Search of human proteins with 44888818

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|44888818 DIP2 disco-interacting protein 2 homolog C [Homo
sapiens]
         (1556 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|44888818 DIP2 disco-interacting protein 2 homolog C [Homo sap...  3136   0.0  
gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]    2398   0.0  
gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]   2384   0.0  
gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo sap...  2347   0.0  
gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens]   1593   0.0  
gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens]    1198   0.0  
gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens]    1130   0.0  
gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]   1079   0.0  
gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens]    1060   0.0  
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         39   0.039
gi|164663780 zinc finger protein 385B isoform 3 [Homo sapiens]         38   0.067
gi|164663778 zinc finger protein 385B isoform 2 [Homo sapiens]         38   0.067
gi|63029928 zinc finger protein 385B isoform 1 [Homo sapiens]          38   0.067
gi|186928825 dermokine isoform 3 precursor [Homo sapiens]              38   0.067
gi|161016767 mucin 21 [Homo sapiens]                                   37   0.15 
gi|5174653 ring finger protein 6 [Homo sapiens]                        36   0.33 
gi|161019170 mucin 5AC [Homo sapiens]                                  36   0.33 
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              36   0.33 
gi|34305295 ring finger protein 6 [Homo sapiens]                       36   0.33 
gi|34305293 ring finger protein 6 [Homo sapiens]                       36   0.33 
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]    36   0.33 
gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo ...    35   0.43 
gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo ...    35   0.43 
gi|167234419 thyroid hormone receptor associated protein 3 [Homo...    35   0.43 
gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens]       35   0.57 
gi|38202211 N-acetylglucosamine-1-phosphate transferase [Homo sa...    35   0.57 
gi|63055059 SH3 and PX domains 2B [Homo sapiens]                       35   0.74 
gi|55741677 SET domain containing 1A [Homo sapiens]                    34   0.96 
gi|27477105 lipidosin [Homo sapiens]                                   34   0.96 
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    34   0.96 

>gi|44888818 DIP2 disco-interacting protein 2 homolog C [Homo sapiens]
          Length = 1556

 Score = 3136 bits (8131), Expect = 0.0
 Identities = 1556/1556 (100%), Positives = 1556/1556 (100%)

Query: 1    MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQALPQ 60
            MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQALPQ
Sbjct: 1    MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQALPQ 60

Query: 61   ERRAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLV 120
            ERRAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLV
Sbjct: 61   ERRAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLV 120

Query: 121  VQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSS 180
            VQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSS
Sbjct: 121  VQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSS 180

Query: 181  TQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAE 240
            TQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAE
Sbjct: 181  TQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAE 240

Query: 241  LMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGA 300
            LMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGA
Sbjct: 241  LMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGA 300

Query: 301  QMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSM 360
            QMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSM
Sbjct: 301  QMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSM 360

Query: 361  KVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRK 420
            KVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRK
Sbjct: 361  KVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRK 420

Query: 421  DAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPP 480
            DAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPP
Sbjct: 421  DAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPP 480

Query: 481  RDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVL 540
            RDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVL
Sbjct: 481  RDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVL 540

Query: 541  DFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWAL 600
            DFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWAL
Sbjct: 541  DFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWAL 600

Query: 601  VAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTV 660
            VAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTV
Sbjct: 601  VAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTV 660

Query: 661  AIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDG 720
            AIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDG
Sbjct: 661  AIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDG 720

Query: 721  VPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGF 780
            VPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGF
Sbjct: 721  VPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGF 780

Query: 781  VGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERI 840
            VGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERI
Sbjct: 781  VGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERI 840

Query: 841  VIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQ 900
            VIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQ
Sbjct: 841  VIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQ 900

Query: 901  LFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQI 960
            LFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQI
Sbjct: 901  LFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQI 960

Query: 961  EDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLME 1020
            EDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLME
Sbjct: 961  EDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLME 1020

Query: 1021 RGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSR 1080
            RGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSR
Sbjct: 1021 RGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSR 1080

Query: 1081 SACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFS 1140
            SACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFS
Sbjct: 1081 SACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFS 1140

Query: 1141 VSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGH 1200
            VSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGH
Sbjct: 1141 VSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGH 1200

Query: 1201 QSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRV 1260
            QSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRV
Sbjct: 1201 QSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRV 1260

Query: 1261 RTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTTVYV 1320
            RTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTTVYV
Sbjct: 1261 RTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTTVYV 1320

Query: 1321 DMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAH 1380
            DMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAH
Sbjct: 1321 DMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAH 1380

Query: 1381 NASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVV 1440
            NASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVV
Sbjct: 1381 NASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVV 1440

Query: 1441 GALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDLVP 1500
            GALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDLVP
Sbjct: 1441 GALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDLVP 1500

Query: 1501 LVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM 1556
            LVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
Sbjct: 1501 LVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM 1556


>gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]
          Length = 1571

 Score = 2398 bits (6214), Expect = 0.0
 Identities = 1171/1575 (74%), Positives = 1351/1575 (85%), Gaps = 23/1575 (1%)

Query: 1    MADRS--LEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQAL 58
            MADR   LE   LP EVR  LAELELELSEGDITQKGYEKKR+KL+  Y+P    +D +L
Sbjct: 1    MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 59   PQERRAP---VTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSK 115
              E R P    T ++A +  + R + SRDER+RSDVHTEAVQAALAK+KERKM  PMPSK
Sbjct: 61   QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM--PMPSK 118

Query: 116  RRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTS- 174
            RRS++V +S++ YTPPDTSS SEDEGS++   + T T  Q   ++E W+ + I GS+TS 
Sbjct: 119  RRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSS 178

Query: 175  -------------TTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQV 221
                         TT+ S+  + G+ A   LA + A THI+ HSAPPDVTT   EHS   
Sbjct: 179  SASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSY-F 237

Query: 222  ERPQGSTGSRTAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDF 281
            ERPQ ++  R+ P+  +  ++ET DGVPV+SRVS+KIQQL+NTLKRPKRPPL+EFFVDDF
Sbjct: 238  ERPQVAS-VRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDF 296

Query: 282  EELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMD 341
            EELLEVQQPDPNQPKPEG++   +RGE L      PPSL A LQRWGT  PK+PCLT +D
Sbjct: 297  EELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALD 356

Query: 342  TNGKPLYILTYGKLWTRSMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFY 401
            T GK +Y LTYGKLW+RS+K+AY++L+KL +K EP+++PGDRVALVFPN+DP  FM AFY
Sbjct: 357  TTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFY 416

Query: 402  GCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFK 461
            GCLLAE+VPVPIEVPLTRKDAGSQQ+GFLLGSCGV +ALT+DAC KGLPK+ TGE+  FK
Sbjct: 417  GCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFK 476

Query: 462  GWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHC 521
            GWP L W V + KHL+KPP+DW P  +D    TAYIEYKT K+GS +GVTV+  +LL  C
Sbjct: 477  GWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQC 536

Query: 522  QALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKV 581
            +ALTQACGY+EAET+ NVLDFK+D GLWHG+LTSVMN MHV+S+PY+LMK NPLSWIQKV
Sbjct: 537  RALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKV 596

Query: 582  CQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSK 641
            C YKA+ A VKSRDMHW+L+A R QRD++LSSLRMLIVADGANPWSISSCDAFLNVFQS+
Sbjct: 597  CFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSR 656

Query: 642  GLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTV 701
            GLR EVICPCASSPEALTVAIRRP D    PP + VLSM+GL+YGVIRVD+EEKLSVLTV
Sbjct: 657  GLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTV 716

Query: 702  QDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMT 761
            QDVG VMPGA +C VK +G P LC+TDE+GE+CV + ATGT+YYGL G+TKN FE  P+T
Sbjct: 717  QDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVT 776

Query: 762  SSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKF 821
            + GAPI + PF RTGLLGF+GP  LVF+VGK+DGLMV   RRHNADD+VATALAVEPMKF
Sbjct: 777  TGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKF 836

Query: 822  VYRGRIAVFSVTVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVP 881
            VYRGRIAVFSVTVLHD+RIV+VAEQRPD++EEDSFQWMSRVLQAIDSIHQVGVYCLALVP
Sbjct: 837  VYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVP 896

Query: 882  ANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVG 941
            ANTLPK PLGGIH+SETKQ FLEG+LHPCNVLMCPHTCVTNLPKPRQKQPE+GPAS++VG
Sbjct: 897  ANTLPKAPLGGIHISETKQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVG 956

Query: 942  NLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANS 1001
            NLV+GKRIAQASGR+L  +ED+DQARKFLFL++VLQWRA TTPDH L+ LLN +G + ++
Sbjct: 957  NLVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTST 1016

Query: 1002 LTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPH 1061
             TCVQLHKRAE++A  LME+G L  GDHVALVYPPG+DLIAAFYGCLY GCVP+TVRPPH
Sbjct: 1017 ATCVQLHKRAERVAAALMEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPH 1076

Query: 1062 PQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKR 1121
            PQN+ TTLPTVKMIVEVS+SAC++TTQ + +LLRS+EAAAAVD+RTWP ILDTDD+PKK+
Sbjct: 1077 PQNLGTTLPTVKMIVEVSKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKK 1136

Query: 1122 PAQICKPCNPDTLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLD 1181
             A + +P +PD LAYLDFSVSTTG+LAGVKMSHAATSA CRSIKLQCELYPSR++AICLD
Sbjct: 1137 IASVFRPPSPDVLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQCELYPSRQIAICLD 1196

Query: 1182 PYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTK 1241
            PYCGLGF LWCLCSVYSGHQS+L+PP ELE+N +LWL AVSQYK R TFCSYSVME+CTK
Sbjct: 1197 PYCGLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARVTFCSYSVMEMCTK 1256

Query: 1242 GLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRV 1301
            GLG+QT  L+ +G++LS VRTC+VVAEERPRIALTQSFSKLFKDLGL  RAVST+FGCRV
Sbjct: 1257 GLGAQTGVLRMKGVNLSCVRTCMVVAEERPRIALTQSFSKLFKDLGLPARAVSTTFGCRV 1316

Query: 1302 NLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE 1361
            N+AICLQGT+GPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGV++IIA+ E
Sbjct: 1317 NVAICLQGTAGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTE 1376

Query: 1362 TKGPLGDSHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFL 1421
            TKGPLGDSHLGEIWV S HNA+GY+T+YG+E+L +DHF++RLSFGDTQTIWARTGYLGFL
Sbjct: 1377 TKGPLGDSHLGEIWVSSPHNATGYYTVYGEEALHADHFSARLSFGDTQTIWARTGYLGFL 1436

Query: 1422 RRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNL 1481
            RRTELTDA+G RHDALYVVG+LDE +ELRGMRYHPIDIETSVIRAH+S+ ECAVFTWTNL
Sbjct: 1437 RRTELTDASGGRHDALYVVGSLDETLELRGMRYHPIDIETSVIRAHRSIAECAVFTWTNL 1496

Query: 1482 LVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDG 1541
            LVVVVELDG EQ+ALDLV LVTNVVLEEHYL+VGVVV+VD GVIPINSRGEKQRMHLRDG
Sbjct: 1497 LVVVVELDGLEQDALDLVALVTNVVLEEHYLVVGVVVIVDPGVIPINSRGEKQRMHLRDG 1556

Query: 1542 FLADQLDPIYVAYNM 1556
            FLADQLDPIYVAYNM
Sbjct: 1557 FLADQLDPIYVAYNM 1571


>gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]
          Length = 1567

 Score = 2384 bits (6178), Expect = 0.0
 Identities = 1167/1575 (74%), Positives = 1347/1575 (85%), Gaps = 27/1575 (1%)

Query: 1    MADRS--LEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQAL 58
            MADR   LE   LP EVR  LAELELELSEGDITQKGYEKKR+KL+  Y+P    +D +L
Sbjct: 1    MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 59   PQERRAP---VTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSK 115
              E R P    T ++A +  + R + SRDER+RSDVHTEAVQAALAK+KERKM  PMPSK
Sbjct: 61   QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM--PMPSK 118

Query: 116  RRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTS- 174
            RRS++V +S++ YTPPDTSS SEDEGS++   + T T  Q   ++E W+ + I GS+TS 
Sbjct: 119  RRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSS 178

Query: 175  -------------TTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQV 221
                         TT+ S+  + G+ A   LA + A THI+ HSAPPDVTT   EHS   
Sbjct: 179  SASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSY-F 237

Query: 222  ERPQGSTGSRTAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDF 281
            ERPQ ++  R+ P+  +  ++ET DGVPV+SRVS+KIQQL+NTLKRPKRPPL+EFFVDDF
Sbjct: 238  ERPQVAS-VRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDF 296

Query: 282  EELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMD 341
            EELLE    DPNQPKPEG++   +RGE L      PPSL A LQRWGT  PK+PCLT +D
Sbjct: 297  EELLE----DPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALD 352

Query: 342  TNGKPLYILTYGKLWTRSMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFY 401
            T GK +Y LTYGKLW+RS+K+AY++L+KL +K EP+++PGDRVALVFPN+DP  FM AFY
Sbjct: 353  TTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFY 412

Query: 402  GCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFK 461
            GCLLAE+VPVPIEVPLTRKDAGSQQ+GFLLGSCGV +ALT+DAC KGLPK+ TGE+  FK
Sbjct: 413  GCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFK 472

Query: 462  GWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHC 521
            GWP L W V + KHL+KPP+DW P  +D    TAYIEYKT K+GS +GVTV+  +LL  C
Sbjct: 473  GWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQC 532

Query: 522  QALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKV 581
            +ALTQACGY+EAET+ NVLDFK+D GLWHG+LTSVMN MHV+S+PY+LMK NPLSWIQKV
Sbjct: 533  RALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKV 592

Query: 582  CQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSK 641
            C YKA+ A VKSRDMHW+L+A R QRD++LSSLRMLIVADGANPWSISSCDAFLNVFQS+
Sbjct: 593  CFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSR 652

Query: 642  GLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTV 701
            GLR EVICPCASSPEALTVAIRRP D    PP + VLSM+GL+YGVIRVD+EEKLSVLTV
Sbjct: 653  GLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTV 712

Query: 702  QDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMT 761
            QDVG VMPGA +C VK +G P LC+TDE+GE+CV + ATGT+YYGL G+TKN FE  P+T
Sbjct: 713  QDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVT 772

Query: 762  SSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKF 821
            + GAPI + PF RTGLLGF+GP  LVF+VGK+DGLMV   RRHNADD+VATALAVEPMKF
Sbjct: 773  TGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKF 832

Query: 822  VYRGRIAVFSVTVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVP 881
            VYRGRIAVFSVTVLHD+RIV+VAEQRPD++EEDSFQWMSRVLQAIDSIHQVGVYCLALVP
Sbjct: 833  VYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVP 892

Query: 882  ANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVG 941
            ANTLPK PLGGIH+SETKQ FLEG+LHPCNVLMCPHTCVTNLPKPRQKQPE+GPAS++VG
Sbjct: 893  ANTLPKAPLGGIHISETKQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVG 952

Query: 942  NLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANS 1001
            NLV+GKRIAQASGR+L  +ED+DQARKFLFL++VLQWRA TTPDH L+ LLN +G + ++
Sbjct: 953  NLVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTST 1012

Query: 1002 LTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPH 1061
             TCVQLHKRAE++A  LME+G L  GDHVALVYPPG+DLIAAFYGCLY GCVP+TVRPPH
Sbjct: 1013 ATCVQLHKRAERVAAALMEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPH 1072

Query: 1062 PQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKR 1121
            PQN+ TTLPTVKMIVEVS+SAC++TTQ + +LLRS+EAAAAVD+RTWP ILDTDD+PKK+
Sbjct: 1073 PQNLGTTLPTVKMIVEVSKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKK 1132

Query: 1122 PAQICKPCNPDTLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLD 1181
             A + +P +PD LAYLDFSVSTTG+LAGVKMSHAATSA CRSIKLQCELYPSR++AICLD
Sbjct: 1133 IASVFRPPSPDVLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQCELYPSRQIAICLD 1192

Query: 1182 PYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTK 1241
            PYCGLGF LWCLCSVYSGHQS+L+PP ELE+N +LWL AVSQYK R TFCSYSVME+CTK
Sbjct: 1193 PYCGLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARVTFCSYSVMEMCTK 1252

Query: 1242 GLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRV 1301
            GLG+QT  L+ +G++LS VRTC+VVAEERPRIALTQSFSKLFKDLGL  RAVST+FGCRV
Sbjct: 1253 GLGAQTGVLRMKGVNLSCVRTCMVVAEERPRIALTQSFSKLFKDLGLPARAVSTTFGCRV 1312

Query: 1302 NLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE 1361
            N+AICLQGT+GPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGV++IIA+ E
Sbjct: 1313 NVAICLQGTAGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTE 1372

Query: 1362 TKGPLGDSHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFL 1421
            TKGPLGDSHLGEIWV S HNA+GY+T+YG+E+L +DHF++RLSFGDTQTIWARTGYLGFL
Sbjct: 1373 TKGPLGDSHLGEIWVSSPHNATGYYTVYGEEALHADHFSARLSFGDTQTIWARTGYLGFL 1432

Query: 1422 RRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNL 1481
            RRTELTDA+G RHDALYVVG+LDE +ELRGMRYHPIDIETSVIRAH+S+ ECAVFTWTNL
Sbjct: 1433 RRTELTDASGGRHDALYVVGSLDETLELRGMRYHPIDIETSVIRAHRSIAECAVFTWTNL 1492

Query: 1482 LVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDG 1541
            LVVVVELDG EQ+ALDLV LVTNVVLEEHYL+VGVVV+VD GVIPINSRGEKQRMHLRDG
Sbjct: 1493 LVVVVELDGLEQDALDLVALVTNVVLEEHYLVVGVVVIVDPGVIPINSRGEKQRMHLRDG 1552

Query: 1542 FLADQLDPIYVAYNM 1556
            FLADQLDPIYVAYNM
Sbjct: 1553 FLADQLDPIYVAYNM 1567


>gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo sapiens]
          Length = 1576

 Score = 2347 bits (6082), Expect = 0.0
 Identities = 1145/1576 (72%), Positives = 1331/1576 (84%), Gaps = 20/1576 (1%)

Query: 1    MADRSLEGM-----ALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVD 55
            MA+R LE       ALP EVRA+LAELELELSEGDITQKGYEKKRSKL+  Y PQ    D
Sbjct: 1    MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60

Query: 56   QALPQE-RRAPVTPSSA-----SRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMA 109
             A+ +E R     PS+A     S+YHR RS G+RDERYRSD+HTEAVQAALAKHKE+KMA
Sbjct: 61   SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120

Query: 110  VPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIH 169
            +PMP+KRRS  VQ+  DA TPPDTSS SEDEGS++  +  +    Q   N E WI+++I 
Sbjct: 121  LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180

Query: 170  GSTTSTTSSSSTQSGG-SGAAHRLADVMAQTHIENHSAPPDVTTYTSEHS-------IQV 221
            GS+TS+++SS+   G   G +  LADV A T IEN SAPPDVTT TS  S         +
Sbjct: 181  GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANI 240

Query: 222  ERPQGSTGSRTAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDF 281
            + P              + LM+T DGVPVSSRVS KIQQL+NTLKRPKRPPL+EFFVDD 
Sbjct: 241  DLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS 300

Query: 282  EELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMD 341
            EE++EV QPDPNQPKPEG QM  ++GE LGV+ NWPP+LE+ALQRWGT   K  CLT +D
Sbjct: 301  EEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALD 360

Query: 342  TNGKPLYILTYGKLWTRSMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFY 401
              GKP+Y LTYGKLW+RS+K+AY++L+KLGTK EP+++PGDRVALV+PNNDP  FM AFY
Sbjct: 361  MTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFY 420

Query: 402  GCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFK 461
            GCLLAEV+PVPIEVPLTRKDAG QQIGFLLGSCG+ +ALTS+ C KGLPK+  GEI QFK
Sbjct: 421  GCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKGLPKTQNGEIVQFK 480

Query: 462  GWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHC 521
            GWP+L W VT+SK+LSKPP+DW PHI  A  + AYIEYKT K+GSV+GVTV+R A+L+HC
Sbjct: 481  GWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHC 540

Query: 522  QALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKV 581
            QAL+QAC Y+E ETIVNVLDFKKD GLWHG+  +VMN MH IS+PYS+MK  PLSW+Q+V
Sbjct: 541  QALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRV 600

Query: 582  CQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSK 641
              +KAKVA VK RD+HWA++AHRDQRD++LSSLRMLIV DGANPWS+SSCDAFL++FQS 
Sbjct: 601  HAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSH 660

Query: 642  GLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTV 701
            GL+ E ICPCA+S EA+TVAIRRP       PGR +LSM+GL+YGVIRV++E+K S LTV
Sbjct: 661  GLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSALTV 720

Query: 702  QDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMT 761
            QDVG VMPG +MC VKPDG PQLC+TDEIGE+CV +   G  Y+GL+G+TKNTFEV P+ 
Sbjct: 721  QDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVN 780

Query: 762  SSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKF 821
            S+G+P+ + PFIR+GLLGFVGPG LVFVVGKMDGL++VSGRRHNADDIVAT LAVE +K 
Sbjct: 781  SAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKT 840

Query: 822  VYRGRIAVFSVTVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVP 881
            VYRGRIAVFSV+V +DERIV+VAEQRPD++EEDSFQWMSRVLQAIDSIHQVGVYCLALVP
Sbjct: 841  VYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVP 900

Query: 882  ANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVG 941
            ANTLPKTPLGGIH+S+TKQLFLEGSLHPCN+LMCPHTCVTNLPKPRQKQP +GPASVMVG
Sbjct: 901  ANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQKQPGVGPASVMVG 960

Query: 942  NLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANS 1001
            NLV+GKRIAQA+GRDLGQIE+ND  RK  FL+E+LQWRAQ TPDH+L+ LLN +G    +
Sbjct: 961  NLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVLFMLLNAKGTTVCT 1020

Query: 1002 LTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPH 1061
             +C+QLHKRAE+IA +L ++GHL  GD+V L+YPPGI+LIAAFYGCLYAGC+P+TVRPPH
Sbjct: 1021 ASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPH 1080

Query: 1062 PQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKR 1121
             QN+  TLPTV+MIV+VS++AC++T+Q + +LLRSREAAAAVDV+TWP I+DTDDLP+KR
Sbjct: 1081 AQNLTATLPTVRMIVDVSKAACILTSQTLMRLLRSREAAAAVDVKTWPTIIDTDDLPRKR 1140

Query: 1122 PAQICKPCNPDTLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLD 1181
              Q+ KP  P+ LAYLDFSVSTTGML GVKMSH+A +A CR+IKLQCELY SR++AICLD
Sbjct: 1141 LPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQCELYSSRQIAICLD 1200

Query: 1182 PYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTK 1241
            PYCGLGF LWCLCSVYSGHQS+LIPP ELE N  LWL  V+QYK+RDTFCSYSVMELCTK
Sbjct: 1201 PYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLSTVNQYKIRDTFCSYSVMELCTK 1260

Query: 1242 GLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRV 1301
            GLG+Q E LK RG++LS VRTCVVVAEERPR+AL QSFSKLFKD+GL PRAVST+FG RV
Sbjct: 1261 GLGNQVEVLKTRGINLSCVRTCVVVAEERPRVALQQSFSKLFKDIGLSPRAVSTTFGSRV 1320

Query: 1302 NLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE 1361
            N+AICLQGTSGPDPTTVYVD+++LRHDRVRLVERG+P SL L ESGKILPGV+++I NPE
Sbjct: 1321 NVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE 1380

Query: 1362 TKGPLGDSHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGD-TQTIWARTGYLGF 1420
            TKGP+GDSHLGEIWV+S H ASGY+TIY  E+LQ+DHFN+RLSFGD  QT+WARTGYLGF
Sbjct: 1381 TKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGF 1440

Query: 1421 LRRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTN 1480
            +RRTELT A GERHDALYVVGALDE +ELRG+RYHPIDIETSV R H+S+ ECAVFTWTN
Sbjct: 1441 VRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECAVFTWTN 1500

Query: 1481 LLVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRD 1540
            LLVVVVEL GSEQEALDLVPLVTNVVLEEHYLIVGVVVVVD GVIPINSRGEKQRMHLRD
Sbjct: 1501 LLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQRMHLRD 1560

Query: 1541 GFLADQLDPIYVAYNM 1556
             FLADQLDPIYVAYNM
Sbjct: 1561 SFLADQLDPIYVAYNM 1576


>gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens]
          Length = 1110

 Score = 1593 bits (4124), Expect = 0.0
 Identities = 774/1089 (71%), Positives = 909/1089 (83%), Gaps = 18/1089 (1%)

Query: 77   RRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSG 136
            R S    +     DVHTEAVQAALAK+KERKM  PMPSKRRS++V +S++ YTPPDTSS 
Sbjct: 18   RESLAELELELSEDVHTEAVQAALAKYKERKM--PMPSKRRSVLVHSSVETYTPPDTSSA 75

Query: 137  SEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTS--------------TTSSSSTQ 182
            SEDEGS++   + T T  Q   ++E W+ + I GS+TS              TT+ S+  
Sbjct: 76   SEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAA 135

Query: 183  SGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELM 242
            + G+ A   LA + A THI+ HSAPPDVTT   EHS   ERPQ ++  R+ P+  +  ++
Sbjct: 136  TPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSY-FERPQVAS-VRSVPRGCSGSML 193

Query: 243  ETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQM 302
            ET DGVPV+SRVS+KIQQL+NTLKRPKRPPL+EFFVDDFEELLEVQQPDPNQPKPEG++ 
Sbjct: 194  ETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSET 253

Query: 303  LAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKV 362
              +RGE L      PPSL A LQRWGT  PK+PCLT +DT GK +Y LTYGKLW+RS+K+
Sbjct: 254  SVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKL 313

Query: 363  AYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDA 422
            AY++L+KL +K EP+++PGDRVALVFPN+DP  FM AFYGCLLAE+VPVPIEVPLTRKDA
Sbjct: 314  AYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDA 373

Query: 423  GSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRD 482
            GSQQ+GFLLGSCGV +ALT+DAC KGLPK+ TGE+  FKGWP L W V + KHL+KPP+D
Sbjct: 374  GSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKD 433

Query: 483  WFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDF 542
            W P  +D    TAYIEYKT K+GS +GVTV+  +LL  C+ALTQACGY+EAET+ NVLDF
Sbjct: 434  WHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDF 493

Query: 543  KKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVA 602
            K+D GLWHG+LTSVMN MHV+S+PY+LMK NPLSWIQKVC YKA+ A VKSRDMHW+L+A
Sbjct: 494  KRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLA 553

Query: 603  HRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAI 662
             R QRD++LSSLRMLIVADGANPWSISSCDAFLNVFQS+GLR EVICPCASSPEALTVAI
Sbjct: 554  QRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAI 613

Query: 663  RRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVP 722
            RRP D    PP + VLSM+GL+YGVIRVD+EEKLSVLTVQDVG VMPGA +C VK +G P
Sbjct: 614  RRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTP 673

Query: 723  QLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVG 782
             LC+TDE+GE+CV + ATGT+YYGL G+TKN FE  P+T+ GAPI + PF RTGLLGF+G
Sbjct: 674  YLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIG 733

Query: 783  PGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVI 842
            P  LVF+VGK+DGLMV   RRHNADD+VATALAVEPMKFVYRGRIAVFSVTVLHD+RIV+
Sbjct: 734  PDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVL 793

Query: 843  VAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLF 902
            VAEQRPD++EEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPK PLGGIH+SETKQ F
Sbjct: 794  VAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRF 853

Query: 903  LEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIED 962
            LEG+LHPCNVLMCPHTCVTNLPKPRQKQPE+GPAS++VGNLV+GKRIAQASGR+L  +ED
Sbjct: 854  LEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRIAQASGRELAHLED 913

Query: 963  NDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERG 1022
            +DQARKFLFL++VLQWRA TTPDH L+ LLN +G + ++ TCVQLHKRAE++A  LME+G
Sbjct: 914  SDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEKG 973

Query: 1023 HLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSA 1082
             L  GDHVALVYPPG+DLIAAFYGCLY GCVP+TVRPPHPQN+ TTLPTVKMIVEVS+SA
Sbjct: 974  RLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEVSKSA 1033

Query: 1083 CLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVS 1142
            C++TTQ + +LLRS+EAAAAVD+RTWP ILDTDD+PKK+ A + +P +PD LAYLDFSVS
Sbjct: 1034 CVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDDIPKKKIASVFRPPSPDVLAYLDFSVS 1093

Query: 1143 TTGMLAGVK 1151
            TTG+LAGVK
Sbjct: 1094 TTGILAGVK 1102



 Score =  127 bits (319), Expect = 8e-29
 Identities = 159/664 (23%), Positives = 260/664 (39%), Gaps = 76/664 (11%)

Query: 924  PKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTT 983
            P P Q +PE    SV+ G  ++                     R    L+ + +W   T 
Sbjct: 241  PDPNQPKPEGSETSVLRGEPLTA-----------------GVPRPPSLLATLQRW-GTTQ 282

Query: 984  PDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMER------GHLQDGDHVALVYPPG 1037
            P     T L+  G    +LT  +L  R+ K+A  L+ +        L+ GD VALV+P  
Sbjct: 283  PKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNS 342

Query: 1038 --IDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLR 1095
              +  + AFYGCL A  VP+ +  P  +  A +   V  ++        +TT    K L 
Sbjct: 343  DPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGS-QQVGFLLGSCGVFLALTTDACQKGLP 401

Query: 1096 SREAAAAVDVRTWP----LILDTDDLPKKRPAQICKPCNPDT---LAYLDFSVSTTGMLA 1148
              +       + WP    L++D   L K  P +   P   DT    AY+++  S  G   
Sbjct: 402  KAQTGEVAAFKGWPPLSWLVIDGKHLAK--PPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 459

Query: 1149 GVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPS 1208
            GV +SHA+  A CR++   C    +  +   LD     G     L SV +    + +P +
Sbjct: 460  GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 519

Query: 1209 ELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAE 1268
             ++ NP  W+  V  YK R        M         Q      R + LS +R  +V   
Sbjct: 520  LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVADG 573

Query: 1269 ERP-RIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ---GTSGPDPTTVYVDMRA 1324
              P  I+   +F  +F+  GL P  +         L + ++      GP P    + M  
Sbjct: 574  ANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNG 633

Query: 1325 LRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE-TKGPLGDSHLGEIWVHSAHNAS 1383
            L +  +R+        L + + G+++PG  + +   E T        +GEI V S+   +
Sbjct: 634  LSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGT 693

Query: 1384 GYFTIYGDESLQSDHFNS-RLSFGDTQTI---WARTGYLGFLRRTELTDANGERHDALYV 1439
             Y+ + G   +  + F +  ++ G        + RTG LGF+    L          +++
Sbjct: 694  AYYGLLG---ITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNL----------VFI 740

Query: 1440 VGALDEAMELRGMRYHPIDIETSVIRAHKSVT-----ECAVFTWTNL----LVVVVEL-- 1488
            VG LD  M + G+R H  D   +   A + +        AVF+ T L    +V+V E   
Sbjct: 741  VGKLDGLM-VTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRP 799

Query: 1489 DGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLD 1548
            D SE+++   +  V   +   H + V  + +V    +P    G       +  FL   L 
Sbjct: 800  DASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGTLH 859

Query: 1549 PIYV 1552
            P  V
Sbjct: 860  PCNV 863


>gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens]
          Length = 889

 Score = 1198 bits (3099), Expect = 0.0
 Identities = 598/883 (67%), Positives = 708/883 (80%), Gaps = 23/883 (2%)

Query: 1   MADRS--LEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQAL 58
           MADR   LE   LP EVR  LAELELELSEGDITQKGYEKKR+KL+  Y+P    +D +L
Sbjct: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 59  PQERRAP---VTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSK 115
             E R P    T ++A +  + R + SRDER+RSDVHTEAVQAALAK+KERKM  PMPSK
Sbjct: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM--PMPSK 118

Query: 116 RRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTS- 174
           RRS++V +S++ YTPPDTSS SEDEGS++   + T T  Q   ++E W+ + I GS+TS 
Sbjct: 119 RRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSS 178

Query: 175 -------------TTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQV 221
                        TT+ S+  + G+ A   LA + A THI+ HSAPPDVTT   EHS   
Sbjct: 179 SASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSY-F 237

Query: 222 ERPQGSTGSRTAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDF 281
           ERPQ ++  R+ P+  +  ++ET DGVPV+SRVS+KIQQL+NTLKRPKRPPL+EFFVDDF
Sbjct: 238 ERPQVAS-VRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDF 296

Query: 282 EELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMD 341
           EELLEVQQPDPNQPKPEG++   +RGE L      PPSL A LQRWGT  PK+PCLT +D
Sbjct: 297 EELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALD 356

Query: 342 TNGKPLYILTYGKLWTRSMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFY 401
           T GK +Y LTYGKLW+RS+K+AY++L+KL +K EP+++PGDRVALVFPN+DP  FM AFY
Sbjct: 357 TTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFY 416

Query: 402 GCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFK 461
           GCLLAE+VPVPIEVPLTRKDAGSQQ+GFLLGSCGV +ALT+DAC KGLPK+ TGE+  FK
Sbjct: 417 GCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFK 476

Query: 462 GWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHC 521
           GWP L W V + KHL+KPP+DW P  +D    TAYIEYKT K+GS +GVTV+  +LL  C
Sbjct: 477 GWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQC 536

Query: 522 QALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKV 581
           +ALTQACGY+EAET+ NVLDFK+D GLWHG+LTSVMN MHV+S+PY+LMK NPLSWIQKV
Sbjct: 537 RALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKV 596

Query: 582 CQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSK 641
           C YKA+ A VKSRDMHW+L+A R QRD++LSSLRMLIVADGANPWSISSCDAFLNVFQS+
Sbjct: 597 CFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSR 656

Query: 642 GLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTV 701
           GLR EVICPCASSPEALTVAIRRP D    PP + VLSM+GL+YGVIRVD+EEKLSVLTV
Sbjct: 657 GLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTV 716

Query: 702 QDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMT 761
           QDVG VMPGA +C VK +G P LC+TDE+GE+CV + ATGT+YYGL G+TKN FE  P+T
Sbjct: 717 QDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVT 776

Query: 762 SSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKF 821
           + GAPI + PF RTGLLGF+GP  LVF+VGK+DGLMV   RRHNADD+VATALAVEPMKF
Sbjct: 777 TGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKF 836

Query: 822 VYRGRIAVFSVTVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQ 864
           VYRGRIAVFSVTVLHD+RIV+VAEQRPD++EEDSFQWMSRVLQ
Sbjct: 837 VYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQ 879



 Score =  121 bits (304), Expect = 5e-27
 Identities = 150/617 (24%), Positives = 245/617 (39%), Gaps = 76/617 (12%)

Query: 924  PKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTT 983
            P P Q +PE    SV+ G  ++                     R    L+ + +W   T 
Sbjct: 305  PDPNQPKPEGSETSVLRGEPLTA-----------------GVPRPPSLLATLQRW-GTTQ 346

Query: 984  PDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMER------GHLQDGDHVALVYPPG 1037
            P     T L+  G    +LT  +L  R+ K+A  L+ +        L+ GD VALV+P  
Sbjct: 347  PKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNS 406

Query: 1038 --IDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLR 1095
              +  + AFYGCL A  VP+ +  P  +  A +   V  ++        +TT    K L 
Sbjct: 407  DPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGS-QQVGFLLGSCGVFLALTTDACQKGLP 465

Query: 1096 SREAAAAVDVRTWP----LILDTDDLPKKRPAQICKPCNPDT---LAYLDFSVSTTGMLA 1148
              +       + WP    L++D   L K  P +   P   DT    AY+++  S  G   
Sbjct: 466  KAQTGEVAAFKGWPPLSWLVIDGKHLAK--PPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 523

Query: 1149 GVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPS 1208
            GV +SHA+  A CR++   C    +  +   LD     G     L SV +    + +P +
Sbjct: 524  GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 583

Query: 1209 ELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAE 1268
             ++ NP  W+  V  YK R        M         Q      R + LS +R  +V   
Sbjct: 584  LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVADG 637

Query: 1269 ERP-RIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ---GTSGPDPTTVYVDMRA 1324
              P  I+   +F  +F+  GL P  +         L + ++      GP P    + M  
Sbjct: 638  ANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNG 697

Query: 1325 LRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE-TKGPLGDSHLGEIWVHSAHNAS 1383
            L +  +R+        L + + G+++PG  + +   E T        +GEI V S+   +
Sbjct: 698  LSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGT 757

Query: 1384 GYFTIYGDESLQSDHFNS-RLSFGDTQTI---WARTGYLGFLRRTELTDANGERHDALYV 1439
             Y+ + G   +  + F +  ++ G        + RTG LGF+    L          +++
Sbjct: 758  AYYGLLG---ITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNL----------VFI 804

Query: 1440 VGALDEAMELRGMRYHPIDIETSVIRAHKSVT-----ECAVFTWTNL----LVVVVEL-- 1488
            VG LD  M + G+R H  D   +   A + +        AVF+ T L    +V+V E   
Sbjct: 805  VGKLDGLM-VTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRP 863

Query: 1489 DGSEQEALDLVPLVTNV 1505
            D SE+++   +  V  V
Sbjct: 864  DASEEDSFQWMSRVLQV 880


>gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens]
          Length = 841

 Score = 1130 bits (2922), Expect = 0.0
 Identities = 564/845 (66%), Positives = 670/845 (79%), Gaps = 23/845 (2%)

Query: 1   MADRS--LEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQAL 58
           MADR   LE   LP EVR  LAELELELSEGDITQKGYEKKR+KL+  Y+P    +D +L
Sbjct: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 59  PQERRAP---VTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSK 115
             E R P    T ++A +  + R + SRDER+RSDVHTEAVQAALAK+KERKM  PMPSK
Sbjct: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM--PMPSK 118

Query: 116 RRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTS- 174
           RRS++V +S++ YTPPDTSS SEDEGS++   + T T  Q   ++E W+ + I GS+TS 
Sbjct: 119 RRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSS 178

Query: 175 -------------TTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQV 221
                        TT+ S+  + G+ A   LA + A THI+ HSAPPDVTT   EHS   
Sbjct: 179 SASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSY-F 237

Query: 222 ERPQGSTGSRTAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDF 281
           ERPQ ++  R+ P+  +  ++ET DGVPV+SRVS+KIQQL+NTLKRPKRPPL+EFFVDDF
Sbjct: 238 ERPQVAS-VRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDF 296

Query: 282 EELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMD 341
           EELLEVQQPDPNQPKPEG++   +RGE L      PPSL A LQRWGT  PK+PCLT +D
Sbjct: 297 EELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALD 356

Query: 342 TNGKPLYILTYGKLWTRSMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFY 401
           T GK +Y LTYGKLW+RS+K+AY++L+KL +K EP+++PGDRVALVFPN+DP  FM AFY
Sbjct: 357 TTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFY 416

Query: 402 GCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFK 461
           GCLLAE+VPVPIEVPLTRKDAGSQQ+GFLLGSCGV +ALT+DAC KGLPK+ TGE+  FK
Sbjct: 417 GCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFK 476

Query: 462 GWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHC 521
           GWP L W V + KHL+KPP+DW P  +D    TAYIEYKT K+GS +GVTV+  +LL  C
Sbjct: 477 GWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQC 536

Query: 522 QALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKV 581
           +ALTQACGY+EAET+ NVLDFK+D GLWHG+LTSVMN MHV+S+PY+LMK NPLSWIQKV
Sbjct: 537 RALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKV 596

Query: 582 CQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSK 641
           C YKA+ A VKSRDMHW+L+A R QRD++LSSLRMLIVADGANPWSISSCDAFLNVFQS+
Sbjct: 597 CFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSR 656

Query: 642 GLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTV 701
           GLR EVICPCASSPEALTVAIRRP D    PP + VLSM+GL+YGVIRVD+EEKLSVLTV
Sbjct: 657 GLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTV 716

Query: 702 QDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMT 761
           QDVG VMPGA +C VK +G P LC+TDE+GE+CV + ATGT+YYGL G+TKN FE  P+T
Sbjct: 717 QDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVT 776

Query: 762 SSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKF 821
           + GAPI + PF RTGLLGF+GP  LVF+VGK+DGLMV   RRHNADD+VATALAVEPMKF
Sbjct: 777 TGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKF 836

Query: 822 VYRGR 826
           VYRGR
Sbjct: 837 VYRGR 841



 Score =  120 bits (300), Expect = 1e-26
 Identities = 136/559 (24%), Positives = 221/559 (39%), Gaps = 65/559 (11%)

Query: 924  PKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTT 983
            P P Q +PE    SV+ G  ++                     R    L+ + +W   T 
Sbjct: 305  PDPNQPKPEGSETSVLRGEPLTA-----------------GVPRPPSLLATLQRW-GTTQ 346

Query: 984  PDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMER------GHLQDGDHVALVYPPG 1037
            P     T L+  G    +LT  +L  R+ K+A  L+ +        L+ GD VALV+P  
Sbjct: 347  PKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNS 406

Query: 1038 --IDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLR 1095
              +  + AFYGCL A  VP+ +  P  +  A +   V  ++        +TT    K L 
Sbjct: 407  DPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGS-QQVGFLLGSCGVFLALTTDACQKGLP 465

Query: 1096 SREAAAAVDVRTWP----LILDTDDLPKKRPAQICKPCNPDT---LAYLDFSVSTTGMLA 1148
              +       + WP    L++D   L K  P +   P   DT    AY+++  S  G   
Sbjct: 466  KAQTGEVAAFKGWPPLSWLVIDGKHLAK--PPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 523

Query: 1149 GVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPS 1208
            GV +SHA+  A CR++   C    +  +   LD     G     L SV +    + +P +
Sbjct: 524  GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 583

Query: 1209 ELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAE 1268
             ++ NP  W+  V  YK R        M         Q      R + LS +R  +V   
Sbjct: 584  LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVADG 637

Query: 1269 ERP-RIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ---GTSGPDPTTVYVDMRA 1324
              P  I+   +F  +F+  GL P  +         L + ++      GP P    + M  
Sbjct: 638  ANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNG 697

Query: 1325 LRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE-TKGPLGDSHLGEIWVHSAHNAS 1383
            L +  +R+        L + + G+++PG  + +   E T        +GEI V S+   +
Sbjct: 698  LSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGT 757

Query: 1384 GYFTIYGDESLQSDHFNS-RLSFGDTQTI---WARTGYLGFLRRTELTDANGERHDALYV 1439
             Y+ + G   +  + F +  ++ G        + RTG LGF+    L          +++
Sbjct: 758  AYYGLLG---ITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNL----------VFI 804

Query: 1440 VGALDEAMELRGMRYHPID 1458
            VG LD  M + G+R H  D
Sbjct: 805  VGKLDGLM-VTGVRRHNAD 822


>gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]
          Length = 798

 Score = 1079 bits (2790), Expect = 0.0
 Identities = 540/831 (64%), Positives = 643/831 (77%), Gaps = 38/831 (4%)

Query: 1   MADRS--LEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQAL 58
           MADR   LE   LP EVR  LAELELELSEGDITQKGYEKKR+KL+  Y+P    +D +L
Sbjct: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 59  PQERRAP---VTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSK 115
             E R P    T ++A +  + R + SRDER+RSDVHTEAVQAALAK+KERKM  PMPSK
Sbjct: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM--PMPSK 118

Query: 116 RRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTST 175
           RRS++V +S++ YTPPDTSS SEDEGS++   + T T  Q   ++E W+ + I GS+TS+
Sbjct: 119 RRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSS 178

Query: 176 TSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPK 235
           ++SS++   G             T   + +A P     T+   ++               
Sbjct: 179 SASSTSSHPGG----------RPTTAPSAAATPGAAATTALAGLEAH------------- 215

Query: 236 YGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQP 295
                   T  GVPV+SRVS+KIQQL+NTLKRPKRPPL+EFFVDDFEELLEVQQPDPNQP
Sbjct: 216 --------THIGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQP 267

Query: 296 KPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKL 355
           KPEG++   +RGE L      PPSL A LQRWGT  PK+PCLT +DT GK +Y LTYGKL
Sbjct: 268 KPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKL 327

Query: 356 WTRSMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEV 415
           W+RS+K+AY++L+KL +K EP+++PGDRVALVFPN+DP  FM AFYGCLLAE+VPVPIEV
Sbjct: 328 WSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEV 387

Query: 416 PLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKH 475
           PLTRKDAGSQQ+GFLLGSCGV +ALT+DAC KGLPK+ TGE+  FKGWP L W V + KH
Sbjct: 388 PLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKH 447

Query: 476 LSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAET 535
           L+KPP+DW P  +D    TAYIEYKT K+GS +GVTV+  +LL  C+ALTQACGY+EAET
Sbjct: 448 LAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAET 507

Query: 536 IVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRD 595
           + NVLDFK+D GLWHG+LTSVMN MHV+S+PY+LMK NPLSWIQKVC YKA+ A VKSRD
Sbjct: 508 LTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRD 567

Query: 596 MHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSP 655
           MHW+L+A R QRD++LSSLRMLIVADGANPWSISSCDAFLNVFQS+GLR EVICPCASSP
Sbjct: 568 MHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSP 627

Query: 656 EALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCS 715
           EALTVAIRRP D    PP + VLSM+GL+YGVIRVD+EEKLSVLTVQDVG VMPGA +C 
Sbjct: 628 EALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCV 687

Query: 716 VKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRT 775
           VK +G P LC+TDE+GE+CV + ATGT+YYGL G+TKN FE  P+T+ GAPI + PF RT
Sbjct: 688 VKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRT 747

Query: 776 GLLGFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGR 826
           GLLGF+GP  LVF+VGK+DGLMV   RRHNADD+VATALAVEPMKFVYRGR
Sbjct: 748 GLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGR 798



 Score =  120 bits (300), Expect = 1e-26
 Identities = 136/559 (24%), Positives = 221/559 (39%), Gaps = 65/559 (11%)

Query: 924  PKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTT 983
            P P Q +PE    SV+ G  ++                     R    L+ + +W   T 
Sbjct: 262  PDPNQPKPEGSETSVLRGEPLTA-----------------GVPRPPSLLATLQRW-GTTQ 303

Query: 984  PDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMER------GHLQDGDHVALVYPPG 1037
            P     T L+  G    +LT  +L  R+ K+A  L+ +        L+ GD VALV+P  
Sbjct: 304  PKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNS 363

Query: 1038 --IDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLR 1095
              +  + AFYGCL A  VP+ +  P  +  A +   V  ++        +TT    K L 
Sbjct: 364  DPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGS-QQVGFLLGSCGVFLALTTDACQKGLP 422

Query: 1096 SREAAAAVDVRTWP----LILDTDDLPKKRPAQICKPCNPDT---LAYLDFSVSTTGMLA 1148
              +       + WP    L++D   L K  P +   P   DT    AY+++  S  G   
Sbjct: 423  KAQTGEVAAFKGWPPLSWLVIDGKHLAK--PPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 480

Query: 1149 GVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPS 1208
            GV +SHA+  A CR++   C    +  +   LD     G     L SV +    + +P +
Sbjct: 481  GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 540

Query: 1209 ELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAE 1268
             ++ NP  W+  V  YK R        M         Q      R + LS +R  +V   
Sbjct: 541  LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVADG 594

Query: 1269 ERP-RIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ---GTSGPDPTTVYVDMRA 1324
              P  I+   +F  +F+  GL P  +         L + ++      GP P    + M  
Sbjct: 595  ANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNG 654

Query: 1325 LRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE-TKGPLGDSHLGEIWVHSAHNAS 1383
            L +  +R+        L + + G+++PG  + +   E T        +GEI V S+   +
Sbjct: 655  LSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGT 714

Query: 1384 GYFTIYGDESLQSDHFNS-RLSFGDTQTI---WARTGYLGFLRRTELTDANGERHDALYV 1439
             Y+ + G   +  + F +  ++ G        + RTG LGF+    L          +++
Sbjct: 715  AYYGLLG---ITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNL----------VFI 761

Query: 1440 VGALDEAMELRGMRYHPID 1458
            VG LD  M + G+R H  D
Sbjct: 762  VGKLDGLM-VTGVRRHNAD 779


>gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens]
          Length = 812

 Score = 1060 bits (2740), Expect = 0.0
 Identities = 529/802 (65%), Positives = 632/802 (78%), Gaps = 23/802 (2%)

Query: 1   MADRS--LEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQAL 58
           MADR   LE   LP EVR  LAELELELSEGDITQKGYEKKR+KL+  Y+P    +D +L
Sbjct: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 59  PQERRAP---VTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSK 115
             E R P    T ++A +  + R + SRDER+RSDVHTEAVQAALAK+KERKM  PMPSK
Sbjct: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM--PMPSK 118

Query: 116 RRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTS- 174
           RRS++V +S++ YTPPDTSS SEDEGS++   + T T  Q   ++E W+ + I GS+TS 
Sbjct: 119 RRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSS 178

Query: 175 -------------TTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQV 221
                        TT+ S+  + G+ A   LA + A THI+ HSAPPDVTT   EHS   
Sbjct: 179 SASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSY-F 237

Query: 222 ERPQGSTGSRTAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDF 281
           ERPQ ++  R+ P+  +  ++ET DGVPV+SRVS+KIQQL+NTLKRPKRPPL+EFFVDDF
Sbjct: 238 ERPQVAS-VRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDF 296

Query: 282 EELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMD 341
           EELLEVQQPDPNQPKPEG++   +RGE L      PPSL A LQRWGT  PK+PCLT +D
Sbjct: 297 EELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALD 356

Query: 342 TNGKPLYILTYGKLWTRSMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFY 401
           T GK +Y LTYGKLW+RS+K+AY++L+KL +K EP+++PGDRVALVFPN+DP  FM AFY
Sbjct: 357 TTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFY 416

Query: 402 GCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFK 461
           GCLLAE+VPVPIEVPLTRKDAGSQQ+GFLLGSCGV +ALT+DAC KGLPK+ TGE+  FK
Sbjct: 417 GCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFK 476

Query: 462 GWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHC 521
           GWP L W V + KHL+KPP+DW P  +D    TAYIEYKT K+GS +GVTV+  +LL  C
Sbjct: 477 GWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQC 536

Query: 522 QALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKV 581
           +ALTQACGY+EAET+ NVLDFK+D GLWHG+LTSVMN MHV+S+PY+LMK NPLSWIQKV
Sbjct: 537 RALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKV 596

Query: 582 CQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSK 641
           C YKA+ A VKSRDMHW+L+A R QRD++LSSLRMLIVADGANPWSISSCDAFLNVFQS+
Sbjct: 597 CFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSR 656

Query: 642 GLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTV 701
           GLR EVICPCASSPEALTVAIRRP D    PP + VLSM+GL+YGVIRVD+EEKLSVLTV
Sbjct: 657 GLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTV 716

Query: 702 QDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMT 761
           QDVG VMPGA +C VK +G P LC+TDE+GE+CV + ATGT+YYGL G+TKN FE  P+T
Sbjct: 717 QDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVT 776

Query: 762 SSGAPISEYPFIRTGLLGFVGP 783
           + GAPI + PF RTGLLGF+GP
Sbjct: 777 TGGAPIFDRPFTRTGLLGFIGP 798



 Score =  114 bits (285), Expect = 7e-25
 Identities = 126/522 (24%), Positives = 206/522 (39%), Gaps = 54/522 (10%)

Query: 924  PKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTT 983
            P P Q +PE    SV+ G  ++                     R    L+ + +W   T 
Sbjct: 305  PDPNQPKPEGSETSVLRGEPLTA-----------------GVPRPPSLLATLQRW-GTTQ 346

Query: 984  PDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMER------GHLQDGDHVALVYPPG 1037
            P     T L+  G    +LT  +L  R+ K+A  L+ +        L+ GD VALV+P  
Sbjct: 347  PKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNS 406

Query: 1038 --IDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLR 1095
              +  + AFYGCL A  VP+ +  P  +  A +   V  ++        +TT    K L 
Sbjct: 407  DPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGS-QQVGFLLGSCGVFLALTTDACQKGLP 465

Query: 1096 SREAAAAVDVRTWP----LILDTDDLPKKRPAQICKPCNPDT---LAYLDFSVSTTGMLA 1148
              +       + WP    L++D   L K  P +   P   DT    AY+++  S  G   
Sbjct: 466  KAQTGEVAAFKGWPPLSWLVIDGKHLAK--PPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 523

Query: 1149 GVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPS 1208
            GV +SHA+  A CR++   C    +  +   LD     G     L SV +    + +P +
Sbjct: 524  GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 583

Query: 1209 ELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAE 1268
             ++ NP  W+  V  YK R        M         Q      R + LS +R  +V   
Sbjct: 584  LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVADG 637

Query: 1269 ERP-RIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ---GTSGPDPTTVYVDMRA 1324
              P  I+   +F  +F+  GL P  +         L + ++      GP P    + M  
Sbjct: 638  ANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNG 697

Query: 1325 LRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE-TKGPLGDSHLGEIWVHSAHNAS 1383
            L +  +R+        L + + G+++PG  + +   E T        +GEI V S+   +
Sbjct: 698  LSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGT 757

Query: 1384 GYFTIYGDESLQSDHFNS-RLSFGDTQTI---WARTGYLGFL 1421
             Y+ + G   +  + F +  ++ G        + RTG LGF+
Sbjct: 758  AYYGLLG---ITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFI 796


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 38.9 bits (89), Expect = 0.039
 Identities = 24/86 (27%), Positives = 43/86 (50%)

Query: 133  TSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRL 192
            +SSGSE EG  +GD  G      G  N     S+A   +++S++SSSS+ S  S ++   
Sbjct: 2575 SSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSS 2634

Query: 193  ADVMAQTHIENHSAPPDVTTYTSEHS 218
            +   + +   + S+    ++ +S  S
Sbjct: 2635 SSSSSSSSSSSSSSSSSSSSSSSSSS 2660



 Score = 34.3 bits (77), Expect = 0.96
 Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 2/84 (2%)

Query: 124  SMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQS 183
            S  A +P  +SS S    S    S  + +SS  S +     S +   S++S++SSSS+ S
Sbjct: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--SSSSSSSSSSSSSSSSSSS 2663

Query: 184  GGSGAAHRLADVMAQTHIENHSAP 207
              S ++    D  +    ++ +AP
Sbjct: 2664 SSSSSSSSTTDEDSSCSSDDEAAP 2687


>gi|164663780 zinc finger protein 385B isoform 3 [Homo sapiens]
          Length = 369

 Score = 38.1 bits (87), Expect = 0.067
 Identities = 40/176 (22%), Positives = 71/176 (40%), Gaps = 9/176 (5%)

Query: 76  RRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSS 135
           R  S    +  Y+   H + V+A  A   + KM   +PSK  +    +        + S 
Sbjct: 63  RFNSDSQAEAHYKGSKHAKKVKALDATKNKPKM---VPSKDSAKANPSCSITPITGNNSD 119

Query: 136 GSEDEGSVQGDSQGTPTSSQ-GSINMEHWISQAIHGSTTSTTSSSSTQSG-----GSGAA 189
            SED+G ++  S   P+SS+ GS  ++   +    G+ TS + S++   G         A
Sbjct: 120 KSEDKGKLKASSSSQPSSSESGSFLLKSGTTPLPPGAATSPSKSTNGAPGTVVESEEEKA 179

Query: 190 HRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMETG 245
            +L          N  +  +     S+H   VE   G+   ++ P+ G+   M+ G
Sbjct: 180 KKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNG 235


>gi|164663778 zinc finger protein 385B isoform 2 [Homo sapiens]
          Length = 395

 Score = 38.1 bits (87), Expect = 0.067
 Identities = 40/176 (22%), Positives = 71/176 (40%), Gaps = 9/176 (5%)

Query: 76  RRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSS 135
           R  S    +  Y+   H + V+A  A   + KM   +PSK  +    +        + S 
Sbjct: 89  RFNSDSQAEAHYKGSKHAKKVKALDATKNKPKM---VPSKDSAKANPSCSITPITGNNSD 145

Query: 136 GSEDEGSVQGDSQGTPTSSQ-GSINMEHWISQAIHGSTTSTTSSSSTQSG-----GSGAA 189
            SED+G ++  S   P+SS+ GS  ++   +    G+ TS + S++   G         A
Sbjct: 146 KSEDKGKLKASSSSQPSSSESGSFLLKSGTTPLPPGAATSPSKSTNGAPGTVVESEEEKA 205

Query: 190 HRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMETG 245
            +L          N  +  +     S+H   VE   G+   ++ P+ G+   M+ G
Sbjct: 206 KKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNG 261


>gi|63029928 zinc finger protein 385B isoform 1 [Homo sapiens]
          Length = 471

 Score = 38.1 bits (87), Expect = 0.067
 Identities = 40/176 (22%), Positives = 71/176 (40%), Gaps = 9/176 (5%)

Query: 76  RRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSS 135
           R  S    +  Y+   H + V+A  A   + KM   +PSK  +    +        + S 
Sbjct: 165 RFNSDSQAEAHYKGSKHAKKVKALDATKNKPKM---VPSKDSAKANPSCSITPITGNNSD 221

Query: 136 GSEDEGSVQGDSQGTPTSSQ-GSINMEHWISQAIHGSTTSTTSSSSTQSG-----GSGAA 189
            SED+G ++  S   P+SS+ GS  ++   +    G+ TS + S++   G         A
Sbjct: 222 KSEDKGKLKASSSSQPSSSESGSFLLKSGTTPLPPGAATSPSKSTNGAPGTVVESEEEKA 281

Query: 190 HRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMETG 245
            +L          N  +  +     S+H   VE   G+   ++ P+ G+   M+ G
Sbjct: 282 KKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNG 337


>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
          Length = 416

 Score = 38.1 bits (87), Expect = 0.067
 Identities = 38/115 (33%), Positives = 47/115 (40%), Gaps = 14/115 (12%)

Query: 133 TSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRL 192
           +SSGS   GS  G S G+  +S GS             S  S+T SSS   GGSG  +  
Sbjct: 272 SSSGSSSGGSSGGSSGGSSGNSGGSRG-----DSGSESSWGSSTGSSSGNHGGSGGGN-- 324

Query: 193 ADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQG-STGSRTAPKYGNAELMETGD 246
                  H      P +    + E  IQ  R QG S+  R   K GN  L  +GD
Sbjct: 325 ------GHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGD 373


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 37.0 bits (84), Expect = 0.15
 Identities = 34/137 (24%), Positives = 55/137 (40%), Gaps = 3/137 (2%)

Query: 123 TSMDAYTPPDTSSGSEDEG-SVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSST 181
           TS  A T  ++ S +   G S   +S+ + TSS  S       S    G++T+T S SST
Sbjct: 308 TSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSST 367

Query: 182 QSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAEL 241
            S G+  A         +     +A    ++ TS  +      + ST S  A    N+E 
Sbjct: 368 TSSGTSTATNSESSTVSSGAS--TATTSESSTTSSGASTATNSESSTVSSGASTATNSES 425

Query: 242 METGDGVPVSSRVSAKI 258
             T  G   ++   + +
Sbjct: 426 STTSSGANTATNSGSSV 442



 Score = 36.2 bits (82), Expect = 0.25
 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 2/116 (1%)

Query: 142 SVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHI 201
           S+  +S+ + TSS  S       S    G++T+T S SST S  SGA+       + T  
Sbjct: 103 SIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTS--SGASTATNSDSSTTSS 160

Query: 202 ENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMETGDGVPVSSRVSAK 257
           E  +A    ++ TS  +      + ST S  A    N+E   T  G   ++   ++
Sbjct: 161 EASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESR 216



 Score = 35.4 bits (80), Expect = 0.43
 Identities = 42/148 (28%), Positives = 61/148 (41%), Gaps = 8/148 (5%)

Query: 123 TSMDAYTPPDT-SSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSST 181
           TS  A T  ++ SS +  E S   +S+ + TSS  S       S     ++T+T S SST
Sbjct: 143 TSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESST 202

Query: 182 QSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAEL 241
            S  SGA+         T     +A    ++ TS  +      + ST S  A    N+E 
Sbjct: 203 TS--SGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSES 260

Query: 242 METGDGVPV-----SSRVSAKIQQLVNT 264
             T  G        SS VS+ I  + N+
Sbjct: 261 STTSSGAGTATNSESSTVSSGISTVTNS 288



 Score = 35.0 bits (79), Expect = 0.57
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 13/89 (14%)

Query: 123 TSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQ 182
           TS  + T    S+ +  E S       T T+S+ S            G+ T+T S SS  
Sbjct: 392 TSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSS--------GANTATNSGSSVT 443

Query: 183 SGGSGAAHRLADVMAQTHIENHSAPPDVT 211
           S GSG A      +   H  +HSA   V+
Sbjct: 444 SAGSGTA-----ALTGMHTTSHSASTAVS 467



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 40/186 (21%), Positives = 67/186 (36%), Gaps = 5/186 (2%)

Query: 67  TPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMD 126
           T S +S    R S+ +  E   S   + A  A  ++ +         +   S    +   
Sbjct: 181 TNSESSTVSSRASTATNSES--STTSSGASTATNSESRTTSNGAGTATNSESSTTSSGAS 238

Query: 127 AYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGS 186
             T  ++S+ S   G+       T +S  G+       S    G +T T S SST S G+
Sbjct: 239 TATNSESSTPSSGAGTATNSESSTTSSGAGTATNSE-SSTVSSGISTVTNSESSTPSSGA 297

Query: 187 GAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMETGD 246
             A       + T    ++A    ++ TS  +      + ST S  A    N+E   T  
Sbjct: 298 NTATN--SESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSS 355

Query: 247 GVPVSS 252
           G   ++
Sbjct: 356 GASTAT 361



 Score = 31.6 bits (70), Expect = 6.2
 Identities = 34/124 (27%), Positives = 51/124 (41%), Gaps = 14/124 (11%)

Query: 133 TSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRL 192
           TSSG     S   +S+ +  SS  SI      S    G++T+T S SST S G+  A   
Sbjct: 83  TSSGI----STATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTA--- 135

Query: 193 ADVMAQTHIENHSAPPDVTTYT-SEHSIQVERPQGSTGSRTAPKYGNAELMETGDGVPVS 251
                 T+ ++ +     +T T S+ S        +T S ++     A      +   VS
Sbjct: 136 ------TNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVS 189

Query: 252 SRVS 255
           SR S
Sbjct: 190 SRAS 193


>gi|5174653 ring finger protein 6 [Homo sapiens]
          Length = 685

 Score = 35.8 bits (81), Expect = 0.33
 Identities = 43/223 (19%), Positives = 79/223 (35%), Gaps = 22/223 (9%)

Query: 77  RRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSG 136
           R +  + + R+  ++H          H E    +P+    R         + +P    + 
Sbjct: 139 RTNPNNGEFRFSLEIHVNHENRGFEIHGEDYTDIPLSDSNRDHTANRQQRSTSPVARRTR 198

Query: 137 SEDEGSVQGDSQGTPTS---------SQGSINMEHWISQAIHGS--------TTSTTSSS 179
           S+   +  G S   P +         ++GS +    +   I G+        + +  SS 
Sbjct: 199 SQTSVNFNGSSSNIPRTRLASRGQNPAEGSFSTLGRLRNGIGGAAGIPRANASRTNFSSH 258

Query: 180 STQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNA 239
           + QSGGS    R        H+  + A  +VT   +   ++  R + ++ SR+       
Sbjct: 259 TNQSGGSELRQREGQRFGAAHVWENGARSNVTVRNTNQRLEPIRLRSTSNSRSRSPIQR- 317

Query: 240 ELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFE 282
              ++G     S R S  +QQ      R +R   R F   D E
Sbjct: 318 ---QSGTVYHNSQRESRPVQQTTRRSVR-RRGRTRVFLEQDRE 356


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 35.8 bits (81), Expect = 0.33
 Identities = 41/177 (23%), Positives = 68/177 (38%), Gaps = 5/177 (2%)

Query: 91   VHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPD-TSSGSEDEGSVQGDSQG 149
            VHT  V  A A       +V  PS        T +   T    T++ S   G+       
Sbjct: 5032 VHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTT 5091

Query: 150  TPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPD 209
            TP S+  +I+      +  H ST  TT+++ T++  S A    +  +  T I        
Sbjct: 5092 TPMSTMSTIHTSS-TPETTHTSTVLTTTATMTRATNSTATP--SSTLGTTRILTELTTTA 5148

Query: 210  VTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMETGDGVPVSSRV-SAKIQQLVNTL 265
             TT  +  +  +    G+T   T P      ++ TG     SS + +A   ++V T+
Sbjct: 5149 TTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTM 5205



 Score = 31.2 bits (69), Expect = 8.2
 Identities = 40/156 (25%), Positives = 59/156 (37%), Gaps = 26/156 (16%)

Query: 92   HTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTP------PDTSSGSEDEGSVQG 145
            HT  V  A A       +V  PS        T +   T       P +S G+     V  
Sbjct: 2711 HTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWI 2770

Query: 146  DSQGTPTSSQGSINMEHWISQAIHGSTTSTTS------------SSSTQSGGSGAAHRLA 193
             +  TPT+ +GS      I    H +T  TT+            SSSTQ+ G+     + 
Sbjct: 2771 STTTTPTT-RGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVP 2829

Query: 194  DVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTG 229
            + MA TH    S PP     +S H+++      ++G
Sbjct: 2830 NTMATTH--GRSLPP-----SSPHTVRTAWTSATSG 2858


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 35.8 bits (81), Expect = 0.33
 Identities = 34/154 (22%), Positives = 60/154 (38%), Gaps = 26/154 (16%)

Query: 32  TQKGYEKKRSKLIGAYLPQPPRVDQALPQERRAPVTPSSASRYHRRRSSGSRDERYRSDV 91
           +Q+G  + RS+      P  P + +  P             R H R S       YR D 
Sbjct: 634 SQQGQRRHRSRASAMSSPSSPGLGRVAP-------------RGHPRHS------HYRKDT 674

Query: 92  HTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTP 151
           H+  + +++ K       VP P +RR      S+  Y+   +S+ ++  G+++  S G+ 
Sbjct: 675 HSP-LDSSVTKQ------VPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPPSSGSL 727

Query: 152 TSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGG 185
            S          ++ A+H    S  S  +  S G
Sbjct: 728 PSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAG 761


>gi|34305295 ring finger protein 6 [Homo sapiens]
          Length = 685

 Score = 35.8 bits (81), Expect = 0.33
 Identities = 43/223 (19%), Positives = 79/223 (35%), Gaps = 22/223 (9%)

Query: 77  RRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSG 136
           R +  + + R+  ++H          H E    +P+    R         + +P    + 
Sbjct: 139 RTNPNNGEFRFSLEIHVNHENRGFEIHGEDYTDIPLSDSNRDHTANRQQRSTSPVARRTR 198

Query: 137 SEDEGSVQGDSQGTPTS---------SQGSINMEHWISQAIHGS--------TTSTTSSS 179
           S+   +  G S   P +         ++GS +    +   I G+        + +  SS 
Sbjct: 199 SQTSVNFNGSSSNIPRTRLASRGQNPAEGSFSTLGRLRNGIGGAAGIPRANASRTNFSSH 258

Query: 180 STQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNA 239
           + QSGGS    R        H+  + A  +VT   +   ++  R + ++ SR+       
Sbjct: 259 TNQSGGSELRQREGQRFGAAHVWENGARSNVTVRNTNQRLEPIRLRSTSNSRSRSPIQR- 317

Query: 240 ELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFE 282
              ++G     S R S  +QQ      R +R   R F   D E
Sbjct: 318 ---QSGTVYHNSQRESRPVQQTTRRSVR-RRGRTRVFLEQDRE 356


>gi|34305293 ring finger protein 6 [Homo sapiens]
          Length = 685

 Score = 35.8 bits (81), Expect = 0.33
 Identities = 43/223 (19%), Positives = 79/223 (35%), Gaps = 22/223 (9%)

Query: 77  RRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSG 136
           R +  + + R+  ++H          H E    +P+    R         + +P    + 
Sbjct: 139 RTNPNNGEFRFSLEIHVNHENRGFEIHGEDYTDIPLSDSNRDHTANRQQRSTSPVARRTR 198

Query: 137 SEDEGSVQGDSQGTPTS---------SQGSINMEHWISQAIHGS--------TTSTTSSS 179
           S+   +  G S   P +         ++GS +    +   I G+        + +  SS 
Sbjct: 199 SQTSVNFNGSSSNIPRTRLASRGQNPAEGSFSTLGRLRNGIGGAAGIPRANASRTNFSSH 258

Query: 180 STQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNA 239
           + QSGGS    R        H+  + A  +VT   +   ++  R + ++ SR+       
Sbjct: 259 TNQSGGSELRQREGQRFGAAHVWENGARSNVTVRNTNQRLEPIRLRSTSNSRSRSPIQR- 317

Query: 240 ELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFE 282
              ++G     S R S  +QQ      R +R   R F   D E
Sbjct: 318 ---QSGTVYHNSQRESRPVQQTTRRSVR-RRGRTRVFLEQDRE 356


>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
          Length = 1458

 Score = 35.8 bits (81), Expect = 0.33
 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 8/102 (7%)

Query: 136 GSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADV 195
           GS+  G   G   G    + G  +  H+IS     S T   S  + ++GGSG A    D 
Sbjct: 13  GSKSPGPGPGPGAGAEPGATGGSS--HFISSRTRSSKTRAASCPAAKAGGSGGAGVTLDE 70

Query: 196 MAQTHI-----ENHSAPPDVTTYTSEHSIQVERPQG-STGSR 231
             +  +     ++H +PP   T     S+  ++ +  STG R
Sbjct: 71  ARKVEVDGSLSDSHVSPPAKRTLKQPDSVCKDKSKSRSTGQR 112


>gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo
           sapiens]
          Length = 386

 Score = 35.4 bits (80), Expect = 0.43
 Identities = 43/178 (24%), Positives = 67/178 (37%), Gaps = 23/178 (12%)

Query: 165 SQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERP 224
           S A+H  T   T S    S GS  +H  +DV ++  +  H   PD+ T+           
Sbjct: 148 SHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTF-------YPLS 200

Query: 225 QGSTGSRTAPKYGNAELMETG------DGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFV 278
            G  G  T P    +  M  G       G+P  + V+ +++Q     + P          
Sbjct: 201 PGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQVKQ-----EHPHTDSDLMHVK 255

Query: 279 DDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAAL-----QRWGTIS 331
              E+  E +   P+  KP  A ML M+  +  VV        AA+     +RW  +S
Sbjct: 256 PQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALS 313


>gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo
           sapiens]
          Length = 371

 Score = 35.4 bits (80), Expect = 0.43
 Identities = 43/178 (24%), Positives = 67/178 (37%), Gaps = 23/178 (12%)

Query: 165 SQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERP 224
           S A+H  T   T S    S GS  +H  +DV ++  +  H   PD+ T+           
Sbjct: 148 SHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTF-------YPLS 200

Query: 225 QGSTGSRTAPKYGNAELMETG------DGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFV 278
            G  G  T P    +  M  G       G+P  + V+ +++Q     + P          
Sbjct: 201 PGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQVKQ-----EHPHTDSDLMHVK 255

Query: 279 DDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAAL-----QRWGTIS 331
              E+  E +   P+  KP  A ML M+  +  VV        AA+     +RW  +S
Sbjct: 256 PQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALS 313


>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
           sapiens]
          Length = 955

 Score = 35.4 bits (80), Expect = 0.43
 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 19/159 (11%)

Query: 29  GDITQKGYEKKRSKLIG---AYLPQPPRVDQALPQERRAPVTPSSASRYHRRRSSGSRDE 85
           G   + GY   RS       AY P+  R     P+ R    +PS  SR H R S  S  +
Sbjct: 97  GQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRR----SPSPRSRSHSRNSDKSSSD 152

Query: 86  RYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSE--DEGSV 143
           R R      +   + + H   +      SKR+S   + S    + P  ++G    DE   
Sbjct: 153 RSR----RSSSSRSSSNHSRVE-----SSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKE 203

Query: 144 QGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQ 182
           Q  S GT   ++ S + + W   A +G+ +++ +S+ ++
Sbjct: 204 QTFSGGTSQDTKASESSKPW-PDATYGTGSASRASAVSE 241


>gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens]
          Length = 967

 Score = 35.0 bits (79), Expect = 0.57
 Identities = 38/164 (23%), Positives = 60/164 (36%), Gaps = 22/164 (13%)

Query: 118 SLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTS 177
           S +  T + +++PP  +S S         +  TP+ S    +     ++    ST S TS
Sbjct: 23  SSIATTEITSHSPPSFTSSST--------TTETPSHSTPGFSSSIATTETTSHSTASFTS 74

Query: 178 SSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQ--------GSTG 229
           S +T    S         +A T I +HS P   ++ T+  +     P         GST 
Sbjct: 75  SIATTETMSQNIPGFTSSIATTEITSHSTPSFTSSITTTETTSQSSPSFTSLITITGSTS 134

Query: 230 SRTAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPL 273
             TA    +    ET      +S  +  I   + T KR     L
Sbjct: 135 HSTASFTSSITTTET------TSHSTRSITSSITTTKRTSHSSL 172



 Score = 32.3 bits (72), Expect = 3.7
 Identities = 44/188 (23%), Positives = 74/188 (39%), Gaps = 24/188 (12%)

Query: 51  PPRVDQALPQERRAPVTPSSASRYHRRRSSGSRDERY-------RSDVH-TEAVQAALAK 102
           P     +   E  +  TP  +S     +++ +   R+       ++ +H T     A+A 
Sbjct: 549 PSFTSSSTTTETHSHSTPGFSSSIATSKTTSTSPPRFTFAIATTKTTLHSTPRFTLAIAS 608

Query: 103 HKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEH 162
            K    + P  +   SL+      ++  P  +S     G++   S  TP     S     
Sbjct: 609 TKTTSHSTPSLT---SLITTIETTSHCTPSLTSSITTSGTI---SHSTP-----SFTSLI 657

Query: 163 WISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVE 222
            I+++   STTS  SS +T    S +      ++A T I +HS P    +YTS  +   E
Sbjct: 658 TITESTSHSTTSFPSSITTTETTSHSTPSFTSLIATTEIISHSTP----SYTSSIA-TTE 712

Query: 223 RPQGSTGS 230
            P  ST S
Sbjct: 713 TPSHSTPS 720



 Score = 32.0 bits (71), Expect = 4.8
 Identities = 45/191 (23%), Positives = 70/191 (36%), Gaps = 40/191 (20%)

Query: 111 PMPSKRRSLVVQTSMDAYTPPD-TSSGSEDE-------------GSVQGDSQGTP----- 151
           P P +  SL+  T   +++PP  T+S +  E              S +  SQ TP     
Sbjct: 767 PFPPRFTSLITTTKTTSHSPPSFTASLTSTEATSHSPLSFTSVIASTKITSQSTPSLTSL 826

Query: 152 -----TSSQGSINMEHWI--SQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENH 204
                TSS  ++ +   +  ++    ST S TS  +T    S         +A T I +H
Sbjct: 827 ITTTGTSSHNTLGLSSSVDTTKTTSHSTASFTSLIATTETTSHNTPGFTSSIATTEITSH 886

Query: 205 SAPPDVTTYTSEHSIQVERPQ--------GSTGSRTAPKYGNAELMETGDGVPVSSRVSA 256
           S P   ++ T+  +     P         GST   TA    +    ET      +S  + 
Sbjct: 887 STPSFTSSITTMETTSRSSPSFTSLITITGSTSHSTASFTSSITTTET------TSHSTP 940

Query: 257 KIQQLVNTLKR 267
            I   V T +R
Sbjct: 941 SITSSVTTAER 951


>gi|38202211 N-acetylglucosamine-1-phosphate transferase [Homo
           sapiens]
          Length = 1256

 Score = 35.0 bits (79), Expect = 0.57
 Identities = 16/38 (42%), Positives = 24/38 (63%)

Query: 11  LPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYL 48
           LP + +  L  L+L+L  GDIT KGY   +S L+ ++L
Sbjct: 703 LPKDAQLSLNTLDLQLEHGDITLKGYNLSKSALLRSFL 740


>gi|63055059 SH3 and PX domains 2B [Homo sapiens]
          Length = 911

 Score = 34.7 bits (78), Expect = 0.74
 Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 2/93 (2%)

Query: 27  SEGDITQKGYEKKRSKLIGAYLPQPPRVDQALPQERRAPVTPSSASRYHRRRSSGSRDER 86
           SEG++ ++  E++R++ +    P+PP V   LP      + P+  SR    +   SR  +
Sbjct: 532 SEGELLERERERQRTEQLRGPTPKPPGV--ILPMMPAKHIPPARDSRRPEPKPDKSRLFQ 589

Query: 87  YRSDVHTEAVQAALAKHKERKMAVPMPSKRRSL 119
            ++D+  E     LAK  ++    P+   +  L
Sbjct: 590 LKNDMGLECGHKVLAKEVKKPNLRPISKSKTDL 622


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 34.3 bits (77), Expect = 0.96
 Identities = 47/227 (20%), Positives = 85/227 (37%), Gaps = 18/227 (7%)

Query: 18   RLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQALPQERRA------PVTPSSA 71
            RL   +++  E     +  E+KR +        P   D+  P++ +       P T    
Sbjct: 889  RLPSFKVKRKEPSEISEASEEKRPRP-----STPAEEDEDDPEQEKEAGEPGRPGTKPPK 943

Query: 72   SRYHRRRSSGSRDERYRSDVH-TEAVQAALAKHKERKMAVPMPSKRRSLVVQTSM---DA 127
                R ++ G   + +  D    EA Q + ++  E         + R   V T+    + 
Sbjct: 944  RDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEV 1003

Query: 128  YTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSG 187
                D  S S  + S+  DS G   S+  S   E   S +   S++S++SSSS+ S    
Sbjct: 1004 SDGEDEESDSSSKCSLYADSDGENDSTSDS---ESSSSSSSSSSSSSSSSSSSSSSSSES 1060

Query: 188  AAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAP 234
            ++    +      + + S PP      +   ++V  P+   GS   P
Sbjct: 1061 SSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTP 1107


>gi|27477105 lipidosin [Homo sapiens]
          Length = 724

 Score = 34.3 bits (77), Expect = 0.96
 Identities = 35/128 (27%), Positives = 52/128 (40%), Gaps = 28/128 (21%)

Query: 1337 SPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNASGYFTIYGDESLQS 1396
            SP++  L  SGK++PG R+ + N + +G      +GEI +       GY  +        
Sbjct: 487  SPYNYRLYSSGKLVPGCRVKLVNQDAEG------IGEICLWGRTIFMGYLNMEDKTCEAI 540

Query: 1397 DHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDE-AMELRGMRYH 1455
            D           +  W  TG  G L      DA+G     LY+ G L E  +   G    
Sbjct: 541  D-----------EEGWLHTGDAGRL------DADG----FLYITGRLKELIITAGGENVP 579

Query: 1456 PIDIETSV 1463
            P+ IE +V
Sbjct: 580  PVPIEEAV 587


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 34.3 bits (77), Expect = 0.96
 Identities = 47/211 (22%), Positives = 84/211 (39%), Gaps = 54/211 (25%)

Query: 34  KGYEKKRSKLIGAYLPQPPRVDQALPQERRAPVTPSSASRYHRRRSSGSRDERYRSDVHT 93
           KG +++      +   +PP  D+   +E++AP TP    R  R+ SS   D    SD+ +
Sbjct: 299 KGVDEQSDSSEESEEEKPPEEDKEEEEEKKAP-TPQEKKR--RKDSSEESDSSEESDIDS 355

Query: 94  EAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQ-GTPT 152
           EA  A     K+                       TPP         GS +G+S+ GTP+
Sbjct: 356 EASSALFMAKKK-----------------------TPPKRER-KPSGGSSRGNSRPGTPS 391

Query: 153 SSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTT 212
           +  GS             S+T   ++S  + G      R++++ A   +   + P  ++ 
Sbjct: 392 AEGGST------------SSTLRAAASKLEQG-----KRVSEMPAAKRLRLDTGPQSLSG 434

Query: 213 YTSEHSIQVERPQGSTGSRTAPKYGNAELME 243
            ++        PQ  +G +T P  G+ ++ E
Sbjct: 435 KST--------PQPPSG-KTTPNSGDVQVTE 456


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,105,597
Number of Sequences: 37866
Number of extensions: 2910509
Number of successful extensions: 8136
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 7827
Number of HSP's gapped (non-prelim): 251
length of query: 1556
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1440
effective length of database: 13,855,062
effective search space: 19951289280
effective search space used: 19951289280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.