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Search of human proteins with 42518080
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42518080 transcription factor 7 (T-cell specific, HMG-box)
isoform 1 [Homo sapiens]
(384 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42518080 transcription factor 7 (T-cell specific, HMG-box) is... 792 0.0
gi|42518078 transcription factor 7 (T-cell specific, HMG-box) is... 562 e-160
gi|47419938 transcription factor 7 (T-cell specific, HMG-box) is... 562 e-160
gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6... 509 e-144
gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5... 509 e-144
gi|42518074 transcription factor 7 (T-cell specific, HMG-box) is... 509 e-144
gi|42714657 transcription factor 7 (T-cell specific, HMG-box) is... 509 e-144
gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo ... 325 5e-89
gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens] 304 8e-83
gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo ... 302 3e-82
gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens] 297 9e-81
gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo sa... 290 2e-78
gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens] 284 1e-76
gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens] 284 1e-76
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] 278 8e-75
gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens] 262 4e-70
gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens] 258 8e-69
gi|112421108 capicua homolog [Homo sapiens] 74 2e-13
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 65 8e-11
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 65 8e-11
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 65 8e-11
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 65 8e-11
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 60 4e-09
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 60 4e-09
gi|8924248 SRY-box 18 [Homo sapiens] 60 4e-09
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 58 1e-08
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 58 1e-08
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 58 1e-08
gi|41406089 SRY-box 13 [Homo sapiens] 57 2e-08
gi|11967991 SRY-box 17 [Homo sapiens] 56 5e-08
>gi|42518080 transcription factor 7 (T-cell specific, HMG-box)
isoform 1 [Homo sapiens]
Length = 384
Score = 792 bits (2046), Expect = 0.0
Identities = 384/384 (100%), Positives = 384/384 (100%)
Query: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESE 60
MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESE
Sbjct: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESE 60
Query: 61 GAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKET 120
GAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKET
Sbjct: 61 GAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKET 120
Query: 121 VYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAPADISQ 180
VYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAPADISQ
Sbjct: 121 VYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAPADISQ 180
Query: 181 KQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPAIVPPS 240
KQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPAIVPPS
Sbjct: 181 KQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPAIVPPS 240
Query: 241 GKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAIN 300
GKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAIN
Sbjct: 241 GKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAIN 300
Query: 301 QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGG 360
QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGG
Sbjct: 301 QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGG 360
Query: 361 KRNAFGTYPEKAAAPAPFLPMTVL 384
KRNAFGTYPEKAAAPAPFLPMTVL
Sbjct: 361 KRNAFGTYPEKAAAPAPFLPMTVL 384
>gi|42518078 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 562 bits (1449), Expect = e-160
Identities = 269/269 (100%), Positives = 269/269 (100%)
Query: 116 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 175
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 176 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 235
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 236 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 295
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 296 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 355
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 356 STTGGKRNAFGTYPEKAAAPAPFLPMTVL 384
STTGGKRNAFGTYPEKAAAPAPFLPMTVL
Sbjct: 241 STTGGKRNAFGTYPEKAAAPAPFLPMTVL 269
>gi|47419938 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 562 bits (1449), Expect = e-160
Identities = 269/269 (100%), Positives = 269/269 (100%)
Query: 116 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 175
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 176 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 235
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 236 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 295
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 296 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 355
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 356 STTGGKRNAFGTYPEKAAAPAPFLPMTVL 384
STTGGKRNAFGTYPEKAAAPAPFLPMTVL
Sbjct: 241 STTGGKRNAFGTYPEKAAAPAPFLPMTVL 269
>gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6
[Homo sapiens]
Length = 250
Score = 509 bits (1311), Expect = e-144
Identities = 243/243 (100%), Positives = 243/243 (100%)
Query: 116 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 175
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 176 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 235
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 236 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 295
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 296 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 355
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 356 STT 358
STT
Sbjct: 241 STT 243
>gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5
[Homo sapiens]
Length = 366
Score = 509 bits (1311), Expect = e-144
Identities = 243/243 (100%), Positives = 243/243 (100%)
Query: 116 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 175
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 176 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 235
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 236 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 295
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 296 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 355
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 356 STT 358
STT
Sbjct: 241 STT 243
>gi|42518074 transcription factor 7 (T-cell specific, HMG-box)
isoform 3 [Homo sapiens]
Length = 269
Score = 509 bits (1311), Expect = e-144
Identities = 243/243 (100%), Positives = 243/243 (100%)
Query: 116 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 175
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 176 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 235
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 236 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 295
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 296 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 355
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 356 STT 358
STT
Sbjct: 241 STT 243
>gi|42714657 transcription factor 7 (T-cell specific, HMG-box)
isoform 4 [Homo sapiens]
Length = 268
Score = 509 bits (1311), Expect = e-144
Identities = 243/243 (100%), Positives = 243/243 (100%)
Query: 116 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 175
MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP
Sbjct: 1 MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAP 60
Query: 176 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 235
ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA
Sbjct: 61 ADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPA 120
Query: 236 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 295
IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE
Sbjct: 121 IVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 296 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 355
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 356 STT 358
STT
Sbjct: 241 STT 243
>gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo
sapiens]
Length = 386
Score = 325 bits (832), Expect = 5e-89
Identities = 198/403 (49%), Positives = 245/403 (60%), Gaps = 42/403 (10%)
Query: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPER--DLAELKSSLVNE 58
MPQL GGGG GG +L A DE++ F+DEG+ Q +K + PE DLA++KSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 59 SEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYK 118
SE G E + +Q + DK E +DG K P+ G+Y
Sbjct: 61 SEIIPASNG--------------HEVARQAQTSQEPYHDKAREHPDDG-KHPD--GGLYN 103
Query: 119 E----TVYSAFNLL--MHYPPPSGAGQHPQPQP------PLHKANQPPHGVPQLSLY--E 164
+ + YS + ++ M+ P G P P P+ + + H + L Y E
Sbjct: 104 KGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDE 163
Query: 165 HFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGS 222
HF+ HP+ P+D++ KQ + R PD+ FY L+ G +GQ+ + WF+H +
Sbjct: 164 HFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMI---P 220
Query: 223 GVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFML 278
G PG H IPHPAIV P KQE D +L K Q E + E+E K+P IKKPLNAFML
Sbjct: 221 GPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFML 280
Query: 279 YMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA 338
YMKEMRA V+AECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA
Sbjct: 281 YMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA 340
Query: 339 RDNYGKKKRRSREKHQESTTGGKRNAFGTYPEKAAAPAPFLPM 381
RDNYGKKK+R REK QES +GGKR++F T KAA P P L M
Sbjct: 341 RDNYGKKKKRKREKLQESASGGKRSSFPTCKAKAATPGPLLEM 383
>gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]
Length = 442
Score = 304 bits (779), Expect = 8e-83
Identities = 203/461 (44%), Positives = 251/461 (54%), Gaps = 102/461 (22%)
Query: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESE 60
MPQL+ GGG DDLGA DEL++F+DEGE+++ S +S+A ERDLA++KSSLVNESE
Sbjct: 1 MPQLNGGGG-----DDLGANDELISFKDEGEQEEKSSENSSA--ERDLADVKSSLVNESE 53
Query: 61 GAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKET 120
+ ++EA R F DK E LE+ K + G++K
Sbjct: 54 -------------TNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQD--GGLFKGP 98
Query: 121 VYSAFNLLM------HYPP---------------------PSGAGQHPQ-------PQPP 146
Y + +M Y P +G+ Q Q P P
Sbjct: 99 PYPGYPFIMIPDLTSPYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPA 158
Query: 147 LHKANQPP--------HGVPQLSLY--EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSG 194
+N+ P H + L Y EHF +P P PAD+ K + RP PD+S
Sbjct: 159 HIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISP 218
Query: 195 FYSLTSGSMGQLPHTVSW----------------FTHP---SLMLGSGVPG--------- 226
+Y L+ G++GQ+PH + W F HP +L + + +
Sbjct: 219 YYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPH 278
Query: 227 ---HPAAIPHPAIVPPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYM 280
H IPHPAIV P+ KQE D + +SK E+E KKP IKKPLNAFMLYM
Sbjct: 279 HTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYM 338
Query: 281 KEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARD 340
KEMRAKV+AECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARD
Sbjct: 339 KEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARD 398
Query: 341 NYGKKKRRSREKHQESTTGGKRNAFGTYPEKAAAPAPFLPM 381
NYGKKK+R R+K T G K++AF TY KAAA A L M
Sbjct: 399 NYGKKKKRKRDKQPGETNGEKKSAFATYKVKAAASAHPLQM 439
>gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo
sapiens]
Length = 371
Score = 302 bits (774), Expect = 3e-82
Identities = 186/381 (48%), Positives = 231/381 (60%), Gaps = 42/381 (11%)
Query: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPER--DLAELKSSLVNE 58
MPQL GGGG GG +L A DE++ F+DEG+ Q +K + PE DLA++KSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 59 SEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYK 118
SE G E + +Q + DK E +DG K P+ G+Y
Sbjct: 61 SEIIPASNG--------------HEVARQAQTSQEPYHDKAREHPDDG-KHPD--GGLYN 103
Query: 119 E----TVYSAFNLL--MHYPPPSGAGQHPQPQP------PLHKANQPPHGVPQLSLY--E 164
+ + YS + ++ M+ P G P P P+ + + H + L Y E
Sbjct: 104 KGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDE 163
Query: 165 HFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGS 222
HF+ HP+ P+D++ KQ + R PD+ FY L+ G +GQ+ + WF+H +
Sbjct: 164 HFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMI---P 220
Query: 223 GVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFML 278
G PG H IPHPAIV P KQE D +L K Q E + E+E K+P IKKPLNAFML
Sbjct: 221 GPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFML 280
Query: 279 YMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA 338
YMKEMRA V+AECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA
Sbjct: 281 YMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA 340
Query: 339 RDNYGKKKRRSREKHQESTTG 359
RDNYGKKK+R REK QES +G
Sbjct: 341 RDNYGKKKKRKREKLQESASG 361
>gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens]
Length = 455
Score = 297 bits (761), Expect = 9e-81
Identities = 203/474 (42%), Positives = 249/474 (52%), Gaps = 115/474 (24%)
Query: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESE 60
MPQL+ GGG DDLGA DEL++F+DEGE+++ S +S+A ERDLA++KSSLVNESE
Sbjct: 1 MPQLNGGGG-----DDLGANDELISFKDEGEQEEKSSENSSA--ERDLADVKSSLVNESE 53
Query: 61 GAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKET 120
+ ++EA R F DK E LE+ K + G++K
Sbjct: 54 -------------TNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQD--GGLFKGP 98
Query: 121 VYSAFNLLM------HYPP---------------------PSGAGQHPQ-------PQPP 146
Y + +M Y P +G+ Q Q P P
Sbjct: 99 PYPGYPFIMIPDLTSPYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPA 158
Query: 147 LHKANQPP--------HGVPQLSLY--EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSG 194
+N+ P H + L Y EHF +P P PAD+ K + RP PD+S
Sbjct: 159 HIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISP 218
Query: 195 FYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHP-------------------------- 228
+Y L+ G++GQ+PH + W P + +G HP
Sbjct: 219 YYPLSPGTVGQIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLH 278
Query: 229 -AAIPHPAIVPPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMR 284
IPHPAIV P+ KQE D + +SK E+E KKP IKKPLNAFMLYMKEMR
Sbjct: 279 TTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMR 338
Query: 285 AKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGK 344
AKV+AECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGK
Sbjct: 339 AKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGK 398
Query: 345 KKRRSREKHQEST-----------------TGGKRNAFGTYPEKAAAPAPFLPM 381
KK+R R+K T TG K++AF TY KAAA A L M
Sbjct: 399 KKKRKRDKQPGETNEHSECFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQM 452
>gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo
sapiens]
Length = 399
Score = 290 bits (741), Expect = 2e-78
Identities = 185/406 (45%), Positives = 230/406 (56%), Gaps = 64/406 (15%)
Query: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPER--DLAELKSSLVNE 58
MPQL GGGG GG +L A DE++ F+DEG+ Q +K + PE DLA++KSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 59 SEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYK 118
SE G E + +Q + DK E +DG K P+ G+Y
Sbjct: 61 SEIIPASNG--------------HEVARQAQTSQEPYHDKAREHPDDG-KHPD--GGLYN 103
Query: 119 E----TVYSAFNLL--MHYPPPSGAGQHPQPQP------PLHKANQPPHGVPQLSLY--E 164
+ + YS + ++ M+ P G P P P+ + + H + L Y E
Sbjct: 104 KGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDE 163
Query: 165 HFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGS 222
HF+ HP+ P+D++ KQ + R PD+ FY L+ G +GQ+ + W P +
Sbjct: 164 HFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITG 223
Query: 223 G----------------------VPG----HPAAIPHPAIVPPSGKQELQPFDRNL---K 253
G +PG H IPHPAIV P KQE D +L K
Sbjct: 224 GFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVK 283
Query: 254 TQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSRE 313
Q E + E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKESAAINQILGRRWHALSRE
Sbjct: 284 PQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSRE 343
Query: 314 EQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTG 359
EQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R REK QES +G
Sbjct: 344 EQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASG 389
>gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]
Length = 596
Score = 284 bits (726), Expect = 1e-76
Identities = 190/437 (43%), Positives = 236/437 (54%), Gaps = 102/437 (23%)
Query: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESE 60
MPQL+ GGG DDLGA DEL++F+DEGE+++ S +S+A ERDLA++KSSLVNESE
Sbjct: 1 MPQLNGGGG-----DDLGANDELISFKDEGEQEEKSSENSSA--ERDLADVKSSLVNESE 53
Query: 61 GAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKET 120
+ ++EA R F DK E LE+ K + G++K
Sbjct: 54 -------------TNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQD--GGLFKGP 98
Query: 121 VYSAFNLLM------HYPP---------------------PSGAGQHPQ-------PQPP 146
Y + +M Y P +G+ Q Q P P
Sbjct: 99 PYPGYPFIMIPDLTSPYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPA 158
Query: 147 LHKANQPP--------HGVPQLSLY--EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSG 194
+N+ P H + L Y EHF +P P PAD+ K + RP PD+S
Sbjct: 159 HIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISP 218
Query: 195 FYSLTSGSMGQLPHTVSW----------------FTHP---SLMLGSGVPG--------- 226
+Y L+ G++GQ+PH + W F HP +L + + +
Sbjct: 219 YYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPH 278
Query: 227 ---HPAAIPHPAIVPPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYM 280
H IPHPAIV P+ KQE D + +SK E+E KKP IKKPLNAFMLYM
Sbjct: 279 HTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYM 338
Query: 281 KEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARD 340
KEMRAKV+AECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARD
Sbjct: 339 KEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARD 398
Query: 341 NYGKKKRRSREKHQEST 357
NYGKKK+R R+K T
Sbjct: 399 NYGKKKKRKRDKQPGET 415
>gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]
Length = 579
Score = 284 bits (726), Expect = 1e-76
Identities = 190/437 (43%), Positives = 236/437 (54%), Gaps = 102/437 (23%)
Query: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESE 60
MPQL+ GGG DDLGA DEL++F+DEGE+++ S +S+A ERDLA++KSSLVNESE
Sbjct: 1 MPQLNGGGG-----DDLGANDELISFKDEGEQEEKSSENSSA--ERDLADVKSSLVNESE 53
Query: 61 GAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKET 120
+ ++EA R F DK E LE+ K + G++K
Sbjct: 54 -------------TNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQD--GGLFKGP 98
Query: 121 VYSAFNLLM------HYPP---------------------PSGAGQHPQ-------PQPP 146
Y + +M Y P +G+ Q Q P P
Sbjct: 99 PYPGYPFIMIPDLTSPYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPA 158
Query: 147 LHKANQPP--------HGVPQLSLY--EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSG 194
+N+ P H + L Y EHF +P P PAD+ K + RP PD+S
Sbjct: 159 HIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISP 218
Query: 195 FYSLTSGSMGQLPHTVSW----------------FTHP---SLMLGSGVPG--------- 226
+Y L+ G++GQ+PH + W F HP +L + + +
Sbjct: 219 YYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPH 278
Query: 227 ---HPAAIPHPAIVPPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYM 280
H IPHPAIV P+ KQE D + +SK E+E KKP IKKPLNAFMLYM
Sbjct: 279 HTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYM 338
Query: 281 KEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARD 340
KEMRAKV+AECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARD
Sbjct: 339 KEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARD 398
Query: 341 NYGKKKRRSREKHQEST 357
NYGKKK+R R+K T
Sbjct: 399 NYGKKKKRKRDKQPGET 415
>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
Length = 602
Score = 278 bits (710), Expect = 8e-75
Identities = 189/445 (42%), Positives = 241/445 (54%), Gaps = 95/445 (21%)
Query: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESE 60
MPQL+ GGG DDLGA DEL++F+DEGE+++ S +S+A ERDLA++KSSLVNESE
Sbjct: 1 MPQLNGGGG-----DDLGANDELISFKDEGEQEEKSSENSSA--ERDLADVKSSLVNESE 53
Query: 61 ---GAAGGAGIPGVPGAGAGARGEAEALGREHAAQR-----------------LFPDKLP 100
++ + P + + + E AA+R + PD
Sbjct: 54 TNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTS 113
Query: 101 EPLEDGLKAPECTSGMYKE--TVYSAFNLLMHY-------------PPPSGAGQHPQ--- 142
L +G +P + ++ T YSA+ + H +G+ Q Q
Sbjct: 114 PYLPNGSLSPTARTLHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQSRQALK 173
Query: 143 ----PQPPLHKANQPP--------HGVPQLSLY--EHFNSPHPTP-APADISQKQ-VHRP 186
P P +N+ P H + L Y EHF +P P PAD+ K + RP
Sbjct: 174 DARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRP 233
Query: 187 LQTPDLSGFYSLTSGSMGQLPHTVSW----------------FTHP---SLMLGSGVPG- 226
PD+S +Y L+ G++GQ+PH + W F HP +L + + +
Sbjct: 234 PHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRF 293
Query: 227 -----------HPAAIPHPAIVPPSGKQELQPFD---RNLKTQAESKAEKEAKKPTIKKP 272
H IPHPAIV P+ KQE D + +SK E+E KKP IKKP
Sbjct: 294 PPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKP 353
Query: 273 LNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQL 332
LNAFMLYMKEMRAKV+AECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQL
Sbjct: 354 LNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQL 413
Query: 333 YPGWSARDNYGKKKRRSREKHQEST 357
YPGWSARDNYGKKK+R R+K T
Sbjct: 414 YPGWSARDNYGKKKKRKRDKQPGET 438
>gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]
Length = 588
Score = 262 bits (669), Expect = 4e-70
Identities = 189/479 (39%), Positives = 241/479 (50%), Gaps = 118/479 (24%)
Query: 1 MPQLDSGGGG---------------AGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPE 45
MPQL GGGG AGGGDDLGA DEL+ FQDEG E+ + S DSA+ +
Sbjct: 1 MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSASA-Q 59
Query: 46 RDLAELKSSLVNESEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLED 105
RDL E+KSSLVNESE + + ++EA R + F + P
Sbjct: 60 RDLDEVKSSLVNESENQSSSS--------------DSEAERRPQPVRDTF--QKPRDYFA 103
Query: 106 GLKAPECTSGMYKETVYSAFNLLM-------------------------HYP----PPSG 136
++ P+ S +K Y + LM +P P S
Sbjct: 104 EVRRPQ-DSAFFKGPPYPGYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSA 162
Query: 137 AGQHPQPQPPLHKANQPP--------HGVPQLSLY--EHFN--SPHPTPAPADISQKQ-V 183
+ + P H +N+ P H + L Y +HF+ SP PT +I K +
Sbjct: 163 TVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSP-PTHLSPEIDPKTGI 221
Query: 184 HRPLQTPDLSGFYSLTSGSMGQLPHTVSWFT------------------HPSLMLGSGV- 224
RP +LS +Y L+ G++GQ+PH + W +P+L + + +
Sbjct: 222 PRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMS 281
Query: 225 -------------PGHP----AAIPHPAIVPPSGKQELQPFDRNLKTQAESKA---EKEA 264
P HP + IPHPAIV P KQE P + +S ++E
Sbjct: 282 SLVSSRFSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEE 341
Query: 265 KKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARK 324
KKP +KKPLNAFMLYMKEMRAKV+AECTLKESAAINQILGR+WH LSREEQAKYYELARK
Sbjct: 342 KKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARK 401
Query: 325 ERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGK--RNAFGTYPEKAAAP-APFLP 380
ERQLH QLYP WSARDNYGKKK+R REK T + + A G K+ P +LP
Sbjct: 402 ERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQVQEAEGALASKSKKPCVQYLP 460
>gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens]
Length = 489
Score = 258 bits (658), Expect = 8e-69
Identities = 192/501 (38%), Positives = 232/501 (46%), Gaps = 135/501 (26%)
Query: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQD---------------------------EGEEQ 33
MPQL+ GGG DDLGA DEL++F+D E E
Sbjct: 1 MPQLNGGGG-----DDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETN 55
Query: 34 DDKSRDSAAGP----------ERDLAELKSSLVNESEGAAGGAGIPGVP----------- 72
+ S DS A ++ L+ + + G G PG P
Sbjct: 56 QNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPY 115
Query: 73 ----GAGAGARGEAEA--------LGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKET 120
AR + G + Q L + P P P CT G
Sbjct: 116 LPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSPLPCCTQG----- 170
Query: 121 VYSAFNLLMHYPPPSGAGQHPQP------QPPLHKANQP-------------PHGVPQLS 161
+ H+ PPS Q L K +P PH V L+
Sbjct: 171 -----HDCQHFYPPSDFTVSTQVFRDMKRSHSLQKVGEPWCIESNKVPVVQHPHHVHPLT 225
Query: 162 LY-----EHFNSPHPTP-APADISQKQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSW-- 212
EHF +P P PAD+ K + RP PD+S +Y L+ G++GQ+PH + W
Sbjct: 226 PLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLV 285
Query: 213 --------------FTHP---SLMLGSGVPG------------HPAAIPHPAIVPPSGKQ 243
F HP +L + + + H IPHPAIV P+ KQ
Sbjct: 286 PQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQ 345
Query: 244 ELQPFD---RNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAIN 300
E D + +SK E+E KKP IKKPLNAFMLYMKEMRAKV+AECTLKESAAIN
Sbjct: 346 ESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 405
Query: 301 QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGG 360
QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R R+K T G
Sbjct: 406 QILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNGE 465
Query: 361 KRNAFGTYPEKAAAPAPFLPM 381
K++AF TY KAAA A L M
Sbjct: 466 KKSAFATYKVKAAASAHPLQM 486
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 74.3 bits (181), Expect = 2e-13
Identities = 71/291 (24%), Positives = 119/291 (40%), Gaps = 39/291 (13%)
Query: 96 PDKLPEPLEDGLKAPE-CTSGMYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPP 154
PD +P E A S KE SA + H PP G G +PP + P
Sbjct: 49 PDPSVQPSEAQQPASHPVASNQSKEPAESA--AVAHERPPGGTGSADPERPPGATCPESP 106
Query: 155 HGVPQ--LSLYEHFNSPHPTPAPADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSW 212
P L + E P PT ++++ P P L S + H ++
Sbjct: 107 GPGPPHPLGVVESGKGPPPT------TEEEASGPPGEPRLD--------SETESDHDDAF 152
Query: 213 FTHPSLMLGSGVPGHPAAIPHPAIVPPSGKQELQ-----PFDRNLKTQAESKAEKEAKKP 267
+ S P + P GK+ Q P +R+ ++ + ++ + +K
Sbjct: 153 LSIMS--------------PEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKD 198
Query: 268 TIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 327
I++P+NAFM++ K RA V +++ +++ILG W+AL +E+ KY++LA + ++
Sbjct: 199 HIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKE 258
Query: 328 LHMQLYPGWSARDNYGKKKRRSREKHQESTTGG-KRNAFGTYPEKAAAPAP 377
H + +P W + KK + GG K + E A AP
Sbjct: 259 AHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAAAP 309
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 65.5 bits (158), Expect = 8e-11
Identities = 38/122 (31%), Positives = 66/122 (54%), Gaps = 15/122 (12%)
Query: 254 TQAESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWH 308
T AE++ ++A+ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW
Sbjct: 614 TVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK 673
Query: 309 ALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGKRNAFGTY 368
++S +E+ YYE + ++H++ YP NY K R R GK+ G Y
Sbjct: 674 SMSNQEKQPYYEEQARLSKIHLEKYP------NYKYKPRPKR----TCIVDGKKLRIGEY 723
Query: 369 PE 370
+
Sbjct: 724 KQ 725
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 65.5 bits (158), Expect = 8e-11
Identities = 38/122 (31%), Positives = 66/122 (54%), Gaps = 15/122 (12%)
Query: 254 TQAESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWH 308
T AE++ ++A+ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW
Sbjct: 574 TVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK 633
Query: 309 ALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGKRNAFGTY 368
++S +E+ YYE + ++H++ YP NY K R R GK+ G Y
Sbjct: 634 SMSNQEKQPYYEEQARLSKIHLEKYP------NYKYKPRPKR----TCIVDGKKLRIGEY 683
Query: 369 PE 370
+
Sbjct: 684 KQ 685
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 65.5 bits (158), Expect = 8e-11
Identities = 38/122 (31%), Positives = 66/122 (54%), Gaps = 15/122 (12%)
Query: 254 TQAESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWH 308
T AE++ ++A+ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW
Sbjct: 577 TVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK 636
Query: 309 ALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGKRNAFGTY 368
++S +E+ YYE + ++H++ YP NY K R R GK+ G Y
Sbjct: 637 SMSNQEKQPYYEEQARLSKIHLEKYP------NYKYKPRPKR----TCIVDGKKLRIGEY 686
Query: 369 PE 370
+
Sbjct: 687 KQ 688
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 65.5 bits (158), Expect = 8e-11
Identities = 38/122 (31%), Positives = 66/122 (54%), Gaps = 15/122 (12%)
Query: 254 TQAESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWH 308
T AE++ ++A+ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW
Sbjct: 581 TVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK 640
Query: 309 ALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGKRNAFGTY 368
++S +E+ YYE + ++H++ YP NY K R R GK+ G Y
Sbjct: 641 SMSNQEKQPYYEEQARLSKIHLEKYP------NYKYKPRPKR----TCIVDGKKLRIGEY 690
Query: 369 PE 370
+
Sbjct: 691 KQ 692
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 59.7 bits (143), Expect = 4e-09
Identities = 38/131 (29%), Positives = 64/131 (48%), Gaps = 11/131 (8%)
Query: 224 VPGHPAAIPHPAIVPPSGKQELQ-------PFDRNLKTQAESKAEKEAKKPTIKKPLNAF 276
VP P +++ PS K E + P D + SK + +K+P+NAF
Sbjct: 289 VPLTPVPTKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKD----RNGHVKRPMNAF 344
Query: 277 MLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGW 336
M++ + R + +A I+ LG W+ LS E++ YY+ A+K ++ H + +PGW
Sbjct: 345 MVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGW 404
Query: 337 SARDNYGKKKR 347
+ GK+KR
Sbjct: 405 VYQPRPGKRKR 415
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 59.7 bits (143), Expect = 4e-09
Identities = 38/131 (29%), Positives = 64/131 (48%), Gaps = 11/131 (8%)
Query: 224 VPGHPAAIPHPAIVPPSGKQELQ-------PFDRNLKTQAESKAEKEAKKPTIKKPLNAF 276
VP P +++ PS K E + P D + SK + +K+P+NAF
Sbjct: 289 VPLTPVPTKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKD----RNGHVKRPMNAF 344
Query: 277 MLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGW 336
M++ + R + +A I+ LG W+ LS E++ YY+ A+K ++ H + +PGW
Sbjct: 345 MVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGW 404
Query: 337 SARDNYGKKKR 347
+ GK+KR
Sbjct: 405 VYQPRPGKRKR 415
>gi|8924248 SRY-box 18 [Homo sapiens]
Length = 384
Score = 59.7 bits (143), Expect = 4e-09
Identities = 37/130 (28%), Positives = 68/130 (52%), Gaps = 12/130 (9%)
Query: 225 PGHPAAIPHPAIVPPS----GKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYM 280
P PA+ P P PP G+ L P R E +A E++ I++P+NAFM++
Sbjct: 45 PAAPASPPSPQRSPPRSPEPGRYGLSPAGRG-----ERQAADESR---IRRPMNAFMVWA 96
Query: 281 KEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARD 340
K+ R ++ + +A ++++LG+ W L+ E+ + E A + R H++ +P + R
Sbjct: 97 KDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRP 156
Query: 341 NYGKKKRRSR 350
K+ R++R
Sbjct: 157 RRKKQARKAR 166
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 58.2 bits (139), Expect = 1e-08
Identities = 28/86 (32%), Positives = 53/86 (61%), Gaps = 5/86 (5%)
Query: 256 AESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHAL 310
+ES+ +E++ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW A+
Sbjct: 152 SESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAM 211
Query: 311 SREEQAKYYELARKERQLHMQLYPGW 336
+ E+ YYE + + H++ YP +
Sbjct: 212 TNLEKQPYYEEQARLSKQHLEKYPDY 237
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 58.2 bits (139), Expect = 1e-08
Identities = 28/86 (32%), Positives = 53/86 (61%), Gaps = 5/86 (5%)
Query: 256 AESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHAL 310
+ES+ +E++ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW A+
Sbjct: 525 SESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAM 584
Query: 311 SREEQAKYYELARKERQLHMQLYPGW 336
+ E+ YYE + + H++ YP +
Sbjct: 585 TNLEKQPYYEEQARLSKQHLEKYPDY 610
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 58.2 bits (139), Expect = 1e-08
Identities = 28/86 (32%), Positives = 53/86 (61%), Gaps = 5/86 (5%)
Query: 256 AESKAEKEAK-----KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHAL 310
+ES+ +E++ +P IK+P+NAFM++ K+ R K++ ++ I++ILG RW A+
Sbjct: 538 SESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAM 597
Query: 311 SREEQAKYYELARKERQLHMQLYPGW 336
+ E+ YYE + + H++ YP +
Sbjct: 598 TNLEKQPYYEEQARLSKQHLEKYPDY 623
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 57.4 bits (137), Expect = 2e-08
Identities = 33/100 (33%), Positives = 55/100 (55%), Gaps = 10/100 (10%)
Query: 269 IKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQL 328
IK+P+NAFM++ K+ R K++ +++I++ILG RW +++ +E+ YYE + +
Sbjct: 424 IKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQ 483
Query: 329 HMQLYPGWSARDNYGKKKRRSREKHQESTTGGKRNAFGTY 368
H++ YP +Y K R R E GKR G Y
Sbjct: 484 HLEKYP------DYKYKPRPKRTCIVE----GKRLRVGEY 513
>gi|11967991 SRY-box 17 [Homo sapiens]
Length = 414
Score = 56.2 bits (134), Expect = 5e-08
Identities = 44/165 (26%), Positives = 81/165 (49%), Gaps = 19/165 (11%)
Query: 216 PSLMLGSGVPGHPAAIPHPAIVPPSGKQELQ---PFDRNLKTQAESKAEKEAKKPTIKKP 272
P++M G G P + P G +++ P + A +A+ E++ I++P
Sbjct: 21 PAVMAGLG------PCPWAESLSPIGDMKVKGEAPANSGAPAGAAGRAKGESR---IRRP 71
Query: 273 LNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQL 332
+NAFM++ K+ R ++ + +A ++++LG+ W AL+ E+ + E A + R HMQ
Sbjct: 72 MNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQD 131
Query: 333 YPGWSARDNYGKKKRRSREKHQESTTGGKRNAFGTYPEKAAAPAP 377
+P + R +RR + K + GG + G +AAA P
Sbjct: 132 HPNYKYR-----PRRRKQVKRLKRVEGGFLH--GLAEPQAAALGP 169
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,340,886
Number of Sequences: 37866
Number of extensions: 1201602
Number of successful extensions: 9028
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 427
Number of HSP's that attempted gapping in prelim test: 7048
Number of HSP's gapped (non-prelim): 2281
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.