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Search of human proteins with 39930469
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39930469 brix domain containing 1 [Homo sapiens]
(306 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39930469 brix domain containing 1 [Homo sapiens] 614 e-176
gi|55770900 BRIX [Homo sapiens] 48 9e-06
gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens] 33 0.32
gi|71896723 ceramide kinase-like isoform b [Homo sapiens] 32 0.92
gi|41680688 ceramide kinase-like isoform a [Homo sapiens] 32 0.92
gi|226442751 hypothetical protein LOC647309 [Homo sapiens] 31 1.2
gi|38788260 bromodomain PHD finger transcription factor isoform ... 30 2.0
gi|38788274 bromodomain PHD finger transcription factor isoform ... 30 2.0
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] 30 3.5
gi|110825982 hect domain and RLD 5 [Homo sapiens] 30 3.5
gi|83776600 aurora kinase B [Homo sapiens] 29 4.6
gi|237681069 spatacsin isoform 2 [Homo sapiens] 29 4.6
gi|93204888 spatacsin isoform 1 [Homo sapiens] 29 4.6
gi|27883882 P18SRP protein [Homo sapiens] 29 4.6
gi|166706917 hypothetical protein LOC199920 [Homo sapiens] 29 4.6
gi|154800469 lung cancer-related protein 8 isoform c [Homo sapiens] 29 6.0
gi|154800467 lung cancer-related protein 8 isoform b [Homo sapiens] 29 6.0
gi|21361664 lung cancer-related protein 8 isoform a [Homo sapiens] 29 6.0
gi|221219020 NYD-SP11 protein [Homo sapiens] 28 7.8
gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens] 28 7.8
gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens] 28 7.8
>gi|39930469 brix domain containing 1 [Homo sapiens]
Length = 306
Score = 614 bits (1583), Expect = e-176
Identities = 306/306 (100%), Positives = 306/306 (100%)
Query: 1 MDTLDRVVKPKTKRAKRFLEKREPKLNENIKNAMLIKGGNANATVTKVLKDVYALKKPYG 60
MDTLDRVVKPKTKRAKRFLEKREPKLNENIKNAMLIKGGNANATVTKVLKDVYALKKPYG
Sbjct: 1 MDTLDRVVKPKTKRAKRFLEKREPKLNENIKNAMLIKGGNANATVTKVLKDVYALKKPYG 60
Query: 61 VLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELG 120
VLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELG
Sbjct: 61 VLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELG 120
Query: 121 IENFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLAGL 180
IENFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLAGL
Sbjct: 121 IENFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLAGL 180
Query: 181 EYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSM 240
EYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSM
Sbjct: 181 EYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSM 240
Query: 241 KMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDHEKKS 300
KMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDHEKKS
Sbjct: 241 KMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDHEKKS 300
Query: 301 KRIKKN 306
KRIKKN
Sbjct: 301 KRIKKN 306
>gi|55770900 BRIX [Homo sapiens]
Length = 353
Score = 48.1 bits (113), Expect = 9e-06
Identities = 44/168 (26%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query: 121 IENFVSLKDIK-NSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLAG 179
++N +L ++K C +G++P+L F FD Y LK LLI F P
Sbjct: 143 VQNIHTLAELKMTGNCLKGSRPLLSF-DPAFDELPHYALLKELLIQIFSTPRYHPKSQPF 201
Query: 180 LEYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLAS---DDLY 236
+++V FT L+ +I+FR+++++ + + L E+GP L L + S LY
Sbjct: 202 VDHVFTFTILDNRIWFRNFQIIEEDAA-------LVEIGPRFVLNLIKIFQGSFGGPTLY 254
Query: 237 KLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGL 284
+ P P + + Y R Q +D+ KL+ ++ K L
Sbjct: 255 ----ENPHYQSPNMHRRVIRSITAAKY-REKQQVKDVQKLRKKEPKTL 297
>gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]
Length = 2608
Score = 33.1 bits (74), Expect = 0.32
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 22/124 (17%)
Query: 141 PMLIFAGDDFDVTEDYRRLKSLLIDFFRGPT----VSNIRLAGLEYVLHFTALNGKIYFR 196
P + G D ED L S++++F G T VSN+RL ++ + T
Sbjct: 1963 PGNVVRGASGDEDED---LDSVVVEFDDGDTGHIAVSNVRLLPPDFKIQCTE-------P 2012
Query: 197 SYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISH 256
S LL+ S RT ++ E PS A+ L + P+ALK KK+IS
Sbjct: 2013 SPALLVSSSCRRTKKVSSEAPPPS--------EAATPSLSPKAQDGPEALKTPGKKSISK 2064
Query: 257 DTFG 260
D G
Sbjct: 2065 DKAG 2068
>gi|71896723 ceramide kinase-like isoform b [Homo sapiens]
Length = 558
Score = 31.6 bits (70), Expect = 0.92
Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 7/106 (6%)
Query: 119 LGIENFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLA 178
LGI F+ LK +N K T ++ + D D+ +R+ K +L F P I L
Sbjct: 118 LGITLFICLKKEQN-KLKNSTLDLINLSEDHCDIW--FRQFKKILAGFPNRPKSLKILLN 174
Query: 179 GLEYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLV 224
+ T ++Y+ + LLK +G +T +E G +L L+
Sbjct: 175 PQSHKKEAT----QVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLL 216
>gi|41680688 ceramide kinase-like isoform a [Homo sapiens]
Length = 532
Score = 31.6 bits (70), Expect = 0.92
Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 7/106 (6%)
Query: 119 LGIENFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLA 178
LGI F+ LK +N K T ++ + D D+ +R+ K +L F P I L
Sbjct: 118 LGITLFICLKKEQN-KLKNSTLDLINLSEDHCDIW--FRQFKKILAGFPNRPKSLKILLN 174
Query: 179 GLEYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLV 224
+ T ++Y+ + LLK +G +T +E G +L L+
Sbjct: 175 PQSHKKEAT----QVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLL 216
>gi|226442751 hypothetical protein LOC647309 [Homo sapiens]
Length = 334
Score = 31.2 bits (69), Expect = 1.2
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 12/79 (15%)
Query: 225 LRRTHLASDDLYK-LSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKG 283
L R H ++ L + L+ + K L+ K KK +S D F YG+ K RK K
Sbjct: 101 LARLHEENNHLRQYLNSALVKCLEEKAKKLLSSDEFSKAYGKFRKGK--------RKSKE 152
Query: 284 LKKRPAERITEDHEKKSKR 302
+ PAE H K +KR
Sbjct: 153 QRYSPAE---IPHPKNAKR 168
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 30.4 bits (67), Expect = 2.0
Identities = 15/85 (17%), Positives = 46/85 (54%)
Query: 222 DLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKM 281
D++++ ++ + + ++ + + L+P K + +S ++ G R+ ++ + + + +
Sbjct: 1431 DMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQ 1490
Query: 282 KGLKKRPAERITEDHEKKSKRIKKN 306
K L++RP + ++ + K+ KKN
Sbjct: 1491 KKLEERPVNKCSDQIKLKNTTDKKN 1515
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 30.4 bits (67), Expect = 2.0
Identities = 15/85 (17%), Positives = 46/85 (54%)
Query: 222 DLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKM 281
D++++ ++ + + ++ + + L+P K + +S ++ G R+ ++ + + + +
Sbjct: 1305 DMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQ 1364
Query: 282 KGLKKRPAERITEDHEKKSKRIKKN 306
K L++RP + ++ + K+ KKN
Sbjct: 1365 KKLEERPVNKCSDQIKLKNTTDKKN 1389
>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 170
Score = 29.6 bits (65), Expect = 3.5
Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 15/90 (16%)
Query: 216 EMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSK 275
+ GPSL L L + K K K K KKKK +K+ K
Sbjct: 87 DAGPSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKK---------------KKKKKKK 131
Query: 276 LQTRKMKGLKKRPAERITEDHEKKSKRIKK 305
+ +K K +KR +R + +K+ K+ KK
Sbjct: 132 KKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161
>gi|110825982 hect domain and RLD 5 [Homo sapiens]
Length = 1024
Score = 29.6 bits (65), Expect = 3.5
Identities = 16/48 (33%), Positives = 24/48 (50%)
Query: 192 KIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLS 239
KI + +K L+ + R + P+ DL +RR HL D L +LS
Sbjct: 652 KIESKKHKAYLRSAAIEEERESEFALRPTFDLTVRRNHLIEDVLNQLS 699
>gi|83776600 aurora kinase B [Homo sapiens]
Length = 344
Score = 29.3 bits (64), Expect = 4.6
Identities = 15/61 (24%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 58 PYGVLYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGS---HNKKRPNNLVIGRMYDYHVL 114
P G LYK+ + F++Q + + +D ++ G H +P NL++G + +
Sbjct: 158 PRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIA 217
Query: 115 D 115
D
Sbjct: 218 D 218
>gi|237681069 spatacsin isoform 2 [Homo sapiens]
Length = 2330
Score = 29.3 bits (64), Expect = 4.6
Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 155 DYRRLKSLLIDFFRGPTVSNIRLAGLEYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIEL 214
+Y+ ++ L++F + N + V+ L ++ F KL+L++ C+T
Sbjct: 1564 NYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFL-LKLMLQQ--CKTQY--- 1617
Query: 215 EEMGPSLDLVLRRTHLASD--DLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQ--- 269
E+G L L + R HL SD D+ KL + + + LK I+H T T+Y ++Q
Sbjct: 1618 -ELGKLLQLFVEREHLFSDGPDVKKLCI-LCQILKDTSIA-INH-TIITSYSIENLQHEC 1673
Query: 270 KQDLSKLQTRKMKGLKKRPAE 290
+ L +LQT L +R AE
Sbjct: 1674 RSILERLQTDGQFALARRVAE 1694
>gi|93204888 spatacsin isoform 1 [Homo sapiens]
Length = 2443
Score = 29.3 bits (64), Expect = 4.6
Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 155 DYRRLKSLLIDFFRGPTVSNIRLAGLEYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIEL 214
+Y+ ++ L++F + N + V+ L ++ F KL+L++ C+T
Sbjct: 1564 NYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFL-LKLMLQQ--CKTQY--- 1617
Query: 215 EEMGPSLDLVLRRTHLASD--DLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQ--- 269
E+G L L + R HL SD D+ KL + + + LK I+H T T+Y ++Q
Sbjct: 1618 -ELGKLLQLFVEREHLFSDGPDVKKLCI-LCQILKDTSIA-INH-TIITSYSIENLQHEC 1673
Query: 270 KQDLSKLQTRKMKGLKKRPAE 290
+ L +LQT L +R AE
Sbjct: 1674 RSILERLQTDGQFALARRVAE 1694
>gi|27883882 P18SRP protein [Homo sapiens]
Length = 155
Score = 29.3 bits (64), Expect = 4.6
Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 237 KLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDH 296
K K + +K KKK+ S+ + T +KQ K + +K K K + + H
Sbjct: 76 KKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKH----H 131
Query: 297 EKKSKRIKK 305
+K+ K+ KK
Sbjct: 132 KKEKKKRKK 140
>gi|166706917 hypothetical protein LOC199920 [Homo sapiens]
Length = 728
Score = 29.3 bits (64), Expect = 4.6
Identities = 21/66 (31%), Positives = 29/66 (43%)
Query: 232 SDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAER 291
S D KL M PK L PK+KK + ++ + K L+ +MK +K ER
Sbjct: 597 SKDEDKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRER 656
Query: 292 ITEDHE 297
D E
Sbjct: 657 FKYDKE 662
>gi|154800469 lung cancer-related protein 8 isoform c [Homo sapiens]
Length = 583
Score = 28.9 bits (63), Expect = 6.0
Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 11/86 (12%)
Query: 7 VVKPKTKRAKRFLEKREPKL-----NENIKNAMLIKGGNANATVTKVLKDVYALKKPYGV 61
++K K K + E+R KL + +K L G A TK KD+ K P
Sbjct: 62 LIKAKGKELETENEERNSKLVVDKPEQTVKTFPLPAVGLERAATTKADKDI---KNPIQP 118
Query: 62 LYKKKNITRP---FEDQTSLEFFSKK 84
+K T+P F+++T +F++ +
Sbjct: 119 SFKMLKNTKPMTTFQEETKAQFYASE 144
>gi|154800467 lung cancer-related protein 8 isoform b [Homo sapiens]
Length = 573
Score = 28.9 bits (63), Expect = 6.0
Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 11/86 (12%)
Query: 7 VVKPKTKRAKRFLEKREPKL-----NENIKNAMLIKGGNANATVTKVLKDVYALKKPYGV 61
++K K K + E+R KL + +K L G A TK KD+ K P
Sbjct: 62 LIKAKGKELETENEERNSKLVVDKPEQTVKTFPLPAVGLERAATTKADKDI---KNPIQP 118
Query: 62 LYKKKNITRP---FEDQTSLEFFSKK 84
+K T+P F+++T +F++ +
Sbjct: 119 SFKMLKNTKPMTTFQEETKAQFYASE 144
>gi|21361664 lung cancer-related protein 8 isoform a [Homo sapiens]
Length = 609
Score = 28.9 bits (63), Expect = 6.0
Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 11/86 (12%)
Query: 7 VVKPKTKRAKRFLEKREPKL-----NENIKNAMLIKGGNANATVTKVLKDVYALKKPYGV 61
++K K K + E+R KL + +K L G A TK KD+ K P
Sbjct: 62 LIKAKGKELETENEERNSKLVVDKPEQTVKTFPLPAVGLERAATTKADKDI---KNPIQP 118
Query: 62 LYKKKNITRP---FEDQTSLEFFSKK 84
+K T+P F+++T +F++ +
Sbjct: 119 SFKMLKNTKPMTTFQEETKAQFYASE 144
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 28.5 bits (62), Expect = 7.8
Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 21/105 (20%)
Query: 200 LLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTF 259
LL +SG IE+EE + +S + KLS + ++K+IS D
Sbjct: 1117 LLEDESGTEAAPIEMEEAS------VYSQWSSSTSVIKLSKDVDS-----QEKDISKDHI 1165
Query: 260 GTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDHEKKSKRIK 304
T L +LQ + K KK A+++ + H+KK K K
Sbjct: 1166 ALT----------LKRLQKIRDKRDKKATAQKLKKKHKKKGKEAK 1200
>gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens]
Length = 4363
Score = 28.5 bits (62), Expect = 7.8
Identities = 18/73 (24%), Positives = 32/73 (43%)
Query: 214 LEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDL 273
++ G DL++ S D+ S++ +A P N++H T G T L
Sbjct: 1009 MQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSL 1068
Query: 274 SKLQTRKMKGLKK 286
K+ T++ + L K
Sbjct: 1069 DKILTKEQESLIK 1081
>gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens]
Length = 4388
Score = 28.5 bits (62), Expect = 7.8
Identities = 18/73 (24%), Positives = 32/73 (43%)
Query: 214 LEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDL 273
++ G DL++ S D+ S++ +A P N++H T G T L
Sbjct: 1009 MQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSL 1068
Query: 274 SKLQTRKMKGLKK 286
K+ T++ + L K
Sbjct: 1069 DKILTKEQESLIK 1081
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,028,846
Number of Sequences: 37866
Number of extensions: 466029
Number of successful extensions: 1274
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1253
Number of HSP's gapped (non-prelim): 29
length of query: 306
length of database: 18,247,518
effective HSP length: 102
effective length of query: 204
effective length of database: 14,385,186
effective search space: 2934577944
effective search space used: 2934577944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.