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Search of human proteins with 126722969
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|126722969 centromere protein T [Homo sapiens]
(561 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|126722969 centromere protein T [Homo sapiens] 1111 0.0
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 57 4e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 54 5e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 52 1e-06
gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 52 1e-06
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 48 2e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 3e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 44 3e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 44 3e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 44 3e-04
gi|4885379 histone cluster 1, H1e [Homo sapiens] 44 5e-04
gi|55741677 SET domain containing 1A [Homo sapiens] 43 7e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 42 0.001
gi|45120115 hypothetical protein LOC56905 [Homo sapiens] 40 0.004
gi|157738619 smoothelin-like 1 [Homo sapiens] 40 0.004
gi|221139926 NHS-like 1 [Homo sapiens] 40 0.006
gi|223972704 hypothetical protein LOC284418 [Homo sapiens] 40 0.006
gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens] 40 0.007
gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens] 40 0.007
gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens] 40 0.007
gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens] 40 0.007
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 40 0.007
gi|145386517 phostensin [Homo sapiens] 40 0.007
gi|199559805 phostensin [Homo sapiens] 40 0.007
gi|61966919 hypothetical protein LOC442444 [Homo sapiens] 39 0.010
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 39 0.013
gi|55749431 transcription elongation factor A (SII)-like 3 [Homo... 39 0.013
gi|14249718 transcription elongation factor A (SII)-like 3 [Homo... 39 0.013
gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens] 39 0.017
gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens] 39 0.017
>gi|126722969 centromere protein T [Homo sapiens]
Length = 561
Score = 1111 bits (2874), Expect = 0.0
Identities = 561/561 (100%), Positives = 561/561 (100%)
Query: 1 MADHNPDSDSTPRTLLRRVLDTADPRTPRRPRSARAGARRALLETASPRKLSGQTRTIAR 60
MADHNPDSDSTPRTLLRRVLDTADPRTPRRPRSARAGARRALLETASPRKLSGQTRTIAR
Sbjct: 1 MADHNPDSDSTPRTLLRRVLDTADPRTPRRPRSARAGARRALLETASPRKLSGQTRTIAR 60
Query: 61 GRSHGARSVGRSAHIQASGHLEEQTPRTLLKNILLTAPESSILMPESVVKPVPAPQAVQP 120
GRSHGARSVGRSAHIQASGHLEEQTPRTLLKNILLTAPESSILMPESVVKPVPAPQAVQP
Sbjct: 61 GRSHGARSVGRSAHIQASGHLEEQTPRTLLKNILLTAPESSILMPESVVKPVPAPQAVQP 120
Query: 121 SRQESSCGSLELQLPELEPPTTLAPGLLAPGRRKQRLRLSVFQQGVDQGLSLSQEPQGNA 180
SRQESSCGSLELQLPELEPPTTLAPGLLAPGRRKQRLRLSVFQQGVDQGLSLSQEPQGNA
Sbjct: 121 SRQESSCGSLELQLPELEPPTTLAPGLLAPGRRKQRLRLSVFQQGVDQGLSLSQEPQGNA 180
Query: 181 DASSLTRSLNLTFATPLQPQSVQRPGLARRPPARRAVDVGAFLRDLRDTSLAPPNIVLED 240
DASSLTRSLNLTFATPLQPQSVQRPGLARRPPARRAVDVGAFLRDLRDTSLAPPNIVLED
Sbjct: 181 DASSLTRSLNLTFATPLQPQSVQRPGLARRPPARRAVDVGAFLRDLRDTSLAPPNIVLED 240
Query: 241 TQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEA 300
TQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEA
Sbjct: 241 TQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEA 300
Query: 301 EEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEE 360
EEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEE
Sbjct: 301 EEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEE 360
Query: 361 AEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESLQARRHHQFLEPA 420
AEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESLQARRHHQFLEPA
Sbjct: 361 AEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESLQARRHHQFLEPA 420
Query: 421 PAPGAAVLSSEPAEPLLVRHPPRPRTTGPRPRQDPHKAGLSHYVKLFSFYAKMPMERKAL 480
PAPGAAVLSSEPAEPLLVRHPPRPRTTGPRPRQDPHKAGLSHYVKLFSFYAKMPMERKAL
Sbjct: 421 PAPGAAVLSSEPAEPLLVRHPPRPRTTGPRPRQDPHKAGLSHYVKLFSFYAKMPMERKAL 480
Query: 481 EMVEKCLDKYFQHLCDDLEVFAAHAGRKTVKPEDLELLMRRQGLVTDQVSLHVLVERHLP 540
EMVEKCLDKYFQHLCDDLEVFAAHAGRKTVKPEDLELLMRRQGLVTDQVSLHVLVERHLP
Sbjct: 481 EMVEKCLDKYFQHLCDDLEVFAAHAGRKTVKPEDLELLMRRQGLVTDQVSLHVLVERHLP 540
Query: 541 LEYRQLLIPCAYSGNSVFPAQ 561
LEYRQLLIPCAYSGNSVFPAQ
Sbjct: 541 LEYRQLLIPCAYSGNSVFPAQ 561
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 57.0 bits (136), Expect = 4e-08
Identities = 94/431 (21%), Positives = 152/431 (35%), Gaps = 67/431 (15%)
Query: 60 RGRSHGARSVGRSAHIQASGHLEEQTPRTLLKNILLTAPESSILMPESVVKPVPAPQA-- 117
RGR A++ G A G+ ++ P T L + P S PE V K AP+A
Sbjct: 2332 RGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARP 2391
Query: 118 --VQPSRQESSCGSLELQLPELE---PPTTLAPGLLA--PGRRKQRLRLSVFQQGVDQGL 170
QPS + S P E P T+LAP L P R + + ++ +G
Sbjct: 2392 APPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKG- 2450
Query: 171 SLSQEPQGNADASSLTRSLNLTFATPLQPQSVQRPGLARRPPARRAVDVGAFLRDLRDTS 230
P+ + + L L+ T + + + L R P G +
Sbjct: 2451 -----PRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPG-----AGGWQE------ 2494
Query: 231 LAPPNIVLEDTQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPG 290
P +++ + P P GS S P P A D + A Q GPGL G
Sbjct: 2495 --PKSLLSLGSYP---PAAGS-----SEPKAPWPKATDGDLA-----QEPGPGLTFEDSG 2539
Query: 291 KP-----AQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKME------- 338
P AQ AEE + + +SS S +G EE +K +
Sbjct: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGG 2599
Query: 339 -------EEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDEDA 391
S + ++ + S + + + + S ++ + +SS +
Sbjct: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2659
Query: 392 SGRAASPESASSTPESLQARRHHQFLEPAPAPGAAVLSSEPAEPLL-------VRHPPRP 444
S ++S S+SST + + PAP G + ++ P + H P
Sbjct: 2660 SSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGK 2719
Query: 445 RTTGPRPRQDP 455
+T P+P+ P
Sbjct: 2720 KTPAPQPQAPP 2730
Score = 32.7 bits (73), Expect = 0.91
Identities = 46/183 (25%), Positives = 70/183 (38%), Gaps = 23/183 (12%)
Query: 169 GLSLSQEPQGNADASSLTRSLNLTFATPLQPQSVQRPGLARRPPARRAVDVGAFLRDLRD 228
GLSL +G ++ TR + + F QP+S P A +V ++ +
Sbjct: 1685 GLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAHSP---------FASEVSSY---SYN 1732
Query: 229 TSLAPPNIVLEDTQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNS 288
T L+D P P S + SL C+ A++++ A G K G +
Sbjct: 1733 TDSEEDEEFLKDEWPAQGP--SSSKLTPSLLCS--MVAKNSKAAGGPKLTKRGLAAPRTL 1788
Query: 289 PGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEME 348
KPA F L + S D E D E +E++ EEE + E E
Sbjct: 1789 KPKPA------TSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELE-EEDE 1841
Query: 349 ATG 351
A+G
Sbjct: 1842 ASG 1844
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 53.5 bits (127), Expect = 5e-07
Identities = 101/460 (21%), Positives = 173/460 (37%), Gaps = 49/460 (10%)
Query: 24 DPRTPRRPRSARAGARRALLETASPRKLSGQTRTIARGRSHGARSVGRSAHIQASGHLEE 83
D +R + + +R + SPR+ ++ + R RS R + +H ++ H +
Sbjct: 148 DEDKDKRDKEEKESSREKRERSRSPRRRKSRSPS-PRRRSSPVRRERKRSHSRSPRHRTK 206
Query: 84 QTPRTLLKNILLTAPESSILMPESVVKPVPAPQAVQPSRQESSCGSLELQLPELEP-PTT 142
+ APE PE P P+ + +PS QE++ S L++P+ EP P
Sbjct: 207 SRSPS-------PAPEKKEKTPEL---PEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP 256
Query: 143 LAPGLLAPGRR---KQRLRLSVFQQGVDQGLSLSQEPQGNADASSLTRSLNLTFATPLQP 199
P ++ K++ R + + + S+ P + RS + +++ +P
Sbjct: 257 KEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPS-HTRPRRRHRSRSRSYSPRRRP 315
Query: 200 QSVQRPGLARRPPARRAVDVGAFLRDLRDTSLAPPNIVLEDTQPFS-QPMVGSPNVYHSL 258
+RP RR P RR R S +P + S S + S
Sbjct: 316 SPRRRPSPRRRTPPRRMPPPPRHRR-----SRSPVRRRRRSSASLSGSSSSSSSSRSRSP 370
Query: 259 PCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQ-----FLAGEAEEVNAFALGFLST 313
P P + R + S+ P +++ P PA + ++ N +S
Sbjct: 371 PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV 430
Query: 314 SSGVSGEDEVEPLHDGVEEAEK-----KMEEEGVSVSEMEATGAQGPS-----RVEEAEG 363
S G + + H G E+ E K + +S SE + G + R +
Sbjct: 431 SPGRTSGKVTK--HKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQ 488
Query: 364 HTEVTEAEGSQGTAEADGPGAS---SGDEDASGRAASPESASSTPESLQAR---RHHQFL 417
+ + + GS ++E + P S +G+ R + SAS +P Q R +
Sbjct: 489 NQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRR 548
Query: 418 EPAPAPGAAVLSSEPAEPLLVRH----PPRPRTTGPRPRQ 453
P+P P S PA P R PPR RT P PR+
Sbjct: 549 SPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRR 588
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 52.4 bits (124), Expect = 1e-06
Identities = 45/184 (24%), Positives = 70/184 (38%), Gaps = 23/184 (12%)
Query: 262 PHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSG-- 319
P T E ++ G + + Q S G AQ GEA+ S G+
Sbjct: 2119 PETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQP----------ESEGIEAQE 2168
Query: 320 -EDEVEPLHDGVE----EAEKKMEEEGVSVSEMEAT------GAQGPSRVEEAEGHTEVT 368
E+E +P +GVE E E + E EG+ E E G + P EEA+ E
Sbjct: 2169 AEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGV 2228
Query: 369 EAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESLQARRHHQFLEPAPAPGAAVL 428
E ++G A+ + G + G++ S + + + S + P P+PG
Sbjct: 2229 ETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTP 2288
Query: 429 SSEP 432
P
Sbjct: 2289 HQRP 2292
Score = 48.5 bits (114), Expect = 2e-05
Identities = 52/184 (28%), Positives = 74/184 (40%), Gaps = 16/184 (8%)
Query: 267 EDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPL 326
++AE+ A + +S G Q S G+ AQ + GE ++ A E+E +
Sbjct: 2010 QEAEEEA--QPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEA 2067
Query: 327 HDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASS 386
V+EAE + E V EA G P E+EG E EAEG AE +
Sbjct: 2068 EGEVQEAEGEAHPESEDVDAQEAEGEAQP----ESEG-VEAPEAEGEAQKAEGIEAPETE 2122
Query: 387 GDEDASGRAASPESAS-STPESL-QARRHHQFLEPAPAPGAAVLSSEPAEPLLVRHPPRP 444
G+ A PES PE+ +A+ + +E A G A SE E +P
Sbjct: 2123 GE-------AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQP 2175
Query: 445 RTTG 448
G
Sbjct: 2176 ELEG 2179
Score = 47.0 bits (110), Expect = 5e-05
Identities = 50/194 (25%), Positives = 72/194 (37%), Gaps = 23/194 (11%)
Query: 264 TGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEV 323
+G ED Q PG + G A GEA+ + + E E
Sbjct: 1808 SGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEA 1867
Query: 324 EPLHDGVE----EAEKKMEEEGVSVSEME------ATGAQGPSRVEEAEGHTEVTEAEGS 373
+P + VE E E + E E V E E + GA+ P +EA+ TE EA +
Sbjct: 1868 QPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALET 1927
Query: 374 QGTAEADGPGASSGDEDASGRAA----SPES---------ASSTPESLQARRHHQFLEPA 420
+G E + GA + + + + + A PES + PES +E
Sbjct: 1928 EGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQ 1987
Query: 421 PAPGAAVLSSEPAE 434
A G A SE E
Sbjct: 1988 EAEGEAQPESEDVE 2001
Score = 45.1 bits (105), Expect = 2e-04
Identities = 57/198 (28%), Positives = 83/198 (41%), Gaps = 24/198 (12%)
Query: 262 PHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGED 321
P + E+A++ G +TQ + Q S G A EAEE A G + + G
Sbjct: 2027 PKSEGEEAQEVEG-ETQKTEGDAQPESDGVEAP----EAEEEAQEAEGEVQEAEG----- 2076
Query: 322 EVEPLHDGVE--EAEKKM--EEEGVSVSEME-----ATGAQGPSRVEEAEGHTEVTEAEG 372
E P + V+ EAE + E EGV E E A G + P EA+ +E EA
Sbjct: 2077 EAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPE 2136
Query: 373 SQGTAEADGPGASSGDEDASGRAASPESASSTPESL--QARRHHQFLEPAPAPGAAVLSS 430
++G A+ + G + +DA G A PES + +A+ + +E A G A S
Sbjct: 2137 AEGEAQPESEGVEA--QDAEGE-AQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPES 2193
Query: 431 EPAEPLLVRHPPRPRTTG 448
E E +P G
Sbjct: 2194 EGIEAPEAEGEAQPELEG 2211
Score = 43.9 bits (102), Expect = 4e-04
Identities = 44/148 (29%), Positives = 67/148 (45%), Gaps = 14/148 (9%)
Query: 266 AEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEP 325
AE+A Q A +TQ ++ + AQ E+E+V A + + + E E +P
Sbjct: 1943 AEEAAQEAEGQTQPESEVIESQEAEEEAQ---PESEDVEALEVEVETQEA----EGEAQP 1995
Query: 326 LHDGVE--EAEKKMEE-EGVSVSEMEATGAQGPSRVEEA---EGHTEVTEAEGSQGTAEA 379
+ VE EAE +M+E E + E + AQ S EEA EG T+ TE + +
Sbjct: 1996 ESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGV 2055
Query: 380 DGPGASSGDEDASGRAASPESASSTPES 407
+ P A ++A G E + PES
Sbjct: 2056 EAPEAEEEAQEAEGEVQEAE-GEAHPES 2082
Score = 43.9 bits (102), Expect = 4e-04
Identities = 51/184 (27%), Positives = 78/184 (42%), Gaps = 22/184 (11%)
Query: 267 EDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEA----EEVNA-FALGFLSTSSGVSG-- 319
E+A++A G ++ G S AQ GEA E V A A G + G+
Sbjct: 2062 EEAQEAEGEVQEAEGEA-HPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPE 2120
Query: 320 -EDEVEPLHDGVE----EAEKKMEEEGVSV------SEMEATGAQGPSRVEEAEGHTEVT 368
E E +P +G+E E E + E EGV ++ E+ G + EEA+ E
Sbjct: 2121 TEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGV 2180
Query: 369 EAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPES-LQARRHHQFLEPAPAPGAAV 427
EA ++G A+ + G + +A G A PE+ +A+ + +E A G A
Sbjct: 2181 EAPEAEGEAQPESEGIEA--PEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQ 2238
Query: 428 LSSE 431
SE
Sbjct: 2239 PESE 2242
Score = 41.6 bits (96), Expect = 0.002
Identities = 83/338 (24%), Positives = 121/338 (35%), Gaps = 46/338 (13%)
Query: 137 LEPPTTLAPG--LLAPGRRKQRLR----LSVFQQGV----DQGLSLSQEPQ-GNADASSL 185
LEPP G LL +R+ RLR LS F + +L EP A S L
Sbjct: 1588 LEPPREALTGELLLQTQQRRHRLRGLRNLSAFSERTLGLGPLSFTLEDEPALSTALGSQL 1647
Query: 186 TRSLNLTFATPLQ--------PQSVQRPGLARRPPARRAVDVGAFLRDLRDTSLAPPNIV 237
P + P S + A R P + A D+ L+ R
Sbjct: 1648 GEEAEGEEFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQILQRKRG--------- 1698
Query: 238 LEDTQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLA 297
E T + + +P H+ P + T + AE G S GPG+ + G+ +Q L
Sbjct: 1699 -EHTDGEAAEV--APGKTHTDPTSTRT-VQGAEGGLGPGL-SQGPGVDEGEDGEGSQRLN 1753
Query: 298 GEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSR 357
+ + A G G+ G E E E+EG +SE TG QG
Sbjct: 1754 RDKDPKLGEAEGDAMAQER-EGKTHNSETSAGSELGEA--EQEGEGISERGETGGQGSGH 1810
Query: 358 VEEAEGHTEVTEAEGSQGTAEADG------PGASSGDEDASGRAASPESASSTPESL-QA 410
+ +G A G Q ++DG P A + S +PE+ E+ +A
Sbjct: 1811 EDNLQGE---AAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEA 1867
Query: 411 RRHHQFLEPAPAPGAAVLSSEPAEPLLVRHPPRPRTTG 448
+ + +E A G A SE E +P + G
Sbjct: 1868 QPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEG 1905
Score = 40.4 bits (93), Expect = 0.004
Identities = 53/203 (26%), Positives = 80/203 (39%), Gaps = 27/203 (13%)
Query: 252 PNVYHSLPCTPHTGAEDAEQAAGRKTQSSG-PGLQKNSPGKPAQF------LAGEAEEVN 304
P ++ C T ++AE+ + + SS L +N+ + Q GE +
Sbjct: 1259 PTFLNARACACATNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEE 1318
Query: 305 AFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGH 364
A L T G+ ++E L + E + +EE + E+E TG +G EE
Sbjct: 1319 AVQLEETKTEEGL--QEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQ--EEGVQL 1374
Query: 365 TEVTEAE--GSQGTAEADGPGASSGDEDAS------GRAASPESASSTP----ESLQARR 412
EV E G QG A +G E+ S A+SP+ S + +A R
Sbjct: 1375 EEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGR 1434
Query: 413 HHQFLEPAPAPGAAVLSSEPAEP 435
EP PA G + EP EP
Sbjct: 1435 ASASAEPCPAEG----TEEPTEP 1453
Score = 36.6 bits (83), Expect = 0.063
Identities = 45/172 (26%), Positives = 69/172 (40%), Gaps = 17/172 (9%)
Query: 240 DTQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQ--FLA 297
+ QP S+ + + P + A +AE+ A +T+S L+ +P A
Sbjct: 1882 EAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESV-EALETEGEDEPESEGAEA 1940
Query: 298 GEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSR 357
EAEE A G S V E E EEA+ + E+ E+E A+G ++
Sbjct: 1941 QEAEEAAQEAEGQTQPESEVIESQEAE------EEAQPESEDVEALEVEVETQEAEGEAQ 1994
Query: 358 VEEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESLQ 409
E + E EAEG AE + S G E A P+S + ++
Sbjct: 1995 PESED--VEAPEAEGEMQEAEEEAQPESDGVE------AQPKSEGEEAQEVE 2038
>gi|148806908 fibronectin type III domain containing 1 [Homo
sapiens]
Length = 1894
Score = 52.0 bits (123), Expect = 1e-06
Identities = 76/311 (24%), Positives = 121/311 (38%), Gaps = 44/311 (14%)
Query: 121 SRQES--SCGSLELQLPELEPPTTLAPGLLAPGRRKQRLRLSVF--QQGVDQ-GLSLSQE 175
SR++S S + Q L PP+ ++APGR R R+ ++GVD+ G SL+ +
Sbjct: 548 SREDSPMSPSDTQDQKRTLRPPSRHGHSVVAPGRTAVRARMPALPRREGVDKPGFSLATQ 607
Query: 176 PQGNADASSLTRSLNLTFATPLQPQSVQRPGLARRPPARRAVDVGAFL---RDLRDTSLA 232
P+ A S+ A+P S Q G + RP +++ + D R
Sbjct: 608 PRPGAPPSAS--------ASPAHHASTQ--GTSHRPSLPASLNDNDLVDSDEDERAVGSL 657
Query: 233 PPNIVLEDTQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKP 292
P +P P SP+ + H GA+ A A R+T SG + +S P
Sbjct: 658 HPKGAFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPASPA--RRTPHSGAAEEDSSASAP 715
Query: 293 AQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGA 352
L+ + + L T +S PL G ++ E + AT +
Sbjct: 716 PSRLSPP----HGGSSRLLPTQPHLSS-----PLSKGGKDGE-----------DAPATNS 755
Query: 353 QGPSRVEEAEGHTE--VTEAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESLQA 410
PSR + + + + S+G +DG GD + GR A E+ + T + A
Sbjct: 756 NAPSRSTMSSSVSSHLSSRTQVSEGAEASDGESHGDGDREDGGRQA--EATAQTLRARPA 813
Query: 411 RRHHQFLEPAP 421
H L P
Sbjct: 814 SGHFHLLRHKP 824
Score = 34.7 bits (78), Expect = 0.24
Identities = 91/398 (22%), Positives = 130/398 (32%), Gaps = 80/398 (20%)
Query: 41 ALLETASPRKLSGQTRTI------ARGRSHGARSVGRSAHIQASGHLEEQTPRTLLKNIL 94
A +T R SG + A GRS S+GR +Q S + P +
Sbjct: 803 ATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQSTVPSRAHPRVP 862
Query: 95 LTAP-----ESSILMPESVVKPVPA----PQAVQPSRQESSCGSLELQLPELEPPTTLAP 145
+ S I E KP+PA SRQ S G +L+ +P
Sbjct: 863 SHSDSHPKLSSGIHGDEEDEKPLPATVVNDHVPSSSRQPISRGWEDLR---------RSP 913
Query: 146 GLLAPGRRKQRLRLSVFQQGVD---QG-----LSLSQEPQGNADASSLTRSLNLTFATPL 197
A RK+ + + G D QG S +Q+ Q + DA + S
Sbjct: 914 QRGASLHRKEPIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHS------PKA 967
Query: 198 QPQSVQRPGLARRPPARRAVDVGAFLRDLRDTSLAPPNIVLEDTQPFSQPMVGSPNVYHS 257
QP S R RPPA R+ + P + P QP H
Sbjct: 968 QPGSTDRHASPARPPAARS-----------QQHPSVPRRMTPGRAPQQQPPPPVATSQH- 1015
Query: 258 LPCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAG----EAEEVNAFALGFLST 313
H G + + AGR S P L G+P G ++ A + G L T
Sbjct: 1016 -----HPGPQSRD--AGR--SPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSRGMLPT 1066
Query: 314 SSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGS 373
+ L + E+A+ +++ V + +R +EA
Sbjct: 1067 A-----------LQNQDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEA-----AASLPKH 1110
Query: 374 QGTAEADGPGASSGDEDASGRAASPESASSTPESLQAR 411
Q G GA G AASP + S P Q+R
Sbjct: 1111 QQVESPTGAGAGGDHRSQRGHAASP-ARPSRPGGPQSR 1147
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 48.1 bits (113), Expect = 2e-05
Identities = 41/145 (28%), Positives = 55/145 (37%), Gaps = 21/145 (14%)
Query: 265 GAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVE 324
G E+ +Q G + ++ G G +K G+ GE EE G +E E
Sbjct: 787 GEEEGDQGEGEEEETEGRGEEKEEGGEVE---GGEVEE-------------GKGEREEEE 830
Query: 325 PLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGA 384
+G EE + EEEG E E +G EE EG E E EG E +G G
Sbjct: 831 EEGEGEEEEGEGEEEEGEG--EEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGE 888
Query: 385 SSGD---EDASGRAASPESASSTPE 406
G+ E+ G E E
Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEGEGE 913
Score = 46.2 bits (108), Expect = 8e-05
Identities = 43/153 (28%), Positives = 55/153 (35%), Gaps = 15/153 (9%)
Query: 268 DAEQAAGRKTQSSGPGLQKNSPGK-PAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPL 326
+ E+ G + G G ++ GK + GE EE G G GE E E
Sbjct: 834 EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG-EGEGEEEGE 892
Query: 327 HDGVEE-AEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADG---- 381
+G EE E + EEEG E E +G EE EG E E EG E +G
Sbjct: 893 GEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE 952
Query: 382 --------PGASSGDEDASGRAASPESASSTPE 406
G G+E+ G E E
Sbjct: 953 GEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985
Score = 43.5 bits (101), Expect = 5e-04
Identities = 39/130 (30%), Positives = 54/130 (41%), Gaps = 18/130 (13%)
Query: 267 EDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPL 326
E+ + G + + G G ++ G+ GE EE G GE E E
Sbjct: 905 EEEGEGEGEEEEGEGKGEEEGEEGE------GEGEEEEG-------EGEGEDGEGEGEE- 950
Query: 327 HDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEG-SQGTAEADG--PG 383
+G E E++ E EG E E G +G EE EG E E EG +G E +G G
Sbjct: 951 EEGEWEGEEE-EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG 1009
Query: 384 ASSGDEDASG 393
G+E+ G
Sbjct: 1010 EGEGEEEEEG 1019
Score = 39.7 bits (91), Expect = 0.007
Identities = 35/124 (28%), Positives = 48/124 (38%), Gaps = 23/124 (18%)
Query: 267 EDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPL 326
E E+ G + G G ++ G+ GE EE GE+E E
Sbjct: 965 EGEEEGEGEGEEGEGEGEEEEGEGE------GEEEE----------------GEEEGEEE 1002
Query: 327 HDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASS 386
+G EE E + EEE E E G +G EE EG E E E +G E +
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEERE-KEGEGEENRRNREE 1061
Query: 387 GDED 390
+E+
Sbjct: 1062 EEEE 1065
Score = 36.6 bits (83), Expect = 0.063
Identities = 37/152 (24%), Positives = 53/152 (34%), Gaps = 16/152 (10%)
Query: 267 EDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPL 326
ED E G + + G ++ G+ + GE EE GE+E
Sbjct: 942 EDGE-GEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEG------------EGEEEEGEG 988
Query: 327 HDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADG---PG 383
EE E++ EEEG E E G + E E E E EG + E +G
Sbjct: 989 EGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREK 1048
Query: 384 ASSGDEDASGRAASPESASSTPESLQARRHHQ 415
G+E+ R E E+ + Q
Sbjct: 1049 EGEGEENRRNREEEEEEEGKYQETGEEENERQ 1080
Score = 36.2 bits (82), Expect = 0.082
Identities = 34/143 (23%), Positives = 54/143 (37%), Gaps = 13/143 (9%)
Query: 267 EDAEQAAGRKTQSSGPGLQKNSPGKPAQFLA---------GEAEEVNAFALGFLSTSSGV 317
+D E+ G K + G + PG+ + LA GE +E G +
Sbjct: 670 QDEEREKGEKDKGRG---EMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQE 726
Query: 318 SGEDEVEPLHDGVEE-AEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGT 376
E E +G EE +++ EEE + E G + E+ EG + E G +
Sbjct: 727 MEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEK 786
Query: 377 AEADGPGASSGDEDASGRAASPE 399
E +G +E+ GR E
Sbjct: 787 GEEEGDQGEGEEEETEGRGEEKE 809
Score = 36.2 bits (82), Expect = 0.082
Identities = 35/127 (27%), Positives = 47/127 (37%), Gaps = 27/127 (21%)
Query: 268 DAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPLH 327
+ E+ G + + G ++ GK + GE E G GE E E
Sbjct: 760 EGEEVEGEREKEEGERKKEERAGKEEK---GEEE--------------GDQGEGEEEETE 802
Query: 328 DGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEAD-----GP 382
EE E+ E EG V E +G EE EG E E EG + E + G
Sbjct: 803 GRGEEKEEGGEVEGGEVEE-----GKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGK 857
Query: 383 GASSGDE 389
G G+E
Sbjct: 858 GEEEGEE 864
Score = 35.0 bits (79), Expect = 0.18
Identities = 22/76 (28%), Positives = 27/76 (35%)
Query: 331 EEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDED 390
EE E+K EE + E G QG EE EG E E G E + +E+
Sbjct: 771 EEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEE 830
Query: 391 ASGRAASPESASSTPE 406
G E E
Sbjct: 831 EEGEGEEEEGEGEEEE 846
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 44.3 bits (103), Expect = 3e-04
Identities = 124/480 (25%), Positives = 164/480 (34%), Gaps = 70/480 (14%)
Query: 2 ADHNPDSDSTPRTLLRRVLDTA--DPRTPRRPRSARAGARRALL--ETASPRKLSGQTRT 57
A + S +TP + R +A PR P P + +AL + PRK +
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL- 296
Query: 58 IARGRSHGARSVGRSAHIQASGHLEEQTPRTL------------LKNILLTAPESSILMP 105
G S A S L+ Q P TL L L AP S P
Sbjct: 297 -------GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP 349
Query: 106 ESVVKPVPAPQAVQPSRQESSCGSLELQLP-ELEPPTTLAPGLLAPGRRKQRLRLSVFQ- 163
++ +P+P A PS+ +S GS LQ P L+P P + L L Q
Sbjct: 350 S--LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407
Query: 164 ---QGVDQGLSLSQEPQGNADASSLTRSLNLTFATPLQPQSVQRPGLARRPPARRAVDVG 220
LS P A + L F+ P P VQ P PPA V
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAP---FSPPASPPVSPS 463
Query: 221 AFLRDLRDTSLAPPNIVLEDTQPFSQPMVGS----PNVYHSLPCTPHTGAEDAEQAAGRK 276
A SLA P + + + P S PM S P L P A+ QA
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA---P 520
Query: 277 TQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKK 336
+ P LQ P PA F G+A S S+ + + PL +A
Sbjct: 521 PALATPPLQA-LPSPPASF-PGQAP---------FSPSASL----PMSPLATPPPQAPPV 565
Query: 337 MEEEGVSV--SEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGAS-SGDEDASG 393
+ + V S + Q P R T V+ + A P S S SG
Sbjct: 566 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 625
Query: 394 --RAASPESASSTPESLQARRHHQFLEPAPAPGAAVLSSEPAEPLLVRHPPRPRTTGPRP 451
A SA+STPE L+ + P GAA +S P + L P + GP P
Sbjct: 626 PDLAGHSSSATSTPEELRG------YDSGPEGGAA--ASPPPDAELAACHPAAWSRGPAP 677
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 44.3 bits (103), Expect = 3e-04
Identities = 117/461 (25%), Positives = 158/461 (34%), Gaps = 61/461 (13%)
Query: 22 TADPRTPRRPRSARAG-----ARRALLETASPRKLSGQTRTIARG--RSHGARSVGRSAH 74
T +P R R + G A R+L +A+P ++ ARG R+ S +
Sbjct: 208 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 267
Query: 75 IQASGHLEEQTPRTLLKNILLTAPESSILMPESVVKP----------VPAPQAVQPSRQE 124
+QA + PR L S + P P +P+P A PS+
Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327
Query: 125 SSCGSLELQLP-ELEPPTTLAPGLLAPGRRKQRLRLSVFQ----QGVDQGLSLSQEPQGN 179
+S GS LQ P L+P P + L L Q LS P
Sbjct: 328 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 387
Query: 180 ADASSLTRSLNLTFATPLQPQSVQRPGLARRPPARRAVDVGAFLRDLRDTSLAPPNIVLE 239
A + L F+ P P VQ P PPA V A SLA P + +
Sbjct: 388 APNALAVHLLQAPFSPPPSP-PVQAP---FSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443
Query: 240 DTQPFSQPMVGS----PNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQF 295
+ P S PM S P L P A+ QA + P LQ P PA F
Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA---PPALATPPLQA-LPSPPASF 499
Query: 296 LAGEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSV--SEMEATGAQ 353
G+A S S+ + + PL +A + + V S + Q
Sbjct: 500 -PGQAP---------FSPSASL----PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 545
Query: 354 GPSRVEEAEGHTEVTEAEGSQGTAEADGPGAS-SGDEDASG--RAASPESASSTPESLQA 410
P R T V+ + A P S S SG A SA+STPE L+
Sbjct: 546 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 605
Query: 411 RRHHQFLEPAPAPGAAVLSSEPAEPLLVRHPPRPRTTGPRP 451
+ P GAA +S P + L P + GP P
Sbjct: 606 ------YDSGPEGGAA--ASPPPDAELAACHPAAWSRGPAP 638
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 44.3 bits (103), Expect = 3e-04
Identities = 51/193 (26%), Positives = 77/193 (39%), Gaps = 16/193 (8%)
Query: 299 EAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRV 358
E EEV A +T+ V E+ + +G EE E+ E+EG + E G++
Sbjct: 502 EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE--EDEGAKSDQAEEGGSEKEGSS 559
Query: 359 EEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESLQARRHHQFLE 418
E+ EG E E E AEA+G A + +E + +T E L A + E
Sbjct: 560 EKEEGEQEEGETE-----AEAEGEEAEAKEEK---KVEEKSEEVATKEELVADAKVEKPE 611
Query: 419 PAPAPGAAVLSSEPAEPLLVRHPPRPRTTGPRPRQDPHKAGLSHYVKL------FSFYAK 472
A +P E + + + P + P P+ + G S K S +K
Sbjct: 612 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSK 671
Query: 473 MPMERKALEMVEK 485
P+E KA V K
Sbjct: 672 SPVEEKAKSPVPK 684
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 44.3 bits (103), Expect = 3e-04
Identities = 51/193 (26%), Positives = 77/193 (39%), Gaps = 16/193 (8%)
Query: 299 EAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRV 358
E EEV A +T+ V E+ + +G EE E+ E+EG + E G++
Sbjct: 126 EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE--EDEGAKSDQAEEGGSEKEGSS 183
Query: 359 EEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESLQARRHHQFLE 418
E+ EG E E E AEA+G A + +E + +T E L A + E
Sbjct: 184 EKEEGEQEEGETE-----AEAEGEEAEAKEEK---KVEEKSEEVATKEELVADAKVEKPE 235
Query: 419 PAPAPGAAVLSSEPAEPLLVRHPPRPRTTGPRPRQDPHKAGLSHYVKL------FSFYAK 472
A +P E + + + P + P P+ + G S K S +K
Sbjct: 236 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSK 295
Query: 473 MPMERKALEMVEK 485
P+E KA V K
Sbjct: 296 SPVEEKAKSPVPK 308
>gi|4885379 histone cluster 1, H1e [Homo sapiens]
Length = 219
Score = 43.5 bits (101), Expect = 5e-04
Identities = 42/172 (24%), Positives = 72/172 (41%), Gaps = 15/172 (8%)
Query: 259 PCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEA----EEVNAFALGFLSTS 314
P P A + +K + S ++ + G P L +A +E + +L L +
Sbjct: 6 PAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLAALKKA 65
Query: 315 SGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQ 374
+G D VE + ++ K + +G V + + TGA G ++ + E
Sbjct: 66 LAAAGYD-VEKNNSRIKLGLKSLVSKGTLV-QTKGTGASGSFKLNKKAASGEAKPKAKKA 123
Query: 375 GTAEADGP-GASSGDEDASGRAASPESASSTPESLQARRHHQFLEPAPAPGA 425
G A+A P GA+ + A+G A +SA TP+ + +PA A GA
Sbjct: 124 GAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAK--------KPAAAAGA 167
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 43.1 bits (100), Expect = 7e-04
Identities = 48/210 (22%), Positives = 80/210 (38%), Gaps = 20/210 (9%)
Query: 262 PHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAG-EAEEVNAFAL---GFLSTSSGV 317
P T AE+ E ++ ++ PG P K + + + +FAL G ++
Sbjct: 914 PSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESS 973
Query: 318 SGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTA 377
S +DE D E+ E + EE V ++ E + G ++ + + +
Sbjct: 974 SEKDE----EDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDS 1029
Query: 378 EADGPGASSGDEDASGRAASPESASSTPESLQARRHHQFLEPAPAPGAAVLSSEPAE--- 434
+D +SS +S ++S S+SS+ + + PA P A S P E
Sbjct: 1030 TSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSA---SPPPREVPV 1086
Query: 435 --PLLVRHPPRPRTTG----PRPRQDPHKA 458
P V P R G P P Q+ A
Sbjct: 1087 PTPAPVEVPVPERVAGSPVTPLPEQEASPA 1116
Score = 34.3 bits (77), Expect = 0.31
Identities = 60/234 (25%), Positives = 92/234 (39%), Gaps = 50/234 (21%)
Query: 6 PDSDSTPRTLLRRV----LDTAD-----PRTPRRPRSARAGARRALLETASPRK------ 50
P S PR + R + LD A P R +RAG R L E
Sbjct: 1194 PASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDL 1253
Query: 51 --LSGQTRTIARGRSHGARSVGRSAHIQASGHLEEQTPRTLLKNILL----------TAP 98
L+ T AR +V S + S E + PR LL +ILL T P
Sbjct: 1254 AVLADLALTPARRGLPALPAVEDSEATETSD--EAERPRPLLSHILLEHNYALAVKPTPP 1311
Query: 99 ESSILMPESVVKPVPAPQAVQPSRQESSCGSLELQLPELEPPTTLAPGLLAPGRRKQRLR 158
++ PE PVPAP A+ S + + E+ + E E P ++ Q+ R
Sbjct: 1312 APALRPPE----PVPAPAALFSSPADEVLEAPEVVVAEAEEPKP---------QQLQQQR 1358
Query: 159 LSVFQQGVDQGLSLSQEPQGNADASSLTRSLNLTFATPLQPQSVQRPGLARRPP 212
++G ++G +E + ++D+SS + L+ +S++ RRPP
Sbjct: 1359 EEGEEEGEEEG---EEEEEESSDSSSSSDG-----EGALRRRSLRSHARRRRPP 1404
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/178 (23%), Positives = 68/178 (38%), Gaps = 13/178 (7%)
Query: 273 AGRKTQSSGPGLQKNSPGKPAQFLAGEAEE---VNAFALGFLSTSSGVSGEDEVEPLHDG 329
AG ++ PG + + Q +A E+ + +A+ FL S +E++ +
Sbjct: 2279 AGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQ 2338
Query: 330 VEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDE 389
VE A K +++ V + +GP +E+ T S+ + PG + E
Sbjct: 2339 VEAARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPG-TRVSE 2397
Query: 390 DASGRAASPESASSTPESLQARRHHQFLEPAPAPGAAVLSSEPAEPLLVRHPPRPRTT 447
G A + A+ TP HQ P + PA + R PRPR T
Sbjct: 2398 RLRGARAETQGANHTP----VISAHQTRSTTTPPRCS-----PARERVPRPAPRPRPT 2446
Score = 33.9 bits (76), Expect = 0.41
Identities = 65/232 (28%), Positives = 82/232 (35%), Gaps = 30/232 (12%)
Query: 63 SHGARSVGRSAHIQASGHLEEQTPRTLLKNILLTAPESSILMPESVVKPVPAPQAVQPSR 122
S GA V S+ TP T L + + +L P S +PAP PS
Sbjct: 1615 SPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAP---VPSP 1671
Query: 123 QESSCGSLELQLPELEPPTTLAPGLLAPGRRKQRLRLSVFQ-QGVDQGLSLSQEPQGNAD 181
S + L L PT L Q L L QG +LS P
Sbjct: 1672 LPSPASTQTLALAPALAPT------LGGSSPSQTLSLGTGNPQGPFPTQTLSLTP----- 1720
Query: 182 ASSL----TRSLNLTFATPLQPQSVQRPGLARRPPARRAVDVG---AFLRDLRDTS---- 230
ASSL ++L+L PL P Q LA PP A VG A L S
Sbjct: 1721 ASSLVPTPAQTLSLAPGPPLGP--TQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSAS 1778
Query: 231 -LAPPNIVLEDTQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSG 281
LAP ++ P P +G P +L P + A QA+ +SG
Sbjct: 1779 LLAPASVQTLTLSPAPVPTLG-PAAAQTLALAPASTQSPASQASSLVVSASG 1829
>gi|45120115 hypothetical protein LOC56905 [Homo sapiens]
Length = 1047
Score = 40.4 bits (93), Expect = 0.004
Identities = 39/149 (26%), Positives = 58/149 (38%), Gaps = 18/149 (12%)
Query: 309 GFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVT 368
G L G SG +PL ++E E + +S + T P + + H + T
Sbjct: 550 GTLPAQEGPSGS---KPLRGSLKE------EVALDLSVRKPTAEASPVKASRSVEHAKPT 600
Query: 369 EAEG--SQGTAEADGPGASSGDEDASGRAASPESASSTPES------LQARRHHQFLEPA 420
A G +D PG D +A G P + + P + R + L PA
Sbjct: 601 AAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPA 660
Query: 421 PAPGAAVLSSEPAEPLLVRHPPRPRTTGP 449
P P A V S+ + P + P P T+GP
Sbjct: 661 PLPAAVVPSTPTSAPAPTQPAPTP-TSGP 688
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 40.4 bits (93), Expect = 0.004
Identities = 53/236 (22%), Positives = 83/236 (35%), Gaps = 21/236 (8%)
Query: 239 EDTQPFSQPMVGSPNVYHSLPCTPH----TGAEDAEQAAGRKTQ-SSGPGLQKNSPGKPA 293
E+T SQ M G S P T A + ++A ++ + SG N KP
Sbjct: 120 EETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPE 179
Query: 294 QFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQ 353
E E+ + +G E EP +E K ++ V E +A +
Sbjct: 180 PKATVEEEDAKTAS----QEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKE 235
Query: 354 GPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGD-------EDASGRAASPESASSTPE 406
+ E G E +A+ AE PG+ S + E G P S PE
Sbjct: 236 PDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWPE 295
Query: 407 SLQARRHHQFLE----PAPAPGAAVLSSEPAEPLLV-RHPPRPRTTGPRPRQDPHK 457
S H+ + A G S+ + P V + PP ++G + + P +
Sbjct: 296 SPTGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSPPESPSSGEKKEKAPER 351
>gi|221139926 NHS-like 1 [Homo sapiens]
Length = 1606
Score = 40.0 bits (92), Expect = 0.006
Identities = 93/400 (23%), Positives = 139/400 (34%), Gaps = 91/400 (22%)
Query: 98 PESSILMPESVVKPVPAPQAVQPSRQESSCGSLELQ-LPELEPPTT------LAPGLLAP 150
P S ++P+S V +P P + PS + L+ + + + PP T + G L P
Sbjct: 995 PALSPILPDSPVS-LPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRP 1053
Query: 151 GRRKQRLRLSVFQQGVDQGLSLSQ----EPQGNADASSLTRSLNLTFATPLQPQSVQRPG 206
K+ + L + Q A+A+ L+ TP+ PQ +P
Sbjct: 1054 PSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPS 1113
Query: 207 LARRPPARRAVDVGAFLRDLRDTSLAPPNIVLEDTQPFS------QPMVGSPNVYHSL-- 258
AFL+ T N + ++QP S P S H
Sbjct: 1114 --------------AFLKSRNST-----NEMESESQPASVTSSLPTPAKSSSQGDHGSAA 1154
Query: 259 ----PCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPG--------KPAQFLA--------- 297
P + GA A +A R + S+ P L +SP KP FL
Sbjct: 1155 ERGGPVSRSPGAPSAGEAEARPSPSTTP-LPDSSPSRKPPPISKKPKLFLVVPPPQKDFA 1213
Query: 298 -GEAEEVNAFALGFLSTSSGVSGE-DEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGP 355
AE V+ S ++G G E +A G SV E A G+ P
Sbjct: 1214 VEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSP 1273
Query: 356 SRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRA--ASPESASSTPESLQARRH 413
SRV E + + + + S + + P +S D G + + + A+ PE+
Sbjct: 1274 SRV---EANVPMVQPDVSPAPKQEE-PAENSADTGGDGESCLSQQDGAAGVPET------ 1323
Query: 414 HQFLEPAPAPGAAVLSSEPAEPLL------VRHPPRPRTT 447
AA SSE + L V P RPRTT
Sbjct: 1324 ----------NAAGSSSEACDFLKEDGNDEVMTPSRPRTT 1353
>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
Length = 922
Score = 40.0 bits (92), Expect = 0.006
Identities = 91/381 (23%), Positives = 135/381 (35%), Gaps = 54/381 (14%)
Query: 94 LLTAPESSILMPESVVKPVPAPQAVQPSRQESSCGSLELQLPELEPPTTLAPGLLAPGRR 153
L P SS P + P AP A P R+ + + + P + P+ AP + AP R+
Sbjct: 422 LPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRK 481
Query: 154 KQRLRLSVFQQGV------------DQGLSLSQEPQGNADASSLTRSLNLTFATPLQ--- 198
S + + S+ PQ A + + + +L P Q
Sbjct: 482 ASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQ-KAVSPTAPKKKSLLLPAPSQKAL 540
Query: 199 PQSVQRPGLARRPPARRAVDVGAFLRDLRDTSLAPPNIVLEDTQPFSQPMVGSPNVYHSL 258
P S +A PPA R G F D+ T + P VLE +Q +P P V
Sbjct: 541 PTSPTEYQMALSPPASRGKLPGDF--DVLPTGI-PGRAVLERSQSGGKP---EPVV---- 590
Query: 259 PCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFAL---GFLSTSS 315
T T D + + P K L + +EV A G L +
Sbjct: 591 --TVRTQETDVVEMTTQAKSPESPFTVTKKESK--DILISQTKEVTLEAFRGQGKLEDWA 646
Query: 316 GVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQG 375
+ +E P GV E + + V E+ +GPS+ E
Sbjct: 647 HWAKLEERSPDLPGVRSKELEQRKRWVKAKEL---AVEGPSQEHSRPFSVEALTLTKLMI 703
Query: 376 TAEA-DGPGASSGDEDASGRAASPE-SASSTPESLQARRHHQFLEPAPAPGAAVLSSEPA 433
TA + + P S+ S A+P+ SA+S S+ +R PG LS
Sbjct: 704 TANSKEQPSKSALVSLPSWLLATPQASATSMMASVPSR-----------PGQ--LSLLEG 750
Query: 434 EPLLVRHPPRPRT---TGPRP 451
+P++VR P T G RP
Sbjct: 751 KPVVVREQPESHTWVKEGKRP 771
>gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
Length = 931
Score = 39.7 bits (91), Expect = 0.007
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 26/112 (23%)
Query: 330 VEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQ-----GTAEADGPGA 384
V++ + E E V ++ G QGPS ++ T +T++ G+ AD PG
Sbjct: 623 VKQEALQPEPEPVPAPQL-LLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGL 681
Query: 385 SSGDEDASGRAASPESASSTPESLQARRHHQFLEPAPAPGAAVLSSEPAEPL 436
SSG SP+ SS P S PAPAP A + P +PL
Sbjct: 682 SSG---------SPQQPSSQPGS-----------PAPAPSAQMDLEHPLQPL 713
>gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 1941
Score = 39.7 bits (91), Expect = 0.007
Identities = 49/207 (23%), Positives = 75/207 (36%), Gaps = 24/207 (11%)
Query: 229 TSLAPPNIVLEDTQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNS 288
T LA +V QP Q + G+P + P P + ++ GR+ + PG N
Sbjct: 573 THLASYGVVQLFDQPHPQRLAGAPALAPEPPLIPKLLVQTIQETTGREDFTENPGQLPNG 632
Query: 289 PGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEME 348
G+P EA A + V+GED++E + ++ S+S
Sbjct: 633 VGRPVL----EATPCEA----SWTRDRPVAGEDDLEQATEALD-----------SISLAG 673
Query: 349 ATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESL 408
G Q S + + G + A S+ GA G E GR PE +
Sbjct: 674 KAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPG-EGEEGRILLPEGFNPMQALE 732
Query: 409 QARRHHQFLEPAPAPGAAVLSSEPAEP 435
+ + FL A G L P +P
Sbjct: 733 ELEKTGNFL----AKGLGGLLEVPEQP 755
>gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 2240
Score = 39.7 bits (91), Expect = 0.007
Identities = 49/207 (23%), Positives = 75/207 (36%), Gaps = 24/207 (11%)
Query: 229 TSLAPPNIVLEDTQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNS 288
T LA +V QP Q + G+P + P P + ++ GR+ + PG N
Sbjct: 872 THLASYGVVQLFDQPHPQRLAGAPALAPEPPLIPKLLVQTIQETTGREDFTENPGQLPNG 931
Query: 289 PGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEME 348
G+P EA A + V+GED++E + ++ S+S
Sbjct: 932 VGRPVL----EATPCEA----SWTRDRPVAGEDDLEQATEALD-----------SISLAG 972
Query: 349 ATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESL 408
G Q S + + G + A S+ GA G E GR PE +
Sbjct: 973 KAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPG-EGEEGRILLPEGFNPMQALE 1031
Query: 409 QARRHHQFLEPAPAPGAAVLSSEPAEP 435
+ + FL A G L P +P
Sbjct: 1032 ELEKTGNFL----AKGLGGLLEVPEQP 1054
>gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 1941
Score = 39.7 bits (91), Expect = 0.007
Identities = 49/207 (23%), Positives = 75/207 (36%), Gaps = 24/207 (11%)
Query: 229 TSLAPPNIVLEDTQPFSQPMVGSPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNS 288
T LA +V QP Q + G+P + P P + ++ GR+ + PG N
Sbjct: 573 THLASYGVVQLFDQPHPQRLAGAPALAPEPPLIPKLLVQTIQETTGREDFTENPGQLPNG 632
Query: 289 PGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEME 348
G+P EA A + V+GED++E + ++ S+S
Sbjct: 633 VGRPVL----EATPCEA----SWTRDRPVAGEDDLEQATEALD-----------SISLAG 673
Query: 349 ATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESL 408
G Q S + + G + A S+ GA G E GR PE +
Sbjct: 674 KAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPG-EGEEGRILLPEGFNPMQALE 732
Query: 409 QARRHHQFLEPAPAPGAAVLSSEPAEP 435
+ + FL A G L P +P
Sbjct: 733 ELEKTGNFL----AKGLGGLLEVPEQP 755
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 39.7 bits (91), Expect = 0.007
Identities = 38/184 (20%), Positives = 68/184 (36%), Gaps = 8/184 (4%)
Query: 263 HTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDE 322
+T ED+E+ + GP +Q G+ ++V + + +DE
Sbjct: 1903 YTPMEDSEETSQSLQIDLGPLQSDQQTTTSSQDGQGKGDDVIV-----IDSDDEEEDDDE 1957
Query: 323 VEPLHDGVEEAEKKME--EEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEAD 380
+ H+ EE E+ + E+ + + +G + +G+ E +AEG GT
Sbjct: 1958 NDGEHEDYEEDEEDDDDDEDDTGMGDEGEDSNEGTGSADGNDGY-EADDAEGGDGTDPGT 2016
Query: 381 GPGASSGDEDASGRAASPESASSTPESLQARRHHQFLEPAPAPGAAVLSSEPAEPLLVRH 440
S G + + RAA +++ Q + P +A P P R
Sbjct: 2017 ETEESMGGGEGNHRAADSQNSGEGNTGAAESSFSQEVSREQQPSSASERQAPRAPQSPRR 2076
Query: 441 PPRP 444
PP P
Sbjct: 2077 PPHP 2080
>gi|145386517 phostensin [Homo sapiens]
Length = 613
Score = 39.7 bits (91), Expect = 0.007
Identities = 52/214 (24%), Positives = 78/214 (36%), Gaps = 41/214 (19%)
Query: 267 EDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPL 326
+D + GRK + PG+ + ++ L EA+ ++S+GV ++ P+
Sbjct: 270 QDYSEECGRKEEWPVPGVAPKETAELSETLTREAQG---------NSSAGVEAAEQ-RPV 319
Query: 327 HDGVEEAEKKMEEEGVSVSEMEA---------TGAQGPSRVEEAEGHTEVTEAEGSQGTA 377
DG E K E +++ +A Q P E AE E E +G A
Sbjct: 320 EDG-ERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEA 378
Query: 378 EADGPGASSGDEDASGRAAS------PESASSTPESLQARRHHQFLEPAPAPGAAVLSSE 431
E + GA A S PE A + Q + P PAP +
Sbjct: 379 EKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLS------ 432
Query: 432 PAEPLLVRHPPRPRTTGPRPRQDPHKAGLSHYVK 465
PP P T P+P DP + L + VK
Sbjct: 433 ---------PPPPAPTAPQPPGDPLMSRLFYGVK 457
Score = 30.8 bits (68), Expect = 3.4
Identities = 40/128 (31%), Positives = 51/128 (39%), Gaps = 13/128 (10%)
Query: 17 RRVLDTADPRTPRRPRSARA---GARRALLETASPRKLSGQTRTIARGRSHGARSVGRSA 73
RR + A P TP P + A GA + TA + G ++R S A+
Sbjct: 477 RRSVPPATPATPTSPATVDAAVPGAGKKRYPTAEEILVLGGYLRLSR--SCLAKGSPERH 534
Query: 74 HIQASGHLEEQTPRTLLKNILLTAPESSILM---PESVVKPVPAPQAVQPSRQESSCGSL 130
H Q E T L+ ESS+L PE V P P A QP +E L
Sbjct: 535 HKQLKISFSE----TALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELL 590
Query: 131 ELQLPELE 138
LQ PEL+
Sbjct: 591 LLQ-PELQ 597
>gi|199559805 phostensin [Homo sapiens]
Length = 613
Score = 39.7 bits (91), Expect = 0.007
Identities = 52/214 (24%), Positives = 78/214 (36%), Gaps = 41/214 (19%)
Query: 267 EDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPL 326
+D + GRK + PG+ + ++ L EA+ ++S+GV ++ P+
Sbjct: 270 QDYSEECGRKEEWPVPGVAPKETAELSETLTREAQG---------NSSAGVEAAEQ-RPV 319
Query: 327 HDGVEEAEKKMEEEGVSVSEMEA---------TGAQGPSRVEEAEGHTEVTEAEGSQGTA 377
DG E K E +++ +A Q P E AE E E +G A
Sbjct: 320 EDG-ERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEA 378
Query: 378 EADGPGASSGDEDASGRAAS------PESASSTPESLQARRHHQFLEPAPAPGAAVLSSE 431
E + GA A S PE A + Q + P PAP +
Sbjct: 379 EKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLS------ 432
Query: 432 PAEPLLVRHPPRPRTTGPRPRQDPHKAGLSHYVK 465
PP P T P+P DP + L + VK
Sbjct: 433 ---------PPPPAPTAPQPPGDPLMSRLFYGVK 457
Score = 30.8 bits (68), Expect = 3.4
Identities = 40/128 (31%), Positives = 51/128 (39%), Gaps = 13/128 (10%)
Query: 17 RRVLDTADPRTPRRPRSARA---GARRALLETASPRKLSGQTRTIARGRSHGARSVGRSA 73
RR + A P TP P + A GA + TA + G ++R S A+
Sbjct: 477 RRSVPPATPATPTSPATVDAAVPGAGKKRYPTAEEILVLGGYLRLSR--SCLAKGSPERH 534
Query: 74 HIQASGHLEEQTPRTLLKNILLTAPESSILM---PESVVKPVPAPQAVQPSRQESSCGSL 130
H Q E T L+ ESS+L PE V P P A QP +E L
Sbjct: 535 HKQLKISFSE----TALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELL 590
Query: 131 ELQLPELE 138
LQ PEL+
Sbjct: 591 LLQ-PELQ 597
>gi|61966919 hypothetical protein LOC442444 [Homo sapiens]
Length = 1035
Score = 39.3 bits (90), Expect = 0.010
Identities = 101/424 (23%), Positives = 140/424 (33%), Gaps = 62/424 (14%)
Query: 80 HLEEQTPRTLLKNILLTAPESSILMPESVVKPVPAPQAVQPSRQESSCGSLELQLPELEP 139
HL + P+T + ++ L PE+ + S + P P + V R E + P EP
Sbjct: 449 HLRPEPPKTRVSSLHLEPPETGV----SHLCPEPPEKDVSHLRPEPPDTGVSHLCP--EP 502
Query: 140 PTTLAPGLLAPGRRKQRLRLSVFQQGVDQGLSLSQEPQGNADASSLTRSLNLTFATPLQP 199
P T R LR + GV L EP SSL ++ + + L+P
Sbjct: 503 PKT----------RVSHLRPEPSETGVSH---LRPEPP-KILVSSLHQAPPESSVSHLRP 548
Query: 200 QSVQR--PGLARRPPARRAVDVGAFLRDLRDTSLAP-PNIVLEDTQPFSQPMVG------ 250
+ + L PP R + D + L P P + P P G
Sbjct: 549 EPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCP 608
Query: 251 ---SPNVYHSLPCTPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFA 307
V H P P TG + S L+ P L E + +
Sbjct: 609 EPPETRVSHLRPEPPETGVSHLRPEPPKTRMYS---LRPEPPNTGVSHLCPEPPKTRVSS 665
Query: 308 LGFLSTSSGVSGEDEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEV 367
L +GVS EP V + E GVS E P + + H E
Sbjct: 666 LPPEPPETGVSHLCP-EPPETRVSHLRPEPPETGVSRLHPE------PPKTRVSSLHAEP 718
Query: 368 TEAEGSQGTAEADGPGASSGDEDASGRAASPESASSTPESLQARRHHQFLEPAPAPGAAV 427
E+ S E G S P +S PE L+ R H EP P G +
Sbjct: 719 PESRVSHLCPEPPETGVS----HLRPEPPKPRVSSLRPEPLETRVSHLRPEP-PETGVSH 773
Query: 428 LSSEPAEP---LLVRHPPRPRTTG------PRPRQ------DPHKAGLSHYVKLFSFYAK 472
L E +P L PP+ R P+ + +P K G SH +LF
Sbjct: 774 LHPELPKPRVSSLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEPTKTGASHLKELFQEGTS 833
Query: 473 MPME 476
ME
Sbjct: 834 STME 837
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 38.9 bits (89), Expect = 0.013
Identities = 99/399 (24%), Positives = 129/399 (32%), Gaps = 79/399 (19%)
Query: 97 APESSILMPESVVKPVPAPQAVQPSRQESSCGSLELQLPELEPPTTLAPGLLAPGRRKQR 156
AP PE+ ++ PAP AV SR APG L P +
Sbjct: 1069 APTIGEPAPETSLERAPAPSAVVSSRNGGE----------------TAPGPLGPAPKNGT 1112
Query: 157 LRLSVFQQGVDQGLSLSQEPQGNADASSLTRSLNLTFATPLQPQSVQRPGLARRPPARRA 216
L ++ + G + G D S R+ T P PG
Sbjct: 1113 LEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAP-----GGGPG--------SG 1159
Query: 217 VDVGAFLRDLRDTSLAPPNIVLEDTQPFSQPMVGSPNVYHSLPCTPHTGAEDA-EQAAGR 275
VD A D PP + P +QP P + P G A + AG
Sbjct: 1160 VDAKAGWVDNTRPQPPPPPL---PPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGG 1216
Query: 276 KTQSSG----PGLQKNSPGKPAQFL-----AGEAEEVNAFALGFLS------TSSGVSGE 320
T SG P ++ P P FL G +E++ A L LS T + G
Sbjct: 1217 DTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKA-RLSRLSLALPPLTLTPFPGP 1275
Query: 321 DEVEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSR---VEEAEGHTEVTEAEGSQGTA 377
P +G + G + E GA GP+ +E E E EA A
Sbjct: 1276 GPRRPPWEGA--------DAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAA 1327
Query: 378 EADGPG----------ASSGDEDAS----GRAASPESASSTPESLQARRHHQFLEPAPAP 423
GPG SS D DA+ G SP A PE + R + +
Sbjct: 1328 GPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGADE-PEDSELERKRKMVSFHGDV 1386
Query: 424 GAAVLSSE-PAEPLLVRHPPRPRT---TGPRPRQDPHKA 458
+ E P L V+ PP T T P P PH A
Sbjct: 1387 TVYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPA 1425
Score = 32.3 bits (72), Expect = 1.2
Identities = 40/140 (28%), Positives = 48/140 (34%), Gaps = 13/140 (9%)
Query: 330 VEEAEKKMEEEGVSVSEMEATGAQGPSR-------VEEAEGHTEVTEAEGSQGTAEADGP 382
VEE E+ EEEG S E ++ GPSR + EG E A G
Sbjct: 667 VEEEEE--EEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGH 724
Query: 383 ---GASSGDEDASGRAASPESASSTPESLQARRHHQFLEPAPAPGAAVLSSEPAEPLLVR 439
G ED S A S + P + A +FL+P A P
Sbjct: 725 PALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPP 784
Query: 440 HPPRPRT-TGPRPRQDPHKA 458
PP PR P DP A
Sbjct: 785 PPPPPRAPADPAASPDPPSA 804
>gi|55749431 transcription elongation factor A (SII)-like 3 [Homo
sapiens]
Length = 200
Score = 38.9 bits (89), Expect = 0.013
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 2/84 (2%)
Query: 320 EDEVEPLHDGVEEAEKKMEEEGVSVSE--MEATGAQGPSRVEEAEGHTEVTEAEGSQGTA 377
EDEVEP +G + E+K + EG + E E G G E EG E +G
Sbjct: 19 EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKP 78
Query: 378 EADGPGASSGDEDASGRAASPESA 401
+ +G AS ++ RAA A
Sbjct: 79 QGEGKPASQAKPESQPRAAEKRPA 102
>gi|14249718 transcription elongation factor A (SII)-like 3 [Homo
sapiens]
Length = 200
Score = 38.9 bits (89), Expect = 0.013
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 2/84 (2%)
Query: 320 EDEVEPLHDGVEEAEKKMEEEGVSVSE--MEATGAQGPSRVEEAEGHTEVTEAEGSQGTA 377
EDEVEP +G + E+K + EG + E E G G E EG E +G
Sbjct: 19 EDEVEPDDEGKSDEEEKPDVEGKTECEGKREDEGEPGDEGQLEDEGSQEKQGRSEGEGKP 78
Query: 378 EADGPGASSGDEDASGRAASPESA 401
+ +G AS ++ RAA A
Sbjct: 79 QGEGKPASQAKPESQPRAAEKRPA 102
>gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]
Length = 498
Score = 38.5 bits (88), Expect = 0.017
Identities = 40/172 (23%), Positives = 59/172 (34%), Gaps = 26/172 (15%)
Query: 275 RKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAE 334
RK ++ + K KP +A A E A+ E + + + V +
Sbjct: 267 RKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVK----------ESSIRSVQETVLPIK 316
Query: 335 KKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGR 394
K+ E VS+ E S + E G +G PG S + GR
Sbjct: 317 KRKTRETVSIEVKEVVKPLLVSTLGEKSG----------KGLKTCKSPGRKSKESSPKGR 366
Query: 395 AASPESASSTPESLQARRHHQFLE--PAPAPGAAVLSSEPAEPLLVRHPPRP 444
++S +S+P + HH E AP P L P EP P P
Sbjct: 367 SSS----ASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSP 414
>gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]
Length = 486
Score = 38.5 bits (88), Expect = 0.017
Identities = 40/172 (23%), Positives = 59/172 (34%), Gaps = 26/172 (15%)
Query: 275 RKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDEVEPLHDGVEEAE 334
RK ++ + K KP +A A E A+ E + + + V +
Sbjct: 255 RKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVK----------ESSIRSVQETVLPIK 304
Query: 335 KKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGR 394
K+ E VS+ E S + E G +G PG S + GR
Sbjct: 305 KRKTRETVSIEVKEVVKPLLVSTLGEKSG----------KGLKTCKSPGRKSKESSPKGR 354
Query: 395 AASPESASSTPESLQARRHHQFLE--PAPAPGAAVLSSEPAEPLLVRHPPRP 444
++S +S+P + HH E AP P L P EP P P
Sbjct: 355 SSS----ASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSP 402
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,459,528
Number of Sequences: 37866
Number of extensions: 1412520
Number of successful extensions: 8997
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 512
Number of HSP's that attempted gapping in prelim test: 7505
Number of HSP's gapped (non-prelim): 1854
length of query: 561
length of database: 18,247,518
effective HSP length: 107
effective length of query: 454
effective length of database: 14,195,856
effective search space: 6444918624
effective search space used: 6444918624
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.