Guide to the Human Genome
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Search of human proteins with 45007002

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45007002 longevity assurance homolog 6 [Homo sapiens]
         (384 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45007002 longevity assurance homolog 6 [Homo sapiens]              810   0.0  
gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens]          535   e-152
gi|32455256 LAG1 longevity assurance 2 [Homo sapiens]                 320   1e-87
gi|31077094 LAG1 longevity assurance 2 [Homo sapiens]                 320   1e-87
gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens]         319   2e-87
gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens]        298   4e-81
gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo sa...   100   2e-21
gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo sa...   100   2e-21
gi|7657655 translocation associated membrane protein 1 [Homo sap...    57   2e-08
gi|6912450 translocation-associated membrane protein 2 [Homo sap...    54   2e-07
gi|19743884 regulatory factor X3 isoform b [Homo sapiens]              32   1.3  
gi|224282187 HOP homeobox isoform a [Homo sapiens]                     31   2.1  
gi|224451023 HOP homeobox isoform b [Homo sapiens]                     31   2.1  
gi|21264589 HOP homeobox isoform b [Homo sapiens]                      31   2.1  
gi|21264587 HOP homeobox isoform b [Homo sapiens]                      31   2.1  
gi|24308434 glucose-6-phosphatase catalytic subunit 3 [Homo sapi...    31   2.1  
gi|14149865 family with sequence similarity 176, member A [Homo ...    30   4.8  
gi|205277349 family with sequence similarity 176, member A [Homo...    30   4.8  
gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens]             29   6.2  
gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]             29   6.2  
gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens]             29   6.2  
gi|30410785 LIM homeobox protein 1 [Homo sapiens]                      29   6.2  
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]            29   8.1  
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]             29   8.1  

>gi|45007002 longevity assurance homolog 6 [Homo sapiens]
          Length = 384

 Score =  810 bits (2091), Expect = 0.0
 Identities = 384/384 (100%), Positives = 384/384 (100%)

Query: 1   MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVA 60
           MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVA
Sbjct: 1   MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVA 60

Query: 61  KPCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQR 120
           KPCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQR
Sbjct: 61  KPCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQR 120

Query: 121 RNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHY 180
           RNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHY
Sbjct: 121 RNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHY 180

Query: 181 YYILELSFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDS 240
           YYILELSFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDS
Sbjct: 181 YYILELSFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDS 240

Query: 241 ADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPS 300
           ADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPS
Sbjct: 241 ADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPS 300

Query: 301 WWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGKNPH 360
           WWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGKNPH
Sbjct: 301 WWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGKNPH 360

Query: 361 TATTTNGTSGTNGYLLTGSCSMDD 384
           TATTTNGTSGTNGYLLTGSCSMDD
Sbjct: 361 TATTTNGTSGTNGYLLTGSCSMDD 384


>gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens]
          Length = 392

 Score =  535 bits (1377), Expect = e-152
 Identities = 241/370 (65%), Positives = 305/370 (82%), Gaps = 1/370 (0%)

Query: 7   WFWNERFWLPHNVTWADLKNTEEAT-FPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAI 65
           W W+ERFWLP NV+WADL+   +   +P+   +   FPLA  IF VRL+FERF+AKPCA+
Sbjct: 15  WLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFVRLLFERFIAKPCAL 74

Query: 66  ALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEK 125
            + I+ +GP  A PNAILEKVF +ITK+PD+KRLEGLSKQLDW+VR IQ WFR RRNQ+K
Sbjct: 75  CIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDK 134

Query: 126 PSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILE 185
           P TLT+FCESMWRF+FYL +F YG+RFL  +PW W+ R CW+NYP+QPL++ L++YYI+E
Sbjct: 135 PPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIME 194

Query: 186 LSFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALL 245
           L+FYWSLMFSQFTDIKRKDF IMF+HHLV+I LI+FSY+NNM RVGTL++CLHD +D LL
Sbjct: 195 LAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDFLL 254

Query: 246 EAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFN 305
           EAAK+ANYAK+Q++CD LFV+F+ VF+ TRLGI+P W+LNTTLFESWEI+GPY SWW+ N
Sbjct: 255 EAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFESWEIIGPYASWWLLN 314

Query: 306 LLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGKNPHTATTT 365
            LLL +Q L+  WSYLI +IA KA+ RGKVSKDDRSD+ESSS+EED     K+P  ++++
Sbjct: 315 GLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEEDVTTCTKSPCDSSSS 374

Query: 366 NGTSGTNGYL 375
           NG +  NG++
Sbjct: 375 NGANRVNGHM 384


>gi|32455256 LAG1 longevity assurance 2 [Homo sapiens]
          Length = 380

 Score =  320 bits (820), Expect = 1e-87
 Identities = 153/347 (44%), Positives = 225/347 (64%), Gaps = 1/347 (0%)

Query: 7   WFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIA 66
           +FW ER WLP N+TWADL++ +   + +A DLY+  PLA    +VR  FE +VA P A  
Sbjct: 8   YFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVATPLAAL 67

Query: 67  LNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKP 126
           LNI+      APPNA LE  +    K P +  +E LS+Q     R ++RWFR+RRNQ++P
Sbjct: 68  LNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRP 127

Query: 127 STLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILEL 186
           S L +F E+ WRF+FYL  F  G+  +   PW ++ +  W  YP Q      ++YY++EL
Sbjct: 128 SLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIEL 187

Query: 187 SFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLE 246
           SFYWSL+FS  +D+KRKDF    +HH+ +I LI+FS+  N  R GTL++ LHDS+D LLE
Sbjct: 188 SFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLE 247

Query: 247 AAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNL 306
           +AKM NYA ++  C+ +F++FA+VFI TRL I P W+L+ TL    E+   +  ++ FN 
Sbjct: 248 SAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFFGYYFFNS 307

Query: 307 LLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSE 353
           ++ ++Q L+ FW+YLI+++A K ++ GK+ +D+RSD E +   E  E
Sbjct: 308 MMGVLQLLHIFWAYLILRMAHKFIT-GKLVEDERSDREETESSEGEE 353


>gi|31077094 LAG1 longevity assurance 2 [Homo sapiens]
          Length = 380

 Score =  320 bits (820), Expect = 1e-87
 Identities = 153/347 (44%), Positives = 225/347 (64%), Gaps = 1/347 (0%)

Query: 7   WFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIA 66
           +FW ER WLP N+TWADL++ +   + +A DLY+  PLA    +VR  FE +VA P A  
Sbjct: 8   YFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVATPLAAL 67

Query: 67  LNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKP 126
           LNI+      APPNA LE  +    K P +  +E LS+Q     R ++RWFR+RRNQ++P
Sbjct: 68  LNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRP 127

Query: 127 STLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILEL 186
           S L +F E+ WRF+FYL  F  G+  +   PW ++ +  W  YP Q      ++YY++EL
Sbjct: 128 SLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIEL 187

Query: 187 SFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLE 246
           SFYWSL+FS  +D+KRKDF    +HH+ +I LI+FS+  N  R GTL++ LHDS+D LLE
Sbjct: 188 SFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLE 247

Query: 247 AAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNL 306
           +AKM NYA ++  C+ +F++FA+VFI TRL I P W+L+ TL    E+   +  ++ FN 
Sbjct: 248 SAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFFGYYFFNS 307

Query: 307 LLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSE 353
           ++ ++Q L+ FW+YLI+++A K ++ GK+ +D+RSD E +   E  E
Sbjct: 308 MMGVLQLLHIFWAYLILRMAHKFIT-GKLVEDERSDREETESSEGEE 353


>gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens]
          Length = 394

 Score =  319 bits (818), Expect = 2e-87
 Identities = 154/346 (44%), Positives = 218/346 (63%)

Query: 7   WFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIA 66
           WFW +RFWLP NVTW +L++ +   +P  +DL  A PLA  +  +RL FERF+  P +  
Sbjct: 8   WFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFIGLPLSRW 67

Query: 67  LNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKP 126
           L ++    +   PNA LEK F      P E +L  L+ Q    ++  QRWFR+RRNQ++P
Sbjct: 68  LGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRRRRNQDRP 127

Query: 127 STLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILEL 186
               +FCE+ WRF FYL  F  G+  L    WLW    CW  YP Q L   L+++Y+LEL
Sbjct: 128 QLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLYWWYLLEL 187

Query: 187 SFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLE 246
            FY SL+     D+KRKDF    +HH V++ L+TFSY  N+ R+G+LVL LHDS+D LLE
Sbjct: 188 GFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHDSSDYLLE 247

Query: 247 AAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNL 306
           A KM NY ++Q++CD LF++F+ VF  TRL +FP  +L TT +ES    GP+  ++ FN 
Sbjct: 248 ACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFFGYYFFNG 307

Query: 307 LLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDS 352
           LL+L+Q L+ FWS LI+++    + +G++ KD RSD+E S   E++
Sbjct: 308 LLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEA 353


>gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens]
          Length = 383

 Score =  298 bits (764), Expect = 4e-81
 Identities = 145/347 (41%), Positives = 216/347 (62%), Gaps = 2/347 (0%)

Query: 7   WFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIA 66
           WFW ERFWLP  + W+DL++ +   F +   LY+  P AF + ++R +FE+FVA P A +
Sbjct: 8   WFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFVASPLAKS 67

Query: 67  LNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKP 126
             I+    ++ P N +LE  F   T+ P +  + GL+K+ +   R ++RWFR RRNQE+P
Sbjct: 68  FGIKETVRKVTP-NTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQERP 126

Query: 127 STLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILEL 186
           S L +F E+ WRF+FYL +   G+ FL   PWL++    W  YP QPL    ++YYILE+
Sbjct: 127 SRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILEM 186

Query: 187 SFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLE 246
           SFYWSL+F    D+KRKDF    +HHL +I L++FS+  N  R GTLV+ +HD AD  LE
Sbjct: 187 SFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDVADIWLE 246

Query: 247 AAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNL 306
           +AKM +YA + + C+ LF +F+ +F  +RL +FP W+L  TL      + P+ S+   NL
Sbjct: 247 SAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFFSYIFLNL 306

Query: 307 LLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSE 353
            L+++Q L+ +W Y I+K+  + +   K  +D RSD E   +EE+ E
Sbjct: 307 QLMILQVLHLYWGYYILKMLNRCIFM-KSIQDVRSDDEDYEEEEEEE 352


>gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo
           sapiens]
          Length = 337

 Score =  100 bits (249), Expect = 2e-21
 Identities = 84/248 (33%), Positives = 119/248 (47%), Gaps = 19/248 (7%)

Query: 125 KPSTLTRFCESMWRFSFYLYVFTYGVRFLKKT--PWLWNTRHCWYNY-PYQPLTTDLHYY 181
           +P    +  ES W+F FYL  ++Y    L  T  P+  +    +Y++ P   +  D+   
Sbjct: 92  QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151

Query: 182 YILELSFYW-SLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDS 240
           Y+L+ SFY  S+  + + D  RKD  +M LHH+V++ LI  SY      VG LVL LHD 
Sbjct: 152 YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDI 211

Query: 241 ADALLEAAKMANYAKFQ---------KMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFES 291
           +D  LE  K+  Y K +            DL  + F   +   RL  FPL VL  T   S
Sbjct: 212 SDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCS 271

Query: 292 WEIVGPYPSWWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVS--KDDRSDIESSSDE 349
              V   P ++ FN LLLL+  +N +W   IV  A K ++ G+V   KD R   E  + E
Sbjct: 272 LRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLT-GQVHELKDLR---EYDTAE 327

Query: 350 EDSEPPGK 357
             S  P K
Sbjct: 328 AQSLKPSK 335


>gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo
           sapiens]
          Length = 350

 Score =  100 bits (249), Expect = 2e-21
 Identities = 84/248 (33%), Positives = 119/248 (47%), Gaps = 19/248 (7%)

Query: 125 KPSTLTRFCESMWRFSFYLYVFTYGVRFLKKT--PWLWNTRHCWYNY-PYQPLTTDLHYY 181
           +P    +  ES W+F FYL  ++Y    L  T  P+  +    +Y++ P   +  D+   
Sbjct: 92  QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151

Query: 182 YILELSFYW-SLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDS 240
           Y+L+ SFY  S+  + + D  RKD  +M LHH+V++ LI  SY      VG LVL LHD 
Sbjct: 152 YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDI 211

Query: 241 ADALLEAAKMANYAKFQ---------KMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFES 291
           +D  LE  K+  Y K +            DL  + F   +   RL  FPL VL  T   S
Sbjct: 212 SDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCS 271

Query: 292 WEIVGPYPSWWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVS--KDDRSDIESSSDE 349
              V   P ++ FN LLLL+  +N +W   IV  A K ++ G+V   KD R   E  + E
Sbjct: 272 LRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLT-GQVHELKDLR---EYDTAE 327

Query: 350 EDSEPPGK 357
             S  P K
Sbjct: 328 AQSLKPSK 335


>gi|7657655 translocation associated membrane protein 1 [Homo
           sapiens]
          Length = 374

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 44/169 (26%), Positives = 84/169 (49%), Gaps = 9/169 (5%)

Query: 120 RRNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLH 179
           RR     +  ++F ES    +FYL+   +G   L    ++ +    W  YP+  +T  + 
Sbjct: 107 RRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMK 166

Query: 180 YYYILELSFYWSLMFSQ--FTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCL 237
           ++YI +L+ YW   F +  F   K++D     ++  + +F I  +Y+ N+  +G ++L L
Sbjct: 167 FFYISQLA-YWLHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVL 225

Query: 238 HDSADALLEAAKMANYA--KFQKMCDLLFVMFAVVFITTRLGIFPLWVL 284
           H   + L   +++  ++  K+QK     F ++AV+F+  RL    L VL
Sbjct: 226 HYFVEFLFHISRLFYFSNEKYQKG----FSLWAVLFVLGRLLTLILSVL 270


>gi|6912450 translocation-associated membrane protein 2 [Homo
           sapiens]
          Length = 370

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 54/207 (26%), Positives = 97/207 (46%), Gaps = 23/207 (11%)

Query: 82  ILEKVFTAITKHP--DEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRF 139
           IL  +F  I  H    E  L+ +SK+L      + +    + N+     +  F   +W  
Sbjct: 78  ILFYIFITIILHAVVQEYILDKISKRLH-----LSKVKHSKFNESGQLVVFHFTSVIW-- 130

Query: 140 SFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILELSFYW--SLMFSQF 197
            FY+ V T G        +L N R  W +YP+  L   + ++Y+ +L+ YW  +L    F
Sbjct: 131 CFYVVV-TEG--------YLTNPRSLWEDYPHVHLPFQVKFFYLCQLA-YWLHALPELYF 180

Query: 198 TDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQ 257
             +++++      +  + +  I  +Y+ N++R+G ++L L  S + L   A++  +A   
Sbjct: 181 QKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFA--D 238

Query: 258 KMCDLLFVMFAVVFITTRLGIFPLWVL 284
           +  + LF  +A VF  TRL I  L VL
Sbjct: 239 ENNEKLFSAWAAVFGVTRLFILTLAVL 265


>gi|19743884 regulatory factor X3 isoform b [Homo sapiens]
          Length = 749

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 17/36 (47%), Positives = 21/36 (58%), Gaps = 3/36 (8%)

Query: 329 AVSRGKVSKDDRSDIESSSDEE---DSEPPGKNPHT 361
           AVS G + KD+ S++ES  DEE    SEP  K   T
Sbjct: 662 AVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKT 697


>gi|224282187 HOP homeobox isoform a [Homo sapiens]
          Length = 91

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 14/39 (35%), Positives = 20/39 (51%)

Query: 82  ILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQR 120
           ILE  F  + KHPD   L  ++ +        Q+WF+QR
Sbjct: 34  ILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKWFKQR 72


>gi|224451023 HOP homeobox isoform b [Homo sapiens]
          Length = 73

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 14/39 (35%), Positives = 20/39 (51%)

Query: 82  ILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQR 120
           ILE  F  + KHPD   L  ++ +        Q+WF+QR
Sbjct: 16  ILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKWFKQR 54


>gi|21264589 HOP homeobox isoform b [Homo sapiens]
          Length = 73

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 14/39 (35%), Positives = 20/39 (51%)

Query: 82  ILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQR 120
           ILE  F  + KHPD   L  ++ +        Q+WF+QR
Sbjct: 16  ILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKWFKQR 54


>gi|21264587 HOP homeobox isoform b [Homo sapiens]
          Length = 73

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 14/39 (35%), Positives = 20/39 (51%)

Query: 82  ILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQR 120
           ILE  F  + KHPD   L  ++ +        Q+WF+QR
Sbjct: 16  ILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKWFKQR 54


>gi|24308434 glucose-6-phosphatase catalytic subunit 3 [Homo
           sapiens]
          Length = 346

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 4/45 (8%)

Query: 263 LFVMFAVVFITTRLGIFPLWVLNTT----LFESWEIVGPYPSWWV 303
           LF   A  + + R+GI  LW+   T    L   W + G  P WWV
Sbjct: 40  LFYFPAAYYASRRVGIAVLWISLITEWLNLIFKWFLFGDRPFWWV 84


>gi|14149865 family with sequence similarity 176, member A [Homo
           sapiens]
          Length = 152

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 313 GLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSE 353
           GL    + L+++I+C    R +  K    D ESSSD  DSE
Sbjct: 45  GLVLTLAALVIRISCHTDCRRRPGKKFLQDRESSSDSSDSE 85


>gi|205277349 family with sequence similarity 176, member A [Homo
           sapiens]
          Length = 152

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 16/41 (39%), Positives = 22/41 (53%)

Query: 313 GLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSE 353
           GL    + L+++I+C    R +  K    D ESSSD  DSE
Sbjct: 45  GLVLTLAALVIRISCHTDCRRRPGKKFLQDRESSSDSSDSE 85


>gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens]
          Length = 1941

 Score = 29.3 bits (64), Expect = 6.2
 Identities = 16/62 (25%), Positives = 35/62 (56%), Gaps = 3/62 (4%)

Query: 298  YPSWWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGK 357
            Y   +V  L++ L  GL  F ++L+  +  + ++  + S+++  D+  +++EE+S  PG 
Sbjct: 983  YTDCFVAQLMVRL--GLQAFLTHLLPHVL-QVLAGAEASQEESKDLAGAAEEEESGLPGA 1039

Query: 358  NP 359
             P
Sbjct: 1040 GP 1041


>gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]
          Length = 2240

 Score = 29.3 bits (64), Expect = 6.2
 Identities = 16/62 (25%), Positives = 35/62 (56%), Gaps = 3/62 (4%)

Query: 298  YPSWWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGK 357
            Y   +V  L++ L  GL  F ++L+  +  + ++  + S+++  D+  +++EE+S  PG 
Sbjct: 1282 YTDCFVAQLMVRL--GLQAFLTHLLPHVL-QVLAGAEASQEESKDLAGAAEEEESGLPGA 1338

Query: 358  NP 359
             P
Sbjct: 1339 GP 1340


>gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens]
          Length = 1941

 Score = 29.3 bits (64), Expect = 6.2
 Identities = 16/62 (25%), Positives = 35/62 (56%), Gaps = 3/62 (4%)

Query: 298  YPSWWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGK 357
            Y   +V  L++ L  GL  F ++L+  +  + ++  + S+++  D+  +++EE+S  PG 
Sbjct: 983  YTDCFVAQLMVRL--GLQAFLTHLLPHVL-QVLAGAEASQEESKDLAGAAEEEESGLPGA 1039

Query: 358  NP 359
             P
Sbjct: 1040 GP 1041


>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
          Length = 406

 Score = 29.3 bits (64), Expect = 6.2
 Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 2/61 (3%)

Query: 67  LNIQANGPQIAPPNAILE--KVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQE 124
           L  +  GP+       LE  K   A T  P     E L+++   ++R IQ WF+ RR++E
Sbjct: 176 LGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKE 235

Query: 125 K 125
           +
Sbjct: 236 R 236


>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
          Length = 397

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 2/45 (4%)

Query: 83  LEKVFTAITKHPDEKR--LEGLSKQLDWDVRSIQRWFRQRRNQEK 125
           LE + +A    P   R   E LS +   D+R +Q WF+ RR +EK
Sbjct: 169 LETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEK 213


>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
          Length = 402

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 2/45 (4%)

Query: 83  LEKVFTAITKHPDEKR--LEGLSKQLDWDVRSIQRWFRQRRNQEK 125
           LE + +A    P   R   E LS +   D+R +Q WF+ RR +EK
Sbjct: 174 LETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEK 218


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.462 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,950,288
Number of Sequences: 37866
Number of extensions: 617804
Number of successful extensions: 2750
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2723
Number of HSP's gapped (non-prelim): 26
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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