Guide to the Human Genome
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Name: TCF7L2 Sequence: fasta or formatted (455aa) NCBI GI: 226371623
Description:

transcription factor 7-like 2 isoform 4

Referenced in:

SOX Family
T cells

Other entries for this name:
alt prot [596aa] transcription factor 7-like 2 isoform 2
alt prot [489aa] transcription factor 7-like 2 isoform 3
alt prot [579aa] transcription factor 7-like 2 isoform 5
alt prot [442aa] transcription factor 7-like 2 isoform 6
alt prot [602aa] transcription factor 7-like 2 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.8         31           3
 C cysteine            0.7          3           1
 D aspartate           4.2         19           2
 E glutamate           7.0         32           3
 F phenylalanine       2.2         10           1
 G glycine             5.9         27           4
 H histidine           4.8         22           2
 I isoleucine          3.3         15           1
 K lysine              7.5         34           4
 L leucine             7.7         35           2
 M methionine          2.2         10           1
 N asparagine          3.5         16           1
 P proline            11.9         54           3
 Q glutamine           4.6         21           1
 R arginine            4.8         22           2
 S serine              9.5         43           3
 T threonine           4.8         22           2
 V valine              4.2         19           2
 W tryptophan          0.9          4           1
 Y tyrosine            3.5         16           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transcription factor 7-like 2 isoform 4 
TCF7L2                0.941   transcription factor 7-like 2 isoform 6 
TCF7L2                0.939   transcription factor 7-like 2 isoform 2 
TCF7L2                0.917   transcription factor 7-like 2 isoform 3 
TCF7L2                0.900   transcription factor 7-like 2 isoform 5 
TCF7L2                0.885   transcription factor 7-like 2 isoform 1 
TCF7L1                0.609   HMG-box transcription factor TCF-3 
LEF1                  0.468   lymphoid enhancer-binding factor 1 isoform 1 
LEF1                  0.415   lymphoid enhancer-binding factor 1 isoform 3 
LEF1                  0.405   lymphoid enhancer-binding factor 1 isoform 2 
TCF7                  0.295   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.237   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.237   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.227   transcription factor 7 (T-cell specific, HMG-box) 6...
TCF7                  0.227   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.226   transcription factor 7 (T-cell specific, HMG-box) 5...
TCF7                  0.226   transcription factor 7 (T-cell specific, HMG-box) is...
CIC                   0.053   capicua homolog 
SOX30                 0.049   SRY (sex determining region Y)-box 30 isoform b [Homo...
SOX30                 0.049   SRY (sex determining region Y)-box 30 isoform a [Hom...
SOX6                  0.045   SRY (sex determining region Y)-box 6 isoform 4 [Hom...
SOX6                  0.045   SRY (sex determining region Y)-box 6 isoform 3 [Hom...
SOX6                  0.045   SRY (sex determining region Y)-box 6 isoform 1 [Homo...
SOX6                  0.045   SRY (sex determining region Y)-box 6 isoform 2 [Homo...
SOX13                 0.043   SRY-box 13 
SOX5                  0.039   SRY (sex determining region Y)-box 5 isoform c [Homo...
SOX5                  0.039   SRY (sex determining region Y)-box 5 isoform b [Homo...
SOX5                  0.039   SRY (sex determining region Y)-box 5 isoform a [Homo...
SOX8                  0.037   SRY (sex determining region Y)-box 8 
SOX14                 0.037   SRY-box 14 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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