Guide to the Human Genome
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Search of human proteins with 4504665

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]
         (551 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]      1152   0.0  
gi|31083174 interleukin 21 receptor precursor [Homo sapiens]           81   3e-15
gi|11141869 interleukin 21 receptor precursor [Homo sapiens]           81   3e-15
gi|31083180 interleukin 21 receptor precursor [Homo sapiens]           81   3e-15
gi|29171682 interleukin 9 receptor precursor [Homo sapiens]            72   2e-12
gi|166362732 ELK1 protein [Homo sapiens]                               44   3e-04
gi|166362730 ELK1 protein [Homo sapiens]                               44   3e-04
gi|4559408 colony stimulating factor 2 receptor, beta precursor ...    44   3e-04
gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]          42   0.001
gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]      42   0.001
gi|4503591 erythropoietin receptor precursor [Homo sapiens]            41   0.003
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]           41   0.003
gi|4557317 annexin A11 [Homo sapiens]                                  40   0.006
gi|22165433 annexin A11 [Homo sapiens]                                 40   0.006
gi|22165431 annexin A11 [Homo sapiens]                                 40   0.006
gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide...    40   0.007
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    39   0.009
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     39   0.009
gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre...    39   0.012
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    39   0.016
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    39   0.016
gi|115430248 gp130-like monocyte receptor [Homo sapiens]               39   0.016
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       39   0.016
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    39   0.016
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    38   0.021
gi|150170670 piccolo isoform 2 [Homo sapiens]                          38   0.021
gi|150378539 piccolo isoform 1 [Homo sapiens]                          38   0.021
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              38   0.028
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                38   0.028
gi|208022661 hypothetical protein LOC57701 [Homo sapiens]              38   0.028

>gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]
          Length = 551

 Score = 1152 bits (2980), Expect = 0.0
 Identities = 551/551 (100%), Positives = 551/551 (100%)

Query: 1   MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQ 60
           MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQ
Sbjct: 1   MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQ 60

Query: 61  VHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMA 120
           VHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMA
Sbjct: 61  VHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMA 120

Query: 121 IQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEE 180
           IQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEE
Sbjct: 121 IQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEE 180

Query: 181 APLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDT 240
           APLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDT
Sbjct: 181 APLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDT 240

Query: 241 IPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDV 300
           IPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDV
Sbjct: 241 IPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDV 300

Query: 301 QKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFT 360
           QKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFT
Sbjct: 301 QKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFT 360

Query: 361 NQGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCT 420
           NQGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCT
Sbjct: 361 NQGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCT 420

Query: 421 FPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVP 480
           FPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVP
Sbjct: 421 FPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVP 480

Query: 481 DLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQ 540
           DLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQ
Sbjct: 481 DLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQ 540

Query: 541 ELQGQDPTHLV 551
           ELQGQDPTHLV
Sbjct: 541 ELQGQDPTHLV 551


>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 99/380 (26%), Positives = 158/380 (41%), Gaps = 74/380 (19%)

Query: 8   WRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCV---WS------------QDG 52
           W  PLL+LLL     W      G     C+ +    + C+   W+            Q  
Sbjct: 5   WAAPLLLLLLQ--GGW------GCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYE 56

Query: 53  ALQD--TSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLC 110
            L+D  TSC +H    R   N T        A++ C++     D       DI ++ +  
Sbjct: 57  ELKDEATSCSLH----RSAHNAT-------HATYTCHM-----DVFHFMADDIFSVNITD 100

Query: 111 REGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQ---ASHYFERHLEF 167
           + G   +      F   E+++   P ++ V    + + NISW       A +  +  L++
Sbjct: 101 QSGNYSQECG--SFLLAESIKPAPPFNVTVTF--SGQYNISWRSDYEDPAFYMLKGKLQY 156

Query: 168 EARTLSPGHTWEEAP---LLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFT--TWSP 222
           E +  + G  W  +P   L+++  +   +       D+ YE QVR  P+ G     TWS 
Sbjct: 157 ELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSE 216

Query: 223 WSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNT 282
           WS P+ F+T+   L +    W  HLL+ L     FI   + L        W KK+     
Sbjct: 217 WSDPVIFQTQSEELKEG---WNPHLLLLLLLVIVFIPAFWSLKTHPLWRLW-KKIWA--V 270

Query: 283 PDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEI-SPLEV---------LERDK 332
           P P +FF  L     GD +KW+ +PF  SS   G  +PE+ S LEV          +R +
Sbjct: 271 PSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPAKRLQ 330

Query: 333 VTQL-----LLQQDKVPEPA 347
           +T+L     L++ D VP+P+
Sbjct: 331 LTELQEPAELVESDGVPKPS 350


>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 99/380 (26%), Positives = 158/380 (41%), Gaps = 74/380 (19%)

Query: 8   WRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCV---WS------------QDG 52
           W  PLL+LLL     W      G     C+ +    + C+   W+            Q  
Sbjct: 5   WAAPLLLLLLQ--GGW------GCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYE 56

Query: 53  ALQD--TSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLC 110
            L+D  TSC +H    R   N T        A++ C++     D       DI ++ +  
Sbjct: 57  ELKDEATSCSLH----RSAHNAT-------HATYTCHM-----DVFHFMADDIFSVNITD 100

Query: 111 REGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQ---ASHYFERHLEF 167
           + G   +      F   E+++   P ++ V    + + NISW       A +  +  L++
Sbjct: 101 QSGNYSQECG--SFLLAESIKPAPPFNVTVTF--SGQYNISWRSDYEDPAFYMLKGKLQY 156

Query: 168 EARTLSPGHTWEEAP---LLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFT--TWSP 222
           E +  + G  W  +P   L+++  +   +       D+ YE QVR  P+ G     TWS 
Sbjct: 157 ELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSE 216

Query: 223 WSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNT 282
           WS P+ F+T+   L +    W  HLL+ L     FI   + L        W KK+     
Sbjct: 217 WSDPVIFQTQSEELKEG---WNPHLLLLLLLVIVFIPAFWSLKTHPLWRLW-KKIWA--V 270

Query: 283 PDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEI-SPLEV---------LERDK 332
           P P +FF  L     GD +KW+ +PF  SS   G  +PE+ S LEV          +R +
Sbjct: 271 PSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPAKRLQ 330

Query: 333 VTQL-----LLQQDKVPEPA 347
           +T+L     L++ D VP+P+
Sbjct: 331 LTELQEPAELVESDGVPKPS 350


>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 99/380 (26%), Positives = 158/380 (41%), Gaps = 74/380 (19%)

Query: 8   WRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCV---WS------------QDG 52
           W  PLL+LLL     W      G     C+ +    + C+   W+            Q  
Sbjct: 5   WAAPLLLLLLQ--GGW------GCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYE 56

Query: 53  ALQD--TSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLC 110
            L+D  TSC +H    R   N T        A++ C++     D       DI ++ +  
Sbjct: 57  ELKDEATSCSLH----RSAHNAT-------HATYTCHM-----DVFHFMADDIFSVNITD 100

Query: 111 REGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQ---ASHYFERHLEF 167
           + G   +      F   E+++   P ++ V    + + NISW       A +  +  L++
Sbjct: 101 QSGNYSQECG--SFLLAESIKPAPPFNVTVTF--SGQYNISWRSDYEDPAFYMLKGKLQY 156

Query: 168 EARTLSPGHTWEEAP---LLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFT--TWSP 222
           E +  + G  W  +P   L+++  +   +       D+ YE QVR  P+ G     TWS 
Sbjct: 157 ELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSE 216

Query: 223 WSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNT 282
           WS P+ F+T+   L +    W  HLL+ L     FI   + L        W KK+     
Sbjct: 217 WSDPVIFQTQSEELKEG---WNPHLLLLLLLVIVFIPAFWSLKTHPLWRLW-KKIWA--V 270

Query: 283 PDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEI-SPLEV---------LERDK 332
           P P +FF  L     GD +KW+ +PF  SS   G  +PE+ S LEV          +R +
Sbjct: 271 PSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPAKRLQ 330

Query: 333 VTQL-----LLQQDKVPEPA 347
           +T+L     L++ D VP+P+
Sbjct: 331 LTELQEPAELVESDGVPKPS 350


>gi|29171682 interleukin 9 receptor precursor [Homo sapiens]
          Length = 521

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 75/287 (26%), Positives = 114/287 (39%), Gaps = 25/287 (8%)

Query: 34  FTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAP 93
           FTC  N+   I C WS     Q +S  +    ++        +L  S+    C ++L  P
Sbjct: 54  FTCLTNNILRIDCHWSAPELGQGSSPWLLFTSNQAPGGTHKCILRGSE----CTVVL--P 107

Query: 94  DSQKLTTVDIVTLRVL-CREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISW 152
               L   D  T+    C  G     +   ++ P  +++L  P  LQ  ++ +  C ++W
Sbjct: 108 PEAVLVPSDNFTITFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQS-NISSGHCILTW 166

Query: 153 EISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLET--LTPDTQYEFQVRV 210
            IS A       L +E         WE+A          W+ LE   L P   +E ++RV
Sbjct: 167 SISPALEPMTTLLSYELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRV 226

Query: 211 KPLQGEFTT---------WSPWSQPLAFRTKPAALGKDTIPW--LGHLLVGLSGAFGFII 259
           +    E            WS WSQP+ F+  P   G    PW   G+ LV +S       
Sbjct: 227 QMATLEDDVVEEERYTGQWSEWSQPVCFQA-PQRQGPLIPPWGWPGNTLVAVSIFLLLTG 285

Query: 260 LVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWLSS 306
             YLL       P +K++   N P P+ FF  L S H G+ Q W+ +
Sbjct: 286 PTYLLFKL---SPRVKRIFYQNVPSPAMFFQPLYSVHNGNFQTWMGA 329


>gi|166362732 ELK1 protein [Homo sapiens]
          Length = 428

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 28/65 (43%), Positives = 32/65 (49%), Gaps = 7/65 (10%)

Query: 395 GVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEER 454
           G AG    SSP+  QP  G          RD  L  SPSLLGGP P  T   GSG+G + 
Sbjct: 295 GQAGGHAASSPEISQPQKGRKP-------RDLELPLSPSLLGGPGPERTPGSGSGSGLQA 347

Query: 455 MPPSL 459
             P+L
Sbjct: 348 PGPAL 352


>gi|166362730 ELK1 protein [Homo sapiens]
          Length = 428

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 28/65 (43%), Positives = 32/65 (49%), Gaps = 7/65 (10%)

Query: 395 GVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEER 454
           G AG    SSP+  QP  G          RD  L  SPSLLGGP P  T   GSG+G + 
Sbjct: 295 GQAGGHAASSPEISQPQKGRKP-------RDLELPLSPSLLGGPGPERTPGSGSGSGLQA 347

Query: 455 MPPSL 459
             P+L
Sbjct: 348 PGPAL 352


>gi|4559408 colony stimulating factor 2 receptor, beta precursor
           [Homo sapiens]
          Length = 897

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 93/379 (24%), Positives = 145/379 (38%), Gaps = 75/379 (19%)

Query: 133 MAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEW 192
           MAP SL V   +    ++ WE  +  +    H  FE +      TW+++   TL Q    
Sbjct: 340 MAPPSLNVTK-DGDSYSLRWETMKMRYEHIDHT-FEIQYRKDTATWKDSKTETL-QNAHS 396

Query: 193 ICLETLTPDTQYEFQVRVKPLQGEFT-TWSPWSQPLAFRTKPAALGKDTIP-WLGHLLVG 250
           + L  L P T+Y  +VRV+  +  +   WS WS+  ++ T+        +P W+  L+V 
Sbjct: 397 MALPALEPSTRYWARVRVRTSRTGYNGIWSEWSEARSWDTE------SVLPMWVLALIV- 449

Query: 251 LSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPS 310
               F  I ++  L  C   G  L++  +   P+PSK  S L     G  + W   P   
Sbjct: 450 ---IFLTIAVLLALRFCGIYGYRLRRKWEEKIPNPSK--SHLFQN--GSAELW--PPGSM 500

Query: 311 SSFSPG----------------GLAP------EISPLEVLERDKV-------------TQ 335
           S+F+ G                G+ P      E+SPL + +   V             + 
Sbjct: 501 SAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAASD 560

Query: 336 LLLQQDKVPEPASLSSNHS---LTSCFTNQGYFFF-----HLPDALEIEACQVYFTYDPY 387
           L  +Q   P+P   +++H+     S F   G +        LPD L     Q     +  
Sbjct: 561 LPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILG----QPEPPQEGG 616

Query: 388 SEEDPDEGVAG---APTGSSPQ--PLQPLSGEDDAYCTFPSRDDLLLFSPSLL--GGPSP 440
           S++ P  G       P G   Q  PL    G   A             SPSL   GGP+P
Sbjct: 617 SQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAP 676

Query: 441 PSTAPGGSGAGEERMPPSL 459
           P+  P   G  ++  P ++
Sbjct: 677 PALGPRVGGQDQKDSPVAI 695



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 41/142 (28%), Positives = 59/142 (41%), Gaps = 20/142 (14%)

Query: 98  LTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEI--- 154
           +T VD  + +     G R  V   Q  +P E      P  LQ+   + H   ++W +   
Sbjct: 105 VTDVDYFSFQPDRPLGTRLTVTLTQHVQPPE------PRDLQISTDQDHFL-LTWSVALG 157

Query: 155 SQASHYFER-HLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVK-- 211
           S  SH+     LEFE        +WE+A +L     Q  +  E L P + Y  +VR +  
Sbjct: 158 SPQSHWLSPGDLEFEVVYKRLQDSWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLA 217

Query: 212 ---PLQGEFTTWSP---W-SQP 226
               L G  + WSP   W SQP
Sbjct: 218 PGSRLSGRPSKWSPEVCWDSQP 239


>gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]
          Length = 379

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 40/138 (28%), Positives = 56/138 (40%), Gaps = 11/138 (7%)

Query: 394 EGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFS-------PSLLGGPSPPSTAPG 446
           E  A +P+ +SP P  P     + +     R  L  ++       PSL  GP  P     
Sbjct: 221 EAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGP 280

Query: 447 GSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPR 506
             GA ++R  P+   R  +   P P  P T     L  F  PP LV+ E G+  P +  R
Sbjct: 281 ARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLR 340

Query: 507 -EGVSFPWSRPPGQGEFR 523
            +G S P   PP    +R
Sbjct: 341 LQGDSKP---PPAHPLWR 355



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 27/78 (34%), Positives = 30/78 (38%), Gaps = 17/78 (21%)

Query: 439 SPPSTAPG-----GSGAGEERMPPSLQERVPRDWDPQPLGPPT------PGVPDLVDFQP 487
           +PP  APG     G  A   + P S     P     +P GP T      PG P  VD  P
Sbjct: 156 APPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNP 215

Query: 488 PPELVLREAGEEVPDAGP 505
           PP      A  E P A P
Sbjct: 216 PP------AAPEAPAASP 227


>gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]
          Length = 369

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 72/361 (19%), Positives = 129/361 (35%), Gaps = 55/361 (15%)

Query: 16  LLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAW---PDRRRWNQ 72
           L  + T   S +     +  CF  +   ++C W+     Q T+  +H W    D  +  +
Sbjct: 42  LTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQK 101

Query: 73  TCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRL 132
               L   + +  C L       QK       T  V  ++    R  A Q  K  +NL +
Sbjct: 102 CSHYLFSEEITSGCQL-------QKKEIHLYQTFVVQLQDPREPRRQATQMLK-LQNLVI 153

Query: 133 -MAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQE 191
             AP +L +  +   +  ++W     +H  E  +++        H+W E  +      + 
Sbjct: 154 PWAPENLTLHKLSESQLELNWNNRFLNHCLEHLVQYRT---DWDHSWTEQSV----DYRH 206

Query: 192 WICLETLTPDTQYEFQVRVK--PLQGEFTTWSPWSQPLAF-----RTKPAALGKDTIPWL 244
              L ++    +Y F+VR +  PL G    WS WS P+ +     +  P     + +   
Sbjct: 207 KFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVV-- 264

Query: 245 GHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWL 304
             + VG  G    ++ VY          WL++ +        K    L +E+ G+   W 
Sbjct: 265 --ISVGSMGLIISLLCVYF---------WLERTMP--RIPTLKNLEDLVTEYHGNFSAW- 310

Query: 305 SSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFTNQGY 364
                  S    GLA  + P      D   +L L  +  P+  +L      + C  +  Y
Sbjct: 311 -------SGVSKGLAESLQP------DYSERLCLVSEIPPKGGALGEGPGASPCNQHSPY 357

Query: 365 F 365
           +
Sbjct: 358 W 358


>gi|4503591 erythropoietin receptor precursor [Homo sapiens]
          Length = 508

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 65/291 (22%), Positives = 108/291 (37%), Gaps = 32/291 (10%)

Query: 24  ASAAVNGTSQFTCFYNSRANISCVWSQDGAL------QDTSCQVHAWPDRRRWNQTCELL 77
           A  A  G  +  CF     ++ C W +  +          S Q+   P    W + C L 
Sbjct: 40  ALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEP----W-KLCRLH 94

Query: 78  PVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVR--WRVMAIQDFKPFENLRLMAP 135
               A  A       P +   + V +  LRV    G     RV+ I      E + L AP
Sbjct: 95  QAPTARGAVRFWCSLPTADTSSFVPL-ELRVTAASGAPRYHRVIHIN-----EVVLLDAP 148

Query: 136 ISLQV-VHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWIC 194
           + L   +  E+    + W +         H+ +E   +S G+       + + + +    
Sbjct: 149 VGLVARLADESGHVVLRW-LPPPETPMTSHIRYEV-DVSAGNGAGSVQRVEILEGRTECV 206

Query: 195 LETLTPDTQYEFQVRVKPLQGEFTT-WSPWSQPLAFRTKPAALGKDTIPWLGHLLVGLSG 253
           L  L   T+Y F VR +  +  F   WS WS+P++  T            L  L++ LS 
Sbjct: 207 LSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD---------LDPLILTLSL 257

Query: 254 AFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWL 304
               I+++  ++   +    LK+ +    P P   F  L + H G+ Q WL
Sbjct: 258 ILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWL 308


>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
          Length = 1006

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 59/214 (27%), Positives = 75/214 (35%), Gaps = 33/214 (15%)

Query: 306 SPFPSSSFSPG-GLAPEISPLEVLER--DKVTQLLLQQDKVPEPASLSSNHSLTSCFTNQ 362
           SP P S    G GLAP  SP    +   D   +        P PA L+  H  T+C  + 
Sbjct: 768 SPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPA-LADYHECTACRVS- 825

Query: 363 GYFFFHLPDALEIEACQVYFTYDPYS-EEDPDEGVAGAPTGSSPQ--PLQPLSGEDDAYC 419
               FH        + + Y  +  YS    P  G  G P  + P   P  P+ G  D   
Sbjct: 826 ----FH--------SLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRG--DLLE 871

Query: 420 TFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMP---PSLQERVPRDW------DPQ 470
            F     LLL +P  L GP   +  P   G      P   P    R PRD       +P 
Sbjct: 872 HFRLAHGLLLGAP--LAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPP 929

Query: 471 PLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAG 504
           P  PP+P         PP      + G + P  G
Sbjct: 930 PGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKG 963


>gi|4557317 annexin A11 [Homo sapiens]
          Length = 505

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 50/168 (29%), Positives = 66/168 (39%), Gaps = 36/168 (21%)

Query: 381 YFTYDPYSEEDPDEGVAGAPTGSS---PQPLQPLSGEDDA--YCTFPSRDDLLLFSPSL- 434
           Y  Y P     P     G P G +   P P  P  G D+   Y    ++D L   + ++ 
Sbjct: 3   YPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMS 62

Query: 435 --LGGPSPPSTAPGGSGAGEERM-------PPSLQERV-PRDWDPQPLG---------PP 475
              GG + P+  PG  GAG   +       PPS Q+ V P    P P G         PP
Sbjct: 63  GTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPP 122

Query: 476 TPGVPDLVDFQPPPELVLREAGEEVPDAGP-REGVSFPWSRP---PGQ 519
            PG P      PPP       G++ P A P +  V++P   P   PGQ
Sbjct: 123 YPGAPVPGQPMPPP-------GQQPPGAYPGQPPVTYPGQPPVPLPGQ 163


>gi|22165433 annexin A11 [Homo sapiens]
          Length = 505

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 50/168 (29%), Positives = 66/168 (39%), Gaps = 36/168 (21%)

Query: 381 YFTYDPYSEEDPDEGVAGAPTGSS---PQPLQPLSGEDDA--YCTFPSRDDLLLFSPSL- 434
           Y  Y P     P     G P G +   P P  P  G D+   Y    ++D L   + ++ 
Sbjct: 3   YPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMS 62

Query: 435 --LGGPSPPSTAPGGSGAGEERM-------PPSLQERV-PRDWDPQPLG---------PP 475
              GG + P+  PG  GAG   +       PPS Q+ V P    P P G         PP
Sbjct: 63  GTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPP 122

Query: 476 TPGVPDLVDFQPPPELVLREAGEEVPDAGP-REGVSFPWSRP---PGQ 519
            PG P      PPP       G++ P A P +  V++P   P   PGQ
Sbjct: 123 YPGAPVPGQPMPPP-------GQQPPGAYPGQPPVTYPGQPPVPLPGQ 163


>gi|22165431 annexin A11 [Homo sapiens]
          Length = 505

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 50/168 (29%), Positives = 66/168 (39%), Gaps = 36/168 (21%)

Query: 381 YFTYDPYSEEDPDEGVAGAPTGSS---PQPLQPLSGEDDA--YCTFPSRDDLLLFSPSL- 434
           Y  Y P     P     G P G +   P P  P  G D+   Y    ++D L   + ++ 
Sbjct: 3   YPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMS 62

Query: 435 --LGGPSPPSTAPGGSGAGEERM-------PPSLQERV-PRDWDPQPLG---------PP 475
              GG + P+  PG  GAG   +       PPS Q+ V P    P P G         PP
Sbjct: 63  GTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPP 122

Query: 476 TPGVPDLVDFQPPPELVLREAGEEVPDAGP-REGVSFPWSRP---PGQ 519
            PG P      PPP       G++ P A P +  V++P   P   PGQ
Sbjct: 123 YPGAPVPGQPMPPP-------GQQPPGAYPGQPPVTYPGQPPVPLPGQ 163


>gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide
           [Homo sapiens]
          Length = 1634

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 51/187 (27%), Positives = 74/187 (39%), Gaps = 16/187 (8%)

Query: 321 EISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFTNQGYFFFHLPDA--LEIEAC 378
           E++  E L+ +      L+ DK    A  +++ SL S +   G  F+  P     +++  
Sbjct: 23  ELAMAEALQMEYDALSRLRHDKEENRAKQNADPSLIS-WDEPGVDFYSKPAGRRTDLKLL 81

Query: 379 QVYFTYDP---YSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLL 435
           +     DP   Y+   P EG     T   PQP     G D       S D L +F  S  
Sbjct: 82  RGLSGSDPTLNYNSLSPQEGPPNHSTSQGPQP-----GSDPWPKGSLSGDYLYIFDGSDG 136

Query: 436 GGPSPPSTAPGG-SGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLR 494
           G  S P   PG   G+ ++  PP L  R    WD  PL PP  G P       P ++   
Sbjct: 137 GVSSSP--GPGDIEGSCKKLSPPPLPPRA-SIWDTPPL-PPRKGSPSSSKISQPSDINTF 192

Query: 495 EAGEEVP 501
              E++P
Sbjct: 193 SLVEQLP 199


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 48/158 (30%), Positives = 55/158 (34%), Gaps = 25/158 (15%)

Query: 392 PDEGVAGAPTGSSPQPL-----QPLSGEDDAYCTFPSRDDL----LLFSPSLLG----GP 438
           P  G  G P    P P       PL+G        P+R D     +LF     G    GP
Sbjct: 239 PPLGPPGPPGPPGPPPPGQVLPPPLAGP-------PNRGDRPPPPVLFPGQPFGQPPLGP 291

Query: 439 SPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGE 498
            PP   P   G G    PP  Q+  P    P P  PP P  P L    PPP L     G 
Sbjct: 292 LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT-LAPPPHLPGPPPG- 349

Query: 499 EVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAY 536
             P   P    +F    PP        ++R P  TD Y
Sbjct: 350 -APPPAPHVNPAF--FPPPTNSGMPTSDSRGPPPTDPY 384



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 42/139 (30%), Positives = 47/139 (33%), Gaps = 19/139 (13%)

Query: 394 EGVAGAPTGSSPQPL-QPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGE 452
           EG AG P GSS     Q   G        P  D      P+  GGP PP   P G     
Sbjct: 183 EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFP--GPAGPGGPPPP--FPAGQTPPR 238

Query: 453 ERMPPSLQERVPRDWDP-QPLGPPTPGVPDLVDFQPPPELVLREAGEE------------ 499
             + P      P    P Q L PP  G P+  D  PPP L   +   +            
Sbjct: 239 PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPP 298

Query: 500 -VPDAGPREGVSFPWSRPP 517
            VP  GP  G   P   PP
Sbjct: 299 PVPGYGPPPGPPPPQQGPP 317


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 33/100 (33%), Positives = 39/100 (39%), Gaps = 19/100 (19%)

Query: 437 GPSPPSTAPG-----GSGAGEERMPPSLQERVPRDWDPQPLGPP-TPGVPDLVDFQPPPE 490
           GP PP    G     GS +   R PP   +  P     QP GPP  PG P      PPP+
Sbjct: 276 GPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ----GPPPQ 331

Query: 491 LVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLP 530
                 G   P   P  G       PP QG  ++ +AR P
Sbjct: 332 ------GGNKPQGPPPPGKP---QGPPPQGGSKSRSARSP 362



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 18/99 (18%)

Query: 437 GPSPPSTAPGGSGAGEE----RMPPSLQERVPRDWDPQPLG-PPTPGVPDLVDFQPPPEL 491
           GP PP    G    G++    R PP   +  P     QP G PP PG P      PPP+ 
Sbjct: 91  GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ----GPPPQ- 145

Query: 492 VLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLP 530
                G   P   P  G       PP QG+ ++ ++R P
Sbjct: 146 -----GGNKPQGPPPPGKP---QGPPPQGDNKSRSSRSP 176



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 28/86 (32%), Positives = 33/86 (38%), Gaps = 13/86 (15%)

Query: 437 GPSPPSTAPG-----GSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPEL 491
           GP PP    G     GS +   R PP   +  P+     P GPP P   +    Q PP  
Sbjct: 338 GPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP-- 395

Query: 492 VLREAGEEVPDAGPREGVSFPWSRPP 517
               AG+  P   PR       SRPP
Sbjct: 396 ----AGQ--PQGPPRPPQGGRPSRPP 415



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 29/92 (31%), Positives = 35/92 (38%), Gaps = 14/92 (15%)

Query: 431 SPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLG-PPTPGVPDLVDFQPPP 489
           SPSL+ G    +   GG+       PP   +  P     QP G PP PG P      PPP
Sbjct: 28  SPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQ----GPPP 83

Query: 490 ELVLREAGEEVPDAGPREGVSFPWSRPPGQGE 521
           +      G   P   P  G       PP QG+
Sbjct: 84  Q------GGNKPQGPPPPGKP---QGPPPQGD 106



 Score = 33.9 bits (76), Expect = 0.40
 Identities = 27/97 (27%), Positives = 36/97 (37%), Gaps = 10/97 (10%)

Query: 431 SPSLLGGPSPPSTAP--GGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPP 488
           S S    P  P   P  GG+       PP   +  P     +P GPP PG P      PP
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ----GPP 287

Query: 489 PELVLREAGEEVPDAGPR----EGVSFPWSRPPGQGE 521
           P+   +      P   P+    +G + P   PP  G+
Sbjct: 288 PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK 324



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 29/104 (27%), Positives = 38/104 (36%), Gaps = 9/104 (8%)

Query: 422 PSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPD 481
           P  D+    S S  G P  P    G    G    PP   +  P     +P GPP PG P 
Sbjct: 164 PQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP-PPGKPQGPPPQGGNKPQGPPPPGKPQ 222

Query: 482 LVDFQPPPELVLREAGEEVPDAGPR----EGVSFPWSRPPGQGE 521
                PPP+   +      P   P+    +G + P   PP  G+
Sbjct: 223 ----GPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK 262


>gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3
           preproprotein [Homo sapiens]
          Length = 178

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 31/102 (30%), Positives = 41/102 (40%), Gaps = 7/102 (6%)

Query: 431 SPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPE 490
           SPSL+ G     +  GG+       PP   +  P     +P GPP PG P      PPP+
Sbjct: 28  SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ----GPPPQ 83

Query: 491 LVLREAGEEVP--DAGPREGVSFPWSRPPGQGEFRALNARLP 530
                +    P    GP      P   PP QG  ++ +AR P
Sbjct: 84  GDKSRSPRSPPGKPQGPPPQGGKP-QGPPAQGGSKSQSARSP 124



 Score = 36.6 bits (83), Expect = 0.061
 Identities = 34/120 (28%), Positives = 43/120 (35%), Gaps = 12/120 (10%)

Query: 398 GAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPP 457
           G P    PQ   P   +  +  + P +       P   GG      A GGS +   R PP
Sbjct: 70  GPPPPGKPQGPPPQGDKSRSPRSPPGKPQ----GPPPQGGKPQGPPAQGGSKSQSARSPP 125

Query: 458 SLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPP 517
              +  P+     P GPP P   +    Q PP      AG+  P   PR       SRPP
Sbjct: 126 GKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP------AGQ--PQGPPRPPQGGRPSRPP 177


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 38/125 (30%), Positives = 44/125 (35%), Gaps = 27/125 (21%)

Query: 400 PTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSL 459
           P+   P PL P S  +D     P R+         L   +PP  +PG SG     +PP  
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRN-------LSLSSSTPPLPSPGRSGP----LPPPP 361

Query: 460 QERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEE-----VPDAGPREGVSFPWS 514
            ER P         PP    P      PPP  V R           P    R GV  P S
Sbjct: 362 SERPP---------PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412

Query: 515 --RPP 517
             RPP
Sbjct: 413 GPRPP 417



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 24/65 (36%), Positives = 28/65 (43%), Gaps = 11/65 (16%)

Query: 436 GGPSPPSTAPGG-SGAGEERMPPSLQERVP------RDWDPQP----LGPPTPGVPDLVD 484
           GG  PP   PGG S + +   PPS   R P      R   P+P    + PP P V    D
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181

Query: 485 FQPPP 489
             PPP
Sbjct: 182 SIPPP 186


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 38/125 (30%), Positives = 44/125 (35%), Gaps = 27/125 (21%)

Query: 400 PTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSL 459
           P+   P PL P S  +D     P R+         L   +PP  +PG SG     +PP  
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRN-------LSLSSSTPPLPSPGRSGP----LPPPP 361

Query: 460 QERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEE-----VPDAGPREGVSFPWS 514
            ER P         PP    P      PPP  V R           P    R GV  P S
Sbjct: 362 SERPP---------PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412

Query: 515 --RPP 517
             RPP
Sbjct: 413 GPRPP 417



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 24/65 (36%), Positives = 28/65 (43%), Gaps = 11/65 (16%)

Query: 436 GGPSPPSTAPGG-SGAGEERMPPSLQERVP------RDWDPQP----LGPPTPGVPDLVD 484
           GG  PP   PGG S + +   PPS   R P      R   P+P    + PP P V    D
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181

Query: 485 FQPPP 489
             PPP
Sbjct: 182 SIPPP 186


>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
          Length = 764

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 52/223 (23%), Positives = 92/223 (41%), Gaps = 28/223 (12%)

Query: 16  LLPLATSWASAAVNGTSQ-FTCFYNSRANISCVWS---QDGALQDTSCQVHAWPDRRRWN 71
           +LP    ++ AA+    +  +C Y  R N++C WS   +    Q T  + +A+ ++    
Sbjct: 41  MLPSLCKFSLAALPAKPENISCVYYYRKNLTCTWSPGKETSYTQYTVKRTYAFGEKHDNC 100

Query: 72  QTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREG--------VRWRVMAIQD 123
            T      ++AS  C+  L      ++T  D  T+ V    G          WR+  I  
Sbjct: 101 TTNSSTSENRAS--CSFFL-----PRITIPDNYTIEVEAENGDGVIKSHMTYWRLENIAK 153

Query: 124 FKPFENLRLMAPISL-QVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAP 182
            +P +  R+   + + +++ +E     I  E++  S   +  L F  RT++     E   
Sbjct: 154 TEPPKIFRVKPVLGIKRMIQIEW----IKPELAPVSSDLKYTLRF--RTVNSTSWMEVNF 207

Query: 183 LLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQ 225
               K K +   L  L P T+Y   +R    + +F  WS WSQ
Sbjct: 208 AKNRKDKNQTYNLTGLQPFTEYVIALRCAVKESKF--WSDWSQ 248


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 7/96 (7%)

Query: 398 GAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPP 457
           G P GS P P  P S +      FP  D  + F+P L    +P  T PG      ++ PP
Sbjct: 680 GLPVGSVPAPACPPSLQQH----FP--DPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPP 733

Query: 458 SLQER-VPRDWDPQPLGPPTPGVPDLVDFQPPPELV 492
             Q   +P+   PQP+ P  P  P L  +  P   V
Sbjct: 734 LAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQV 769



 Score = 33.9 bits (76), Expect = 0.40
 Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 16/106 (15%)

Query: 385  DPYSEEDPDEGVAGAPTG--SSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLG----GP 438
            +P S      G  G P G  S  +  QPL+   +A          L   P ++G     P
Sbjct: 1408 EPASGTASQAGGPGTPQGLTSELETSQPLAETHEAP---------LAVQPLVVGLAPCTP 1458

Query: 439  SPPSTAPGGSGAGEERMPPSLQERVPRDWDPQP-LGPPTPGVPDLV 483
            +P + +   + A  E +PP   E  P    PQP LG P P +P  V
Sbjct: 1459 APEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAV 1504



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 38/130 (29%), Positives = 43/130 (33%), Gaps = 47/130 (36%)

Query: 389 EEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLL------GGPSPPS 442
           EE P    A AP    PQPLQ              R  LLL     L      G P+ P+
Sbjct: 52  EEPPGLEAAEAPGPQPPQPLQ--------------RRVLLLCKTRRLIAERARGRPAAPA 97

Query: 443 TA-----PGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAG 497
            A     PG  GA             P D  P+P+G   PG         P  +      
Sbjct: 98  PAALVAQPGAPGA-------------PADAGPEPVGTQEPG---------PDPIAAAVET 135

Query: 498 EEVPDAGPRE 507
              PD GPRE
Sbjct: 136 APAPDGGPRE 145


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 41/143 (28%), Positives = 51/143 (35%), Gaps = 22/143 (15%)

Query: 388 SEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGG 447
           S+E+    +AG P G SPQ      G        P +       P   GG  P    P G
Sbjct: 24  SQEESPSLIAGNPQGPSPQGGNKPQGPPPP----PGKPQ----GPPPQGGNKPQGPPPPG 75

Query: 448 SGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPRE 507
              G    P   + R PR    +P GPP  G        PPP+      G   P   P  
Sbjct: 76  KPQGPP--PQGDKSRSPRSPPGKPQGPPPQGGKPQ---GPPPQ------GGNKPQGPPPP 124

Query: 508 GVSFPWSRPPGQGEFRALNARLP 530
           G       PP QG  ++ +AR P
Sbjct: 125 GKP---QGPPAQGGSKSQSARSP 144



 Score = 36.6 bits (83), Expect = 0.061
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 13/86 (15%)

Query: 437 GPSPPST-----APGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPEL 491
           GP PP       A GGS +   R PP   +  P+     P GPP P   +    Q PP  
Sbjct: 120 GPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP-- 177

Query: 492 VLREAGEEVPDAGPREGVSFPWSRPP 517
               AG+  P   PR       SRPP
Sbjct: 178 ----AGQ--PQGPPRPPQGGRPSRPP 197


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
            potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 56/205 (27%), Positives = 68/205 (33%), Gaps = 30/205 (14%)

Query: 340  QDKVPEPASLSSNHSLTSCFTNQGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGA 399
            Q  +P     +S  S  S         FH+       A        P S   P  G  G+
Sbjct: 830  QSLIPSALGSASPASSPSQVDTPSSSSFHIQQLAGFSAPAGLSPLLPSSSSSPPPGACGS 889

Query: 400  PTGSSPQP------LQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSP----PSTAP---- 445
            P+  +P        +        A     S  D  L +P   G  SP    PS AP    
Sbjct: 890  PSAPTPSAGVAATTIAGFGHFHKALGGSLSSSDSPLLTPLQPGARSPQAAQPSPAPPGAR 949

Query: 446  GGSGAGEERMPPSLQERVPRDWDPQPLGPPTPG------------VPDLVDFQP-PPELV 492
            GG G  E  +PP    R P    P  LG P PG             P+    QP PP LV
Sbjct: 950  GGLGLPEHFLPPPPSSRSPSS-SPGQLGQP-PGELSLGLATGPLSTPETPPRQPEPPSLV 1007

Query: 493  LREAGEEVP-DAGPREGVSFPWSRP 516
               +G   P    PR G+S P   P
Sbjct: 1008 AGASGGASPVGFTPRGGLSPPGHSP 1032


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 39/143 (27%), Positives = 58/143 (40%), Gaps = 20/143 (13%)

Query: 399 APTGSSPQPLQPLSGEDDA------YCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGE 452
           A + SSPQP Q    +D A          P +   L+  P+L G PS  +  P  + +  
Sbjct: 671 AVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS 730

Query: 453 ERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPREGVSFP 512
           +  PP  +  VP + D  P+    P  P +V  +P  +LV   +    PD         P
Sbjct: 731 KPAPPK-EPSVPSEQDKAPVADDKPKQPKMV--KPTTDLVSSSSATTKPD--------IP 779

Query: 513 WSRPPGQGEFRALNARLPLNTDA 535
            S+   Q E +      PL TD+
Sbjct: 780 SSKVQSQAEEKTTP---PLKTDS 799


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 39/143 (27%), Positives = 58/143 (40%), Gaps = 20/143 (13%)

Query: 399 APTGSSPQPLQPLSGEDDA------YCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGE 452
           A + SSPQP Q    +D A          P +   L+  P+L G PS  +  P  + +  
Sbjct: 671 AVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS 730

Query: 453 ERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPREGVSFP 512
           +  PP  +  VP + D  P+    P  P +V  +P  +LV   +    PD         P
Sbjct: 731 KPAPPK-EPSVPSEQDKAPVADDKPKQPKMV--KPTTDLVSSSSATTKPD--------IP 779

Query: 513 WSRPPGQGEFRALNARLPLNTDA 535
            S+   Q E +      PL TD+
Sbjct: 780 SSKVQSQAEEKTTP---PLKTDS 799


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 37.7 bits (86), Expect = 0.028
 Identities = 41/157 (26%), Positives = 56/157 (35%), Gaps = 26/157 (16%)

Query: 392 PDEGVAGAPT--------GSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPST 443
           P+ G  G P         G  P P  P S E     T P + +      + L GP     
Sbjct: 842 PENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRK 901

Query: 444 APGGSGAGEERMPPSLQE-RVPRDWDPQP------LGPPTPGVPDL----VDFQPPPELV 492
              G G+G +  PP  +E R    W P+P      + P  PG P      +   PPP  V
Sbjct: 902 PARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKV 961

Query: 493 LREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARL 529
                EE+P     +G   P  +PP     +    +L
Sbjct: 962 -----EELPPKPLEQGDETP--KPPKPDPLKITKGKL 991



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 47/203 (23%), Positives = 57/203 (28%), Gaps = 56/203 (27%)

Query: 386 PYSEEDPDEGVAGAPTGSSPQP---LQP--LSGEDDAYCTFPSRDDLLLFSPSLLG--GP 438
           P  E +P+E     P  S+P P     P  +SG      T     +     P L    GP
Sbjct: 540 PTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGP 599

Query: 439 SPPSTAPG------------GSGAGEERMPPS------------------------LQER 462
            PP   P             G G G  R PPS                        L+++
Sbjct: 600 EPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQ 659

Query: 463 VPRDWD----------PQPLGPPTP---GVPDLVDFQPPPELVLREAGEEVPDAGPREGV 509
               W           P P  PP P   G        PPP   L       P   P    
Sbjct: 660 QQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNF 719

Query: 510 SFPWSRPPGQGEFRALNARLPLN 532
              W   P   + R L  R PL+
Sbjct: 720 DPRWMMIPPYVDPRLLQGRPPLD 742


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 37.7 bits (86), Expect = 0.028
 Identities = 30/88 (34%), Positives = 34/88 (38%), Gaps = 10/88 (11%)

Query: 438 PSPPSTA-PGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREA 496
           P PPS   P  S  G    PP +    P    P P+ PP    P +    PPP +    A
Sbjct: 215 PPPPSAPNPVVSSLGSGLPPPGMP---PPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAA 271

Query: 497 GEEVPDAG------PREGVSFPWSRPPG 518
           G   P AG      P  G S P   PPG
Sbjct: 272 GHGPPSAGTPGAGHPGHGHSHPHPFPPG 299


>gi|208022661 hypothetical protein LOC57701 [Homo sapiens]
          Length = 1334

 Score = 37.7 bits (86), Expect = 0.028
 Identities = 47/148 (31%), Positives = 62/148 (41%), Gaps = 28/148 (18%)

Query: 394 EGVAGAPTGSSPQPLQPLSGE----DDAYCTF--------PSRDDLLLFSPSLLGGPSP- 440
           EG  G PT  SP    P S +      A  T         P  +++L  S S   GPSP 
Sbjct: 514 EGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPE 573

Query: 441 PSTAPGGSGAGEERMP--PSLQERVPRDWDP--QPLGPPTPGVPDLVDFQPPPELVLREA 496
           P  +P        ++P  P L   VP+  +    P  PP+P +P+   +  P E  L +A
Sbjct: 574 PPPSP-------LQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYGSPQEKSLDKA 626

Query: 497 GEEVPDAGPR-EGVSFPWSRPPGQGEFR 523
           G E P  G R  G S   S+ P QG  R
Sbjct: 627 GSESPHPGRRTPGNS---SKKPSQGSGR 651


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,950,521
Number of Sequences: 37866
Number of extensions: 1691518
Number of successful extensions: 7741
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 355
Number of HSP's that attempted gapping in prelim test: 6831
Number of HSP's gapped (non-prelim): 1091
length of query: 551
length of database: 18,247,518
effective HSP length: 107
effective length of query: 444
effective length of database: 14,195,856
effective search space: 6302960064
effective search space used: 6302960064
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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