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Search of human proteins with 4502643
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502643 chaperonin containing TCP1, subunit 6A isoform a
[Homo sapiens]
(531 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom... 1027 0.0
gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho... 921 0.0
gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] 901 0.0
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom... 265 6e-71
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom... 264 1e-70
gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom... 250 2e-66
gi|57863257 T-complex protein 1 isoform a [Homo sapiens] 242 5e-64
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo... 236 4e-62
gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ... 235 7e-62
gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom... 224 2e-58
gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens] 214 2e-55
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ... 176 5e-44
gi|57863259 T-complex protein 1 isoform b [Homo sapiens] 142 1e-33
gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom... 133 5e-31
gi|7657253 T-complex protein 1 [Homo sapiens] 130 3e-30
gi|41399285 chaperonin [Homo sapiens] 62 2e-09
gi|31542947 chaperonin [Homo sapiens] 62 2e-09
gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens] 47 6e-05
gi|21735548 centrosomal protein 2 [Homo sapiens] 36 0.077
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 35 0.22
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 33 0.85
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 33 0.85
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 33 0.85
gi|70980531 GGA binding partner [Homo sapiens] 33 0.85
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 33 0.85
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 32 1.1
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 32 1.1
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 32 1.1
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 32 1.1
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 32 1.1
>gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo
sapiens]
Length = 531
Score = 1027 bits (2656), Expect = 0.0
Identities = 531/531 (100%), Positives = 531/531 (100%)
Query: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60
MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
Sbjct: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60
Query: 61 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT 120
NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT
Sbjct: 61 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT 120
Query: 121 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK 180
EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
Sbjct: 121 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK 180
Query: 181 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE 240
KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE
Sbjct: 181 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE 240
Query: 241 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF 300
KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
Sbjct: 241 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF 300
Query: 301 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF 360
SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
Sbjct: 301 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF 360
Query: 361 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE 420
TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
Sbjct: 361 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE 420
Query: 421 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD 480
ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
Sbjct: 421 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD 480
Query: 481 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG 531
LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
Sbjct: 481 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG 531
>gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo
sapiens]
Length = 486
Score = 921 bits (2381), Expect = 0.0
Identities = 486/531 (91%), Positives = 486/531 (91%), Gaps = 45/531 (8%)
Query: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60
MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
Sbjct: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60
Query: 61 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT 120
NVLLHEM GLHPRIIT
Sbjct: 61 NVLLHEM---------------------------------------------GLHPRIIT 75
Query: 121 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK 180
EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
Sbjct: 76 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK 135
Query: 181 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE 240
KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE
Sbjct: 136 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE 195
Query: 241 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF 300
KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
Sbjct: 196 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF 255
Query: 301 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF 360
SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
Sbjct: 256 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF 315
Query: 361 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE 420
TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
Sbjct: 316 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE 375
Query: 421 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD 480
ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
Sbjct: 376 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD 435
Query: 481 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG 531
LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
Sbjct: 436 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG 486
>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
Length = 530
Score = 901 bits (2329), Expect = 0.0
Identities = 455/530 (85%), Positives = 500/530 (94%)
Query: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60
MAA+K +N KAEVARA+AALAVNI AARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
Sbjct: 1 MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60
Query: 61 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT 120
NVLL EMQIQHPTASLIAKVATAQDD+TGDGTTSNVLIIGELLKQADLYISEGLHPRII
Sbjct: 61 NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA 120
Query: 121 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK 180
EGFEAAK KAL+ LEEVKV++EM R+ L+DVARTSL+TKVHAELADVLTE VVDS+LA++
Sbjct: 121 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR 180
Query: 181 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE 240
+ PIDLFM+EIMEMKHK TDT LI+GLVLDHGARHPDMKKRVEDA+IL CNVSLEYE
Sbjct: 181 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE 240
Query: 241 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF 300
KTEVNSGFFYK+AEE+EKLVKAERKFIEDRV+KII+LK KVC S+KGFVVINQKGIDPF
Sbjct: 241 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF 300
Query: 301 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF 360
SLD+L+K GIVALRRAKRRNMERL+LACGG+A+NSF+DL+ DCLGHAGLVYEYTLGEEKF
Sbjct: 301 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF 360
Query: 361 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE 420
TFIE+C NP SVTLL+KGPNKHTLTQ+KDA+RDGLRA+KNAI+DGC+VPGAGA+EVAMAE
Sbjct: 361 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE 420
Query: 421 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD 480
AL+ +K S+KGRA+LGVQAFADALLIIPKVLAQN+G+D QETLVK+QAEH ES QLVGVD
Sbjct: 421 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD 480
Query: 481 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 530
LNTGEPMVAA+ GVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
Sbjct: 481 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 530
>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
sapiens]
Length = 545
Score = 265 bits (678), Expect = 6e-71
Identities = 148/507 (29%), Positives = 289/507 (57%), Gaps = 16/507 (3%)
Query: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82
NI+AA+ + D++RT LGPK MKML+ G I +T DGN +L E+Q+QHP A + +++
Sbjct: 26 NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISR 85
Query: 83 AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSRE 142
QD+ GDGTTS +++ GE+L A+ ++ + +HP ++ + A + + L+++ + +
Sbjct: 86 TQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVD 145
Query: 143 M-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD---EPIDL-FMIEIMEMK 197
+ D + ++++ +S+ TK + + + +D++ ++ ++ + ID+ + ++
Sbjct: 146 ISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIP 205
Query: 198 HKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEERE 257
D+ ++RG++++ HP M++ +++ I+ + SLEY+K E + E+
Sbjct: 206 GGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFT 265
Query: 258 KLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAK 317
++++ E ++I+ + II+LK VVI +KGI + L + I A+RR +
Sbjct: 266 RILQMEEEYIQQLCEDIIQLKPD---------VVITEKGISDLAQHYLMRANITAIRRVR 316
Query: 318 RRNMERLTLACGGVALNSFDDLSPDCLG-HAGLVYEYTLGEEKFTFIEKCNNPRSVTLLI 376
+ + R+ ACG ++ ++L D +G AGL+ +G+E FTFI C +P++ T+L+
Sbjct: 317 KTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILL 376
Query: 377 KGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLG 436
+G +K L++++ ++D ++ +N + D +VPG GA E+A+A AL + ++ G Q
Sbjct: 377 RGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWP 436
Query: 437 VQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS-ESGQLVGVDLNTGEPMVAAEVGVW 495
+A A AL +IP+ L QN G L ++A+H+ E+ + GV+ TG + E+G+W
Sbjct: 437 YRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIW 496
Query: 496 DNYCVKKQLLHSCTVIATNILLVDEIM 522
+ VK Q + A +L +D+I+
Sbjct: 497 EPLAVKLQTYKTAVETAVLLLRIDDIV 523
>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
sapiens]
Length = 544
Score = 264 bits (675), Expect = 1e-70
Identities = 151/507 (29%), Positives = 290/507 (57%), Gaps = 17/507 (3%)
Query: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82
NI+AA+ + D++RT LGPK MKML+ G I +T DGN +L E+Q+QHP A + +++
Sbjct: 26 NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISR 85
Query: 83 AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSRE 142
QD+ GDGTTS V+I+GE+L A+ ++ + +HP ++ + A + + L+++ + +
Sbjct: 86 TQDEEVGDGTTS-VIILGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVD 144
Query: 143 M-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD---EPIDLFMIEIME-MK 197
+ D + ++++ +S+ TK + + + +D++ ++ ++ + ID+ +E +
Sbjct: 145 ISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIP 204
Query: 198 HKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEERE 257
D+ ++RG++++ HP M++ +++ I+ + SLEY+K E + E+
Sbjct: 205 GGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFT 264
Query: 258 KLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAK 317
++++ E ++I+ + II+LK V VI +KGI + L + I A+RR +
Sbjct: 265 RILQMEEEYIQQLCEDIIQLKPDV---------VITEKGISDLAQHYLMRANITAIRRVR 315
Query: 318 RRNMERLTLACGGVALNSFDDLSPDCLGH-AGLVYEYTLGEEKFTFIEKCNNPRSVTLLI 376
+ + R+ ACG ++ ++L D +G AGL+ +G+E FTFI C +P++ T+L+
Sbjct: 316 KTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILL 375
Query: 377 KGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLG 436
+G +K L++++ ++D ++ +N + D +VPG GA E+A+A AL + ++ G Q
Sbjct: 376 RGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWP 435
Query: 437 VQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS-ESGQLVGVDLNTGEPMVAAEVGVW 495
+A A AL +IP+ L QN G L ++A+H+ E+ + GV+ TG + E+G+W
Sbjct: 436 YRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIW 495
Query: 496 DNYCVKKQLLHSCTVIATNILLVDEIM 522
+ VK Q + A +L +D+I+
Sbjct: 496 EPLAVKLQTYKTAVETAVLLLRIDDIV 522
>gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo
sapiens]
Length = 541
Score = 250 bits (639), Expect = 2e-66
Identities = 164/519 (31%), Positives = 276/519 (53%), Gaps = 22/519 (4%)
Query: 19 ALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIA 78
AL +I AA+ + + +RT+LGP G KM+V GD+ +T DG +L M + H A L+
Sbjct: 33 ALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMV 92
Query: 79 KVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVK 138
+++ +QDD GDGTT V++ G LL++A+ + G+HP I +G+E A A++ L+++
Sbjct: 93 ELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKIS 152
Query: 139 VSREM---DRETLIDVARTSLRTKV----HAELADVLTEAVVDSILAIKKQDEPIDLFMI 191
S + D E LI A+T+L +KV H ++A++ AV+ ++ ++++D +D +I
Sbjct: 153 DSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVL-TVADMERRD--VDFELI 209
Query: 192 EIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYK 251
++ DT LI+G+++D HP M K+VEDA I E K +
Sbjct: 210 KVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVT 269
Query: 252 SAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIV 311
S E+ + L K E++ E+ +++I E + I Q G D + L + +
Sbjct: 270 SVEDYKALQKYEKEKFEEMIQQIKETGAN---------LAICQWGFDDEANHLLLQNNLP 320
Query: 312 ALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLG--EEKFTFIEKCNNP 369
A+R +E + +A GG + F +L+ + LG AGLV E + G ++K IE+C N
Sbjct: 321 AVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNS 380
Query: 370 RSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSV 429
R+VT+ I+G NK + + K ++ D L ++N I D VV G GA E++ A A+ +
Sbjct: 381 RAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC 440
Query: 430 KGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEH-SESGQLVGVDLNTGEPMV 488
Q ++AFADAL +IP L++NSG + +T+ +++A E +G+D
Sbjct: 441 PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTND 500
Query: 489 AAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMS 527
+ V + KKQ + T + IL +D+I + G S
Sbjct: 501 MKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGES 539
>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
Length = 556
Score = 242 bits (618), Expect = 5e-64
Identities = 150/521 (28%), Positives = 279/521 (53%), Gaps = 29/521 (5%)
Query: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82
N+ AA + ++++++LGP G KMLV GD+ +T DG +L ++++HP A ++ ++A
Sbjct: 21 NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80
Query: 83 AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEE--VKVS 140
QD GDGTTS V+I ELLK AD + + +HP + G+ A ++A++++ E + +
Sbjct: 81 LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140
Query: 141 REMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD---EP-IDLFMIEIMEM 196
E+ R+ LI+ A+TS+ +K+ D VVD++LAIK D +P + + I++
Sbjct: 141 DELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKA 200
Query: 197 KHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEER 256
+S+ ++ LI G L+ M KR+ +A I + SL+ K ++ E+
Sbjct: 201 HGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKL 260
Query: 257 EKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRA 316
+++ + E ++R++KI+ + V++ GID L + G +A+RR
Sbjct: 261 DQIRQRESDITKERIQKIL---------ATGANVILTTGGIDDMCLKYFVEAGAMAVRRV 311
Query: 317 KRRNMERLTLACGGVALNSFDDLSPD------CLGHAGLVYEYTLGEEKFTFIEKCNNPR 370
+R+++R+ A G L++ +L + LG A V + + +++ I+
Sbjct: 312 LKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKART 371
Query: 371 SVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVK 430
S +++++G N +++ ++ D L VK ++ VVPG GAVE A++ L + S+
Sbjct: 372 SASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMG 431
Query: 431 GRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESG--------QLVGVDLN 482
R QL + FA +LL+IP LA N+ D + + K++A H+E+ + +G+DL+
Sbjct: 432 SREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLS 491
Query: 483 TGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMR 523
G+P + GV++ VK + L T A IL +D++++
Sbjct: 492 NGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532
>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
sapiens]
Length = 543
Score = 236 bits (602), Expect = 4e-62
Identities = 148/518 (28%), Positives = 264/518 (50%), Gaps = 20/518 (3%)
Query: 20 LAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAK 79
L NISA + + + +RT LGP+G K++V G G ++ DG +L + + HP A +
Sbjct: 22 LVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVHPAAKTLVD 81
Query: 80 VATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEV-- 137
+A +QD GDGTTS L+ E LKQ Y+ EGLHP+II F A + A+ ++E+
Sbjct: 82 IAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAV 141
Query: 138 ---KVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEIM 194
K + R+ L A T+L +K+ ++ + VVD+++ + D+ + L MI I
Sbjct: 142 TVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMML---DDLLQLKMIGIK 198
Query: 195 EMKHKSETDTSLIRGLVLDHGARHPDMK---KRVEDAYILTCNVSLEYEKTEVNSGFFYK 251
+++ + D+ L+ G+ + + K+ + I NV LE + + N+
Sbjct: 199 KVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEIRVH 258
Query: 252 SAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIV 311
+ E+ + +V AE + D+++KI KV V+++ I + + +
Sbjct: 259 TVEDYQAIVDAEWNILYDKLEKIHHSGAKV---------VLSKLPIGDVATQYFADRDMF 309
Query: 312 ALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRS 371
R +++R +ACGG S + LS D LG + E +G E++ F C ++
Sbjct: 310 CAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKT 369
Query: 372 VTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKG 431
T +++G + + + + ++ D + V+ AI + VV G GA+E+ +++ L + ++ G
Sbjct: 370 CTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPG 429
Query: 432 RAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAE 491
+ QL + A+A AL IIP+ L N+GFD L K++A H++ G GVD+N + E
Sbjct: 430 KQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFE 489
Query: 492 VGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSL 529
VW+ V+ L + + A I+ VDE ++ S++
Sbjct: 490 AFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTV 527
>gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
sapiens]
Length = 539
Score = 235 bits (600), Expect = 7e-62
Identities = 154/510 (30%), Positives = 272/510 (53%), Gaps = 20/510 (3%)
Query: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82
NISAA+ + D +RT+LGPKG KM+ G GD+ +T DG +L +MQ+ HP A ++ +++
Sbjct: 37 NISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSK 96
Query: 83 AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSRE 142
AQD GDGTTS V+I G LL + +G+HP II+E F+ A EK ++ L ++ E
Sbjct: 97 AQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVE 156
Query: 143 M-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAI--KKQDEPIDLFMIEIMEMKHK 199
+ DRETL++ A TSL +KV ++ + +L+ V++++ + +DL I+I++
Sbjct: 157 LSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGG 216
Query: 200 SETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKL 259
+ D L+ GLVL + + RVE A I L KT++++ + +++
Sbjct: 217 TIDDCELVEGLVLTQKVSNSGI-TRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRV 275
Query: 260 VKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGI-----DPFSLDALSKEGIVALR 314
++ ER +I + VK+I K+ C V++ QK I +L L+K I+ ++
Sbjct: 276 LREERAYILNLVKQI---KKTGCN------VLLIQKSILRDALSDLALHFLNKMKIMVIK 326
Query: 315 RAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTL-GEEKFTFIEKCNNP-RSV 372
+R ++E + G + D + D LG A L E L G K I C +P ++V
Sbjct: 327 DIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTV 386
Query: 373 TLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGR 432
T++++G NK + + + ++ D L ++ + ++ G GA E+ +A L ++ ++ G
Sbjct: 387 TIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGM 446
Query: 433 AQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEV 492
V+AFADA+ +IP LA+N+G + T+ +++ H++ + G+++ G E
Sbjct: 447 ESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEE 506
Query: 493 GVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
V V L T +IL +D+++
Sbjct: 507 LVVQPLLVSVSALTLATETVRSILKIDDVV 536
>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
sapiens]
Length = 507
Score = 224 bits (570), Expect = 2e-58
Identities = 128/472 (27%), Positives = 263/472 (55%), Gaps = 16/472 (3%)
Query: 58 KDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPR 117
+ GN+ ++Q+QHP A + +++ QD+ GDGTTS +++ GE+L A+ ++ + +HP
Sbjct: 23 QSGNINAAKIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 82
Query: 118 IITEGFEAAKEKALQFLEEVKVSREM-DRETLIDVARTSLRTKVHAELADVLTEAVVDSI 176
++ + A + + L+++ + ++ D + ++++ +S+ TK + + + +D++
Sbjct: 83 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 142
Query: 177 LAIKKQD---EPIDLFMIEIME-MKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILT 232
++ ++ + ID+ +E + D+ ++RG++++ HP M++ +++ I+
Sbjct: 143 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 202
Query: 233 CNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVI 292
+ SLEY+K E + E+ ++++ E ++I+ + II+LK V VI
Sbjct: 203 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDV---------VI 253
Query: 293 NQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGH-AGLVY 351
+KGI + L + I A+RR ++ + R+ ACG ++ ++L D +G AGL+
Sbjct: 254 TEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLE 313
Query: 352 EYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGA 411
+G+E FTFI C +P++ T+L++G +K L++++ ++D ++ +N + D +VPG
Sbjct: 314 IKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGG 373
Query: 412 GAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS 471
GA E+A+A AL + ++ G Q +A A AL +IP+ L QN G L ++A+H+
Sbjct: 374 GASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHT 433
Query: 472 -ESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
E+ + GV+ TG + E+G+W+ VK Q + A +L +D+I+
Sbjct: 434 QENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV 485
>gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
Length = 535
Score = 214 bits (545), Expect = 2e-55
Identities = 149/533 (27%), Positives = 271/533 (50%), Gaps = 24/533 (4%)
Query: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKL--TK 58
+A V A+ RA+ A + A + D++++ LGPKG K+L+S D L T
Sbjct: 6 LAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTN 65
Query: 59 DGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRI 118
DG +L + + +P A ++ ++ QDD GDGTTS ++ ELL++A+ I++ +HP+
Sbjct: 66 DGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQT 125
Query: 119 ITEGFEAAKEKALQFLEEVKVSREMD----RETLIDVARTSLRTKVHAELADVLTEAVVD 174
I G+ A + A + L V D R+ L+++A T+L +K+ D T+ V+
Sbjct: 126 IIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVE 185
Query: 175 SILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDH--GARHPDMKKRVEDAYILT 232
++L +K +L I I++ S D+ L G +LD G P KR+E+A IL
Sbjct: 186 AVLRLKGSG---NLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQP---KRIENAKILI 239
Query: 233 CNVSLEYEKTEV-NSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVV 291
N ++ +K ++ S S + ++ AE++ ++++V++I LK +
Sbjct: 240 ANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERI--LKHGIN-------CF 290
Query: 292 INQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVY 351
IN++ I + G++A+ A +ERL L GG ++FD LG L+
Sbjct: 291 INRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIE 350
Query: 352 EYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGA 411
E +GE+K + T++++G + L + + ++ D L + + D V G
Sbjct: 351 EVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGG 410
Query: 412 GAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS 471
G E+ MA A+ + G+ + ++++A AL ++P ++A N+G+D + + +++A HS
Sbjct: 411 GCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHS 470
Query: 472 ESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRA 524
E G+D+ G A +G+ +++ VK+Q+L S A IL VD I++A
Sbjct: 471 EGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKA 523
>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
sapiens]
Length = 548
Score = 176 bits (446), Expect = 5e-44
Identities = 134/514 (26%), Positives = 232/514 (45%), Gaps = 18/514 (3%)
Query: 17 QAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASL 76
+ A+ NI A + L RT GP G KM+++ + +T D +L E+++QHP A +
Sbjct: 26 EEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKM 85
Query: 77 IAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEE 136
I + Q+ GDGT ++ G LL+ A+ + GL + EG+E A KA + L
Sbjct: 86 IVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPN 145
Query: 137 V---KVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEI 193
+ D + + + RTS+ +K + L + + + ++I ++ I +
Sbjct: 146 LVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEV-FLAKLIAQACVSIFPDSGHFNVDNIRV 204
Query: 194 MEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSA 253
++ + +S++ G+V V+DA I + + TE K+A
Sbjct: 205 CKILGSGISSSSVLHGMVFKKETEGDVTS--VKDAKIAVYSCPFDGMITETKGTVLIKTA 262
Query: 254 EEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVAL 313
EE K E ++ +VK I D+ VV K D +L +K I+ +
Sbjct: 263 EELMNFSKGEENLMDAQVKAI--------ADTGANVVVTGGKVAD-MALHYANKYNIMLV 313
Query: 314 RRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSV- 372
R + ++ RL G AL + +GH VY +G+ + + ++
Sbjct: 314 RLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAIS 373
Query: 373 TLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGR 432
T++++G + + I+ AV DG+ K D +VPG GA E+ +A+ + + + G
Sbjct: 374 TIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGL 433
Query: 433 AQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMV--AA 490
Q ++ FA+A IP+ LA+NSG E + K+ A H E + VG+D+ P V
Sbjct: 434 EQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDML 493
Query: 491 EVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRA 524
E G+ D Y K + T A +L VD+I+ A
Sbjct: 494 EAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMA 527
>gi|57863259 T-complex protein 1 isoform b [Homo sapiens]
Length = 401
Score = 142 bits (357), Expect = 1e-33
Identities = 100/388 (25%), Positives = 191/388 (49%), Gaps = 31/388 (7%)
Query: 156 LRTKVHAELADVLTEAVVDSILAIKKQD------EPIDLFMIEIMEMKHKSETDTSLIRG 209
+ +K+ D VVD++LAIK D P++ + I++ +S+ ++ LI G
Sbjct: 1 MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVN--SVNILKAHGRSQMESMLISG 58
Query: 210 LVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIED 269
L+ M KR+ +A I + SL+ K ++ E+ +++ + E ++
Sbjct: 59 YALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKE 118
Query: 270 RVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACG 329
R++KI+ V ++ GID L + G +A+RR +R+++R+ A G
Sbjct: 119 RIQKILATGANV---------ILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASG 169
Query: 330 GVALNSFDDLSPD------CLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHT 383
L++ +L + LG A V + + +++ I+ S +++++G N
Sbjct: 170 ATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFM 229
Query: 384 LTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADA 443
+++ ++ D L VK ++ VVPG GAVE A++ L + S+ R QL + FA +
Sbjct: 230 CDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARS 289
Query: 444 LLIIPKVLAQNSGFDLQETLVKIQAEHSESG--------QLVGVDLNTGEPMVAAEVGVW 495
LL+IP LA N+ D + + K++A H+E+ + +G+DL+ G+P + GV+
Sbjct: 290 LLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVF 349
Query: 496 DNYCVKKQLLHSCTVIATNILLVDEIMR 523
+ VK + L T A IL +D++++
Sbjct: 350 EPTIVKVKSLKFATEAAITILRIDDLIK 377
>gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo
sapiens]
Length = 339
Score = 133 bits (334), Expect = 5e-31
Identities = 83/307 (27%), Positives = 153/307 (49%), Gaps = 9/307 (2%)
Query: 223 KRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVC 282
K+ + I NV LE + + N+ + E+ + +V AE + D+++KI KV
Sbjct: 26 KKYHNPKIALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKV- 84
Query: 283 GDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPD 342
V+++ I + + + R +++R +ACGG S + LS D
Sbjct: 85 --------VLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSAD 136
Query: 343 CLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAI 402
LG + E +G E++ F C ++ T +++G + + + + ++ D + V+ AI
Sbjct: 137 VLGRCQVFEETQIGGERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAI 196
Query: 403 DDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQET 462
+ VV G GA+E+ +++ L + ++ G+ QL + A+A AL IIP+ L N+GFD
Sbjct: 197 KNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNI 256
Query: 463 LVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
L K++A H++ G GVD+N + E VW+ V+ L + + A I+ VDE +
Sbjct: 257 LNKLRARHAQGGTWYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETI 316
Query: 523 RAGMSSL 529
+ S++
Sbjct: 317 KNPRSTV 323
>gi|7657253 T-complex protein 1 [Homo sapiens]
Length = 557
Score = 130 bits (327), Expect = 3e-30
Identities = 124/509 (24%), Positives = 215/509 (42%), Gaps = 16/509 (3%)
Query: 20 LAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAK 79
L +++A + L V+R GP G K LV+ G+ T +L ++++HP A L+ +
Sbjct: 33 LLSSLAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLRE 92
Query: 80 VATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKV 139
Q + +GDGT VL+ LL+QA+ + GL + E + A + L L + +
Sbjct: 93 AGQTQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVLATLPSLAI 152
Query: 140 SREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEIMEMKHK 199
E + + T + + D LT+ V + AIK+ D + + +
Sbjct: 153 QSLGPLEDPSWALHSVMNTHTLSPM-DHLTKLVAHACWAIKELDGSFKPERVGVCALPGG 211
Query: 200 SETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKL 259
+ D+ L+ GL + G M + A + + S + +
Sbjct: 212 TLEDSCLLPGLAIS-GKLCGQMATVLSGARVALFACPFGPAHPNAPATARLSSPADLAQF 270
Query: 260 VKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRR 319
K + +E +V ++ V VV+ + +D +L K GIV ++
Sbjct: 271 SKGSDQLLEKQVGQLAAAGINVA-------VVLGE--VDEETLTLADKYGIVVIQARSWM 321
Query: 320 NMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIE-KCNNPRSVTLLIKG 378
+ L+ L L P G VY LG+ E +C ++T++++G
Sbjct: 322 EIIYLSEVLDTPLLPRL--LPPQRPGKCQRVYRQELGDGLAVVFEWECTGTPALTVVLRG 379
Query: 379 PNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQ 438
L + AV G+ A D ++PGAGA E+A+A+ L ++G +
Sbjct: 380 ATTQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMALAKMLSDKGSRLEGPSGPAFL 439
Query: 439 AFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNY 498
AFA AL +PK LA+N+G + + + ++ H L+GV T + A+ GVWD
Sbjct: 440 AFAWALKYLPKTLAENAGLAVSDVMAEMSGVHQGGNLLMGV--GTEGIINVAQEGVWDTL 497
Query: 499 CVKKQLLHSCTVIATNILLVDEIMRAGMS 527
VK Q + + ++ VDEI+ A S
Sbjct: 498 IVKAQGFRAVAEVVLQLVTVDEIVVAKKS 526
>gi|41399285 chaperonin [Homo sapiens]
Length = 573
Score = 61.6 bits (148), Expect = 2e-09
Identities = 123/571 (21%), Positives = 234/571 (40%), Gaps = 101/571 (17%)
Query: 19 ALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPT----A 74
A A+ + L D + +GPKG ++ G K+TKDG + + ++ A
Sbjct: 36 ARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGA 95
Query: 75 SLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFL 134
L+ VA ++ GDGTT+ ++ + K+ IS+G +P I G A + + L
Sbjct: 96 KLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAEL 155
Query: 135 EEVKVSREMDR-ETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEI 193
+ K S+ + E + VA ++ E+ +++++ A+KK +I +
Sbjct: 156 K--KQSKPVTTPEEIAQVA--TISANGDKEIGNIISD-------AMKKVGRK---GVITV 201
Query: 194 MEMKHKSETDTSLIRGLVLDHGARHP-------DMKKRVEDAYILTCNVSLEYEKTEVNS 246
+ K ++ + +I G+ D G P K +DAY+L + +++S
Sbjct: 202 KDGKTLND-ELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVL-------LSEKKISS 253
Query: 247 GFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALS 306
+S ++ A R K ++ + V G++ +V+N+ + + A+
Sbjct: 254 ---IQSIVPALEIANAHR-------KPLVIIAEDVDGEA-LSTLVLNRLKVG-LQVVAVK 301
Query: 307 KEGIVALRRAKRRNMERLTLACGGVALN------SFDDLSPDCLGHAGLVY--------- 351
G R+ + ++M +A GG + +D+ P LG G V
Sbjct: 302 APGFGDNRKNQLKDM---AIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLL 358
Query: 352 ----EYTLGEEKFTFI-------------EKCNNPRS------VTLLIKGPNKHTLTQIK 388
+ E++ I EK N + L + G + + + K
Sbjct: 359 KGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKK 418
Query: 389 DAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIP 448
D V D L A + A+++G +V G G + AL P+ + + ++G++ L I
Sbjct: 419 DRVTDALNATRAAVEEG-IVLGGGCALLRCIPALDSLTPANEDQ-KIGIEIIKRTLKIPA 476
Query: 449 KVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWD-NYCVKKQLLHS 507
+A+N+G + + KI SE VG D G+ + E G+ D V+ LL +
Sbjct: 477 MTIAKNAGVEGSLIVEKIMQSSSE----VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDA 532
Query: 508 ---CTVIATNILLVDEIMR----AGMSSLKG 531
+++ T ++V EI + GM ++ G
Sbjct: 533 AGVASLLTTAEVVVTEIPKEEKDPGMGAMGG 563
>gi|31542947 chaperonin [Homo sapiens]
Length = 573
Score = 61.6 bits (148), Expect = 2e-09
Identities = 123/571 (21%), Positives = 234/571 (40%), Gaps = 101/571 (17%)
Query: 19 ALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPT----A 74
A A+ + L D + +GPKG ++ G K+TKDG + + ++ A
Sbjct: 36 ARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGA 95
Query: 75 SLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFL 134
L+ VA ++ GDGTT+ ++ + K+ IS+G +P I G A + + L
Sbjct: 96 KLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAEL 155
Query: 135 EEVKVSREMDR-ETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEI 193
+ K S+ + E + VA ++ E+ +++++ A+KK +I +
Sbjct: 156 K--KQSKPVTTPEEIAQVA--TISANGDKEIGNIISD-------AMKKVGRK---GVITV 201
Query: 194 MEMKHKSETDTSLIRGLVLDHGARHP-------DMKKRVEDAYILTCNVSLEYEKTEVNS 246
+ K ++ + +I G+ D G P K +DAY+L + +++S
Sbjct: 202 KDGKTLND-ELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVL-------LSEKKISS 253
Query: 247 GFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALS 306
+S ++ A R K ++ + V G++ +V+N+ + + A+
Sbjct: 254 ---IQSIVPALEIANAHR-------KPLVIIAEDVDGEA-LSTLVLNRLKVG-LQVVAVK 301
Query: 307 KEGIVALRRAKRRNMERLTLACGGVALN------SFDDLSPDCLGHAGLVY--------- 351
G R+ + ++M +A GG + +D+ P LG G V
Sbjct: 302 APGFGDNRKNQLKDM---AIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLL 358
Query: 352 ----EYTLGEEKFTFI-------------EKCNNPRS------VTLLIKGPNKHTLTQIK 388
+ E++ I EK N + L + G + + + K
Sbjct: 359 KGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKK 418
Query: 389 DAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIP 448
D V D L A + A+++G +V G G + AL P+ + + ++G++ L I
Sbjct: 419 DRVTDALNATRAAVEEG-IVLGGGCALLRCIPALDSLTPANEDQ-KIGIEIIKRTLKIPA 476
Query: 449 KVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWD-NYCVKKQLLHS 507
+A+N+G + + KI SE VG D G+ + E G+ D V+ LL +
Sbjct: 477 MTIAKNAGVEGSLIVEKIMQSSSE----VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDA 532
Query: 508 ---CTVIATNILLVDEIMR----AGMSSLKG 531
+++ T ++V EI + GM ++ G
Sbjct: 533 AGVASLLTTAEVVVTEIPKEEKDPGMGAMGG 563
>gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
Length = 723
Score = 46.6 bits (109), Expect = 6e-05
Identities = 26/98 (26%), Positives = 50/98 (51%), Gaps = 4/98 (4%)
Query: 7 LNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHE 66
L+ A +AAL V A L+ ++ +GP+G + G++ L+++G LL
Sbjct: 2 LSSMAAAGSVKAALQV----AEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEA 57
Query: 67 MQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLK 104
+ ++HP A +I ++ TGDG + ++ + LL+
Sbjct: 58 LHLEHPIARMIVDCVSSHLKKTGDGAKTFIIFLCHLLR 95
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 36.2 bits (82), Expect = 0.077
Identities = 38/153 (24%), Positives = 66/153 (43%), Gaps = 20/153 (13%)
Query: 127 KEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPI 186
+E+ L E E DRET +V L + E D + E+ + +KKQ +
Sbjct: 1499 REQKLTVQREQIRELEKDRETQRNVLEHQL---LELEKKDQMIESQRGQVQDLKKQLVTL 1555
Query: 187 DLFMIEIMEMKHKSETDTSLIRGLVLDHGARHP----------DMKKRVEDAYILTCNVS 236
+ +E+ E HK E LI+ L G R D+++R ++ S
Sbjct: 1556 ECLALELEENHHKMECQQKLIKEL---EGQRETQRVALTHLTLDLEERSQELQA----QS 1608
Query: 237 LEYEKTEVNSGFFYKSAEEREKLVKAERKFIED 269
+ E +S + +ER++ VK++R+ IE+
Sbjct: 1609 SQIHDLESHSTVLARELQERDQEVKSQREQIEE 1641
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 34.7 bits (78), Expect = 0.22
Identities = 47/197 (23%), Positives = 81/197 (41%), Gaps = 43/197 (21%)
Query: 117 RIITEGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAEL-ADVLTEAVVDS 175
R+ E E KE+ LQ E++K ++ RE L + +T L K ++ + L E D
Sbjct: 611 RLRQEAKEREKERILQEHEQIK--KKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDF 668
Query: 176 ILA----------------IKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHP 219
I+A +K Q++ ID F + K + LI+ + +
Sbjct: 669 IMAKQVEQLEKEKKELQERLKNQEKKIDYFE------RAKRLEEIPLIKSAYEEQRIKDM 722
Query: 220 DMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEER----------------EKLVKAE 263
D+ ++ E+ I T + LE EK + + E+R EKL + E
Sbjct: 723 DLWEQQEEERITT--MQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFE 780
Query: 264 RKFIEDRVKKIIELKRK 280
+ E+R ++ E KR+
Sbjct: 781 ERLAEERHNRLEERKRQ 797
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 32.7 bits (73), Expect = 0.85
Identities = 48/215 (22%), Positives = 92/215 (42%), Gaps = 44/215 (20%)
Query: 124 EAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVD----SILAI 179
+A + A +FLEE+++S E+ R+ ID+ ++ H D+ V+ + +
Sbjct: 2507 DALQAVASRFLEEIEMSEEI-RDGCIDMCKS-----FHTSTIDLSKSFFVELQRYNYVTP 2560
Query: 180 KKQDEPIDLFMI-------EIMEMK-------HKSETDTSLIRGLVLDHGARHPDMK--- 222
E I F + E+M+MK K ++ +S + + ++ A HP +K
Sbjct: 2561 TSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVAS 2620
Query: 223 KRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVC 282
K V++ I+ S+E KT EK+VKA+ ++ +K + C
Sbjct: 2621 KEVDEMMIMIEKESVEVAKT--------------EKIVKADETIANEQAMASKAIKDE-C 2665
Query: 283 GDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAK 317
G + I + + +LD L+ + I ++ K
Sbjct: 2666 DADLAGALPILESAL--AALDTLTAQDITVVKSMK 2698
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 32.7 bits (73), Expect = 0.85
Identities = 33/148 (22%), Positives = 71/148 (47%), Gaps = 5/148 (3%)
Query: 138 KVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFM-IEIMEM 196
K+ R+++ TL A + K HA+ L E + D++ +K++ E M +EI ++
Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQI-DNLQRVKQKLEKEKSEMKMEIDDL 1237
Query: 197 KHKSETDTSL---IRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSA 253
ET + + + + ++K + E+ L +++ + + + SG F +
Sbjct: 1238 ASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL 1297
Query: 254 EEREKLVKAERKFIEDRVKKIIELKRKV 281
+E+E LV + + ++I ELKR++
Sbjct: 1298 DEKEALVSQLSRGKQAFTQQIEELKRQL 1325
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 32.7 bits (73), Expect = 0.85
Identities = 33/148 (22%), Positives = 71/148 (47%), Gaps = 5/148 (3%)
Query: 138 KVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFM-IEIMEM 196
K+ R+++ TL A + K HA+ L E + D++ +K++ E M +EI ++
Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQI-DNLQRVKQKLEKEKSEMKMEIDDL 1237
Query: 197 KHKSETDTSL---IRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSA 253
ET + + + + ++K + E+ L +++ + + + SG F +
Sbjct: 1238 ASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL 1297
Query: 254 EEREKLVKAERKFIEDRVKKIIELKRKV 281
+E+E LV + + ++I ELKR++
Sbjct: 1298 DEKEALVSQLSRGKQAFTQQIEELKRQL 1325
>gi|70980531 GGA binding partner [Homo sapiens]
Length = 441
Score = 32.7 bits (73), Expect = 0.85
Identities = 40/174 (22%), Positives = 82/174 (47%), Gaps = 25/174 (14%)
Query: 118 IITEGFEAAKEK-ALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSI 176
++ +GF KE+ A+ F + K +E ++ L D+ + H L+ ++ E
Sbjct: 168 VLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAG-----HEALSIIVDEYKALLQ 222
Query: 177 LAIKKQDEPIDLFMIEIMEMK-HKSETDTSLIRGLVLDHGARHPDM-KKRVEDAYILTCN 234
++K+Q E I+ I +E + HK E + +L+ ++ K+++++A I
Sbjct: 223 SSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALI---- 278
Query: 235 VSLEYEKTEVNSGFFYKSAEE-----REKLVKA---ERKFIEDRVKKIIELKRK 280
++++ K EE +E LV A E++ ++D V K++E +RK
Sbjct: 279 -----QQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERK 327
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 32.7 bits (73), Expect = 0.85
Identities = 64/307 (20%), Positives = 130/307 (42%), Gaps = 47/307 (15%)
Query: 120 TEGFEAAKEKALQFLEEVKVS------REMDRETLIDVARTSLRTKVHAELA----DVLT 169
+ F A E+ Q L +VK R ++ +++A + ++ E ++LT
Sbjct: 736 SSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLT 795
Query: 170 EAVVDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGL----------VLDHGARHP 219
E + + K +D I++ E+ +++ + ++LIR L VL+ R
Sbjct: 796 EQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVR 855
Query: 220 DMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKR 279
+ +VE+ LE K + + E+++ V+ ++ IE++ +++ E+
Sbjct: 856 HISSKVEELSQALSQKELEITKMD-------QLLLEKKRDVETLQQTIEEKDQQVTEISF 908
Query: 280 KVCGDSDKGFVVINQKGIDPFSLDA---LSKEGIVALRR---AKRRNMERLTLACGGVAL 333
+ + V +N+ + FSL KE + L R AK+ +E G+
Sbjct: 909 SM----TEKMVQLNE---EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQ 961
Query: 334 NSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRD 393
N +D++SP AG + + L + +F ++K N R L N+ L Q + +
Sbjct: 962 N-YDEMSP-----AGQISKEEL-QHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEE 1014
Query: 394 GLRAVKN 400
L +K+
Sbjct: 1015 ELANLKD 1021
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 32.3 bits (72), Expect = 1.1
Identities = 30/165 (18%), Positives = 76/165 (46%), Gaps = 21/165 (12%)
Query: 128 EKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPID 187
EK L+++EE+ + + + +D+A+ K + L +++ ++I+ + KQ E ++
Sbjct: 145 EKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLN 204
Query: 188 LFMIEIMEMKHKSETD-------------TSLIRGLVLDHGARHPDMKKRVEDAYILTCN 234
+ +++E + + + +L + +L+ R +K ++
Sbjct: 205 V-KCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID------ 257
Query: 235 VSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKR 279
SL ++ E++S K +E++VK + F E+ + + EL +
Sbjct: 258 -SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDK 301
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 32.3 bits (72), Expect = 1.1
Identities = 30/165 (18%), Positives = 76/165 (46%), Gaps = 21/165 (12%)
Query: 128 EKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPID 187
EK L+++EE+ + + + +D+A+ K + L +++ ++I+ + KQ E ++
Sbjct: 232 EKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLN 291
Query: 188 LFMIEIMEMKHKSETD-------------TSLIRGLVLDHGARHPDMKKRVEDAYILTCN 234
+ +++E + + + +L + +L+ R +K ++
Sbjct: 292 V-KCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID------ 344
Query: 235 VSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKR 279
SL ++ E++S K +E++VK + F E+ + + EL +
Sbjct: 345 -SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDK 388
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 32.3 bits (72), Expect = 1.1
Identities = 30/165 (18%), Positives = 76/165 (46%), Gaps = 21/165 (12%)
Query: 128 EKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPID 187
EK L+++EE+ + + + +D+A+ K + L +++ ++I+ + KQ E ++
Sbjct: 216 EKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLN 275
Query: 188 LFMIEIMEMKHKSETD-------------TSLIRGLVLDHGARHPDMKKRVEDAYILTCN 234
+ +++E + + + +L + +L+ R +K ++
Sbjct: 276 V-KCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID------ 328
Query: 235 VSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKR 279
SL ++ E++S K +E++VK + F E+ + + EL +
Sbjct: 329 -SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDK 372
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 32.3 bits (72), Expect = 1.1
Identities = 30/165 (18%), Positives = 76/165 (46%), Gaps = 21/165 (12%)
Query: 128 EKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPID 187
EK L+++EE+ + + + +D+A+ K + L +++ ++I+ + KQ E ++
Sbjct: 231 EKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLN 290
Query: 188 LFMIEIMEMKHKSETD-------------TSLIRGLVLDHGARHPDMKKRVEDAYILTCN 234
+ +++E + + + +L + +L+ R +K ++
Sbjct: 291 V-KCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID------ 343
Query: 235 VSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKR 279
SL ++ E++S K +E++VK + F E+ + + EL +
Sbjct: 344 -SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDK 387
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 32.3 bits (72), Expect = 1.1
Identities = 36/151 (23%), Positives = 75/151 (49%), Gaps = 11/151 (7%)
Query: 126 AKEKALQFLEEVKVSREMDRETLIDVART-SLRTKVHAELADVLTEAVVDSILAIKKQDE 184
++E+ L+ L ++ +E+ ET +VA+ SLR + EL + + + DS+ A +++ +
Sbjct: 1192 SQEQILEILRFIRREKEI-AETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQ 1250
Query: 185 PIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVE-DAYILTCNV-SLEYEKT 242
M + E+ K+ET +V++ + K+R+E D + V LE +
Sbjct: 1251 VTAKTMAQHEELMKKTET-----MNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDIL 1305
Query: 243 EVNSGFFYKSAEEREKLVKAERKFIEDRVKK 273
+ E+ +++AE+K +E+ VK+
Sbjct: 1306 PLQEA--NAELSEKSGMLQAEKKLLEEDVKR 1334
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,835,534
Number of Sequences: 37866
Number of extensions: 678325
Number of successful extensions: 1945
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 1869
Number of HSP's gapped (non-prelim): 76
length of query: 531
length of database: 18,247,518
effective HSP length: 107
effective length of query: 424
effective length of database: 14,195,856
effective search space: 6019042944
effective search space used: 6019042944
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.