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Search of human proteins with 4502565
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502565 calpain, small subunit 1 [Homo sapiens]
(268 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502565 calpain, small subunit 1 [Homo sapiens] 552 e-157
gi|51599151 calpain, small subunit 1 [Homo sapiens] 552 e-157
gi|14161692 calpain small subunit 2 [Homo sapiens] 338 3e-93
gi|47078247 calpain 3 isoform f [Homo sapiens] 224 5e-59
gi|4557405 calpain 3 isoform a [Homo sapiens] 224 5e-59
gi|27765072 calpain 3 isoform b [Homo sapiens] 224 5e-59
gi|27765076 calpain 3 isoform d [Homo sapiens] 224 5e-59
gi|27765074 calpain 3 isoform c [Homo sapiens] 223 1e-58
gi|27765080 calpain 3 isoform e [Homo sapiens] 196 1e-50
gi|27765078 calpain 3 isoform e [Homo sapiens] 196 1e-50
gi|12408656 calpain 1, large subunit [Homo sapiens] 190 1e-48
gi|157389005 calpain 2 isoform 1 [Homo sapiens] 180 1e-45
gi|225703100 calpain 2 isoform 2 [Homo sapiens] 180 1e-45
gi|7705383 calpain 9 isoform 2 [Homo sapiens] 165 4e-41
gi|5729758 calpain 9 isoform 1 [Homo sapiens] 165 4e-41
gi|215490104 calpain 11 [Homo sapiens] 156 2e-38
gi|221554549 calpain 8 [Homo sapiens] 150 9e-37
gi|4507207 sorcin isoform a [Homo sapiens] 106 2e-23
gi|38679884 sorcin isoform b [Homo sapiens] 105 4e-23
gi|41152101 calpain 13 [Homo sapiens] 102 5e-22
gi|6912388 grancalcin, EF-hand calcium binding protein [Homo sap... 98 9e-21
gi|38707981 calpain 12 [Homo sapiens] 96 3e-20
gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens] 88 9e-18
gi|223468608 calpain 14 [Homo sapiens] 85 6e-17
gi|7019485 programmed cell death 6 [Homo sapiens] 79 4e-15
gi|109452587 family with sequence similarity 98, member B isofor... 73 2e-13
gi|119395750 keratin 1 [Homo sapiens] 67 1e-11
gi|12056465 fibrillarin [Homo sapiens] 66 3e-11
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 66 3e-11
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 64 1e-10
>gi|4502565 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 552 bits (1422), Expect = e-157
Identities = 268/268 (100%), Positives = 268/268 (100%)
Query: 1 MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60
MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR
Sbjct: 1 MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60
Query: 61 ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL 120
ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL
Sbjct: 61 ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL 120
Query: 121 MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ 180
MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ
Sbjct: 121 MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ 180
Query: 181 FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF 240
FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF
Sbjct: 181 FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF 240
Query: 241 RAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
RAFKSLDKDGTGQIQVNIQEWLQLTMYS
Sbjct: 241 RAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
>gi|51599151 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 552 bits (1422), Expect = e-157
Identities = 268/268 (100%), Positives = 268/268 (100%)
Query: 1 MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60
MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR
Sbjct: 1 MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60
Query: 61 ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL 120
ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL
Sbjct: 61 ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL 120
Query: 121 MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ 180
MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ
Sbjct: 121 MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ 180
Query: 181 FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF 240
FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF
Sbjct: 181 FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF 240
Query: 241 RAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
RAFKSLDKDGTGQIQVNIQEWLQLTMYS
Sbjct: 241 RAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
>gi|14161692 calpain small subunit 2 [Homo sapiens]
Length = 248
Score = 338 bits (867), Expect = 3e-93
Identities = 172/269 (63%), Positives = 208/269 (77%), Gaps = 22/269 (8%)
Query: 1 MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60
MFL + L+G G LG LGGL GGGG GGG GG
Sbjct: 1 MFLAKALLEGADRG----------LGEALGGLF-------GGGGQRREGGGRNIGG---- 39
Query: 61 ILGGVISAISEAAA-QYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATE 119
I+GG+++ ISEAAA QY PEPPP + H++++EA+ESEEVR+FR+ F QLAG DMEV AT+
Sbjct: 40 IVGGIVNFISEAAAAQYTPEPPPTQQHFTSVEASESEEVRRFRQQFTQLAGPDMEVGATD 99
Query: 120 LMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYK 179
LMNILNKV+++H DLKTDGF +DTCRS+V+VMDSDTTGKLGFEEFKYLWNNIK+WQ +YK
Sbjct: 100 LMNILNKVLSKHKDLKTDGFSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIKKWQCVYK 159
Query: 180 QFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAM 239
Q+D D SG++ SS+L GA +AAGF LNE LY MI+RRY++E G+MDF+NFISCLVRLDAM
Sbjct: 160 QYDRDHSGSLGSSQLRGALQAAGFQLNEQLYQMIVRRYANEDGDMDFNNFISCLVRLDAM 219
Query: 240 FRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
FRAFKSLD+D G IQV+I+EWLQLTMYS
Sbjct: 220 FRAFKSLDRDRDGLIQVSIKEWLQLTMYS 248
>gi|47078247 calpain 3 isoform f [Homo sapiens]
Length = 728
Score = 224 bits (572), Expect = 5e-59
Identities = 106/192 (55%), Positives = 140/192 (72%), Gaps = 6/192 (3%)
Query: 77 NPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKT 136
+P+P P + ESEE +QFR +F Q+AGDDME+ A EL +LN VV +H DLKT
Sbjct: 543 SPQPQPGSSD------QESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKT 596
Query: 137 DGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPG 196
GF +++CRSM+A+MD+D +GKL +EF +LWN IK WQ I+K +DTD+SGTI S E+
Sbjct: 597 HGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRN 656
Query: 197 AFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQV 256
A AGFHLN LY++I RY+D+ N+DFD+FI C VRL+ MFRAF + DKDG G I++
Sbjct: 657 AVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 716
Query: 257 NIQEWLQLTMYS 268
N+ EWLQLTMY+
Sbjct: 717 NVLEWLQLTMYA 728
>gi|4557405 calpain 3 isoform a [Homo sapiens]
Length = 821
Score = 224 bits (572), Expect = 5e-59
Identities = 106/192 (55%), Positives = 140/192 (72%), Gaps = 6/192 (3%)
Query: 77 NPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKT 136
+P+P P + ESEE +QFR +F Q+AGDDME+ A EL +LN VV +H DLKT
Sbjct: 636 SPQPQPGSSD------QESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKT 689
Query: 137 DGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPG 196
GF +++CRSM+A+MD+D +GKL +EF +LWN IK WQ I+K +DTD+SGTI S E+
Sbjct: 690 HGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRN 749
Query: 197 AFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQV 256
A AGFHLN LY++I RY+D+ N+DFD+FI C VRL+ MFRAF + DKDG G I++
Sbjct: 750 AVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 809
Query: 257 NIQEWLQLTMYS 268
N+ EWLQLTMY+
Sbjct: 810 NVLEWLQLTMYA 821
>gi|27765072 calpain 3 isoform b [Homo sapiens]
Length = 815
Score = 224 bits (572), Expect = 5e-59
Identities = 106/192 (55%), Positives = 140/192 (72%), Gaps = 6/192 (3%)
Query: 77 NPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKT 136
+P+P P + ESEE +QFR +F Q+AGDDME+ A EL +LN VV +H DLKT
Sbjct: 630 SPQPQPGSSD------QESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKT 683
Query: 137 DGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPG 196
GF +++CRSM+A+MD+D +GKL +EF +LWN IK WQ I+K +DTD+SGTI S E+
Sbjct: 684 HGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRN 743
Query: 197 AFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQV 256
A AGFHLN LY++I RY+D+ N+DFD+FI C VRL+ MFRAF + DKDG G I++
Sbjct: 744 AVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 803
Query: 257 NIQEWLQLTMYS 268
N+ EWLQLTMY+
Sbjct: 804 NVLEWLQLTMYA 815
>gi|27765076 calpain 3 isoform d [Homo sapiens]
Length = 309
Score = 224 bits (572), Expect = 5e-59
Identities = 106/192 (55%), Positives = 140/192 (72%), Gaps = 6/192 (3%)
Query: 77 NPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKT 136
+P+P P + ESEE +QFR +F Q+AGDDME+ A EL +LN VV +H DLKT
Sbjct: 124 SPQPQPGSSD------QESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKT 177
Query: 137 DGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPG 196
GF +++CRSM+A+MD+D +GKL +EF +LWN IK WQ I+K +DTD+SGTI S E+
Sbjct: 178 HGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRN 237
Query: 197 AFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQV 256
A AGFHLN LY++I RY+D+ N+DFD+FI C VRL+ MFRAF + DKDG G I++
Sbjct: 238 AVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 297
Query: 257 NIQEWLQLTMYS 268
N+ EWLQLTMY+
Sbjct: 298 NVLEWLQLTMYA 309
>gi|27765074 calpain 3 isoform c [Homo sapiens]
Length = 729
Score = 223 bits (569), Expect = 1e-58
Identities = 103/175 (58%), Positives = 134/175 (76%)
Query: 94 ESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDS 153
ESEE +QFR +F Q+AGDDME+ A EL +LN VV +H DLKT GF +++CRSM+A+MD+
Sbjct: 555 ESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDT 614
Query: 154 DTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMI 213
D +GKL +EF +LWN IK WQ I+K +DTD+SGTI S E+ A AGFHLN LY++I
Sbjct: 615 DGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDII 674
Query: 214 IRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
RY+D+ N+DFD+FI C VRL+ MFRAF + DKDG G I++N+ EWLQLTMY+
Sbjct: 675 TMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 729
>gi|27765080 calpain 3 isoform e [Homo sapiens]
Length = 156
Score = 196 bits (499), Expect = 1e-50
Identities = 90/156 (57%), Positives = 118/156 (75%)
Query: 113 MEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIK 172
ME+ A EL +LN VV +H DLKT GF +++CRSM+A+MD+D +GKL +EF +LWN IK
Sbjct: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
Query: 173 RWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISC 232
WQ I+K +DTD+SGTI S E+ A AGFHLN LY++I RY+D+ N+DFD+FI C
Sbjct: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
Query: 233 LVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
VRL+ MFRAF + DKDG G I++N+ EWLQLTMY+
Sbjct: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
>gi|27765078 calpain 3 isoform e [Homo sapiens]
Length = 156
Score = 196 bits (499), Expect = 1e-50
Identities = 90/156 (57%), Positives = 118/156 (75%)
Query: 113 MEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIK 172
ME+ A EL +LN VV +H DLKT GF +++CRSM+A+MD+D +GKL +EF +LWN IK
Sbjct: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
Query: 173 RWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISC 232
WQ I+K +DTD+SGTI S E+ A AGFHLN LY++I RY+D+ N+DFD+FI C
Sbjct: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
Query: 233 LVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
VRL+ MFRAF + DKDG G I++N+ EWLQLTMY+
Sbjct: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
>gi|12408656 calpain 1, large subunit [Homo sapiens]
Length = 714
Score = 190 bits (482), Expect = 1e-48
Identities = 88/176 (50%), Positives = 127/176 (72%)
Query: 93 NESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMD 152
+E E F+ LF QLAG+DME+S EL ILN+++++H DL+T GF +++CRSMV +MD
Sbjct: 539 SEEEIDENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMD 598
Query: 153 SDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNM 212
D GKLG EF LWN I+ + +I+++FD D+SG++ + E+ A E+AGF LN+ LY +
Sbjct: 599 RDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYEL 658
Query: 213 IIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
II RYS+ +DFDNF+ CLVRL+ MFR FK+LD D G + ++ +WLQLTM++
Sbjct: 659 IITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA 714
>gi|157389005 calpain 2 isoform 1 [Homo sapiens]
Length = 700
Score = 180 bits (457), Expect = 1e-45
Identities = 87/197 (44%), Positives = 128/197 (64%)
Query: 66 ISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILN 125
I SE A Y + + +E + FRRLFAQLAG+D E+SA EL IL
Sbjct: 499 IRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILR 558
Query: 126 KVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDR 185
+V+ + D+K+DGF I+TC+ MV ++DSD +GKLG +EF LW I+++Q IY++ D DR
Sbjct: 559 RVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDR 618
Query: 186 SGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKS 245
SGT+ S E+ A E AGF + L+ +I+ R++D+ +DFDNF+ CLVRL+ +F+ FK
Sbjct: 619 SGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQ 678
Query: 246 LDKDGTGQIQVNIQEWL 262
LD + TG I++++ WL
Sbjct: 679 LDPENTGTIELDLISWL 695
>gi|225703100 calpain 2 isoform 2 [Homo sapiens]
Length = 622
Score = 180 bits (457), Expect = 1e-45
Identities = 87/197 (44%), Positives = 128/197 (64%)
Query: 66 ISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILN 125
I SE A Y + + +E + FRRLFAQLAG+D E+SA EL IL
Sbjct: 421 IRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILR 480
Query: 126 KVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDR 185
+V+ + D+K+DGF I+TC+ MV ++DSD +GKLG +EF LW I+++Q IY++ D DR
Sbjct: 481 RVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDR 540
Query: 186 SGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKS 245
SGT+ S E+ A E AGF + L+ +I+ R++D+ +DFDNF+ CLVRL+ +F+ FK
Sbjct: 541 SGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQ 600
Query: 246 LDKDGTGQIQVNIQEWL 262
LD + TG I++++ WL
Sbjct: 601 LDPENTGTIELDLISWL 617
>gi|7705383 calpain 9 isoform 2 [Homo sapiens]
Length = 664
Score = 165 bits (417), Expect = 4e-41
Identities = 80/189 (42%), Positives = 124/189 (65%), Gaps = 5/189 (2%)
Query: 78 PEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTD 137
PEPP P E+EE ++FR LF Q+AG+DMEV+A EL +LN V+ + D+K
Sbjct: 479 PEPPKPTP-----PDQETEEEQRFRALFEQVAGEDMEVTAEELEYVLNAVLQKKKDIKFK 533
Query: 138 GFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGA 197
+ +C++++++MD+ GKL F+EFK W+ +K+W ++ +FD D+SGT+ + EL A
Sbjct: 534 KLSLISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQWINLFLRFDADKSGTMSTYELRTA 593
Query: 198 FEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVN 257
+AAGF L+ HL +I+ RY+DE +DFD+F++CLVRL+ R F++L I +N
Sbjct: 594 LKAAGFQLSSHLLQLIVLRYADEELQLDFDDFLNCLVRLENASRVFQALSTKNKEFIHLN 653
Query: 258 IQEWLQLTM 266
I E++ LTM
Sbjct: 654 INEFIHLTM 662
>gi|5729758 calpain 9 isoform 1 [Homo sapiens]
Length = 690
Score = 165 bits (417), Expect = 4e-41
Identities = 80/189 (42%), Positives = 124/189 (65%), Gaps = 5/189 (2%)
Query: 78 PEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTD 137
PEPP P E+EE ++FR LF Q+AG+DMEV+A EL +LN V+ + D+K
Sbjct: 505 PEPPKPTP-----PDQETEEEQRFRALFEQVAGEDMEVTAEELEYVLNAVLQKKKDIKFK 559
Query: 138 GFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGA 197
+ +C++++++MD+ GKL F+EFK W+ +K+W ++ +FD D+SGT+ + EL A
Sbjct: 560 KLSLISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQWINLFLRFDADKSGTMSTYELRTA 619
Query: 198 FEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVN 257
+AAGF L+ HL +I+ RY+DE +DFD+F++CLVRL+ R F++L I +N
Sbjct: 620 LKAAGFQLSSHLLQLIVLRYADEELQLDFDDFLNCLVRLENASRVFQALSTKNKEFIHLN 679
Query: 258 IQEWLQLTM 266
I E++ LTM
Sbjct: 680 INEFIHLTM 688
>gi|215490104 calpain 11 [Homo sapiens]
Length = 739
Score = 156 bits (395), Expect = 2e-38
Identities = 71/177 (40%), Positives = 111/177 (62%)
Query: 91 EANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAV 150
+ +E + + F LF +AG+ E+ EL +LN++ + KT GFG+D CR M+ +
Sbjct: 562 KVSEDDMDQDFLHLFKIVAGEGKEIGVYELQRLLNRMAIKFKSFKTKGFGLDACRCMINL 621
Query: 151 MDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLY 210
MD D +GKLG EFK LW +K+W I+++ D D SGT+ S E+ E AG LN +
Sbjct: 622 MDKDGSGKLGLLEFKILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVIEKAGIKLNNKVM 681
Query: 211 NMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMY 267
+++ RY+D+ +DFD+FISC +RL MF F ++D TG I +++++WLQ+TM+
Sbjct: 682 QVLVARYADDDLIIDFDSFISCFLRLKTMFTFFLTMDPKNTGHICLSLEQWLQMTMW 738
>gi|221554549 calpain 8 [Homo sapiens]
Length = 703
Score = 150 bits (380), Expect = 9e-37
Identities = 74/181 (40%), Positives = 115/181 (63%), Gaps = 4/181 (2%)
Query: 82 PPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGI 141
P H S ++ +E QFRRLF +LAG D E++A L +LN+ ++ D+K DGF I
Sbjct: 522 PYEPHPSEVD----QEDDQFRRLFEKLAGKDSEITANALKILLNEAFSKRTDIKFDGFNI 577
Query: 142 DTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAA 201
+TCR M++++DS+ TG LG EFK LW I+++ IY + D + SGTI + E+ A A
Sbjct: 578 NTCREMISLLDSNGTGTLGAVEFKTLWLKIQKYLEIYWETDYNHSGTIDAHEMRTALRKA 637
Query: 202 GFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEW 261
GF LN + I RY+ ++FD+F++C++RL+ +F+ F LD+D G +Q+++ EW
Sbjct: 638 GFTLNSQVQQTIALRYACSKLGINFDSFVACMIRLETLFKLFSLLDEDKDGMVQLSLAEW 697
Query: 262 L 262
L
Sbjct: 698 L 698
>gi|4507207 sorcin isoform a [Homo sapiens]
Length = 198
Score = 106 bits (264), Expect = 2e-23
Identities = 72/230 (31%), Positives = 104/230 (45%), Gaps = 38/230 (16%)
Query: 37 GGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESE 96
G G GGG GG GG GG A + + P Y
Sbjct: 5 GHPGAGGGYYPGGYGGAPGGPA-----------------FPGQTQDPLYGY--------- 38
Query: 97 EVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTT 156
FA +AG D ++ A EL L + F ++TCR MV+++D D +
Sbjct: 39 --------FAAVAGQDGQIDADELQRCLTQSGIAGG---YKPFNLETCRLMVSMLDRDMS 87
Query: 157 GKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRR 216
G +GF EFK LW + W+ + FDTDRSGT+ EL A GF L+ N I +R
Sbjct: 88 GTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKR 147
Query: 217 YSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 266
YS +G + FD++I+C V+L A+ +F+ D G + +++Q M
Sbjct: 148 YS-TNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196
>gi|38679884 sorcin isoform b [Homo sapiens]
Length = 183
Score = 105 bits (262), Expect = 4e-23
Identities = 58/162 (35%), Positives = 88/162 (54%), Gaps = 4/162 (2%)
Query: 105 FAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEF 164
FA +AG D ++ A EL L + F ++TCR MV+++D D +G +GF EF
Sbjct: 24 FAAVAGQDGQIDADELQRCLTQSGIAGG---YKPFNLETCRLMVSMLDRDMSGTMGFNEF 80
Query: 165 KYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNM 224
K LW + W+ + FDTDRSGT+ EL A GF L+ N I +RYS +G +
Sbjct: 81 KELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYS-TNGKI 139
Query: 225 DFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 266
FD++I+C V+L A+ +F+ D G + +++Q M
Sbjct: 140 TFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 181
>gi|41152101 calpain 13 [Homo sapiens]
Length = 669
Score = 102 bits (253), Expect = 5e-22
Identities = 60/189 (31%), Positives = 106/189 (56%), Gaps = 10/189 (5%)
Query: 85 THYS-NIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDT 143
+H++ ++ + SE Q + +F + A +++ AT+L +LN+ + P D F +D
Sbjct: 486 SHFNLRMKGSPSEHGSQ-QSIFNRYAQQRLDIDATQLQGLLNQELLTGPP--GDMFSLDE 542
Query: 144 CRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAA-- 201
CRS+VA+M+ G+L EEF LW + +Q ++++ T G + SS+L A E
Sbjct: 543 CRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTS-PGVLLSSDLWKAIENTDF 601
Query: 202 --GFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQ 259
G ++ L +++ RYSD G + F + + L+RL+AM + F++L KDG G + +
Sbjct: 602 LRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKG-LYLTEM 660
Query: 260 EWLQLTMYS 268
EW+ L MY+
Sbjct: 661 EWMSLVMYN 669
>gi|6912388 grancalcin, EF-hand calcium binding protein [Homo
sapiens]
Length = 217
Score = 97.8 bits (242), Expect = 9e-21
Identities = 59/180 (32%), Positives = 93/180 (51%), Gaps = 7/180 (3%)
Query: 87 YSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRS 146
YS+ ++ + V + F+ +AG D EV A EL L + F ++TCR
Sbjct: 43 YSDTYSSAGDSVYTY---FSAVAGQDGEVDAEELQRCLTQSGINGT---YSPFSLETCRI 96
Query: 147 MVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLN 206
M+A++D D TGK+GF FK LW + W+ + D D SGT+ EL A G+ L+
Sbjct: 97 MIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLS 156
Query: 207 EHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 266
I++RYS ++G + FD++++C V+L A+ F+ D G ++LQ TM
Sbjct: 157 PQTLTTIVKRYS-KNGRIFFDDYVACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTM 215
>gi|38707981 calpain 12 [Homo sapiens]
Length = 719
Score = 96.3 bits (238), Expect = 3e-20
Identities = 54/168 (32%), Positives = 87/168 (51%), Gaps = 4/168 (2%)
Query: 103 RLFAQLAGDDMEVSATELMNILNKVV--TRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLG 160
+LF +LAG++ E++A++L +L+ + R G+ TC ++ + L
Sbjct: 554 QLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQLLQCFGHGQS--LA 611
Query: 161 FEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDE 220
F+ LW + WQAI+ +FD D SGT+ S EL A AAGFHLN L + RY D
Sbjct: 612 LHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQLTQTLTSRYRDS 671
Query: 221 SGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
+DF+ F+SC+ L +F G G I + ++W+++ +S
Sbjct: 672 RLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS 719
>gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
Length = 284
Score = 87.8 bits (216), Expect = 9e-18
Identities = 71/258 (27%), Positives = 110/258 (42%), Gaps = 26/258 (10%)
Query: 13 GGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEA 72
GGG GG GG G GG G G G G GG GG A G S
Sbjct: 43 GGGYGGPAPGGPYGPPAGG---GPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYG 99
Query: 73 AAQ---YNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVT 129
A Q Y PP + E F+ + + +G +S EL L
Sbjct: 100 AQQPGLYGQGGAPPNV--------DPEAYSWFQSVDSDHSG---YISMKELKQAL----- 143
Query: 130 RHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTI 189
+ F +TC M+ + D +G++ F LW I++W+ +++Q+D DRSG+I
Sbjct: 144 --VNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSI 201
Query: 190 CSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGN--MDFDNFISCLVRLDAMFRAFKSLD 247
+EL A G++L+ +++ RY S N M D FI +L + AF+ D
Sbjct: 202 SYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKD 261
Query: 248 KDGTGQIQVNIQEWLQLT 265
G I+++ ++++ +T
Sbjct: 262 TAVQGNIRLSFEDFVTMT 279
>gi|223468608 calpain 14 [Homo sapiens]
Length = 684
Score = 85.1 bits (209), Expect = 6e-17
Identities = 44/155 (28%), Positives = 87/155 (56%), Gaps = 2/155 (1%)
Query: 114 EVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKR 173
E++A +L N+LN++ + F ++ C+ ++A++D + +G + +EF+ LW +K
Sbjct: 532 EINAVQLQNLLNQMTWSSLGSRQPFFSLEACQGILALLDLNASGTMSIQEFRDLWKQLKL 591
Query: 174 WQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCL 233
Q ++ + D SG + +L A AG L++ + +++ RY MDF +FI +
Sbjct: 592 SQKVFHKQDRG-SGYLNWEQLHAAMREAGIMLSDDVCQLMLIRYGGPRLQMDFVSFIHLM 650
Query: 234 VRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
+R++ M F++L +DG G I + EW+ + +YS
Sbjct: 651 LRVENMEDVFQNLTQDGKG-IYLQKPEWMMMALYS 684
>gi|7019485 programmed cell death 6 [Homo sapiens]
Length = 191
Score = 79.0 bits (193), Expect = 4e-15
Identities = 37/123 (30%), Positives = 69/123 (56%), Gaps = 1/123 (0%)
Query: 143 TCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAG 202
T RS++++ D + + F EF +W I WQ +++ +D D SG I +EL A G
Sbjct: 64 TVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFG 123
Query: 203 FHLNEHLYNMIIRRYSDES-GNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEW 261
+ L++ ++++IR++ + G + FD+FI + L + F+ D D G IQV+ +++
Sbjct: 124 YRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQY 183
Query: 262 LQL 264
L +
Sbjct: 184 LSM 186
Score = 33.1 bits (74), Expect = 0.26
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 166 YLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGF-HLNEHLYNMIIRRYSDES-GN 223
+LWN ++++ D DRSG I +EL A + N II + E+
Sbjct: 27 FLWN-------VFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAG 79
Query: 224 MDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVN 257
++F F + F++ D+D +G I N
Sbjct: 80 VNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKN 113
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 73.2 bits (178), Expect = 2e-13
Identities = 34/48 (70%), Positives = 35/48 (72%)
Query: 9 KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
+GG GGGGGGGG GGG G G G GGG GGGGGGGGG GGGGGG
Sbjct: 335 RGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGG 382
Score = 72.8 bits (177), Expect = 3e-13
Identities = 35/47 (74%), Positives = 35/47 (74%), Gaps = 2/47 (4%)
Query: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
GGGGGGGG GG GGG G GG G GG GGGGGGGGG GGGGGGG
Sbjct: 339 GGGGGGGGRGGGGGGGGR--GGWGGGGGGWGGGGGGGGGWGGGGGGG 383
Score = 71.2 bits (173), Expect = 9e-13
Identities = 35/47 (74%), Positives = 35/47 (74%), Gaps = 1/47 (2%)
Query: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
GGGGGG GGGG GGG G GG G GGGGGGGGG GGGGGGG GG
Sbjct: 341 GGGGGGRGGGGGGGGRGG-WGGGGGGWGGGGGGGGGWGGGGGGGRGG 386
Score = 68.6 bits (166), Expect = 6e-12
Identities = 33/47 (70%), Positives = 33/47 (70%)
Query: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
GGG GG GGGG GGG G GG G GGGGGG GGGGGGGGG GG
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGG 378
Score = 61.6 bits (148), Expect = 7e-10
Identities = 36/69 (52%), Positives = 36/69 (52%), Gaps = 22/69 (31%)
Query: 10 GGGGGGGGGGGLGGGLGNVLG---------GLISGAGGGGG-------------GGGGGG 47
GGGGG GGGGG GGG G G G G GG GG GGGGGG
Sbjct: 361 GGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGG 420
Query: 48 GGGGGGGGG 56
GGGGGGGGG
Sbjct: 421 GGGGGGGGG 429
Score = 60.8 bits (146), Expect = 1e-09
Identities = 32/52 (61%), Positives = 33/52 (63%), Gaps = 14/52 (26%)
Query: 9 KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGG----GGGGGGGGGGGG 56
+GGGG GG GGG GGG G GGGGGGGG GGGGGG GGGGG
Sbjct: 330 EGGGGRGGWGGGGGGG----------GRGGGGGGGGRGGWGGGGGGWGGGGG 371
Score = 59.3 bits (142), Expect = 3e-09
Identities = 38/83 (45%), Positives = 38/83 (45%), Gaps = 34/83 (40%)
Query: 10 GGGGG----GGGGGGLGGGLGNVLGGLISGAGGGGGGG---------------------- 43
GGGGG GGGGGG GGG G GG G GGGG GG
Sbjct: 351 GGGGGRGGWGGGGGGWGGGGGG--GGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGR 408
Query: 44 ------GGGGGGGGGGGGGTAMR 60
GGGGGGGGGGGGG R
Sbjct: 409 GYGDPYGGGGGGGGGGGGGGGYR 431
Score = 44.3 bits (103), Expect = 1e-04
Identities = 20/30 (66%), Positives = 20/30 (66%)
Query: 35 GAGGGGGGGGGGGGGGGGGGGGTAMRILGG 64
G G GG GGGGGGGG GGGGGG GG
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGG 361
Score = 30.0 bits (66), Expect = 2.2
Identities = 14/21 (66%), Positives = 14/21 (66%)
Query: 44 GGGGGGGGGGGGGTAMRILGG 64
GGGG GG GGGGG R GG
Sbjct: 331 GGGGRGGWGGGGGGGGRGGGG 351
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 67.4 bits (163), Expect = 1e-11
Identities = 38/97 (39%), Positives = 48/97 (49%)
Query: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAI 69
GGG GGGG GG G G G + GG G G GGGG GGGG GGGG GGG G I +
Sbjct: 96 GGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEV 155
Query: 70 SEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFA 106
+ + P +++ E E+++ FA
Sbjct: 156 TINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFA 192
Score = 61.2 bits (147), Expect = 9e-10
Identities = 31/56 (55%), Positives = 36/56 (64%), Gaps = 3/56 (5%)
Query: 5 NSFLKGGG--GGGGGGGGLGG-GLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGT 57
+S+ GGG G GGGGGG G G G+ GG G+GGGGGG GG G GGG GG+
Sbjct: 557 SSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGS 612
Score = 60.8 bits (146), Expect = 1e-09
Identities = 31/47 (65%), Positives = 31/47 (65%)
Query: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
GGG GGGG GG G G G GG I G G GG G GGGG GGGG GGG
Sbjct: 91 GGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGG 137
Score = 58.9 bits (141), Expect = 4e-09
Identities = 37/77 (48%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
Query: 6 SFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGV 65
S +GGG G G GGG GGG G GG G GGGG GGGG GG G GGGG GG
Sbjct: 79 SVARGGGRGSGFGGGYGGG-GFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGG- 136
Query: 66 ISAISEAAAQYNPEPPP 82
Y P PP
Sbjct: 137 ----GGYGGGYGPVCPP 149
Score = 58.9 bits (141), Expect = 4e-09
Identities = 30/56 (53%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 10 GGGGGGGGGGGLGGGLGNVLGGLISGA-GGGGGGGGGGGGGGGGGGGGTAMRILGG 64
G GGG G GG GGG G+ G SG GG GGGGGG GG G GGG++ +GG
Sbjct: 560 GSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGG 615
Score = 57.0 bits (136), Expect = 2e-08
Identities = 32/63 (50%), Positives = 34/63 (53%), Gaps = 14/63 (22%)
Query: 8 LKGGGGGGGGGGGLG-GGLGNVLGGLISGAGGGGGGG-------------GGGGGGGGGG 53
+ GGG GGGGGG G GG GG G+GGGGGGG GGG G GGG
Sbjct: 512 ISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGG 571
Query: 54 GGG 56
GGG
Sbjct: 572 GGG 574
Score = 55.8 bits (133), Expect = 4e-08
Identities = 32/72 (44%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 6 SFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGG-GTAMRILGG 64
S+ GGGGGG G G G G GG SG GGGG GG G GGG GG G GG
Sbjct: 565 SYGSGGGGGGHGSYGSGSSSGGYRGG--SGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622
Query: 65 VISAISEAAAQY 76
V S+ ++ ++
Sbjct: 623 VKSSGGSSSVKF 634
Score = 55.5 bits (132), Expect = 5e-08
Identities = 35/78 (44%), Positives = 40/78 (51%), Gaps = 19/78 (24%)
Query: 5 NSFLKGGGGGGGGGGGLGGGLGNV-LGGLISGAGGGGGGGGGGGGG-------------- 49
+S+ GGG G GGGG GGG G+ GG G+GGG G GGGGGG
Sbjct: 530 SSYGSGGGSYGSGGGG-GGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYR 588
Query: 50 ---GGGGGGGTAMRILGG 64
GGGGGG + R GG
Sbjct: 589 GGSGGGGGGSSGGRGSGG 606
Score = 54.7 bits (130), Expect = 8e-08
Identities = 31/67 (46%), Positives = 32/67 (47%), Gaps = 20/67 (29%)
Query: 10 GGGGGGGGGGGL--------------------GGGLGNVLGGLISGAGGGGGGGGGGGGG 49
GGGG G GGG GGG G+ GG G G GGGG GGGG G
Sbjct: 51 GGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFG 110
Query: 50 GGGGGGG 56
GGG GGG
Sbjct: 111 GGGIGGG 117
Score = 52.0 bits (123), Expect = 5e-07
Identities = 38/82 (46%), Positives = 39/82 (47%), Gaps = 27/82 (32%)
Query: 10 GGGGG-----GGGGG--GLGGGLGNVL-----------------GGLISGAGGGGGGG-- 43
GGGGG GGGGG G GGG G+ GG SG GGG GGG
Sbjct: 40 GGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGF 99
Query: 44 -GGGGGGGGGGGGGTAMRILGG 64
GGG GGGG GGGG GG
Sbjct: 100 GGGGFGGGGFGGGGIGGGGFGG 121
Score = 38.9 bits (89), Expect = 0.005
Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 4/78 (5%)
Query: 2 FLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGG----GGGGGGGGGGGGGGT 57
F S + GGG G G+ +GGGGG GGGGG G GGG G+
Sbjct: 5 FSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGS 64
Query: 58 AMRILGGVISAISEAAAQ 75
+ G +IS + A+
Sbjct: 65 RSLVNLGGSKSISISVAR 82
>gi|12056465 fibrillarin [Homo sapiens]
Length = 321
Score = 66.2 bits (160), Expect = 3e-11
Identities = 32/47 (68%), Positives = 32/47 (68%), Gaps = 2/47 (4%)
Query: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
G GG GG GG GGG G GG G G GGGGGGGGGGGGG GGGG
Sbjct: 19 GDRGGRGGRGGFGGGRGR--GGGFRGRGRGGGGGGGGGGGGGRGGGG 63
Score = 59.3 bits (142), Expect = 3e-09
Identities = 32/56 (57%), Positives = 33/56 (58%), Gaps = 3/56 (5%)
Query: 9 KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGG 64
+GG GG GGG G GGG G G GGGGGGGGGG GGGG GG R GG
Sbjct: 24 RGGRGGFGGGRGRGGGFRGRGRG---GGGGGGGGGGGGRGGGGFHSGGNRGRGRGG 76
Score = 58.5 bits (140), Expect = 6e-09
Identities = 32/52 (61%), Positives = 33/52 (63%), Gaps = 5/52 (9%)
Query: 9 KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGG----GGGGGGGGGGGGGGG 56
+GGG GG GG G GG G GG G G GGG G GGGGGGGGGGGGG
Sbjct: 8 RGGGFGGRGGFGDRGGRGG-RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGG 58
Score = 44.7 bits (104), Expect = 9e-05
Identities = 23/43 (53%), Positives = 24/43 (55%)
Query: 9 KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGG 51
+G G GGGGGGG GGG G GG SG G G GG G G
Sbjct: 41 RGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83
Score = 42.4 bits (98), Expect = 4e-04
Identities = 26/52 (50%), Positives = 27/52 (51%), Gaps = 12/52 (23%)
Query: 9 KGGG----GGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
+GGG G GGGGGG GGG G G GGGG GG G G GG G
Sbjct: 36 RGGGFRGRGRGGGGGGGGGGGG--------GRGGGGFHSGGNRGRGRGGKRG 79
>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
Length = 532
Score = 66.2 bits (160), Expect = 3e-11
Identities = 31/49 (63%), Positives = 32/49 (65%), Gaps = 9/49 (18%)
Query: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTA 58
GG G GG GGG GGG SG+GGGGGG GGGGGG GGG GTA
Sbjct: 478 GGSGSGGAGGGSGGG---------SGSGGGGGGAGGGGGGSSGGGSGTA 517
Score = 28.1 bits (61), Expect = 8.4
Identities = 13/25 (52%), Positives = 13/25 (52%)
Query: 10 GGGGGGGGGGGLGGGLGNVLGGLIS 34
G GGGGGG G G G GL S
Sbjct: 501 GAGGGGGGSSGGGSGTAGGHSGLSS 525
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 63.9 bits (154), Expect = 1e-10
Identities = 41/91 (45%), Positives = 46/91 (50%), Gaps = 26/91 (28%)
Query: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGG------------GGGGGGGGGGG---- 53
G GGGGGGGGG GGG G GG +GAGG G G GGGGGGG GG
Sbjct: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG 306
Query: 54 ----------GGGTAMRILGGVISAISEAAA 74
GGG M GG +++S+AAA
Sbjct: 307 YGVLSSPRQQGGGMMMGPGGGGAASLSKAAA 337
Score = 57.4 bits (137), Expect = 1e-08
Identities = 35/80 (43%), Positives = 40/80 (50%), Gaps = 28/80 (35%)
Query: 7 FLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGG----------------- 49
+ + G GGGGGGGG GGG G+GGGGGGGG G GG
Sbjct: 243 YSRPGAGGGGGGGGGGGG----------GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA 292
Query: 50 GGGGGGGTAMRILG-GVISA 68
GGGGGGG G GV+S+
Sbjct: 293 GGGGGGGYGGSSAGYGVLSS 312
Score = 40.8 bits (94), Expect = 0.001
Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 6/51 (11%)
Query: 11 GGGGGGGGGGLGGGLGNVL------GGLISGAGGGGGGGGGGGGGGGGGGG 55
GGGGGGG GG G G + GG++ G GGGG G GG
Sbjct: 293 GGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGG 343
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.140 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,019,029
Number of Sequences: 37866
Number of extensions: 722942
Number of successful extensions: 41881
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 753
Number of HSP's successfully gapped in prelim test: 175
Number of HSP's that attempted gapping in prelim test: 10669
Number of HSP's gapped (non-prelim): 10804
length of query: 268
length of database: 18,247,518
effective HSP length: 100
effective length of query: 168
effective length of database: 14,460,918
effective search space: 2429434224
effective search space used: 2429434224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.