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Search of human proteins with 38524620
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38524620 prickle-like 2 [Homo sapiens]
(844 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38524620 prickle-like 2 [Homo sapiens] 1761 0.0
gi|222136684 prickle homolog 1 [Homo sapiens] 766 0.0
gi|222136682 prickle homolog 1 [Homo sapiens] 766 0.0
gi|222136680 prickle homolog 1 [Homo sapiens] 766 0.0
gi|222136678 prickle homolog 1 [Homo sapiens] 766 0.0
gi|7710129 LIM domain only 6 [Homo sapiens] 545 e-155
gi|7661666 testin isoform 1 [Homo sapiens] 255 1e-67
gi|23238188 testin isoform 2 [Homo sapiens] 255 1e-67
gi|118722347 over-expressed breast tumor protein [Homo sapiens] 219 6e-57
gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens] 179 1e-44
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 111 2e-24
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 103 7e-22
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 103 7e-22
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 101 3e-21
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 100 7e-21
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 100 7e-21
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 100 7e-21
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 100 7e-21
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 100 7e-21
gi|109638745 transforming growth factor beta 1 induced transcrip... 100 7e-21
gi|21361591 transforming growth factor beta 1 induced transcript... 100 7e-21
gi|30410801 activator of cAMP-responsive element modulator (CREM... 100 7e-21
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 98 4e-20
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 98 4e-20
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 98 4e-20
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 98 4e-20
gi|170932518 paxillin isoform 3 [Homo sapiens] 97 8e-20
gi|170932516 paxillin isoform 2 [Homo sapiens] 97 8e-20
gi|170932514 paxillin isoform 1 [Homo sapiens] 97 8e-20
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 94 5e-19
>gi|38524620 prickle-like 2 [Homo sapiens]
Length = 844
Score = 1761 bits (4560), Expect = 0.0
Identities = 844/844 (100%), Positives = 844/844 (100%)
Query: 1 MVTVMPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEK 60
MVTVMPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEK
Sbjct: 1 MVTVMPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEK 60
Query: 61 VPYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRP 120
VPYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRP
Sbjct: 61 VPYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRP 120
Query: 121 FPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGK 180
FPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGK
Sbjct: 121 FPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGK 180
Query: 181 IYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGR 240
IYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGR
Sbjct: 181 IYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGR 240
Query: 241 PYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPK 300
PYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPK
Sbjct: 241 PYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPK 300
Query: 301 QGQIFCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEEPMLNQHSQLQV 360
QGQIFCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEEPMLNQHSQLQV
Sbjct: 301 QGQIFCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEEPMLNQHSQLQV 360
Query: 361 SSNRLSADVDPLSLQMDMLSLSSQTPSLNRDPIWRSREEPYHYGNKMEQNQTQSPLQLLS 420
SSNRLSADVDPLSLQMDMLSLSSQTPSLNRDPIWRSREEPYHYGNKMEQNQTQSPLQLLS
Sbjct: 361 SSNRLSADVDPLSLQMDMLSLSSQTPSLNRDPIWRSREEPYHYGNKMEQNQTQSPLQLLS 420
Query: 421 QCNIRTSYSPGGQGAGAQPEMWGKHFSNPKRSSSLAMTGHAGSFIKECREDYYPGRLRSQ 480
QCNIRTSYSPGGQGAGAQPEMWGKHFSNPKRSSSLAMTGHAGSFIKECREDYYPGRLRSQ
Sbjct: 421 QCNIRTSYSPGGQGAGAQPEMWGKHFSNPKRSSSLAMTGHAGSFIKECREDYYPGRLRSQ 480
Query: 481 ESYSDMSSQSFSETRGSIQVPKYEEEEEEEGGLSTQQCRTRHPISSLKYTEDMTPTEQTP 540
ESYSDMSSQSFSETRGSIQVPKYEEEEEEEGGLSTQQCRTRHPISSLKYTEDMTPTEQTP
Sbjct: 481 ESYSDMSSQSFSETRGSIQVPKYEEEEEEEGGLSTQQCRTRHPISSLKYTEDMTPTEQTP 540
Query: 541 RGSMESLALSNATGLSADGGAKRQEHLSRFSMPDLSKDSGMNVSEKLSNMGTLNSSMQFR 600
RGSMESLALSNATGLSADGGAKRQEHLSRFSMPDLSKDSGMNVSEKLSNMGTLNSSMQFR
Sbjct: 541 RGSMESLALSNATGLSADGGAKRQEHLSRFSMPDLSKDSGMNVSEKLSNMGTLNSSMQFR 600
Query: 601 SAESVRSLLSAQQYQEMEGNLHQLSNPIGYRDLQSHGRMHQSFDFDGGMAGSKLPGQEGV 660
SAESVRSLLSAQQYQEMEGNLHQLSNPIGYRDLQSHGRMHQSFDFDGGMAGSKLPGQEGV
Sbjct: 601 SAESVRSLLSAQQYQEMEGNLHQLSNPIGYRDLQSHGRMHQSFDFDGGMAGSKLPGQEGV 660
Query: 661 RIQPMSERTRRRATSRDDNRRFRPHRSRRSRRSRSDNALHLASEREAISRLKDRPPLRAR 720
RIQPMSERTRRRATSRDDNRRFRPHRSRRSRRSRSDNALHLASEREAISRLKDRPPLRAR
Sbjct: 661 RIQPMSERTRRRATSRDDNRRFRPHRSRRSRRSRSDNALHLASEREAISRLKDRPPLRAR 720
Query: 721 EDYDQFMRQRSFQESMGHGSRRDLYGQCPRTVSDLALQNAFGDRWGPYFAEYDWCSTCSS 780
EDYDQFMRQRSFQESMGHGSRRDLYGQCPRTVSDLALQNAFGDRWGPYFAEYDWCSTCSS
Sbjct: 721 EDYDQFMRQRSFQESMGHGSRRDLYGQCPRTVSDLALQNAFGDRWGPYFAEYDWCSTCSS 780
Query: 781 SSESDNEGYFLGEPIPQPARLRYVTSDELLHKYSSYGLPKSSTLGGRGQLHSRKRQKSKN 840
SSESDNEGYFLGEPIPQPARLRYVTSDELLHKYSSYGLPKSSTLGGRGQLHSRKRQKSKN
Sbjct: 781 SSESDNEGYFLGEPIPQPARLRYVTSDELLHKYSSYGLPKSSTLGGRGQLHSRKRQKSKN 840
Query: 841 CIIS 844
CIIS
Sbjct: 841 CIIS 844
>gi|222136684 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 766 bits (1979), Expect = 0.0
Identities = 429/851 (50%), Positives = 542/851 (63%), Gaps = 31/851 (3%)
Query: 5 MPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYV 64
MPLEME +SKL F QR+STSDDDSGCALEEYAWVPPGL+PEQ+ Y++CLPEEKVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 65 NSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPFPVT 124
NSPGEK RIKQLL+QLPPHDNEVRYC SL EEEK+EL++FS+QRK+E LGRG ++
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 125 MTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCG 184
+ A+CEQCG +INGG++AVFASRAG GVCWHP CFVC CNELLVDLIYFYQDGKI+CG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 185 RHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCC 244
RHHAE LKPRC+ACDEIIFADECTEAEGRHWHMKHFCC ECETVLGGQRYIMK+GRP+CC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 245 HCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQI 304
CFESLYAEYC+TC +HIG+D QMTYDGQHWHATE CF CA CK SLLG PFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 305 FCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEE--PMLNQHSQLQVSS 362
+CS+ CS GED + SDSSDSAFQ+AR+++SRRS ++GK+ ++ L L
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
Query: 363 NRLSADV-DPLSLQMDMLSLSSQTPSLNRDPIWRSREEPYHYGNKMEQNQTQSPL-QLLS 420
LS + D LS ++D LSLS Q S + W+ R E + E + + QLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
Query: 421 QCNIRTSYSPGGQGAGAQ-PEMWGKHFSNPKRSSSLAMTGHAGSFIKECREDYYPGRLRS 479
+ ++ + P + E W N +S + + K+ + D Y
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWIS--DNMVKSKTELKQNNQSLASKKYQSDMY-----W 473
Query: 480 QESYSDMSSQSFSETRGSIQVPKYEEEEEEEGGLSTQQCRTRHPISSLKYTEDMTPTEQT 539
+S + ++ G + +E E + G T+ SL+ D+ P EQ+
Sbjct: 474 AQSQDGLGDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKP-EQS 532
Query: 540 PRGSMESLALSNATGLSADGGAKRQEHLSRFSMPDLSKDSGMNVS--EKLSNMGTLNSSM 597
R SM+SLALSN TG S DG E+ R S+ L M EK+SNMGTLNSSM
Sbjct: 533 VRDSMDSLALSNITGASVDG-----ENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSM 587
Query: 598 QFRSAESVRSLLSAQQYQEMEGNLHQLSNPIGYRDLQSHGRMHQSFDFDGGMAGSKLPGQ 657
RSAES++SL S +++ + P+ R +S R Q D + +
Sbjct: 588 LHRSAESLKSLSSELCPEKILPEEKPVHLPV-LRRSKSQSRPQQVKFSDDVIDNGNYDIE 646
Query: 658 EGVRIQPMSERTRRRATSRDD-NRRFRPHRSRRSRRSRSDNALHLASEREAISRLKDRPP 716
+R PMSERTRRR + ++ R HR RRSR+SRSDNAL+L +ER+ KDR
Sbjct: 647 --IRQPPMSERTRRRVYNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSP--KDRLR 702
Query: 717 LRAREDYDQFMRQRSFQESMGHGSRRDLYGQCPRTVSDLALQNAFGDRWGPYFAEYD--W 774
L ++Y++F++ +S +E + DLYGQ SD LQN +R+ + E D W
Sbjct: 703 LYTPDNYEKFIQNKSAREIQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSW 762
Query: 775 CSTCSSSSESDNEGYFLGEPIPQPARLRYV-TSDELLHKYSSYGLPKSSTLGGRGQLHSR 833
CS+ SSSS+S+ EGYFLG+PIPQP R+ +D+L S+ P+ + + +
Sbjct: 763 CSSSSSSSDSEEEGYFLGQPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSK--KK 820
Query: 834 KRQKSKNCIIS 844
K K KNCIIS
Sbjct: 821 KGHKGKNCIIS 831
>gi|222136682 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 766 bits (1979), Expect = 0.0
Identities = 429/851 (50%), Positives = 542/851 (63%), Gaps = 31/851 (3%)
Query: 5 MPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYV 64
MPLEME +SKL F QR+STSDDDSGCALEEYAWVPPGL+PEQ+ Y++CLPEEKVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 65 NSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPFPVT 124
NSPGEK RIKQLL+QLPPHDNEVRYC SL EEEK+EL++FS+QRK+E LGRG ++
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 125 MTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCG 184
+ A+CEQCG +INGG++AVFASRAG GVCWHP CFVC CNELLVDLIYFYQDGKI+CG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 185 RHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCC 244
RHHAE LKPRC+ACDEIIFADECTEAEGRHWHMKHFCC ECETVLGGQRYIMK+GRP+CC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 245 HCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQI 304
CFESLYAEYC+TC +HIG+D QMTYDGQHWHATE CF CA CK SLLG PFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 305 FCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEE--PMLNQHSQLQVSS 362
+CS+ CS GED + SDSSDSAFQ+AR+++SRRS ++GK+ ++ L L
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
Query: 363 NRLSADV-DPLSLQMDMLSLSSQTPSLNRDPIWRSREEPYHYGNKMEQNQTQSPL-QLLS 420
LS + D LS ++D LSLS Q S + W+ R E + E + + QLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
Query: 421 QCNIRTSYSPGGQGAGAQ-PEMWGKHFSNPKRSSSLAMTGHAGSFIKECREDYYPGRLRS 479
+ ++ + P + E W N +S + + K+ + D Y
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWIS--DNMVKSKTELKQNNQSLASKKYQSDMY-----W 473
Query: 480 QESYSDMSSQSFSETRGSIQVPKYEEEEEEEGGLSTQQCRTRHPISSLKYTEDMTPTEQT 539
+S + ++ G + +E E + G T+ SL+ D+ P EQ+
Sbjct: 474 AQSQDGLGDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKP-EQS 532
Query: 540 PRGSMESLALSNATGLSADGGAKRQEHLSRFSMPDLSKDSGMNVS--EKLSNMGTLNSSM 597
R SM+SLALSN TG S DG E+ R S+ L M EK+SNMGTLNSSM
Sbjct: 533 VRDSMDSLALSNITGASVDG-----ENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSM 587
Query: 598 QFRSAESVRSLLSAQQYQEMEGNLHQLSNPIGYRDLQSHGRMHQSFDFDGGMAGSKLPGQ 657
RSAES++SL S +++ + P+ R +S R Q D + +
Sbjct: 588 LHRSAESLKSLSSELCPEKILPEEKPVHLPV-LRRSKSQSRPQQVKFSDDVIDNGNYDIE 646
Query: 658 EGVRIQPMSERTRRRATSRDD-NRRFRPHRSRRSRRSRSDNALHLASEREAISRLKDRPP 716
+R PMSERTRRR + ++ R HR RRSR+SRSDNAL+L +ER+ KDR
Sbjct: 647 --IRQPPMSERTRRRVYNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSP--KDRLR 702
Query: 717 LRAREDYDQFMRQRSFQESMGHGSRRDLYGQCPRTVSDLALQNAFGDRWGPYFAEYD--W 774
L ++Y++F++ +S +E + DLYGQ SD LQN +R+ + E D W
Sbjct: 703 LYTPDNYEKFIQNKSAREIQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSW 762
Query: 775 CSTCSSSSESDNEGYFLGEPIPQPARLRYV-TSDELLHKYSSYGLPKSSTLGGRGQLHSR 833
CS+ SSSS+S+ EGYFLG+PIPQP R+ +D+L S+ P+ + + +
Sbjct: 763 CSSSSSSSDSEEEGYFLGQPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSK--KK 820
Query: 834 KRQKSKNCIIS 844
K K KNCIIS
Sbjct: 821 KGHKGKNCIIS 831
>gi|222136680 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 766 bits (1979), Expect = 0.0
Identities = 429/851 (50%), Positives = 542/851 (63%), Gaps = 31/851 (3%)
Query: 5 MPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYV 64
MPLEME +SKL F QR+STSDDDSGCALEEYAWVPPGL+PEQ+ Y++CLPEEKVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 65 NSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPFPVT 124
NSPGEK RIKQLL+QLPPHDNEVRYC SL EEEK+EL++FS+QRK+E LGRG ++
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 125 MTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCG 184
+ A+CEQCG +INGG++AVFASRAG GVCWHP CFVC CNELLVDLIYFYQDGKI+CG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 185 RHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCC 244
RHHAE LKPRC+ACDEIIFADECTEAEGRHWHMKHFCC ECETVLGGQRYIMK+GRP+CC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 245 HCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQI 304
CFESLYAEYC+TC +HIG+D QMTYDGQHWHATE CF CA CK SLLG PFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 305 FCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEE--PMLNQHSQLQVSS 362
+CS+ CS GED + SDSSDSAFQ+AR+++SRRS ++GK+ ++ L L
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
Query: 363 NRLSADV-DPLSLQMDMLSLSSQTPSLNRDPIWRSREEPYHYGNKMEQNQTQSPL-QLLS 420
LS + D LS ++D LSLS Q S + W+ R E + E + + QLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
Query: 421 QCNIRTSYSPGGQGAGAQ-PEMWGKHFSNPKRSSSLAMTGHAGSFIKECREDYYPGRLRS 479
+ ++ + P + E W N +S + + K+ + D Y
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWIS--DNMVKSKTELKQNNQSLASKKYQSDMY-----W 473
Query: 480 QESYSDMSSQSFSETRGSIQVPKYEEEEEEEGGLSTQQCRTRHPISSLKYTEDMTPTEQT 539
+S + ++ G + +E E + G T+ SL+ D+ P EQ+
Sbjct: 474 AQSQDGLGDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKP-EQS 532
Query: 540 PRGSMESLALSNATGLSADGGAKRQEHLSRFSMPDLSKDSGMNVS--EKLSNMGTLNSSM 597
R SM+SLALSN TG S DG E+ R S+ L M EK+SNMGTLNSSM
Sbjct: 533 VRDSMDSLALSNITGASVDG-----ENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSM 587
Query: 598 QFRSAESVRSLLSAQQYQEMEGNLHQLSNPIGYRDLQSHGRMHQSFDFDGGMAGSKLPGQ 657
RSAES++SL S +++ + P+ R +S R Q D + +
Sbjct: 588 LHRSAESLKSLSSELCPEKILPEEKPVHLPV-LRRSKSQSRPQQVKFSDDVIDNGNYDIE 646
Query: 658 EGVRIQPMSERTRRRATSRDD-NRRFRPHRSRRSRRSRSDNALHLASEREAISRLKDRPP 716
+R PMSERTRRR + ++ R HR RRSR+SRSDNAL+L +ER+ KDR
Sbjct: 647 --IRQPPMSERTRRRVYNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSP--KDRLR 702
Query: 717 LRAREDYDQFMRQRSFQESMGHGSRRDLYGQCPRTVSDLALQNAFGDRWGPYFAEYD--W 774
L ++Y++F++ +S +E + DLYGQ SD LQN +R+ + E D W
Sbjct: 703 LYTPDNYEKFIQNKSAREIQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSW 762
Query: 775 CSTCSSSSESDNEGYFLGEPIPQPARLRYV-TSDELLHKYSSYGLPKSSTLGGRGQLHSR 833
CS+ SSSS+S+ EGYFLG+PIPQP R+ +D+L S+ P+ + + +
Sbjct: 763 CSSSSSSSDSEEEGYFLGQPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSK--KK 820
Query: 834 KRQKSKNCIIS 844
K K KNCIIS
Sbjct: 821 KGHKGKNCIIS 831
>gi|222136678 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 766 bits (1979), Expect = 0.0
Identities = 429/851 (50%), Positives = 542/851 (63%), Gaps = 31/851 (3%)
Query: 5 MPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYV 64
MPLEME +SKL F QR+STSDDDSGCALEEYAWVPPGL+PEQ+ Y++CLPEEKVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 65 NSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPFPVT 124
NSPGEK RIKQLL+QLPPHDNEVRYC SL EEEK+EL++FS+QRK+E LGRG ++
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 125 MTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCG 184
+ A+CEQCG +INGG++AVFASRAG GVCWHP CFVC CNELLVDLIYFYQDGKI+CG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 185 RHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCC 244
RHHAE LKPRC+ACDEIIFADECTEAEGRHWHMKHFCC ECETVLGGQRYIMK+GRP+CC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 245 HCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQI 304
CFESLYAEYC+TC +HIG+D QMTYDGQHWHATE CF CA CK SLLG PFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 305 FCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEE--PMLNQHSQLQVSS 362
+CS+ CS GED + SDSSDSAFQ+AR+++SRRS ++GK+ ++ L L
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
Query: 363 NRLSADV-DPLSLQMDMLSLSSQTPSLNRDPIWRSREEPYHYGNKMEQNQTQSPL-QLLS 420
LS + D LS ++D LSLS Q S + W+ R E + E + + QLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
Query: 421 QCNIRTSYSPGGQGAGAQ-PEMWGKHFSNPKRSSSLAMTGHAGSFIKECREDYYPGRLRS 479
+ ++ + P + E W N +S + + K+ + D Y
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWIS--DNMVKSKTELKQNNQSLASKKYQSDMY-----W 473
Query: 480 QESYSDMSSQSFSETRGSIQVPKYEEEEEEEGGLSTQQCRTRHPISSLKYTEDMTPTEQT 539
+S + ++ G + +E E + G T+ SL+ D+ P EQ+
Sbjct: 474 AQSQDGLGDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKP-EQS 532
Query: 540 PRGSMESLALSNATGLSADGGAKRQEHLSRFSMPDLSKDSGMNVS--EKLSNMGTLNSSM 597
R SM+SLALSN TG S DG E+ R S+ L M EK+SNMGTLNSSM
Sbjct: 533 VRDSMDSLALSNITGASVDG-----ENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSM 587
Query: 598 QFRSAESVRSLLSAQQYQEMEGNLHQLSNPIGYRDLQSHGRMHQSFDFDGGMAGSKLPGQ 657
RSAES++SL S +++ + P+ R +S R Q D + +
Sbjct: 588 LHRSAESLKSLSSELCPEKILPEEKPVHLPV-LRRSKSQSRPQQVKFSDDVIDNGNYDIE 646
Query: 658 EGVRIQPMSERTRRRATSRDD-NRRFRPHRSRRSRRSRSDNALHLASEREAISRLKDRPP 716
+R PMSERTRRR + ++ R HR RRSR+SRSDNAL+L +ER+ KDR
Sbjct: 647 --IRQPPMSERTRRRVYNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSP--KDRLR 702
Query: 717 LRAREDYDQFMRQRSFQESMGHGSRRDLYGQCPRTVSDLALQNAFGDRWGPYFAEYD--W 774
L ++Y++F++ +S +E + DLYGQ SD LQN +R+ + E D W
Sbjct: 703 LYTPDNYEKFIQNKSAREIQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSW 762
Query: 775 CSTCSSSSESDNEGYFLGEPIPQPARLRYV-TSDELLHKYSSYGLPKSSTLGGRGQLHSR 833
CS+ SSSS+S+ EGYFLG+PIPQP R+ +D+L S+ P+ + + +
Sbjct: 763 CSSSSSSSDSEEEGYFLGQPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSK--KK 820
Query: 834 KRQKSKNCIIS 844
K K KNCIIS
Sbjct: 821 KGHKGKNCIIS 831
>gi|7710129 LIM domain only 6 [Homo sapiens]
Length = 615
Score = 545 bits (1405), Expect = e-155
Identities = 234/321 (72%), Positives = 276/321 (85%)
Query: 2 VTVMPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKV 61
V +P+++E+ + +L+ DFQR+S SDDDSGCA EEYAWVPPGLKPEQV+Q++SCLPE+KV
Sbjct: 58 VHAVPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKV 117
Query: 62 PYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPF 121
PYVNSPGEK RIKQLLHQLPPHD+E +YC +L+EEEK+EL+ FS QRKRENLGRG VR F
Sbjct: 118 PYVNSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIF 177
Query: 122 PVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKI 181
PVT+TGAICE+CG QI GGDIAVFASRAG G CWHP CFVCT C ELLVDLIYFY GK+
Sbjct: 178 PVTITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKV 237
Query: 182 YCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRP 241
YCGRHHAECL+PRC ACDEIIF+ ECTEAEGRHWHM HFCCFECE LGGQRY+M++ RP
Sbjct: 238 YCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRP 297
Query: 242 YCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQ 301
+CC C+E+ +AEYCD C +HIG+DQGQM Y+GQHWHA++ CFCC+ C ++LLGRPFLP++
Sbjct: 298 HCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRR 357
Query: 302 GQIFCSRACSAGEDPNGSDSS 322
G IFCSRACS G +P S
Sbjct: 358 GLIFCSRACSLGSEPTAPGPS 378
Score = 36.2 bits (82), Expect = 0.13
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 10/70 (14%)
Query: 779 SSSSESDNEGYFLGEPIPQPARL--RYVTSDELLHKYS--SYGLPKSSTLGGRGQLHSRK 834
SSS S+++G+FLGE IP P L D + ++ S LP+ S G +
Sbjct: 552 SSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMETFNSPSLSLPRDSRAG------MPR 605
Query: 835 RQKSKNCIIS 844
+ + KNCI++
Sbjct: 606 QARDKNCIVA 615
>gi|7661666 testin isoform 1 [Homo sapiens]
Length = 421
Score = 255 bits (652), Expect = 1e-67
Identities = 121/307 (39%), Positives = 172/307 (56%), Gaps = 34/307 (11%)
Query: 37 YAWVPPGLKPEQVHQYYSCLPEEKVPYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEE 96
Y W PP QY LP+EK P S G + R KQL QLP HD + C+ L
Sbjct: 111 YEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPR 170
Query: 97 EKRELKLFSSQRKRENLGRGNVRPFPVTM--------------------TGAI------- 129
E +E++ F + K E LG G+V+ P M GA+
Sbjct: 171 EVKEMEQFVKKYKSEALGVGDVK-LPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEH 229
Query: 130 ------CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYC 183
C C + GD A++A RAG+ WHP CFVC+ C+ELLVD+IYF+++ K+YC
Sbjct: 230 KRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYC 289
Query: 184 GRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYC 243
GRH+ + KPRCA CDE+IF++E T+AE ++WH+KHFCCF+C+++L G+ Y+M +P C
Sbjct: 290 GRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVC 349
Query: 244 CHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQ 303
C+ +A C C I + ++TY+ WHA+ CF C+ C K L+G+ F+P +G
Sbjct: 350 KPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGM 409
Query: 304 IFCSRAC 310
+FCS C
Sbjct: 410 VFCSVEC 416
Score = 31.6 bits (70), Expect = 3.2
Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 34/125 (27%)
Query: 204 ADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIG 263
A E AE + +CC + MKEG P ++YAE
Sbjct: 221 AMEDKSAEHKRTQYSCYCC----------KLSMKEGDP-------AIYAE---------- 253
Query: 264 IDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGEDPNGSDSSD 323
+ YD + WH CF C+ C + L+ + K +++C R E P + +
Sbjct: 254 ----RAGYD-KLWHPA--CFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDE 306
Query: 324 SAFQN 328
F N
Sbjct: 307 LIFSN 311
>gi|23238188 testin isoform 2 [Homo sapiens]
Length = 412
Score = 255 bits (652), Expect = 1e-67
Identities = 121/307 (39%), Positives = 172/307 (56%), Gaps = 34/307 (11%)
Query: 37 YAWVPPGLKPEQVHQYYSCLPEEKVPYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEE 96
Y W PP QY LP+EK P S G + R KQL QLP HD + C+ L
Sbjct: 102 YEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPR 161
Query: 97 EKRELKLFSSQRKRENLGRGNVRPFPVTM--------------------TGAI------- 129
E +E++ F + K E LG G+V+ P M GA+
Sbjct: 162 EVKEMEQFVKKYKSEALGVGDVK-LPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEH 220
Query: 130 ------CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYC 183
C C + GD A++A RAG+ WHP CFVC+ C+ELLVD+IYF+++ K+YC
Sbjct: 221 KRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYC 280
Query: 184 GRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYC 243
GRH+ + KPRCA CDE+IF++E T+AE ++WH+KHFCCF+C+++L G+ Y+M +P C
Sbjct: 281 GRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVC 340
Query: 244 CHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQ 303
C+ +A C C I + ++TY+ WHA+ CF C+ C K L+G+ F+P +G
Sbjct: 341 KPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGM 400
Query: 304 IFCSRAC 310
+FCS C
Sbjct: 401 VFCSVEC 407
Score = 31.6 bits (70), Expect = 3.2
Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 34/125 (27%)
Query: 204 ADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIG 263
A E AE + +CC + MKEG P ++YAE
Sbjct: 212 AMEDKSAEHKRTQYSCYCC----------KLSMKEGDP-------AIYAE---------- 244
Query: 264 IDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGEDPNGSDSSD 323
+ YD + WH CF C+ C + L+ + K +++C R E P + +
Sbjct: 245 ----RAGYD-KLWHPA--CFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDE 297
Query: 324 SAFQN 328
F N
Sbjct: 298 LIFSN 302
>gi|118722347 over-expressed breast tumor protein [Homo sapiens]
Length = 384
Score = 219 bits (559), Expect = 6e-57
Identities = 109/238 (45%), Positives = 141/238 (59%), Gaps = 22/238 (9%)
Query: 24 STSDDDSGCALEEYAWVPPGLKPEQVHQYYS--------CLPEEKVPYVNSPGEKLRIKQ 75
+ SD DSG PG PE H CL + P N G ++
Sbjct: 24 ANSDSDSGHL--------PGEDPEDTHAQGPAVLSLGSLCLDTNQAP--NWTG----LQT 69
Query: 76 LLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPFPVTMTGAICEQCGG 135
LL QLPP D + RYC +L EEE+ EL+LF ++RK+E LG+G R + G CE+C
Sbjct: 70 LLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRE 129
Query: 136 QINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRC 195
+ G+ VFA+RAG CWH PCF C C + L++LIYFY DG++YCGRHHAE L+PRC
Sbjct: 130 LLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRC 189
Query: 196 AACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAE 253
ACD++IF+ CTEAEG+ WH HFCC +C LGG RY + G P C CFE+ Y++
Sbjct: 190 PACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
Score = 38.1 bits (87), Expect = 0.034
Identities = 16/22 (72%), Positives = 20/22 (90%)
Query: 776 STCSSSSESDNEGYFLGEPIPQ 797
STCSSSS+S+ EG+FLGE +PQ
Sbjct: 340 STCSSSSDSEPEGFFLGERLPQ 361
Score = 30.4 bits (67), Expect = 7.2
Identities = 11/33 (33%), Positives = 18/33 (54%), Gaps = 2/33 (6%)
Query: 276 WHATETCFCCAHCKKSLLGRPFLPKQGQIFCSR 308
WH + CF C C ++L+ + GQ++C R
Sbjct: 149 WH--QPCFACQACGQALINLIYFYHDGQLYCGR 179
>gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens]
Length = 365
Score = 179 bits (454), Expect = 1e-44
Identities = 94/245 (38%), Positives = 126/245 (51%), Gaps = 32/245 (13%)
Query: 37 YAWVPPGLKPEQVHQYYSCLPEEKVPYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEE 96
Y W PPG+ + QY +P+EK P + G R +QL+HQLP +D + C L E
Sbjct: 118 YEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLEN 177
Query: 97 EKRELKLFSSQRKRENLGRGNV-----------------RPFPVTMTGA----------- 128
E + ++ F Q K E LG G V +P T A
Sbjct: 178 ELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSK 237
Query: 129 ----ICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCG 184
+CE C G V++ RAG+ WHP CFVC C+E LVDLIYF++DG +CG
Sbjct: 238 EVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCG 297
Query: 185 RHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCC 244
RH+ E L+PRC+ CDEIIFA++ E WH KHF C CE +L G+ YI+ +G+ C
Sbjct: 298 RHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCP 357
Query: 245 HCFES 249
C +S
Sbjct: 358 TCSKS 362
Score = 30.0 bits (66), Expect = 9.4
Identities = 13/35 (37%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSR 308
+ WH T CF CA C + L+ + K G +C R
Sbjct: 266 KQWHPT--CFVCAKCSEPLVDLIYFWKDGAPWCGR 298
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 111 bits (278), Expect = 2e-24
Identities = 58/186 (31%), Positives = 89/186 (47%), Gaps = 9/186 (4%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C CG + G + G WH CF+C+ C + L + G YC +
Sbjct: 101 CSACGETVMPGSRKLEYG----GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYEN 156
Query: 190 CLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFES 249
PRCA C + + T + + WH + C C+T L GQ++ ++ PYC CF
Sbjct: 157 KFAPRCARCSKTLTQGGVTYRD-QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGE 215
Query: 250 LYAEYCDTCAQHI-GIDQGQ-MTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCS 307
L+A C +C + I G+ G+ ++++ +HWH CF CA C SL+G+ F+P Q+ C
Sbjct: 216 LFAPKCSSCKRPIVGLGGGKYVSFEDRHWH--HNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
Query: 308 RACSAG 313
AG
Sbjct: 274 GCSQAG 279
Score = 93.2 bits (230), Expect = 9e-19
Identities = 46/153 (30%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIF-ADECTEAEGR 213
+H CF C C L D + QD ++ C + +C+AC E + E G+
Sbjct: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
Query: 214 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDG 273
WH F C CE LG + ++ +G YC C+E+ +A C C++ + QG +TY
Sbjct: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSK--TLTQGGVTYRD 178
Query: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
Q WH C C C+ L G+ F + +C
Sbjct: 179 QPWH--RECLVCTGCQTPLAGQQFTSRDEDPYC 209
Score = 83.2 bits (204), Expect = 9e-16
Identities = 44/148 (29%), Positives = 66/148 (44%), Gaps = 3/148 (2%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEA-EGRHWHMK 218
F C CNE L Y D YC + CA C ++I D E RH+H
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
Query: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278
F C C+ L + + ++ C C+ S ++ C C + + ++ Y GQ WH
Sbjct: 65 CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWH- 123
Query: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC 306
E CF C+ C++ L R F+P +G +C
Sbjct: 124 -EHCFLCSGCEQPLGSRSFVPDKGAHYC 150
Score = 76.6 bits (187), Expect = 9e-14
Identities = 34/94 (36%), Positives = 53/94 (56%), Gaps = 3/94 (3%)
Query: 220 FCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHAT 279
F C +C L G++YI + PYC C+++ +A C C Q IG D ++ Y+ +H+H
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH-- 62
Query: 280 ETCFCCAHCKKSLLGRPFLPKQGQIFCSRA-CSA 312
E CF C C++SL PF + ++ C+ CSA
Sbjct: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSA 96
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 103 bits (257), Expect = 7e-22
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 12/199 (6%)
Query: 113 LGRGNVRP---FPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELL 169
L RG V+ FP + +C C I G + G WHP F C C L
Sbjct: 421 LARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAM------GRSWHPEEFTCAYCKTSL 474
Query: 170 VDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVL 229
D+ + + +YC R + + P CA C+ I E A + WH F C C+
Sbjct: 475 ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG-EVMHALRQTWHTTCFVCAACKKPF 533
Query: 230 GGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCK 289
G + M++G PYC + +L++ C C + + G WH +TCF CA C
Sbjct: 534 GNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWH--DTCFICAVCH 591
Query: 290 KSLLGRPFLPKQGQIFCSR 308
+L G+PF K+ + C +
Sbjct: 592 VNLEGQPFYSKKDRPLCKK 610
Score = 35.8 bits (81), Expect = 0.17
Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRH 186
C C + GD F GH WH CF+C VC+ L ++ + + C +H
Sbjct: 559 CHGCDFPVEAGD--KFIEALGH--TWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKH 611
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 103 bits (257), Expect = 7e-22
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 12/199 (6%)
Query: 113 LGRGNVRP---FPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELL 169
L RG V+ FP + +C C I G + G WHP F C C L
Sbjct: 531 LARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAM------GRSWHPEEFTCAYCKTSL 584
Query: 170 VDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVL 229
D+ + + +YC R + + P CA C+ I E A + WH F C C+
Sbjct: 585 ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG-EVMHALRQTWHTTCFVCAACKKPF 643
Query: 230 GGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCK 289
G + M++G PYC + +L++ C C + + G WH +TCF CA C
Sbjct: 644 GNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWH--DTCFICAVCH 701
Query: 290 KSLLGRPFLPKQGQIFCSR 308
+L G+PF K+ + C +
Sbjct: 702 VNLEGQPFYSKKDRPLCKK 720
Score = 35.8 bits (81), Expect = 0.17
Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRH 186
C C + GD F GH WH CF+C VC+ L ++ + + C +H
Sbjct: 669 CHGCDFPVEAGD--KFIEALGH--TWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKH 721
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 101 bits (251), Expect = 3e-21
Identities = 68/249 (27%), Positives = 105/249 (42%), Gaps = 14/249 (5%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFA-DECTEAEGR 213
WH CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 214 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDG 273
WH F C C+ V+G + K YC C E+ +A++C C + I G +TY
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178
Query: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC--------SRACSAGEDPNGSDSSDSA 325
Q WHA CF C C K L G+ F + Q +C ++ C+ ++P + S
Sbjct: 179 QPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSR 236
Query: 326 FQNARAKESRRSAKIGKNKGKTEEPMLNQHSQLQVSSNRLSADVDPLSLQMDMLSLSSQT 385
+ +K + GK T P N + + V L + L+ + +
Sbjct: 237 VSHPVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLA-APRG 295
Query: 386 PSLNRDPIW 394
P L + P+W
Sbjct: 296 PGLVKAPVW 304
Score = 73.9 bits (180), Expect = 6e-13
Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 220 FCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHAT 279
F C C L G++Y+ K+G C CF+ A C C + IG D ++ Y + WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH-- 62
Query: 280 ETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGED 315
+TCF CA C L F+ K +I C++ C+ ED
Sbjct: 63 DTCFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97
Score = 70.1 bits (170), Expect = 8e-12
Identities = 38/133 (28%), Positives = 56/133 (42%), Gaps = 5/133 (3%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C+ C I GD V G WH CF C+ C +++ +F + YC H
Sbjct: 101 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156
Query: 190 CLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFES 249
C C++ I + T + + WH F C C L GQR+ E + YC C+++
Sbjct: 157 KFAKHCVKCNKAITSGGIT-YQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 250 LYAEYCDTCAQHI 262
A+ C C I
Sbjct: 216 FVAKKCAGCKNPI 228
Score = 63.9 bits (154), Expect = 6e-10
Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADEC-TEAEGRHWHMK 218
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278
F C +C L + ++ K+ + C C + C C + I + Y G WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+ CF C++CK+ + F PK +C
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 31.2 bits (69), Expect = 4.2
Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 8/54 (14%)
Query: 283 FCCAHCKKSLLGRPFLPKQGQI--------FCSRACSAGEDPNGSDSSDSAFQN 328
F C +C+ L G+ ++ K G FC+ C P G+DS + ++N
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKN 58
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 100 bits (248), Expect = 7e-21
Identities = 52/153 (33%), Positives = 72/153 (47%), Gaps = 5/153 (3%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFA-DECTEAEGR 213
WH CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 214 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDG 273
WH F C C+ V+G + K YC C E+ +A++C C + I G +TY
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178
Query: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
Q WHA CF C C K L G+ F + Q +C
Sbjct: 179 QPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 96.3 bits (238), Expect = 1e-19
Identities = 54/180 (30%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C+ C I GD V G WH CF C+ C +++ +F + YC H
Sbjct: 101 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156
Query: 190 CLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFES 249
C C++ I + T + + WH F C C L GQR+ E + YC C+++
Sbjct: 157 KFAKHCVKCNKAITSGGITYQD-QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 250 LYAEYCDTCAQHI-GIDQGQ--MTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
A+ C C I G +G + Y+GQ WH + CF C C +L + F+ Q Q++C
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 73.9 bits (180), Expect = 6e-13
Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 220 FCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHAT 279
F C C L G++Y+ K+G C CF+ A C C + IG D ++ Y + WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH-- 62
Query: 280 ETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGED 315
+TCF CA C L F+ K +I C++ C+ ED
Sbjct: 63 DTCFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97
Score = 63.9 bits (154), Expect = 6e-10
Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADEC-TEAEGRHWHMK 218
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278
F C +C L + ++ K+ + C C + C C + I + Y G WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+ CF C++CK+ + F PK +C
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 57.8 bits (138), Expect = 4e-08
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 10/125 (8%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C +C I G I WH CFVC C++ L + + + YC +
Sbjct: 162 CVKCNKAITSGGITY------QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 190 CLKPRCAACDEIIFA----DECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCH 245
+ +CA C I EG+ WH F C +C L +R++ + + YC
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
Query: 246 CFESL 250
C + L
Sbjct: 276 CAKKL 280
Score = 31.2 bits (69), Expect = 4.2
Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 8/54 (14%)
Query: 283 FCCAHCKKSLLGRPFLPKQGQI--------FCSRACSAGEDPNGSDSSDSAFQN 328
F C +C+ L G+ ++ K G FC+ C P G+DS + ++N
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKN 58
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 100 bits (248), Expect = 7e-21
Identities = 52/153 (33%), Positives = 72/153 (47%), Gaps = 5/153 (3%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFA-DECTEAEGR 213
WH CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 214 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDG 273
WH F C C+ V+G + K YC C E+ +A++C C + I G +TY
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178
Query: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
Q WHA CF C C K L G+ F + Q +C
Sbjct: 179 QPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 96.3 bits (238), Expect = 1e-19
Identities = 54/180 (30%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C+ C I GD V G WH CF C+ C +++ +F + YC H
Sbjct: 101 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156
Query: 190 CLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFES 249
C C++ I + T + + WH F C C L GQR+ E + YC C+++
Sbjct: 157 KFAKHCVKCNKAITSGGITYQD-QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 250 LYAEYCDTCAQHI-GIDQGQ--MTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
A+ C C I G +G + Y+GQ WH + CF C C +L + F+ Q Q++C
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 73.9 bits (180), Expect = 6e-13
Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 220 FCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHAT 279
F C C L G++Y+ K+G C CF+ A C C + IG D ++ Y + WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH-- 62
Query: 280 ETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGED 315
+TCF CA C L F+ K +I C++ C+ ED
Sbjct: 63 DTCFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97
Score = 63.9 bits (154), Expect = 6e-10
Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADEC-TEAEGRHWHMK 218
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278
F C +C L + ++ K+ + C C + C C + I + Y G WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+ CF C++CK+ + F PK +C
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 57.8 bits (138), Expect = 4e-08
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 10/125 (8%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C +C I G I WH CFVC C++ L + + + YC +
Sbjct: 162 CVKCNKAITSGGITY------QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 190 CLKPRCAACDEIIFA----DECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCH 245
+ +CA C I EG+ WH F C +C L +R++ + + YC
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
Query: 246 CFESL 250
C + L
Sbjct: 276 CAKKL 280
Score = 31.2 bits (69), Expect = 4.2
Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 8/54 (14%)
Query: 283 FCCAHCKKSLLGRPFLPKQGQI--------FCSRACSAGEDPNGSDSSDSAFQN 328
F C +C+ L G+ ++ K G FC+ C P G+DS + ++N
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKN 58
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 100 bits (248), Expect = 7e-21
Identities = 52/153 (33%), Positives = 72/153 (47%), Gaps = 5/153 (3%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFA-DECTEAEGR 213
WH CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 90 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 149
Query: 214 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDG 273
WH F C C+ V+G + K YC C E+ +A++C C + I G +TY
Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 207
Query: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
Q WHA CF C C K L G+ F + Q +C
Sbjct: 208 QPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYC 238
Score = 96.3 bits (238), Expect = 1e-19
Identities = 54/180 (30%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C+ C I GD V G WH CF C+ C +++ +F + YC H
Sbjct: 130 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 185
Query: 190 CLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFES 249
C C++ I + T + + WH F C C L GQR+ E + YC C+++
Sbjct: 186 KFAKHCVKCNKAITSGGITYQD-QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 244
Query: 250 LYAEYCDTCAQHI-GIDQGQ--MTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
A+ C C I G +G + Y+GQ WH + CF C C +L + F+ Q Q++C
Sbjct: 245 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 302
Score = 73.9 bits (180), Expect = 6e-13
Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 220 FCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHAT 279
F C C L G++Y+ K+G C CF+ A C C + IG D ++ Y + WH
Sbjct: 34 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH-- 91
Query: 280 ETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGED 315
+TCF CA C L F+ K +I C++ C+ ED
Sbjct: 92 DTCFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 126
Score = 63.9 bits (154), Expect = 6e-10
Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADEC-TEAEGRHWHMK 218
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 34 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93
Query: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278
F C +C L + ++ K+ + C C + C C + I + Y G WH
Sbjct: 94 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 152
Query: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+ CF C++CK+ + F PK +C
Sbjct: 153 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 179
Score = 57.8 bits (138), Expect = 4e-08
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 10/125 (8%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C +C I G I WH CFVC C++ L + + + YC +
Sbjct: 191 CVKCNKAITSGGITY------QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 244
Query: 190 CLKPRCAACDEIIFA----DECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCH 245
+ +CA C I EG+ WH F C +C L +R++ + + YC
Sbjct: 245 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 304
Query: 246 CFESL 250
C + L
Sbjct: 305 CAKKL 309
Score = 31.2 bits (69), Expect = 4.2
Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 8/54 (14%)
Query: 283 FCCAHCKKSLLGRPFLPKQGQI--------FCSRACSAGEDPNGSDSSDSAFQN 328
F C +C+ L G+ ++ K G FC+ C P G+DS + ++N
Sbjct: 34 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKN 87
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 100 bits (248), Expect = 7e-21
Identities = 52/153 (33%), Positives = 72/153 (47%), Gaps = 5/153 (3%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFA-DECTEAEGR 213
WH CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
Query: 214 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDG 273
WH F C C+ V+G + K YC C E+ +A++C C + I G +TY
Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 194
Query: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
Q WHA CF C C K L G+ F + Q +C
Sbjct: 195 QPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYC 225
Score = 96.3 bits (238), Expect = 1e-19
Identities = 54/180 (30%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C+ C I GD V G WH CF C+ C +++ +F + YC H
Sbjct: 117 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 172
Query: 190 CLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFES 249
C C++ I + T + + WH F C C L GQR+ E + YC C+++
Sbjct: 173 KFAKHCVKCNKAITSGGITYQD-QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 231
Query: 250 LYAEYCDTCAQHI-GIDQGQ--MTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
A+ C C I G +G + Y+GQ WH + CF C C +L + F+ Q Q++C
Sbjct: 232 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 289
Score = 73.9 bits (180), Expect = 6e-13
Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 220 FCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHAT 279
F C C L G++Y+ K+G C CF+ A C C + IG D ++ Y + WH
Sbjct: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH-- 78
Query: 280 ETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGED 315
+TCF CA C L F+ K +I C++ C+ ED
Sbjct: 79 DTCFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 113
Score = 63.9 bits (154), Expect = 6e-10
Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADEC-TEAEGRHWHMK 218
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
Query: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278
F C +C L + ++ K+ + C C + C C + I + Y G WH
Sbjct: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 139
Query: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+ CF C++CK+ + F PK +C
Sbjct: 140 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 166
Score = 57.8 bits (138), Expect = 4e-08
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 10/125 (8%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C +C I G I WH CFVC C++ L + + + YC +
Sbjct: 178 CVKCNKAITSGGITY------QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 231
Query: 190 CLKPRCAACDEIIFA----DECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCH 245
+ +CA C I EG+ WH F C +C L +R++ + + YC
Sbjct: 232 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 291
Query: 246 CFESL 250
C + L
Sbjct: 292 CAKKL 296
Score = 31.2 bits (69), Expect = 4.2
Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 8/54 (14%)
Query: 283 FCCAHCKKSLLGRPFLPKQGQI--------FCSRACSAGEDPNGSDSSDSAFQN 328
F C +C+ L G+ ++ K G FC+ C P G+DS + ++N
Sbjct: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKN 74
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 100 bits (248), Expect = 7e-21
Identities = 52/153 (33%), Positives = 72/153 (47%), Gaps = 5/153 (3%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFA-DECTEAEGR 213
WH CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 214 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDG 273
WH F C C+ V+G + K YC C E+ +A++C C + I G +TY
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178
Query: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
Q WHA CF C C K L G+ F + Q +C
Sbjct: 179 QPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 96.3 bits (238), Expect = 1e-19
Identities = 54/180 (30%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C+ C I GD V G WH CF C+ C +++ +F + YC H
Sbjct: 101 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156
Query: 190 CLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFES 249
C C++ I + T + + WH F C C L GQR+ E + YC C+++
Sbjct: 157 KFAKHCVKCNKAITSGGITYQD-QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 250 LYAEYCDTCAQHI-GIDQGQ--MTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
A+ C C I G +G + Y+GQ WH + CF C C +L + F+ Q Q++C
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 73.9 bits (180), Expect = 6e-13
Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 220 FCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHAT 279
F C C L G++Y+ K+G C CF+ A C C + IG D ++ Y + WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH-- 62
Query: 280 ETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGED 315
+TCF CA C L F+ K +I C++ C+ ED
Sbjct: 63 DTCFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97
Score = 63.9 bits (154), Expect = 6e-10
Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADEC-TEAEGRHWHMK 218
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278
F C +C L + ++ K+ + C C + C C + I + Y G WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+ CF C++CK+ + F PK +C
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 57.8 bits (138), Expect = 4e-08
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 10/125 (8%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C +C I G I WH CFVC C++ L + + + YC +
Sbjct: 162 CVKCNKAITSGGITY------QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 190 CLKPRCAACDEIIFA----DECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCH 245
+ +CA C I EG+ WH F C +C L +R++ + + YC
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
Query: 246 CFESL 250
C + L
Sbjct: 276 CAKKL 280
Score = 31.2 bits (69), Expect = 4.2
Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 8/54 (14%)
Query: 283 FCCAHCKKSLLGRPFLPKQGQI--------FCSRACSAGEDPNGSDSSDSAFQN 328
F C +C+ L G+ ++ K G FC+ C P G+DS + ++N
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKN 58
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 100 bits (248), Expect = 7e-21
Identities = 58/183 (31%), Positives = 78/183 (42%), Gaps = 11/183 (6%)
Query: 124 TMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYC 183
T +C C I G + G WHP FVC C+ L +F +DG +C
Sbjct: 222 TQAKGLCGSCNKPIAGQVVTAL------GRAWHPEHFVCGGCSTALGGSSFFEKDGAPFC 275
Query: 184 GRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYC 243
+ E PRC C++ I + A G HWH +HFCC C G + + +EGRPYC
Sbjct: 276 PECYFERFSPRCGFCNQPI-RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC 334
Query: 244 CHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQ 303
F L+A C C I +D ++ WH CF C C G F +G+
Sbjct: 335 RRDFLQLFAPRCQGCQGPI-LD-NYISALSALWH--PDCFVCRECFAPFSGGSFFEHEGR 390
Query: 304 IFC 306
C
Sbjct: 391 PLC 393
Score = 79.3 bits (194), Expect = 1e-14
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Query: 192 KPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLY 251
K C +C++ I A + A GR WH +HF C C T LGG + K+G P+C C+ +
Sbjct: 225 KGLCGSCNKPI-AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 283
Query: 252 AEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSR 308
+ C C Q I +T G HWH FCC C + F ++G+ +C R
Sbjct: 284 SPRCGFCNQ--PIRHKMVTALGTHWHPEH--FCCVSCGEPFGDEGFHEREGRPYCRR 336
Score = 76.3 bits (186), Expect = 1e-13
Identities = 45/155 (29%), Positives = 63/155 (40%), Gaps = 5/155 (3%)
Query: 152 GVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAE 211
G WHP F C C E D + ++G+ YC R + PRC C I D A
Sbjct: 303 GTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL-DNYISAL 361
Query: 212 GRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTY 271
WH F C EC G + EGRP C + F + C TC + + ++
Sbjct: 362 SALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG--LPVTGRCVSA 419
Query: 272 DGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
G+ +H F C C + L F + G+ +C
Sbjct: 420 LGRRFHPDH--FTCTFCLRPLTKGSFQERAGKPYC 452
Score = 66.6 bits (161), Expect = 9e-11
Identities = 42/148 (28%), Positives = 58/148 (39%), Gaps = 7/148 (4%)
Query: 104 FSSQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCT 163
F + E GR R + + C+ C G I I+ ++ WHP CFVC
Sbjct: 320 FGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSA------LWHPDCFVCR 373
Query: 164 VCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCF 223
C +F +G+ C H CA C + C A GR +H HF C
Sbjct: 374 ECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG-LPVTGRCVSALGRRFHPDHFTCT 432
Query: 224 ECETVLGGQRYIMKEGRPYCCHCFESLY 251
C L + + G+PYC CF L+
Sbjct: 433 FCLRPLTKGSFQERAGKPYCQPCFLKLF 460
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 100 bits (248), Expect = 7e-21
Identities = 58/183 (31%), Positives = 78/183 (42%), Gaps = 11/183 (6%)
Query: 124 TMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYC 183
T +C C I G + G WHP FVC C+ L +F +DG +C
Sbjct: 205 TQAKGLCGSCNKPIAGQVVTAL------GRAWHPEHFVCGGCSTALGGSSFFEKDGAPFC 258
Query: 184 GRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYC 243
+ E PRC C++ I + A G HWH +HFCC C G + + +EGRPYC
Sbjct: 259 PECYFERFSPRCGFCNQPI-RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC 317
Query: 244 CHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQ 303
F L+A C C I +D ++ WH CF C C G F +G+
Sbjct: 318 RRDFLQLFAPRCQGCQGPI-LD-NYISALSALWH--PDCFVCRECFAPFSGGSFFEHEGR 373
Query: 304 IFC 306
C
Sbjct: 374 PLC 376
Score = 79.3 bits (194), Expect = 1e-14
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Query: 192 KPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLY 251
K C +C++ I A + A GR WH +HF C C T LGG + K+G P+C C+ +
Sbjct: 208 KGLCGSCNKPI-AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 266
Query: 252 AEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSR 308
+ C C Q I +T G HWH FCC C + F ++G+ +C R
Sbjct: 267 SPRCGFCNQ--PIRHKMVTALGTHWHPEH--FCCVSCGEPFGDEGFHEREGRPYCRR 319
Score = 76.3 bits (186), Expect = 1e-13
Identities = 45/155 (29%), Positives = 63/155 (40%), Gaps = 5/155 (3%)
Query: 152 GVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAE 211
G WHP F C C E D + ++G+ YC R + PRC C I D A
Sbjct: 286 GTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL-DNYISAL 344
Query: 212 GRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTY 271
WH F C EC G + EGRP C + F + C TC + + ++
Sbjct: 345 SALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG--LPVTGRCVSA 402
Query: 272 DGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
G+ +H F C C + L F + G+ +C
Sbjct: 403 LGRRFHPDH--FTCTFCLRPLTKGSFQERAGKPYC 435
Score = 66.6 bits (161), Expect = 9e-11
Identities = 42/148 (28%), Positives = 58/148 (39%), Gaps = 7/148 (4%)
Query: 104 FSSQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCT 163
F + E GR R + + C+ C G I I+ ++ WHP CFVC
Sbjct: 303 FGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSA------LWHPDCFVCR 356
Query: 164 VCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCF 223
C +F +G+ C H CA C + C A GR +H HF C
Sbjct: 357 ECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG-LPVTGRCVSALGRRFHPDHFTCT 415
Query: 224 ECETVLGGQRYIMKEGRPYCCHCFESLY 251
C L + + G+PYC CF L+
Sbjct: 416 FCLRPLTKGSFQERAGKPYCQPCFLKLF 443
>gi|30410801 activator of cAMP-responsive element modulator (CREM)
in testis [Homo sapiens]
Length = 284
Score = 100 bits (248), Expect = 7e-21
Identities = 56/178 (31%), Positives = 80/178 (44%), Gaps = 9/178 (5%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
CE+C I D + H WH CF CT CN LV+ + +D ++ C ++
Sbjct: 41 CEECKKPIES-DSKDLCYKDRH---WHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSN 96
Query: 190 CLKPRCAACDEIIF-ADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFE 248
+C C I E +G +WH F C C +G + I KE YC CFE
Sbjct: 97 ECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFE 156
Query: 249 SLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+A YC+ C + I G +T+ Q WH + CF C+ C+K L F+ + FC
Sbjct: 157 KEFAHYCNFCKK--VITSGGITFCDQLWH--KECFLCSGCRKDLCEEQFMSRDDYPFC 210
Score = 85.9 bits (211), Expect = 1e-16
Identities = 47/166 (28%), Positives = 77/166 (46%), Gaps = 6/166 (3%)
Query: 152 GVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAE 211
G WH CFVC C + + ++ YC + C C ++I + T +
Sbjct: 120 GNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCD 179
Query: 212 GRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQ--M 269
+ WH + F C C L ++++ ++ P+C C+ LYA C C++ I G +
Sbjct: 180 -QLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFI 238
Query: 270 TYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGED 315
+ WH+ CF C C SL+G+ FL + +IFC + C +G D
Sbjct: 239 CFQDSQWHS--ECFNCGKCSVSLVGKGFLTQNKEIFCQK-CGSGMD 281
Score = 83.2 bits (204), Expect = 9e-16
Identities = 33/93 (35%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
Query: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278
HF C C L G++Y++K+ PYC C++ +++ YC+ C + I D + Y +HWH
Sbjct: 5 HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWH- 63
Query: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFCSRACS 311
E CF C C SL+ +PF K ++ C+ S
Sbjct: 64 -EGCFKCTKCNHSLVEKPFAAKDERLLCTECYS 95
Score = 75.1 bits (183), Expect = 3e-13
Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 3/148 (2%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEA-EGRHWHMK 218
F C C L+ Y +D YC + C C + I +D + RHWH
Sbjct: 6 FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
Query: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278
F C +C L + + K+ R C C+ + + C C + I +M + G +WH
Sbjct: 66 CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH- 124
Query: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC 306
ETCF C +C++ + +P + K+ +C
Sbjct: 125 -ETCFVCENCRQPIGTKPLISKESGNYC 151
Score = 30.8 bits (68), Expect = 5.5
Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 8/58 (13%)
Query: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC--------SRACSAGEDPNGSDSSDSAFQN 328
T F C +C SLLG+ ++ K +C S C + P SDS D +++
Sbjct: 2 TTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKD 59
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 97.8 bits (242), Expect = 4e-20
Identities = 54/184 (29%), Positives = 85/184 (46%), Gaps = 9/184 (4%)
Query: 124 TMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYC 183
T+ CE+CG I G D + + H WH CF C+ C LVD + ++ ++ C
Sbjct: 34 TLFANTCEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLC 89
Query: 184 GRHHAECLKPRCAACDEIIF-ADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPY 242
++ +C C + I E +G WH F C C+ +G + +I K+ + +
Sbjct: 90 TDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNF 149
Query: 243 CCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQG 302
C C+E +A C C + I G +TY Q WH + CF C C+K L G+ F +
Sbjct: 150 CVPCYEKQHAMQCVQCKK--PITTGGVTYREQPWH--KECFVCTACRKQLSGQRFTARDD 205
Query: 303 QIFC 306
+C
Sbjct: 206 FAYC 209
Score = 92.0 bits (227), Expect = 2e-18
Identities = 37/90 (41%), Positives = 56/90 (62%), Gaps = 2/90 (2%)
Query: 218 KHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWH 277
+ F C C L G++YI++E PYC CFE+L+A C+ C + IG D ++Y +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 278 ATETCFCCAHCKKSLLGRPFLPKQGQIFCS 307
E CF C+ C+ SL+ +PF K+ Q+ C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 90.5 bits (223), Expect = 6e-18
Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 152 GVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAE 211
G WH CF+C C + + + +D + +C + + +C C + I T E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 212 GRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQG--QM 269
+ WH + F C C L GQR+ ++ YC +CF LYA+ C C I G +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237
Query: 270 TYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+++ + WH CF C C SL+GR FL ++ I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 87.4 bits (215), Expect = 5e-17
Identities = 51/160 (31%), Positives = 69/160 (43%), Gaps = 27/160 (16%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEA--------- 210
F C CNE L GK Y R + P C C E +FA+ C E
Sbjct: 5 FDCHHCNESLF--------GKKYILREES----PYCVVCFETLFANTCEECGKPIGCDCK 52
Query: 211 ----EGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQ 266
+ RHWH F C +C L + + KE + C C+ + Y+ C C + I
Sbjct: 53 DLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGT 112
Query: 267 GQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+M Y G WH ETCF C C++ + + F+PK Q FC
Sbjct: 113 RKMEYKGSSWH--ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 51.2 bits (121), Expect = 4e-06
Identities = 33/120 (27%), Positives = 45/120 (37%), Gaps = 9/120 (7%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C QC I G + WH CFVCT C + L + +D YC +
Sbjct: 162 CVQCKKPITTGGVTYREQP------WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 190 CLKPRCAACDEIIFADECTEA---EGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHC 246
+CA C I T+ E R WH F C +C L G+ ++ + C C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 97.8 bits (242), Expect = 4e-20
Identities = 54/184 (29%), Positives = 85/184 (46%), Gaps = 9/184 (4%)
Query: 124 TMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYC 183
T+ CE+CG I G D + + H WH CF C+ C LVD + ++ ++ C
Sbjct: 34 TLFANTCEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLC 89
Query: 184 GRHHAECLKPRCAACDEIIF-ADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPY 242
++ +C C + I E +G WH F C C+ +G + +I K+ + +
Sbjct: 90 TDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNF 149
Query: 243 CCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQG 302
C C+E +A C C + I G +TY Q WH + CF C C+K L G+ F +
Sbjct: 150 CVPCYEKQHAMQCVQCKK--PITTGGVTYREQPWH--KECFVCTACRKQLSGQRFTARDD 205
Query: 303 QIFC 306
+C
Sbjct: 206 FAYC 209
Score = 92.0 bits (227), Expect = 2e-18
Identities = 37/90 (41%), Positives = 56/90 (62%), Gaps = 2/90 (2%)
Query: 218 KHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWH 277
+ F C C L G++YI++E PYC CFE+L+A C+ C + IG D ++Y +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 278 ATETCFCCAHCKKSLLGRPFLPKQGQIFCS 307
E CF C+ C+ SL+ +PF K+ Q+ C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 90.5 bits (223), Expect = 6e-18
Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 152 GVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAE 211
G WH CF+C C + + + +D + +C + + +C C + I T E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 212 GRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQG--QM 269
+ WH + F C C L GQR+ ++ YC +CF LYA+ C C I G +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237
Query: 270 TYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+++ + WH CF C C SL+GR FL ++ I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 87.4 bits (215), Expect = 5e-17
Identities = 51/160 (31%), Positives = 69/160 (43%), Gaps = 27/160 (16%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEA--------- 210
F C CNE L GK Y R + P C C E +FA+ C E
Sbjct: 5 FDCHHCNESLF--------GKKYILREES----PYCVVCFETLFANTCEECGKPIGCDCK 52
Query: 211 ----EGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQ 266
+ RHWH F C +C L + + KE + C C+ + Y+ C C + I
Sbjct: 53 DLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGT 112
Query: 267 GQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+M Y G WH ETCF C C++ + + F+PK Q FC
Sbjct: 113 RKMEYKGSSWH--ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 51.2 bits (121), Expect = 4e-06
Identities = 33/120 (27%), Positives = 45/120 (37%), Gaps = 9/120 (7%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C QC I G + WH CFVCT C + L + +D YC +
Sbjct: 162 CVQCKKPITTGGVTYREQP------WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 190 CLKPRCAACDEIIFADECTEA---EGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHC 246
+CA C I T+ E R WH F C +C L G+ ++ + C C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 97.8 bits (242), Expect = 4e-20
Identities = 54/184 (29%), Positives = 85/184 (46%), Gaps = 9/184 (4%)
Query: 124 TMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYC 183
T+ CE+CG I G D + + H WH CF C+ C LVD + ++ ++ C
Sbjct: 34 TLFANTCEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLC 89
Query: 184 GRHHAECLKPRCAACDEIIF-ADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPY 242
++ +C C + I E +G WH F C C+ +G + +I K+ + +
Sbjct: 90 TDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNF 149
Query: 243 CCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQG 302
C C+E +A C C + I G +TY Q WH + CF C C+K L G+ F +
Sbjct: 150 CVPCYEKQHAMQCVQCKK--PITTGGVTYREQPWH--KECFVCTACRKQLSGQRFTARDD 205
Query: 303 QIFC 306
+C
Sbjct: 206 FAYC 209
Score = 92.0 bits (227), Expect = 2e-18
Identities = 37/90 (41%), Positives = 56/90 (62%), Gaps = 2/90 (2%)
Query: 218 KHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWH 277
+ F C C L G++YI++E PYC CFE+L+A C+ C + IG D ++Y +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 278 ATETCFCCAHCKKSLLGRPFLPKQGQIFCS 307
E CF C+ C+ SL+ +PF K+ Q+ C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 90.5 bits (223), Expect = 6e-18
Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 152 GVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAE 211
G WH CF+C C + + + +D + +C + + +C C + I T E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 212 GRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQG--QM 269
+ WH + F C C L GQR+ ++ YC +CF LYA+ C C I G +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237
Query: 270 TYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+++ + WH CF C C SL+GR FL ++ I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 87.4 bits (215), Expect = 5e-17
Identities = 51/160 (31%), Positives = 69/160 (43%), Gaps = 27/160 (16%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEA--------- 210
F C CNE L GK Y R + P C C E +FA+ C E
Sbjct: 5 FDCHHCNESLF--------GKKYILREES----PYCVVCFETLFANTCEECGKPIGCDCK 52
Query: 211 ----EGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQ 266
+ RHWH F C +C L + + KE + C C+ + Y+ C C + I
Sbjct: 53 DLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGT 112
Query: 267 GQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+M Y G WH ETCF C C++ + + F+PK Q FC
Sbjct: 113 RKMEYKGSSWH--ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 51.2 bits (121), Expect = 4e-06
Identities = 33/120 (27%), Positives = 45/120 (37%), Gaps = 9/120 (7%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C QC I G + WH CFVCT C + L + +D YC +
Sbjct: 162 CVQCKKPITTGGVTYREQP------WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 190 CLKPRCAACDEIIFADECTEA---EGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHC 246
+CA C I T+ E R WH F C +C L G+ ++ + C C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 97.8 bits (242), Expect = 4e-20
Identities = 54/184 (29%), Positives = 85/184 (46%), Gaps = 9/184 (4%)
Query: 124 TMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYC 183
T+ CE+CG I G D + + H WH CF C+ C LVD + ++ ++ C
Sbjct: 34 TLFANTCEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLC 89
Query: 184 GRHHAECLKPRCAACDEIIF-ADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPY 242
++ +C C + I E +G WH F C C+ +G + +I K+ + +
Sbjct: 90 TDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNF 149
Query: 243 CCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQG 302
C C+E +A C C + I G +TY Q WH + CF C C+K L G+ F +
Sbjct: 150 CVPCYEKQHAMQCVQCKK--PITTGGVTYREQPWH--KECFVCTACRKQLSGQRFTARDD 205
Query: 303 QIFC 306
+C
Sbjct: 206 FAYC 209
Score = 92.0 bits (227), Expect = 2e-18
Identities = 37/90 (41%), Positives = 56/90 (62%), Gaps = 2/90 (2%)
Query: 218 KHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWH 277
+ F C C L G++YI++E PYC CFE+L+A C+ C + IG D ++Y +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 278 ATETCFCCAHCKKSLLGRPFLPKQGQIFCS 307
E CF C+ C+ SL+ +PF K+ Q+ C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 90.5 bits (223), Expect = 6e-18
Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 152 GVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAE 211
G WH CF+C C + + + +D + +C + + +C C + I T E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 212 GRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQG--QM 269
+ WH + F C C L GQR+ ++ YC +CF LYA+ C C I G +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237
Query: 270 TYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+++ + WH CF C C SL+GR FL ++ I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 87.4 bits (215), Expect = 5e-17
Identities = 51/160 (31%), Positives = 69/160 (43%), Gaps = 27/160 (16%)
Query: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEA--------- 210
F C CNE L GK Y R + P C C E +FA+ C E
Sbjct: 5 FDCHHCNESLF--------GKKYILREES----PYCVVCFETLFANTCEECGKPIGCDCK 52
Query: 211 ----EGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQ 266
+ RHWH F C +C L + + KE + C C+ + Y+ C C + I
Sbjct: 53 DLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGT 112
Query: 267 GQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+M Y G WH ETCF C C++ + + F+PK Q FC
Sbjct: 113 RKMEYKGSSWH--ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 51.2 bits (121), Expect = 4e-06
Identities = 33/120 (27%), Positives = 45/120 (37%), Gaps = 9/120 (7%)
Query: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
C QC I G + WH CFVCT C + L + +D YC +
Sbjct: 162 CVQCKKPITTGGVTYREQP------WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 190 CLKPRCAACDEIIFADECTEA---EGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHC 246
+CA C I T+ E R WH F C +C L G+ ++ + C C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 96.7 bits (239), Expect = 8e-20
Identities = 54/183 (29%), Positives = 80/183 (43%), Gaps = 11/183 (6%)
Query: 124 TMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYC 183
T+ +C C I G + G WHP FVCT C E + +F +DG+ YC
Sbjct: 185 TVAKGVCGACKKPIAGQVVTAM------GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 238
Query: 184 GRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYC 243
+ + PRC C+ I D+ A R WH +HF C +C G + + K+G+ YC
Sbjct: 239 EKDYHNLFSPRCYYCNGPIL-DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 297
Query: 244 CHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQ 303
+ ++A C CA+ I + ++ WH CF C C + F GQ
Sbjct: 298 RKDYFDMFAPKCGGCAR--AILENYISALNTLWH--PECFVCRECFTPFVNGSFFEHDGQ 353
Query: 304 IFC 306
+C
Sbjct: 354 PYC 356
Score = 68.9 bits (167), Expect = 2e-11
Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRH 214
WHP CFVC C V+ +F DG+ YC H+ E C+ C + I C A +
Sbjct: 328 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 386
Query: 215 WHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLY 251
+H +HF C C L + + +PYC +CF L+
Sbjct: 387 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
Score = 66.2 bits (160), Expect = 1e-10
Identities = 41/153 (26%), Positives = 61/153 (39%), Gaps = 7/153 (4%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRH 214
WHP F C C + +DGK YC + + + P+C C I + A
Sbjct: 269 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL-ENYISALNTL 327
Query: 215 WHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQ-MTYDG 273
WH + F C EC T + +G+PYC + C C + I G+ +T
Sbjct: 328 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI---TGRCITAMA 384
Query: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+ +H F CA C K L F + + +C
Sbjct: 385 KKFHPEH--FVCAFCLKQLNKGTFKEQNDKPYC 415
Score = 62.8 bits (151), Expect = 1e-09
Identities = 36/121 (29%), Positives = 57/121 (47%), Gaps = 5/121 (4%)
Query: 188 AECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCF 247
A K C AC + I A + A G+ WH +HF C C+ +G + + ++G+PYC +
Sbjct: 184 ATVAKGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 242
Query: 248 ESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCS 307
+L++ C C I +D+ D + WH F CA C F K G+ +C
Sbjct: 243 HNLFSPRCYYCNGPI-LDKVVTALD-RTWHPEH--FFCAQCGAFFGPEGFHEKDGKAYCR 298
Query: 308 R 308
+
Sbjct: 299 K 299
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 96.7 bits (239), Expect = 8e-20
Identities = 54/183 (29%), Positives = 80/183 (43%), Gaps = 11/183 (6%)
Query: 124 TMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYC 183
T+ +C C I G + G WHP FVCT C E + +F +DG+ YC
Sbjct: 318 TVAKGVCGACKKPIAGQVVTAM------GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 371
Query: 184 GRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYC 243
+ + PRC C+ I D+ A R WH +HF C +C G + + K+G+ YC
Sbjct: 372 EKDYHNLFSPRCYYCNGPIL-DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 430
Query: 244 CHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQ 303
+ ++A C CA+ I + ++ WH CF C C + F GQ
Sbjct: 431 RKDYFDMFAPKCGGCAR--AILENYISALNTLWH--PECFVCRECFTPFVNGSFFEHDGQ 486
Query: 304 IFC 306
+C
Sbjct: 487 PYC 489
Score = 68.9 bits (167), Expect = 2e-11
Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRH 214
WHP CFVC C V+ +F DG+ YC H+ E C+ C + I C A +
Sbjct: 461 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 519
Query: 215 WHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLY 251
+H +HF C C L + + +PYC +CF L+
Sbjct: 520 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
Score = 66.2 bits (160), Expect = 1e-10
Identities = 41/153 (26%), Positives = 61/153 (39%), Gaps = 7/153 (4%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRH 214
WHP F C C + +DGK YC + + + P+C C I + A
Sbjct: 402 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL-ENYISALNTL 460
Query: 215 WHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQ-MTYDG 273
WH + F C EC T + +G+PYC + C C + I G+ +T
Sbjct: 461 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI---TGRCITAMA 517
Query: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+ +H F CA C K L F + + +C
Sbjct: 518 KKFHPEH--FVCAFCLKQLNKGTFKEQNDKPYC 548
Score = 62.8 bits (151), Expect = 1e-09
Identities = 36/121 (29%), Positives = 57/121 (47%), Gaps = 5/121 (4%)
Query: 188 AECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCF 247
A K C AC + I A + A G+ WH +HF C C+ +G + + ++G+PYC +
Sbjct: 317 ATVAKGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 375
Query: 248 ESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCS 307
+L++ C C I +D+ D + WH F CA C F K G+ +C
Sbjct: 376 HNLFSPRCYYCNGPI-LDKVVTALD-RTWHPEH--FFCAQCGAFFGPEGFHEKDGKAYCR 431
Query: 308 R 308
+
Sbjct: 432 K 432
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 96.7 bits (239), Expect = 8e-20
Identities = 54/183 (29%), Positives = 80/183 (43%), Gaps = 11/183 (6%)
Query: 124 TMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYC 183
T+ +C C I G + G WHP FVCT C E + +F +DG+ YC
Sbjct: 352 TVAKGVCGACKKPIAGQVVTAM------GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 405
Query: 184 GRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYC 243
+ + PRC C+ I D+ A R WH +HF C +C G + + K+G+ YC
Sbjct: 406 EKDYHNLFSPRCYYCNGPIL-DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 464
Query: 244 CHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQ 303
+ ++A C CA+ I + ++ WH CF C C + F GQ
Sbjct: 465 RKDYFDMFAPKCGGCAR--AILENYISALNTLWH--PECFVCRECFTPFVNGSFFEHDGQ 520
Query: 304 IFC 306
+C
Sbjct: 521 PYC 523
Score = 68.9 bits (167), Expect = 2e-11
Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRH 214
WHP CFVC C V+ +F DG+ YC H+ E C+ C + I C A +
Sbjct: 495 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 553
Query: 215 WHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLY 251
+H +HF C C L + + +PYC +CF L+
Sbjct: 554 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
Score = 66.2 bits (160), Expect = 1e-10
Identities = 41/153 (26%), Positives = 61/153 (39%), Gaps = 7/153 (4%)
Query: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRH 214
WHP F C C + +DGK YC + + + P+C C I + A
Sbjct: 436 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL-ENYISALNTL 494
Query: 215 WHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQ-MTYDG 273
WH + F C EC T + +G+PYC + C C + I G+ +T
Sbjct: 495 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI---TGRCITAMA 551
Query: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
+ +H F CA C K L F + + +C
Sbjct: 552 KKFHPEH--FVCAFCLKQLNKGTFKEQNDKPYC 582
Score = 62.8 bits (151), Expect = 1e-09
Identities = 36/121 (29%), Positives = 57/121 (47%), Gaps = 5/121 (4%)
Query: 188 AECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCF 247
A K C AC + I A + A G+ WH +HF C C+ +G + + ++G+PYC +
Sbjct: 351 ATVAKGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 409
Query: 248 ESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCS 307
+L++ C C I +D+ D + WH F CA C F K G+ +C
Sbjct: 410 HNLFSPRCYYCNGPI-LDKVVTALD-RTWHPEH--FFCAQCGAFFGPEGFHEKDGKAYCR 465
Query: 308 R 308
+
Sbjct: 466 K 466
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 94.0 bits (232), Expect = 5e-19
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 9/178 (5%)
Query: 129 ICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHA 188
+C QC I G + G +HP FVC+ C ++L + +F + G I+C +
Sbjct: 247 VCHQCHKVIRGRYLVAL------GHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYD 300
Query: 189 ECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFE 248
P CA C + I E A WH+ F C C+T + + + M+EG PYC +E
Sbjct: 301 VRYAPSCAKCKKKI-TGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYE 359
Query: 249 SLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC 306
++ C C I + G WH +TCF CA C+ +L G+ F K+ + C
Sbjct: 360 KMFGTKCHGCDFKIDAGDRFLEALGFSWH--DTCFVCAICQINLEGKTFYSKKDRPLC 415
Score = 56.6 bits (135), Expect = 9e-08
Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 7/117 (5%)
Query: 193 PRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYA 252
P C C ++I A G +H + F C +C VL + ++G +C C++ YA
Sbjct: 246 PVCHQCHKVI-RGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 304
Query: 253 EYCDTCAQHIGIDQGQMTYD-GQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSR 308
C C + I G++ + WH CF CA CK + R F ++G +C R
Sbjct: 305 PSCAKCKKKI---TGEIMHALKMTWHVH--CFTCAACKTPIRNRAFYMEEGVPYCER 356
Score = 37.0 bits (84), Expect = 0.077
Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 4/62 (6%)
Query: 125 MTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCG 184
M G C C +I+ GD + A G WH CFVC +C L ++ + + C
Sbjct: 361 MFGTKCHGCDFKIDAGDRFLEAL----GFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 416
Query: 185 RH 186
H
Sbjct: 417 SH 418
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,059,672
Number of Sequences: 37866
Number of extensions: 1828057
Number of successful extensions: 7817
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 213
Number of HSP's that attempted gapping in prelim test: 6502
Number of HSP's gapped (non-prelim): 953
length of query: 844
length of database: 18,247,518
effective HSP length: 111
effective length of query: 733
effective length of database: 14,044,392
effective search space: 10294539336
effective search space used: 10294539336
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.