Guide to the Human Genome
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Name: TCF7 Sequence: fasta or formatted (384aa) NCBI GI: 42518080
Description:

transcription factor 7 (T-cell specific, HMG-box) isoform 1

Referenced in:

SOX Family
T cells

Other entries for this name:
alt prot [366aa] transcription factor 7 (T-cell specific, HMG-box) 5
alt prot [250aa] transcription factor 7 (T-cell specific, HMG-box) 6
alt prot [269aa] transcription factor 7 (T-cell specific, HMG-box) isoform 3
alt prot [269aa] transcription factor 7 (T-cell specific, HMG-box) isoform 2
alt prot [268aa] transcription factor 7 (T-cell specific, HMG-box) isoform 4
alt prot [269aa] transcription factor 7 (T-cell specific, HMG-box) isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.9         42           3
 C cysteine            0.5          2           1
 D aspartate           3.9         15           2
 E glutamate           7.8         30           2
 F phenylalanine       2.6         10           1
 G glycine             9.9         38           4
 H histidine           3.9         15           1
 I isoleucine          2.1          8           1
 K lysine              6.8         26           3
 L leucine             9.1         35           2
 M methionine          2.6         10           1
 N asparagine          2.3          9           1
 P proline            10.7         41           3
 Q glutamine           5.5         21           1
 R arginine            4.7         18           2
 S serine              6.8         26           2
 T threonine           3.6         14           2
 V valine              2.6         10           1
 W tryptophan          0.8          3           1
 Y tyrosine            2.9         11           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transcription factor 7 (T-cell specific, HMG-box) is... 
TCF7                  0.700   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.700   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.631   transcription factor 7 (T-cell specific, HMG-box) 6...
TCF7                  0.631   transcription factor 7 (T-cell specific, HMG-box) 5...
TCF7                  0.631   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.631   transcription factor 7 (T-cell specific, HMG-box) is...
LEF1                  0.391   lymphoid enhancer-binding factor 1 isoform 3 
TCF7L2                0.364   transcription factor 7-like 2 isoform 6 
LEF1                  0.361   lymphoid enhancer-binding factor 1 isoform 2 
TCF7L2                0.355   transcription factor 7-like 2 isoform 4 
LEF1                  0.346   lymphoid enhancer-binding factor 1 isoform 1 
TCF7L2                0.338   transcription factor 7-like 2 isoform 2 
TCF7L2                0.338   transcription factor 7-like 2 isoform 5 
TCF7L2                0.330   transcription factor 7-like 2 isoform 1 
TCF7L1                0.309   HMG-box transcription factor TCF-3 
TCF7L2                0.304   transcription factor 7-like 2 isoform 3 
CIC                   0.064   capicua homolog 
SOX6                  0.052   SRY (sex determining region Y)-box 6 isoform 4 [Hom...
SOX6                  0.052   SRY (sex determining region Y)-box 6 isoform 3 [Hom...
SOX6                  0.052   SRY (sex determining region Y)-box 6 isoform 1 [Homo...
SOX6                  0.052   SRY (sex determining region Y)-box 6 isoform 2 [Homo...
SOX30                 0.046   SRY (sex determining region Y)-box 30 isoform b [Homo...
SOX30                 0.046   SRY (sex determining region Y)-box 30 isoform a [Hom...
SOX18                 0.046   SRY-box 18 
SOX5                  0.043   SRY (sex determining region Y)-box 5 isoform c [Homo...
SOX5                  0.043   SRY (sex determining region Y)-box 5 isoform b [Homo...
SOX5                  0.043   SRY (sex determining region Y)-box 5 isoform a [Homo...
SOX13                 0.042   SRY-box 13 
SOX17                 0.040   SRY-box 17 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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