIGFF 165
FC+ YALLGIPL + +G+++ T+ + + + + + + + + ++ F
Sbjct: 173 FCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILF 232
Query: 166 SCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSF 225
C+ + + A F H E W+ A Y+ ITLTTIGFGDYVA D ++ Y +
Sbjct: 233 GCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSD--IEYLDFYKPVVW 290
Query: 226 VYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRA 262
+IL GL A L+++ ++ + ++ E RA
Sbjct: 291 FWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRA 327
>gi|62912487 potassium channel, subfamily K, member 2 isoform a
[Homo sapiens]
Length = 422
Score = 135 bits (341), Expect = 5e-32
Identities = 85/277 (30%), Positives = 146/277 (52%), Gaps = 21/277 (7%)
Query: 1 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE 60
MK + V T+ L+V YL++GA VF ALE E+ +R + +++Q ++++
Sbjct: 53 MKWKTVSTIFLVVVL--YLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNS--T 108
Query: 61 ELERVVLRLKPH-KAGV-----------QWRFAGSFYFAITVITTIGYGHAAPSTDGGKV 108
EL+ ++ ++ AG+ W SF+FA TVITTIG+G+ +P T+GGK+
Sbjct: 109 ELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKI 168
Query: 109 FCMFYALLGIPLTLVMFQSLGERINTLVRYLLHRAKKGL---GMRRADVSMANMVLIGFF 165
FC+ YALLGIPL + +G+++ T+ + + + + + + + + ++ F
Sbjct: 169 FCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILF 228
Query: 166 SCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSF 225
C+ + + A F H E W+ A Y+ ITLTTIGFGDYVA D ++ Y +
Sbjct: 229 GCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSD--IEYLDFYKPVVW 286
Query: 226 VYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRA 262
+IL GL A L+++ ++ + ++ E RA
Sbjct: 287 FWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRA 323
>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
[Homo sapiens]
Length = 294
Score = 135 bits (341), Expect = 5e-32
Identities = 90/248 (36%), Positives = 126/248 (50%), Gaps = 20/248 (8%)
Query: 7 RTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYN-LSQGGYEELERV 65
R L L++ YLL+GA +F LE + E R + +L + Y L Q E+ +V
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
Query: 66 VLR-----LKPHKAGVQ---WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLG 117
++ + P W F SF+FA TV+TTIGYG+ APST+ G+VFC+FYALLG
Sbjct: 73 IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 118 IPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVL-IGFFSCISTLCI--- 173
IPL ++ LG + H A R S VL + F + TL I
Sbjct: 133 IPLNVIFLNHLGTGLRA------HLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
Query: 174 GAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLT 233
FSH E W+F + +Y+ FITL+TIGFGDYV + D + Y + + ++IL GL
Sbjct: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWILLGLA 245
Query: 234 VIGAFLNL 241
+ L L
Sbjct: 246 WLALILPL 253
>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
[Homo sapiens]
Length = 309
Score = 135 bits (341), Expect = 5e-32
Identities = 90/248 (36%), Positives = 126/248 (50%), Gaps = 20/248 (8%)
Query: 7 RTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYN-LSQGGYEELERV 65
R L L++ YLL+GA +F LE + E R + +L + Y L Q E+ +V
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
Query: 66 VLR-----LKPHKAGVQ---WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLG 117
++ + P W F SF+FA TV+TTIGYG+ APST+ G+VFC+FYALLG
Sbjct: 73 IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 118 IPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVL-IGFFSCISTLCI--- 173
IPL ++ LG + H A R S VL + F + TL I
Sbjct: 133 IPLNVIFLNHLGTGLRA------HLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
Query: 174 GAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLT 233
FSH E W+F + +Y+ FITL+TIGFGDYV + D + Y + + ++IL GL
Sbjct: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWILLGLA 245
Query: 234 VIGAFLNL 241
+ L L
Sbjct: 246 WLALILPL 253
>gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
Length = 408
Score = 134 bits (336), Expect = 2e-31
Identities = 88/270 (32%), Positives = 135/270 (50%), Gaps = 31/270 (11%)
Query: 1 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGG-- 58
+ N R L L YLL GAAVF ALE E +QR E R +NLS+
Sbjct: 13 LNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNLSRDELR 72
Query: 59 -----YEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFY 113
YEE R +R+ + +W F G+FYF TV++TIG+G P+T GGK+F +FY
Sbjct: 73 GFLRHYEEATRAGIRVDNVRP--RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFY 130
Query: 114 ALLGIPLTLVMFQSLGERINTLVRYLL---------------HRAKKGLGMRRAD----- 153
L+G T++ F ER+ T++ Y++ + K G D
Sbjct: 131 GLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGW 190
Query: 154 -VSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQ 212
S+ ++LI + I C +A ++ E W++F + Y+CF+ +TIGFGD V+ Q +
Sbjct: 191 KPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQ-NA 249
Query: 213 ALQTQPQYVAFSFVYILTGLTVIGAFLNLV 242
++Q Y +FV+IL G+ I + N++
Sbjct: 250 HYESQGLYRFANFVFILMGVCCIYSLFNVI 279
>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
[Homo sapiens]
Length = 262
Score = 131 bits (329), Expect = 1e-30
Identities = 82/213 (38%), Positives = 111/213 (52%), Gaps = 19/213 (8%)
Query: 7 RTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYN-LSQGGYEELERV 65
R L L++ YLL+GA +F LE + E R + +L + Y L Q E+ +V
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
Query: 66 VLR-----LKPHKAGVQ---WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLG 117
++ + P W F SF+FA TV+TTIGYG+ APST+ G+VFC+FYALLG
Sbjct: 73 IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 118 IPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVL-IGFFSCISTLCI--- 173
IPL ++ LG + H A R S VL + F + TL I
Sbjct: 133 IPLNVIFLNHLGTGLRA------HLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
Query: 174 GAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYV 206
FSH E W+F + +Y+ FITL+TIGFGDYV
Sbjct: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV 219
>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
[Homo sapiens]
Length = 322
Score = 131 bits (329), Expect = 1e-30
Identities = 82/213 (38%), Positives = 111/213 (52%), Gaps = 19/213 (8%)
Query: 7 RTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYN-LSQGGYEELERV 65
R L L++ YLL+GA +F LE + E R + +L + Y L Q E+ +V
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
Query: 66 VLR-----LKPHKAGVQ---WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLG 117
++ + P W F SF+FA TV+TTIGYG+ APST+ G+VFC+FYALLG
Sbjct: 73 IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 118 IPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVL-IGFFSCISTLCI--- 173
IPL ++ LG + H A R S VL + F + TL I
Sbjct: 133 IPLNVIFLNHLGTGLRA------HLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
Query: 174 GAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYV 206
FSH E W+F + +Y+ FITL+TIGFGDYV
Sbjct: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV 219
>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
[Homo sapiens]
Length = 543
Score = 130 bits (328), Expect = 2e-30
Identities = 85/264 (32%), Positives = 137/264 (51%), Gaps = 22/264 (8%)
Query: 9 LALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQE-LRARYNLSQGGYEELERVVL 67
+A+ V YL+ G VF ALE E ++ + L + E LR +S +ELE ++
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSP---QELETLIQ 134
Query: 68 R-LKPHKAGVQ-----------WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYAL 115
L AGV W +F+FA TVITTIGYG+ APST+GGK+FC+ YA+
Sbjct: 135 HALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAI 194
Query: 116 LGIPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRAD---VSMANMVLIGFFSCISTLC 172
GIPL + +G+++ T+ + R +K ++ + + + +L CI +
Sbjct: 195 FGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVT 254
Query: 173 IGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGL 232
I A F + E WT ++ Y+ +TLTT+GFGD+VA + + + Y + +IL GL
Sbjct: 255 IPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVA-GGNAGINYREWYKPLVWFWILVGL 313
Query: 233 TVIGAFLNLV--VLRFMTMNAEDE 254
A L+++ LR ++ ++E
Sbjct: 314 AYFAAVLSMIGDWLRVLSKKTKEE 337
>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
[Homo sapiens]
Length = 543
Score = 130 bits (328), Expect = 2e-30
Identities = 85/264 (32%), Positives = 137/264 (51%), Gaps = 22/264 (8%)
Query: 9 LALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQE-LRARYNLSQGGYEELERVVL 67
+A+ V YL+ G VF ALE E ++ + L + E LR +S +ELE ++
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSP---QELETLIQ 134
Query: 68 R-LKPHKAGVQ-----------WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYAL 115
L AGV W +F+FA TVITTIGYG+ APST+GGK+FC+ YA+
Sbjct: 135 HALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAI 194
Query: 116 LGIPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRAD---VSMANMVLIGFFSCISTLC 172
GIPL + +G+++ T+ + R +K ++ + + + +L CI +
Sbjct: 195 FGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVT 254
Query: 173 IGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGL 232
I A F + E WT ++ Y+ +TLTT+GFGD+VA + + + Y + +IL GL
Sbjct: 255 IPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVA-GGNAGINYREWYKPLVWFWILVGL 313
Query: 233 TVIGAFLNLV--VLRFMTMNAEDE 254
A L+++ LR ++ ++E
Sbjct: 314 AYFAAVLSMIGDWLRVLSKKTKEE 337
>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
[Homo sapiens]
Length = 538
Score = 130 bits (328), Expect = 2e-30
Identities = 85/264 (32%), Positives = 137/264 (51%), Gaps = 22/264 (8%)
Query: 9 LALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQE-LRARYNLSQGGYEELERVVL 67
+A+ V YL+ G VF ALE E ++ + L + E LR +S +ELE ++
Sbjct: 73 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSP---QELETLIQ 129
Query: 68 R-LKPHKAGVQ-----------WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYAL 115
L AGV W +F+FA TVITTIGYG+ APST+GGK+FC+ YA+
Sbjct: 130 HALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAI 189
Query: 116 LGIPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRAD---VSMANMVLIGFFSCISTLC 172
GIPL + +G+++ T+ + R +K ++ + + + +L CI +
Sbjct: 190 FGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVT 249
Query: 173 IGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGL 232
I A F + E WT ++ Y+ +TLTT+GFGD+VA + + + Y + +IL GL
Sbjct: 250 IPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVA-GGNAGINYREWYKPLVWFWILVGL 308
Query: 233 TVIGAFLNLV--VLRFMTMNAEDE 254
A L+++ LR ++ ++E
Sbjct: 309 AYFAAVLSMIGDWLRVLSKKTKEE 332
>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
Length = 499
Score = 120 bits (300), Expect = 3e-27
Identities = 82/252 (32%), Positives = 131/252 (51%), Gaps = 20/252 (7%)
Query: 18 YLLVGAAVFDALESEPELIERQRLELRQQE--LRARYNLSQGGYEELERVV-------LR 68
YL +GAA+F+ LE EP E ++ Q+ L+ L Q G +++ VV +
Sbjct: 15 YLAIGAAIFEVLE-EPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQGVA 73
Query: 69 LKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSL 128
+ ++ W + + FA TVITTIGYG+ AP T G++FC+FY L G+PL L +L
Sbjct: 74 ITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISAL 133
Query: 129 GE----RINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHW 184
G+ R L ++L K+G+ +R+A ++ + ++ + + L I F E W
Sbjct: 134 GKFFGGRAKRLGQFL---TKRGVSLRKAQITCTVIFIV--WGVLVHLVIPPFVFMVTEGW 188
Query: 185 TFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVL 244
+ + YY FIT++TIGFGD+VA A Y F ++I GL + F+N V
Sbjct: 189 NYIEGLYYSFITISTIGFGDFVAGVNPSA-NYHALYRYFVELWIYLGLAWLSLFVNWKVS 247
Query: 245 RFMTMNAEDEKR 256
F+ ++ +KR
Sbjct: 248 MFVEVHKAIKKR 259
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 120 bits (300), Expect = 3e-27
Identities = 75/208 (36%), Positives = 116/208 (55%), Gaps = 13/208 (6%)
Query: 11 LIVCTFTYLLVGAAVFDALESEPELIERQRL-ELRQQELRARYNLSQGGYEELERVVLRL 69
L++ YL+ GA VF ++E E + RQ L +L+++ L LS+ E+ VL
Sbjct: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
Query: 70 KPHKAGV--------QWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLT 121
+ V W F + +FA TV++T GYGH P +DGGK FC+ Y+++GIP T
Sbjct: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
Query: 122 LVMFQSLGERINTLV--RYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFS 179
L+ ++ +RI V R +L+ + G + V++ + VL+GF + I AA FS
Sbjct: 146 LLFLTAVVQRITVHVTRRPVLYFHIR-WGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFS 204
Query: 180 HYE-HWTFFQAYYYCFITLTTIGFGDYV 206
E W F +++Y+CFI+L+TIG GDYV
Sbjct: 205 VLEDDWNFLESFYFCFISLSTIGLGDYV 232
Score = 32.0 bits (71), Expect = 1.00
Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 16/75 (21%)
Query: 78 WRFAGSFYFAITVITTIGYGHAAPSTDGG-------KVFCMFYALLGIPLTLVMFQSLGE 130
W F SFYF ++TIG G P K+ Y LLG+ LV+ ++ E
Sbjct: 210 WNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFCE 269
Query: 131 RINTLVRYLLHRAKK 145
LH KK
Sbjct: 270 ---------LHELKK 275
>gi|15718767 TRAAK [Homo sapiens]
Length = 393
Score = 119 bits (298), Expect = 5e-27
Identities = 88/269 (32%), Positives = 131/269 (48%), Gaps = 44/269 (16%)
Query: 9 LALIVCTFTYLLVGAAVFDALESEPELIERQRL-ELRQQELRARYNLSQ----------- 56
LAL+ YL+ GA VF ALE E ++ L E+R++ LRA +S
Sbjct: 7 LALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGLLIKEVA 66
Query: 57 ---GGYEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFY 113
GG + E H A W +F+F+ T+ITTIGYG+ A TD G++FC+FY
Sbjct: 67 DALGGGADPETNSTSNSSHSA---WDLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIFY 123
Query: 114 ALLGIPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRAD----------VSMANMVLIG 163
AL+GIPL ++ +G+R+ + +R+ G+G A V + + +L
Sbjct: 124 ALVGIPLFGILLAGVGDRLGSSLRH-------GIGHIEAIFLKWHVPPELVRVLSAMLFL 176
Query: 164 FFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAF 223
C+ + F + E W+ +A Y+ +TLTT+GFGDYVA + Q P Y
Sbjct: 177 LIGCLLFVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGADPR--QDSPAYQPL 234
Query: 224 SFVYILTG-------LTVIGAFLNLVVLR 245
+ +IL G LT IG +L +V R
Sbjct: 235 VWFWILLGLAYFASVLTTIGNWLRVVSRR 263
>gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
Length = 430
Score = 113 bits (282), Expect = 3e-25
Identities = 74/253 (29%), Positives = 125/253 (49%), Gaps = 31/253 (12%)
Query: 18 YLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYEELER-----VVLRLKPH 72
YL+ GA VF ALES E R R + A + +++ R + ++
Sbjct: 49 YLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRAD 108
Query: 73 KAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERI 132
+W F G+FYF TV++TIG+G P+T GGK F + Y L G T++ F ERI
Sbjct: 109 ALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERI 168
Query: 133 NTLVRYLLHRA---------------KKGLGMRRADVSMAN--------MVLIGFFSCIS 169
+L+ +++ ++G + AD S+A ++++G F+ +
Sbjct: 169 ISLLAFIMRACRERQLRRSGLLPATFRRGSALSEAD-SLAGWKPSVYHVLLILGLFAVLL 227
Query: 170 TLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYIL 229
+ C +A ++ E W + + Y+CF+T +TIGFGD V+ Q A + Q Y +F++IL
Sbjct: 228 S-CCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQ-HAAYRNQGLYRLGNFLFIL 285
Query: 230 TGLTVIGAFLNLV 242
G+ I + N++
Sbjct: 286 LGVCCIYSLFNVI 298
>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
[Homo sapiens]
Length = 332
Score = 112 bits (279), Expect = 8e-25
Identities = 76/254 (29%), Positives = 128/254 (50%), Gaps = 19/254 (7%)
Query: 8 TLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYN-LSQGGYEELERVV 66
T+ L++ YL +G VF LE + + + EL + L + + L R V
Sbjct: 22 TVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDV 81
Query: 67 LRLKPHKAGV--------QWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGI 118
++ + A + +W GSF+F+++ ITTIGYG+ +P+T ++FC+F+AL+GI
Sbjct: 82 VQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGI 141
Query: 119 PLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCIS----TLCIG 174
PL LV+ LG + V + R LG D A L G + +S L +
Sbjct: 142 PLNLVVLNRLGHLMQQGVNHWASR----LGGTWQDPDKARW-LAGSGALLSGLLLFLLLP 196
Query: 175 AAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTV 234
FSH E W++ + +Y+ FITL+T+GFGDYV + + + + Y ++IL G+
Sbjct: 197 PLLFSHMEGWSYTEGFYFAFITLSTVGFGDYV-IGMNPSQRYPLWYKNMVSLWILFGMAW 255
Query: 235 IGAFLNLVVLRFMT 248
+ + L++ + T
Sbjct: 256 LALIIKLILSQLET 269
>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
[Homo sapiens]
Length = 271
Score = 110 bits (274), Expect = 3e-24
Identities = 70/212 (33%), Positives = 110/212 (51%), Gaps = 18/212 (8%)
Query: 8 TLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYN-LSQGGYEELERVV 66
T+ L++ YL +G VF LE + + + EL + L + + L R V
Sbjct: 22 TVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDV 81
Query: 67 LRLKPHKAGV--------QWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGI 118
++ + A + +W GSF+F+++ ITTIGYG+ +P+T ++FC+F+AL+GI
Sbjct: 82 VQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGI 141
Query: 119 PLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCIS----TLCIG 174
PL LV+ LG + V + R LG D A L G + +S L +
Sbjct: 142 PLNLVVLNRLGHLMQQGVNHWASR----LGGTWQDPDKARW-LAGSGALLSGLLLFLLLP 196
Query: 175 AAAFSHYEHWTFFQAYYYCFITLTTIGFGDYV 206
FSH E W++ + +Y+ FITL+T+GFGDYV
Sbjct: 197 PLLFSHMEGWSYTEGFYFAFITLSTVGFGDYV 228
>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
Length = 313
Score = 106 bits (264), Expect = 4e-23
Identities = 74/208 (35%), Positives = 106/208 (50%), Gaps = 22/208 (10%)
Query: 18 YLLVGAAVFDALESEPELIERQRLE-LRQQELRARYNLSQGGYE----------ELERVV 66
YL++GA + LE E R LE LR Q L+ ++ + L RVV
Sbjct: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
Query: 67 LRLKPHKAGVQ---WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLV 123
L A W FA + +FA T+ITT+GYG+ P TD GK F + +ALLG+P T++
Sbjct: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
Query: 124 MFQSLGERINTLVRYLLHRAKKGLGMRRA--DVSMANMVLIGFFSCISTLC--IGAAAFS 179
+ + +R++ L L H L MR A L+ + T+C + A F+
Sbjct: 137 LLTASAQRLSLL---LTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIFA 193
Query: 180 HYEH-WTFFQAYYYCFITLTTIGFGDYV 206
H E W+F A+Y+CFI+L+TIG GDYV
Sbjct: 194 HLEEAWSFLDAFYFCFISLSTIGLGDYV 221
Score = 31.6 bits (70), Expect = 1.3
Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 7/57 (12%)
Query: 78 WRFAGSFYFAITVITTIGYGHAAPSTDGG-------KVFCMFYALLGIPLTLVMFQS 127
W F +FYF ++TIG G P G KV Y LG+ +++ Q+
Sbjct: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVLQT 255
>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
sapiens]
Length = 257
Score = 83.6 bits (205), Expect = 3e-16
Identities = 62/205 (30%), Positives = 89/205 (43%), Gaps = 11/205 (5%)
Query: 11 LIVCTFTYLLVGAAVFDALESEP--ELIERQRLELRQQELRARYNLSQGGYEELERVVLR 68
L+V L +GA VF ALE P L R EL + R L G EEL L
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 69 LKPH--------KAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120
+ H G W + FA +++TT GYGH AP + GGK FCM YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 121 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 180
+L + +L + ++ + A ++ V +G S + + A
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWG 192
Query: 181 YE-HWTFFQAYYYCFITLTTIGFGD 204
+ + A Y+CF +L+TIG D
Sbjct: 193 LQGDCSLLGAVYFCFSSLSTIGLED 217
>gi|16118231 potassium channel, subfamily K, member 7 isoform A
[Homo sapiens]
Length = 307
Score = 83.6 bits (205), Expect = 3e-16
Identities = 62/205 (30%), Positives = 89/205 (43%), Gaps = 11/205 (5%)
Query: 11 LIVCTFTYLLVGAAVFDALESEP--ELIERQRLELRQQELRARYNLSQGGYEELERVVLR 68
L+V L +GA VF ALE P L R EL + R L G EEL L
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 69 LKPH--------KAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120
+ H G W + FA +++TT GYGH AP + GGK FCM YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 121 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 180
+L + +L + ++ + A ++ V +G S + + A
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWG 192
Query: 181 YE-HWTFFQAYYYCFITLTTIGFGD 204
+ + A Y+CF +L+TIG D
Sbjct: 193 LQGDCSLLGAVYFCFSSLSTIGLED 217
>gi|16118235 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 83.6 bits (205), Expect = 3e-16
Identities = 62/205 (30%), Positives = 89/205 (43%), Gaps = 11/205 (5%)
Query: 11 LIVCTFTYLLVGAAVFDALESEP--ELIERQRLELRQQELRARYNLSQGGYEELERVVLR 68
L+V L +GA VF ALE P L R EL + R L G EEL L
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 69 LKPH--------KAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120
+ H G W + FA +++TT GYGH AP + GGK FCM YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 121 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 180
+L + +L + ++ + A ++ V +G S + + A
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWG 192
Query: 181 YE-HWTFFQAYYYCFITLTTIGFGD 204
+ + A Y+CF +L+TIG D
Sbjct: 193 LQGDCSLLGAVYFCFSSLSTIGLED 217
>gi|16118233 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 83.6 bits (205), Expect = 3e-16
Identities = 62/205 (30%), Positives = 89/205 (43%), Gaps = 11/205 (5%)
Query: 11 LIVCTFTYLLVGAAVFDALESEP--ELIERQRLELRQQELRARYNLSQGGYEELERVVLR 68
L+V L +GA VF ALE P L R EL + R L G EEL L
Sbjct: 13 LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72
Query: 69 LKPH--------KAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120
+ H G W + FA +++TT GYGH AP + GGK FCM YA LG+P
Sbjct: 73 TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132
Query: 121 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 180
+L + +L + ++ + A ++ V +G S + + A
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGLLVASSFVLLPALVLWG 192
Query: 181 YE-HWTFFQAYYYCFITLTTIGFGD 204
+ + A Y+CF +L+TIG D
Sbjct: 193 LQGDCSLLGAVYFCFSSLSTIGLED 217
>gi|32469495 potassium channel, subfamily K, member 18 [Homo
sapiens]
Length = 384
Score = 74.3 bits (181), Expect = 2e-13
Identities = 48/145 (33%), Positives = 71/145 (48%), Gaps = 8/145 (5%)
Query: 9 LALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQ--QELRARYNLSQGGYEE----L 62
L + TY LVGA VF A+E L+ E + +EL N S+ E+ L
Sbjct: 24 LCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDL 83
Query: 63 ERVVLRLKPH--KAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120
+ + ++KP W F S +F TV +T+GYG+ P T GK CM YAL GIPL
Sbjct: 84 QGHLQKVKPQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPL 143
Query: 121 TLVMFQSLGERINTLVRYLLHRAKK 145
++ G+ + T++ +R +K
Sbjct: 144 MFLVLTDTGDILATILSTSYNRFRK 168
Score = 48.5 bits (114), Expect = 1e-05
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 13/103 (12%)
Query: 146 GLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQ-AYYYCFITLTTIGFGD 204
G + R D+ + + LI F + + AA +E F+ A+Y+CF+TLTTIGFGD
Sbjct: 273 GQQVERLDIPLPIIALIVF----AYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGD 328
Query: 205 YVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFM 247
V P + F +YI+ G+ ++ LV R +
Sbjct: 329 TVL--------EHPNFFLFFSIYIIVGMEIVFIAFKLVQNRLI 363
Score = 35.4 bits (80), Expect = 0.090
Identities = 17/70 (24%), Positives = 33/70 (47%)
Query: 77 QWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLV 136
Q F +FYF +TTIG+G +F Y ++G+ + + F+ + R+ +
Sbjct: 307 QLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQNRLIDIY 366
Query: 137 RYLLHRAKKG 146
+ ++ KG
Sbjct: 367 KNVMLFFAKG 376
Score = 30.0 bits (66), Expect = 3.8
Identities = 8/26 (30%), Positives = 16/26 (61%)
Query: 178 FSHYEHWTFFQAYYYCFITLTTIGFG 203
F+ HW+F + ++C +T+G+G
Sbjct: 95 FNRTTHWSFLSSLFFCCTVFSTVGYG 120
>gi|22024390 potassium voltage-gated channel, subfamily H, member 5
isoform 1 [Homo sapiens]
Length = 988
Score = 42.0 bits (97), Expect = 0.001
Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 26/118 (22%)
Query: 51 RYNLSQGGYEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFC 110
RYN S G +E P K + + S YF +T +TTIG+G+ AP+TD K+F
Sbjct: 401 RYNTSAGIWEG--------GPSKDSL---YVSSLYFTMTSLTTIGFGNIAPTTDVEKMFS 449
Query: 111 MFYALLGIPLTLVMFQSL--------------GERINTLVRYL-LHRAKKGLGMRRAD 153
+ ++G L +F ++ E +N + +L L++ KGL R D
Sbjct: 450 VAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMD 507
>gi|27886648 potassium voltage-gated channel, subfamily H, member 5
isoform 2 [Homo sapiens]
Length = 624
Score = 42.0 bits (97), Expect = 0.001
Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 26/118 (22%)
Query: 51 RYNLSQGGYEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFC 110
RYN S G +E P K + + S YF +T +TTIG+G+ AP+TD K+F
Sbjct: 343 RYNTSAGIWEG--------GPSKDSL---YVSSLYFTMTSLTTIGFGNIAPTTDVEKMFS 391
Query: 111 MFYALLGIPLTLVMFQSL--------------GERINTLVRYL-LHRAKKGLGMRRAD 153
+ ++G L +F ++ E +N + +L L++ KGL R D
Sbjct: 392 VAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMD 449
>gi|27886646 potassium voltage-gated channel, subfamily H, member 5
isoform 3 [Homo sapiens]
Length = 611
Score = 42.0 bits (97), Expect = 0.001
Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 26/118 (22%)
Query: 51 RYNLSQGGYEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFC 110
RYN S G +E P K + + S YF +T +TTIG+G+ AP+TD K+F
Sbjct: 401 RYNTSAGIWEG--------GPSKDSL---YVSSLYFTMTSLTTIGFGNIAPTTDVEKMFS 449
Query: 111 MFYALLGIPLTLVMFQSL--------------GERINTLVRYL-LHRAKKGLGMRRAD 153
+ ++G L +F ++ E +N + +L L++ KGL R D
Sbjct: 450 VAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMD 507
>gi|4504831 potassium voltage-gated channel, subfamily H, member 1
isoform 2 [Homo sapiens]
Length = 962
Score = 41.6 bits (96), Expect = 0.001
Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 15/89 (16%)
Query: 80 FAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSL----------- 128
+ S YF +T +T++G+G+ APSTD K+F + ++G L +F ++
Sbjct: 423 YISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANT 482
Query: 129 ---GERINTLVRYL-LHRAKKGLGMRRAD 153
E +N++ +L L++ KGL R D
Sbjct: 483 NRYHEMLNSVRDFLKLYQVPKGLSERVMD 511
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,480,037
Number of Sequences: 37866
Number of extensions: 668380
Number of successful extensions: 7133
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 143
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 5876
Number of HSP's gapped (non-prelim): 871
length of query: 394
length of database: 18,247,518
effective HSP length: 104
effective length of query: 290
effective length of database: 14,309,454
effective search space: 4149741660
effective search space used: 4149741660
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.