Search of human proteins with 44680122

Search of human proteins with 44680122

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|44680122 tripartite motif-containing 7 isoform 1 [Homo
sapiens]
         (511 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]   1031   0.0  
gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]    613   e-175
gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]    609   e-174
gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]    609   e-174
gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]    609   e-174
gi|16076875 tripartite motif-containing 7 isoform 4 [Homo sapiens]    423   e-118
gi|5730009 ret finger protein [Homo sapiens]                          330   1e-90
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   323   2e-88
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   309   4e-84
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            293   3e-79
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             290   2e-78
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...   280   3e-75
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]   266   4e-71
gi|15208660 tripartite motif protein 21 [Homo sapiens]                257   2e-68
gi|149193331 tripartite motif protein 15 [Homo sapiens]               255   8e-68
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   248   9e-66
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   246   5e-65
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    246   5e-65
gi|37622899 ring finger protein 137 [Homo sapiens]                    243   2e-64
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...   237   2e-62
gi|4508005 tripartite motif-containing 26 [Homo sapiens]              235   6e-62
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            229   4e-60
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              227   2e-59
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...   227   2e-59
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]   213   3e-55
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             212   7e-55
gi|22749269 ring finger protein 129 [Homo sapiens]                    211   2e-54
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]   206   3e-53
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    206   4e-53
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    206   4e-53

>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score = 1031 bits (2667), Expect = 0.0
 Identities = 511/511 (100%), Positives = 511/511 (100%)

Query: 1   MAAVGPRTGPGTGAEALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERP 60
           MAAVGPRTGPGTGAEALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERP
Sbjct: 1   MAAVGPRTGPGTGAEALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERP 60

Query: 61  GAGSVGAATRAPPFPLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQA 120
           GAGSVGAATRAPPFPLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQA
Sbjct: 61  GAGSVGAATRAPPFPLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQA 120

Query: 121 AAARAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESR 180
           AAARAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESR
Sbjct: 121 AAARAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESR 180

Query: 181 LRVLKKELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEE 240
           LRVLKKELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEE
Sbjct: 181 LRVLKKELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEE 240

Query: 241 LSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKP 300
           LSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKP
Sbjct: 241 LSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKP 300

Query: 301 TTVSSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLD 360
           TTVSSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLD
Sbjct: 301 TTVSSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLD 360

Query: 361 LKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRR 420
           LKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRR
Sbjct: 361 LKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRR 420

Query: 421 KGLTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDM 480
           KGLTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDM
Sbjct: 421 KGLTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDM 480

Query: 481 RHLYTFRVNFQERVFPLFSVCSTGTYLRIWP 511
           RHLYTFRVNFQERVFPLFSVCSTGTYLRIWP
Sbjct: 481 RHLYTFRVNFQERVFPLFSVCSTGTYLRIWP 511


>gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]
          Length = 329

 Score =  613 bits (1581), Expect = e-175
 Identities = 305/305 (100%), Positives = 305/305 (100%)

Query: 207 KQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKL 266
           KQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKL
Sbjct: 25  KQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKL 84

Query: 267 SSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLK 326
           SSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLK
Sbjct: 85  SSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLK 144

Query: 327 KFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRV 386
           KFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRV
Sbjct: 145 KFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRV 204

Query: 387 LASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVT 446
           LASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVT
Sbjct: 205 LASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVT 264

Query: 447 SPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTY 506
           SPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTY
Sbjct: 265 SPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTY 324

Query: 507 LRIWP 511
           LRIWP
Sbjct: 325 LRIWP 329


>gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  609 bits (1571), Expect = e-174
 Identities = 303/303 (100%), Positives = 303/303 (100%)

Query: 209 MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS 268
           MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS
Sbjct: 1   MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS 60

Query: 269 QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF 328
           QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF
Sbjct: 61  QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF 120

Query: 329 KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA 388
           KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA
Sbjct: 121 KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA 180

Query: 389 SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP 448
           SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP
Sbjct: 181 SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP 240

Query: 449 ERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLR 508
           ERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLR
Sbjct: 241 ERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLR 300

Query: 509 IWP 511
           IWP
Sbjct: 301 IWP 303


>gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  609 bits (1571), Expect = e-174
 Identities = 303/303 (100%), Positives = 303/303 (100%)

Query: 209 MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS 268
           MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS
Sbjct: 1   MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS 60

Query: 269 QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF 328
           QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF
Sbjct: 61  QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF 120

Query: 329 KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA 388
           KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA
Sbjct: 121 KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA 180

Query: 389 SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP 448
           SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP
Sbjct: 181 SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP 240

Query: 449 ERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLR 508
           ERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLR
Sbjct: 241 ERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLR 300

Query: 509 IWP 511
           IWP
Sbjct: 301 IWP 303


>gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  609 bits (1571), Expect = e-174
 Identities = 303/303 (100%), Positives = 303/303 (100%)

Query: 209 MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS 268
           MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS
Sbjct: 1   MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS 60

Query: 269 QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF 328
           QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF
Sbjct: 61  QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF 120

Query: 329 KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA 388
           KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA
Sbjct: 121 KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA 180

Query: 389 SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP 448
           SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP
Sbjct: 181 SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP 240

Query: 449 ERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLR 508
           ERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLR
Sbjct: 241 ERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYLR 300

Query: 509 IWP 511
           IWP
Sbjct: 301 IWP 303


>gi|16076875 tripartite motif-containing 7 isoform 4 [Homo sapiens]
          Length = 221

 Score =  423 bits (1088), Expect = e-118
 Identities = 207/210 (98%), Positives = 207/210 (98%)

Query: 1   MAAVGPRTGPGTGAEALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERP 60
           MAAVGPRTGPGTGAEALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERP
Sbjct: 1   MAAVGPRTGPGTGAEALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERP 60

Query: 61  GAGSVGAATRAPPFPLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQA 120
           GAGSVGAATRAPPFPLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQA
Sbjct: 61  GAGSVGAATRAPPFPLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQA 120

Query: 121 AAARAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESR 180
           AAARAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESR
Sbjct: 121 AAARAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESR 180

Query: 181 LRVLKKELEDCEVFRSTEKKESKELLKQMA 210
           LRVLKKELEDCEVFRSTEKKESKELL   A
Sbjct: 181 LRVLKKELEDCEVFRSTEKKESKELLVSQA 210


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  330 bits (847), Expect = 1e-90
 Identities = 199/500 (39%), Positives = 280/500 (56%), Gaps = 37/500 (7%)

Query: 18  ALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLP 77
           ++A  LQ E TC +CL+ F EP+ ++CGH+ C AC+ RCW   G      +         
Sbjct: 5   SVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCW---GTAETNVS--------- 52

Query: 78  CPQCREPARPSQLRPNRQLAAVATLLR--RFSLPAAAPGEHGSQAAAARAAAARCGQHGE 135
           CPQCRE      +RPNR LA V  L++  R   P+   GE G            C +H E
Sbjct: 53  CPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGV-----------CEKHRE 101

Query: 136 PFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFR 195
           P KLYC++D   ICVVCDR+REHR H+VLPL+EAV+  KE ++++L  LK+ ++D +  R
Sbjct: 102 PLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKR-VKDLKKRR 160

Query: 196 STEKKESK-ELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLA 254
             + ++++ ELL     E+EK+  EF+ L   L E E RLL RLEEL   +    N  + 
Sbjct: 161 RAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAIT 220

Query: 255 QLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNV 314
           Q    I+ LS L +Q++E  Q+P  + LQ+   TLSR   +  P+P     +++ K+   
Sbjct: 221 QFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIF 280

Query: 315 SLKTFVLKGMLKKFKEDLRGELEKEEK--------VELTLDPDTANPRLILSLDLKGVRL 366
           + K   L   LK+F E ++ ++EK ++        V++TLDPDTA P LILS +L+ VR 
Sbjct: 281 AQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRY 340

Query: 367 GERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPF 426
               QDLP++P RF+    VL S  F +GRH+WEVEVG K  W  GV  +SV RKG    
Sbjct: 341 SYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTS 400

Query: 427 TPEEGVWALQL-NGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYT 485
            P+ G WA+ L  G +YWA+TSP  +      L RV + LD + G VSFY V +  H +T
Sbjct: 401 APQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFT 460

Query: 486 F-RVNFQERVFPLFSVCSTG 504
           F    F   V P FS+  +G
Sbjct: 461 FSHATFCGPVRPYFSLSYSG 480


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  323 bits (828), Expect = 2e-88
 Identities = 192/496 (38%), Positives = 283/496 (57%), Gaps = 48/496 (9%)

Query: 11  GTGAEALALAAE-LQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAAT 69
           G  A + A A E LQ EA+CS+CLE  +EPV +ECGH+FC+ACI R WE           
Sbjct: 10  GASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERD------ 63

Query: 70  RAPPFPLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAA-AA 128
                  PCP CR+ +R   LRPNRQL ++  + ++             QA   +    +
Sbjct: 64  ------FPCPVCRKTSRYRSLRPNRQLGSMVEIAKQL------------QAVKRKIRDES 105

Query: 129 RCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKEL 188
            C QH E   L+C +D  A+C++C  +  HR H V+PLD+A QE KE L+  L  L+++L
Sbjct: 106 LCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKL 165

Query: 189 EDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQK 248
           ++    +S+E+K+  EL + + + ++++  EF+ L   L E++  LL RLEE  +++ Q+
Sbjct: 166 QEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQR 225

Query: 249 QNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMK 308
             EN A LG +   L+ L+++++    +   + L++ KSTL +C  V   + T+VS E++
Sbjct: 226 LRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELE 285

Query: 309 NKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGE 368
               N   + F L+ +LK+   D            +TLDP+TA+P L+LS D K V+  E
Sbjct: 286 KNFSNFPRQYFALRKILKQLIAD------------VTLDPETAHPNLVLSEDRKSVKFVE 333

Query: 369 -RAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKG-LTPF 426
            R +DLP+ P RF     VLA+ GF+SGRH+WEVEVG K  WA GV R+SV RKG LTP 
Sbjct: 334 TRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPL 393

Query: 427 TPEEGVWALQLNGGQYWAVTSPERSPLSCGHL----SRVRVALDLEVGAVSFYAVEDMRH 482
            PE G W ++L  G  +A T+   +PL   H+     RV + LD E G +SFY V D  H
Sbjct: 394 -PETGYWRVRLWNGDKYAATTTPFTPL---HIKVKPKRVGIFLDYEAGTLSFYNVTDRSH 449

Query: 483 LYTFRVNFQERVFPLF 498
           +YTF   F E+++PLF
Sbjct: 450 IYTFTDTFTEKLWPLF 465


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  309 bits (791), Expect = 4e-84
 Identities = 193/526 (36%), Positives = 284/526 (53%), Gaps = 78/526 (14%)

Query: 11  GTGAEALALAAE-LQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAAT 69
           G  A + A A E LQ EA+CS+CLE  +EPV +ECGH+FC+ACI R WE           
Sbjct: 10  GASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERD------ 63

Query: 70  RAPPFPLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAA-AA 128
                  PCP CR+ +R   LRPNRQL ++  + ++             QA   +    +
Sbjct: 64  ------FPCPVCRKTSRYRSLRPNRQLGSMVEIAKQL------------QAVKRKIRDES 105

Query: 129 RCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKEL 188
            C QH E   L+C +D  A+C++C  +  HR H V+PLD+A QE KE L+  L  L+++L
Sbjct: 106 LCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKL 165

Query: 189 EDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQK 248
           ++    +S+E+K+  EL + + + ++++  EF+ L   L E++  LL RLEE  +++ Q+
Sbjct: 166 QEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQR 225

Query: 249 QNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTL------------------- 289
             EN A LG +   L+ L+++++    +   + L++ KSTL                   
Sbjct: 226 LRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRD 285

Query: 290 -----------SRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEK 338
                      +RC  V   + T+VS E++    N   + F L+ +LK+   D+      
Sbjct: 286 HKALLGLVKEINRCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADV------ 339

Query: 339 EEKVELTLDPDTANPRLILSLDLKGVRLGE-RAQDLPNHPCRFDTNTRVLASCGFSSGRH 397
                 TLDP+TA+P L+LS D K V+  E R +DLP+ P RF     VLA+ GF+SGRH
Sbjct: 340 ------TLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRH 393

Query: 398 HWEVEVGSKDGWAFGVARESVRRKG-LTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCG 456
           +WEVEVG K  WA GV R+SV RKG LTP  PE G W ++L  G  +A T+   +PL   
Sbjct: 394 YWEVEVGDKTHWAVGVCRDSVSRKGELTPL-PETGYWRVRLWNGDKYAATTTPFTPL--- 449

Query: 457 HL----SRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLF 498
           H+     RV + LD E G +SFY V D  H+YTF   F E+++PLF
Sbjct: 450 HIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLF 495


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  293 bits (749), Expect = 3e-79
 Identities = 174/480 (36%), Positives = 251/480 (52%), Gaps = 39/480 (8%)

Query: 23  LQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCR 82
           L+ +A C +CL+  +EPVSV+CGHSFC  CI    E+      G           CPQCR
Sbjct: 10  LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYA--------CPQCR 61

Query: 83  EPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQ 142
            P RPS  RPNRQLA +   +RR  L  A PG            A RC +HGE    +C+
Sbjct: 62  GPFRPSGFRPNRQLAGLVESVRRLGL-GAGPG------------ARRCARHGEDLSRFCE 108

Query: 143 DDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKES 202
           +D  A+C VCD   EHR H   PL EA    +  L+  L +++KELED     +   K++
Sbjct: 109 EDEAALCWVCDAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKT 168

Query: 203 KELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQ 262
               +++  ++++   EF+  R FL ++E R L RLE   R   Q+  E+ ++L  +   
Sbjct: 169 VIWKEKVEMQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKA 228

Query: 263 LSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLK 322
           L +L+ ++QE  Q+P L  L+  +  LSR   V   +   +  E+K            + 
Sbjct: 229 LKELADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKT--------ACCIP 280

Query: 323 GMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDT 382
           G         R EL ++ +V++ LDP TA+P L+L+ DL+ V+ GE  +D+PN+P RFDT
Sbjct: 281 G---------RRELLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDT 331

Query: 383 NTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWAL-QLNGGQ 441
              +L    FSSGRH+WEV VG    W  GV ++++ RKG T  +PE GVWAL  L G +
Sbjct: 332 WPCILGLQSFSSGRHYWEVLVGEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNE 391

Query: 442 YWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVC 501
           Y  + SP    L       + + LD E G +SFY V D  ++YTF   F   + P F +C
Sbjct: 392 YMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFIC 451


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  290 bits (743), Expect = 2e-78
 Identities = 178/489 (36%), Positives = 249/489 (50%), Gaps = 51/489 (10%)

Query: 19  LAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPC 78
           L+  LQ EATC+ICL+ F +PV  +CGH+FCR CI RCW +P              P  C
Sbjct: 6   LSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEG------------PYAC 53

Query: 79  PQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFK 138
           P+CRE +    LRPNR LA +A + RR   P+  P                C  H EP  
Sbjct: 54  PECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVP-------------QGVCPAHREPLA 100

Query: 139 LYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTE 198
            +C D+ R +C  C+R+ EH  H V PL +A ++ K  LE  L  L+K+++D  +F++  
Sbjct: 101 AFCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQA 160

Query: 199 KKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGV 258
            +      K + ++++ V  EF+ LR  L E+E +LL RLEE   EV  +  E  A LG 
Sbjct: 161 DETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQ 220

Query: 259 EITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKT 318
           +   L++L ++++   Q P L  LQ+ K  L R  +V    P  V  E++        + 
Sbjct: 221 QSAHLAELIAELEGRCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELR-----TVCRV 275

Query: 319 FVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPC 378
             L   L++F+ D            +TLDPDTANP LILS D + V+ G+  Q LP+ P 
Sbjct: 276 PGLVETLRRFRGD------------VTLDPDTANPELILSEDRRSVQRGDLRQALPDSPE 323

Query: 379 RFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLN 438
           RFD    VL    F+SGRH+WEVEVG +  WA GV RE+V RK     +   G W L   
Sbjct: 324 RFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEKGELSAGNGFWILVFL 383

Query: 439 GGQYWA---VTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTF-RVNFQERV 494
           G  Y +     +P R P       RV + LD E G +SFY+  D   L+ F  + F   +
Sbjct: 384 GSYYNSSERALAPLRDP-----PRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTL 438

Query: 495 FPLFSVCST 503
            PLFS  S+
Sbjct: 439 RPLFSPLSS 447


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score =  280 bits (715), Expect = 3e-75
 Identities = 174/492 (35%), Positives = 258/492 (52%), Gaps = 25/492 (5%)

Query: 18  ALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLP 77
           A    L  E  C IC    REPV+++CGH+FCRAC+ R  E PG     + T        
Sbjct: 5   ASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPT-------- 56

Query: 78  CPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAP-GEHGSQAAAARAAAARCGQHGEP 136
           CP C+EP RP   RPN QLA V   + R  L +    GE              C +HGE 
Sbjct: 57  CPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDV-----------CQEHGEK 105

Query: 137 FKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRS 196
              +C+DD   +CVVC  A EH  H +  L++A    +E +   L+ L+KE E+ +  +S
Sbjct: 106 IYFFCEDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQS 165

Query: 197 TEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQL 256
            E K  + LL Q++ ++++V +EF  LR FL EQ+  LL +LE    ++ ++++E    +
Sbjct: 166 RENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLV 225

Query: 257 GVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSL 316
             EI + S L  +++E  ++P  + L + +STL RC      KP  VS E+  ++ +   
Sbjct: 226 AGEICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQ 285

Query: 317 KTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNH 376
           +   L+  +K F E L  EL+  E   ++LDP T++P+L+LS D +  +   + Q+ P++
Sbjct: 286 QALPLQREMKMFLEKLCFELD-YEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDN 344

Query: 377 PCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWA--FGVARESVRRKGLTPFTPEEGVWA 434
           P RFD  T VLA  G + GRH W V +    G +   GV  E V+RKG     PEEGVWA
Sbjct: 345 PQRFDRATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWA 404

Query: 435 LQLNGGQYWAVTS-PERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQER 493
           ++L  G   A+ S P R  L      +VRV+LD EVG V+F        +YTF  +F  +
Sbjct: 405 VRLAWGFVSALGSFPTRLTLK-EQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRK 463

Query: 494 VFPLFSVCSTGT 505
           V P F +   G+
Sbjct: 464 VIPFFGLWGRGS 475


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score =  266 bits (679), Expect = 4e-71
 Identities = 174/478 (36%), Positives = 245/478 (51%), Gaps = 51/478 (10%)

Query: 69  TRAPPFPLP-----CPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAA 123
           T  PP P P     CPQCR+       RPN QLA +  ++R+       PG  GS+    
Sbjct: 169 TPLPPPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMH---PTPGR-GSRVTDQ 224

Query: 124 RAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRV 183
                 C +H E  KL+C+ D  AICVVC  +R H++H+V+PL+E VQE K  L+  +  
Sbjct: 225 GI----CPKHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEP 280

Query: 184 LKKELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSR 243
           L+K LE  +  ++ E++   EL  QM +E   V +EF  L  FL E++  L  RL E+  
Sbjct: 281 LRKHLEAVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHE 340

Query: 244 EVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTV 303
               +     ++L  +  QLS+L ++ QE +Q+  L  LQ+ K T +RC  V    P   
Sbjct: 341 AQLGRAGAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVW 400

Query: 304 SSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKG 363
           S +      +  L   +++ M + F +  R        V+LTLDPDTA+P L+LS D +G
Sbjct: 401 SPDPCQPHSHDFLTDAIVRKMSRMFCQAAR--------VDLTLDPDTAHPALMLSPDRRG 452

Query: 364 VRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESV----- 418
           VRL ER Q++ +HP RF  +  VL + GF SGRH+WEVEVG + GWA G ARES      
Sbjct: 453 VRLAERRQEVADHPKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEK 512

Query: 419 ---------------------RRKGLTPFTP--EEGVWALQLNGGQYWAVTSPERSPLSC 455
                                RR+   P  P  +  VW +  NG +Y A +S E++ LS 
Sbjct: 513 VGPGGSSVGSGDASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSP 572

Query: 456 GHLSR-VRVALDLEVGAVSFYAVEDMRHLYTFRVNF-QERVFPLFSVCSTGTYLRIWP 511
               R   V LD E G + FY  E + H++TF   F  ERVFP F V S GT +++ P
Sbjct: 573 SEKPRRFGVYLDYEAGRLGFYNAETLAHVHTFSAAFLGERVFPFFRVLSKGTRIKLCP 630



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 20/35 (57%), Positives = 27/35 (77%)

Query: 23 LQGEATCSICLELFREPVSVECGHSFCRACIGRCW 57
          LQ EA C+ICL+ F +PVS+ CGH+FCR C+ + W
Sbjct: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  257 bits (656), Expect = 2e-68
 Identities = 180/481 (37%), Positives = 248/481 (51%), Gaps = 53/481 (11%)

Query: 26  EATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREPA 85
           E TC ICL+ F EPVS+ECGHSFC+ CI +  +  G GSV            CP CR+  
Sbjct: 13  EVTCPICLDPFVEPVSIECGHSFCQECISQVGK--GGGSV------------CPVCRQRF 58

Query: 86  RPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQDDG 145
               LRPNRQLA +   L+  S           Q A       RC  HGE   L+C+ DG
Sbjct: 59  LLKNLRPNRQLANMVNNLKEIS-----------QEAREGTQGERCAVHGERLHLFCEKDG 107

Query: 146 RAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKESKEL 205
           +A+C VC ++R+HR+HA++PL+EA QE +E L+  L  L+++ E  E        +  + 
Sbjct: 108 KALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADW 167

Query: 206 LKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSK 265
            K +  ++ ++ AEF   + FLVE+E R L  LE+  RE  +   E  A+L  +   L +
Sbjct: 168 KKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQE 227

Query: 266 LSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGML 325
           L S++        L+ LQE    L R S     K   ++S     V +V      LK ML
Sbjct: 228 LISELDRRCHSSALELLQEVIIVLER-SESWNLKDLDITSPELRSVCHVP----GLKKML 282

Query: 326 KKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTR 385
           +               V +TLDPDTANP LILS D + VRLG+  Q +P +  RFD+   
Sbjct: 283 RTC------------AVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPM 330

Query: 386 VLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQL-NGGQYWA 444
           VL +  F SG+H+WEV+V  K+ W  GV R+SVRRKG    + + G W + L N  +Y A
Sbjct: 331 VLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEA 390

Query: 445 VTSPERSPLSCGHLS----RVRVALDLEVGAVSFYAVEDMRHL-YTF-RVNFQERVFPLF 498
            T P+ +PL   HL     +V + LD E G VSFY + D   L Y+F    F   + P F
Sbjct: 391 GTYPQ-TPL---HLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFF 446

Query: 499 S 499
           S
Sbjct: 447 S 447


>gi|149193331 tripartite motif protein 15 [Homo sapiens]
          Length = 465

 Score =  255 bits (651), Expect = 8e-68
 Identities = 159/484 (32%), Positives = 249/484 (51%), Gaps = 39/484 (8%)

Query: 29  CSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREPARPS 88
           C++C     + V++ CGH+FCR C+      P    +GA +      L CP C+E     
Sbjct: 16  CTLCAGPLEDAVTIPCGHTFCRLCL------PALSQMGAQSSGKI--LLCPLCQE----- 62

Query: 89  QLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQDDGRAI 148
           + +    +A V         P    GE              C +HGE    +C++D   +
Sbjct: 63  EEQAETPMAPV---------PLGPLGE------------TYCEEHGEKIYFFCENDAEFL 101

Query: 149 CVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKESKELLKQ 208
           CV C     H+ H V  LDEA+Q  ++ L SRL  L  E ++ E  +  E ++ + LL Q
Sbjct: 102 CVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQ 161

Query: 209 MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS 268
           + +++ +V   F+ L+  L +Q   LL RL EL +++ ++++E + ++  E+T+L     
Sbjct: 162 IESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVK 221

Query: 269 QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF 328
           +++E  Q+P  + LQ+ +   SRC       P  +S ++  K+ +   K   L  M++ F
Sbjct: 222 ELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMF 281

Query: 329 KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA 388
            E+L   LE +  V +TLDP TA+  L+LS D K VR   + + LP+ P RFD    VL 
Sbjct: 282 SENLAHHLEIDSGV-ITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLG 340

Query: 389 SCGFSSGRHHWEV--EVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVT 446
             GFSSGRH W+V  ++G   G   GVA E VRRKG    + E+GVWA+ ++  Q WA T
Sbjct: 341 FPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWAST 400

Query: 447 SPERSPLSCGHLSR-VRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGT 505
           SP  + L    + R VRVALD E G V+ +  +    ++TF  +F  +VFP F+V   G+
Sbjct: 401 SP-GTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGS 459

Query: 506 YLRI 509
            L +
Sbjct: 460 CLTL 463


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  248 bits (633), Expect = 9e-66
 Identities = 167/505 (33%), Positives = 247/505 (48%), Gaps = 76/505 (15%)

Query: 20  AAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCP 79
           A ++Q E TC ICL+ F++PVS+ECGH+FCR C+ R W  PG G           P PCP
Sbjct: 3   AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWA-PGGG-----------PFPCP 50

Query: 80  QCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKL 139
           +CR P+ P+ LRPN  LA +    +R  L    PG               CG+H EP +L
Sbjct: 51  ECRHPSAPAALRPNWALARLTEKTQRRRLGPVPPG--------------LCGRHWEPLRL 96

Query: 140 YCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEK 199
           +C+DD R +C+VC  ++EH+ HA+ P+DEA +  +E L    R L  +++     +  E 
Sbjct: 97  FCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEV 156

Query: 200 KESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVE 259
           K + +   ++ +++ ++  EF  L  FLVE+E   L RL +   E  +K NEN  +L   
Sbjct: 157 KNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQT 216

Query: 260 ITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTF 319
           I  L KL  ++ E +Q P L+ LQ  K  L+R             SE+++   N SL+  
Sbjct: 217 IASLKKLILEVGEKSQAPTLELLQNPKEVLTR-------------SEIQDV--NYSLEAV 261

Query: 320 VLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPC- 378
            +K +    +  L  E+ K  +V + L  DTA+P+L+ S + + V+    A   P     
Sbjct: 262 KVKTVC---QIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSA 318

Query: 379 -----------------RFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRK 421
                            RF     VL    F+SG+H+WEVE       A GV RE V   
Sbjct: 319 WNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDV--M 376

Query: 422 GLT---PFTPEEGVWALQLNGGQYWAV-----TSPERSPLSCGHLSRVRVALDLEVGAVS 473
           G+T     +P+ G+WA+  +   YW +     T  ++ P     L RV V LD   G VS
Sbjct: 377 GITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPA----LHRVGVYLDRGTGNVS 432

Query: 474 FYAVEDMRHLYTFRVNFQERVFPLF 498
           FY+  D  HL+TF  +   R+ P F
Sbjct: 433 FYSAVDGVHLHTFSCSSVSRLRPFF 457


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  246 bits (627), Expect = 5e-65
 Identities = 170/491 (34%), Positives = 240/491 (48%), Gaps = 43/491 (8%)

Query: 15  EALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPF 74
           EA+ LA +LQ EATCSICL+ F +PV   CGH+FCRACI   WE+   G  G   R   F
Sbjct: 2   EAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEK-ARGKKGRRKRKGSF 60

Query: 75  PLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHG 134
           P  CP+CRE +    L PNR L  VA + ++       PG               C +H 
Sbjct: 61  P--CPECREMSPQRNLLPNRLLTKVAEMAQQH------PGLQKQDL---------CQEHH 103

Query: 135 EPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVF 194
           EP KL+CQ D   ICVVC  +REHR H VLP +EAVQ  K  LE  +  L++++      
Sbjct: 104 EPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNL 163

Query: 195 RSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLA 254
           ++ E++   E   ++   +E++  EF+ +  +LVE+E RLL  LE    E A +  E++A
Sbjct: 164 QAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVA 223

Query: 255 QLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNV 314
            L  +   L  L  Q++E + +  L  LQ+ K  LSR +NV    P          V  V
Sbjct: 224 CLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRV 283

Query: 315 SLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLP 374
             +  VL+G L+                ++  D  +A P L+L    +   LG   +   
Sbjct: 284 PGQIEVLRGFLE----------------DVVPDATSAYPYLLLYESRQRRYLGSSPEG-- 325

Query: 375 NHPC---RFDTNTRVLASCGFSSGRHHWEV--EVGSKDGWAFGVARESVRRKGLTPFTPE 429
           +  C   RF      +    FSSGRH+WEV   +     WA GV R++V RK   P  PE
Sbjct: 326 SGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPE 385

Query: 430 EGVWALQLNGGQYWAVTSPERSPLSCGH-LSRVRVALDLEVGAVSFYAVEDMRHLYTF-R 487
            G W +QL+ G  +  T    +P+      S + + LD E G VSFY+V D  HL+T+ +
Sbjct: 386 NGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQ 445

Query: 488 VNFQERVFPLF 498
             F   + P F
Sbjct: 446 ATFPGPLQPFF 456


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  246 bits (627), Expect = 5e-65
 Identities = 170/491 (34%), Positives = 240/491 (48%), Gaps = 43/491 (8%)

Query: 15  EALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPF 74
           EA+ LA +LQ EATCSICL+ F +PV   CGH+FCRACI   WE+   G  G   R   F
Sbjct: 2   EAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEK-ARGKKGRRKRKGSF 60

Query: 75  PLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHG 134
           P  CP+CRE +    L PNR L  VA + ++       PG               C +H 
Sbjct: 61  P--CPECREMSPQRNLLPNRLLTKVAEMAQQH------PGLQKQDL---------CQEHH 103

Query: 135 EPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVF 194
           EP KL+CQ D   ICVVC  +REHR H VLP +EAVQ  K  LE  +  L++++      
Sbjct: 104 EPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNL 163

Query: 195 RSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLA 254
           ++ E++   E   ++   +E++  EF+ +  +LVE+E RLL  LE    E A +  E++A
Sbjct: 164 QAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVA 223

Query: 255 QLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNV 314
            L  +   L  L  Q++E + +  L  LQ+ K  LSR +NV    P          V  V
Sbjct: 224 CLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRV 283

Query: 315 SLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLP 374
             +  VL+G L+                ++  D  +A P L+L    +   LG   +   
Sbjct: 284 PGQIEVLRGFLE----------------DVVPDATSAYPYLLLYESRQRRYLGSSPEG-- 325

Query: 375 NHPC---RFDTNTRVLASCGFSSGRHHWEV--EVGSKDGWAFGVARESVRRKGLTPFTPE 429
           +  C   RF      +    FSSGRH+WEV   +     WA GV R++V RK   P  PE
Sbjct: 326 SGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPE 385

Query: 430 EGVWALQLNGGQYWAVTSPERSPLSCGH-LSRVRVALDLEVGAVSFYAVEDMRHLYTF-R 487
            G W +QL+ G  +  T    +P+      S + + LD E G VSFY+V D  HL+T+ +
Sbjct: 386 NGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQ 445

Query: 488 VNFQERVFPLF 498
             F   + P F
Sbjct: 446 ATFPGPLQPFF 456


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  243 bits (621), Expect = 2e-64
 Identities = 168/502 (33%), Positives = 246/502 (49%), Gaps = 50/502 (9%)

Query: 18  ALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLP 77
           AL   +  E  C IC+   REP+S++CGHSFC +C+   WE PG       T        
Sbjct: 5   ALVEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYT-------- 56

Query: 78  CPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPF 137
           CP CR P +P  LRPN QLA V   +R   L     G  G            C +HGE  
Sbjct: 57  CPLCRAPVQPRNLRPNWQLANVVEKVRLLRLHPGM-GLKGDL----------CERHGEKL 105

Query: 138 KLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRST 197
           K++C++D   +C  C ++ EH  H+V+P+++   E K  L   L  LKKE E+       
Sbjct: 106 KMFCKEDVLIMCEACSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVG 165

Query: 198 EKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEG--RLLGR-----LEELSREVA---Q 247
           E+K +     Q+   ++ +  EF+  +  L +++   R LG      L  L RE A   Q
Sbjct: 166 ERKRTATWKIQVETRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQ 225

Query: 248 KQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEM 307
           K   N ++L  +   L ++ ++++E +Q+P    LQ+ +  L+R  +    +P  +S E+
Sbjct: 226 KLELNHSELIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLEL 285

Query: 308 KNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLG 367
           K        +   L+ +LK +  D+R            LDPDTA  RLI+S D K V  G
Sbjct: 286 KT-----DCRVLGLREILKTYAADVR------------LDPDTAYSRLIVSEDRKRVHYG 328

Query: 368 ERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFT 427
           +  Q LP++P RF     VL S   SSGRH+WEVEVG +  W  GV +++V RK +   +
Sbjct: 329 DTNQKLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCKQNVDRKEVVYLS 388

Query: 428 PEEGVWALQLNGGQYWAVTSPERSPLSCG-HLSRVRVALDLEVGAVSFYAVEDM-RHLYT 485
           P  G W ++L  G  +   + E   LS      RV + +D E   +SFY V D   H++T
Sbjct: 389 PHYGFWVIRLRKGNEYRAGTDEYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFT 448

Query: 486 F-RVNFQERVFPLFSVC-STGT 505
           F R  F  R+ P FS C S GT
Sbjct: 449 FPRYPFPGRLLPYFSPCYSIGT 470


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score =  237 bits (605), Expect = 2e-62
 Identities = 171/537 (31%), Positives = 255/537 (47%), Gaps = 114/537 (21%)

Query: 20  AAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCP 79
           A ++Q E TC ICL+ F++PVS+ECGH+FCR C+ R W  PG G           P PCP
Sbjct: 3   AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNW-APGGG-----------PFPCP 50

Query: 80  QCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKL 139
           +CR P+ P+ LRPN  LA +    +R  L    PG               CG+H EP +L
Sbjct: 51  ECRHPSAPAALRPNWALARLTEKTQRRRLGPVPPG--------------LCGRHWEPLRL 96

Query: 140 YCQDDGRAICVVCDRAREHREHAVLPLDEAVQ---------------------------E 172
           +C+DD R +C+VC  ++EH+ HA+ P+DEA +                           +
Sbjct: 97  FCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQ 156

Query: 173 AKELLESRLRVLKK-----ELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFL 227
            ++LL+S+  ++ K      L+D EV  +T+ K+      ++ +++ ++  EF  L  FL
Sbjct: 157 EEKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKD------KIKSQRMRISTEFSKLHNFL 210

Query: 228 VEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKS 287
           VE+E   L RL +   E  +K NEN  +L   I  L KL  ++ E +Q P L+ LQ  K 
Sbjct: 211 VEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKE 270

Query: 288 TLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLD 347
            L+R             SE+++   N SL+   +K +    +  L  E+ K  +V + L 
Sbjct: 271 VLTR-------------SEIQDV--NYSLEAVKVKTVC---QIPLMKEMLKRFQVAVNLA 312

Query: 348 PDTANPRLILSLDLKGVRLGERAQDLPNHPC------------------RFDTNTRVLAS 389
            DTA+P+L+ S + + V+    A   P                      RF     VL  
Sbjct: 313 EDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGK 372

Query: 390 CGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLT---PFTPEEGVWALQLNGGQYWAV- 445
             F+SG+H+WEVE       A GV RE V   G+T     +P+ G+WA+  +   YW + 
Sbjct: 373 NVFTSGKHYWEVESRDSLEVAVGVCREDV--MGITDRSKMSPDVGIWAIYWSAAGYWPLI 430

Query: 446 ----TSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLF 498
               T  ++ P     L RV V LD   G VSFY+  D  HL+TF  +   R+ P F
Sbjct: 431 GFPGTPTQQEPA----LHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFF 483


>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
          Length = 539

 Score =  235 bits (600), Expect = 6e-62
 Identities = 161/546 (29%), Positives = 260/546 (47%), Gaps = 73/546 (13%)

Query: 23  LQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCR 82
           L+ E TCSICL+  R+PV+++CGH FCR+C      RP +GS             CP C+
Sbjct: 10  LEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDV--RPISGSRPV----------CPLCK 57

Query: 83  EPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQ 142
           +P +   +RP  QLA++   + R  +     G    +    +  A  C +H E    YC+
Sbjct: 58  KPFKKENIRPVWQLASLVENIERLKVDK---GRQPGEVTREQQDAKLCERHREKLHYYCE 114

Query: 143 DDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKES 202
           DDG+ +CV+C  +REHR H  + +++A Q  +E + + L  L+++ +  + F++  + + 
Sbjct: 115 DDGKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADI 174

Query: 203 KELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQ 262
              LK++  +++ + AEF+    FL E+E  LL +L +L +E+ + + +  ++   E+ +
Sbjct: 175 LAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELAR 234

Query: 263 LSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLK 322
           L+ + S+++  AQ+P  + +Q+ +  L+R           ++  +K K    S K   L+
Sbjct: 235 LALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQ 294

Query: 323 GMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDT 382
             L++F+  L  +LE +  V +TLDP +A+  L LS D K V      +    HP +FD 
Sbjct: 295 RGLREFQGKLLRDLEYKT-VSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDC 353

Query: 383 NTRVLASCGFSSGRHHWEV---------------------------EVGSKDGW------ 409
              VL S GF+ G+ +WEV                           E G  DG+      
Sbjct: 354 EPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETD 413

Query: 410 ------------------------AFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAV 445
                                     GVAR+SV+RKG     PE+GVWAL+L+    WA 
Sbjct: 414 EDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWAN 473

Query: 446 TSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGT 505
           TSPE          RV +ALD E G V+F   E    +YTF   F  R+ P   +   GT
Sbjct: 474 TSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGT 533

Query: 506 YLRIWP 511
            L + P
Sbjct: 534 RLLLRP 539


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  229 bits (584), Expect = 4e-60
 Identities = 145/496 (29%), Positives = 236/496 (47%), Gaps = 36/496 (7%)

Query: 14  AEALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPP 73
           A A AL   LQ EA CSICL+   +PV++ECGH+FCR+CI + W                
Sbjct: 2   AVAAALTG-LQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLDLQE----------- 49

Query: 74  FPLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQH 133
              PCP CR   +    R N QL  +  + +          +        +     C +H
Sbjct: 50  -LFPCPVCRHQCQEGHFRSNTQLGRMIEIAKLL--------QSTKSNKRKQEETTLCEKH 100

Query: 134 GEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEV 193
            +P  ++C++D   +C +C +  +H+ H V P+++A    ++   S ++ LKK+L D + 
Sbjct: 101 NQPLSVFCKEDLMVLCPLCTQPPDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQK 160

Query: 194 FRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENL 253
             ST+ K+  EL + +  +++++ +EF+ L  FL  ++  +L RL E  ++  QK + N+
Sbjct: 161 LISTQSKKPLELREMVENQRQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANI 220

Query: 254 AQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWN 313
                    L    S++ E ++  +L+ L + K      +      P+  S  +K    +
Sbjct: 221 TAFSNYSATLKSQLSKVVELSELSELELLSQIKIFYESENE---SSPSIFSIHLKRDGCS 277

Query: 314 VSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDL 373
              +   L+ ++KKFK            VE+ LDP+TA+P LI+S D K VR  +R Q +
Sbjct: 278 FPPQYSALQRIIKKFK------------VEIILDPETAHPNLIVSEDKKRVRFTKRKQKV 325

Query: 374 PNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVW 433
           P  P RF     VL    F SGRH WE+EVG K  WA G+ ++S+  K   P + ++  W
Sbjct: 326 PGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGDKSEWAIGICKDSLPTKARRPSSAQQECW 385

Query: 434 ALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQER 493
            ++L    Y A  +     L       + + LD E+G +SFY + +  H+ TF   F   
Sbjct: 386 RIELQDDGYHAPGAFPTPLLLEVKARAIGIFLDYEMGEISFYNMAEKSHICTFTDTFTGP 445

Query: 494 VFPLFSVCSTGTYLRI 509
           + P F V      LRI
Sbjct: 446 LRPYFYVGPDSQPLRI 461


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  227 bits (579), Expect = 2e-59
 Identities = 160/486 (32%), Positives = 238/486 (48%), Gaps = 49/486 (10%)

Query: 22  ELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQC 81
           ++  EATCSICL L   PVS+ CGHS+C  CI   ++ P    +   T        CPQC
Sbjct: 9   KMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFC------CPQC 62

Query: 82  REPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYC 141
           R P     LRPN+QL ++   L+      +                  C +HGE F L+C
Sbjct: 63  RAPFHMDSLRPNKQLGSLIEALKETDQEMS------------------CEEHGEQFHLFC 104

Query: 142 QDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKE 201
           +D+G+ IC  C+RA +H+ H    +++  Q  KE L+  +  L K+LED    R TE+K 
Sbjct: 105 EDEGQLICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKL-KQLED----RCTEQKL 159

Query: 202 SKEL-----LKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQL 256
           S  +      +++  +++K+ ++F+ L+ FL E+E   L RLE+  ++   +  +  A L
Sbjct: 160 STAMRITKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGL 219

Query: 257 GVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSL 316
           G++  +L     +++E  Q      LQ    TLSR   V       VS E+ + + NVS 
Sbjct: 220 GLKSNELKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLEL-HTMCNVSK 278

Query: 317 KTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNH 376
             F +K ML            +  +V +TLDPDTA+  LILS D + V  G   ++    
Sbjct: 279 LYFDVKKML------------RSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTS 326

Query: 377 PCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQ 436
             RF     VL   GF+SGR ++EV+VG   GW  GV  E+V+R       P+ G W L+
Sbjct: 327 SRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLR 386

Query: 437 L-NGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTF-RVNFQERV 494
           L     Y A+TSP  S         V + LD E G VSFY      H++TF + +F + +
Sbjct: 387 LCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTL 446

Query: 495 FPLFSV 500
            P F V
Sbjct: 447 RPYFQV 452


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score =  227 bits (578), Expect = 2e-59
 Identities = 133/383 (34%), Positives = 203/383 (53%), Gaps = 21/383 (5%)

Query: 18  ALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLP 77
           A    L  E  C IC    REPV+++CGH+FCRAC+ R  E PG     + T        
Sbjct: 5   ASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPT-------- 56

Query: 78  CPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAP-GEHGSQAAAARAAAARCGQHGEP 136
           CP C+EP RP   RPN QLA V   + R  L +    GE              C +HGE 
Sbjct: 57  CPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDV-----------CQEHGEK 105

Query: 137 FKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRS 196
              +C+DD   +CVVC  A EH  H +  L++A    +E +   L+ L+KE E+ +  +S
Sbjct: 106 IYFFCEDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQS 165

Query: 197 TEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQL 256
            E K  + LL Q++ ++++V +EF  LR FL EQ+  LL +LE    ++ ++++E    +
Sbjct: 166 RENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLV 225

Query: 257 GVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSL 316
             EI + S L  +++E  ++P  + L + +STL RC      KP  VS E+  ++ +   
Sbjct: 226 AGEICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQ 285

Query: 317 KTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNH 376
           +   L+  +K F E L  EL+  E   ++LDP T++P+L+LS D +  +   + Q+ P++
Sbjct: 286 QALPLQREMKMFLEKLCFELD-YEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDN 344

Query: 377 PCRFDTNTRVLASCGFSSGRHHW 399
           P RFD  T VLA  G + GRH W
Sbjct: 345 PQRFDRATCVLAHTGITGGRHTW 367


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score =  213 bits (542), Expect = 3e-55
 Identities = 153/462 (33%), Positives = 219/462 (47%), Gaps = 43/462 (9%)

Query: 44  CGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREPARPSQLRPNRQLAAVATLL 103
           CGH+FCRACI   WE+   G  G   R   FP  CP+CRE +    L PNR L  VA + 
Sbjct: 4   CGHNFCRACIQLSWEK-ARGKKGRRKRKGSFP--CPECREMSPQRNLLPNRLLTKVAEMA 60

Query: 104 RRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQDDGRAICVVCDRAREHREHAV 163
           ++       PG               C +H EP KL+CQ D   ICVVC  +REHR H V
Sbjct: 61  QQH------PGLQKQDL---------CQEHHEPLKLFCQKDQSPICVVCRESREHRLHRV 105

Query: 164 LPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQAL 223
           LP +EAVQ  K  LE  +  L++++      ++ E++   E   ++   +E++  EF+ +
Sbjct: 106 LPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKM 165

Query: 224 RAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQ 283
             +LVE+E RLL  LE    E A +  E++A L  +   L  L  Q++E + +  L  LQ
Sbjct: 166 NLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQ 225

Query: 284 EFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVE 343
           + K  LSR +NV    P          V  V  +  VL+G L+                +
Sbjct: 226 DMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLE----------------D 269

Query: 344 LTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPC---RFDTNTRVLASCGFSSGRHHWE 400
           +  D  +A P L+L    +   LG   +   +  C   RF      +    FSSGRH+WE
Sbjct: 270 VVPDATSAYPYLLLYESRQRRYLGSSPEG--SGFCSKDRFVAYPCAVGQTAFSSGRHYWE 327

Query: 401 V--EVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGH- 457
           V   +     WA GV R++V RK   P  PE G W +QL+ G  +  T    +P+     
Sbjct: 328 VGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEP 387

Query: 458 LSRVRVALDLEVGAVSFYAVEDMRHLYTF-RVNFQERVFPLF 498
            S + + LD E G VSFY+V D  HL+T+ +  F   + P F
Sbjct: 388 PSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFF 429


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  212 bits (539), Expect = 7e-55
 Identities = 152/487 (31%), Positives = 235/487 (48%), Gaps = 48/487 (9%)

Query: 19  LAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPC 78
           L   L+ E TC ICL+ F  PV+ ECGHSFC  C+ R WE                PL C
Sbjct: 6   LMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNT------------PLSC 53

Query: 79  PQCREPARPSQLRPNRQLAAVATLLRRF-SLPAAAPGEHGSQAAAARAAAARCGQHGEPF 137
           P+C         + N +L  +A++ R+  S    +  E GS       A A         
Sbjct: 54  PECWRTLEGPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKA--------- 104

Query: 138 KLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRST 197
            L   + G +  V    A+ H  + V    EA +  +E L+  L +L+   ++ +   + 
Sbjct: 105 -LSDDEQGGSAFV----AQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTH 159

Query: 198 EKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLG 257
           EK+  K   ++    ++ V +E+  +  FL E+E   L  LE+  +E  +K   N  +L 
Sbjct: 160 EKERVKLCQEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLT 219

Query: 258 VEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLK 317
            +I  LSK+ +QI+ ++Q    + L+E +  L R   +    P   ++E+         +
Sbjct: 220 QQIRSLSKMIAQIESSSQSSAFESLEEVRGALERSEPLLLQCPEATTTELS------LCR 273

Query: 318 TFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHP 377
              +K ML+KF              E+TLDP TAN  L+LS DLK V+ G   Q LP++P
Sbjct: 274 ITGMKEMLRKFS------------TEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNP 321

Query: 378 CRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQL 437
            RFD +  VL +  F+SGRH+WEVEVG+K  W  G+ ++SV RKG  P  P +    + L
Sbjct: 322 ERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGL 381

Query: 438 NGGQYWA--VTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTF-RVNFQERV 494
             G  ++  V+SP +       + +V V LD E G ++FY   D   +Y+F + +FQE +
Sbjct: 382 KIGDDYSLWVSSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEAL 441

Query: 495 FPLFSVC 501
            P+FS C
Sbjct: 442 RPIFSPC 448


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  211 bits (536), Expect = 2e-54
 Identities = 136/496 (27%), Positives = 240/496 (48%), Gaps = 35/496 (7%)

Query: 15  EALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPF 74
           E +     LQ E++C ICLE  ++PV++ CGH+FCR+C+   W+                
Sbjct: 2   EFVTALVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDD------------ 49

Query: 75  PLPCPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHG 134
             PCP CR        R N QL  +  + ++  +  +        A         C +H 
Sbjct: 50  TFPCPVCRFCFPYKSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAM--------CEKHN 101

Query: 135 EPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVF 194
           +   L+C  D   +C  C  + +H++H + P+ +A    +E+LE  L  L+  +E  E  
Sbjct: 102 QFLTLFCVKDLEILCTQCSFSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKV 161

Query: 195 RSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLA 254
              +  +S EL K++  ++E++ +EF+ +R FL  ++  +L ++++    +  K NENL 
Sbjct: 162 IILQGSKSVELKKKVEYKREEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLV 221

Query: 255 QLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNV 314
           +L   ++ L  L  +++  + + +L+ L + KS   +  N+  P+    S  +    +++
Sbjct: 222 ELSDYVSTLKHLLREVEGKSVQSNLELLTQAKSMHHKYQNLKCPE--LFSFRLTKYGFSL 279

Query: 315 SLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLP 374
             +   L  ++K F            +V++ LD +TA+P+L++S D K VR   + +++ 
Sbjct: 280 PPQYSGLDRIIKPF------------QVDVILDLNTAHPQLLVSEDRKAVRYERKKRNIC 327

Query: 375 NHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWA 434
             P RF     VL S  FSSGRH+WEVEVG+K  W  GV ++ + R      +   G WA
Sbjct: 328 YDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKPKWILGVCQDCLLRNWQDQPSVLGGFWA 387

Query: 435 LQLNGGQYWAVTSPERSP-LSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQER 493
           +       +  + P+ +  L     S++ + LD E+G +SFY + D   LYTF   F E 
Sbjct: 388 IGRYMKSGYVASGPKTTQLLPVVKPSKIGIFLDYELGDLSFYNMNDRSILYTFNDCFTEA 447

Query: 494 VFPLFSVCSTGTYLRI 509
           V+P F   +    L+I
Sbjct: 448 VWPYFYTGTDSEPLKI 463


>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score =  206 bits (525), Expect = 3e-53
 Identities = 144/480 (30%), Positives = 223/480 (46%), Gaps = 38/480 (7%)

Query: 26  EATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREPA 85
           E  C +C + FR+P+ + CGH+FC ACI   W      +             CP+C+   
Sbjct: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETF------------CPECKMLC 85

Query: 86  RPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQDDG 145
           + +    N  L  +   +++  L    P               +C +HGE  KL+ + DG
Sbjct: 86  QYNNCTFNPVLDKLVEKIKKLPLLKGHP---------------QCPEHGENLKLFSKPDG 130

Query: 146 RAICVVCDRAREH--REHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKESK 203
           + IC  C  AR    +    L + +AV    E L  +   L+  L++ +  R+ +K+   
Sbjct: 131 KLICFQCKDARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIA 190

Query: 204 ELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQL 263
              +     Q+ V  EF  L  FL  +E  +L  L E  + + ++   NL+QL  +    
Sbjct: 191 AHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLA 250

Query: 264 SKLSSQIQ-ETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLK 322
             +   IQ +T Q+   DFL++  + L       G K       +  K+     K  +  
Sbjct: 251 KDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQ--GMKVLATRELISRKLNLGQYKGPIQY 308

Query: 323 GMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDT 382
            + ++ ++ L   L       LTLDP TA+P L+LS     V  G+  + +P+ P RFD+
Sbjct: 309 MVWREMQDTLCPGLSP-----LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDS 363

Query: 383 NTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQL-NGGQ 441
           +  VL S GF+SG+ +WEVEV  K  W  GV RES+ RKG  P TPE+G W L+L N   
Sbjct: 364 SVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTD 423

Query: 442 YWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVC 501
             A+  P  S     +L +V + LD E G +SFY  + M H+YTF   F E+++P F  C
Sbjct: 424 LKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPC 483


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  206 bits (524), Expect = 4e-53
 Identities = 152/500 (30%), Positives = 238/500 (47%), Gaps = 50/500 (10%)

Query: 22  ELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQC 81
           +++ E TC ICLEL  EP+S++CGHSFC+ACI         G  G  +        CP C
Sbjct: 8   DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS--------CPVC 59

Query: 82  REPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYC 141
           +   +P  LRPNR LA +   LR   L    PG+        +  A  C  HGE  +L+C
Sbjct: 60  QTSYQPGNLRPNRHLANIVRRLREVVL---GPGK--------QLKAVLCADHGEKLQLFC 108

Query: 142 QDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKE 201
           Q+DG+ IC +C+R++EHR H    ++E  QE +E  +  L+ LK E ++ E   +  +++
Sbjct: 109 QEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREK 168

Query: 202 SKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEIT 261
                 QM  E+ ++  EF  LR  L   E R L +LE+  ++  +   E    L  +  
Sbjct: 169 KTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQ 228

Query: 262 QLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVL 321
            L +L S ++   Q   ++ LQ+      R       KP  + +++++       +   L
Sbjct: 229 SLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS-----MFRAPDL 283

Query: 322 KGMLKKFKE--DLRGELEKEEKVELTLDPDTANPRLILSLDLKGVR-LGERAQDLPNHPC 378
           K ML+  +E  D++        V++TL+P TAN  L+L+ + + VR +G +         
Sbjct: 284 KRMLRVCRELTDVQSYW-----VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK 338

Query: 379 RFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESV-----------RRKGLTPFT 427
            +D +  VL S  FSSG+H+WEV+V  K  W  GV   S+                + + 
Sbjct: 339 HYDCS--VLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQ 396

Query: 428 PEEGVWALQL-NGGQYWAVTSPERSPLSCGHL--SRVRVALDLEVGAVSFYAVEDMRH-L 483
           P+ G W + L +  +Y A      S L    +   RV V LD E G VSFY V +    +
Sbjct: 397 PQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPI 456

Query: 484 YTF-RVNFQERVFPLFSVCS 502
           YTF +  F   + P F+ C+
Sbjct: 457 YTFSKYYFPTTLCPYFNPCN 476


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  206 bits (524), Expect = 4e-53
 Identities = 152/500 (30%), Positives = 238/500 (47%), Gaps = 50/500 (10%)

Query: 22  ELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQC 81
           +++ E TC ICLEL  EP+S++CGHSFC+ACI         G  G  +        CP C
Sbjct: 36  DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS--------CPVC 87

Query: 82  REPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYC 141
           +   +P  LRPNR LA +   LR   L    PG+        +  A  C  HGE  +L+C
Sbjct: 88  QTSYQPGNLRPNRHLANIVRRLREVVL---GPGK--------QLKAVLCADHGEKLQLFC 136

Query: 142 QDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKE 201
           Q+DG+ IC +C+R++EHR H    ++E  QE +E  +  L+ LK E ++ E   +  +++
Sbjct: 137 QEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREK 196

Query: 202 SKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEIT 261
                 QM  E+ ++  EF  LR  L   E R L +LE+  ++  +   E    L  +  
Sbjct: 197 KTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQ 256

Query: 262 QLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVL 321
            L +L S ++   Q   ++ LQ+      R       KP  + +++++       +   L
Sbjct: 257 SLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRS-----MFRAPDL 311

Query: 322 KGMLKKFKE--DLRGELEKEEKVELTLDPDTANPRLILSLDLKGVR-LGERAQDLPNHPC 378
           K ML+  +E  D++        V++TL+P TAN  L+L+ + + VR +G +         
Sbjct: 312 KRMLRVCRELTDVQSYW-----VDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEK 366

Query: 379 RFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESV-----------RRKGLTPFT 427
            +D +  VL S  FSSG+H+WEV+V  K  W  GV   S+                + + 
Sbjct: 367 HYDCS--VLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQ 424

Query: 428 PEEGVWALQL-NGGQYWAVTSPERSPLSCGHL--SRVRVALDLEVGAVSFYAVEDMRH-L 483
           P+ G W + L +  +Y A      S L    +   RV V LD E G VSFY V +    +
Sbjct: 425 PQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPI 484

Query: 484 YTF-RVNFQERVFPLFSVCS 502
           YTF +  F   + P F+ C+
Sbjct: 485 YTFSKYYFPTTLCPYFNPCN 504


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,078,001
Number of Sequences: 37866
Number of extensions: 1033155
Number of successful extensions: 7018
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 289
Number of HSP's successfully gapped in prelim test: 485
Number of HSP's that attempted gapping in prelim test: 5533
Number of HSP's gapped (non-prelim): 1463
length of query: 511
length of database: 18,247,518
effective HSP length: 107
effective length of query: 404
effective length of database: 14,195,856
effective search space: 5735125824
effective search space used: 5735125824
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.