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Search of human proteins with 42544179
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
(898 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ... 1819 0.0
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [... 1819 0.0
gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ... 1629 0.0
gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ... 1616 0.0
gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ... 1554 0.0
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 89 1e-17
gi|38788274 bromodomain PHD finger transcription factor isoform ... 89 1e-17
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 89 2e-17
gi|221139761 zinc finger protein 853 [Homo sapiens] 85 3e-16
gi|148612879 polyhomeotic like 3 [Homo sapiens] 83 1e-15
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 82 3e-15
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 81 4e-15
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 81 4e-15
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 78 4e-14
gi|33286444 mastermind-like 2 [Homo sapiens] 74 5e-13
gi|38788260 bromodomain PHD finger transcription factor isoform ... 74 8e-13
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 73 1e-12
gi|110349719 titin isoform N2-A [Homo sapiens] 72 2e-12
gi|146134388 YLP motif containing 1 [Homo sapiens] 72 3e-12
gi|50345997 E1A binding protein p300 [Homo sapiens] 71 4e-12
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 71 4e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 71 5e-12
gi|56549696 E1A binding protein p400 [Homo sapiens] 71 5e-12
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 70 7e-12
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 70 9e-12
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 68 3e-11
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 68 3e-11
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 68 4e-11
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 68 4e-11
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 68 4e-11
>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
Length = 898
Score = 1819 bits (4711), Expect = 0.0
Identities = 898/898 (100%), Positives = 898/898 (100%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
Query: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ
Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
Query: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
Query: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
Query: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
Query: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
Query: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
Query: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
Query: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
Query: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
Length = 898
Score = 1819 bits (4711), Expect = 0.0
Identities = 898/898 (100%), Positives = 898/898 (100%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
Query: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ
Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
Query: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
Query: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
Query: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
Query: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
Query: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
Query: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
Query: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
Query: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
>gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3
[Homo sapiens]
Length = 837
Score = 1629 bits (4219), Expect = 0.0
Identities = 826/898 (91%), Positives = 827/898 (92%), Gaps = 61/898 (6%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
PQKQARTSSSTTPNRK TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295
Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355
Query: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
VQPQLQQEAEPQKQVQPQV QA QP VQPQ H PP QV
Sbjct: 356 VQPQLQQEAEPQKQVQPQVHTQA--------------------QPSVQPQEH--PPAQVS 393
Query: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
+Q PP Q QP HTQPQVSLLAPEQTP
Sbjct: 394 VQ--------------------------PPEQTHEQP--------HTQPQVSLLAPEQTP 419
Query: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 420 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 479
Query: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 480 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 539
Query: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 540 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 599
Query: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 600 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 659
Query: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 660 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 719
Query: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 720 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 779
Query: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 780 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 837
>gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2
[Homo sapiens]
Length = 842
Score = 1616 bits (4184), Expect = 0.0
Identities = 819/898 (91%), Positives = 830/898 (92%), Gaps = 56/898 (6%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
EALEAQVLPRFQPRVLQVQAQVQS Q QP++ T T Q
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQS-----------QTQPRIPS---TDT----------Q 336
Query: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
VQP+LQ++A+ Q P + LQQ KQVQPQ+Q +A +P +QVQ
Sbjct: 337 VQPKLQKQAQTQTS-------------PEHLVLQQ-----KQVQPQLQQEA--EPQKQVQ 376
Query: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 377 ------------PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 424
Query: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 425 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 484
Query: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 485 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 544
Query: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 545 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 604
Query: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 605 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 664
Query: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 665 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 724
Query: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 725 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 784
Query: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 785 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 842
>gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4
[Homo sapiens]
Length = 818
Score = 1554 bits (4023), Expect = 0.0
Identities = 795/898 (88%), Positives = 806/898 (89%), Gaps = 80/898 (8%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG
Sbjct: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 97 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276
Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
EALEAQVLPRFQPRVLQVQAQVQS Q QP++ T T Q
Sbjct: 277 EALEAQVLPRFQPRVLQVQAQVQS-----------QTQPRIPS---TDT----------Q 312
Query: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
VQP+LQ++A+ Q P + LQQ KQVQPQ+Q +A +P +QVQ
Sbjct: 313 VQPKLQKQAQTQTS-------------PEHLVLQQ-----KQVQPQLQQEA--EPQKQVQ 352
Query: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 353 ------------PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 400
Query: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 401 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 460
Query: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 461 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 520
Query: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 521 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 580
Query: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 581 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 640
Query: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 641 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 700
Query: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 701 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 760
Query: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 761 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 818
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 89.4 bits (220), Expect = 1e-17
Identities = 161/602 (26%), Positives = 217/602 (36%), Gaps = 87/602 (14%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQL-QQQQLQQQQL--LQLQQLLQQSPPQAPLPMAVSRGLP 60
Q QQQQ QQQQQLQQ QQQQL QQQQLQQQQL Q QQ LQQ Q
Sbjct: 3899 QLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQ 3958
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
QQ QQ Q LLN S R LL Q Q Q A+ P MP L
Sbjct: 3959 QQQQQQQFQQQQQQQQMGLLNQS---RTLLSPQQQQQQQVALGPG--------MPAKPLQ 4007
Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP-VGVPMNPSQFNLSGR 179
+ +SPG P+L L P + ++ GP G P+ G
Sbjct: 4008 H-----FSSPGALGPTLL---LTGKEQNTVDPAVSSEATEGPSTHQGGPL------AIGT 4053
Query: 180 NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239
P+ A P+ SQ + V+ + P S + P + Q
Sbjct: 4054 TPESMATEPGEVKPS-LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAG 4112
Query: 240 KEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK----AQPQARMTVPKQT-- 293
EAS +P L + + + PG + QP + T
Sbjct: 4113 GGSHGQLGSGSSSEASSVP--HLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGP 4170
Query: 294 QTPDLLPEALEAQVLP--RFQPRVLQVQAQVQS------QTQPRIPSTDTQVQPKL-QKQ 344
Q P P Q LP P V Q++AQ+Q Q + P Q+Q L Q+Q
Sbjct: 4171 QPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQ 4230
Query: 345 AQ---------------TQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPR 389
Q TQTSP +L QPQL PQ ++ QGP
Sbjct: 4231 LQQSQAVRQTPPYQEPGTQTSPLQGLL---GCQPQLGGFPGPQTGPLQELGAGPRPQGPP 4287
Query: 390 QVQLQQEA----EPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQ-PSVQ 444
++ A L V P P + +P R QL Q+ T+AQ P
Sbjct: 4288 RLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS-------QLPTEAQLPPTH 4340
Query: 445 PQEHPPAQVSVQPPEQTHEQPHTQPQVSL----LAPEQTPVVVHVCGLEMPPDAVEAGGG 500
P P +++PP Q +L L P P ++ + P + G
Sbjct: 4341 PGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP--DNLAETQKPEQSSLVPGH 4398
Query: 501 MEKTLPE--PVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDS 558
+++ + P +Q+S+++ E C L + A P GA G+ +L S
Sbjct: 4399 LDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEP--IGAPGTSNHLLLAGPRS 4456
Query: 559 RA 560
A
Sbjct: 4457 EA 4458
Score = 85.1 bits (209), Expect = 3e-16
Identities = 138/536 (25%), Positives = 198/536 (36%), Gaps = 76/536 (14%)
Query: 4 QQQQQQLQQQQQQ----LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAP-----LPMA 54
Q+Q Q+++QQ++ + + + +Q QQQQ QQQQ Q +L SP Q+P LP
Sbjct: 3575 QKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQ 3634
Query: 55 VSRGLPPQQPQQP--------LLNLQGTNSASLLNGSMLQRALLLQQLQ----GLDQFAM 102
+ G Q PQ P L G G L AL QQ Q G A
Sbjct: 3635 LLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAG 3694
Query: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQ----LATPNLQQFFPQATRQS 158
P + L LR G S L L Q LA QQ Q +Q
Sbjct: 3695 PSGGFFPGNLA--------LRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQH 3746
Query: 159 LLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKS-DPPEGSEE 217
LLG + Q G Q SS Q + V+ S PP+G +
Sbjct: 3747 LLGQVAI------QQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQG 3800
Query: 218 AAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL 277
L P + +++ A P+ P +++ ++ P
Sbjct: 3801 M------------LGPAQVAVLQQQHPGALGPQG------PHRQVLMTQSRVLSSPQLAQ 3842
Query: 278 QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 337
Q + R+ +Q Q + L Q ++ Q + QP Q
Sbjct: 3843 QGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQ 3902
Query: 338 QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEA 397
Q +LQ+Q Q Q + QQ Q Q QLQQ+ Q+Q Q Q+Q Q +Q QLQQ+
Sbjct: 3903 QQQLQQQQQLQQQQQ----QQLQQQQQLQQQQLQQQQQQQQLQQQ------QQQQLQQQQ 3952
Query: 398 EPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQP 457
+ L+Q Q Q Q Q Q +Q Q+ L Q +T PQ Q Q ++ P + +P
Sbjct: 3953 QQLQQ-QQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGP------GMPAKP 4005
Query: 458 PEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGME-KTLPEPVGTQ 512
+ P + L EQ V V + GG + T PE + T+
Sbjct: 4006 LQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATE 4061
Score = 68.2 bits (165), Expect = 3e-11
Identities = 99/389 (25%), Positives = 147/389 (37%), Gaps = 47/389 (12%)
Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 189
P L+PP +P P+A+R L PPP PM+P P + +R S
Sbjct: 601 PPFEESPLSPPPEESPLSPP--PEASR---LSPPPEDSPMSPPPEESPMSPPPEVSRLSP 655
Query: 190 STTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEP 249
+R + P+ S PPE S P PE L P PED +P P
Sbjct: 656 LPVVSRLSPPPEESPL---SPPPEES-----PTSPPPEASRLSPPPED-----SPTSPPP 702
Query: 250 EPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 309
E AS P L S P E+ P L + +PQ + +++ P L P E + P
Sbjct: 703 EDSPASPPPEDSLMSL--PLEESP--LLPLPEEPQ----LCPRSEGPHLSPRPEEPHLSP 754
Query: 310 RFQPRVLQVQA-QVQSQTQPRIPS-TDTQVQPKLQKQAQ---TQTSPEHLVLQQKQVQPQ 364
R + L QA + QP P +P L QA+ PE L L + +P
Sbjct: 755 RPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH 814
Query: 365 LQQEAE-----PQKQ---VQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPP 416
L E PQ + + PQ + S P + L E E +P + P+ P
Sbjct: 815 LSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELE-----KPPLSPRPEKPPE 869
Query: 417 RQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQP-PEQTHEQPHTQPQVS--L 473
Q +++ P + + +P P + + P PE+ P +P +S L
Sbjct: 870 EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929
Query: 474 LAPEQTPVVVHVCGLEMPPDAVEAGGGME 502
+ P+ P + P A+ G +E
Sbjct: 930 MPPDPLPPPLSPIITAAAPPALSPLGELE 958
Score = 63.2 bits (152), Expect = 1e-09
Identities = 131/532 (24%), Positives = 194/532 (36%), Gaps = 148/532 (27%)
Query: 4 QQQQQQLQQQQQQL-QQLQQQQLQQQQLQQQQLL---QLQQLLQQSP-----------PQ 48
Q++Q QLQQQ+ QL Q+LQQQ QQQQ QQQ LL +QQ QQ P PQ
Sbjct: 3717 QERQLQLQQQRMQLAQKLQQQ--QQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQ 3774
Query: 49 APLPMAVSRG-----LPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMP 103
+P + +G L PQ PQ P QG + Q A+L QQ G
Sbjct: 3775 GLMPPSSHQGLLVQQLSPQPPQGP----QGMLGPA-------QVAVLQQQHPG------- 3816
Query: 104 PATYDTAGLTMPTATLGNLRGYGMASPGLA--APSLTPPQLATPNLQQFFPQATRQSLLG 161
G P + + ++SP LA L +L T QQ Q +Q
Sbjct: 3817 -----ALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQG--- 3868
Query: 162 PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP 221
+++G + +Q+ S S P S P GS + +
Sbjct: 3869 -------------SMAGLSHLQQSLMSHSGQPK-------------LSAQPMGSLQQLQQ 3902
Query: 222 RMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 281
+ + Q L + ++++ +L ++L+ ++ + + Q Q++
Sbjct: 3903 QQQLQQQQQLQQQQQQQLQQQQ------------QLQQQQLQQQQQQQQLQQQQQQQLQQ 3950
Query: 282 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 341
Q Q Q+ + Q + Q Q Q Q Q + + T + P+
Sbjct: 3951 QQQ---------------------QLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQ 3989
Query: 342 QKQAQTQTSPEHLVLQQKQVQ---------PQLQQEAEPQKQVQPQVQ------PQAHSQ 386
Q+Q Q P + K +Q P L + Q V P V P H
Sbjct: 3990 QQQQQVALGPG---MPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQG 4046
Query: 387 GPRQVQLQQEA---EP------------LKQVQPQVQPQAHS---QPPRQVQLQLQKQVQ 428
GP + E+ EP L VQPQ QPQ S QPP ++ Q Q+QV
Sbjct: 4047 GPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVS 4106
Query: 429 T--QTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQ 478
H Q + + QP +QP + Q +LL P+Q
Sbjct: 4107 LLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQ-NLLGPQQ 4157
Score = 56.6 bits (135), Expect = 1e-07
Identities = 99/419 (23%), Positives = 153/419 (36%), Gaps = 52/419 (12%)
Query: 137 LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS---SSTTP 193
L+PP +P P+A+R L PPP +P +P L P +++ S +
Sbjct: 449 LSPPPEESPTSPP--PEASR---LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503
Query: 194 NRKDSSSQTMPVEDKS-DPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 252
+ SS P+E+ PPE E P ++TP P E+ +P PE
Sbjct: 504 SPPPESSPFSPLEESPLSPPE--ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561
Query: 253 EASELP-AKRLR-SSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP- 309
S P A RL EE PP + + P+A P ++P L P E+ + P
Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP-LSPPPEESPLSPP 620
Query: 310 ----RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ--- 362
R P + P P + L ++ PE L +
Sbjct: 621 PEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680
Query: 363 ---PQLQQEAEPQKQVQPQVQPQAHSQGP----RQVQLQQEAEPLKQV--QPQVQPQAHS 413
P+ + + P + P+ P + L E PL + +PQ+ P++
Sbjct: 681 SPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG 740
Query: 414 Q--PPRQVQLQLQKQVQTQTYPQVHTQA-QPSVQPQEHPPAQVSVQPPEQTH-----EQP 465
PR + L + + P + QA +P + PQ P +V PE+ H E P
Sbjct: 741 PHLSPRPEEPHLSPRPEE---PHLSPQAEEPHLSPQPEEPCLCAV--PEEPHLSPQAEGP 795
Query: 466 HTQPQVSLL-------APEQTPVVVHVCGLEMPPDAVEAGGGMEKTL-PEPVGTQVSME 516
H PQ L P +PV C P ++ + E L P P + +S E
Sbjct: 796 HLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854
Score = 50.4 bits (119), Expect = 7e-06
Identities = 98/443 (22%), Positives = 166/443 (37%), Gaps = 80/443 (18%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
+ ++++LQ++QQ QLQ Q QQQQ QQ LL P QA
Sbjct: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLS-----APGPAQA-------------- 3294
Query: 64 PQQPLLNLQGTNSASLLNGSMLQRALLL--QQLQGLDQFAMP--PATYDTAGLTMPTATL 119
++L S+ L GS Q +L L + GL Q MP P + P+ +
Sbjct: 3295 -----MSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAM 3349
Query: 120 GNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR 179
+ +G+ ++ L P Q + P L Q +G P + M P Q +
Sbjct: 3350 VSNQGHMLSGQHGGQAGLVPQQSSQPVLS--------QKPMGTMPPSMCMKPQQLAM--- 3398
Query: 180 NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCP--- 235
Q + ++S P D+ ED DP ++ A + Q + P
Sbjct: 3399 ----QQQLANSFFP---DTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMN 3451
Query: 236 ---EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP------PGQLQVKAQPQAR 286
+ ++ + P + + + RS+ +P++ P G + Q Q
Sbjct: 3452 RQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYE 3511
Query: 287 MTVPKQTQTPDLLPEALEAQV-LPRFQPRVLQVQAQVQSQTQPRIPSTD-------TQVQ 338
+ Q + + LE Q+ + R + L + + + P D T+ Q
Sbjct: 3512 EWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQ 3571
Query: 339 PKLQKQ----AQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQ 394
K+QKQ + Q +L+ + + Q Q QQ+ + Q+Q V + SQ PR
Sbjct: 3572 SKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRL---- 3627
Query: 395 QEAEPLKQVQPQVQPQAHSQPPR 417
L ++ Q+ P QPP+
Sbjct: 3628 -----LTKLPGQLLPGHGLQPPQ 3645
Score = 45.1 bits (105), Expect = 3e-04
Identities = 96/470 (20%), Positives = 157/470 (33%), Gaps = 96/470 (20%)
Query: 132 LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS--- 188
++ P P P + + P S L PPP P++P P + +R S
Sbjct: 635 MSPPPEESPMSPPPEVSRLSPLPV-VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP 693
Query: 189 --SSTTPNRKDS--------SSQTMPVEDKSDPPEGSEEAAEPRMD------TPEDQDLP 232
S T+P +DS S ++P+E+ P E PR + PE+ L
Sbjct: 694 EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLS 753
Query: 233 PCPED--IAKEKRTPAPEPEP-----CEASELP-----AKRLRSSEEPTE-------KEP 273
P PE+ ++ + P P+P C E P A+ S +P E +EP
Sbjct: 754 PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813
Query: 274 -----PGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQP 328
P + + QP+ P Q++ P L P E+ + P + L + + +
Sbjct: 814 HLSPVPEEPCLSPQPEESHLSP-QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG 872
Query: 329 RIPSTDT----------QVQPKLQKQAQTQTS-------PEHLVLQQKQVQPQLQQEAEP 371
+ P+ + + P L + A ++ PE L L +P L + P
Sbjct: 873 QCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG-EPSLSPQLMP 931
Query: 372 QKQVQPQVQPQAHSQGPRQVQLQQEAE-----------------PLKQVQPQVQPQAHSQ 414
+ P + P + P + E E P+ + P+A+
Sbjct: 932 PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCT 991
Query: 415 PPRQVQLQLQKQ------------VQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTH 462
P V + + PQ Q S+ PQ PP+Q S PP
Sbjct: 992 DPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCS--PPALPL 1049
Query: 463 EQPHTQPQVSLLAPEQTPVVVHVCGLE--MPPDAVEAGGGMEKTLPEPVG 510
P + + +H E P+ LP P+G
Sbjct: 1050 SVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMG 1099
Score = 42.4 bits (98), Expect = 0.002
Identities = 84/395 (21%), Positives = 127/395 (32%), Gaps = 65/395 (16%)
Query: 103 PPATYDTAGLTMPTATLG---NLRGY---------GMASPG---LAAPSLTPPQLATPN- 146
PPA T + PT G + G+ G SPG L P P Q+ + +
Sbjct: 2117 PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDP 2176
Query: 147 --------LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDS 198
L+ FP A P P G P P S R Q +T P
Sbjct: 2177 FGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPG---- 2232
Query: 199 SSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASE-- 256
P S P + +PR + ++ +P P + P P P S
Sbjct: 2233 ----TPRHQPSTP----DPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKA 2284
Query: 257 LPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 316
L K+ PP V + + +TPD+ +A + PR
Sbjct: 2285 LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDV----FKAPLTPR------ 2334
Query: 317 QVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQ 376
SQ +P+ P + Q QA + P H + +P + Q +
Sbjct: 2335 ------ASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI----FRPGSYTDPYAQPPLT 2384
Query: 377 PQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTY-PQV 435
P+ QP ++P +V Q Q+ SQ P + + + + P
Sbjct: 2385 PRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSP-----LTPRPLSAEAFCPSP 2439
Query: 436 HTQAQPSVQPQEHPPAQVSVQPP-EQTHEQPHTQP 469
T S P PP++ + P H+ P QP
Sbjct: 2440 VTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQP 2474
Score = 40.4 bits (93), Expect = 0.007
Identities = 82/385 (21%), Positives = 135/385 (35%), Gaps = 57/385 (14%)
Query: 129 SPGLAAPSLTPPQLATPNLQQFFP--QATRQSL------LGPPPVGVPMNPSQ-FNLSGR 179
SPG+ + P L+ P + + ++ L GPP +G +PS +L G
Sbjct: 2260 SPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGL 2319
Query: 180 NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239
+ + TP Q+ + + P ++ A P+ + A
Sbjct: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYA 2379
Query: 240 KEKRTPAPEPEPCEAS-ELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDL 298
+ TP P+P P E+ LP + L S +P + P A PQ++ + +Q+P
Sbjct: 2380 QPPLTPRPQPPPPESCCALPPRSLPS--DPFSRVP-------ASPQSQSS----SQSP-- 2424
Query: 299 LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
PR L +A S PR S D +P + Q++ +P H +
Sbjct: 2425 ------------LTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP 2472
Query: 359 KQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ 418
+ + + + + P A GP A L P QP + P
Sbjct: 2473 QPPEVAFKAGSLAHTSLGAGGFPAALPAGP--------AGELHAKVPSGQPPNFVRSPGT 2524
Query: 419 VQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQ 478
T+PQ +PS++P P Q + PP + H P +L P+
Sbjct: 2525 GAFVGTPSPMRFTFPQ--AVGEPSLKP---PVPQPGLPPPHGINS--HFGPGPTLGKPQS 2577
Query: 479 TPVVV-----HVCGLEMPPDAVEAG 498
T V H G + P + G
Sbjct: 2578 TNYTVATGNFHPSGSPLGPSSGSTG 2602
Score = 37.4 bits (85), Expect = 0.063
Identities = 44/185 (23%), Positives = 71/185 (38%), Gaps = 8/185 (4%)
Query: 315 VLQVQAQVQSQTQPRIPS-TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQK 373
V + V S+ P P T T L Q Q H+ Q + LQ EA+P
Sbjct: 361 VAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG 420
Query: 374 QVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ-LQKQVQTQTY 432
+ Q++PQ + ++ L E + P + S PP +L +++
Sbjct: 421 KAGVQLEPQLEAPLNEEMPLLPPPEE-SPLSPPPEESPTSPPPEASRLSPPPEELPASPL 479
Query: 433 PQ-VHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP--EQTPVVVHVCGLE 489
P+ +H P PP + + PP ++ P + + S L+P E P L
Sbjct: 480 PEALHLSRPLEESPLSPPPEESPLSPPPES--SPFSPLEESPLSPPEESPPSPALETPLS 537
Query: 490 MPPDA 494
PP+A
Sbjct: 538 PPPEA 542
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 89.4 bits (220), Expect = 1e-17
Identities = 105/375 (28%), Positives = 155/375 (41%), Gaps = 57/375 (15%)
Query: 153 QATRQSLLGPPPVGVPMNPSQFNLSGRNP----QKQARTSSSTTPNRKDSSSQTMPVEDK 208
Q T Q L P V V P Q + P Q+ T +TT +++ T+
Sbjct: 2174 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTT-A 2232
Query: 209 SDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEP 268
+ E + P+M +D+ LPP P EA A+ +
Sbjct: 2233 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG----------PAEAQPQTAQPSAQPQPQ 2282
Query: 269 TEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP----EALEAQVLPRFQPRVLQVQAQ--- 321
T+ + P Q +V+ QP+ + + P ++ + QV + QP+ VQ Q
Sbjct: 2283 TQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQS-NVQGQSPV 2341
Query: 322 -VQSQTQPRI-PSTDTQVQPKLQKQAQTQTSPE-----HLVLQ-----QKQVQPQLQQEA 369
VQS +Q RI PST +Q+ P Q Q QT TS H LQ Q Q QPQ+Q
Sbjct: 2342 RVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSST 2401
Query: 370 EP--------QKQVQPQVQPQAHSQGPR-QV----QLQQEAEPLKQVQPQVQPQAHSQP- 415
+ Q V +PQ Q P+ QV QLQQ+ + L Q+Q QV Q +Q
Sbjct: 2402 QTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQS 2461
Query: 416 --PRQVQLQL------QKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHT 467
P+Q++LQL VQT V T SVQ Q Q+ Q ++ +Q
Sbjct: 2462 GVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEI 2521
Query: 468 QPQVSLLAPEQTPVV 482
+ + +L A Q+ ++
Sbjct: 2522 KREHTLQASNQSEII 2536
Score = 77.4 bits (189), Expect = 6e-14
Identities = 78/272 (28%), Positives = 115/272 (42%), Gaps = 54/272 (19%)
Query: 282 QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
Q Q++++ Q LP A + V P QP+ Q AQ Q QTQP+ P+ QP+
Sbjct: 2238 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2292
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
+Q Q + QT + QP Q ++PQ V Q QPQ++ QG V++Q +
Sbjct: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQ--VAAQSQPQSNVQGQSPVRVQSPS--- 2347
Query: 401 KQVQPQVQPQAHSQ--PPRQVQLQLQKQ----VQTQTYPQVHTQAQPSVQPQ-------- 446
Q +++P SQ P +Q Q+Q +Q T Q+ +Q QP QPQ
Sbjct: 2348 ---QTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTL 2404
Query: 447 --------------EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 492
P Q+ QP Q P Q QV +L+ Q+ VV +
Sbjct: 2405 SSGQTLNQVTVSSPSRPQLQIQ-QPQPQVIAVPQLQQQVQVLSQIQSQVVAQI------- 2456
Query: 493 DAVEAGGGMEKTLPEPVGTQ----VSMEEIQN 520
A ++G + L P+ Q V +IQN
Sbjct: 2457 QAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQN 2488
Score = 61.6 bits (148), Expect = 3e-09
Identities = 62/221 (28%), Positives = 84/221 (38%), Gaps = 15/221 (6%)
Query: 275 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334
GQLQ+ Q + P Q L+ A+ + RF L A S T + +T
Sbjct: 2177 GQLQLIPQGVTVLPGPGQ----QLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTA 2232
Query: 335 T----QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQ 390
Q Q KL Q Q Q V P Q Q QPQ Q Q S +
Sbjct: 2233 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2292
Query: 391 VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPP 450
VQ Q E + V V +A P Q + QV Q+ PQ + Q Q V+ Q P
Sbjct: 2293 VQTQPEVQTQTTVSSHVPSEAQ---PTHAQ-SSKPQVAAQSQPQSNVQGQSPVRVQS--P 2346
Query: 451 AQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 491
+Q ++P + P Q QV + P+ H L++P
Sbjct: 2347 SQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2386
Score = 33.5 bits (75), Expect = 0.91
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 16/102 (15%)
Query: 3 SQQQQQQLQQQQQQLQQLQQQQLQQQ-----QLQQQQLLQLQQLLQQSPPQAPLPMAVSR 57
S + QLQ QQ Q Q + QLQQQ Q+Q Q + Q+Q Q+ +P +
Sbjct: 2416 SSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQ------AQQSGVPQQIKL 2469
Query: 58 GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQ 99
LP Q Q + + N +Q A + +QLQ + Q
Sbjct: 2470 QLPIQIQQS-----SAVQTHQIQNVVTVQAASVQEQLQRVQQ 2506
Score = 32.7 bits (73), Expect = 1.6
Identities = 95/475 (20%), Positives = 150/475 (31%), Gaps = 73/475 (15%)
Query: 164 PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
P+GVP P + PQ++ SS+ P R ++ QT PV ++ E E E R
Sbjct: 1844 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 1899
Query: 224 DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 282
+++ E AK++ ++ P S+ P +K +
Sbjct: 1900 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 1959
Query: 283 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 332
+M + + +P + F V Q Q+ QVQ + IPS
Sbjct: 1960 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2019
Query: 333 --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 374
T T QP+ T+ V+ Q++P + P +Q
Sbjct: 2020 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2079
Query: 375 ----VQPQVQPQAHSQ------------GPRQVQLQQEAEPLKQVQPQVQPQAH-SQPPR 417
VQP Q +Q P V + L Q+ SQPPR
Sbjct: 2080 TPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPR 2139
Query: 418 QVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQ---VSVQPPEQTHEQPHTQPQVSLL 474
Q Q++ T AQ + Q H Q V +Q QT Q PQ +
Sbjct: 2140 PQQGQVKL-----------TMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTV 2188
Query: 475 APEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENR 534
P ++ A G +++ L P+ T + + G E R
Sbjct: 2189 LPGPGQQLM---------QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQR 2239
Query: 535 AREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQ 589
++ + QSS P T P + P + + P Q
Sbjct: 2240 QSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQ 2294
Score = 31.6 bits (70), Expect = 3.5
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%)
Query: 709 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 761
+ D E + E+++ ++E+ +GD EE +D ED+EE E+EE+
Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 89.0 bits (219), Expect = 2e-17
Identities = 91/324 (28%), Positives = 133/324 (41%), Gaps = 51/324 (15%)
Query: 5 QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54
Q QQQ+QQQQQQLQ++ QQQQ QQQQ QQQQ LQ Q +QQ P PQ P A
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285
Query: 55 VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAM 102
+ + L PP QPQQP + N S L + L+ Q L G +
Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Query: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL--- 159
PP + A + + + + A + Q+ P +Q + +
Sbjct: 343 PPLKFVRAPMVVQQPPVQP----QVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIR 398
Query: 160 -LGPPPVGVPMNPSQFNLSGRNPQKQARTS-----SSTTPNRKDSSSQTMPVEDKSDPPE 213
PP V PS GR P Q S SS +P ++ + Q+MP PP+
Sbjct: 399 ARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMP-----PPPQ 453
Query: 214 GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 273
S + +P + P P + P+P P+P + S + A+ ++ P+
Sbjct: 454 PSPQPGQPSSQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS---- 505
Query: 274 PGQLQVKAQPQARMTVPKQTQTPD 297
PG L P + M+ +Q +
Sbjct: 506 PGPLNTPVNPSSVMSPAGSSQAEE 529
Score = 76.3 bits (186), Expect = 1e-13
Identities = 65/197 (32%), Positives = 90/197 (45%), Gaps = 17/197 (8%)
Query: 276 QLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDT 335
Q Q++ Q A +Q Q AL+ Q + Q + Q+ +Q Q Q +
Sbjct: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVV----- 204
Query: 336 QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQ 395
Q Q +LQ+Q Q Q +HL+ Q Q Q+QQ+ Q+Q+Q Q Q Q +Q Q QQ
Sbjct: 205 QQQQQLQQQQQQQ---QHLIKLHHQNQQQIQQQ---QQQLQRIAQLQLQQQQQQQQQQQQ 258
Query: 396 EAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSV 455
+ + Q QP +Q QP L +Q+Q + Q H QP QPQ+ P AQ
Sbjct: 259 QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH---QPPPQPQQPPVAQ--- 312
Query: 456 QPPEQTHEQPHTQPQVS 472
P Q Q TQP VS
Sbjct: 313 NQPSQLPPQSQTQPLVS 329
Score = 72.0 bits (175), Expect = 2e-12
Identities = 83/282 (29%), Positives = 120/282 (42%), Gaps = 23/282 (8%)
Query: 246 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 305
AP ++ P +L+ + +++ Q Q + Q QA + +Q Q +A ++
Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194
Query: 306 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 364
+ +FQ V Q Q Q Q Q Q + Q Q ++Q+Q Q L LQQ+Q Q Q
Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254
Query: 365 LQQEAEPQK-QVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQL 423
QQ+ + Q Q QP +Q Q P Q ++ L Q Q+ H QPP Q Q
Sbjct: 255 QQQQQQQQALQAQPPIQ-----QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPP 309
Query: 424 QKQVQTQTYPQVHTQAQPSV-QPQEHPPAQVSVQPP----------EQTHEQPHTQPQVS 472
Q Q P +Q QP V Q Q P + QPP +Q QP Q Q +
Sbjct: 310 VAQNQPSQLPP-QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQT 368
Query: 473 LLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVS 514
+ Q +V G++M +A+ A GGM P T VS
Sbjct: 369 AVQTAQAAQMV-APGVQMITEAL-AQGGMHIRARFPPTTAVS 408
Score = 66.2 bits (160), Expect = 1e-10
Identities = 100/437 (22%), Positives = 148/437 (33%), Gaps = 85/437 (19%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
QQQQQQ QQQQQ Q QQQQ QQQQ Q QQ QQ Q L QQ
Sbjct: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ-------QQQ 215
Query: 64 PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLR 123
QQ L+ L N + + + QLQ Q L
Sbjct: 216 QQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL----------- 264
Query: 124 GYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQK 183
A P + P + PQ P Q PQ +Q M+ +Q + PQ
Sbjct: 265 ---QAQPPIQQPPMQQPQ---PPPSQALPQQLQQ-----------MHHTQHHQP--PPQP 305
Query: 184 QARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMD---TPEDQDLPPCPEDIAK 240
Q + P++ SQT P+ ++ G +P + P PP + +
Sbjct: 306 QQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
Query: 241 EKRTPAPEPEPCEASELPA---------------------------KRLRSSEEPTEKEP 273
++ + +A+++ A + SS P ++P
Sbjct: 366 QQTA----VQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQP 421
Query: 274 PGQLQVKAQPQARMTVP-KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS 332
Q+ + P P +Q QTP +P + P QP Q + V S P S
Sbjct: 422 MAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG-QPS-SQPNSNVSSGPAPSPSS 479
Query: 333 TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQ 392
P+ + T +P++ + L P + P G Q +
Sbjct: 480 FLPSPSPQPSQSPVTARTPQNFSVPS---PGPLNTPVNPSSVMSP--------AGSSQAE 528
Query: 393 LQQEAEPLKQVQPQVQP 409
QQ + LKQ+ ++P
Sbjct: 529 EQQYLDKLKQLSKYIEP 545
Score = 33.9 bits (76), Expect = 0.70
Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Query: 378 QVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQV----QTQTYP 433
Q P P + + A P Q Q Q+Q A Q +Q Q Q Q+Q Q Q
Sbjct: 128 QPPPGTSGMAPHSMAVVSTATP--QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ 185
Query: 434 QVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 468
Q QAQ S Q+ Q VQ +Q +Q Q
Sbjct: 186 QQQFQAQQSAMQQQF---QAVVQQQQQLQQQQQQQ 217
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 84.7 bits (208), Expect = 3e-16
Identities = 91/331 (27%), Positives = 143/331 (43%), Gaps = 30/331 (9%)
Query: 193 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 252
P+ S +++ +P E + P + P +IA+E R
Sbjct: 39 PDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGAS------EIAEETRPGQ------ 86
Query: 253 EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ 312
EL ++L EP ++ QLQ QPQ + + +Q P+ Q L + Q
Sbjct: 87 --RELQLQQLEQQPEPQQQPQHEQLQ---QPQPHLELQQQ-------PQQDGQQQLSQLQ 134
Query: 313 PRVLQVQAQVQSQTQPRIPSTDTQVQPK-LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEP 371
Q + + + ++ Q+QP+ +Q+Q + Q E L QQ Q Q LQQ+ +
Sbjct: 135 QEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQL 194
Query: 372 QKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQT 431
Q+QVQ Q Q + +Q QL Q+ E L+Q Q Q Q + Q + + LQ Q Q+Q Q
Sbjct: 195 QQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL 254
Query: 432 YPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 491
Q QAQ Q E AQ+ Q Q EQ Q Q LL +Q + L+ P
Sbjct: 255 LQQ--QQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQ--QLQPP 310
Query: 492 PDAVEAGGGME-KTLPEPVGTQVSMEEIQNE 521
P E +E + +P +G++ +E+ + E
Sbjct: 311 PLEPEEEEEVELELMPVDLGSEQELEQQRQE 341
Score = 75.1 bits (183), Expect = 3e-13
Identities = 86/323 (26%), Positives = 139/323 (43%), Gaps = 37/323 (11%)
Query: 171 PSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ- 229
P LSG + +++ P ++SS Q V S P SE A E R E Q
Sbjct: 37 PGPDTLSGGSGGSESQEEEE--PQERNSSPQRPAV---SAPVGASEIAEETRPGQRELQL 91
Query: 230 ---DLPPCPEDIAKEKRTPAPEP------EPCEASELPAKRLRSSEEPTEKEPPGQLQVK 280
+ P P+ + ++ P+P +P + + +L+ + + + +++
Sbjct: 92 QQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQ 151
Query: 281 AQPQARMTVPKQTQTPDLLPEALEA-QVLPRFQPRVLQVQAQVQSQTQPR--IPSTDTQV 337
Q + P+Q Q L + E Q + +VLQ Q Q+Q Q Q + + Q+
Sbjct: 152 LMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQL 211
Query: 338 QPKLQKQAQTQTSPEHLVLQQKQVQPQ-----LQQEAEPQKQVQPQVQPQAHSQ--GPRQ 390
Q + Q Q Q + QQ+Q+Q Q LQQ+ + Q+Q+ Q Q Q Q +Q
Sbjct: 212 QQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQ 271
Query: 391 VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPP 450
QLQQ+ L Q Q Q+Q Q Q +Q Q QLQ+Q Q P P ++P+E
Sbjct: 272 AQLQQQL--LLQQQEQLQQQQQQQLLQQQQEQLQQQ---QLQP-------PPLEPEEEEE 319
Query: 451 AQVSVQPPEQTHEQPHTQPQVSL 473
++ + P + EQ Q + L
Sbjct: 320 VELELMPVDLGSEQELEQQRQEL 342
Score = 61.2 bits (147), Expect = 4e-09
Identities = 61/235 (25%), Positives = 106/235 (45%), Gaps = 21/235 (8%)
Query: 253 EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ 312
+ +L ++L +E +++ Q Q + Q Q ++ + +Q L + L+ Q Q
Sbjct: 207 QQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQG--QLQQQLLQQQQAQLQQ 264
Query: 313 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ 372
+ Q QAQ+Q Q Q Q +LQ+Q Q Q +LQQ+Q Q Q QQ P
Sbjct: 265 QLLEQQQAQLQQQLL-------LQQQEQLQQQQQQQ------LLQQQQEQLQQQQLQPPP 311
Query: 373 KQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTY 432
+ + + + + P + +QE E +Q + Q Q RQ+QL+LQ+++Q
Sbjct: 312 LEPEEEEEVELELM-PVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQ---- 366
Query: 433 PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCG 487
Q+ Q + Q E Q+ + P E +Q Q +++ + PE +V G
Sbjct: 367 -QLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAG 420
Score = 59.3 bits (142), Expect = 2e-08
Identities = 50/107 (46%), Positives = 59/107 (55%), Gaps = 19/107 (17%)
Query: 5 QQQQQLQQQ-------QQQLQQLQQQQL--QQQQLQQQQLLQLQQLLQQSPPQAPLPMAV 55
QQQ+QLQQQ QQQ +QLQQQQL QQ+QLQQQQ Q Q+ LQQ Q L +
Sbjct: 189 QQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQ---QQQLLLLQ 245
Query: 56 SRGLPPQQPQQPLLNLQGTNSASLL---NGSMLQRALLLQQLQGLDQ 99
+G Q QQ LL Q L + LQ+ LLLQQ + L Q
Sbjct: 246 QQG----QLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288
Score = 57.4 bits (137), Expect = 6e-08
Identities = 40/96 (41%), Positives = 47/96 (48%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
M QQQ Q Q Q+QQ Q QQ+QLQ QQ Q+QQ+LQ Q+ LQQ + L L
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212
Query: 61 PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG 96
QQ Q LQ Q+ LLL Q QG
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQG 248
Score = 57.0 bits (136), Expect = 8e-08
Identities = 35/66 (53%), Positives = 40/66 (60%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
QQQQ+QLQQQQQ L QQ QLQQQ LQQQQ QQLL+Q Q + + + QQ
Sbjct: 229 QQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288
Query: 64 PQQPLL 69
QQ L
Sbjct: 289 QQQQQL 294
Score = 54.7 bits (130), Expect = 4e-07
Identities = 47/102 (46%), Positives = 57/102 (55%), Gaps = 9/102 (8%)
Query: 5 QQQQQLQQQQQQLQ--QLQQQQL--QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSR--G 58
Q+QQ+LQQQQ+QLQ Q Q+QQ+ QQ+QLQQQ +Q QQLLQQ Q + +
Sbjct: 165 QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQ--VQEQQLLQQQQEQLQQQQLLQQQEQ 222
Query: 59 LPPQQPQQPLLNLQGTNSASLL-NGSMLQRALLLQQLQGLDQ 99
L QQ QQ LQ LL LQ+ LL QQ L Q
Sbjct: 223 LQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQ 264
Score = 51.6 bits (122), Expect = 3e-06
Identities = 39/69 (56%), Positives = 42/69 (60%), Gaps = 5/69 (7%)
Query: 5 QQQQQLQQQ--QQQLQQLQQQQLQQQ--QLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
QQQ QLQQQ QQQ QLQQQ L+QQ QLQQQ LLQ Q+ LQQ Q L + L
Sbjct: 245 QQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQ-LQ 303
Query: 61 PQQPQQPLL 69
QQ Q P L
Sbjct: 304 QQQLQPPPL 312
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/79 (48%), Positives = 45/79 (56%), Gaps = 10/79 (12%)
Query: 3 SQQQQQQLQQQQQQLQQ--LQQQQLQQQQLQQQQLLQLQQ-LLQQSPPQAPLPMAVSRGL 59
+Q QQQ L+QQQ QLQQ L QQQ Q QQ QQQQLLQ QQ LQQ Q P L
Sbjct: 260 AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPP-------PL 312
Query: 60 PPQQPQQPLLNLQGTNSAS 78
P++ ++ L L + S
Sbjct: 313 EPEEEEEVELELMPVDLGS 331
Score = 42.4 bits (98), Expect = 0.002
Identities = 42/111 (37%), Positives = 49/111 (44%), Gaps = 20/111 (18%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQL-------------QQQQLQQQQLLQLQQLLQQSPPQAP 50
QQ QQ QQQ QLQQ + Q + QQQQLQ QQ+ Q QQ LQQ Q
Sbjct: 120 QQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQV-QEQQRLQQQQEQLQ 178
Query: 51 LPMAVSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGLDQ 99
A + + QQ Q Q LL LQ+ LLQQ + L Q
Sbjct: 179 TQQAQEQQVLQQQEQLQ----QQVQEQQLLQQQQEQLQQQQLLQQQEQLQQ 225
Score = 42.4 bits (98), Expect = 0.002
Identities = 31/74 (41%), Positives = 45/74 (60%), Gaps = 6/74 (8%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQ---QQQLQQ--QQLLQLQQLLQQSPPQAPLPMAVSRG 58
+QQ+Q+L++QQ+ +Q +Q+QLQ Q++LQQ QQL Q QQ L+Q Q L V G
Sbjct: 336 EQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLEL-TPVELG 394
Query: 59 LPPQQPQQPLLNLQ 72
Q+ Q L +Q
Sbjct: 395 AQQQEVQLELTPVQ 408
Score = 40.8 bits (94), Expect = 0.006
Identities = 42/111 (37%), Positives = 48/111 (43%), Gaps = 20/111 (18%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQ----LQQQQLQ--QQQLLQLQQLLQQS------PPQAPL 51
Q +QQ QQQ Q +QLQQ Q LQQQ Q QQQL QLQQ QS P+ L
Sbjct: 93 QLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQL 152
Query: 52 --------PMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQL 94
P V QQ Q+ L Q L LQ+ + QQL
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQL 203
Score = 40.0 bits (92), Expect = 0.010
Identities = 81/377 (21%), Positives = 144/377 (38%), Gaps = 40/377 (10%)
Query: 12 QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNL 71
Q++ QLQQL+QQ QQQ Q +QL Q P P + P Q QQ L L
Sbjct: 86 QRELQLQQLEQQPEPQQQPQHEQL------------QQPQPHLELQQQPQQDGQQQLSQL 133
Query: 72 QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPG 131
Q S+ + + L+ Q Q L P + L L +
Sbjct: 134 QQEKHQSVHHQELKPELQLMHQQQQL----QPQQVQEQQRLQQQQEQLQTQQ--AQEQQV 187
Query: 132 LAAPSLTPPQLATPN-LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSS 190
L Q+ LQQ Q +Q LL + QF + Q+Q +
Sbjct: 188 LQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE---QLQQQQF----QQQQEQLQQQQQ 240
Query: 191 TTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE 250
++ Q ++ + + ++ E + + Q L E + ++++ +
Sbjct: 241 LLLLQQQGQLQQQLLQQQQ--AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQ- 297
Query: 251 PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPR 310
+ +L ++L+ P E E +++++ P + + + + E Q L R
Sbjct: 298 --QQEQLQQQQLQ--PPPLEPEEEEEVELELMP---VDLGSEQELEQQRQELERQQELER 350
Query: 311 FQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 370
Q Q+Q ++Q + Q + Q Q Q++ Q + +P L QQ++VQ +L
Sbjct: 351 -QQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLEL---TP 406
Query: 371 PQKQVQPQVQPQAHSQG 387
Q ++Q ++ P A G
Sbjct: 407 VQPELQLELVPAAGGGG 423
Score = 39.7 bits (91), Expect = 0.013
Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 4/66 (6%)
Query: 4 QQQQQQLQQQ-QQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
QQ+Q+QLQ + Q++LQQL+QQ QQQQ +QQ +QL+ + Q V L P
Sbjct: 351 QQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQ---QQEVQLELTPV 407
Query: 63 QPQQPL 68
QP+ L
Sbjct: 408 QPELQL 413
Score = 37.7 bits (86), Expect = 0.048
Identities = 19/47 (40%), Positives = 33/47 (70%), Gaps = 5/47 (10%)
Query: 7 QQQLQQQQQQLQQLQQQQLQQQQLQ-----QQQLLQLQQLLQQSPPQ 48
+Q+L+QQ+Q+L++ Q+ + QQ+Q Q Q++L QL+Q L+Q Q
Sbjct: 332 EQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQ 378
Score = 31.6 bits (70), Expect = 3.5
Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 47/175 (26%)
Query: 4 QQQQQQLQQQQQQLQQLQQQ----------------------------------QLQQQQ 29
QQQQQ LQQQQ+QLQQ Q Q + QQ+
Sbjct: 289 QQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQEL 348
Query: 30 LQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRAL 89
+QQ+ QLQ LQ+ Q + + L QQ Q +Q + L + L
Sbjct: 349 ERQQEQRQLQLKLQEELQQ------LEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQL 402
Query: 90 LLQQLQGLDQFAMPPATYDTAGLT--MPTATLGNLRGYG-----MASPGLAAPSL 137
L +Q Q + PA P A + GY M P +AAP++
Sbjct: 403 ELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQELMVLPAVAAPAV 457
>gi|148612879 polyhomeotic like 3 [Homo sapiens]
Length = 995
Score = 83.2 bits (204), Expect = 1e-15
Identities = 156/658 (23%), Positives = 236/658 (35%), Gaps = 108/658 (16%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
Q QQ+ QQQ L LQQQ L QL L A + ++S G P P
Sbjct: 75 QYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSL----------AAVQASLSSGRPSTSP 124
Query: 65 QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT--AGLTMPTATLGNL 122
+ + S+ + A L+ + Q T T G T PT T
Sbjct: 125 TGSVTQQSSMSQTSINLSTSPTPAQLISRSQA-SSSTSGSITQQTMLLGSTSPTLTASQA 183
Query: 123 RGYGMASPGLAAPSLTP-------PQLATPNLQQFFPQATR-QSL-LGPPPVGVPMNPSQ 173
+ Y A + P+ T P +++ + AT+ Q+L L +GV
Sbjct: 184 QMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGV------ 237
Query: 174 FNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE------ 227
+ S P K + S T ++ + + + PE +++ P +++
Sbjct: 238 LSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRT 297
Query: 228 ---DQDLPPC------PEDIAKEKRTPAPEPEPCEAS--ELPAKRLRSSEEP------TE 270
Q + P P + K ++ P P P + S +L ++ + +P T+
Sbjct: 298 SSIHQLIAPASYSPIQPHSLIKHQQIPLHSP-PSKVSHHQLILQQQQQQIQPITLQNSTQ 356
Query: 271 KEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI 330
PP Q + Q P Q+ P +++ P AQ P
Sbjct: 357 DPPPSQHCIPLQNHGLPPAPSNAQSQHCSP--IQSHPSPLTVSPNQSQSAQQSVVVSPPP 414
Query: 331 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQ---- 386
P + +Q P + Q P LV Q P LQQ Q Q Q+ +H
Sbjct: 415 PHSPSQ-SPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPAS 473
Query: 387 -----GPRQVQL-----QQEAEPLKQVQPQVQ---------PQAHSQPPRQV-QLQLQKQ 426
GP Q QQ P Q +Q PQ + PP Q+ L LQ
Sbjct: 474 PVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSM 533
Query: 427 VQTQTYPQVHTQAQPSVQ-----PQEHPPAQVSVQPPEQTHEQPHT---QPQVSLLAPEQ 478
Q P++ +Q Q VQ +E P A+ VQ P QT P T QV AP
Sbjct: 534 QSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVD 593
Query: 479 TPVVVH---VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 535
PVV VC EMP ++ E M++T P P S + VG E+
Sbjct: 594 PPVVYQVEDVCEEEMPEESDEC-VRMDRTPPPP-----------TLSPAAITVGRGEDLT 641
Query: 536 REMPGV----WGAGGSLKVTILQSSDSRAFSTVPLTP--VPRPSDSVSSTPAATSTPS 587
E P + A S+ ++++S + +VP P +P + +ST +S PS
Sbjct: 642 SEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPS 699
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 81.6 bits (200), Expect = 3e-15
Identities = 135/528 (25%), Positives = 194/528 (36%), Gaps = 69/528 (13%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ--SPPQAPLP----MAVSR 57
QQQQQQ QQQQQQ QQ QQQQLQ + QQ Q Q Q + Q +P Q P+P S
Sbjct: 265 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSG 324
Query: 58 GLPPQQPQQPLLNL---QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTM 114
L P Q L + QG A L G M Q+ L + + PP Y
Sbjct: 325 ALQPPPAQGSLGTMTANQGWKKAP-LPGPMQQQLQARPSLATVQTPSHPPPPYPFGS--- 380
Query: 115 PTATLGNLRGYGMASPG----------LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164
A+ + M++PG PS P L P+L P ++ S P
Sbjct: 381 QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSP 440
Query: 165 VGVP-MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
P +N +Q + R PQ P S + V+ + PP +P
Sbjct: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQP--VSSPGRNPMVQQGNVPPNFMVMQQQPPN 498
Query: 224 DTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 283
P Q L P + K P A + ++ T PG Q
Sbjct: 499 QGP--QSLHPGLGGMPKRL------PPGFSAGQANPNFMQGQVPSTTATTPGN-SGAPQL 549
Query: 284 QARMTVPK---QTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQ-----PRIPSTDT 335
QA V Q P + QP ++ + + +Q P++ ++
Sbjct: 550 QANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNM 609
Query: 336 QVQPKLQKQAQTQTSPEHLVLQQKQV----------QPQLQQEAEPQKQVQPQVQPQAHS 385
Q QP+ +Q + +V Q Q+ P + A+ Q Q V P + +
Sbjct: 610 QGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQN 669
Query: 386 QGPRQVQLQQEAEPLKQVQPQVQPQAHSQ---PPRQVQLQ---LQKQVQTQ----TYPQV 435
GP ++ + L Q PQ+ H+Q P QV LQ + +Q+ T Q
Sbjct: 670 LGPSPQRMTPPKQMLSQQGPQMM-APHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQF 728
Query: 436 HTQAQPSVQPQEHPPAQV--SVQPPEQTHEQPHTQPQVSLLAPEQTPV 481
+TQ Q +V P PAQ+ P Q + T + P+Q PV
Sbjct: 729 NTQNQSNVMP---GPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPV 773
Score = 59.3 bits (142), Expect = 2e-08
Identities = 127/537 (23%), Positives = 185/537 (34%), Gaps = 109/537 (20%)
Query: 1 MFSQQQQ---QQLQQQQQQLQQLQQQQLQQQQL---QQQQLLQLQQLLQQ-----SPPQA 49
M Q QQ QL QQ+ Q Q +QQQ Q +L QL+ Q +PP
Sbjct: 609 MQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQ 668
Query: 50 PLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSM-LQRALLLQQLQGLDQFAMPPATYD 108
L + R PP+Q +L+ QG + N M Q +LLQQ ++Q
Sbjct: 669 NLGPSPQRMTPPKQ----MLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQI-------- 716
Query: 109 TAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLA---TPNLQQFFPQATRQSLLGPPPV 165
M GN + + + P P Q+ TPN+Q Q T Q P
Sbjct: 717 -----MTNQMQGNKQQFNTQNQSNVMPG--PAQIMRGPTPNMQGNMVQFTGQMSGQMLPQ 769
Query: 166 GVPMNPSQFNLSGRNPQ-----------KQARTSSSTTPNRKDSSSQTMP----VEDKSD 210
P+N S + G Q Q +TT N S SQ MP +
Sbjct: 770 QGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMV 829
Query: 211 PP-----EGSEEAAE-----------PRMDTPEDQDLPPCPED----IAKEKRTPAPEPE 250
PP +G+ + P P + C ++ + K+ +P
Sbjct: 830 PPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMS-CGQNPGFPVNKDVTLTSPLLV 888
Query: 251 PCEASELPAKR--LRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL 308
S++ A + + + T P + K P+ + + TPD P LE
Sbjct: 889 NLLQSDISAGHFGVNNKQNNTNANKPKK---KKPPRKKKNSQQDLNTPDTRPAGLEEAD- 944
Query: 309 PRFQPRVLQVQAQVQSQTQPRIPSTDT----------------QVQPKLQKQAQTQTSPE 352
QP + Q + P++P Q+ P+L + P
Sbjct: 945 ---QPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPP 1001
Query: 353 HLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAH 412
Q+Q QPQL Q+ +P QPQ Q Q Q + L + +P K V+ V H
Sbjct: 1002 -----QQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDP-KSVRLPVSQNVH 1055
Query: 413 SQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQP 469
PPR +Q P + + P V PA V P +Q P P
Sbjct: 1056 --PPRG-----PLNPDSQRMPMQQSGSVP-VMVSLQGPASVPPSPDKQRMPMPVNTP 1104
Score = 52.0 bits (123), Expect = 2e-06
Identities = 63/270 (23%), Positives = 99/270 (36%), Gaps = 34/270 (12%)
Query: 222 RMDTPEDQDLPPCPEDIAKEKRTPAPEPE-------PCEASELPAKRLRSSEEPTEKEPP 274
RM+ P +PP +++ P P PE P S+ L + P
Sbjct: 175 RMNNPATVMIPP-GGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPS 233
Query: 275 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334
G L P ++V +Q + P+ Q + Q Q Q Q Q Q +
Sbjct: 234 GSLAPPHHPMQPVSVNRQMNPAN----------FPQLQQQQQQQQQQQQQQQQQQQQQQQ 283
Query: 335 TQVQPKLQKQAQTQ----TSPEHLVLQQKQVQP---QLQQEAEPQKQVQPQVQPQAHSQG 387
Q+Q + +Q Q Q P+ Q V P QL A Q + +QG
Sbjct: 284 QQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQG 343
Query: 388 PRQVQLQQEAEPLKQVQPQ---VQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQ---P 441
++ L + Q +P VQ +H PP Q Q T +PQ+ Q P
Sbjct: 344 WKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHT-NFPQMSNPGQFTAP 402
Query: 442 SVQPQEHPPAQV--SVQPPEQTHEQPHTQP 469
++ + P++V +Q P T++ P + P
Sbjct: 403 QMKSLQGGPSRVPTPLQQPHLTNKSPASSP 432
Score = 51.2 bits (121), Expect = 4e-06
Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 16/155 (10%)
Query: 331 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQ 390
P + ++QP+ + A + + L+ +QQ++ P + P P P
Sbjct: 197 PGPNPELQPRTPRPASQSDAMDPLLSGL-----HIQQQSHPSGSLAPPHHPMQ----PVS 247
Query: 391 VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTY-PQVHTQAQP-SVQPQEH 448
V Q Q+Q Q Q Q Q +Q Q Q Q+Q Q Q PQ H Q QP ++PQ
Sbjct: 248 VNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFT 307
Query: 449 PPAQVSVQP-----PEQTHEQPHTQPQVSLLAPEQ 478
P QV V P P + P Q + + Q
Sbjct: 308 APTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQ 342
Score = 48.9 bits (115), Expect = 2e-05
Identities = 76/291 (26%), Positives = 112/291 (38%), Gaps = 34/291 (11%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL-PPQ 62
QQ Q QL QQQQ Q Q QQQQ QQQ ++ L ++QQ P LP VS+ + PP+
Sbjct: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML--MMQQDPKSVRLP--VSQNVHPPR 1058
Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTAT-LGN 121
P LN +GS+ ++ LQG A P + D + MP T LG+
Sbjct: 1059 GP----LNPDSQRMPMQQSGSV----PVMVSLQGP---ASVPPSPDKQRMPMPVNTPLGS 1107
Query: 122 LRGYGMASPGLAAPSLTP-PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
+ PS +P ++A+ P+A+ G VP P+
Sbjct: 1108 NSRKMVYQESPQNPSSSPLAEMAS------LPEAS-----GSEAPSVPGGPNNMPSHVVL 1156
Query: 181 PQKQ-ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239
PQ Q T P+ ++ P + + S P + P P P +
Sbjct: 1157 PQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRAS 1216
Query: 240 KE---KRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 287
+TP P E SE+ R + PP Q+ + P+ +
Sbjct: 1217 PRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPP-QINIPLPPRPNL 1266
Score = 47.8 bits (112), Expect = 5e-05
Identities = 106/495 (21%), Positives = 181/495 (36%), Gaps = 66/495 (13%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-QLQQLLQQSPPQ-----APLPMA 54
M SQQ Q + Q + Q LQQ + +Q + Q+Q QQ Q P P
Sbjct: 683 MLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQ 742
Query: 55 VSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGLDQFAMPPATYDTAGL 112
+ RG P Q ++ G S +L G + + +QG P+ +
Sbjct: 743 IMRG-PTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQH 801
Query: 113 TMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQS-------LLGPPPV 165
P T N P + S+ + P++Q + + P
Sbjct: 802 GDPATTANNDVSLSQMMPDV---SIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFS 858
Query: 166 GVPMNPSQFNLSGRNP----QKQARTSSSTTPN--RKDSSSQTMPVEDKSDPPEGSEEAA 219
G P N +Q + G+NP K +S N + D S+ V +K + + A
Sbjct: 859 GAP-NGNQMS-CGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNK----QNNTNAN 912
Query: 220 EPRMDTPEDQDLPPCPEDIAKEKRTPAPEP---EPCEASELPAKRLRSSEEPTEKEPPGQ 276
+P+ P P ++ ++ TP P E + LP ++ + + K P
Sbjct: 913 KPKKKKP-----PRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLP--- 964
Query: 277 LQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQ 336
+ +P + P + + +P L V P QP Q Q Q+ Q QP PS
Sbjct: 965 -EFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPS---- 1019
Query: 337 VQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGP-----RQV 391
QP+ Q+Q Q QQ+Q+ L + +P+ P Q +GP +++
Sbjct: 1020 -QPQSQQQQQ----------QQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRM 1068
Query: 392 QLQQEAEPLKQVQPQVQPQAHSQPPRQ-VQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPP 450
+QQ V Q P +Q + + + + + + V+ ++ + P P
Sbjct: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQN--PSSSPL 1126
Query: 451 AQVSVQPPEQTHEQP 465
A+++ P E P
Sbjct: 1127 AEMASLPEASGSEAP 1141
Score = 46.6 bits (109), Expect = 1e-04
Identities = 49/166 (29%), Positives = 69/166 (41%), Gaps = 32/166 (19%)
Query: 339 PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAE 398
P+LQ+Q Q Q QQ+Q Q Q QQ+ + Q+Q+Q + Q Q P+ ++ Q A
Sbjct: 258 PQLQQQQQQQ--------QQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAP 309
Query: 399 PLKQVQP---QVQPQAHSQPPRQVQL------QLQKQVQTQTYPQVHTQAQPS---VQPQ 446
V P Q+ A PP Q L Q K+ Q QA+PS VQ
Sbjct: 310 TQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTP 369
Query: 447 EHPP----------AQVSVQPPEQTHEQPHTQPQVSLL--APEQTP 480
HPP +Q P+ ++ T PQ+ L P + P
Sbjct: 370 SHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP 415
Score = 45.1 bits (105), Expect = 3e-04
Identities = 89/437 (20%), Positives = 132/437 (30%), Gaps = 98/437 (22%)
Query: 140 PQLATPNLQQFFPQATRQSLLGPP-----PVGV--PMNPSQFNLSGRNPQKQARTSSSTT 192
P L+ ++QQ Q+ L PP PV V MNP+ F + Q+Q +
Sbjct: 219 PLLSGLHIQQ---QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQ 275
Query: 193 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP------- 245
++ Q + + + P+ P +PP + P
Sbjct: 276 QQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSL 335
Query: 246 -----------APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ 294
AP P P + L + + P+ PP + QA P+ +
Sbjct: 336 GTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSN 395
Query: 295 T--------------PDLLPEALEAQVL----PRFQPRVLQVQA--------QVQSQTQP 328
P +P L+ L P P Q + Q Q Q P
Sbjct: 396 PGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGP 455
Query: 329 RIPSTDTQVQ--------PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQ 380
R P + Q P Q P + ++ Q+Q Q Q P P+
Sbjct: 456 RPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRL 515
Query: 381 PQAHSQGPRQVQLQQEAEP-----------LKQVQ---------------PQVQPQAHSQ 414
P S G Q P Q+Q PQ Q Q
Sbjct: 516 PPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHG 575
Query: 415 PPRQVQLQL--------QKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 466
PP +Q L +Q T PQV+ QPQ+ PP+Q+ + Q
Sbjct: 576 PPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQG-QPQQGPPSQLMGMHQQIVPSQGQ 634
Query: 467 TQPQVSLLAPEQTPVVV 483
Q L P Q P+++
Sbjct: 635 MVQQQGTLNP-QNPMIL 650
Score = 43.5 bits (101), Expect = 9e-04
Identities = 31/117 (26%), Positives = 48/117 (41%), Gaps = 7/117 (5%)
Query: 371 PQKQVQPQVQPQAHSQGPRQ------VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQ 424
P ++QP+ P+ SQ + +QQ++ P + P P RQ+
Sbjct: 199 PNPELQPRT-PRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANF 257
Query: 425 KQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 481
Q+Q Q Q Q Q Q Q+ Q+ +PP+Q +Q + AP Q PV
Sbjct: 258 PQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPV 314
Score = 41.2 bits (95), Expect = 0.004
Identities = 125/593 (21%), Positives = 199/593 (33%), Gaps = 100/593 (16%)
Query: 3 SQQQQQQLQQQQQQLQQLQQQQ------------------------LQQQQLQQQQLLQL 38
SQ Q QQ QQQQQQ+ + Q Q+ +QQ + +
Sbjct: 1019 SQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPV 1078
Query: 39 QQLLQ------QSPPQAPLPMAVSRGL-----------PPQQP-QQPLLNL------QGT 74
LQ SP + +PM V+ L PQ P PL + G+
Sbjct: 1079 MVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGS 1138
Query: 75 NSASLLNG--SMLQRALLLQ-QLQGLDQFAMPPATYDTAGLTMPTATLGNL-RGYGMASP 130
+ S+ G +M +L Q QL P T G T + +L +G P
Sbjct: 1139 EAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP 1198
Query: 131 GLAAPSLT----PPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN---PQK 183
+AAP+ T P A+P + ++PQ P + ++P + N S PQ
Sbjct: 1199 NVAAPTQTSRPKTPNRASP--RPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQI 1256
Query: 184 QARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP-RMDTPEDQDLPPCPEDIAKEK 242
NR P K+ S P TP+ L + K+
Sbjct: 1257 NIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQS 1316
Query: 243 RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDL---- 298
+ A + AS ++R PG+ KA ++T+ QT L
Sbjct: 1317 NSGATK----RASPSNSRRSSPGSSRKTTPSPGRQNSKA---PKLTLASQTNAALLQNVE 1369
Query: 299 LPEALEAQVLPRFQPRV---------LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 349
LP + P P V L Q S D + + + + Q
Sbjct: 1370 LPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQN 1429
Query: 350 SPEHLVLQQKQVQPQLQQEAEPQKQVQPQV-QPQAHSQGPRQVQLQQEAEPLKQVQPQVQ 408
S Q ++ Q ++ +A P ++V+ V + Q+ G Q ++P K +
Sbjct: 1430 S------QSRKEQVNIELKAVPAQEVKMVVPEDQSKKDG-------QPSDPNKLPSVEEN 1476
Query: 409 PQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 468
S R+ L + + P V T P + E P VS + ++ P Q
Sbjct: 1477 KNLVSPAMREAPTSLSQLLDNSGAPNV-TIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQ 1535
Query: 469 PQVSLLAPEQTPVVVH---VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEI 518
S P + + H +C + P+ E + ++P + VS I
Sbjct: 1536 DLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSI 1588
Score = 39.3 bits (90), Expect = 0.017
Identities = 110/513 (21%), Positives = 173/513 (33%), Gaps = 102/513 (19%)
Query: 20 LQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASL 79
+ QQ + Q L +Q QQ PP M + + + P Q Q ++ QGT +
Sbjct: 591 MNNQQAGTSGVPQVNLSNMQGQPQQGPPSQL--MGMHQQIVPSQGQ--MVQQQGTLNPQ- 645
Query: 80 LNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAP---- 135
N +L RA L+ Q Q + + P+ LG SP P
Sbjct: 646 -NPMILSRAQLMPQGQMM--------------VNPPSQNLG-------PSPQRMTPPKQM 683
Query: 136 -SLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQ-------ART 187
S PQ+ P+ Q PQ P + N Q N N Q Q A+
Sbjct: 684 LSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQI 743
Query: 188 SSSTTPNRKDSSSQ-TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPA 246
TPN + + Q T + + P +G + ++ + Q L P P
Sbjct: 744 MRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRP-----------PG 792
Query: 247 PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQ 306
P P + PA + ++ P +Q Q M P +A++
Sbjct: 793 PSPHMAQQHGDPATTANNDVSLSQMMPDVSIQ-----QTNMVPPHV--------QAMQGN 839
Query: 307 VLP--RFQPRVLQVQA---------QVQSQTQPRIPSTD--TQVQPKLQKQAQTQTSPEH 353
F + A Q+ P P T P L Q+ S H
Sbjct: 840 SASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGH 899
Query: 354 LVLQQKQVQPQLQQEAEPQKQVQPQV----QPQAHSQGPRQVQLQQEAEP---------L 400
+ KQ + P+K+ P+ Q ++ R L++ +P L
Sbjct: 900 FGVNNKQNNTNANK---PKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINL 956
Query: 401 KQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQ-PQEHP----PAQVSV 455
P++ P+ ++PP ++++ Q PQ+ P Q PQ+ P P Q
Sbjct: 957 DNSGPKL-PEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP 1015
Query: 456 QPPEQTHEQPHTQPQ---VSLLAPEQTPVVVHV 485
PP Q Q Q Q + +L +Q P V +
Sbjct: 1016 PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRL 1048
Score = 38.5 bits (88), Expect = 0.028
Identities = 61/305 (20%), Positives = 104/305 (34%), Gaps = 31/305 (10%)
Query: 18 QQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSA 77
Q ++Q+ LQQ QL+Q Q P Q P P + PP P QP Q
Sbjct: 976 QPVEQRPLQQ---MPPQLMQHVAPPPQPPQQQPQPQLPQQQQPP-PPSQPQSQQQQQQQQ 1031
Query: 78 SLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSL 137
++ M+Q+ +L P + MP G++ L P+
Sbjct: 1032 QMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSV----PVMVSLQGPAS 1087
Query: 138 TPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQ----FNLSGRNPQKQARTSSSTTP 193
PP +P+ Q+ P PV P+ + + S +NP ++ P
Sbjct: 1088 VPP---SPDKQRM-----------PMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLP 1133
Query: 194 NRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCE 253
S + ++P + P + M P+ P A ++ P
Sbjct: 1134 EASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSH 1193
Query: 254 ASELPAKRLRSSEEPTEKEPPGQLQVKA-QPQARMTVPKQTQTPD--LLPEALEAQVLPR 310
P + + + + + P + + PQ P T+ + L PE L A +
Sbjct: 1194 GHHFP--NVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGL 1251
Query: 311 FQPRV 315
F P++
Sbjct: 1252 FPPQI 1256
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 81.3 bits (199), Expect = 4e-15
Identities = 83/302 (27%), Positives = 113/302 (37%), Gaps = 38/302 (12%)
Query: 198 SSSQTMPVEDKSDPPEGSEEAAEPRM------DTPEDQDLPPCPEDIAKEKRTPAPEPEP 251
++ +T P +DP +E + PR P LP P +++ T P P+
Sbjct: 343 AAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQA 402
Query: 252 CEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL--EAQVLP 309
+S P L S +P + PP Q + Q + P QTP + L +AQ P
Sbjct: 403 AGSSNQPGL-LASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATP 461
Query: 310 RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA 369
+ Q ++ Q Q Q Q P Q P QQ+Q Q Q Q
Sbjct: 462 QHQQQLFLKQQQQQQQPPP------------------AQQQPAGTFYQQQQAQTQQFQAV 503
Query: 370 EPQKQVQPQVQPQAHSQGPRQVQL------QQEAEPLKQVQPQVQPQAHSQP--PRQVQL 421
P Q Q SQG Q QL QQ+ + +Q Q Q+ H Q +Q L
Sbjct: 504 HPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAAL 563
Query: 422 QLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSV--QPPEQTHEQPHTQPQ-VSLLAPEQ 478
Q + + PQ A P P + P Q V QP QT P Q Q V L P
Sbjct: 564 QQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPS 623
Query: 479 TP 480
+P
Sbjct: 624 SP 625
Score = 54.3 bits (129), Expect = 5e-07
Identities = 70/305 (22%), Positives = 110/305 (36%), Gaps = 54/305 (17%)
Query: 162 PPPVGVPMNPSQFNLSGRNPQKQAR-------TSSSTTPNRKDSSSQT------MPVEDK 208
P P +P + + Q +AR T +S P ++ + QT +P++
Sbjct: 328 PIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPA 387
Query: 209 ---------SDPPEGSEEAAEPRMDTPEDQDLP------PCPEDIAKEKRTP-APEPEPC 252
PP+ + + +P + Q P P P+ AK+ + P P+ P
Sbjct: 388 LTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPS 447
Query: 253 -EASELPAKRLRSSEE----------------PTEKEPPGQL--QVKAQPQARMTVPKQT 293
+A LPA+ + + P +++P G Q +AQ Q V T
Sbjct: 448 TQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPAT 507
Query: 294 QTPDL--LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSP 351
Q P + P + + Q Q Q Q Q Q + +T Q + +QA Q P
Sbjct: 508 QQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKP 567
Query: 352 EHLVLQQKQVQP----QLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQV 407
QQ Q QP Q EP Q + QP+ + P VQ Q+ P+
Sbjct: 568 TMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKT 627
Query: 408 QPQAH 412
Q H
Sbjct: 628 QRAGH 632
Score = 53.5 bits (127), Expect = 9e-07
Identities = 69/238 (28%), Positives = 87/238 (36%), Gaps = 59/238 (24%)
Query: 234 CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
CP + PA PEP +ASE AK K QP+AR+T P T
Sbjct: 319 CPIPNVQNSPIPAKLPEPVKASEAAAK-------------------KTQPKARLTDPIPT 359
Query: 294 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
E + PR +P+ QTQP Q +K+A Q P+
Sbjct: 360 T---------ETSIAPRQRPKA--------GQTQPNPGILPIQPALTPRKRATVQPPPQ- 401
Query: 354 LVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHS 413
QP L PQ +PQA P Q Q +A+ QPQ P
Sbjct: 402 --AAGSSNQPGLLASV-------PQPKPQAP---PSQPLPQTQAK-----QPQAPPTPQQ 444
Query: 414 QPPRQVQ-LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQ 470
P Q Q L Q Q Q Q+ + Q Q Q+ PPAQ QP ++Q Q Q
Sbjct: 445 TPSTQAQGLPAQAQATPQHQQQLFLKQQQ--QQQQPPPAQ--QQPAGTFYQQQQAQTQ 498
Score = 50.8 bits (120), Expect = 6e-06
Identities = 31/67 (46%), Positives = 34/67 (50%), Gaps = 6/67 (8%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQA------PLPMAVSR 57
QQ Q QQQQQ QQ QQQQ L QQQL+ Q LQQ P A P P A +
Sbjct: 525 QQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQ 584
Query: 58 GLPPQQP 64
P Q+P
Sbjct: 585 PAPAQEP 591
Score = 41.2 bits (95), Expect = 0.004
Identities = 68/237 (28%), Positives = 89/237 (37%), Gaps = 33/237 (13%)
Query: 5 QQQQQLQQQQQQLQQLQQQQ------LQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58
QQQ L+QQQQQ Q QQ QQQQ Q QQ + QQ P A P+ G
Sbjct: 464 QQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQ-PAIAQFPVVSQGG 522
Query: 59 LPP-------QQPQQPLLNLQGTNSASLLNGS--MLQRALLL--------QQLQGLDQFA 101
QQ QQ Q A+ L+ M Q+A L QQ Q A
Sbjct: 523 SQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAA 582
Query: 102 MPPATYDTAGLTMPTATLGNLRGY-GMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLL 160
PA + P ++ A G SLTPP ++P Q+ + +
Sbjct: 583 PQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPP--SSPKTQRAGHRRILSDVT 640
Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSS--TTPNRKDSSSQTMPVEDKSDPPEGS 215
GVP + S L + S S TTP+ +SQ ++ +P EGS
Sbjct: 641 HSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQ----QNVYNPSEGS 693
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 81.3 bits (199), Expect = 4e-15
Identities = 101/382 (26%), Positives = 136/382 (35%), Gaps = 52/382 (13%)
Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 220
GPPP+ P P F + R P R P D + MP PP G
Sbjct: 42 GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96
Query: 221 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK 280
P P +PP P + P P A PA K P G++
Sbjct: 97 PPFMPPPMSSMPPPPGMMF------PPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150
Query: 281 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
AR T+ PD + ++++ P +L QAQVQ+Q Q Q Q +
Sbjct: 151 ---NARTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQ-----AQAQAQAQ 196
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
Q QAQ Q + Q Q Q Q Q +A+ Q Q Q Q Q QA +Q QVQ Q +A+ +
Sbjct: 197 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV 256
Query: 401 -------KQVQPQVQPQAHSQPPRQ-----------VQLQLQKQVQTQTYPQVHTQAQPS 442
P V S P Q Q QT + A P+
Sbjct: 257 GASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPT 316
Query: 443 VQPQEHPPAQVSVQPPEQTHEQ------PHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 496
V P VQ Q H Q PH+ PQ + P PV+V + +P +
Sbjct: 317 VSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIP 376
Query: 497 AGG---GMEKTLPEPVGTQVSM 515
G GM + + QV++
Sbjct: 377 LPGVLPGMAPPIVPMIHPQVAI 398
Score = 70.1 bits (170), Expect = 9e-12
Identities = 82/297 (27%), Positives = 107/297 (36%), Gaps = 51/297 (17%)
Query: 198 SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASEL 257
+ Q + + PP P M PP P + R P P P P
Sbjct: 22 AQQQALRFRGPAPPPNAVMRGPPPLMR-------PPPPFGMM---RGPPPPPRP------ 65
Query: 258 PAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP---RFQPR 314
P R PPG + P P Q P +P + + P F P
Sbjct: 66 PFGRPPFDPNMPPMPPPGGIP---PPMG----PPHLQRPPFMPPPMSSMPPPPGMMFPPG 118
Query: 315 VLQVQAQVQSQTQPRIPSTDT-QVQPKLQK------QAQTQ----TSPEHL-VLQQKQVQ 362
+ V A P +P T+ V+ K A+T+ T P+ + V+QQ ++
Sbjct: 119 MPPVTAP----GTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELT 174
Query: 363 PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ 422
P L +A+ Q Q Q Q Q QA +Q Q Q Q +A Q Q Q Q QA +Q Q Q Q
Sbjct: 175 PMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQA----QAQAQAQAQAQAQAQAQAQAQ 230
Query: 423 LQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 479
Q Q Q Q QV Q Q VQ Q V P + P S P T
Sbjct: 231 AQAQAQAQAQAQVQAQVQAQVQAQ-----AVGASTPTTSSPAPAVSTSTSSSTPSST 282
Score = 47.0 bits (110), Expect = 8e-05
Identities = 86/442 (19%), Positives = 134/442 (30%), Gaps = 59/442 (13%)
Query: 26 QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84
+ ++ +L QQ + AP P AV RG PP +P P ++G
Sbjct: 10 ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPR----- 64
Query: 85 LQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLAT 144
F PP +D MP G P + P L P
Sbjct: 65 -------------PPFGRPP--FDPNMPPMPPP--------GGIPPPMGPPHLQRPPFMP 101
Query: 145 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 204
P + P G PPV P P+ P + + TP+ K
Sbjct: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPAL-------PPTEEIWVENKTPDGKVYYYNART 154
Query: 205 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
E P+G + + + TP + + A +A + A+
Sbjct: 155 RESAWTKPDGVKVIQQSEL-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQ 212
Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
++ + + Q Q +AQ QA+ Q Q + ++AQ + P V +
Sbjct: 213 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVST 272
Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
T PS+ T AQT ++P Q Q A P V
Sbjct: 273 STSSSTPSSTTSTTTTATSVAQTVSTP----TTQDQTPSSAVSVATPTVSVS-------- 320
Query: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQV---------QLQLQKQVQTQTYPQV 435
+ P +Q +P Q P P + QP + ++ P V
Sbjct: 321 TPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGV 380
Query: 436 HTQAQPSVQPQEHPPAQVSVQP 457
P + P HP ++ P
Sbjct: 381 LPGMAPPIVPMIHPQVAIAASP 402
Score = 40.0 bits (92), Expect = 0.010
Identities = 77/311 (24%), Positives = 106/311 (34%), Gaps = 44/311 (14%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62
Q Q Q Q Q Q Q Q Q Q Q+Q Q Q+Q Q + S P P AVS
Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277
Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNL 122
P T S + S+ Q A+ AT T ++ P T +
Sbjct: 278 TP-------SSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVAT-PTVSVSTPAPTATPV 329
Query: 123 RGYGMASPGLAAP----SLTPPQLATPNLQQFFPQATRQSLLGPP-----------PVGV 167
+ P P S+ P A P R L G P P V
Sbjct: 330 QTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIV 389
Query: 168 PMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE 227
PM Q ++ T+ S K + +T +++ E E + E
Sbjct: 390 PMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRT-----LESTWEKPQELKE 444
Query: 228 DQDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEKEPPGQLQV 279
+ L E I + + P+ EP P E E P K ++ EE TE+E Q
Sbjct: 445 KEKL---EEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQ--- 498
Query: 280 KAQPQARMTVP 290
KA+P A +P
Sbjct: 499 KAKPVATAPIP 509
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 77.8 bits (190), Expect = 4e-14
Identities = 86/315 (27%), Positives = 124/315 (39%), Gaps = 73/315 (23%)
Query: 5 QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54
Q QQQ+QQQQQQLQ++ QQQQ QQQQ QQQQ LQ Q +QQ P PQ P A
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285
Query: 55 VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAM 102
+ + L PP QPQQP + N S L + L+ Q L G +
Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Query: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGP 162
PP + A + + PP QQ Q + + +
Sbjct: 343 PPLKFVRAPMVVQ----------------------QPPVQPQVQQQQTAVQTAQAAQMVA 380
Query: 163 PPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPR 222
P V V Q SS +P ++ + Q+MP PP+ S + +P
Sbjct: 381 PGVQV-------------SQSSLPMLSSPSPGQQVQTPQSMP-----PPPQPSPQPGQPS 422
Query: 223 MDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 282
+ P P + P+P P+P + S + A+ ++ P+ PG L
Sbjct: 423 SQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS----PGPLNTPVN 474
Query: 283 PQARMTVPKQTQTPD 297
P + M+ +Q +
Sbjct: 475 PSSVMSPAGSSQAEE 489
Score = 77.0 bits (188), Expect = 7e-14
Identities = 101/365 (27%), Positives = 144/365 (39%), Gaps = 75/365 (20%)
Query: 275 GQLQVKAQPQARMTVPKQTQTPDLLPE--ALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS 332
G L QP + P T + P A+ + P+ Q ++ QV Q Q Q Q
Sbjct: 114 GSLGAMGQPMSLSGQPPPG-TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQ----Q 168
Query: 333 TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH-----SQG 387
Q Q LQ+Q Q Q + QQ +Q Q Q + Q+Q+Q Q Q Q H Q
Sbjct: 169 FQQQQQAALQQQQQQQQQ-QQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQN 227
Query: 388 PRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQE 447
+Q+Q QQ+ Q+Q Q Q Q +Q Q Q Q+Q Q P + QP +Q +
Sbjct: 228 QQQIQQQQQ-----QLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ---QPPMQQPQ 279
Query: 448 HPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP---------DAVEAG 498
PP+Q Q +Q H H QP P+Q PV + ++PP A
Sbjct: 280 PPPSQALPQQLQQMHHTQHHQPPPQ---PQQPPVAQNQPS-QLPPQSQTQPLVSQAQALP 335
Query: 499 GGMEKTLP-------------EPVGTQVSMEEIQNESACGLDVGECENRAREM--PGVWG 543
G M T P PV QV ++ ++A +A +M PGV
Sbjct: 336 GQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTA----------QAAQMVAPGVQV 385
Query: 544 AGGSLKVTILQSSDSRAFSTVPLTPVPRPS-----------DSVSSTPAAT-----STPS 587
+ SL + S + + + P P+PS +VSS PA + +PS
Sbjct: 386 SQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPS 445
Query: 588 KQALQ 592
Q Q
Sbjct: 446 PQPSQ 450
Score = 71.6 bits (174), Expect = 3e-12
Identities = 90/335 (26%), Positives = 121/335 (36%), Gaps = 26/335 (7%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQ---------LLQLQQLLQQSPPQAP--LP 52
QQQQQQ QQQQQ Q QQQQ QQQQ Q QQ ++Q QQ LQQ Q +
Sbjct: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIK 222
Query: 53 MAVSRGLPPQQPQQPL-----LNLQGTNSASLLNGSMLQRALLLQ---QLQGLDQFAMPP 104
+ QQ QQ L L LQ Q+AL Q Q + Q PP
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Query: 105 ATYDTAGLTMPTATLGNLRGYGMASPGLA--APSLTPPQLATPNLQQFFPQATRQSLLGP 162
+ L T + P +A PS PPQ T L Q L
Sbjct: 283 SQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Query: 163 PPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP----PEGSEEA 218
PP+ P PQ Q + ++ T + + V S P P ++
Sbjct: 343 PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQV 402
Query: 219 AEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQ 278
P+ P Q P + ++ + P P +S LP+ + S+ P P
Sbjct: 403 QTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFS 462
Query: 279 VKAQPQARMTV-PKQTQTPDLLPEALEAQVLPRFQ 312
V + V P +P +A E Q L + +
Sbjct: 463 VPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLK 497
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 74.3 bits (181), Expect = 5e-13
Identities = 90/346 (26%), Positives = 130/346 (37%), Gaps = 47/346 (13%)
Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 188
SPGL PQL P+ F A P VP + +Q PQ + S
Sbjct: 369 SPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQ-------PQTGSGAS 421
Query: 189 SSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPE 248
+ ++ S +Q + + RM + Q P + + + P
Sbjct: 422 RALPSWQEVSHAQQLK-------QIAANRQQHARMQQHQQQHQPT---NWSALPSSAGPS 471
Query: 249 PEPCEASELPAKRL-------RSSEEPTEKEPPGQLQV------KAQPQAR---MTVPKQ 292
P P ++P+ +SS P GQ +V KA P A+ + V Q
Sbjct: 472 PGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQ 531
Query: 293 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352
Q P L + P +PR Q T+P Q ++ +Q P
Sbjct: 532 -QKPQDLSRSFINNPHPAMEPR--------QGNTKPLFHFNSDQANQQMPSVLPSQNKPS 582
Query: 353 HLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAH 412
L Q+Q Q Q QQ+ + Q+Q Q Q Q Q Q Q QQ++ Q Q Q Q
Sbjct: 583 LLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----QQQQQSSISAQQQQQQQSSIS 637
Query: 413 SQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPP 458
+Q +Q Q Q Q+Q Q Q Q Q QPS QP + P+Q ++ P
Sbjct: 638 AQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683
Score = 61.6 bits (148), Expect = 3e-09
Identities = 45/98 (45%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQ-----QQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58
QQQQQQ QQQQQQ QQ QQQQ Q QQQ QQQ + QQ QQ Q +
Sbjct: 599 QQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQ 658
Query: 59 LPPQQPQQPLLNLQGTNSASLLNGSM-LQRALLLQQLQ 95
QQ Q Q S LL + LQ+ LLLQQ+Q
Sbjct: 659 QQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696
Score = 55.5 bits (132), Expect = 2e-07
Identities = 47/155 (30%), Positives = 65/155 (41%), Gaps = 8/155 (5%)
Query: 294 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
Q P +LP + +L Q + Q Q Q Q Q Q Q Q + Q+Q Q Q +
Sbjct: 570 QMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQQQS 622
Query: 354 LVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHS 413
+ Q+Q Q Q A+ Q+Q Q Q Q Q Q +Q Q QQ+ QP S
Sbjct: 623 SISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRS 682
Query: 414 QPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEH 448
P Q +L LQ Q+Q Q + Q + +H
Sbjct: 683 PLPLQQKLLLQ-QMQNQPIAGMGYQVSQQQRQDQH 716
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/66 (48%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Query: 6 QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65
QQQQ QQQQQQ QQ QQQQ QQQQ QQ Q L Q ++PLP+ + L Q
Sbjct: 639 QQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ-QKLLLQQMQN 697
Query: 66 QPLLNL 71
QP+ +
Sbjct: 698 QPIAGM 703
Score = 49.3 bits (116), Expect = 2e-05
Identities = 56/216 (25%), Positives = 83/216 (38%), Gaps = 25/216 (11%)
Query: 235 PEDIAKEK-RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
P+D+++ P P EP + + P S + A Q +P Q
Sbjct: 534 PQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQ--------------ANQQMPSVLPSQN 579
Query: 294 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
+ P LL + Q + Q + Q Q Q Q Q Q + Q Q+Q Q Q+S
Sbjct: 580 K-PSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSS--- 635
Query: 354 LVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH--SQGPRQVQLQQE--AEPLKQVQPQVQP 409
+ +Q Q Q QQ+ + Q+Q Q Q Q Q S P Q Q PL Q +
Sbjct: 636 --ISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQ 693
Query: 410 QAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQP 445
Q +QP + Q+ +Q + + V PS P
Sbjct: 694 QMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSP 729
Score = 41.6 bits (96), Expect = 0.003
Identities = 35/107 (32%), Positives = 41/107 (38%), Gaps = 6/107 (5%)
Query: 3 SQQQQQQL------QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS 56
S Q QQ+ Q + L QQQQ QQQQ QQQQ Q QQ QQ Q S
Sbjct: 564 SDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSS 623
Query: 57 RGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMP 103
QQ QQ ++ Q Q+ QQ Q + P
Sbjct: 624 ISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQP 670
Score = 39.3 bits (90), Expect = 0.017
Identities = 42/112 (37%), Positives = 54/112 (48%), Gaps = 23/112 (20%)
Query: 4 QQQQQQLQQQQ----QQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL 59
QQQQQQ QQQQ Q Q L Q L + L QQ L LQQ+ Q+ P A + VS
Sbjct: 654 QQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQM--QNQPIAGMGYQVS--- 708
Query: 60 PPQQPQQPLLNLQGTNSA-----------SLLNGSM-LQRALLLQQLQGLDQ 99
QQ +Q ++ G N+ + +G M Q++LL QQL G Q
Sbjct: 709 --QQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQ 758
Score = 36.2 bits (82), Expect = 0.14
Identities = 73/335 (21%), Positives = 120/335 (35%), Gaps = 42/335 (12%)
Query: 1 MFSQQQ--QQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58
M SQQ QQL ++Q LQ+ +Q QQ LQQQ L +++ PQ + +SR
Sbjct: 742 MNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKI----APQDQINRHLSRP 797
Query: 59 LPPQQPQ-------QPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAG 111
P + Q QP G +S LN + + ++ ++ T
Sbjct: 798 PPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRM 857
Query: 112 LTMPTATLGNLRGYG---MASPGLAAPSLTPPQLATP-NLQQFFPQATRQSLLGPPPVGV 167
++ TA + N+ YG P + + QL N +Q + PP +G
Sbjct: 858 PSLSTA-VQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGP 916
Query: 168 PMNPSQFNLS----GRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
N + G + Q + + S +S M + + P S+E +
Sbjct: 917 SNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQ 976
Query: 224 DTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSE-EPTEKEPPGQL----Q 278
+ + R P P ++ + + S + PP QL Q
Sbjct: 977 EALTSAGV-----------RFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQ 1025
Query: 279 VKAQPQARMTVPKQTQTP----DLLPEALEAQVLP 309
++ Q T+ QT P +L P L Q+LP
Sbjct: 1026 MRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILP 1060
Score = 35.4 bits (80), Expect = 0.24
Identities = 80/422 (18%), Positives = 154/422 (36%), Gaps = 62/422 (14%)
Query: 6 QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65
Q+ QQ +Q+ +QQ + QQ QQQ L S +P P + P Q
Sbjct: 428 QEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQ 487
Query: 66 Q-------PLLNLQGTNSASLLNGSMLQRALLLQQLQGLD-QFAMPPATYDTAGLTMPTA 117
Q P+ + G + S + + + +A Q LD P + + P
Sbjct: 488 QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNP-- 545
Query: 118 TLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLS 177
P++ P Q T L F Q + P + PS + +
Sbjct: 546 ----------------HPAMEPRQGNTKPLFHFNSDQANQQM--PSVLPSQNKPSLLHYT 587
Query: 178 GRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPED 237
+ Q+Q + ++ Q + + S + + + +
Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSS------------ 635
Query: 238 IAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPD 297
I+ +++ + + + + ++ + ++P+ + P Q + +QP R +P Q +
Sbjct: 636 ISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQ--PAQ-SLPSQPLLRSPLPLQQK--- 689
Query: 298 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 357
LL + ++ Q + +V +Q Q Q Q + +T P + T ++ Q
Sbjct: 690 LLLQQMQNQPIAGMGYQV----SQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ 745
Query: 358 QKQVQPQLQQEAEP-QKQVQPQVQPQAHSQGPRQVQLQQE-AEPLKQVQPQVQPQAH-SQ 414
Q + QL + + Q+Q+ Q Q Q+ LQQ+ +++ PQ Q H S+
Sbjct: 746 QSLLNQQLMGKKQTLQRQIMEQKQ---------QLLLQQQMLADAEKIAPQDQINRHLSR 796
Query: 415 PP 416
PP
Sbjct: 797 PP 798
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 73.6 bits (179), Expect = 8e-13
Identities = 62/199 (31%), Positives = 92/199 (46%), Gaps = 29/199 (14%)
Query: 282 QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
Q Q++++ Q LP A + V P QP+ Q AQ Q QTQP+ P+ QP+
Sbjct: 2364 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2418
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
+Q Q + QT + QP Q ++PQ V Q QPQ++ QG V++Q +
Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQ--VAAQSQPQSNVQGQSPVRVQSPS--- 2473
Query: 401 KQVQPQVQPQAHSQ--PPRQVQLQLQKQ----VQTQTYPQVHTQAQPSVQPQ-------- 446
Q +++P SQ P +Q Q+Q +Q T Q+ +Q QP QPQ
Sbjct: 2474 ---QTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAV 2530
Query: 447 -EHPPAQVSVQPPEQTHEQ 464
EH + S+ P E+ Q
Sbjct: 2531 IEHLKQKKSMTPAEREENQ 2549
Score = 61.6 bits (148), Expect = 3e-09
Identities = 65/225 (28%), Positives = 93/225 (41%), Gaps = 23/225 (10%)
Query: 275 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334
GQLQ+ Q + P Q L+ A+ + RF L A S T + +T
Sbjct: 2303 GQLQLIPQGVTVLPGPGQ----QLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTA 2358
Query: 335 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ-----EAEPQK-QVQPQVQPQAHSQGP 388
+Q Q++ SP+ V Q K + P EA+PQ Q Q QPQ Q P
Sbjct: 2359 AGTG----EQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSP 2414
Query: 389 RQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ-VQLQLQK-QVQTQTYPQVHTQAQPSVQPQ 446
Q ++Q + E VQ Q +H Q Q K QV Q+ PQ + Q Q V+ Q
Sbjct: 2415 AQPEVQTQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQ 2470
Query: 447 EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 491
P+Q ++P + P Q QV + P+ H L++P
Sbjct: 2471 S--PSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2512
Score = 61.2 bits (147), Expect = 4e-09
Identities = 68/242 (28%), Positives = 100/242 (41%), Gaps = 33/242 (13%)
Query: 153 QATRQSLLGPPPVGVPMNPSQFNLSGRNP----QKQARTSSSTTPNRKDSSSQTMPVEDK 208
Q T Q L P V V P Q + P Q+ T +TT +++ T+
Sbjct: 2300 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTT-A 2358
Query: 209 SDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEP 268
+ E + P+M +D+ LPP P EA A+ +
Sbjct: 2359 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG----------PAEAQPQTAQPSAQPQPQ 2408
Query: 269 TEKEPPGQLQVKAQPQARMTVPKQTQTPD----LLPEALEAQVLPRFQPRVLQVQAQ--- 321
T+ + P Q +V+ QP+ + + P ++ + QV + QP+ VQ Q
Sbjct: 2409 TQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQ-SNVQGQSPV 2467
Query: 322 -VQSQTQPRI-PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP--QLQQEAEPQKQVQP 377
VQS +Q RI PST +Q+ P Q Q QT TS Q +QP LQ ++ Q Q QP
Sbjct: 2468 RVQSPSQTRIRPSTPSQLSPGQQSQVQTTTS------QPIPIQPHTSLQIPSQGQPQSQP 2521
Query: 378 QV 379
QV
Sbjct: 2522 QV 2523
Score = 38.9 bits (89), Expect = 0.022
Identities = 135/693 (19%), Positives = 231/693 (33%), Gaps = 118/693 (17%)
Query: 164 PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
P+GVP P + PQ++ SS+ P R ++ QT PV ++ E E E R
Sbjct: 1970 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 2025
Query: 224 DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 282
+++ E AK++ ++ P S+ P +K +
Sbjct: 2026 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 2085
Query: 283 PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 332
+M + + +P + F V Q Q+ QVQ + IPS
Sbjct: 2086 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2145
Query: 333 --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 374
T T QP+ T+ V+ Q++P + P +Q
Sbjct: 2146 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2205
Query: 375 ----VQPQVQPQAHSQ------------GPRQVQLQQEAEPLKQVQPQVQPQAH-SQPPR 417
VQP Q +Q P V + L Q+ SQPPR
Sbjct: 2206 TPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPR 2265
Query: 418 QVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQ---VSVQPPEQTHEQPHTQPQVSLL 474
Q Q++ T AQ + Q H Q V +Q QT Q PQ +
Sbjct: 2266 PQQGQVKL-----------TMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTV 2314
Query: 475 APEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENR 534
P ++ A G +++ L P+ T + + G E R
Sbjct: 2315 LPGPGQQLM---------QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQR 2365
Query: 535 AREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQA---L 591
++ + QSS P T P + P + + P Q +
Sbjct: 2366 QSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEV 2425
Query: 592 QFFCYICKASCSSQQEFQDHMSEPQ---HQQRLGEIQHMSQACLLS-------------L 635
Q + S Q S+PQ Q +Q S + S L
Sbjct: 2426 QTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQL 2485
Query: 636 LPVPRDVLETEDEEPPPRRWCNTCQLYYMGD-------LIQHRRTQDHKIAKQSLRPF-- 686
P + ++T +P P + + Q+ G +++H +H K+S+ P
Sbjct: 2486 SPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAER 2545
Query: 687 -----CTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCFE 741
VCN+ K ++ + Q K + +E +S+E++ + Q+ + F+
Sbjct: 2546 EENQRMIVCNQVMKYILDKIDKEEKQAAKKRKRE-ESVEQKRSKQNATKLSAL----LFK 2600
Query: 742 GDEEEEEDD-------EDEEEIEVEEELCKQVR 767
E+ + + + +IEV+EEL + ++
Sbjct: 2601 HKEQLRAEILKKRALLDKDLQIEVQEELKRDLK 2633
Score = 31.6 bits (70), Expect = 3.5
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%)
Query: 709 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 761
+ D E + E+++ ++E+ +GD EE +D ED+EE E+EE+
Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 72.8 bits (177), Expect = 1e-12
Identities = 77/309 (24%), Positives = 120/309 (38%), Gaps = 30/309 (9%)
Query: 176 LSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP-PC 234
+ G + + +S S++ + +DS ++ P K P G E+ + Q P P
Sbjct: 695 MKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHP-GREQKKHHHHHHQQMQQAPAPV 753
Query: 235 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK--Q 292
P+ + P P P P + ++P PP + +A P + + P
Sbjct: 754 PQQPPPPPQQPPPPPPP-----------QQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIA 802
Query: 293 TQTPDLLPEALEAQVLP--RFQPRVLQVQAQVQSQTQPRIPST-DTQVQPKLQKQAQTQT 349
TQ P L P+ + P F +L + Q + P +P + P L + A
Sbjct: 803 TQVPVLEPQLPGSVFDPIGHFTQPILHLP---QPELPPHLPQPPEHSTPPHLNQHAVVSP 859
Query: 350 SPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQP 409
H L Q+ +P + A P K +P A +Q P Q A+P + + +P
Sbjct: 860 PALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPM-AQPPQVLLEDEEP 918
Query: 410 QAHSQPPRQVQLQLQK----QVQTQTYPQVHTQAQ--PSVQPQEHPPA--QVSVQPPEQT 461
A Q+QL LQ+ Q T P V Q+Q P + P HP Q+ QPP
Sbjct: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPP 978
Query: 462 HEQPHTQPQ 470
QP PQ
Sbjct: 979 PPQPQPPPQ 987
Score = 62.8 bits (151), Expect = 1e-09
Identities = 86/356 (24%), Positives = 119/356 (33%), Gaps = 38/356 (10%)
Query: 134 APSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTP 193
AP+ P Q P Q P +Q PPP P PS PQ+ A S+ P
Sbjct: 749 APAPVPQQPPPPPQQPPPPPPPQQQQQPPPP---PPPPSM-------PQQAAPAMKSSPP 798
Query: 194 NRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP------AP 247
+ + + + +P + P+ + P P+ E TP A
Sbjct: 799 PFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQP--PEHSTPPHLNQHAV 856
Query: 248 EPEPCEASELPAKRLRSSEEPTEKEP---------PGQLQVKAQPQARMTVPKQTQTPDL 298
P + LP + R S P P Q PQ M P Q D
Sbjct: 857 VSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDE 916
Query: 299 LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
P A L Q ++ Q Q P +PS Q QP S + + QQ
Sbjct: 917 EPPA---PPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQ 973
Query: 359 KQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ 418
P Q + PQ+Q QP +P H Q P Q + P Q Q P QPP
Sbjct: 974 PPPPPPPQPQPPPQQQHQPPPRP-VHLQ-PMQFSTHIQQPPPPQGQQPPHPPPGQQPPPP 1031
Query: 419 VQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQ------THEQPHTQ 468
+ Q+ +Q P+ H S P+ + + P+ TH+ P Q
Sbjct: 1032 QPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQ 1087
Score = 58.9 bits (141), Expect = 2e-08
Identities = 114/473 (24%), Positives = 162/473 (34%), Gaps = 112/473 (23%)
Query: 26 QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQ-----PLLNLQGTNSASLL 80
+Q++ Q+QQ P Q P P PP Q QQ P +A +
Sbjct: 734 EQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAM 793
Query: 81 NGSMLQRALLLQQLQGLDQFAMPPATYDTAG-LTMPTATLGNLRGYGMASPGLAAPSLTP 139
S + Q+ L+ +P + +D G T P L P L P
Sbjct: 794 KSS--PPPFIATQVPVLEP-QLPGSVFDPIGHFTQPILHL--------PQPELPPHLPQP 842
Query: 140 PQLATPNLQQFFPQATRQSLLGPPPV--GVPMNPSQ-FNLSGRNPQKQARTSSSTTPNRK 196
P+ +TP P + +++ PP + +P PS+ N + P K AR P
Sbjct: 843 PEHSTP------PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPAR-----PPAVS 891
Query: 197 DSSSQT--MPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEA 254
+ +QT +P + PP+ E EP PAP P
Sbjct: 892 PALTQTPLLPQPPMAQPPQVLLEDEEP-----------------------PAP-PLTSMQ 927
Query: 255 SELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPR 314
+L ++L+ + PT P +V Q+Q P LP P
Sbjct: 928 MQLYLQQLQKVQPPTPLLP--------------SVKVQSQPPPPLP-----------PPP 962
Query: 315 VLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ 374
VQ Q+Q Q P P Q QP Q+Q Q P H LQ Q +QQ PQ Q
Sbjct: 963 HPSVQQQLQQQPPPPPP---PQPQPPPQQQHQPPPRPVH--LQPMQFSTHIQQPPPPQGQ 1017
Query: 375 VQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQ 434
P P P Q A+P + +Q P+ H P Y
Sbjct: 1018 QPPHPPPGQQPPPP------QPAKPQQVIQHHHSPRHHKSDP---------------YST 1056
Query: 435 VHTQAQPSV----QPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVV 483
H + PS PQ ++ Q P Q + QP Q + + P+VV
Sbjct: 1057 GHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVV 1109
Score = 50.4 bits (119), Expect = 7e-06
Identities = 98/439 (22%), Positives = 142/439 (32%), Gaps = 63/439 (14%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
QQ Q++Q L ++ Q L +QQ LQQ PP P P PPQQ
Sbjct: 933 QQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQP---PPQQQ 989
Query: 65 QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRG 124
QP R + LQ +Q PP P G
Sbjct: 990 HQP-----------------PPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPP-------G 1025
Query: 125 YGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGV-PMNPSQFNLSGRNPQK 183
P A P +P + P +T P P+ + SQF
Sbjct: 1026 QQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPP 1085
Query: 184 QARTSSSTTPNRKDSSSQTMPV----EDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239
Q R S Q P+ E+K P E P + PE P PE I
Sbjct: 1086 QQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSL-RPEP---PKHPESIK 1141
Query: 240 KEKRTP-APEPEPCEASE--------------LPAKRLRSSEEPTEKEPPGQLQVKAQPQ 284
P PE +P + P K + E T P L++K
Sbjct: 1142 APVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGS 1201
Query: 285 ARMTVPKQTQTP--------DLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQ 336
V K TP D + A + + L+ QA+ + + R+ +
Sbjct: 1202 WASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMR 1261
Query: 337 VQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ----VQPQVQPQAHSQGPRQVQ 392
+ Q + + E +Q+Q Q Q Q++ + Q+Q V PQA S P+ +
Sbjct: 1262 SREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSML 1321
Query: 393 LQQEAEPLKQVQPQVQPQA 411
QQ K+ Q + + +A
Sbjct: 1322 DQQRELARKREQERRRREA 1340
Score = 35.4 bits (80), Expect = 0.24
Identities = 43/178 (24%), Positives = 62/178 (34%), Gaps = 16/178 (8%)
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
LQK + T +++ Q + + + ++E K V + P Q Q Q P
Sbjct: 158 LQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPP 217
Query: 401 KQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQ 460
Q P H P L +Q V T PQ Q P V PQ PP + QP +
Sbjct: 218 VQATP------HPFPAVTPDLIVQTPVMTVVPPQP-LQTPPPVPPQPQPPPAPAPQPVQS 270
Query: 461 -------THEQPHTQPQVSLLAPEQTPVVVHVC--GLEMPPDAVEAGGGMEKTLPEPV 509
T + T+ V A TP + +PP+ G + PV
Sbjct: 271 HPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPV 328
Score = 33.1 bits (74), Expect = 1.2
Identities = 18/41 (43%), Positives = 23/41 (56%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ 44
Q+QQQQ +Q+QQQ QQ Q + Q Q Q Q +L Q
Sbjct: 1283 QEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQ 1323
Score = 30.8 bits (68), Expect = 5.9
Identities = 40/179 (22%), Positives = 66/179 (36%), Gaps = 21/179 (11%)
Query: 178 GRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSE-----EAAEPRM--DTPEDQD 230
GR A+ ST PN +S+ + +PP A P + TP
Sbjct: 182 GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTV 241
Query: 231 LPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP 290
+PP P +TP P P + PA + S P P ++ K + +
Sbjct: 242 VPPQP------LQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK---- 291
Query: 291 KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS---TDTQVQPKLQKQAQ 346
T TP + E LP +P+ ++ + +S + P D+Q P +K ++
Sbjct: 292 ADTTTPTTIDPIHEPPSLPP-EPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSK 349
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 72.0 bits (175), Expect = 2e-12
Identities = 79/359 (22%), Positives = 150/359 (41%), Gaps = 43/359 (11%)
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
P+K P K + V + PE P+ + P +P P+
Sbjct: 9954 PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP-PGQLQVKAQPQARMTVPKQTQTPDLL 299
E++ P P P+ EA + P +K P P +V+A P VPK+ L+
Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKK-----LI 10068
Query: 300 PEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA-QTQTSPEHLVL-Q 357
PE + +P+ +V+A + R P P+ ++ + + PE VL +
Sbjct: 10069 PEEKKPTPVPK------KVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPE 10122
Query: 358 QKQVQPQLQQEAEPQKQVQP---QVQPQAHSQGPRQVQLQQEAE--PLKQVQPQVQPQAH 412
+++V P+ ++ +++V P ++ P+ P + + +E E P ++V P+V+P+
Sbjct: 10123 EEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVP 10182
Query: 413 SQPP----------RQVQLQLQKQVQTQTYPQVHTQAQPS--VQPQEHP--PAQVSVQP- 457
P ++V + +++ P+V + + + P+E P +V+ +P
Sbjct: 10183 VPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPE 10242
Query: 458 -----PEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP---PDAVEA-GGGMEKTLPE 507
E+ E+P + +V +AP + P V+ E P P VEA + K +PE
Sbjct: 10243 EEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPE 10301
Score = 66.6 bits (161), Expect = 1e-10
Identities = 85/390 (21%), Positives = 142/390 (36%), Gaps = 65/390 (16%)
Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR---------- 179
P P + PP+ P + P A + PP VP P + +
Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKPEA---PPPKVPEAPKEVVPEKKVPVPPPKKPE 10547
Query: 180 -NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEE-----------AAEPRMDTPE 227
P K + P +K + +P + +S PPE E AA P+
Sbjct: 10548 VPPTKVPEVPKAAVPEKK--VPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVT 10605
Query: 228 DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 287
+P P+++ EK+ P P P+ E + P +K P
Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPE------------- 10652
Query: 288 TVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQT 347
+P + ++P PE E + +V + + P++ + P+ + A
Sbjct: 10653 AIPPKPESPP--PEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVV 10710
Query: 348 QTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQV-QLQQEAEPLKQVQPQ 406
PE L +V P++ +E P+K+V P V P+ P +V ++ +E P K+V
Sbjct: 10711 AKKPE---LPPVKV-PEVPKEVVPEKKV-PLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765
Query: 407 VQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 466
+P+ PP +V P+V + +P P + PPE E
Sbjct: 10766 KKPEV---PPAKV-------------PEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEE 10809
Query: 467 TQPQVSLLAPEQTPV-VVHVCGLEMPPDAV 495
P+ + E+ PV V E+PP AV
Sbjct: 10810 IAPEEEIAPEEEKPVPVAEEEEPEVPPPAV 10839
Score = 60.1 bits (144), Expect = 9e-09
Identities = 66/266 (24%), Positives = 110/266 (41%), Gaps = 27/266 (10%)
Query: 246 APEPEPCEASELPAKRLRSSEEPTE-KEPPGQLQVKAQPQARMT-VPKQTQTPDLLPEAL 303
A E E E + P K SE+ K+PP ++ + +P A++ VPK+ + +
Sbjct: 10427 AEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPE 10486
Query: 304 EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV----LQQK 359
E +V P P VL + V + P P+ + P +A + PE V ++
Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKP 10546
Query: 360 QVQ----PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQV------QPQVQP 409
+V P++ + A P+K+V + P+ S P + +E P K+V +P+V P
Sbjct: 10547 EVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTP 10606
Query: 410 QAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQP 469
+ P++V + + V P+V P V P +V PE +P + P
Sbjct: 10607 VKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKV----PEAIPPKPESPP 10662
Query: 470 QVSLLAPEQTPVVVHVCGLEMPPDAV 495
PE+ LE PP V
Sbjct: 10663 PEVFEEPEEV-------ALEEPPAEV 10681
Score = 59.3 bits (142), Expect = 2e-08
Identities = 71/360 (19%), Positives = 138/360 (38%), Gaps = 62/360 (17%)
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
P+K P ++ +P K PE P+ +P P+
Sbjct: 9982 PKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVP 10041
Query: 241 EKRTPAPEPE-----PCEASELPAKRLRSSEEPTE-----KEPPGQLQVKAQPQA----- 285
EK+ P P P+ P + E+P K + ++PT + PP ++ K +P
Sbjct: 10042 EKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVAL 10101
Query: 286 ---------RMTVPKQTQTPD---LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPST 333
VP++ P+ +LPE E +VLP + VL + ++ + + P
Sbjct: 10102 PQEEEVLFEEEIVPEEEVLPEEEEVLPE--EEEVLPE-EEEVLPEEEEIPPEEEEVPPEE 10158
Query: 334 D---------------TQVQPKLQKQA-----QTQTSPEHLVLQQKQVQPQLQQEAEPQK 373
+ +V+PK+ A + + + + +V+ +K+ P + P+K
Sbjct: 10159 EYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKK 10218
Query: 374 QVQPQV-QPQAHSQGPRQVQLQQEAEPLKQVQ-----PQVQPQAHSQPPRQVQLQLQKQV 427
+ ++ P+ P +V + E EP+ + + P ++ PPR ++ +
Sbjct: 10219 VEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVP 10278
Query: 428 QTQTYPQVHTQAQPSVQPQEHP------PAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 481
+ T +A P+ ++ P P Q PP + E P P+ +L P++ V
Sbjct: 10279 EAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAV 10338
Score = 53.1 bits (126), Expect = 1e-06
Identities = 86/411 (20%), Positives = 161/411 (39%), Gaps = 52/411 (12%)
Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGP-----PPVGVPMNPSQFNLSGRNPQK 183
+P + A P + P + + + L+ P PP VP P + P+K
Sbjct: 10706 APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV-----PEK 10760
Query: 184 Q-ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 242
+ A P K PV ++ E A P + E+ + E+IA E+
Sbjct: 10761 KVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEE 10820
Query: 243 RTPAP-----EPE--PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQT 295
P P EPE P E P K + + P K+P + +P+ + PK
Sbjct: 10821 EKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPR 10880
Query: 296 PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV 355
P P A + + + ++ Q++A IP +V K Q + + +P +
Sbjct: 10881 PPPPPPAPPKEDV---KEKIFQLKA---------IPK--KKVPEKPQVPEKVELTPLKVP 10926
Query: 356 LQQKQVQPQL-QQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQ 414
+K+V+ L +++ EP+++V V + P + + + E + L++V+ P+
Sbjct: 10927 GGEKKVRKLLPERKPEPKEEV---VLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPE--PP 10981
Query: 415 PPRQVQ-------LQLQKQVQTQT-YPQVHTQAQ-PSVQPQEHPPAQVSVQPPEQTHEQP 465
PP+ V+ + ++++ T P++ P+ +P+ P A+V P +P
Sbjct: 10982 PPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEP 11041
Query: 466 HTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSME 516
+ AP PVV + P + G K +P+ + + E
Sbjct: 11042 -----TPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAE 11087
Score = 46.2 bits (108), Expect = 1e-04
Identities = 72/355 (20%), Positives = 142/355 (40%), Gaps = 46/355 (12%)
Query: 203 MPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE----PCEASELP 258
+P+ K +PP + P+ PE++ P P+ KE P PE P ++P
Sbjct: 9303 VPIPKKVEPP-APKVPEVPKKPVPEEKKPVPVPK---KEPAAPPKVPEVPKKPVPEEKIP 9358
Query: 259 AKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV------LPRFQ 312
+ E P K P Q V + + + ++ P +PE + +V +PR +
Sbjct: 9359 VPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKE 9418
Query: 313 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA---QTQTSPEHLVLQQKQVQPQLQQEA 369
V +V + + +P V + K+A + + S + +V +++ V + A
Sbjct: 9419 EEV-PPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFA 9477
Query: 370 EPQKQVQPQVQPQAHSQGPR-------QVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ 422
PQ+ + + A + + + +E E ++ + +V + P + ++
Sbjct: 9478 VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVE 9537
Query: 423 -----LQKQVQTQTYPQVHTQAQPSV-------QPQEHPPAQVSVQPPEQTHEQ--PHTQ 468
+ K+V+ + Q + V + +E PPA+V P + E+ P
Sbjct: 9538 EKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPV 9597
Query: 469 PQVSLLAPEQTPVVVH--VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNE 521
P+ + P + P V ++PP ++ ME+ LP V T+ M+ Q E
Sbjct: 9598 PKKEKVPPPKVPEEPKKPVPEKKVPPKVIK----MEEPLPAKV-TERHMQITQEE 9647
Score = 41.6 bits (96), Expect = 0.003
Identities = 78/369 (21%), Positives = 147/369 (39%), Gaps = 61/369 (16%)
Query: 203 MPVEDKSDPPEGSEEAAEP----RMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELP 258
+PV+ + P ++ A P + PE++ P P+ K P P P E ++
Sbjct: 9793 IPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPK-----KLKPPPPKVPEEPKKVF 9847
Query: 259 AKRLRSSEEPTEKE----PPGQLQVKAQ---PQARMTVPKQTQTP---------DLLPE- 301
+++R S EKE P ++ +K + + ++ VP++ P +L PE
Sbjct: 9848 EEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEE 9907
Query: 302 -ALEAQVLPRFQPRVLQVQAQ---------VQSQTQPRIPSTDTQVQPK----------- 340
A E +V+ + +++ + + + + P IP +V K
Sbjct: 9908 VAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPV 9967
Query: 341 -LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQV--QPQAHSQGPRQVQLQQEA 397
+K+A PE +++V + ++ +P P+V +P + P V + EA
Sbjct: 9968 PKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEA 10027
Query: 398 EPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQT--YPQVHTQAQPSVQPQEHPPAQVSV 455
P K + +P P ++V + K+V+ P+V + P + P +V
Sbjct: 10028 PPAKVPEVPKKPV----PEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEA 10083
Query: 456 QPPEQTHEQPHTQPQVSLLAPEQTPVVVH---VCGLEMPPDAVEAGGGMEKTLPEPVGTQ 512
PP+ ++ V+L P++ V+ V E+ P+ E E+ LPE
Sbjct: 10084 PPPKVPKKREPVPVPVAL--PQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVL 10141
Query: 513 VSMEEIQNE 521
EEI E
Sbjct: 10142 PEEEEIPPE 10150
Score = 38.9 bits (89), Expect = 0.022
Identities = 119/608 (19%), Positives = 227/608 (37%), Gaps = 86/608 (14%)
Query: 192 TPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDL--PPCPEDIAKEKRTPAPEP 249
TP K + + V K+ + + A+P+ TP ++ + PP P + PA P
Sbjct: 8971 TPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTL-----IPAKAP 9025
Query: 250 E----PCEASELPAKRL-RSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALE 304
E +A E+ + R E EKE + + + R+ + + D E
Sbjct: 9026 EIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYD------E 9079
Query: 305 AQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ---KQAQTQTSPEHLVLQQKQV 361
+V P +P + + +V + + ++ Q E + ++
Sbjct: 9080 LEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEE 9139
Query: 362 QPQLQQEAEPQKQVQPQVQPQAHSQG-PRQVQLQQEAEPLKQVQ----PQVQPQAHSQPP 416
+ QE E QVQ +V ++H + P +V ++ P K ++ +++ +
Sbjct: 9140 WEEAYQERE-VIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEE 9198
Query: 417 RQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQ---------PPEQTHEQPHT 467
+VQ+ +V + PQ +PS P + +V V E+ HT
Sbjct: 9199 EKVQVTKVPEVSKKIVPQ-----KPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHT 9253
Query: 468 QPQVSLLAPE-QTPVV----VHVC---GLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQ 519
+ +VS+ PE Q +V +HV +E PP E EK PE V ++++
Sbjct: 9254 EEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPEL---PEKPAPEEVAPVPIPKKVE 9310
Query: 520 NESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSST 579
+ +V + + P + V + + VP PVP V
Sbjct: 9311 PPAPKVPEVPKKPVPEEKKP--------VPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVA 9362
Query: 580 PAATSTPSK--QALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLP 637
+ P+K + + K + +Q+E + P+ ++ + P
Sbjct: 9363 KKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERK---------P 9413
Query: 638 VPRDVLETEDEEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTP 697
VPR E+E PPP + + + + +AK++ P V +
Sbjct: 9414 VPR----KEEEVPPPPK----VPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEE 9465
Query: 698 RKFVEHVKSQGHKDKAKELK----SLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 753
++FV K + E+ S E+E + +E+ +++ + +E EEE++ +
Sbjct: 9466 KRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISV---YREEEREEEEEAEV 9522
Query: 754 EEIEVEEE 761
E EV EE
Sbjct: 9523 TEYEVMEE 9530
Score = 38.1 bits (87), Expect = 0.037
Identities = 61/316 (19%), Positives = 117/316 (37%), Gaps = 54/316 (17%)
Query: 137 LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP---QKQARTSSSTTP 193
+ P + P ++ P A + PPP VP P + + P + +A P
Sbjct: 10810 IAPEEEIAPEEEKPVPVAEEEEPEVPPPA-VPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868
Query: 194 NRKDSSSQTMPVEDKSDPPEGSEEAAE--------PRMDTPEDQDLPPCPE--------- 236
+ + P P E+ E P+ PE +P E
Sbjct: 10869 EKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGG 10928
Query: 237 DIAKEKRTPAPEPEPCEASELPA---------------KRLRSSEEPTEKEPPG-----Q 276
+ K P +PEP E L + K+L ++P EPP +
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEE 10988
Query: 277 LQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQ 336
++V + +P+ T+ P++ P A LP +P+ + +A+V++ P + T
Sbjct: 10989 VEVPTVTKRERKIPEPTKVPEIKP----AIPLPAPEPKP-KPEAEVKTIKPPPVEPEPTP 11043
Query: 337 VQ-----PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGP--- 388
+ P + K+A+ + E + ++ ++ P + + +++P + + P
Sbjct: 11044 IAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDE 11103
Query: 389 RQVQLQQEAEPLKQVQ 404
Q +A PLK V+
Sbjct: 11104 APFTYQLKAVPLKFVK 11119
Score = 31.6 bits (70), Expect = 3.5
Identities = 60/320 (18%), Positives = 118/320 (36%), Gaps = 45/320 (14%)
Query: 196 KDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEAS 255
K + ++ + DK+ E E + T + + + E I KE A+
Sbjct: 473 KTAVTKVVVAADKAKEQELKSRTKE--VITTKQEQMHVTHEQIRKETEKTFVPKVVISAA 530
Query: 256 ELPAKRLRSSEEPTEKEPP-------GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL 308
+ + R SEE T+K+ + ++ A + K T+ + +P A E
Sbjct: 531 KAKEQETRISEEITKKQKQVTQEAIRQETEITAASMVVVATAKSTKL-ETVPGAQEETTT 589
Query: 309 PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ---PQL 365
+ Q + ++ +T+ + PK+++Q E + +++QVQ ++
Sbjct: 590 QQDQMHLSY--EKIMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKREQVQITQEKM 647
Query: 366 QQEAEP-----------QKQVQPQVQPQAHSQGPRQVQLQ---------QEAEPLKQVQP 405
++EAE + + Q + + RQ Q+Q ++AE + V
Sbjct: 648 RKEAEKTALSTIAVATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKKAEAVATVVA 707
Query: 406 QVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQP 465
V QA + PR+ + Q T + +E A +PP++ +P
Sbjct: 708 AVD-QARVREPREPGHLEESYAQQTTLEYGY---------KERISAAKVAEPPQRPASEP 757
Query: 466 HTQPQVSLLAPEQTPVVVHV 485
H P+ Q P H+
Sbjct: 758 HVVPKAVKPRVIQAPSETHI 777
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 71.6 bits (174), Expect = 3e-12
Identities = 109/464 (23%), Positives = 172/464 (37%), Gaps = 56/464 (12%)
Query: 13 QQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQ 72
++Q L QLQQ Q Q Q Q Q +LQ L PP P P+ G QP P +
Sbjct: 54 REQHLAQLQQLQ-QMHQKQMQCVLQPHHL--PPPPLPPPPVMPGGGYGDWQPPPPPMPPP 110
Query: 73 GTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGL 132
+ S + +L Q G PP L + SP
Sbjct: 111 PGPALSYQKQQQYKHQMLHHQRDG------PPG----------------LVPMELESPPE 148
Query: 133 AAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTT 192
+ P PP P Q + P PP P P ++P Q+ + + +
Sbjct: 149 SPP--VPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPS 206
Query: 193 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 252
+ SSSQ+ +S P + P + Q L P P +T + EP
Sbjct: 207 YSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTV-QQEPL 265
Query: 253 EASELPAKRLRSSEEPTEKEP-PGQLQVKAQPQ---ARMTVPKQTQTPDLLPEALEAQVL 308
E+ AK + ++ EP P + + Q Q + + Q +T LP + V+
Sbjct: 266 ESG---AKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVV 322
Query: 309 PRFQPRVLQVQAQVQSQTQ-PRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 367
+ P ++ + V + +Q P PS++ P ++ PE + + +L+Q
Sbjct: 323 AKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQ 382
Query: 368 ----EAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQL 423
A Q+ Q +V Q + QLQQ L+Q Q +QP H Q V +QL
Sbjct: 383 LQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQ---ILQQYQQIIQPPPHIQ-TMSVDMQL 438
Query: 424 QK-QVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 466
+ ++Q Q + ++ + + Q E EQ H PH
Sbjct: 439 RHYEMQQQQFQHLYQEWEREFQLWE-----------EQLHSYPH 471
Score = 41.6 bits (96), Expect = 0.003
Identities = 77/312 (24%), Positives = 104/312 (33%), Gaps = 58/312 (18%)
Query: 11 QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS---RGLPPQQPQQP 67
QQ QQ Q Q + Q+ Q QQ+LQ Q + Q PP M+V R QQ Q
Sbjct: 391 QQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQ-TMSVDMQLRHYEMQQQQFQ 449
Query: 68 LLNLQGTNSASL-----------------------LNGSMLQRALLLQQL---------Q 95
L + L G M LQ+ Q
Sbjct: 450 HLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQ 509
Query: 96 GLDQFAMPPATYDTAGL-----TMPTATLGNLRGYGMASPGLAA---PSLTPPQLATPNL 147
+ +MPP + + TMP L + P L A P PP + P+L
Sbjct: 510 YMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSL 569
Query: 148 QQFFP---QATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 204
P S GPPPV + P + +G P + SST P +P
Sbjct: 570 PTSVPPPGMPPSLSSAGPPPV---LPPPSLSSAGPPPVLPPPSLSSTAP----PPVMPLP 622
Query: 205 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
+ PP G P+ P+ P P ++ + P +P P + LP
Sbjct: 623 PLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVP-EKPRP---ALLPTPVSFG 678
Query: 265 SEEPTEKEPPGQ 276
S PT PP Q
Sbjct: 679 SAPPTTYHPPLQ 690
Score = 33.5 bits (75), Expect = 0.91
Identities = 102/498 (20%), Positives = 173/498 (34%), Gaps = 64/498 (12%)
Query: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ--SPPQAPLPMAVSRG 58
+ S + QLQ+ ++Q + Q Q Q+++ Q + Q P P
Sbjct: 466 LHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQ 525
Query: 59 LPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTAT 118
+PP P P L + ++ ++ G+ MPP+ +PT+
Sbjct: 526 MPPPLPTMPPPVLPPSLPPPVMPPALPATV----PPPGMPPPVMPPS--------LPTSV 573
Query: 119 LGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSG 178
++S G P L PP L++ P + S PP + +P S G
Sbjct: 574 PPPGMPPSLSSAG-PPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPG 632
Query: 179 RNP---QKQARTSSSTTPNRKDSSSQTMPVEDKSD----PPEGSEEAAEPRMDTPEDQDL 231
P + + P SSSQ+ V +K P S +A P P Q
Sbjct: 633 IPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSA 692
Query: 232 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 291
P + +K P S LP S + G + A P +T K
Sbjct: 693 GPSEQVNSK---------APLSKSALPYSSFSSDQ--------GLGESSAAPSQPITAVK 735
Query: 292 Q--TQTPDLLPEA-----LEAQVLPRFQ-PRVLQVQAQVQSQTQPRIPSTDTQ----VQP 339
++ LLP+ LE+ PRF PR + +P+ P + +P
Sbjct: 736 DMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRP 795
Query: 340 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQ-EAE 398
+ + T + ++ + P Q P + P+ Q +GP+ QQ + +
Sbjct: 796 RYEGHPAEGTKSKWGMIPR---GPASQFYITPSTSLSPR-QSGPQWKGPKPAFGQQHQQQ 851
Query: 399 PLKQVQP---QVQPQAHSQPPRQVQLQLQK-----QVQTQTYPQVHTQAQPSVQPQEHPP 450
P Q +P +P A + +Q ++Q + + S QE P
Sbjct: 852 PKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPK 911
Query: 451 AQVSVQPPEQTHEQPHTQ 468
++VS P E ++ + Q
Sbjct: 912 SEVSEGPVEPSNWDQNVQ 929
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 71.2 bits (173), Expect = 4e-12
Identities = 111/485 (22%), Positives = 167/485 (34%), Gaps = 70/485 (14%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
+Q+ + QQ Q +LQQ Q + + +Q+ ++ QQ L P P + PQ P
Sbjct: 1810 KQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTP 1869
Query: 65 QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRG 124
Q Q Q +MPP L +
Sbjct: 1870 QP------------------------TSQPQPTPPNSMPP-------------YLPRTQA 1892
Query: 125 YGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQ 184
G S G AA +TPP TP PQ + L GPPP V M Q + ++
Sbjct: 1893 AGPVSQGKAAGQVTPP---TP------PQTAQPPLPGPPPAAVEM-AMQIQRAAETQRQM 1942
Query: 185 ARTSSSTTPNRKDSSSQTMPVEDKSDPP---EGSEEAAEPRMDTPEDQDLPPCPE-DIAK 240
A P + T +PP G EP M Q PP + + +
Sbjct: 1943 AHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQ 2002
Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP-PGQLQVKAQPQARMTVPKQTQTPDLL 299
++ + P P S + +P P PG QV P TV +Q L
Sbjct: 2003 PQQLQSGMPRPAMMS------VAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQAL--QNL 2054
Query: 300 PEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQK 359
L + P Q +VL + P++ + ++ + K A + P
Sbjct: 2055 LRTLRSPSSPLQQQQVLSI-----LHANPQLLA--AFIKQRAAKYANSNPQPIPGQPGMP 2107
Query: 360 QVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQV 419
Q QP LQ P +Q P + P Q +Q+ P +Q Q Q+QP P+
Sbjct: 2108 QGQPGLQPPTMPGQQ-GVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQ 2166
Query: 420 QLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 479
Q+ + + + + Q +Q Q+ A + P H Q QPQ P+Q
Sbjct: 2167 QMNMNHNTMPSQFRDI-LRRQQMMQQQQQQGAGPGIGPGMANHNQ-FQQPQGVGYPPQQQ 2224
Query: 480 PVVVH 484
+ H
Sbjct: 2225 QRMQH 2229
Score = 58.9 bits (141), Expect = 2e-08
Identities = 94/435 (21%), Positives = 165/435 (37%), Gaps = 61/435 (14%)
Query: 27 QQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQ 86
Q++L++++ +LQ+ +P++++ G QPQ + + S++ GS+
Sbjct: 641 QKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPN 700
Query: 87 RAL-LLQQLQGLDQF-----AMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPP 140
+ + + GL+QF A PP T P G L G +P P P
Sbjct: 701 QMMPRITPQSGLNQFGQMSMAQPPIV---PRQTPPLQHHGQLAQPGALNP----PMGYGP 753
Query: 141 QLATPNLQ-QFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTP------ 193
++ P+ Q QF PQ T+ G +P+ PS SG+ P QA+ SSS+ P
Sbjct: 754 RMQQPSNQGQFLPQ-TQFPSQGMNVTNIPLAPS----SGQAPVSQAQMSSSSCPVNSPIM 808
Query: 194 ---------------------NRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP 232
N P + P G+++ + P
Sbjct: 809 PPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPV----- 863
Query: 233 PCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQ 292
P P + ++ A P P + P +L +P+ P Q + QP+++ +
Sbjct: 864 PTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAAS 923
Query: 293 TQTP--DLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS 350
TP LLP P QP V ++ QV + P ST+ Q +KQ +
Sbjct: 924 VPTPTAPLLP---PQPATPLSQPAV-SIEGQVSN--PPSTSSTEVNSQAIAEKQPSQEVK 977
Query: 351 PEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQ 410
E ++ Q +P Q + + + ++ R +L+ E + ++ QP
Sbjct: 978 ME-AKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKE-EEDQPSTSAT 1035
Query: 411 AHSQPPRQVQLQLQK 425
S P Q + ++ K
Sbjct: 1036 QSSPAPGQSKKKIFK 1050
Score = 52.8 bits (125), Expect = 1e-06
Identities = 78/319 (24%), Positives = 103/319 (32%), Gaps = 40/319 (12%)
Query: 268 PTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQ 327
P ++P Q Q Q Q P Q +P A + P Q ++ V S
Sbjct: 753 PRMQQPSNQGQFLPQTQ----FPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIM 808
Query: 328 PRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQK---QVQPQLQQEAEPQKQVQ-------- 376
P P+L + A Q SP + + P + + P +
Sbjct: 809 PPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPA 868
Query: 377 --PQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQ 434
P Q QA PRQ P Q+ QVQP + P Q Q Q + Q T
Sbjct: 869 MPPGPQSQALHPPPRQT----PTPPTTQLPQQVQPSLPAAPSAD-QPQQQPRSQQSTAAS 923
Query: 435 VHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA 494
V T P + PQ PA QP Q P S T V + P
Sbjct: 924 VPTPTAPLLPPQ---PATPLSQPAVSIEGQVSNPPSTS-----STEVNSQAIAEKQPSQE 975
Query: 495 VEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQ 554
V+ ME PEP TQ C ++ E E R+ E LK I +
Sbjct: 976 VKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTE----------LKTEIKE 1025
Query: 555 SSDSRAFSTVPLTPVPRPS 573
D + S +P P S
Sbjct: 1026 EEDQPSTSATQSSPAPGQS 1044
Score = 39.7 bits (91), Expect = 0.013
Identities = 52/217 (23%), Positives = 78/217 (35%), Gaps = 44/217 (20%)
Query: 2 FSQQQQQQLQQQQQQLQQLQQQQLQQ------------QQLQQQQLLQLQQLLQQSPPQA 49
+ QQQQ++Q QQ+QQ Q+ Q Q QQ+LLQ Q P
Sbjct: 2219 YPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQ----QQMGSPVQ 2274
Query: 50 PLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT 109
P PM+ + + P Q Q P +LQG + L+ +Q P
Sbjct: 2275 PNPMSPQQHMLPNQAQSP--HLQGQQIPNSLS----------------NQVRSPQPVPSP 2316
Query: 110 AGLTMPTATLGNLRGYGMASPGLAAPSLTPPQ------LATPNLQQFFPQATRQSLLGPP 163
+ P + + R SP +P + P A P Q F + S+L
Sbjct: 2317 RPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQ- 2375
Query: 164 PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSS 200
+ NP NL G + ++ ++ N S S
Sbjct: 2376 ---LASNPGMANLHGASATDLGLSTDNSDLNSNLSQS 2409
Score = 33.1 bits (74), Expect = 1.2
Identities = 54/228 (23%), Positives = 84/228 (36%), Gaps = 40/228 (17%)
Query: 4 QQQQQQLQQ-------QQQQLQ--------QLQQQQLQQQQLQQQQLLQLQQLL---QQS 45
QQ QQQLQ Q QQ+ Q + +QQ +QQQQ + +
Sbjct: 2148 QQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMAN 2207
Query: 46 PPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPA 105
Q P V G PPQQ Q+ ++Q ++ L +AL + L +
Sbjct: 2208 HNQFQQPQGV--GYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLL 2265
Query: 106 TYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQ-QFFPQATRQSLLGPPP 164
P +P + P Q +P+LQ Q P + + P P
Sbjct: 2266 QQQMGSPVQP-------------NPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQP 2312
Query: 165 VGVPMNPSQFNLSGRNPQKQARTS------SSTTPNRKDSSSQTMPVE 206
V P SQ S +P+ Q + S +++P+ ++Q P+E
Sbjct: 2313 VPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPME 2360
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 71.2 bits (173), Expect = 4e-12
Identities = 77/376 (20%), Positives = 149/376 (39%), Gaps = 36/376 (9%)
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
P+ + + +++ QT P + + E EEA PE +D+ ++
Sbjct: 1933 PESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQ------PESEDVEALEVEVET 1986
Query: 241 EKRT--PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTP-- 296
++ PE E EA E + + EE + + Q K++ + V +TQ
Sbjct: 1987 QEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEG 2046
Query: 297 DLLPEALEAQVLPRFQPRVLQVQAQVQS---QTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
D PE+ + P + + + +VQ + P D Q +A+ + PE
Sbjct: 2047 DAQPES-DGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQ-------EAEGEAQPES 2098
Query: 354 LVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEP------LKQVQPQV 407
++ + + + Q+ AE + + + + Q S+G + + EA+P + + +
Sbjct: 2099 EGVEAPEAEGEAQK-AEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEA 2157
Query: 408 QPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHT 467
QP++ ++ + + Q +++ P+ +AQP + E P A+ QP + E P
Sbjct: 2158 QPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEA 2217
Query: 468 QPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLD 527
+ + PE V E P++ G +K P QVS+ + Q+E A
Sbjct: 2218 EEEAQ---PEPEGVETPEAEGEAQPESEGETQGEKKGSP-----QVSLGDGQSEEASESS 2269
Query: 528 VGECENRAREMPGVWG 543
E+R P G
Sbjct: 2270 SPVPEDRPTPPPSPGG 2285
Score = 65.1 bits (157), Expect = 3e-10
Identities = 70/331 (21%), Positives = 129/331 (38%), Gaps = 34/331 (10%)
Query: 208 KSDPPEGSE--EAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSS 265
+SD EG E EA E + P D + + PE E EA E + S
Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPES 1887
Query: 266 EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 325
E+ E ++Q +++ K+ Q EALE + +
Sbjct: 1888 EDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETE-----------------GE 1930
Query: 326 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHS 385
+P + Q + ++A+ QT PE V++ ++ + + Q E+E + ++ +V+ Q +
Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQ-EA 1989
Query: 386 QGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQP 445
+G Q + + P + + ++Q P ++ Q + + + +V + Q +
Sbjct: 1990 EGEAQPESEDVEAP--EAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKT--E 2045
Query: 446 QEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTL 505
+ P V+ PE E + +V E P V DA EA G +
Sbjct: 2046 GDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV-------DAQEAEG---EAQ 2095
Query: 506 PEPVGTQVSMEEIQNESACGLDVGECENRAR 536
PE G + E + + A G++ E E A+
Sbjct: 2096 PESEGVEAPEAEGEAQKAEGIEAPETEGEAQ 2126
Score = 55.8 bits (133), Expect = 2e-07
Identities = 60/265 (22%), Positives = 111/265 (41%), Gaps = 28/265 (10%)
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCPEDI- 238
P+ + + + + P D + PE EEA E + E + + P ED+
Sbjct: 2027 PKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVD 2086
Query: 239 AKEKRTPA-PEPEPCEASELP-----AKRLRSSEEPTEKEPPGQ------LQVKAQPQAR 286
A+E A PE E EA E A+ + + E E +P + + +AQP++
Sbjct: 2087 AQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE 2146
Query: 287 MTVPKQTQTPDLLPEA--LEAQVLPR-FQPRVLQVQA-QVQSQTQPR-----IPSTDTQV 337
V Q + PE+ +EAQ QP + V+A + + + QP P + +
Sbjct: 2147 -GVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEA 2205
Query: 338 QPKLQ----KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQL 393
QP+L+ +A+ + PE ++ + + + Q E+E + Q + + PQ + +
Sbjct: 2206 QPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEA 2265
Query: 394 QQEAEPLKQVQPQVQPQAHSQPPRQ 418
+ + P+ + +P P P Q
Sbjct: 2266 SESSSPVPEDRPTPPPSPGGDTPHQ 2290
Score = 52.0 bits (123), Expect = 2e-06
Identities = 63/306 (20%), Positives = 124/306 (40%), Gaps = 25/306 (8%)
Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVED--KSDPPEGSEEAAEPRMDTPEDQ-DLPPCPED 237
P+ + + +++ + P D ++ P EEA E +T + + D P +
Sbjct: 1995 PESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDG 2054
Query: 238 I-AKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTP 296
+ A E A E E E E + SE+ +E G+ AQP++ + +
Sbjct: 2055 VEAPEAEEEAQEAEG-EVQEAEGEAHPESEDVDAQEAEGE----AQPESEGVEAPEAEGE 2109
Query: 297 DLLPEALEA-QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHL 354
E +EA + QP ++A + + + QP + Q + +AQ ++
Sbjct: 2110 AQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQ---DAEGEAQPESEGIEA 2166
Query: 355 VLQQKQVQPQLQQ----EAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQ 410
+++ QP+L+ EAE + Q + + ++G Q +L+ P + + Q +P+
Sbjct: 2167 QEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPE 2226
Query: 411 AHSQPPRQVQLQLQKQVQTQ----TYPQVHT---QAQPSVQPQEHPPAQVSVQPPEQTHE 463
P + + Q + + +TQ PQV Q++ + + P PP +
Sbjct: 2227 GVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGD 2286
Query: 464 QPHTQP 469
PH +P
Sbjct: 2287 TPHQRP 2292
Score = 33.5 bits (75), Expect = 0.91
Identities = 36/164 (21%), Positives = 67/164 (40%), Gaps = 12/164 (7%)
Query: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQ 444
++G + + EA+P + + + +Q + + + Q + + P+ +AQP +
Sbjct: 1832 AEGIEAPEAEGEAQPESEGVEAPEAEGDAQ---EAEGEAQPESEDVEAPEAEGEAQPESE 1888
Query: 445 PQEHPPAQVSVQP-------PEQTHE-QPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 496
E P A+ VQP PE E QP T+ +L + + +A +
Sbjct: 1889 DVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQ 1948
Query: 497 AGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
G + E + +Q + EE Q ES ++ E E +E G
Sbjct: 1949 EAEGQTQPESEVIESQEAEEEAQPESE-DVEALEVEVETQEAEG 1991
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 70.9 bits (172), Expect = 5e-12
Identities = 102/394 (25%), Positives = 132/394 (33%), Gaps = 50/394 (12%)
Query: 130 PGLAAPSLT-PPQLATPNLQQFFPQATRQSLLGP----PPVGVPMNPSQFNLSGRNPQKQ 184
P A PS+T PP A P+LQ P SL P PP + ++ Q S +P Q
Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424
Query: 185 ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRT 244
A S T R+ +S T P S PP+ P + P LP P
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPD------SPPLQAP--LSLPASPPLQTSLSPA 476
Query: 245 PAPEPEPCEASELPAKRLRSSEEPTEK-----EPPGQLQVKAQPQARMTVPKQTQTPDLL 299
+P P L A +S P PP + Q P + T P TP L
Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL- 535
Query: 300 PEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT-----SPEHL 354
+ LP P LQ + T P + + LQ T +P +
Sbjct: 536 ------ENLPSLAPPPLQTAS--APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587
Query: 355 VLQQKQVQPQLQQ---EAEPQKQVQPQVQPQAHSQGPRQVQLQQ-EAEPLKQVQPQVQPQ 410
Q P L + P + P P Q P + L +A P P + P
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPP--PQAPPXLALPPLQAPPSPPASPPLSPL 645
Query: 411 AHSQPPRQVQLQ---LQKQVQTQTYPQVHT----QAQPSVQPQEHPPAQVS---VQPPEQ 460
A P L LQ P V A P V P PP+Q PP Q
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
Query: 461 THEQPHTQPQVSLLA--PEQTPVVVHVCGLEMPP 492
P P +S A P Q P + L++PP
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739
Score = 62.4 bits (150), Expect = 2e-09
Identities = 124/507 (24%), Positives = 162/507 (31%), Gaps = 80/507 (15%)
Query: 45 SPPQAPLPMAV-SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRA---LLLQQLQGLDQF 100
SPP P A S PP Q L + L LQ L L LQ
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418
Query: 101 AMPPATYDTAGLTM-PTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL 159
P + LTM P T +L SP + P+ TPP +P LQ SL
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASL-----TSP--SRPASTPPD--SPPLQ------APLSL 463
Query: 160 LGPPPVGVPMNPSQFNLSGR---NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSE 216
PP+ ++P+ LS +P + + +S +P SS P+E +S S
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 217 EAAEPRMDTPEDQDLP---PCPEDIAKEKRT-------PAPEPEPCEA-----SELPAKR 261
+ + TP ++LP P P A T P P P P +A + P +
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583
Query: 262 LRSSEEPTEKEPPGQLQVKAQ-----PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 316
S P + PP Q P + + P P L L+A P P +
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643
Query: 317 QVQA---------QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 367
+ V P P VQ A SP Q P L
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS--ATPPSQAPPSL-- 699
Query: 368 EAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQ---------AHSQPPRQ 418
A P QV P P + P Q PL QV P + + PPR
Sbjct: 700 -AAPPLQVPPS-PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 419 VQLQLQKQVQTQTYPQVHTQAQPSVQPQEH-------PPAQVSVQPPEQTHEQPHTQPQV 471
L +Q P P +P PP Q PP Q P
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 817
Query: 472 SL------LAPEQTPVVVHVCGLEMPP 492
SL P Q P V+ L++PP
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPP 844
Score = 57.4 bits (137), Expect = 6e-08
Identities = 107/443 (24%), Positives = 143/443 (32%), Gaps = 42/443 (9%)
Query: 46 PPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPA 105
P PL ++S + P + LQ +S + + +L++ L+ A P
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 106 TYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPV 165
A LT P L NL A+ LT P L TP P S L PP
Sbjct: 524 QTPPASLTTPP--LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP- 580
Query: 166 GVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDT 225
P PS S P QA + ++ P + S P+ + PP+ A P +
Sbjct: 581 --PETPS----SIATPPPQAPPALASPPLQGLPSPPLSPL--ATPPPQAPPXLALPPLQA 632
Query: 226 PEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQA 285
P P A +P P P + L L++ P P +Q P A
Sbjct: 633 P--------PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP---VQAPFSPPA 681
Query: 286 RMTVPKQTQTPDLLPEALEAQVL-----PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
V P P +L A L P P + A Q P + + QV P
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQVPP- 739
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQ---PQAHSQGPRQVQLQQEA 397
A SP +V P L A P QV P P + P A
Sbjct: 740 -SPPASPPMSPS--ATPPPRVPPLL---AAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793
Query: 398 EPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQV-HTQAQPSVQPQEHPPAQVSVQ 456
P Q P Q P L PQ A P +Q PPA ++Q
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853
Query: 457 PPEQTHEQPHTQPQVSLLAPEQT 479
P + P P S+ P T
Sbjct: 854 APRR---PPTPGPDTSVSGPRLT 873
Score = 48.5 bits (114), Expect = 3e-05
Identities = 91/395 (23%), Positives = 133/395 (33%), Gaps = 48/395 (12%)
Query: 119 LGNLRGYGMASP---GLAAPSLTPPQLATPNLQQFFPQATRQSL---LGPPPVGVPMNPS 172
LG L +A+P G A + PP A L P + + L PP P +
Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355
Query: 173 QFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP 232
P QA S +T P + S QT+P P + P + P
Sbjct: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP------PIQVPHSLTSPSLQA------P 403
Query: 233 PCPEDIAKEKRTPAPEPEPCEASE-----LPAKRLRSSEEPTE--KEPPGQLQVKAQPQA 285
P P ++ + T + +A+ P + S P+ PP ++A
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463
Query: 286 RMTVPKQTQ-TPDLLPEALEAQVLPRFQPRVL---QVQAQVQSQTQPRIPSTDTQVQPKL 341
+ P QT +P + P + + P L QA + S P + + + P L
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 342 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLK 401
Q + T+P L P LQ + P + P P LQ PL
Sbjct: 524 QTPPASLTTPP-LENLPSLAPPPLQTASAPLTTPHLETPP-----CPAPCPLQAPPSPLT 577
Query: 402 QVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVS---VQPP 458
P+ P + + PP Q L P + P + P PP Q PP
Sbjct: 578 TPPPET-PSSIATPPPQAPPALAS-------PPLQGLPSPPLSPLATPPPQAPPXLALPP 629
Query: 459 EQTHEQPHTQPQVSLLA--PEQTPVVVHVCGLEMP 491
Q P P +S LA Q P + V L+ P
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664
Score = 45.4 bits (106), Expect = 2e-04
Identities = 77/342 (22%), Positives = 110/342 (32%), Gaps = 59/342 (17%)
Query: 162 PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP 221
P PV P S G QK R S+ T R ++ + P+ S +A
Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT----------EAPKRSALSAGA 160
Query: 222 RMDTPEDQDLPPCPEDIAKEKRT---------PAPEPEPCEASELPAKRLRSSEEPTEKE 272
R DT P P +A+ R PAP P +E P K + S+ E + E
Sbjct: 161 RRDTSGPTPGTPSPA-MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219
Query: 273 PPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS 332
P P AR +L + P P ++ ++ PR P+
Sbjct: 220 P--------SPAARRRPSAGGGLQRPASRSLSSSATPLSSP----ARSGPSARGTPRAPA 267
Query: 333 TDTQVQPK-LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQV 391
+Q +PK LQ Q +P P+K P + P + S
Sbjct: 268 HPSQPKPKGLQALRPPQVTP-------------------PRKDAAPALGPLSSSPLATPS 308
Query: 392 QLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPA 451
+A P+ P + PP A PS+Q PPA
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPS------PPLATPLPLAPPSPSAPPSLQTLPSPPA 362
Query: 452 QVSVQ-PPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 492
Q PP T P + + P Q P + L+ PP
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404
Score = 35.8 bits (81), Expect = 0.18
Identities = 86/318 (27%), Positives = 106/318 (33%), Gaps = 75/318 (23%)
Query: 42 LQQSP-PQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQF 100
LQ P P A LPM+ PPQ P AL LQ L
Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPP----------------------ALATPPLQALPS- 802
Query: 101 AMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQ-QFFPQA--TRQ 157
PPA++ P+A+L SP P PP LA P LQ P A T Q
Sbjct: 803 --PPASFPGQAPFSPSASL-------PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853
Query: 158 SLLGPPPVGVPMNPS----QFNLSGRNPQKQARTSSSTTPN---RKDSSSQTMPVEDKSD 210
+ PP G + S L+ P +R+ SST SSS T E+
Sbjct: 854 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 913
Query: 211 PPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP---------EPEPCEASELPAK- 260
G E A P D +L C A R PAP P P + P
Sbjct: 914 YDSGPEGGA--AASPPPDAELAACHP--AAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 969
Query: 261 ----RLRSSEEPTEKEP-PGQLQVKAQP-------------QARMTVPKQTQTPDLLPEA 302
+ +E P P PG L P A PKQ + +L A
Sbjct: 970 DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGA 1029
Query: 303 LEAQVLPRFQPRVLQVQA 320
L+A V+ R L + A
Sbjct: 1030 LQASVVQHLLSRTLLLAA 1047
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 70.9 bits (172), Expect = 5e-12
Identities = 110/462 (23%), Positives = 162/462 (35%), Gaps = 104/462 (22%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQ------------------------------ 33
+QQQQQ QQQQQQ QQ QQQQ QQQQ QQQ
Sbjct: 2718 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTP 2777
Query: 34 -QLLQLQQLLQQSPPQAPLPMA------------VSRGLPPQQPQQPLLNLQGTNSASLL 80
L+++Q+ Q PPQ P P A V PPQQ L + +LL
Sbjct: 2778 EHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALL 2837
Query: 81 NGSMLQRALLLQQLQGLDQFAMPPATYDTAGLT-MPTATLGNLRGYGMASPGLAAPSLTP 139
G+ + A A LT +PT+ L +P A +L
Sbjct: 2838 TGTTV-------------------ANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAK 2878
Query: 140 PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKD-- 197
P + + P A S P +PMN + +++ PQK A + P
Sbjct: 2879 PPVVS------VPAAVVSS---PGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQL 2929
Query: 198 -SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASE 256
Q + K+ P+ ++ A + Q P + PA + +
Sbjct: 2930 LKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPI 2989
Query: 257 LPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 316
A++L +++ Q+QV PQ V +QT + A +Q
Sbjct: 2990 SQAQKLAGAQQVQT-----QIQVAKLPQ---VVQQQTPVASIQQVASASQ---------- 3031
Query: 317 QVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQ 376
Q Q + TQ Q+ P + AQ V+QQK +Q Q+ A Q
Sbjct: 3032 QASPQTVALTQATAAGQQVQMIPAVTATAQ--------VVQQKLIQQQVVTTASAPLQTP 3083
Query: 377 PQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ 418
P +Q P + L+ P V+ + ++PP Q
Sbjct: 3084 GAPNP---AQVPASSDSPSQQPKLQMRVPAVRLKTPTKPPCQ 3122
Score = 70.5 bits (171), Expect = 7e-12
Identities = 119/525 (22%), Positives = 184/525 (35%), Gaps = 75/525 (14%)
Query: 16 QLQQLQQQQLQQQQ--LQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQG 73
Q+ L+ +++ +++ L QQ Q + Q PPQ P PPQQP PL Q
Sbjct: 2476 QVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPP------PPQQPPPPLPQPQA 2529
Query: 74 TNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLA 133
GS Q Q Q P P T G G G
Sbjct: 2530 A-------GSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTG---GSAAVLAGTI 2579
Query: 134 APSLTPPQLAT--------PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQA 185
S+T + T N P AT QS+ + P+ P G + Q
Sbjct: 2580 KTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSI--NKRLASPVAPGALTTPGGSAPAQV 2637
Query: 186 RTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 245
+ P S + P +G +L P + R+
Sbjct: 2638 -VHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTP----VQTPARSL 2692
Query: 246 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 305
P+ +LP K + P Q+ Q Q + +Q Q
Sbjct: 2693 VPQVSQATGVQLPGKTI----------TPAHFQLLRQQQQQQQQQQQQQ----------- 2731
Query: 306 QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL 365
Q + Q + Q Q Q + +Q ++P Q Q Q +A + +PEHL+ QKQ
Sbjct: 2732 QQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMP 2791
Query: 366 QQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQK 425
Q PQ Q P QP A QVQ+ Q ++P +Q PQ+ +P +
Sbjct: 2792 PQPPPPQAQSAPP-QPTA------QVQV-QTSQPPQQQSPQLTTVTAPRPGALLTGTTVA 2843
Query: 426 QVQTQTYPQVHT---QAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVV 482
+Q +V T QAQ +Q Q PAQV++ P + P + +P T +
Sbjct: 2844 NLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVV-----SVPAAVVSSPGVTTLP 2898
Query: 483 VHVCGLEMPPDAVEAGGGMEKTLPEPVGTQ----VSMEEIQNESA 523
++V G+ + + G + + +PV Q + + +Q + A
Sbjct: 2899 MNVAGISVAIGQPQKAAG-QTVVAQPVHMQQLLKLKQQAVQQQKA 2942
Score = 68.2 bits (165), Expect = 3e-11
Identities = 128/484 (26%), Positives = 175/484 (36%), Gaps = 89/484 (18%)
Query: 8 QQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQP 67
Q L+QQQQQ QQ QQQQ QQQQ QQQQ Q QQ S Q Q P
Sbjct: 2715 QLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTS-----------------QVQVP 2757
Query: 68 LLNLQGTNSASL-LNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYG 126
+ Q + A + G + L+ Q Q L PP + PTA
Sbjct: 2758 QIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQ-------- 2809
Query: 127 MASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQAR 186
+ + PPQ +P L ++ P P + + NL Q
Sbjct: 2810 -----VQVQTSQPPQQQSPQL---------TTVTAPRPGALLTGTTVANL-----QVARL 2850
Query: 187 TSSSTTPNRKDSSSQTMPVEDK----SDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 242
T T+ + QT + + PP S AA + +P LP I+
Sbjct: 2851 TRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAV--VSSPGVTTLPMNVAGIS--- 2905
Query: 243 RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEA 302
+P+ + A+ + + K+ Q Q QPQA Q P + +
Sbjct: 2906 -VAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQA-------AQGPAAVQQK 2957
Query: 303 LEAQVL--PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
+ AQ + P Q +V AQ +TQ +T KL Q QT + L
Sbjct: 2958 ITAQQITTPGAQQKVAYA-AQPALKTQ--FLTTPISQAQKLAGAQQVQTQIQVAKL---- 3010
Query: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQ--PQVQPQAHSQPPRQ 418
PQ+ Q+ P +Q QV + P+ V L Q +QVQ P V A
Sbjct: 3011 --PQVVQQQTPVASIQ-QVASASQQASPQTVALTQATAAGQQVQMIPAVTATA------- 3060
Query: 419 VQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQV--SVQPPEQTHEQPHTQPQVSLLAP 476
Q+ QK +Q Q V T + P P PAQV S P Q + P V L P
Sbjct: 3061 -QVVQQKLIQQQV---VTTASAPLQTPGAPNPAQVPASSDSPSQQPKLQMRVPAVRLKTP 3116
Query: 477 EQTP 480
+ P
Sbjct: 3117 TKPP 3120
Score = 47.8 bits (112), Expect = 5e-05
Identities = 96/444 (21%), Positives = 143/444 (32%), Gaps = 110/444 (24%)
Query: 228 DQDLPPCP------EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 281
D+ LPP E IAKEK+ A + + +++P +PP
Sbjct: 2469 DKPLPPIQVASLRAERIAKEKKALADQ--------------QKAQQPAVAQPP------- 2507
Query: 282 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP-- 339
PQ + P Q Q P LP+ A P P +Q Q Q Q QTQP+ + QP
Sbjct: 2508 PPQPQPPPPPQ-QPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAI 2566
Query: 340 ---------------------------------------------KLQKQAQTQTSPEHL 354
+ K+ + +P L
Sbjct: 2567 TTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGAL 2626
Query: 355 VLQQKQVQPQLQQEAEPQKQV------QPQVQPQAHSQGPRQV-----------QLQQEA 397
Q+ P + V P + A +QG R V L
Sbjct: 2627 TTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQ 2686
Query: 398 EPLKQVQPQVQ------------PQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQP 445
P + + PQV AH Q RQ Q Q Q+Q Q Q Q Q Q Q
Sbjct: 2687 TPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 2746
Query: 446 QEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTL 505
Q +QV V + + P V L PE + + L+MPP +
Sbjct: 2747 QTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHL-IKMQKQKLQMPPQPPPPQA--QSAP 2803
Query: 506 PEPVG-TQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSL-KVTILQSSDSRAFST 563
P+P QV + + + L + G A + ++T + +S +A
Sbjct: 2804 PQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQ 2863
Query: 564 VPLTPVPRPSDSVSSTPAATSTPS 587
+ T P+P+ + P S P+
Sbjct: 2864 MQ-TQAPQPAQVALAKPPVVSVPA 2886
Score = 36.2 bits (82), Expect = 0.14
Identities = 54/247 (21%), Positives = 93/247 (37%), Gaps = 42/247 (17%)
Query: 157 QSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQT-MPVEDKSDPPEGS 215
Q L+ G+P P L+G+ +Q S+ P + +S T +P PP G
Sbjct: 506 QQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGV 565
Query: 216 EEAA---------EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSE 266
AA +P++ + Q P K ++ P P P +S+LP + ++
Sbjct: 566 PTAALSSALQFAQQPQVVEAQTQLQIP-----VKTQQPNVPIPAP-PSSQLPIPPSQPAQ 619
Query: 267 EPTEKEPPGQLQVKAQ-----PQ----ARMTVPKQTQTPDLLPEALEAQVLP-------- 309
PG++QV+A PQ R+ V P LP + + + P
Sbjct: 620 LALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGP 679
Query: 310 ---------RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
R + + V S+T + S T+ Q Q +Q S + + +Q
Sbjct: 680 SPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQIT 739
Query: 361 VQPQLQQ 367
++ Q+ Q
Sbjct: 740 LENQVHQ 746
Score = 33.9 bits (76), Expect = 0.70
Identities = 73/292 (25%), Positives = 103/292 (35%), Gaps = 55/292 (18%)
Query: 363 PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ 422
PQ Q A Q+Q Q Q P S GP PL Q+ ++ P LQ
Sbjct: 520 PQAAQLAG-QRQSQQQYDP---STGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQ 575
Query: 423 LQKQ---VQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHE---QPHTQPQVSLLAP 476
+Q V+ QT Q+ + Q P PP+ PP Q + T +V + A
Sbjct: 576 FAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQAS 635
Query: 477 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 536
+ + + V +P D P P+ T S + S G
Sbjct: 636 QLSSLPQMVASTRLPVDPA-------PPCPRPLPTS-STSSLAPVSGSG----------- 676
Query: 537 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 596
PG A S V S+ ++A S V R V+S P +P++ A
Sbjct: 677 --PGPSPARSS-PVNRPSSATNKALSPV----TSRTPGVVASAPTKPQSPAQNA------ 723
Query: 597 ICKASCSSQQEFQDHMSEP-----QHQQRLGEIQH---MSQACLLSLLPVPR 640
SSQ QD ++E Q QR+ E++ SQ L L PR
Sbjct: 724 -----TSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPR 770
Score = 33.9 bits (76), Expect = 0.70
Identities = 48/183 (26%), Positives = 72/183 (39%), Gaps = 17/183 (9%)
Query: 17 LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP--PQQPQQPLLNLQGT 74
LQ QQ Q+ + Q Q Q ++ QQ P P+P S LP P QP Q L++ T
Sbjct: 574 LQFAQQPQVVEAQTQLQIPVKTQQ------PNVPIPAPPSSQLPIPPSQPAQLALHVP-T 626
Query: 75 NSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGL-TMPTATLGNLRGYGMA-SPGL 132
+ S L L Q+ + + PA L T T++L + G G SP
Sbjct: 627 PGKVQVQASQLSS---LPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPAR 683
Query: 133 AAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTT 192
++P P L P +R + P +P+Q S ++ + T T
Sbjct: 684 SSPVNRPSSATNKALS---PVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQITL 740
Query: 193 PNR 195
N+
Sbjct: 741 ENQ 743
Score = 33.9 bits (76), Expect = 0.70
Identities = 62/275 (22%), Positives = 89/275 (32%), Gaps = 62/275 (22%)
Query: 125 YGMASPG--LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 182
YG G +A PS PP+ A P PQ L G PP+ NP+
Sbjct: 1432 YGQKPEGRTVAFPSTHPPRTAAPTTASAAPQG---PLRGRPPIAT---------FSANPE 1479
Query: 183 KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 242
+A + P + +S + P + P S AA
Sbjct: 1480 AKA----AAAPFQTSQASASAP---RHQPASASSTAA----------------------- 1509
Query: 243 RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEA 302
P ++L A+ + P + P QPQA Q+ P L
Sbjct: 1510 -------SPAHPAKLRAQTTAQASTPGQPPP--------QPQAPSHAAGQSALPQRL--V 1552
Query: 303 LEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ 362
L +Q R + AQ+ S T P+ + LQ Q T H L+Q
Sbjct: 1553 LPSQAQARLPSGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTL-SHSQLRQLTAG 1611
Query: 363 PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEA 397
LQ + + V QP + GP +Q +A
Sbjct: 1612 QPLQLQGSVLQIVSAPGQPYLRAPGPVVMQTVSQA 1646
Score = 32.0 bits (71), Expect = 2.7
Identities = 52/232 (22%), Positives = 84/232 (36%), Gaps = 36/232 (15%)
Query: 237 DIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEK--EPPGQLQVKAQPQARM-----TV 289
++ +K+ P E S PA R +++ + +P +Q +P+ R T
Sbjct: 1391 ELLSKKKIPRKLMEEISTSAAPAARPAAAKLKASRLFQP---VQYGQKPEGRTVAFPSTH 1447
Query: 290 PKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 349
P +T P A + + R + ++ P S + P+ Q + + T
Sbjct: 1448 PPRTAAPTTASAAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPRHQPASASST 1507
Query: 350 --SPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQ------------ 395
SP H + + Q A+ QP QPQA S Q L Q
Sbjct: 1508 AASPAH------PAKLRAQTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVLPSQAQARL 1561
Query: 396 ---EAEPLKQVQPQVQPQAH-SQPPRQVQLQLQKQVQTQTYPQVH--TQAQP 441
E + Q+ PQ+ +QP V LQ Q T ++ Q+ T QP
Sbjct: 1562 PSGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQP 1613
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 70.5 bits (171), Expect = 7e-12
Identities = 76/241 (31%), Positives = 106/241 (43%), Gaps = 24/241 (9%)
Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
S + ++K+ P Q+ V A MT Q TP + + L+ QVL P+ LQ Q Q
Sbjct: 75 SPKSSDKQRPLQVPVSV---AMMT--PQVITPQQMQQILQQQVL---SPQQLQALLQQQQ 126
Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
+ Q +LQ+ + Q HL L Q+Q Q Q QQ+ + Q+Q Q Q Q Q
Sbjct: 127 AVMLQ--------QQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 178
Query: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQ-VQTQTYPQVHTQAQPSV 443
Q +Q Q QQ+ P KQ + Q Q Q Q QL Q+Q +Q Q Q Q S+
Sbjct: 179 QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ--QQHLLSL 236
Query: 444 QPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEK 503
Q Q +S+ PP Q + PQ L E + V G+ D GG++
Sbjct: 237 QRQ----GLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDL 291
Query: 504 T 504
T
Sbjct: 292 T 292
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ P + QQ
Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 206
Query: 65 QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113
QQ L Q LL LQ+ LL Q QGL Q A+P + AGL+
Sbjct: 207 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 262
Score = 57.8 bits (138), Expect = 5e-08
Identities = 67/279 (24%), Positives = 115/279 (41%), Gaps = 36/279 (12%)
Query: 301 EALEA--QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
+AL+A Q+L + Q L+ Q ++P + + P++ Q Q + VL
Sbjct: 56 QALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSP 115
Query: 359 KQVQPQLQQEAE---PQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQP 415
+Q+Q LQQ+ Q+Q+Q + Q + +Q QQ+ + +Q Q Q Q Q Q
Sbjct: 116 QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175
Query: 416 PRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLA 475
+Q Q Q Q+Q Q Q +P + Q Q Q+ A + +Q + Q Q LL+
Sbjct: 176 QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 235
Query: 476 PEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 535
++ ++ +PP + LP +Q+ GL E +
Sbjct: 236 LQRQGLI------SIPPG--------QAALP-----------VQSLPQAGLSPAEIQQLW 270
Query: 536 REMPGVWG------AGGSLKVTILQSSDSRAFSTVPLTP 568
+E+ GV G L +T SS + + +T +P
Sbjct: 271 KEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASP 309
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%)
Query: 5 QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
QQQQ + QQQQLQ+ QQ+QL Q LQQQQ Q QQ QQ Q +
Sbjct: 123 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 182
Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121
QQ QQ G + Q+ L QQL Q L +
Sbjct: 183 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 235
Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155
L+ G+ S PG AA SL L+ +QQ + + T
Sbjct: 236 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 274
Score = 33.5 bits (75), Expect = 0.91
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 6/86 (6%)
Query: 12 QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAV--SRGLPPQQPQQPLL 69
QQQQ LQ +Q LQQQ L + +Q P Q P+ +A+ + + PQQ QQ +L
Sbjct: 53 QQQQALQAARQLLLQQQT---SGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQ-IL 108
Query: 70 NLQGTNSASLLNGSMLQRALLLQQLQ 95
Q + L Q+A++LQQ Q
Sbjct: 109 QQQVLSPQQLQALLQQQQAVMLQQQQ 134
Score = 31.2 bits (69), Expect = 4.5
Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58
QQ QQ LQQQ QQLQ LQQQQ + QLQ+ ++ Q L + +
Sbjct: 102 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155
Query: 59 LPPQQPQQ 66
QQ QQ
Sbjct: 156 QQQQQQQQ 163
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 70.1 bits (170), Expect = 9e-12
Identities = 82/297 (27%), Positives = 107/297 (36%), Gaps = 51/297 (17%)
Query: 198 SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASEL 257
+ Q + + PP P M PP P + R P P P P
Sbjct: 22 AQQQALRFRGPAPPPNAVMRGPPPLMR-------PPPPFGMM---RGPPPPPRP------ 65
Query: 258 PAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP---RFQPR 314
P R PPG + P P Q P +P + + P F P
Sbjct: 66 PFGRPPFDPNMPPMPPPGGIP---PPMG----PPHLQRPPFMPPPMSSMPPPPGMMFPPG 118
Query: 315 VLQVQAQVQSQTQPRIPSTDT-QVQPKLQK------QAQTQ----TSPEHL-VLQQKQVQ 362
+ V A P +P T+ V+ K A+T+ T P+ + V+QQ ++
Sbjct: 119 MPPVTAP----GTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELT 174
Query: 363 PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ 422
P L +A+ Q Q Q Q Q QA +Q Q Q Q +A Q Q Q Q QA +Q Q Q Q
Sbjct: 175 PMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQA----QAQAQAQAQAQAQAQAQAQAQ 230
Query: 423 LQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 479
Q Q Q Q QV Q Q VQ Q V P + P S P T
Sbjct: 231 AQAQAQAQAQAQVQAQVQAQVQAQ-----AVGASTPTTSSPAPAVSTSTSSSTPSST 282
Score = 67.8 bits (164), Expect = 4e-11
Identities = 124/528 (23%), Positives = 182/528 (34%), Gaps = 113/528 (21%)
Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 220
GPPP+ P P F + R P R P D + MP PP G
Sbjct: 42 GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96
Query: 221 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV- 279
P P +PP P + P P A PA K P G++
Sbjct: 97 PPFMPPPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150
Query: 280 -KAQPQARMTVP---KQTQTPDLLPE-ALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334
++ T P K Q +L P A +AQV + Q + Q QAQ Q+Q Q +
Sbjct: 151 NARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQA-QAQAQAQAQAQAQ---AQ 206
Query: 335 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQA----------- 383
Q Q + Q QAQ Q + Q Q Q Q Q +A+ Q QVQ QVQ QA
Sbjct: 207 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSP 266
Query: 384 --------HSQGPRQVQ---------LQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQ 426
S P Q + P Q Q + + P V
Sbjct: 267 APAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTA 326
Query: 427 VQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVC 486
QT PQ H PQ PPA PH+ PQ + P PV+V
Sbjct: 327 TPVQTVPQPH--------PQTLPPA------------VPHSVPQPTTAIPAFPPVMV--- 363
Query: 487 GLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGG 546
PP V G +P P+ M+ + +C + +PG+
Sbjct: 364 ----PPFRVPLPG-----MPIPLPGVAMMQIV----SCPYVKTVATTKTGVLPGM----- 405
Query: 547 SLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPA--ATSTPSKQALQFFCYICKASCSS 604
P+ P+ P +++++PA A +T + ++ K +
Sbjct: 406 ----------------APPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYN 449
Query: 605 QQEFQDHMSEPQHQQRLGEIQHMSQACLL--SLLPVPRDVLETEDEEP 650
+ + +PQ + +++ + + S P+P +ETE+E+P
Sbjct: 450 NRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLP---METEEEDP 494
Score = 45.4 bits (106), Expect = 2e-04
Identities = 79/391 (20%), Positives = 121/391 (30%), Gaps = 50/391 (12%)
Query: 26 QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84
+ ++ +L QQ + AP P AV RG PP +P P ++G
Sbjct: 10 ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPR----- 64
Query: 85 LQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLAT 144
F PP +D MP G P + P L P
Sbjct: 65 -------------PPFGRPP--FDPNMPPMPPP--------GGIPPPMGPPHLQRPPFMP 101
Query: 145 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 204
P + P G PPV P P+ P + + TP+ K
Sbjct: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPAL-------PPTEEIWVENKTPDGKVYYYNART 154
Query: 205 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
E P+G + + + TP + + A +A + A+
Sbjct: 155 RESAWTKPDGVKVIQQSEL-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQ 212
Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
++ + + Q Q +AQ QA+ Q Q + ++AQ + P V +
Sbjct: 213 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVST 272
Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
T PS+ T AQT ++P Q Q A P V
Sbjct: 273 STSSSTPSSTTSTTTTATSVAQTVSTP----TTQDQTPSSAVSVATPTVSVS-------- 320
Query: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQP 415
+ P +Q +P Q P P + QP
Sbjct: 321 TPAPTATPVQTVPQPHPQTLPPAVPHSVPQP 351
Score = 33.5 bits (75), Expect = 0.91
Identities = 75/319 (23%), Positives = 109/319 (34%), Gaps = 39/319 (12%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62
Q Q Q Q Q Q Q Q Q Q Q+Q Q Q+Q Q + S P P AVS
Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277
Query: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMP------PATYDTAGLTMP- 115
P T +A+ + ++ Q A P PA T T+P
Sbjct: 278 TPSS---TTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQ 334
Query: 116 --TATLGNLRGYGMASPGLAAPS----LTPP-QLATPNLQQFFPQATRQSLLGPPPVGVP 168
TL + + P A P+ + PP ++ P + P ++ P V
Sbjct: 335 PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTV 394
Query: 169 MNPSQFNLSGR--------NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 220
L G +PQ S +T S T + E
Sbjct: 395 ATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLE 454
Query: 221 PRMDTPED-QDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEK 271
+ P++ ++ E I + + P+ EP P E E P K ++ EE TE+
Sbjct: 455 STWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEE 514
Query: 272 EPPGQLQVKAQPQARMTVP 290
E Q KA+P A +P
Sbjct: 515 EKAAQ---KAKPVATAPIP 530
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 68.2 bits (165), Expect = 3e-11
Identities = 70/225 (31%), Positives = 97/225 (43%), Gaps = 19/225 (8%)
Query: 281 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
A P + + Q TP + + L+ QVL P+ LQ Q Q + Q +
Sbjct: 111 AVPVSVAMMTPQVITPQQMQQILQQQVL---SPQQLQALLQQQQAVMLQ--------QQQ 159
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
LQ+ + Q HL L Q+Q Q Q QQ+ + Q+Q Q Q Q Q Q +Q Q QQ+ P
Sbjct: 160 LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 219
Query: 401 KQVQPQVQPQAHSQPPRQVQLQLQKQ-VQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPE 459
KQ + Q Q Q Q QL Q+Q +Q Q Q Q S+Q Q +S+ PP
Sbjct: 220 KQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ--QQHLLSLQRQ----GLISI-PPG 272
Query: 460 QTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKT 504
Q + PQ L E + V G+ D GG++ T
Sbjct: 273 QAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLT 317
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ Q QQ QQ P + QQ
Sbjct: 177 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 231
Query: 65 QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113
QQ L Q LL LQ+ LL Q QGL Q A+P + AGL+
Sbjct: 232 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 287
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%)
Query: 5 QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
QQQQ + QQQQLQ+ QQ+QL Q LQQQQ Q QQ QQ Q +
Sbjct: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 207
Query: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121
QQ QQ G + Q+ L QQL Q L +
Sbjct: 208 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 260
Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155
L+ G+ S PG AA SL L+ +QQ + + T
Sbjct: 261 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 299
Score = 35.4 bits (80), Expect = 0.24
Identities = 49/168 (29%), Positives = 66/168 (39%), Gaps = 27/168 (16%)
Query: 274 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 325
P QLQ Q Q + + +Q Q L + L+ Q + Q + Q Q Q Q Q
Sbjct: 140 PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 199
Query: 326 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHS 385
Q Q Q + Q+Q Q Q P +Q+Q Q Q QQ A Q Q Q+
Sbjct: 200 QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL------ 246
Query: 386 QGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYP 433
Q+Q Q+ + L +Q Q S PP Q L +Q Q P
Sbjct: 247 ---LQMQQLQQQQHLLSLQRQ---GLISIPPGQAALPVQSLPQAGLSP 288
Score = 34.7 bits (78), Expect = 0.41
Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 15/148 (10%)
Query: 280 KAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 339
K Q Q + + +Q Q + + Q + Q + Q Q Q Q Q Q + +
Sbjct: 166 KQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQ 225
Query: 340 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEP 399
+ Q+Q Q Q + + LV QQ+ +Q Q Q+ + +Q QG + Q A P
Sbjct: 226 QQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ--------RQGLISIPPGQAALP 277
Query: 400 LKQVQPQVQPQAHSQPPRQVQLQLQKQV 427
++ + PQA P ++Q QL K+V
Sbjct: 278 VQSL-----PQA-GLSPAEIQ-QLWKEV 298
Score = 31.2 bits (69), Expect = 4.5
Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58
QQ QQ LQQQ QQLQ LQQQQ + QLQ+ ++ Q L + +
Sbjct: 127 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180
Query: 59 LPPQQPQQ 66
QQ QQ
Sbjct: 181 QQQQQQQQ 188
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 68.2 bits (165), Expect = 3e-11
Identities = 66/238 (27%), Positives = 93/238 (39%), Gaps = 45/238 (18%)
Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
LQ + + + L LQ +Q Q Q QQ+ P PQ PQA SQ +Q PL
Sbjct: 169 LQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQ--------PL 220
Query: 401 KQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQ 460
+ PQ P A QPP QLQ+ Q Q + Q H+ +Q QP P Q S PP
Sbjct: 221 QPTPPQQPPPASQQPPAPTS-QLQQAPQPQQH-QPHSHSQNQNQPS---PTQQSSSPP-- 273
Query: 461 THEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQN 520
++P P L +P P + + + A A +M I +
Sbjct: 274 --QKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAA--------------AAMSSIAS 317
Query: 521 ESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSS 578
A G N + GV G ++ ++ + T+PL P P PS +S
Sbjct: 318 SQAFG-------NALSSLQGVTG-------QLVTNAQGQIIGTIPLMPNPGPSSQAAS 361
Score = 45.1 bits (105), Expect = 3e-04
Identities = 46/136 (33%), Positives = 54/136 (39%), Gaps = 11/136 (8%)
Query: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
Q Q QLQQLQ Q QQQQ QQQQ Q PQAP + + L P P
Sbjct: 167 QNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAP-SQSQQQPLQPTPP 225
Query: 65 QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRG 124
QQP Q + + S LQ+A QQ Q T + P G
Sbjct: 226 QQPPPASQQPPAPT----SQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPG 281
Query: 125 YGMASPGLAAPSLTPP 140
+G+ SP LTPP
Sbjct: 282 HGLPSP------LTPP 291
Score = 43.1 bits (100), Expect = 0.001
Identities = 64/289 (22%), Positives = 100/289 (34%), Gaps = 40/289 (13%)
Query: 112 LTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNP 171
LT+PTA L N++ G+ + A +T P Q+L + +
Sbjct: 139 LTLPTANLTNIQ--GLVAAAAAGGIMTLP---------------LQNLQATSSLNSQLQQ 181
Query: 172 SQFNLSGRNPQKQARTSSSTTPN-----RKDSSSQTMPVE--DKSDPPEGSEEAAEPRMD 224
Q L + Q+Q + ST + + S SQ P++ PP S++ P
Sbjct: 182 LQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAP--- 238
Query: 225 TPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEE---PTEKEPPGQLQVKA 281
T + Q P + +P P + S P ++ S P+ PP LQ+
Sbjct: 239 TSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVN 298
Query: 282 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 341
P A + L Q Q+ Q Q IP P
Sbjct: 299 NPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIP---LMPNPGP 355
Query: 342 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ---KQVQPQVQPQAHSQG 387
QA + T LQ + + PQL A+ Q + Q+ P ++QG
Sbjct: 356 SSQAASGTQG----LQVQPITPQLLTNAQGQIIATVIGNQILPVINTQG 400
Score = 43.1 bits (100), Expect = 0.001
Identities = 75/318 (23%), Positives = 111/318 (34%), Gaps = 45/318 (14%)
Query: 69 LNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMA 128
L LQ + S LN + Q L LQQ Q Q PP+T
Sbjct: 164 LPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQ------------------HP 205
Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 188
P APS + Q P Q P A++Q PP P + Q + PQ Q
Sbjct: 206 QPAPQAPSQSQQQPLQPTPPQQPPPASQQ----PP---APTSQLQ-----QAPQPQQHQP 253
Query: 189 SSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPE 248
S + N+ +Q P + S PP+ ++ + +P PP P +
Sbjct: 254 HSHSQNQ----NQPSPTQQSSSPPQKPSQSPGHGLPSPL---TPPNPLQLVNNPLASQAA 306
Query: 249 PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL 308
S + + + + + + GQL AQ Q T+P P+ P + A
Sbjct: 307 AAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLM---PNPGPSSQAASGT 363
Query: 309 PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE 368
Q + + Q +Q Q Q+ P + Q T SP ++ Q Q Q
Sbjct: 364 QGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGIT-LSP----IKPGQQLHQPSQT 418
Query: 369 AEPQKQVQPQVQPQAHSQ 386
+ Q Q + AHSQ
Sbjct: 419 SVGQAASQGNLLHLAHSQ 436
Score = 37.4 bits (85), Expect = 0.063
Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 4/78 (5%)
Query: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPP---QAPLPMAVSRGLP 60
QQQQQQ QQ Q Q Q QQQ LQ QQ PP Q P P + + P
Sbjct: 188 QQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQ-PTPPQQPPPASQQPPAPTSQLQQAP 246
Query: 61 PQQPQQPLLNLQGTNSAS 78
Q QP + Q N S
Sbjct: 247 QPQQHQPHSHSQNQNQPS 264
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 67.8 bits (164), Expect = 4e-11
Identities = 79/321 (24%), Positives = 122/321 (38%), Gaps = 27/321 (8%)
Query: 180 NPQKQARTSSSTTPNRKDSS--SQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPED 237
N +++ + +S T + SS ++T + + P EG E+++ R E P+D
Sbjct: 93 NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSS---DPKD 149
Query: 238 IAKEKRT-----PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQ 292
I ++ R+ P+P+ ++ +++ ++ P + P G V P + Q
Sbjct: 150 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG---VTPAPSSAPPGTPQ 206
Query: 293 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352
TP P A V P+ P Q Q Q+ T P +P T Q P L Q P
Sbjct: 207 LPTPGPTPSA--TAVPPQGSPTASQAPNQPQAPTAP-VPHTHIQQAPALHPQRPPSPHPP 263
Query: 353 HLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAH 412
+QP +P QP H QGP Q L+ P PQ
Sbjct: 264 PHPSPHPPLQPLTGSAGQP--SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP---PQPF 318
Query: 413 SQPPRQVQLQLQKQVQ-TQTYPQVHTQ---AQPSVQPQEHPPAQ-VSVQPPEQTH-EQPH 466
PP+ Q Q YP Q +Q ++Q Q+ P Q + P H + P
Sbjct: 319 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 378
Query: 467 TQPQVSLLAPEQTPVVVHVCG 487
T P L AP+ H+ G
Sbjct: 379 TTPIPQLPAPQAHKHPPHLSG 399
Score = 55.5 bits (132), Expect = 2e-07
Identities = 98/449 (21%), Positives = 142/449 (31%), Gaps = 72/449 (16%)
Query: 176 LSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSD-----PPEGSEEAAEPRMDTPEDQD 230
L + P QA T + P+ + +P + PP+GS A++ P
Sbjct: 180 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ----APNQPQ 235
Query: 231 LPPCP--------EDIAKEKRTPAPEPEPCEASELPAKRLRSS----EEPTEKEPPGQLQ 278
P P +R P+P P P + P + L S P+ +PP Q
Sbjct: 236 APTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ 295
Query: 279 VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQ 338
P + P P L P+ Q QA + + P T Q+
Sbjct: 296 GPPGPHSLQAGPLLQHPGPPQPFGLP--------PQASQGQAPLGTSPAAAYPHTSLQL- 346
Query: 339 PKLQKQAQTQTSPEHLVLQQKQV-QPQLQQEAEPQKQVQPQVQPQAHSQ-----GPRQVQ 392
P Q Q+Q P L + P ++ P + PQAH GP
Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPP--PTTPIPQLPAPQAHKHPPHLSGPSPFS 404
Query: 393 LQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQ 452
+ P ++P H PP LQ Q+Q P Q Q Q PP
Sbjct: 405 MNANLPPPPALKPLSSLSTH-HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 463
Query: 453 VSVQPPEQTHEQPHTQP--QVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVG 510
S PP H+ P Q + P+ C P + G P G
Sbjct: 464 AS-HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC----PSTSTPPAGPGTSAQPPCSG 518
Query: 511 TQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVP 570
S I S+C L + + A L ++ P +P P
Sbjct: 519 AAASGGSIAGGSSCPLPTVQIKEEA-----------------LDDAEE------PESP-P 554
Query: 571 RPSDSVSSTPAATSTPS--KQALQFFCYI 597
P S S P TPS Q+ +F+ ++
Sbjct: 555 PPPRSPSPEPTVVDTPSHASQSARFYKHL 583
Score = 42.0 bits (97), Expect = 0.003
Identities = 92/432 (21%), Positives = 133/432 (30%), Gaps = 87/432 (20%)
Query: 46 PPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQR-------ALLLQQLQGLD 98
PP PL + + P Q PL SL G +LQ L Q QG
Sbjct: 270 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 329
Query: 99 QF-AMPPATYDTAGLTMPTATLG----------NLRGYGMASPGLAAPSLTP-PQLATPN 146
P A Y L +P + L +A P + P TP PQL P
Sbjct: 330 PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ 389
Query: 147 LQQFFPQATRQS------LLGPPPVGVPM-----------NPSQFNLSGRNPQKQARTSS 189
+ P + S L PPP P+ +P L PQ Q SS
Sbjct: 390 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM---PQSQPLPSS 446
Query: 190 STTPNRKDSSSQTMPVEDKSDPPEGSEEAAE----------------------PRMDTPE 227
P + SQ +P S PP G + A P TP
Sbjct: 447 PAQPPGL-TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP 505
Query: 228 ----DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 283
PPC A P ++ + L +EEP PP P
Sbjct: 506 AGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--------P 557
Query: 284 QARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQK 343
++ P TP A ++ + R A+ P S KL K
Sbjct: 558 RSPSPEPTVVDTPS---HASQSARFYKHLDRGYNSCARTDLYFMPLAGS-------KLAK 607
Query: 344 QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQV 403
+ + +QK + ++E E +K+ + + + + + R + A +
Sbjct: 608 KREEAIEKAKREAEQKARE---EREREKEKEKEREREREREREAERAAKASSSAHEGRLS 664
Query: 404 QPQVQPQAHSQP 415
PQ+ H +P
Sbjct: 665 DPQLSGPGHMRP 676
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 67.8 bits (164), Expect = 4e-11
Identities = 79/321 (24%), Positives = 122/321 (38%), Gaps = 27/321 (8%)
Query: 180 NPQKQARTSSSTTPNRKDSS--SQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPED 237
N +++ + +S T + SS ++T + + P EG E+++ R E P+D
Sbjct: 647 NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSS---DPKD 703
Query: 238 IAKEKRT-----PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQ 292
I ++ R+ P+P+ ++ +++ ++ P + P G V P + Q
Sbjct: 704 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG---VTPAPSSAPPGTPQ 760
Query: 293 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352
TP P A V P+ P Q Q Q+ T P +P T Q P L Q P
Sbjct: 761 LPTPGPTPSA--TAVPPQGSPTASQAPNQPQAPTAP-VPHTHIQQAPALHPQRPPSPHPP 817
Query: 353 HLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAH 412
+QP +P QP H QGP Q L+ P PQ
Sbjct: 818 PHPSPHPPLQPLTGSAGQP--SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP---PQPF 872
Query: 413 SQPPRQVQLQLQKQVQ-TQTYPQVHTQ---AQPSVQPQEHPPAQ-VSVQPPEQTH-EQPH 466
PP+ Q Q YP Q +Q ++Q Q+ P Q + P H + P
Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932
Query: 467 TQPQVSLLAPEQTPVVVHVCG 487
T P L AP+ H+ G
Sbjct: 933 TTPIPQLPAPQAHKHPPHLSG 953
Score = 55.5 bits (132), Expect = 2e-07
Identities = 98/449 (21%), Positives = 142/449 (31%), Gaps = 72/449 (16%)
Query: 176 LSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSD-----PPEGSEEAAEPRMDTPEDQD 230
L + P QA T + P+ + +P + PP+GS A++ P
Sbjct: 734 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ----APNQPQ 789
Query: 231 LPPCP--------EDIAKEKRTPAPEPEPCEASELPAKRLRSS----EEPTEKEPPGQLQ 278
P P +R P+P P P + P + L S P+ +PP Q
Sbjct: 790 APTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ 849
Query: 279 VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQ 338
P + P P L P+ Q QA + + P T Q+
Sbjct: 850 GPPGPHSLQAGPLLQHPGPPQPFGLP--------PQASQGQAPLGTSPAAAYPHTSLQL- 900
Query: 339 PKLQKQAQTQTSPEHLVLQQKQV-QPQLQQEAEPQKQVQPQVQPQAHSQ-----GPRQVQ 392
P Q Q+Q P L + P ++ P + PQAH GP
Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPP--PTTPIPQLPAPQAHKHPPHLSGPSPFS 958
Query: 393 LQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQ 452
+ P ++P H PP LQ Q+Q P Q Q Q PP
Sbjct: 959 MNANLPPPPALKPLSSLSTH-HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017
Query: 453 VSVQPPEQTHEQPHTQP--QVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVG 510
S PP H+ P Q + P+ C P + G P G
Sbjct: 1018 AS-HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC----PSTSTPPAGPGTSAQPPCSG 1072
Query: 511 TQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVP 570
S I S+C L + + A L ++ P +P P
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEA-----------------LDDAEE------PESP-P 1108
Query: 571 RPSDSVSSTPAATSTPS--KQALQFFCYI 597
P S S P TPS Q+ +F+ ++
Sbjct: 1109 PPPRSPSPEPTVVDTPSHASQSARFYKHL 1137
Score = 50.4 bits (119), Expect = 7e-06
Identities = 94/452 (20%), Positives = 154/452 (34%), Gaps = 74/452 (16%)
Query: 163 PPVGVPMNPSQF----------NLSGRNPQKQARTSSSTTPNRKDSSSQ-------TMPV 205
PP+ P++P F LSG++ + R+ S + R Q T P+
Sbjct: 543 PPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPI 602
Query: 206 -EDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
ED S AA + + + + + + +E +P + +R +
Sbjct: 603 NEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNK--------RQREKV 654
Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
+ + E + + K Q +R P + + ++ + P+ + Q
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE--GSSDPKDID---QDNR 709
Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
T P IPS ++ + +S + +LQ + Q P P PQ
Sbjct: 710 STSPSIPSPQ-------DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762
Query: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQ 444
+ GP V PQ P A SQ P Q Q T P H Q P++
Sbjct: 763 TPGP--------TPSATAVPPQGSPTA-SQAPN------QPQAPTAPVPHTHIQQAPALH 807
Query: 445 PQE----HPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGG 500
PQ HPP S PP Q QP AP +H G P +++AG
Sbjct: 808 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPS----APSHAQPPLHGQG-PPGPHSLQAGPL 862
Query: 501 MEKT-LPEPVGTQVSMEEIQNESACGLD-VGECENRAREMPGVWGAGGSLKVTILQSSDS 558
++ P+P G + + Q ++ G + + ++P A LQS
Sbjct: 863 LQHPGPPQPFG--LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSA--------LQSQQP 912
Query: 559 RAFSTVPLTPVPRPSDSVSSTPAATSTPSKQA 590
+P P+ P T P+ QA
Sbjct: 913 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA 944
Score = 42.0 bits (97), Expect = 0.003
Identities = 92/432 (21%), Positives = 133/432 (30%), Gaps = 87/432 (20%)
Query: 46 PPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQR-------ALLLQQLQGLD 98
PP PL + + P Q PL SL G +LQ L Q QG
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 883
Query: 99 QF-AMPPATYDTAGLTMPTATLG----------NLRGYGMASPGLAAPSLTP-PQLATPN 146
P A Y L +P + L +A P + P TP PQL P
Sbjct: 884 PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ 943
Query: 147 LQQFFPQATRQS------LLGPPPVGVPM-----------NPSQFNLSGRNPQKQARTSS 189
+ P + S L PPP P+ +P L PQ Q SS
Sbjct: 944 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM---PQSQPLPSS 1000
Query: 190 STTPNRKDSSSQTMPVEDKSDPPEGSEEAAE----------------------PRMDTPE 227
P + SQ +P S PP G + A P TP
Sbjct: 1001 PAQPPGL-TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP 1059
Query: 228 ----DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 283
PPC A P ++ + L +EEP PP P
Sbjct: 1060 AGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--------P 1111
Query: 284 QARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQK 343
++ P TP A ++ + R A+ P S KL K
Sbjct: 1112 RSPSPEPTVVDTPS---HASQSARFYKHLDRGYNSCARTDLYFMPLAGS-------KLAK 1161
Query: 344 QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQV 403
+ + +QK + ++E E +K+ + + + + + R + A +
Sbjct: 1162 KREEAIEKAKREAEQKARE---EREREKEKEKEREREREREREAERAAKASSSAHEGRLS 1218
Query: 404 QPQVQPQAHSQP 415
PQ+ H +P
Sbjct: 1219 DPQLSGPGHMRP 1230
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 67.8 bits (164), Expect = 4e-11
Identities = 79/321 (24%), Positives = 122/321 (38%), Gaps = 27/321 (8%)
Query: 180 NPQKQARTSSSTTPNRKDSS--SQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPED 237
N +++ + +S T + SS ++T + + P EG E+++ R E P+D
Sbjct: 647 NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSS---DPKD 703
Query: 238 IAKEKRT-----PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQ 292
I ++ R+ P+P+ ++ +++ ++ P + P G V P + Q
Sbjct: 704 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG---VTPAPSSAPPGTPQ 760
Query: 293 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352
TP P A V P+ P Q Q Q+ T P +P T Q P L Q P
Sbjct: 761 LPTPGPTPSA--TAVPPQGSPTASQAPNQPQAPTAP-VPHTHIQQAPALHPQRPPSPHPP 817
Query: 353 HLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAH 412
+QP +P QP H QGP Q L+ P PQ
Sbjct: 818 PHPSPHPPLQPLTGSAGQP--SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP---PQPF 872
Query: 413 SQPPRQVQLQLQKQVQ-TQTYPQVHTQ---AQPSVQPQEHPPAQ-VSVQPPEQTH-EQPH 466
PP+ Q Q YP Q +Q ++Q Q+ P Q + P H + P
Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932
Query: 467 TQPQVSLLAPEQTPVVVHVCG 487
T P L AP+ H+ G
Sbjct: 933 TTPIPQLPAPQAHKHPPHLSG 953
Score = 55.5 bits (132), Expect = 2e-07
Identities = 98/449 (21%), Positives = 142/449 (31%), Gaps = 72/449 (16%)
Query: 176 LSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSD-----PPEGSEEAAEPRMDTPEDQD 230
L + P QA T + P+ + +P + PP+GS A++ P
Sbjct: 734 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ----APNQPQ 789
Query: 231 LPPCP--------EDIAKEKRTPAPEPEPCEASELPAKRLRSS----EEPTEKEPPGQLQ 278
P P +R P+P P P + P + L S P+ +PP Q
Sbjct: 790 APTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ 849
Query: 279 VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQ 338
P + P P L P+ Q QA + + P T Q+
Sbjct: 850 GPPGPHSLQAGPLLQHPGPPQPFGLP--------PQASQGQAPLGTSPAAAYPHTSLQL- 900
Query: 339 PKLQKQAQTQTSPEHLVLQQKQV-QPQLQQEAEPQKQVQPQVQPQAHSQ-----GPRQVQ 392
P Q Q+Q P L + P ++ P + PQAH GP
Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPP--PTTPIPQLPAPQAHKHPPHLSGPSPFS 958
Query: 393 LQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQ 452
+ P ++P H PP LQ Q+Q P Q Q Q PP
Sbjct: 959 MNANLPPPPALKPLSSLSTH-HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017
Query: 453 VSVQPPEQTHEQPHTQP--QVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVG 510
S PP H+ P Q + P+ C P + G P G
Sbjct: 1018 AS-HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC----PSTSTPPAGPGTSAQPPCSG 1072
Query: 511 TQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVP 570
S I S+C L + + A L ++ P +P P
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEA-----------------LDDAEE------PESP-P 1108
Query: 571 RPSDSVSSTPAATSTPS--KQALQFFCYI 597
P S S P TPS Q+ +F+ ++
Sbjct: 1109 PPPRSPSPEPTVVDTPSHASQSARFYKHL 1137
Score = 50.4 bits (119), Expect = 7e-06
Identities = 94/452 (20%), Positives = 154/452 (34%), Gaps = 74/452 (16%)
Query: 163 PPVGVPMNPSQF----------NLSGRNPQKQARTSSSTTPNRKDSSSQ-------TMPV 205
PP+ P++P F LSG++ + R+ S + R Q T P+
Sbjct: 543 PPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPI 602
Query: 206 -EDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
ED S AA + + + + + + +E +P + +R +
Sbjct: 603 NEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNK--------RQREKV 654
Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
+ + E + + K Q +R P + + ++ + P+ + Q
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE--GSSDPKDID---QDNR 709
Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
T P IPS ++ + +S + +LQ + Q P P PQ
Sbjct: 710 STSPSIPSPQ-------DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762
Query: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQ 444
+ GP V PQ P A SQ P Q Q T P H Q P++
Sbjct: 763 TPGP--------TPSATAVPPQGSPTA-SQAPN------QPQAPTAPVPHTHIQQAPALH 807
Query: 445 PQE----HPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGG 500
PQ HPP S PP Q QP AP +H G P +++AG
Sbjct: 808 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPS----APSHAQPPLHGQG-PPGPHSLQAGPL 862
Query: 501 MEKT-LPEPVGTQVSMEEIQNESACGLD-VGECENRAREMPGVWGAGGSLKVTILQSSDS 558
++ P+P G + + Q ++ G + + ++P A LQS
Sbjct: 863 LQHPGPPQPFG--LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSA--------LQSQQP 912
Query: 559 RAFSTVPLTPVPRPSDSVSSTPAATSTPSKQA 590
+P P+ P T P+ QA
Sbjct: 913 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA 944
Score = 42.0 bits (97), Expect = 0.003
Identities = 92/432 (21%), Positives = 133/432 (30%), Gaps = 87/432 (20%)
Query: 46 PPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQR-------ALLLQQLQGLD 98
PP PL + + P Q PL SL G +LQ L Q QG
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 883
Query: 99 QF-AMPPATYDTAGLTMPTATLG----------NLRGYGMASPGLAAPSLTP-PQLATPN 146
P A Y L +P + L +A P + P TP PQL P
Sbjct: 884 PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ 943
Query: 147 LQQFFPQATRQS------LLGPPPVGVPM-----------NPSQFNLSGRNPQKQARTSS 189
+ P + S L PPP P+ +P L PQ Q SS
Sbjct: 944 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM---PQSQPLPSS 1000
Query: 190 STTPNRKDSSSQTMPVEDKSDPPEGSEEAAE----------------------PRMDTPE 227
P + SQ +P S PP G + A P TP
Sbjct: 1001 PAQPPGL-TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP 1059
Query: 228 ----DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 283
PPC A P ++ + L +EEP PP P
Sbjct: 1060 AGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--------P 1111
Query: 284 QARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQK 343
++ P TP A ++ + R A+ P S KL K
Sbjct: 1112 RSPSPEPTVVDTPS---HASQSARFYKHLDRGYNSCARTDLYFMPLAGS-------KLAK 1161
Query: 344 QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQV 403
+ + +QK + ++E E +K+ + + + + + R + A +
Sbjct: 1162 KREEAIEKAKREAEQKARE---EREREKEKEKEREREREREREAERAAKASSSAHEGRLS 1218
Query: 404 QPQVQPQAHSQP 415
PQ+ H +P
Sbjct: 1219 DPQLSGPGHMRP 1230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,137,994
Number of Sequences: 37866
Number of extensions: 2580995
Number of successful extensions: 49974
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 508
Number of HSP's successfully gapped in prelim test: 1100
Number of HSP's that attempted gapping in prelim test: 20551
Number of HSP's gapped (non-prelim): 14630
length of query: 898
length of database: 18,247,518
effective HSP length: 111
effective length of query: 787
effective length of database: 14,044,392
effective search space: 11052936504
effective search space used: 11052936504
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.