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Search of human proteins with 38045915
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38045915 pregnancy-associated plasma protein A preproprotein
[Homo sapiens]
(1627 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38045915 pregnancy-associated plasma protein A preproprotein ... 3468 0.0
gi|116174738 pappalysin 2 isoform 1 [Homo sapiens] 1498 0.0
gi|116174734 pappalysin 2 isoform 2 [Homo sapiens] 585 e-166
gi|157419154 selectin P precursor [Homo sapiens] 93 2e-18
gi|187960042 selectin E precursor [Homo sapiens] 92 4e-18
gi|148886654 polydom [Homo sapiens] 83 2e-15
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 82 6e-15
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 78 6e-14
gi|7657619 sushi-repeat-containing protein, X-linked 2 [Homo sap... 74 1e-12
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 70 1e-11
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 70 1e-11
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 70 1e-11
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 70 2e-11
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 70 2e-11
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 64 1e-09
gi|4502503 complement component 4 binding protein, alpha chain p... 62 3e-09
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 62 5e-09
gi|168693643 decay accelerating factor for complement isoform 2 ... 60 1e-08
gi|10835143 decay accelerating factor for complement isoform 1 p... 60 1e-08
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 59 4e-08
gi|110611237 coagulation factor XIII B subunit precursor [Homo s... 59 5e-08
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 58 9e-08
gi|5454086 sushi-repeat-containing protein, X-linked [Homo sapiens] 57 1e-07
gi|118442839 complement factor H-related 1 [Homo sapiens] 56 2e-07
gi|239758113 PREDICTED: similar to complement factor H-related 1... 56 2e-07
gi|62739188 complement factor H isoform b precursor [Homo sapiens] 55 6e-07
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 55 7e-07
gi|5031695 H factor (complement)-like 3 [Homo sapiens] 52 5e-06
gi|4506875 selectin L precursor [Homo sapiens] 52 6e-06
gi|14550407 complement component 2 isoform 1 preproprotein [Homo... 50 2e-05
>gi|38045915 pregnancy-associated plasma protein A preproprotein [Homo
sapiens]
Length = 1627
Score = 3468 bits (8993), Expect = 0.0
Identities = 1627/1627 (100%), Positives = 1627/1627 (100%)
Query: 1 MRLWSWVLHLGLLSAALGCGLAERPRRARRDPRAGRPPRPAAGPATCATRAARGRRASPP 60
MRLWSWVLHLGLLSAALGCGLAERPRRARRDPRAGRPPRPAAGPATCATRAARGRRASPP
Sbjct: 1 MRLWSWVLHLGLLSAALGCGLAERPRRARRDPRAGRPPRPAAGPATCATRAARGRRASPP 60
Query: 61 PPPPPGGAWEAVRVPRRRQQREARGATEEPSPPSRALYFSGRGEQLRLRADLELPRDAFT 120
PPPPPGGAWEAVRVPRRRQQREARGATEEPSPPSRALYFSGRGEQLRLRADLELPRDAFT
Sbjct: 61 PPPPPGGAWEAVRVPRRRQQREARGATEEPSPPSRALYFSGRGEQLRLRADLELPRDAFT 120
Query: 121 LQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWVVGIHTISDQDNKDPRYFFSLKTDRAR 180
LQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWVVGIHTISDQDNKDPRYFFSLKTDRAR
Sbjct: 121 LQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWVVGIHTISDQDNKDPRYFFSLKTDRAR 180
Query: 181 QVTTINAHRSYLPGQWVYLAATYDGQFMKLYVNGAQVATSGEQVGGIFSPLTQKCKVLML 240
QVTTINAHRSYLPGQWVYLAATYDGQFMKLYVNGAQVATSGEQVGGIFSPLTQKCKVLML
Sbjct: 181 QVTTINAHRSYLPGQWVYLAATYDGQFMKLYVNGAQVATSGEQVGGIFSPLTQKCKVLML 240
Query: 241 GGSALNHNYRGYIEHFSLWKVARTQREILSDMETHGAHTALPQLLLQENWDNVKHAWSPM 300
GGSALNHNYRGYIEHFSLWKVARTQREILSDMETHGAHTALPQLLLQENWDNVKHAWSPM
Sbjct: 241 GGSALNHNYRGYIEHFSLWKVARTQREILSDMETHGAHTALPQLLLQENWDNVKHAWSPM 300
Query: 301 KDGSSPKVEFSNAHGFLLDTSLEPPLCGQTLCDNTEVIASYNQLSSFRQPKVVRYRVVNL 360
KDGSSPKVEFSNAHGFLLDTSLEPPLCGQTLCDNTEVIASYNQLSSFRQPKVVRYRVVNL
Sbjct: 301 KDGSSPKVEFSNAHGFLLDTSLEPPLCGQTLCDNTEVIASYNQLSSFRQPKVVRYRVVNL 360
Query: 361 YEDDHKNPTVTREQVDFQHHQLAEAFKQYNISWELDVLEVSNSSLRRRLILANCDISKIG 420
YEDDHKNPTVTREQVDFQHHQLAEAFKQYNISWELDVLEVSNSSLRRRLILANCDISKIG
Sbjct: 361 YEDDHKNPTVTREQVDFQHHQLAEAFKQYNISWELDVLEVSNSSLRRRLILANCDISKIG 420
Query: 421 DENCDPECNHTLTGHDGGDCRHLRHPAFVKKQHNGVCDMDCNYERFNFDGGECCDPEITN 480
DENCDPECNHTLTGHDGGDCRHLRHPAFVKKQHNGVCDMDCNYERFNFDGGECCDPEITN
Sbjct: 421 DENCDPECNHTLTGHDGGDCRHLRHPAFVKKQHNGVCDMDCNYERFNFDGGECCDPEITN 480
Query: 481 VTQTCFDPDSPHRAYLDVNELKNILKLDGSTHLNIFFAKSSEEELAGVATWPWDKEALMH 540
VTQTCFDPDSPHRAYLDVNELKNILKLDGSTHLNIFFAKSSEEELAGVATWPWDKEALMH
Sbjct: 481 VTQTCFDPDSPHRAYLDVNELKNILKLDGSTHLNIFFAKSSEEELAGVATWPWDKEALMH 540
Query: 541 LGGIVLNPSFYGMPGHTHTMIHEIGHSLGLYHVFRGISEIQSCSDPCMETEPSFETGDLC 600
LGGIVLNPSFYGMPGHTHTMIHEIGHSLGLYHVFRGISEIQSCSDPCMETEPSFETGDLC
Sbjct: 541 LGGIVLNPSFYGMPGHTHTMIHEIGHSLGLYHVFRGISEIQSCSDPCMETEPSFETGDLC 600
Query: 601 NDTNPAPKHKSCGDPGPGNDTCGFHSFFNTPYNNFMSYADDDCTDSFTPNQVARMHCYLD 660
NDTNPAPKHKSCGDPGPGNDTCGFHSFFNTPYNNFMSYADDDCTDSFTPNQVARMHCYLD
Sbjct: 601 NDTNPAPKHKSCGDPGPGNDTCGFHSFFNTPYNNFMSYADDDCTDSFTPNQVARMHCYLD 660
Query: 661 LVYQGWQPSRKPAPVALAPQVLGHTTDSVTLEWFPPIDGHFFERELGSACHLCLEGRILV 720
LVYQGWQPSRKPAPVALAPQVLGHTTDSVTLEWFPPIDGHFFERELGSACHLCLEGRILV
Sbjct: 661 LVYQGWQPSRKPAPVALAPQVLGHTTDSVTLEWFPPIDGHFFERELGSACHLCLEGRILV 720
Query: 721 QYASNASSPMPCSPSGHWSPREAEGHPDVEQPCKSSVRTWSPNSAVNPHTVPPACPEPQG 780
QYASNASSPMPCSPSGHWSPREAEGHPDVEQPCKSSVRTWSPNSAVNPHTVPPACPEPQG
Sbjct: 721 QYASNASSPMPCSPSGHWSPREAEGHPDVEQPCKSSVRTWSPNSAVNPHTVPPACPEPQG 780
Query: 781 CYLELEFLYPLVPESLTIWVTFVSTDWDSSGAVNDIKLLAVSGKNISLGPQNVFCDVPLT 840
CYLELEFLYPLVPESLTIWVTFVSTDWDSSGAVNDIKLLAVSGKNISLGPQNVFCDVPLT
Sbjct: 781 CYLELEFLYPLVPESLTIWVTFVSTDWDSSGAVNDIKLLAVSGKNISLGPQNVFCDVPLT 840
Query: 841 IRLWDVGEEVYGIQIYTLDEHLEIDAAMLTSTADTPLCLQCKPLKYKVVRDPPLQMDVAS 900
IRLWDVGEEVYGIQIYTLDEHLEIDAAMLTSTADTPLCLQCKPLKYKVVRDPPLQMDVAS
Sbjct: 841 IRLWDVGEEVYGIQIYTLDEHLEIDAAMLTSTADTPLCLQCKPLKYKVVRDPPLQMDVAS 900
Query: 901 ILHLNRKFVDMDLNLGSVYQYWVITISGTEESEPSPAVTYIHGSGYCGDGIIQKDQGEQC 960
ILHLNRKFVDMDLNLGSVYQYWVITISGTEESEPSPAVTYIHGSGYCGDGIIQKDQGEQC
Sbjct: 901 ILHLNRKFVDMDLNLGSVYQYWVITISGTEESEPSPAVTYIHGSGYCGDGIIQKDQGEQC 960
Query: 961 DDMNKINGDGCSLFCRQEVSFNCIDEPSRCYFHDGDGVCEEFEQKTSIKDCGVYTPQGFL 1020
DDMNKINGDGCSLFCRQEVSFNCIDEPSRCYFHDGDGVCEEFEQKTSIKDCGVYTPQGFL
Sbjct: 961 DDMNKINGDGCSLFCRQEVSFNCIDEPSRCYFHDGDGVCEEFEQKTSIKDCGVYTPQGFL 1020
Query: 1021 DQWASNASVSHQDQQCPGWVIIGQPAASQVCRTKVIDLSEGISQHAWYPCTISYPYSQLA 1080
DQWASNASVSHQDQQCPGWVIIGQPAASQVCRTKVIDLSEGISQHAWYPCTISYPYSQLA
Sbjct: 1021 DQWASNASVSHQDQQCPGWVIIGQPAASQVCRTKVIDLSEGISQHAWYPCTISYPYSQLA 1080
Query: 1081 QTTFWLRAYFSQPMVAAAVIVHLVTDGTYYGDQKQETISVQLLDTKDQSHDLGLHVLSCR 1140
QTTFWLRAYFSQPMVAAAVIVHLVTDGTYYGDQKQETISVQLLDTKDQSHDLGLHVLSCR
Sbjct: 1081 QTTFWLRAYFSQPMVAAAVIVHLVTDGTYYGDQKQETISVQLLDTKDQSHDLGLHVLSCR 1140
Query: 1141 NNPLIIPVVHDLSQPFYHSQAVRVSFSSPLVAISGVALRSFDNFDPVTLSSCQRGETYSP 1200
NNPLIIPVVHDLSQPFYHSQAVRVSFSSPLVAISGVALRSFDNFDPVTLSSCQRGETYSP
Sbjct: 1141 NNPLIIPVVHDLSQPFYHSQAVRVSFSSPLVAISGVALRSFDNFDPVTLSSCQRGETYSP 1200
Query: 1201 AEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQ 1260
AEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQ
Sbjct: 1201 AEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQ 1260
Query: 1261 TGPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQL 1320
TGPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQL
Sbjct: 1261 TGPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQL 1320
Query: 1321 KGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPG 1380
KGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPG
Sbjct: 1321 KGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPG 1380
Query: 1381 YHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRI 1440
YHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRI
Sbjct: 1381 YHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRI 1440
Query: 1441 KCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGS 1500
KCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGS
Sbjct: 1441 KCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGS 1500
Query: 1501 ECATSCLDHNSESIILPMNVTVRDIPHWLNPTRVERVVCTAGLKWYPHPALIHCVKGCEP 1560
ECATSCLDHNSESIILPMNVTVRDIPHWLNPTRVERVVCTAGLKWYPHPALIHCVKGCEP
Sbjct: 1501 ECATSCLDHNSESIILPMNVTVRDIPHWLNPTRVERVVCTAGLKWYPHPALIHCVKGCEP 1560
Query: 1561 FMGDNYCDAINNRAFCNYDGGDCCTSTVKTKKVTPFPMSCDLQGDCACRDPQAQEHSRKD 1620
FMGDNYCDAINNRAFCNYDGGDCCTSTVKTKKVTPFPMSCDLQGDCACRDPQAQEHSRKD
Sbjct: 1561 FMGDNYCDAINNRAFCNYDGGDCCTSTVKTKKVTPFPMSCDLQGDCACRDPQAQEHSRKD 1620
Query: 1621 LRGYSHG 1627
LRGYSHG
Sbjct: 1621 LRGYSHG 1627
>gi|116174738 pappalysin 2 isoform 1 [Homo sapiens]
Length = 1791
Score = 1498 bits (3878), Expect = 0.0
Identities = 712/1546 (46%), Positives = 1008/1546 (65%), Gaps = 44/1546 (2%)
Query: 97 LYFSGRGEQLRLRADL--ELPRDAFTLQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWV 154
LYFSGR E+L LR ++ E+PR+AFT++ W++ EGGQ +PA+I G++D CS+ D+GW
Sbjct: 263 LYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQNNPAIIAGVFDNCSHTVSDKGWA 322
Query: 155 VGIHTISDQDNKDPRYFFSLKTDRARQVTTINAHRSYLPGQWVYLAATYDGQFMKLYVNG 214
+GI + D+ +D R+FFSL TDR ++ T + +H Y PG W ++AATYDG+ M LYV+G
Sbjct: 323 LGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQPGTWTHVAATYDGRHMALYVDG 382
Query: 215 AQVATSGEQVGGIFSPLTQKCKVLMLGGSALN--HNYRGYIEHFSLWKVARTQREILSDM 272
QVA+S +Q G + SP C+ L+LGG + H +RG++ W A Q
Sbjct: 383 TQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFRGHLGTLVFWSTALPQSHFQHSS 442
Query: 273 ETHGAHTALPQLLLQENWDNVKHAWSPMKDGSSPKVEFSNAHGFLLD----TSLEPPLCG 328
+ L+L +++ V W P +D P++E GF + + L+PPLCG
Sbjct: 443 QHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEV--LQGFEPEPEILSPLQPPLCG 500
Query: 329 QTLCDNTEVIASYNQLSSFRQPKVVRYRVVNLYEDDHKNPTVTREQVDFQHHQLAEAFKQ 388
QT+CDN E+I+ YN R KV+RY+VVN+ +D+ NP V+ EQ+ QH L EAF +
Sbjct: 501 QTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNPIVSEEQIRLQHEALNEAFSR 560
Query: 389 YNISWELDVLEVSNSSLRRRLILANCDISKIGDENCDPECNHTLTGHDGGDCRHLRHPAF 448
YNISW+L V +V NS+LR R++L NC+ SKIG+++CDPEC H LTG+DGGDCR L+ +
Sbjct: 561 YNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGYDGGDCR-LQGRCY 619
Query: 449 VKKQHNGVCDMDCNYERFNFDGGECCDPEITNVTQTCFDPDSPHRAYLDVNELKNILKLD 508
+ +G+C ++CN +FD G+CCDP++ +V +TCFDPDSP RAY+ V ELK L+L+
Sbjct: 620 SWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPDSPKRAYMSVKELKEALQLN 679
Query: 509 GSTHLNIFFAKSSEEELAGVATWPWDKEALMHLGGIVLNPSFYGMPGHTHTMIHEIGHSL 568
+ LNI+FA S E+LAG ATWPWDK+A+ HLGGIVL+P++YGMPGHT TMIHE+GH L
Sbjct: 680 STHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPAYYGMPGHTDTMIHEVGHVL 739
Query: 569 GLYHVFRGISEIQSCSDPCMETEPSFETGDLCNDTNPAPKHKSCGDPGPGNDTCGFHSFF 628
GLYHVF+G+SE +SC+DPC ET PS ETGDLC DT P PK + C +P P +DTCGF F
Sbjct: 740 GLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKSELCREPEPTSDTCGFTRFP 799
Query: 629 NTPYNNFMSYADDDCTDSFTPNQVARMHCYLDLVYQGWQPSRKPAPVALAPQVLGHTTDS 688
P+ N+MSY DD+CTD+FTPNQVARMHCYLDLVYQ W SRKP P+ + P V+G T S
Sbjct: 800 GAPFTNYMSYTDDNCTDNFTPNQVARMHCYLDLVYQQWTESRKPTPIPIPPMVIGQTNKS 859
Query: 689 VTLEWFPPIDGHFFERELGSACHLCLEGRILVQYASNASSPMPCSPSGHWSPREAEGHPD 748
+T+ W PPI G ++R GS C C E QY ASS C SG+W+P EA G PD
Sbjct: 860 LTIHWLPPISGVVYDRASGSLCGACTEDGTFRQYVHTASSRRVCDSSGYWTPEEAVGPPD 919
Query: 749 VEQPCKSSVRTWSPNSAVNPHTVPPACPEPQGCYLELEFLYPLVPESLTIWVTFVSTDWD 808
V+QPC+ S++ WSP + + CP +GC LEL F +P+ ++LT+WVT S +
Sbjct: 920 VDQPCEPSLQAWSPEVHLYHMNMTVPCP-TEGCSLELLFQHPVQADTLTLWVT--SFFME 976
Query: 809 SSGAVNDIKLLAVSGKNISLGPQNVFCDVPLTIRLWDVGEEVYGIQIYTLDEHLEIDAAM 868
SS + D ++L + +++ LGP + FCD+PLTI+L V +V G+++YT DE +EIDAA+
Sbjct: 977 SSQVLFDTEILLENKESVHLGPLDTFCDIPLTIKL-HVDGKVSGVKVYTFDERIEIDAAL 1035
Query: 869 LTSTADTPLCLQCKPLKYKVVRDPPLQMDVASIL-HLNRKFVDMDLNLGSVYQYWVITIS 927
LTS +PLC C+P++Y+V+RDPP + ++ H +RKF D+++ G +YQY V+ +
Sbjct: 1036 LTSQPHSPLCSGCRPVRYQVLRDPPFASGLPVVVTHSHRKFTDVEVTPGQMYQYQVLAEA 1095
Query: 928 GTEESEPSPAVTYIHGSGYCGDGIIQKDQGEQCDDMNKINGDGCSLFCRQEVSFNCIDEP 987
G E E SP + +IHG+ YCGDG + + GE+CDD + ++GDGCS C E FNC+ EP
Sbjct: 1096 GGELGEASPPLNHIHGAPYCGDGKVSERLGEECDDGDLVSGDGCSKVCELEEGFNCVGEP 1155
Query: 988 SRCYFHDGDGVCEEFEQKTSIKDCGVYTPQGFLDQWASNASVSHQD-QQCPGWVIIGQPA 1046
S CY ++GDG+CE FE+KTSI DCG+YTP+G+LDQWA+ A SH+D ++CP ++ G+P
Sbjct: 1156 SLCYMYEGDGICEPFERKTSIVDCGIYTPKGYLDQWATRAYSSHEDKKKCPVSLVTGEP- 1214
Query: 1047 ASQVCRTKVIDLSEGISQHAWYPCTISYPYSQ-----------LAQTTFWLRAYFSQPMV 1095
S +C + DL W+PC S +Q + WL+ F++P
Sbjct: 1215 HSLICTSYHPDLPNHRPLTGWFPCVASENETQDDRSEQPEGSLKKEDEVWLKVCFNRPGE 1274
Query: 1096 AAAVIVHLVTDGTYYGDQKQETISVQLLDTKDQSHDLGLHVLSCRNNPLIIPVVHDLSQP 1155
A A+ + L TDG G+ +Q T+++ L D + +H LG + LSC++NPLII V H +
Sbjct: 1275 ARAIFIFLTTDGLVPGEHQQPTVTLYLTDVRGSNHSLGTYGLSCQHNPLIINVTHHQNVL 1334
Query: 1156 FYHSQAVRVSFSSPLVAISGVALRSFDNFDPVTLSSC-QRGETYSPAEQSCVHFACEKTD 1214
F+H+ +V ++FSSP V IS VALR+ S+C E + QSC+H C K D
Sbjct: 1335 FHHTTSVLLNFSSPRVGISAVALRTSSRIGLSAPSNCISEDEGQNHQGQSCIHRPCGKQD 1394
Query: 1215 -CPELAVENAS-LNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEG 1272
CP L +++A +NC+S +C ++C+ G+ LQ + Q + +TC+ G
Sbjct: 1395 SCPSLLLDHADVVNCTSIGP-GLMKCAITCQRGFALQASSGQYIRPMQ--KEILLTCSSG 1451
Query: 1273 KWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMED 1332
W++ V+C PVDC +PD V A+FSC EGT F +CS C PA+L+G + LTC+ED
Sbjct: 1452 HWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLED 1511
Query: 1333 GLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSR-KSK 1391
GLWS PE C+L C APP + NA+L C ++ H VG+ CKY+CKPGY+V S+ K +
Sbjct: 1512 GLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVR 1571
Query: 1392 KRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGL 1451
+ K QC + G W++G+C+PV C+PPPP F G+Y+CTNGF +S+C + C +Q
Sbjct: 1572 NKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNC-----NQER 1626
Query: 1452 GSNVIHCRKDGTWNGSFHVCQEMQGQC-SVPNELNSNLKLQCPDGYAIGSECATSCLDHN 1510
I C K+G W F +C+ +QG+C P+ELNS ++ +C GY IG+ C+ C+
Sbjct: 1627 EKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS-VEYKCEQGYGIGAVCSPLCVIPP 1685
Query: 1511 SESIILPMNVTVRDIPHWLNPTRVERVVCTAGLKWYPHPALIHCVKGCEPFMGDNYCDAI 1570
S+ ++LP N+T + HW+ P +V+ +VCT +W+P P L+HC++ CEPF D +CD I
Sbjct: 1686 SDPVMLPENITADTLEHWMEPVKVQSIVCTGRRQWHPDPVLVHCIQSCEPFQADGWCDTI 1745
Query: 1571 NNRAFCNYDGGDCCTSTVKTKKVTPFPMSCDLQGDCACRDPQAQEH 1616
NNRA+C+YDGGDCC+ST+ +KKV PF CDL +C CRDP+A+E+
Sbjct: 1746 NNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLD-ECTCRDPKAEEN 1790
>gi|116174734 pappalysin 2 isoform 2 [Homo sapiens]
Length = 827
Score = 585 bits (1507), Expect = e-166
Identities = 273/550 (49%), Positives = 376/550 (68%), Gaps = 11/550 (2%)
Query: 97 LYFSGRGEQLRLRADL--ELPRDAFTLQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWV 154
LYFSGR E+L LR ++ E+PR+AFT++ W++ EGGQ +PA+I G++D CS+ D+GW
Sbjct: 263 LYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQNNPAIIAGVFDNCSHTVSDKGWA 322
Query: 155 VGIHTISDQDNKDPRYFFSLKTDRARQVTTINAHRSYLPGQWVYLAATYDGQFMKLYVNG 214
+GI + D+ +D R+FFSL TDR ++ T + +H Y PG W ++AATYDG+ M LYV+G
Sbjct: 323 LGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQPGTWTHVAATYDGRHMALYVDG 382
Query: 215 AQVATSGEQVGGIFSPLTQKCKVLMLGGSALN--HNYRGYIEHFSLWKVARTQREILSDM 272
QVA+S +Q G + SP C+ L+LGG + H +RG++ W A Q
Sbjct: 383 TQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFRGHLGTLVFWSTALPQSHFQHSS 442
Query: 273 ETHGAHTALPQLLLQENWDNVKHAWSPMKDGSSPKVEFSNAHGFLLD----TSLEPPLCG 328
+ L+L +++ V W P +D P++E GF + + L+PPLCG
Sbjct: 443 QHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEV--LQGFEPEPEILSPLQPPLCG 500
Query: 329 QTLCDNTEVIASYNQLSSFRQPKVVRYRVVNLYEDDHKNPTVTREQVDFQHHQLAEAFKQ 388
QT+CDN E+I+ YN R KV+RY+VVN+ +D+ NP V+ EQ+ QH L EAF +
Sbjct: 501 QTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNPIVSEEQIRLQHEALNEAFSR 560
Query: 389 YNISWELDVLEVSNSSLRRRLILANCDISKIGDENCDPECNHTLTGHDGGDCRHLRHPAF 448
YNISW+L V +V NS+LR R++L NC+ SKIG+++CDPEC H LTG+DGGDCR L+ +
Sbjct: 561 YNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGYDGGDCR-LQGRCY 619
Query: 449 VKKQHNGVCDMDCNYERFNFDGGECCDPEITNVTQTCFDPDSPHRAYLDVNELKNILKLD 508
+ +G+C ++CN +FD G+CCDP++ +V +TCFDPDSP RAY+ V ELK L+L+
Sbjct: 620 SWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPDSPKRAYMSVKELKEALQLN 679
Query: 509 GSTHLNIFFAKSSEEELAGVATWPWDKEALMHLGGIVLNPSFYGMPGHTHTMIHEIGHSL 568
+ LNI+FA S E+LAG ATWPWDK+A+ HLGGIVL+P++YGMPGHT TMIHE+GH L
Sbjct: 680 STHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPAYYGMPGHTDTMIHEVGHVL 739
Query: 569 GLYHVFRGISEIQSCSDPCMETEPSFETGDLCNDTNPAPKHKSCGDPGPGNDTCGFHSFF 628
GLYHVF+G+SE +SC+DPC ET PS ETGDLC DT P PK + C +P P +DTCGF F
Sbjct: 740 GLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKSELCREPEPTSDTCGFTRFP 799
Query: 629 NTPYNNFMSY 638
P+ N+MSY
Sbjct: 800 GAPFTNYMSY 809
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 92.8 bits (229), Expect = 2e-18
Identities = 72/287 (25%), Positives = 111/287 (38%), Gaps = 38/287 (13%)
Query: 1214 DCPELAV-ENASLNCSS--SDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCT 1270
+C EL + ++ +NCS + +QC+ C GY + GPS
Sbjct: 199 ECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVN------------GPSKLECLA 246
Query: 1271 EGKW-NKQVACEPVDC---SIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSL 1326
G W NK C C IP+ + + S CSF C L G +
Sbjct: 247 SGIWTNKPPQCLAAQCPPLKIPERGNM--TCLHSAKAFQHQSSCSFSCEEGFALVGPE-V 303
Query: 1327 LTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGS 1386
+ C G+W+ P +C+ + P+ GS CK++C+PGY V G
Sbjct: 304 VQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGL 363
Query: 1387 SRKSKKRAFKTQCTQDGSWQE--GACVPVTCDPPPPKFHGLYQCT---NGFQFNSECRIK 1441
+C G W C ++C+P HG C+ FQ+++ C +
Sbjct: 364 D--------MLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFR 415
Query: 1442 CEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQ-CSVPNELNSN 1487
C + + G++++ C G W VCQ +Q Q VPNE N
Sbjct: 416 CAEGFMLR--GADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVN 460
Score = 74.7 bits (182), Expect = 7e-13
Identities = 82/327 (25%), Positives = 122/327 (37%), Gaps = 61/327 (18%)
Query: 1210 CEKTDCPELAVEN-ASLNCS---SSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSV 1265
C+ C +L V N A +NCS + RY C+ +C G +L G SV
Sbjct: 443 CQALQCQDLPVPNEARVNCSHPFGAFRYQSV-CSFTCNEGLLL------------VGASV 489
Query: 1266 TVTCTEGKWNK-QVACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKGN 1323
G WN C+ + C+ Q + P G++ + S C F C L G
Sbjct: 490 LQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGP 549
Query: 1324 NSLLTCMEDGLWSFPEALCE-LMC--LAPPPVPNADLQTARCRENKHKVGSFCKYKCKPG 1380
L C G W+ +CE + C L P + D R N VGS C + C G
Sbjct: 550 ERL-DCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFN---VGSTCHFSCDNG 605
Query: 1381 YHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDP----PPPKFH---------GLYQ 1427
+ + G + +CT G W + P TC P P G
Sbjct: 606 FKLEGPNN--------VECTTSGRW---SATPPTCKGIASLPTPGVQCPALTTPGQGTMY 654
Query: 1428 CTNG---FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNEL 1484
C + F FN+ C C +G + + CR G W C+ + +CS +
Sbjct: 655 CRHHPGTFGFNTTCYFGCNAGFTL--IGDSTLSCRPSGQWTAVTPACRAV--KCS-ELHV 709
Query: 1485 NSNLKLQCPD---GYAIGSECATSCLD 1508
N + + C + ++ GS C+ CL+
Sbjct: 710 NKPIAMNCSNLWGNFSYGSICSFHCLE 736
Score = 70.5 bits (171), Expect = 1e-11
Identities = 70/302 (23%), Positives = 112/302 (37%), Gaps = 50/302 (16%)
Query: 1204 SCVHFACEKTDCPELAVENASLNCSSSDR--YHGAQCTVSCRTGYVLQIRRDDELIKSQT 1261
+C +CE + P + S++CS S R + C+ C G++L+
Sbjct: 380 TCEAISCEPLESPV----HGSMDCSPSLRAFQYDTNCSFRCAEGFMLR------------ 423
Query: 1262 GPSVTVTCTEGKWNKQV-ACEPVDCS---IPDHHQVYAASFSCPEGT-TFGSQCSFQCRH 1316
G + G+W C+ + C +P+ +V + S P G + S CSF C
Sbjct: 424 GADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARV---NCSHPFGAFRYQSVCSFTCNE 480
Query: 1317 PAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYK 1376
L G S+L C+ G W+ C+ + P P T S C++
Sbjct: 481 GLLLVGA-SVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFI 539
Query: 1377 CKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEG--ACVPVTCDPPPPKFHGLYQCTN---G 1431
C GY + G R CT+ G W + C + C G C++
Sbjct: 540 CDEGYSLSGPER--------LDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGE 591
Query: 1432 FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQ 1491
F S C C++ + G N + C G W+ + C +G S+P +Q
Sbjct: 592 FNVGSTCHFSCDNGFKLE--GPNNVECTTSGRWSATPPTC---KGIASLPTP-----GVQ 641
Query: 1492 CP 1493
CP
Sbjct: 642 CP 643
Score = 66.6 bits (161), Expect = 2e-10
Identities = 74/330 (22%), Positives = 116/330 (35%), Gaps = 45/330 (13%)
Query: 1163 RVSFSSPLVAISGVALRSFDNFDPVTLSSCQRGETYSPAEQSCVHFACEKTDC-PELAVE 1221
RV+ S P A ++ SF + + L + + + V C+ C P L+ +
Sbjct: 458 RVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQ 517
Query: 1222 NASLNCSS--SDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKW-NKQV 1278
N ++ C + + C C GY L +GP G+W +
Sbjct: 518 NGTMTCVQPLGSSSYKSTCQFICDEGYSL------------SGPERLDCTRSGRWTDSPP 565
Query: 1279 ACEPVDCSIPDHHQVYAASFSCPEGT---TFGSQCSFQCRHPAQLKGNNSLLTCMEDGLW 1335
CE + C P+ S C + GS C F C + +L+G N++ C G W
Sbjct: 566 MCEAIKC--PELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNV-ECTTSGRW 622
Query: 1336 SFPEALCELMCLAPPP------VPNADLQTARCRENKHKVG--SFCKYKCKPGYHVPGSS 1387
S C+ + P P + T CR + G + C + C G+ + G S
Sbjct: 623 SATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDS 682
Query: 1388 RKSKKRAFKTQCTQDGSWQE--GACVPVTCDPPPPKFHGLYQCTN---GFQFNSECRIKC 1442
S C G W AC V C C+N F + S C C
Sbjct: 683 TLS--------CRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHC 734
Query: 1443 EDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
+ G C+++G W+ + CQ
Sbjct: 735 LEGQLLNGSAQTA--CQENGHWSTTVPTCQ 762
Score = 60.5 bits (145), Expect = 1e-08
Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 34/175 (19%)
Query: 1367 HKVGSF-----CKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPP 1419
H +G+F C + C GY V G S K +C G W + C+ C P
Sbjct: 215 HPLGNFSFNSQCSFHCTDGYQVNGPS--------KLECLASGIWTNKPPQCLAAQCPPLK 266
Query: 1420 PKFHGLYQCTNG---FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQG 1476
G C + FQ S C CE+ A +G V+ C G W VC+ +Q
Sbjct: 267 IPERGNMTCLHSAKAFQHQSSCSFSCEEGFAL--VGPEVVQCTASGVWTAPAPVCKAVQC 324
Query: 1477 Q-CSVPNE-------------LNSNLKLQCPDGYAIGSECATSCLDHNSESIILP 1517
Q P+E S+ K +C GY + C+D S LP
Sbjct: 325 QHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLP 379
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 92.0 bits (227), Expect = 4e-18
Identities = 90/355 (25%), Positives = 136/355 (38%), Gaps = 53/355 (14%)
Query: 1190 SSCQRGETYSPAEQSCVHFACEKTDCPELA-VENASLNCSSSDRYH--GAQCTVSCRTGY 1246
SS + + S E S AC +C + N + C + CT C G+
Sbjct: 217 SSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGF 276
Query: 1247 VLQIRRDDELIKSQTGPSVTVTCTE-GKW-NKQVACEPVDCSIPDHHQVYAASFS-CPEG 1303
EL+ +Q+ + CT G W N++ C+ V C Q + S P G
Sbjct: 277 --------ELMGAQS-----LQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAG 323
Query: 1304 T-TFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCE-LMCLAPPPVPNADLQTAR 1361
TF S C+F C L+G + + C G W+ +CE C A +
Sbjct: 324 EFTFKSSCNFTCEEGFMLQGP-AQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLP 382
Query: 1362 CRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDP-- 1417
+ GS C++ C+ G+ + GS R QC G W ++ C V CD
Sbjct: 383 SASGSFRYGSSCEFSCEQGFVLKGSKR--------LQCGPTGEWDNEKPTCEAVRCDAVH 434
Query: 1418 PPPKFHGLYQCTNG----FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQE 1473
PPK GL +C + F + S C CE+ GS + C G W CQ
Sbjct: 435 QPPK--GLVRCAHSPIGEFTYKSSCAFSCEEGFELH--GSTQLECTSQGQWTEEVPSCQV 490
Query: 1474 MQ-GQCSVPNELNSN----------LKLQCPDGYAIGSECATSCLDHNSESIILP 1517
++ +VP ++N + K CP+G+ + A +C S +LP
Sbjct: 491 VKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLP 545
Score = 73.6 bits (179), Expect = 2e-12
Identities = 69/262 (26%), Positives = 97/262 (37%), Gaps = 41/262 (15%)
Query: 1269 CTEGKWNKQVACEP----------VDCSIPDHHQVYAASFSCPEGT-TFGSQCSFQCRHP 1317
C E N C+P V+C+ + + + S P G ++ S CS C
Sbjct: 154 CVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDR- 212
Query: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELM-CLAPPPVPNADLQTARCRENKHKVGSF---- 1372
L + + CM G WS P C ++ C A V N C +N GSF
Sbjct: 213 GYLPSSMETMQCMSSGEWSAPIPACNVVECDA---VTNPANGFVECFQNP---GSFPWNT 266
Query: 1373 -CKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGLYQCT 1429
C + C+ G+ + G A QCT G+W ++ C VTC +G +C+
Sbjct: 267 TCTFDCEEGFELMG--------AQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCS 318
Query: 1430 NG----FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQ-GQCSVPNEL 1484
+ F F S C CE+ QG + C G W VC+ Q S P
Sbjct: 319 HSPAGEFTFKSSCNFTCEEGFMLQGPAQ--VECTTQGQWTQQIPVCEAFQCTALSNPERG 376
Query: 1485 NSNLKLQCPDGYAIGSECATSC 1506
N + GS C SC
Sbjct: 377 YMNCLPSASGSFRYGSSCEFSC 398
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 82.8 bits (203), Expect = 2e-15
Identities = 75/338 (22%), Positives = 129/338 (38%), Gaps = 56/338 (16%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIR 1251
CQ T++ + SC+ C+ P EN L + + G+ SC+ G++L
Sbjct: 2699 CQEDGTWNGSAPSCISIECDLPTAP----ENGFLRFTETSM--GSAVQYSCKPGHIL--- 2749
Query: 1252 RDDELIKSQTGPSVTVTCTEGKWN-KQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQC 1310
G + + KW+ CE + C P + V S T+ S
Sbjct: 2750 ---------AGSDLRLCLENRKWSGASPRCEAISCKKP--NPVMNGSIK-GSNYTYLSTL 2797
Query: 1311 SFQCRHPAQLKGNNSLLTCMEDGLWSFPEALC-ELMCLAPPPVPNADLQTARCRENKHKV 1369
++C P + TC +D W E +C + C +PP N + R +++
Sbjct: 2798 YYEC-DPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQV-----RGDEYTF 2851
Query: 1370 GSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQ 1427
+Y C G+ + G+ + C +GSW CVPV C PP +G+ +
Sbjct: 2852 QKEIEYTCNEGFLLEGARSR--------VCLANGSWSGATPDCVPVRCATPPQLANGVTE 2903
Query: 1428 CTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNEL--- 1484
+ + F E C + G+ + C+ DG W+ +C+ + C P +L
Sbjct: 2904 GLD-YGFMKEVTFHCHEGYILH--GAPKLTCQSDGNWDAEIPLCKPV--NCGPPEDLAHG 2958
Query: 1485 ---------NSNLKLQCPDGYAIGSECATSCLDHNSES 1513
+++ QC GY + + CL + S S
Sbjct: 2959 FPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWS 2996
Score = 74.7 bits (182), Expect = 7e-13
Identities = 90/401 (22%), Positives = 142/401 (35%), Gaps = 67/401 (16%)
Query: 1148 VVHDLSQPFYHSQAVRVSFSSPLVAISGVALRSFDNFDPVTLSS-----CQRGETYSPAE 1202
+ H +P S ++ S S A V SF + L++ C RG ++P+
Sbjct: 2079 IAHFCEKPPSVSYSILESVSKAKFAAGSVV--SFKCMEGFVLNTSAKIECMRGGQWNPSP 2136
Query: 1203 QS--CVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQ 1260
S C+ C + ++ N S S+ GA SC G+ ++
Sbjct: 2137 MSIQCIPVRCGEPP----SIMNGY--ASGSNYSFGAMVAYSCNKGFYIK----------- 2179
Query: 1261 TGPSVTVTCTEGKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQ 1319
G + G+W+ + C PV C P +V G F S+ +QC +P
Sbjct: 2180 -GEKKSTCEATGQWSSPIPTCHPVSCGEPP--KVENGFLEHTTGRIFESEVRYQC-NPGY 2235
Query: 1320 LKGNNSLLTCMEDGLW--SFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKC 1377
+ + C + W P L C PPP+ N + + +VGS ++ C
Sbjct: 2236 KSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFM-----KGENFEVGSKVQFFC 2290
Query: 1378 KPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA---CVPVTCDPPPPKFHGLYQCTNGFQF 1434
GY + G S + C + G W + + C+P C P PP
Sbjct: 2291 NEGYELVGDSSWT--------CQKSGKWNKKSNPKCMPAKC-PEPPLLENQLVLKELTTE 2341
Query: 1435 NSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPN------------ 1482
C++ QG +V+ C WN SF VC+ + C+ P
Sbjct: 2342 VGVVTFSCKEGHVLQG--PSVLKCLPSQQWNDSFPVCKIV--LCTPPPLISFGVPIPSSA 2397
Query: 1483 -ELNSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTV 1522
S +K C G+ + T C + S LP V V
Sbjct: 2398 LHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV 2438
Score = 73.9 bits (180), Expect = 1e-12
Identities = 85/382 (22%), Positives = 131/382 (34%), Gaps = 59/382 (15%)
Query: 1191 SCQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQI 1250
+CQ + + E C+ DC V +A+ + + +C G++L+
Sbjct: 2814 TCQDDKNWDEDEPICI-----PVDCSSPPV-SANGQVRGDEYTFQKEIEYTCNEGFLLE- 2866
Query: 1251 RRDDELIKSQTGPSVTVTCTEGKWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTFG-- 1307
G V G W+ C PV C+ P + EG +G
Sbjct: 2867 -----------GARSRVCLANGSWSGATPDCVPVRCATPPQ-----LANGVTEGLDYGFM 2910
Query: 1308 SQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKH 1367
+ +F C H + LTC DG W LC+ + PP DL
Sbjct: 2911 KEVTFHC-HEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP----EDLAHGFPNGFSF 2965
Query: 1368 KVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGL 1425
G +Y+C PGY + G+S + +C +GSW +C+P C P +
Sbjct: 2966 IHGGHIQYQCFPGYKLHGNSSR--------RCLSNGSWSGSSPSCLPCRCSTPVIE---- 3013
Query: 1426 YQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQ--GQCSVPNE 1483
Y NG F+ + + + LG + I C DG W+ F C+ +PN
Sbjct: 3014 YGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNA 3073
Query: 1484 LNSN--------LKLQCPDGYAIGSECATSCLDHNSESIILPMNVTVRDIPHWLNPTRVE 1535
S + C GY I C + S P V + +P V
Sbjct: 3074 FISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYP----VCEPLSCGSPPSVA 3129
Query: 1536 RVVCTAGLKWYPHPALIHCVKG 1557
V T Y + C++G
Sbjct: 3130 NAVATGEAHTYESEVKLRCLEG 3151
Score = 71.6 bits (174), Expect = 6e-12
Identities = 90/412 (21%), Positives = 140/412 (33%), Gaps = 101/412 (24%)
Query: 1187 VTLSSCQRGETYSPAEQSCVHFACEKTDCPELA-VENASLNCSSSDRYHGAQCTVSCRTG 1245
VT +C ++ C +C K PE +E + G++ T C G
Sbjct: 1824 VTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFT-------FGSKVTYRCNKG 1876
Query: 1246 YVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQV-ACEPVDCSIPDH--HQVYAASFSCPE 1302
Y L G + W+ CEPV CS P++ + Y S
Sbjct: 1877 YTL------------AGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILS----- 1919
Query: 1303 GTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARC 1362
G T+ S S+ C L+G S++ C G+W C L+ PP ++ A
Sbjct: 1920 GLTYLSTASYSCDTGYSLQGP-SIIECTASGIWDRAPPACHLVFCGEPPA----IKDAVI 1974
Query: 1363 RENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEG--ACVPVTCDPPPP 1420
N + Y CK GY + G +C DG W C+ V+CD PP
Sbjct: 1975 TGNNFTFRNTVTYTCKEGYTLAGLDT--------IECLADGKWSRSDQQCLAVSCDEPPI 2026
Query: 1421 KFHG-------------LYQCTNGFQFNSECRIKCEDSDASQGL-----GSNVIHCRKDG 1462
H Y C++G+ ++ C +QG G ++ C
Sbjct: 2027 VDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCN----AQGKWVPPEGQDMPRCIA-- 2080
Query: 1463 TWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTV 1522
H C++ P+ S L+ +A GS + C+ E +L +
Sbjct: 2081 ------HFCEKP------PSVSYSILESVSKAKFAAGSVVSFKCM----EGFVLNTSA-- 2122
Query: 1523 RDIPHWLNPTRVERVVCTAGLKWYPHPALIHCVK---GCEPFMGDNYCDAIN 1571
++ C G +W P P I C+ G P + + Y N
Sbjct: 2123 -------------KIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSN 2161
Score = 70.1 bits (170), Expect = 2e-11
Identities = 57/241 (23%), Positives = 89/241 (36%), Gaps = 35/241 (14%)
Query: 1281 EPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEA 1340
EP+ C P + + S E T G++ +F C+ QL G + TC+E G W+
Sbjct: 1785 EPIKCKAPGNPE---NGHSSGEIYTVGAEVTFSCQEGYQLMGVTKI-TCLESGEWNHLIP 1840
Query: 1341 LCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCT 1400
C+ + P +P + E GS Y+C GY + G S C
Sbjct: 1841 YCKAVSCGKPAIP----ENGCIEELAFTFGSKVTYRCNKGYTLAGDKESS--------CL 1888
Query: 1401 QDGSWQEG--ACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHC 1458
+ SW C PV C P +G Y +G + S C+ + Q G ++I C
Sbjct: 1889 ANSSWSHSPPVCEPVKCSSPENINNGKY-ILSGLTYLSTASYSCDTGYSLQ--GPSIIEC 1945
Query: 1459 RKDGTWNGSFHVCQEMQGQCSVPNEL------------NSNLKLQCPDGYAIGSECATSC 1506
G W+ + C + C P + + + C +GY + C
Sbjct: 1946 TASGIWDRAPPACHLV--FCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIEC 2003
Query: 1507 L 1507
L
Sbjct: 2004 L 2004
Score = 69.3 bits (168), Expect = 3e-11
Identities = 73/271 (26%), Positives = 98/271 (36%), Gaps = 54/271 (19%)
Query: 1210 CEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTC 1269
C CPE + L G T SC+ G+VLQ GPSV
Sbjct: 2318 CMPAKCPEPPLLENQLVLKELTTEVGV-VTFSCKEGHVLQ------------GPSVLKCL 2364
Query: 1270 TEGKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTT---FGSQCSFQCRHPAQLKGNNS 1325
+WN C+ V C+ P SF P ++ FGS + C L+GN++
Sbjct: 2365 PSQQWNDSFPVCKIVLCTPPP-----LISFGVPIPSSALHFGSTVKYSCVGGFFLRGNST 2419
Query: 1326 LLTCMEDGLWSFPEALC-ELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVP 1384
L C DG WS P C + C P +PN + S Y CKPG+ +
Sbjct: 2420 TL-CQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYL-----STALYTCKPGFELV 2473
Query: 1385 GSSRKSKKRAFKTQCTQDGSWQEG--ACVPVTCDPPPPKFHG-------------LYQCT 1429
G++ T C ++G W G C + C P +G Y C
Sbjct: 2474 GNT--------TTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCN 2525
Query: 1430 NGFQFNSECRIKC-EDSDASQGLGS-NVIHC 1458
GF+ + C E D S N IHC
Sbjct: 2526 RGFRLEGPSALTCLETGDWDVDAPSCNAIHC 2556
Score = 68.9 bits (167), Expect = 4e-11
Identities = 81/384 (21%), Positives = 139/384 (36%), Gaps = 103/384 (26%)
Query: 1192 CQRGETYSPAEQSCVHFAC-EKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQI 1250
CQ T+S CV C + + P ++ L S+ Y +C+ G+ L
Sbjct: 2422 CQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALY-------TCKPGFEL-- 2472
Query: 1251 RRDDELIKSQTGPSVTVTCTEGKW-NKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQ 1309
G + T+ G W + C+ ++C P ++ FS + +G
Sbjct: 2473 ----------VGNTTTLCGENGHWLGGKPTCKAIECLKPK--EILNGKFSYTD-LHYGQT 2519
Query: 1310 CSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELM-CLAPPPVPNADLQTARCRENKHK 1368
++ C +L+G S LTC+E G W C + C +P P+ N ++ A +
Sbjct: 2520 VTYSCNRGFRLEGP-SALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGA-----DYS 2573
Query: 1369 VGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEG--ACVPVTCDPPP------- 1419
G+ Y C PG+ V G + ++ C + G W C+P+ C PP
Sbjct: 2574 YGAIIIYSCFPGFQVAGHAMQT--------CEESG-WSSSIPTCMPIDCGLPPHIDFGDC 2624
Query: 1420 -------------------------PKFH-GLYQCT------------NGFQFNSECRIK 1441
P +H G T + F + +
Sbjct: 2625 TKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYT 2684
Query: 1442 CEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVP------------NELNSNLK 1489
C + + LG+ V+ C++DGTWNGS C + +C +P + S ++
Sbjct: 2685 C--NPGYELLGNPVLICQEDGTWNGSAPSCISI--ECDLPTAPENGFLRFTETSMGSAVQ 2740
Query: 1490 LQCPDGYAIGSECATSCLDHNSES 1513
C G+ + CL++ S
Sbjct: 2741 YSCKPGHILAGSDLRLCLENRKWS 2764
Score = 68.6 bits (166), Expect = 5e-11
Identities = 76/339 (22%), Positives = 121/339 (35%), Gaps = 56/339 (16%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIR 1251
C ++S + SC+ C V +C + R + C G+ L
Sbjct: 2989 CLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTDFDCGKAAR-------IQCFKGFKL--- 3038
Query: 1252 RDDELIKSQTGPSVTVTCTEGKWNKQVA-CEPVDC-SIPDHHQVYAASFSCPEGTTFGSQ 1309
G S +G+W+ CE C S+P + + S +
Sbjct: 3039 ---------LGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVI--- 3086
Query: 1310 CSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCE-LMCLAPPPVPNADLQTARCRENKHK 1368
++ CR ++G++ L+ C E G+WS P +CE L C +PP V NA + T H
Sbjct: 3087 -TYSCRSGYVIQGSSDLI-CTEKGVWSQPYPVCEPLSCGSPPSVANA-VATGEA----HT 3139
Query: 1369 VGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGLY 1426
S K +C GY + + C +DG W + +C P C P P +
Sbjct: 3140 YESEVKLRCLEGYTMDTDTD-------TFTCQKDGRWFPERISCSPKKC-PLPENITHIL 3191
Query: 1427 QCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNE--- 1483
+ F N + + C + +G+ N+ C+ DGTW F C P
Sbjct: 3192 VHGDDFSVNRQVSVSCAEGYTFEGV--NISVCQLDGTWEPPFSDESCSPVSCGKPESPEH 3249
Query: 1484 ---------LNSNLKLQCPDGYAIGSECATSCLDHNSES 1513
S + QC GY + C ++ S
Sbjct: 3250 GFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWS 3288
Score = 68.2 bits (165), Expect = 6e-11
Identities = 87/363 (23%), Positives = 130/363 (35%), Gaps = 55/363 (15%)
Query: 1164 VSFSSPLVAISGVALRSFDNFDPVTLSSCQRGETYS-PAEQSCVHFA--------CEKTD 1214
VS P + +G F C +G T + E SC+ + CE
Sbjct: 1845 VSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVK 1904
Query: 1215 CPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKW 1274
C N S Y + SC TGY LQ GPS+ G W
Sbjct: 1905 CSSPENINNGKYILSGLTYLST-ASYSCDTGYSLQ------------GPSIIECTASGIW 1951
Query: 1275 NKQV-ACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDG 1333
++ AC V C P + TF + ++ C+ L G +++ C+ DG
Sbjct: 1952 DRAPPACHLVFCGEPP---AIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTI-ECLADG 2007
Query: 1334 LWSFPEALC-ELMCLAPPPVPNADLQTARCRENKHKV-GSFCKYKCKPGYHVPGSSRKSK 1391
WS + C + C PP V +A +TA H++ G Y C GY + +S
Sbjct: 2008 KWSRSDQQCLAVSCDEPPIVDHASPETA------HRLFGDIAFYYCSDGYSLADNS---- 2057
Query: 1392 KRAFKTQCTQDGSW--QEG----ACVPVTCDPPPPKFHGLYQCTNGFQF--NSECRIKCE 1443
+ C G W EG C+ C+ PP + + + + +F S KC
Sbjct: 2058 ----QLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCM 2113
Query: 1444 DSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSECA 1503
+ S I C + G WN S Q + +C P + + Y+ G+ A
Sbjct: 2114 EGFVLN--TSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNG--YASGSNYSFGAMVA 2169
Query: 1504 TSC 1506
SC
Sbjct: 2170 YSC 2172
Score = 67.8 bits (164), Expect = 8e-11
Identities = 87/376 (23%), Positives = 129/376 (34%), Gaps = 96/376 (25%)
Query: 1155 PFYHSQAVRVSFSSPLVAISGVALRSFDNFDPVTLSSCQRG-ETYSPAEQSCVH------ 1207
PF VS P G + S F+ + C+ G E E+ C
Sbjct: 3230 PFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSG 3289
Query: 1208 --FACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSV 1265
C++T C E +E + +R G SC GY L+ GPS
Sbjct: 3290 GVAICKETRC-ETPLEFLNGKADIENRTTGPNVVYSCNRGYSLE------------GPSE 3336
Query: 1266 TVTCTEGKWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTFGSQ-------CSFQCRHP 1317
G W+ V C+P C +P F PE + S +CR
Sbjct: 3337 AHCTENGTWSHPVPLCKPNPCPVP---------FVIPENALLSEKEFYVDQNVSIKCREG 3387
Query: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKC 1377
L+G+ ++TC D W+ A CE + PP A ++ A R ++ G Y C
Sbjct: 3388 FLLQGHG-IITCNPDETWTQTSAKCEKISCGPP----AHVENAIARGVHYQYGDMITYSC 3442
Query: 1378 KPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSE 1437
GY + G R + C ++G+W P C +
Sbjct: 3443 YSGYMLEGFLR--------SVCLENGTWTS----PPIC-------------------RAV 3471
Query: 1438 CRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQE--------MQGQCSVPNELNSNLK 1489
CR C++ Q N C + W G +C+E G+C P + +
Sbjct: 3472 CRFPCQNGGICQ--RPNACSCPEG--WMG--RLCEEPICILPCLNGGRCVAPYQCD---- 3521
Query: 1490 LQCPDGYAIGSECATS 1505
CP G+ GS C T+
Sbjct: 3522 --CPPGWT-GSRCHTA 3534
Score = 67.0 bits (162), Expect = 1e-10
Identities = 75/339 (22%), Positives = 128/339 (37%), Gaps = 61/339 (17%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIR 1251
C +S ++Q C+ +C++ V++AS ++ R G C GY L
Sbjct: 2003 CLADGKWSRSDQQCLAVSCDEPPI----VDHASPE--TAHRLFGDIAFYYCSDGYSL--- 2053
Query: 1252 RDDELIKSQTGPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTT-----F 1306
S + +GKW + C + + S+S E +
Sbjct: 2054 ---------ADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAA 2104
Query: 1307 GSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALC----ELMCLAPPPVPNADLQTARC 1362
GS SF+C L ++ + CM G W+ P + + C PP + N
Sbjct: 2105 GSVVSFKCMEGFVLN-TSAKIECMRGGQWN-PSPMSIQCIPVRCGEPPSIMNG-----YA 2157
Query: 1363 RENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEG--ACVPVTCDPPPP 1420
+ + G+ Y C G+++ G K+ C G W C PV+C PP
Sbjct: 2158 SGSNYSFGAMVAYSCNKGFYIKGEK--------KSTCEATGQWSSPIPTCHPVSCGEPPK 2209
Query: 1421 KFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNG-SFHVCQEMQGQCS 1479
+G + T G F SE R +C + + +GS V C+ + W+ S +C + C
Sbjct: 2210 VENGFLEHTTGRIFESEVRYQC--NPGYKSVGSPVFVCQANRHWHSESPLMCVPL--DCG 2265
Query: 1480 VPN------------ELNSNLKLQCPDGYAIGSECATSC 1506
P E+ S ++ C +GY + + + +C
Sbjct: 2266 KPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTC 2304
Score = 64.3 bits (155), Expect = 9e-10
Identities = 73/346 (21%), Positives = 118/346 (34%), Gaps = 81/346 (23%)
Query: 1213 TDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEG 1272
+DCP L L +S D G++ + C G+ L G V +G
Sbjct: 1629 SDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQL------------VGNPVQYCLNQG 1676
Query: 1273 KWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCME 1331
+W + + CE + C +P + F + GS ++QC + L G +S + C +
Sbjct: 1677 QWTQPLPHCERISCGVPPPLE---NGFHSADDFYAGSTVTYQCNNGYYLLG-DSRMFCTD 1732
Query: 1332 DGLWSFPEALC-----------------------ELMCLAPPPVPNADLQTA---RCR-- 1363
+G W+ C +C PP A +C+
Sbjct: 1733 NGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAP 1792
Query: 1364 ---ENKHK------VGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQE--GACVP 1412
EN H VG+ + C+ GY + G + K C + G W C
Sbjct: 1793 GNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVT--------KITCLESGEWNHLIPYCKA 1844
Query: 1413 VTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
V+C P +G + F F S+ +C G C + +W+ S VC+
Sbjct: 1845 VSCGKPAIPENGCIE-ELAFTFGSKVTYRCNKGYTL--AGDKESSCLANSSWSHSPPVCE 1901
Query: 1473 EMQGQCSVPNELN------------SNLKLQCPDGYAIGSECATSC 1506
+ +CS P +N S C GY++ C
Sbjct: 1902 PV--KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIEC 1945
Score = 55.8 bits (133), Expect = 3e-07
Identities = 53/228 (23%), Positives = 85/228 (37%), Gaps = 24/228 (10%)
Query: 1269 CTEGKWNKQVACEPVDC-SIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLL 1327
C EG CE V C ++ Y +C F + C +C HP +S++
Sbjct: 362 CREGYRASGQTCELVHCPALKPPENGYFIQNTC--NNHFNAACGVRC-HPGFDLVGSSII 418
Query: 1328 TCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSS 1387
C+ +GLWS E+ C + P + RE +K + C C GY + GS
Sbjct: 419 LCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYK--TTCLVACDEGYRLEGSD 476
Query: 1388 RKSKKRAFKTQCTQDGSWQ--EGACVPVTCDP---PPPKFHGLYQC-TNGFQFNSECRIK 1441
K C + W E CV C P + C +F + C +
Sbjct: 477 --------KLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVS 528
Query: 1442 CEDSDASQGLGSNVIHCRKDGTWNGSFH--VCQEMQG-QCSVPNELNS 1486
C G+ ++ C G WN VC++++ Q + P ++ +
Sbjct: 529 CRQGFILSGV-KEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEA 575
Score = 39.7 bits (91), Expect = 0.024
Identities = 32/135 (23%), Positives = 50/135 (37%), Gaps = 24/135 (17%)
Query: 1210 CEKTDCPELAV-ENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELI----KSQTGPS 1264
C CP L ++ ++CS+ + + C V+C GY ++ D+L GP
Sbjct: 433 CRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGY--RLEGSDKLTCQGNSQWDGPE 490
Query: 1265 ---VTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLK 1321
V C+ + K V P +C + FG+ C CR L
Sbjct: 491 PRCVERHCSTFQMPKDVIISPHNCG--------------KQPAKFGTICYVSCRQGFILS 536
Query: 1322 GNNSLLTCMEDGLWS 1336
G +L C G W+
Sbjct: 537 GVKEMLRCTTSGKWN 551
Score = 38.5 bits (88), Expect = 0.054
Identities = 30/113 (26%), Positives = 42/113 (37%), Gaps = 21/113 (18%)
Query: 1191 SCQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQI 1250
+CQ + E CV C P+ + + NC G C VSCR G++L
Sbjct: 479 TCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPH-NCGKQPAKFGTICYVSCRQGFIL-- 535
Query: 1251 RRDDELIKSQTGPSVTVTC-TEGKWNKQVACEPVDCSIPDHHQVYAASFSCPE 1302
+G + C T GKWN V + C V A +CP+
Sbjct: 536 ----------SGVKEMLRCTTSGKWN--VGVQAAVCK-----DVEAPQINCPK 571
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 81.6 bits (200), Expect = 6e-15
Identities = 106/446 (23%), Positives = 165/446 (36%), Gaps = 102/446 (22%)
Query: 1210 CEKTDCPELAVENAS----LNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSV 1265
C+ CP + + + S S +GAQ +SC GY L+ R L++ Q
Sbjct: 2553 CKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWR---LLRCQ----- 2604
Query: 1266 TVTCTEGKWN---KQVACEPVDCSIPDHHQVYAASFSCPEG------TTFGSQCSFQCRH 1316
G WN ++ +C + C + SF P G T +G+ F C
Sbjct: 2605 ----ANGTWNIGDERPSCRVISCG--------SLSFP-PNGNKIGTLTVYGATAIFTCNT 2651
Query: 1317 PAQLKGNNSLLTCMEDGLWSFPEALCEL-MCLAPPPVPNADLQTARCRENKHKVGSFCKY 1375
L G++ + C+ +GLWS E C C +P P+ N + + Y
Sbjct: 2652 GYTLVGSH-VRECLANGLWSGSETRCLAGHCGSPDPIVNGHIS-----GDGFSYRDTVVY 2705
Query: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGLYQCTNG-- 1431
+C PG+ + G+S + C QD W Q CVP+TC P HG TNG
Sbjct: 2706 QCNPGFRLVGTSVRI--------CLQDHKWSGQTPVCVPITCGHPGNPAHGF---TNGSE 2754
Query: 1432 FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEM-------------QGQC 1478
F N C QG+ CR +G W+ C+ + GQ
Sbjct: 2755 FNLNDVVNFTCNTGYLLQGVSR--AQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQ 2812
Query: 1479 SVPN--ELNSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTVRDIPHWLNPTRVER 1536
+ P E ++ C G+ + A +C+ + LP + + +P
Sbjct: 2813 NFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAI----SCGHPGVPAN 2868
Query: 1537 VVCTAGLKWYPHPALIH-CVKGCEPFMGDN---------------YCDAINNRAFCNYDG 1580
V T L + + A++H +G E +G++ +C NN FC G
Sbjct: 2869 AVLTGEL--FTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTG-NNPGFCGDPG 2925
Query: 1581 ----GDCCTSTVKTKKVTPFPMSCDL 1602
G KTK + F SC++
Sbjct: 2926 TPAHGSRLGDDFKTKSLLRF--SCEM 2949
Score = 73.2 bits (178), Expect = 2e-12
Identities = 88/389 (22%), Positives = 133/389 (34%), Gaps = 109/389 (28%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENAS-LNCSSSDRYHGAQCTVSCRTGYVLQI 1250
C + +S CV C P N S N + + +C TGY+LQ
Sbjct: 2721 CLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNF-------TCNTGYLLQ- 2772
Query: 1251 RRDDELIKSQTGPSVTVTCTEGKWNKQV-ACEPVDCSIPD--HHQVYAASFSCPEGTTFG 1307
G S + G+W+ + C V+CS P + + + PE +G
Sbjct: 2773 -----------GVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYG 2821
Query: 1308 SQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVP-NADL--------- 1357
+ C+ L G+ S LTCM +GLW C + P VP NA L
Sbjct: 2822 MSILYHCKKGFYLLGS-SALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGA 2880
Query: 1358 ---------------QTARCRENKH--------------------------------KVG 1370
T C+E+ H K
Sbjct: 2881 VVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTK 2940
Query: 1371 SFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQ--EGACVPVTCDPPPPKFHGLYQC 1428
S ++ C+ G+ + GS ++ C +GSW + C V+C P +G+
Sbjct: 2941 SLLRFSCEMGHQLRGSPERT--------CLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVS 2992
Query: 1429 TNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNEL---- 1484
++G F+S C + + GL + HC +GTW G+ C + C P L
Sbjct: 2993 SDGILFSSSVIYACWEGYKTSGLMTR--HCTANGTWTGTAPDCTII--SCGDPGTLANGI 3048
Query: 1485 --------NSNLKLQCPDGYAIGSECATS 1505
N + QC GY + E TS
Sbjct: 3049 QFGTDFTFNKTVSYQCNPGYVM--EAVTS 3075
Score = 72.0 bits (175), Expect = 4e-12
Identities = 70/288 (24%), Positives = 110/288 (38%), Gaps = 42/288 (14%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIR 1251
C + ++P++ C C + V+N ++ SD G+ + SC GY
Sbjct: 3080 CTKDGRWNPSKPVCKAVLCPQPP----PVQNGTVE--GSDFRWGSSISYSCMDGY----- 3128
Query: 1252 RDDELIKSQTGPSVTVTCT-EGKWNKQVA-CEPVDCS---IPDHHQVYAASFSCPEGTTF 1306
Q S ++C G W ++ C PV C IP ++ SF T+
Sbjct: 3129 --------QLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSF------TY 3174
Query: 1307 GSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENK 1366
S+ FQC+ P L G+ S C DG WS + C P P +
Sbjct: 3175 KSEVFFQCKSPFILVGS-SRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRG 3233
Query: 1367 HKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQ--EGACVPVTCDPPPPKFHG 1424
++VGS ++C+ GYH+ GS+ ++ C + +W + C+P C P H
Sbjct: 3234 YEVGSTVFFRCRKGYHIQGSTTRT--------CLANLTWSGIQTECIPHACRQPETPAHA 3285
Query: 1425 LYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
+ + F C G GS C+ D W G VC+
Sbjct: 3286 DVRAIDLPTFGYTLVYTCHPGFFLAG-GSEHRTCKADMKWTGKSPVCK 3332
Score = 69.3 bits (168), Expect = 3e-11
Identities = 54/209 (25%), Positives = 80/209 (38%), Gaps = 29/209 (13%)
Query: 1312 FQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGS 1371
F C QL+G+ TC+ +G WS + +CE + P P + + + S
Sbjct: 2945 FSCEMGHQLRGSPER-TCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVS---SDGILFSS 3000
Query: 1372 FCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCT 1429
Y C GY G + CT +G+W A C ++C P +G+ Q
Sbjct: 3001 SVIYACWEGYKTSGLMTR--------HCTANGTWTGTAPDCTIISCGDPGTLANGI-QFG 3051
Query: 1430 NGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNEL----- 1484
F FN +C + + S I C KDG WN S VC+ + C P +
Sbjct: 3052 TDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAV--LCPQPPPVQNGTV 3109
Query: 1485 -------NSNLKLQCPDGYAIGSECATSC 1506
S++ C DGY + SC
Sbjct: 3110 EGSDFRWGSSISYSCMDGYQLSHSAILSC 3138
Score = 49.3 bits (116), Expect = 3e-05
Identities = 63/278 (22%), Positives = 103/278 (37%), Gaps = 66/278 (23%)
Query: 1280 CEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNN-SLLTCMEDGLWSFP 1338
C+ V C IP+ SF+ E T S+ ++C +L+ + + C EDGLWS
Sbjct: 2491 CQAVSCGIPESPG--NGSFTGNE-FTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNK 2547
Query: 1339 EALCELMCLAPPPVPNADLQTARCRENKHKV-----GSFCKY------KCKPGYHVPGSS 1387
PP + + ++H + GS +Y C PGY++ G
Sbjct: 2548 GK--------PPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWR 2599
Query: 1388 RKSKKRAFKTQCTQDGSWQEG----ACVPVTCD----PPPPKFHG---LYQCTNGFQFNS 1436
+C +G+W G +C ++C PP G +Y T F N+
Sbjct: 2600 L--------LRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNT 2651
Query: 1437 ECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNEL------------ 1484
+ +GS+V C +G W+GS C + G C P+ +
Sbjct: 2652 GYTL----------VGSHVRECLANGLWSGSETRC--LAGHCGSPDPIVNGHISGDGFSY 2699
Query: 1485 NSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTV 1522
+ QC G+ + CL + S P+ V +
Sbjct: 2700 RDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPI 2737
Score = 38.9 bits (89), Expect = 0.041
Identities = 35/145 (24%), Positives = 53/145 (36%), Gaps = 20/145 (13%)
Query: 1369 VGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQC 1428
VGS Y CKPGY + G S + +R D C V+C P +G +
Sbjct: 2452 VGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDS--LTPLCQAVSCGIPESPGNGSF-T 2508
Query: 1429 TNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFH-------VCQEMQGQCSVP 1481
N F +S+ +C + + C++DG W+ C ++ Q S
Sbjct: 2509 GNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEH 2568
Query: 1482 ----------NELNSNLKLQCPDGY 1496
NE + + L C GY
Sbjct: 2569 VIWRLVSGSLNEYGAQVLLSCSPGY 2593
Score = 38.5 bits (88), Expect = 0.054
Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 1346 CLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGS 1386
C PP VP A++ T ++ ++G F KY+C PGY + G+
Sbjct: 2259 CQPPPAVPQAEMLT---EDDDFEIGDFVKYQCHPGYTLVGT 2296
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 78.2 bits (191), Expect = 6e-14
Identities = 73/295 (24%), Positives = 115/295 (38%), Gaps = 40/295 (13%)
Query: 1187 VTLSSCQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGY 1246
V++ SC + T++ + C C+ P + N + SD G+ T +C GY
Sbjct: 2989 VSVLSCTKDRTWNGTKPVCKALMCK----PPPLIPNGKV--VGSDFMWGSSVTYACLEGY 3042
Query: 1247 VLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTT 1305
L + P+V G W ++ C PV C P V + G +
Sbjct: 3043 QLSL------------PAVFTCEGNGSWTGELPQCFPVFCGDPG---VPSRGRREDRGFS 3087
Query: 1306 FGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALC---ELMCLAPPPVPNADLQTARC 1362
+ S SF C P L G+ C DG WS + C L A P VP +Q
Sbjct: 3088 YRSSVSFSCHPPLVLVGSPRRF-CQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQN--- 3143
Query: 1363 RENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPP 1420
++VGS ++C+ GY + GS+ ++ C + +W CVP C P
Sbjct: 3144 NSQGYQVGSTVLFRCQKGYLLQGSTTRT--------CLPNLTWSGTPPDCVPHHCRQPET 3195
Query: 1421 KFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQ 1475
H + C++ + +G GS C+ DG+W G +C E++
Sbjct: 3196 PTHANVGALDLPSMGYTLIYSCQEGFSLKG-GSEHRTCKADGSWTGKPPICLEVR 3249
Score = 65.5 bits (158), Expect = 4e-10
Identities = 60/276 (21%), Positives = 106/276 (38%), Gaps = 32/276 (11%)
Query: 1258 KSQTGPSVTVTCTEGKWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRH 1316
++ G S + +G W + C + + A + G+ F C
Sbjct: 2804 RTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEA 2863
Query: 1317 PAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKV-GSFCKY 1375
L+G++ TC +G WS + C ++ P P+ AR + V S Y
Sbjct: 2864 GHVLRGSSER-TCQANGSWSGSQPECGVISCGNPGTPS----NARVVFSDGLVFSSSIVY 2918
Query: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGLYQCTNGFQ 1433
+C+ GY+ G C+ +G+W + C+ + C P +GL + N F+
Sbjct: 2919 ECREGYYATG--------LLSRHCSVNGTWTGSDPECLVINCGDPGIPANGL-RLGNDFR 2969
Query: 1434 FNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNEL--------- 1484
+N +C + +V+ C KD TWNG+ VC+ + C P +
Sbjct: 2970 YNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKAL--MCKPPPLIPNGKVVGSD 3027
Query: 1485 ---NSNLKLQCPDGYAIGSECATSCLDHNSESIILP 1517
S++ C +GY + +C + S + LP
Sbjct: 3028 FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELP 3063
Score = 58.2 bits (139), Expect = 7e-08
Identities = 72/304 (23%), Positives = 107/304 (35%), Gaps = 43/304 (14%)
Query: 1210 CEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTC 1269
C C EL + + Y GA SC +GY L G V
Sbjct: 2653 CRIISCGELPIPPNGHRIGTLSVY-GATAIFSCNSGYTL------------VGSRVRECM 2699
Query: 1270 TEGKWN-KQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLT 1328
G W+ +V C C P + E ++ +QC +L G S+
Sbjct: 2700 ANGLWSGSEVRCLAGHCGTP---EPIVNGHINGENYSYRGSVVYQCNAGFRLIG-MSVRI 2755
Query: 1329 CMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSR 1388
C +D WS C L+ P P ++ + + VG+ +Y C + G+S
Sbjct: 2756 CQQDHHWSGKTPFCVLVSCGHPGSP----PHSQMSGDSYTVGAVVRYSCIGKRTLVGNST 2811
Query: 1389 KSKKRAFKTQCTQDGSWQ------EGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKC 1442
+ C DG W G V V DP P HG+ + + F + R C
Sbjct: 2812 R--------MCGLDGHWTGSLPHCSGTSVGVCGDPGIPA-HGI-RLGDSFDPGTVMRFSC 2861
Query: 1443 EDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSEC 1502
E + GS+ C+ +G+W+GS C + C P SN ++ DG S
Sbjct: 2862 EAGHVLR--GSSERTCQANGSWSGSQPECGVI--SCGNPG-TPSNARVVFSDGLVFSSSI 2916
Query: 1503 ATSC 1506
C
Sbjct: 2917 VYEC 2920
Score = 57.0 bits (136), Expect = 1e-07
Identities = 52/230 (22%), Positives = 91/230 (39%), Gaps = 45/230 (19%)
Query: 1274 WNKQVA-CEPVDCSIPD---HHQVYAASFSCPEGTTFGSQCSFQCRHPAQLK-GNNSLLT 1328
W++ + C+ + C +P+ + V+ + T G++ + C L+ G +
Sbjct: 2519 WSEAIPLCQALSCGLPEAPKNGMVFGKEY------TVGTKAMYSCSEGYHLQAGAEATAE 2572
Query: 1329 CMEDGLWSFPEALCELMCLAPPPVPNADLQTARCR---ENKHKVGSFCKYKCKPGYHVPG 1385
C++ GLWS + + + P V + ++ R R E +++ + C PGY+ G
Sbjct: 2573 CLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTG 2632
Query: 1386 SSRKSKKRAFKTQCTQDGSWQEGACVP----VTCD--PPPPKFH-----GLYQCTNGFQF 1434
+C +G W G P ++C P PP H +Y T F
Sbjct: 2633 QR--------VIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSC 2684
Query: 1435 NSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNEL 1484
NS + +GS V C +G W+GS C + G C P +
Sbjct: 2685 NSGYTL----------VGSRVRECMANGLWSGSEVRC--LAGHCGTPEPI 2722
>gi|7657619 sushi-repeat-containing protein, X-linked 2 [Homo sapiens]
Length = 465
Score = 73.9 bits (180), Expect = 1e-12
Identities = 68/299 (22%), Positives = 114/299 (38%), Gaps = 72/299 (24%)
Query: 1215 CPELAVENASLNCSS--SDRYH---GAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTC 1269
C L +++ C S YH G +C +SC G+ L RR + + S+
Sbjct: 59 CYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSR--------- 109
Query: 1270 TEGKWNKQVACEPVDC-SIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLT 1328
+W+ C + C ++P + + +++C G S+C + C L+G+ S +
Sbjct: 110 ---RWSGTAYCRQMRCHALPF---ITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRI- 162
Query: 1329 CMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCK---------- 1378
CMEDG WS E +C + + PP + RC ++ K+ K +
Sbjct: 163 CMEDGRWSGGEPVC--VDIDPPKI--------RCPHSREKMAEPEKLTARVYWDPPLVKD 212
Query: 1379 ---------------PGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVT------CDP 1417
PG H P + A+ D ++ +C + C
Sbjct: 213 SADGTITRVTLRGPEPGSHFPEGEHVIRYTAY------DRAYNRASCKFIVKVQVRRCPT 266
Query: 1418 PPPKFHGLYQCTN-GFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQ 1475
P HG CT+ G + + C C+ QG S V C+ W+GS +C M+
Sbjct: 267 LKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRV--CQSSRQWSGSPPICAPMK 323
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 70.5 bits (171), Expect = 1e-11
Identities = 76/340 (22%), Positives = 120/340 (35%), Gaps = 57/340 (16%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTV--SCRTGYVLQ 1249
C +S +E C+ C PEL V + +G + TV C G+ L
Sbjct: 2759 CLSSGLWSESETRCLAGHC---GIPELIVNGQVIG-----ENYGYRDTVVYQCNPGFRL- 2809
Query: 1250 IRRDDELIKSQTGPSVTVTCTEGKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTTFGS 1308
G SV + + W+ Q+ +C PV C P +Y + G F
Sbjct: 2810 -----------IGSSVRICQQDHNWSGQLPSCVPVSCGHPGS-PIYGRTSG--NGFNFND 2855
Query: 1309 QCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHK 1368
+F C ++G C + WS P +C+++ + P +P + ++
Sbjct: 2856 VVTFSCNIGYLMQGPTKA-QCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFT 2914
Query: 1369 VGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQE--GACVPVTCDPP--PPKFHG 1424
G+ Y C PGY + GSS C +G W + C+ + C P PP
Sbjct: 2915 YGTVVFYDCNPGYFLFGSS--------VLICQPNGQWDKPLPECIMIDCGHPGVPP---N 2963
Query: 1425 LYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSF-HVCQEMQGQCSVPN- 1482
+ F S C + G S C+ +G W+GS H + G C P
Sbjct: 2964 AVLSGEKYTFGSTVHYSCTGKRSLLGQSSRT--CQLNGHWSGSQPHCSGDATGTCGDPGT 3021
Query: 1483 -----------ELNSNLKLQCPDGYAIGSECATSCLDHNS 1511
S ++ C GY + +CL + S
Sbjct: 3022 PGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGS 3061
Score = 68.2 bits (165), Expect = 6e-11
Identities = 69/296 (23%), Positives = 107/296 (36%), Gaps = 50/296 (16%)
Query: 1241 SCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVA-CEPVDCSIPDHHQVYAASFS 1299
SC GY+L +GPSV G W+ + C + C P + A
Sbjct: 3100 SCMEGYIL------------SGPSVRQCTANGTWSGTLPNCTIISCGDPG---IPANGLR 3144
Query: 1300 CPEGTTFGSQCSFQCRHPAQLKGNNSLL-TCMEDGLWSFPEALCELM-CLAPPPVPNADL 1357
+ G S+ C+ ++ N S + TC +G WS C + C PP + N L
Sbjct: 3145 YGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRL 3204
Query: 1358 QTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTC 1415
+ G Y C PGY + + + C +G+W + C+P C
Sbjct: 3205 EGTN-----FDWGFSISYICSPGYELSFPAVLT--------CVGNGTWSGEVPQCLPKFC 3251
Query: 1416 DPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSF-HVCQEM 1474
P G + F + SE C G + + C+ DGTW+GS H +
Sbjct: 3252 GDPGIPAQGKRE-GKSFIYQSEVSFSCNFPFILVGSSTRI--CQADGTWSGSSPHCIEPT 3308
Query: 1475 QGQCSVPN-------------ELNSNLKLQCPDGYAIGSECATSCLDHNSESIILP 1517
Q C P ++ S ++ C G+ + +CL + S I P
Sbjct: 3309 QTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP 3364
Score = 60.5 bits (145), Expect = 1e-08
Identities = 63/273 (23%), Positives = 99/273 (36%), Gaps = 43/273 (15%)
Query: 1210 CEKTDCPELA-VENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVT 1268
C CP + N L ++ D G + C GY L P+V
Sbjct: 3188 CRAVTCPTPPQISNGRLEGTNFD--WGFSISYICSPGYELSF------------PAVLTC 3233
Query: 1269 CTEGKWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLL 1327
G W+ +V C P C P + A + + S+ SF C P L G+++ +
Sbjct: 3234 VGNGTWSGEVPQCLPKFCGDPG---IPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRI 3290
Query: 1328 TCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSS 1387
C DG WS C P ++ +VGS ++ CK G+ + GS+
Sbjct: 3291 -CQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGST 3349
Query: 1388 RKSKKRAFKTQCTQDGSWQ--EGACVPVTCDPPPPKFH----GLYQCTNGFQFNSECRIK 1441
++ C D +W + C+P +C P H G+ ++G+ C+
Sbjct: 3350 TRT--------CLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQ-- 3399
Query: 1442 CEDSDASQGLGSNVIH--CRKDGTWNGSFHVCQ 1472
L H CR D TW G +C+
Sbjct: 3400 -----PGFFLAGGTEHRVCRSDNTWTGKVPICE 3427
Score = 51.6 bits (122), Expect = 6e-06
Identities = 46/175 (26%), Positives = 65/175 (37%), Gaps = 25/175 (14%)
Query: 1303 GTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGL----WSFPEALCELMCLAPPPVP-NADL 1357
G S + C +L G +S + C + W P C+ + P P N +
Sbjct: 2545 GGQLNSVVRWACDRGFRLVGKSSAV-CRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGI 2603
Query: 1358 QTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEG----ACVPV 1413
T + VG+ Y C GY R S K C DG+W CV V
Sbjct: 2604 LTT-----DYLVGTRVTYFCNDGY------RLSSKELTTAVCQSDGTWSNHNKTPRCVVV 2652
Query: 1414 TCDPPPPKF---HGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWN 1465
TC P F HG ++ NG + + ++ GLG I C +GTW+
Sbjct: 2653 TC-PSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWS 2706
Score = 40.0 bits (92), Expect = 0.018
Identities = 15/43 (34%), Positives = 29/43 (67%), Gaps = 3/43 (6%)
Query: 1345 MCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSS 1387
+C PPPVPNA++ T +++ ++G +Y+C PG+ + G++
Sbjct: 2354 VCQPPPPVPNAEILT---EDDEFEIGDIIRYQCLPGFTLVGNA 2393
Score = 33.1 bits (74), Expect = 2.3
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
Query: 1283 VDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALC 1342
+D IP H + Y FS GS SF C +L LL C ++ WS P C
Sbjct: 971 LDPGIPVHGRRYGHDFS------IGSTVSFSCDSGYRLSHEEPLL-CEKNHWWSHPLPTC 1023
Query: 1343 ELMC 1346
+ +C
Sbjct: 1024 DALC 1027
Score = 31.2 bits (69), Expect = 8.6
Identities = 27/109 (24%), Positives = 38/109 (34%), Gaps = 20/109 (18%)
Query: 1415 CDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDG----TWNGSFHV 1470
C P HG G Q NS R C+ G S V CRK W+
Sbjct: 2529 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAV--CRKSSYGYHAWDAPVPA 2586
Query: 1471 CQEMQGQCSVPNE------------LNSNLKLQCPDGYAIGSECATSCL 1507
CQ + C +P + + + C DGY + S+ T+ +
Sbjct: 2587 CQAI--SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAV 2633
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 70.5 bits (171), Expect = 1e-11
Identities = 76/340 (22%), Positives = 120/340 (35%), Gaps = 57/340 (16%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTV--SCRTGYVLQ 1249
C +S +E C+ C PEL V + +G + TV C G+ L
Sbjct: 2630 CLSSGLWSESETRCLAGHC---GIPELIVNGQVIG-----ENYGYRDTVVYQCNPGFRL- 2680
Query: 1250 IRRDDELIKSQTGPSVTVTCTEGKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTTFGS 1308
G SV + + W+ Q+ +C PV C P +Y + G F
Sbjct: 2681 -----------IGSSVRICQQDHNWSGQLPSCVPVSCGHPGS-PIYGRTSG--NGFNFND 2726
Query: 1309 QCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHK 1368
+F C ++G C + WS P +C+++ + P +P + ++
Sbjct: 2727 VVTFSCNIGYLMQGPTKA-QCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFT 2785
Query: 1369 VGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQE--GACVPVTCDPP--PPKFHG 1424
G+ Y C PGY + GSS C +G W + C+ + C P PP
Sbjct: 2786 YGTVVFYDCNPGYFLFGSS--------VLICQPNGQWDKPLPECIMIDCGHPGVPP---N 2834
Query: 1425 LYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSF-HVCQEMQGQCSVPN- 1482
+ F S C + G S C+ +G W+GS H + G C P
Sbjct: 2835 AVLSGEKYTFGSTVHYSCTGKRSLLGQSSRT--CQLNGHWSGSQPHCSGDATGTCGDPGT 2892
Query: 1483 -----------ELNSNLKLQCPDGYAIGSECATSCLDHNS 1511
S ++ C GY + +CL + S
Sbjct: 2893 PGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGS 2932
Score = 68.2 bits (165), Expect = 6e-11
Identities = 69/296 (23%), Positives = 107/296 (36%), Gaps = 50/296 (16%)
Query: 1241 SCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVA-CEPVDCSIPDHHQVYAASFS 1299
SC GY+L +GPSV G W+ + C + C P + A
Sbjct: 2971 SCMEGYIL------------SGPSVRQCTANGTWSGTLPNCTIISCGDPG---IPANGLR 3015
Query: 1300 CPEGTTFGSQCSFQCRHPAQLKGNNSLL-TCMEDGLWSFPEALCELM-CLAPPPVPNADL 1357
+ G S+ C+ ++ N S + TC +G WS C + C PP + N L
Sbjct: 3016 YGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRL 3075
Query: 1358 QTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTC 1415
+ G Y C PGY + + + C +G+W + C+P C
Sbjct: 3076 EGTN-----FDWGFSISYICSPGYELSFPAVLT--------CVGNGTWSGEVPQCLPKFC 3122
Query: 1416 DPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSF-HVCQEM 1474
P G + F + SE C G + + C+ DGTW+GS H +
Sbjct: 3123 GDPGIPAQGKRE-GKSFIYQSEVSFSCNFPFILVGSSTRI--CQADGTWSGSSPHCIEPT 3179
Query: 1475 QGQCSVPN-------------ELNSNLKLQCPDGYAIGSECATSCLDHNSESIILP 1517
Q C P ++ S ++ C G+ + +CL + S I P
Sbjct: 3180 QTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP 3235
Score = 60.5 bits (145), Expect = 1e-08
Identities = 63/273 (23%), Positives = 99/273 (36%), Gaps = 43/273 (15%)
Query: 1210 CEKTDCPELA-VENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVT 1268
C CP + N L ++ D G + C GY L P+V
Sbjct: 3059 CRAVTCPTPPQISNGRLEGTNFD--WGFSISYICSPGYELSF------------PAVLTC 3104
Query: 1269 CTEGKWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLL 1327
G W+ +V C P C P + A + + S+ SF C P L G+++ +
Sbjct: 3105 VGNGTWSGEVPQCLPKFCGDPG---IPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRI 3161
Query: 1328 TCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSS 1387
C DG WS C P ++ +VGS ++ CK G+ + GS+
Sbjct: 3162 -CQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGST 3220
Query: 1388 RKSKKRAFKTQCTQDGSWQ--EGACVPVTCDPPPPKFH----GLYQCTNGFQFNSECRIK 1441
++ C D +W + C+P +C P H G+ ++G+ C+
Sbjct: 3221 TRT--------CLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQ-- 3270
Query: 1442 CEDSDASQGLGSNVIH--CRKDGTWNGSFHVCQ 1472
L H CR D TW G +C+
Sbjct: 3271 -----PGFFLAGGTEHRVCRSDNTWTGKVPICE 3298
Score = 40.0 bits (92), Expect = 0.018
Identities = 15/43 (34%), Positives = 29/43 (67%), Gaps = 3/43 (6%)
Query: 1345 MCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSS 1387
+C PPPVPNA++ T +++ ++G +Y+C PG+ + G++
Sbjct: 2290 VCQPPPPVPNAEILT---EDDEFEIGDIIRYQCLPGFTLVGNA 2329
Score = 33.1 bits (74), Expect = 2.3
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
Query: 1283 VDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALC 1342
+D IP H + Y FS GS SF C +L LL C ++ WS P C
Sbjct: 907 LDPGIPVHGRRYGHDFS------IGSTVSFSCDSGYRLSHEEPLL-CEKNHWWSHPLPTC 959
Query: 1343 ELMC 1346
+ +C
Sbjct: 960 DALC 963
Score = 31.2 bits (69), Expect = 8.6
Identities = 27/109 (24%), Positives = 38/109 (34%), Gaps = 20/109 (18%)
Query: 1415 CDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDG----TWNGSFHV 1470
C P HG G Q NS R C+ G S V CRK W+
Sbjct: 2465 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAV--CRKSSYGYHAWDAPVPA 2522
Query: 1471 CQEMQGQCSVPNE------------LNSNLKLQCPDGYAIGSECATSCL 1507
CQ + C +P + + + C DGY + S+ T+ +
Sbjct: 2523 CQAI--SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAV 2569
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 70.5 bits (171), Expect = 1e-11
Identities = 76/340 (22%), Positives = 120/340 (35%), Gaps = 57/340 (16%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTV--SCRTGYVLQ 1249
C +S +E C+ C PEL V + +G + TV C G+ L
Sbjct: 2799 CLSSGLWSESETRCLAGHC---GIPELIVNGQVIG-----ENYGYRDTVVYQCNPGFRL- 2849
Query: 1250 IRRDDELIKSQTGPSVTVTCTEGKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTTFGS 1308
G SV + + W+ Q+ +C PV C P +Y + G F
Sbjct: 2850 -----------IGSSVRICQQDHNWSGQLPSCVPVSCGHPGS-PIYGRTSG--NGFNFND 2895
Query: 1309 QCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHK 1368
+F C ++G C + WS P +C+++ + P +P + ++
Sbjct: 2896 VVTFSCNIGYLMQGPTKA-QCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFT 2954
Query: 1369 VGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQE--GACVPVTCDPP--PPKFHG 1424
G+ Y C PGY + GSS C +G W + C+ + C P PP
Sbjct: 2955 YGTVVFYDCNPGYFLFGSS--------VLICQPNGQWDKPLPECIMIDCGHPGVPP---N 3003
Query: 1425 LYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSF-HVCQEMQGQCSVPN- 1482
+ F S C + G S C+ +G W+GS H + G C P
Sbjct: 3004 AVLSGEKYTFGSTVHYSCTGKRSLLGQSSRT--CQLNGHWSGSQPHCSGDATGTCGDPGT 3061
Query: 1483 -----------ELNSNLKLQCPDGYAIGSECATSCLDHNS 1511
S ++ C GY + +CL + S
Sbjct: 3062 PGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGS 3101
Score = 68.2 bits (165), Expect = 6e-11
Identities = 69/296 (23%), Positives = 107/296 (36%), Gaps = 50/296 (16%)
Query: 1241 SCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVA-CEPVDCSIPDHHQVYAASFS 1299
SC GY+L +GPSV G W+ + C + C P + A
Sbjct: 3140 SCMEGYIL------------SGPSVRQCTANGTWSGTLPNCTIISCGDPG---IPANGLR 3184
Query: 1300 CPEGTTFGSQCSFQCRHPAQLKGNNSLL-TCMEDGLWSFPEALCELM-CLAPPPVPNADL 1357
+ G S+ C+ ++ N S + TC +G WS C + C PP + N L
Sbjct: 3185 YGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRL 3244
Query: 1358 QTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTC 1415
+ G Y C PGY + + + C +G+W + C+P C
Sbjct: 3245 EGTN-----FDWGFSISYICSPGYELSFPAVLT--------CVGNGTWSGEVPQCLPKFC 3291
Query: 1416 DPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSF-HVCQEM 1474
P G + F + SE C G + + C+ DGTW+GS H +
Sbjct: 3292 GDPGIPAQGKRE-GKSFIYQSEVSFSCNFPFILVGSSTRI--CQADGTWSGSSPHCIEPT 3348
Query: 1475 QGQCSVPN-------------ELNSNLKLQCPDGYAIGSECATSCLDHNSESIILP 1517
Q C P ++ S ++ C G+ + +CL + S I P
Sbjct: 3349 QTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP 3404
Score = 60.5 bits (145), Expect = 1e-08
Identities = 63/273 (23%), Positives = 99/273 (36%), Gaps = 43/273 (15%)
Query: 1210 CEKTDCPELA-VENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVT 1268
C CP + N L ++ D G + C GY L P+V
Sbjct: 3228 CRAVTCPTPPQISNGRLEGTNFD--WGFSISYICSPGYELSF------------PAVLTC 3273
Query: 1269 CTEGKWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLL 1327
G W+ +V C P C P + A + + S+ SF C P L G+++ +
Sbjct: 3274 VGNGTWSGEVPQCLPKFCGDPG---IPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRI 3330
Query: 1328 TCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSS 1387
C DG WS C P ++ +VGS ++ CK G+ + GS+
Sbjct: 3331 -CQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGST 3389
Query: 1388 RKSKKRAFKTQCTQDGSWQ--EGACVPVTCDPPPPKFH----GLYQCTNGFQFNSECRIK 1441
++ C D +W + C+P +C P H G+ ++G+ C+
Sbjct: 3390 TRT--------CLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQ-- 3439
Query: 1442 CEDSDASQGLGSNVIH--CRKDGTWNGSFHVCQ 1472
L H CR D TW G +C+
Sbjct: 3440 -----PGFFLAGGTEHRVCRSDNTWTGKVPICE 3467
Score = 51.6 bits (122), Expect = 6e-06
Identities = 46/175 (26%), Positives = 65/175 (37%), Gaps = 25/175 (14%)
Query: 1303 GTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGL----WSFPEALCELMCLAPPPVP-NADL 1357
G S + C +L G +S + C + W P C+ + P P N +
Sbjct: 2585 GGQLNSVVRWACDRGFRLVGKSSAV-CRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGI 2643
Query: 1358 QTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEG----ACVPV 1413
T + VG+ Y C GY R S K C DG+W CV V
Sbjct: 2644 LTT-----DYLVGTRVTYFCNDGY------RLSSKELTTAVCQSDGTWSNHNKTPRCVVV 2692
Query: 1414 TCDPPPPKF---HGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWN 1465
TC P F HG ++ NG + + ++ GLG I C +GTW+
Sbjct: 2693 TC-PSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWS 2746
Score = 40.0 bits (92), Expect = 0.018
Identities = 15/43 (34%), Positives = 29/43 (67%), Gaps = 3/43 (6%)
Query: 1345 MCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSS 1387
+C PPPVPNA++ T +++ ++G +Y+C PG+ + G++
Sbjct: 2394 VCQPPPPVPNAEILT---EDDEFEIGDIIRYQCLPGFTLVGNA 2433
Score = 33.1 bits (74), Expect = 2.3
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
Query: 1283 VDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALC 1342
+D IP H + Y FS GS SF C +L LL C ++ WS P C
Sbjct: 1011 LDPGIPVHGRRYGHDFS------IGSTVSFSCDSGYRLSHEEPLL-CEKNHWWSHPLPTC 1063
Query: 1343 ELMC 1346
+ +C
Sbjct: 1064 DALC 1067
Score = 31.2 bits (69), Expect = 8.6
Identities = 27/109 (24%), Positives = 38/109 (34%), Gaps = 20/109 (18%)
Query: 1415 CDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDG----TWNGSFHV 1470
C P HG G Q NS R C+ G S V CRK W+
Sbjct: 2569 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAV--CRKSSYGYHAWDAPVPA 2626
Query: 1471 CQEMQGQCSVPNE------------LNSNLKLQCPDGYAIGSECATSCL 1507
CQ + C +P + + + C DGY + S+ T+ +
Sbjct: 2627 CQAI--SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAV 2673
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 70.1 bits (170), Expect = 2e-11
Identities = 86/358 (24%), Positives = 134/358 (37%), Gaps = 70/358 (19%)
Query: 1196 ETYSPAEQSCVHFACEKTDCPELAVENA-SLNCSSSDRY--HGAQCTVSCRTGYVLQIRR 1252
+ +SP ++ V ++CE P + A SL+C+ + +C V ++ Q+
Sbjct: 1664 DNFSPGQE--VFYSCE----PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPH 1717
Query: 1253 DDEL--IKSQTGPSVTVTCTEG------------------KWNKQV-ACEPVDCSIPDHH 1291
L + Q G V+ C EG WN V CE + C P
Sbjct: 1718 GRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAI 1777
Query: 1292 QVYAASFSCPEGTT-FGSQCSFQCR-HPAQLKGNN----SLLTCMED----GLWSFPEAL 1341
+ P G +G + S+ C HP + N S + C D G+WS P
Sbjct: 1778 -LNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPR 1836
Query: 1342 CELM-----CLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFK 1396
CEL C P P A T + + VG+ Y+C+PGY + F
Sbjct: 1837 CELSVRAGHCKTPEQFPFAS-PTIPINDFEFPVGTSLNYECRPGYF---------GKMFS 1886
Query: 1397 TQCTQDGSWQ--EGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSN 1454
C ++ W E C +C PPP F+G+ QF S C ++ + +GS
Sbjct: 1887 ISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSC--NEGFRLIGSP 1944
Query: 1455 VIHCRKDG---TWNGSFHVCQEMQGQCSVP-----NELNSNLKLQCPDGYAIGSECAT 1504
C G TW+ +C+ + C P + SN + +G + +C T
Sbjct: 1945 STTCLVSGNNVTWDKKAPICEII--SCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 2000
Score = 57.0 bits (136), Expect = 1e-07
Identities = 81/365 (22%), Positives = 127/365 (34%), Gaps = 85/365 (23%)
Query: 1266 TVTCTEGKWNKQVACEPVD-------CSIPDHHQVYAASFSCPEGTTF--GSQCSFQCRH 1316
T+ CT V P C PDH ++A + + F G+ ++CR
Sbjct: 467 TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHF-LFAKLKTQTNASDFPIGTSLKYECR- 524
Query: 1317 PAQLKGNNSLLTCMEDGLWSFPEALCE-LMCLAPPPVPNADLQTARCRENKHKVGSFCKY 1375
+ G +TC+++ +WS P+ +C+ C PP N + +VGS Y
Sbjct: 525 -PEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVI----TDIQVGSRINY 579
Query: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDG-----SWQEGACVPVTCDPPPPKFHGLYQCTN 1430
C G+ + G S +C G S + C + C PP +G + TN
Sbjct: 580 SCTTGHRLIGHS--------SAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTN 631
Query: 1431 --GFQFNSECRIKCEDSDASQG----LGSNVIHCRKD----GTWNGSFHVCQEMQGQCSV 1480
F + S +C + +G I+C + G W+G C + +C+
Sbjct: 632 RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC-IIPNKCTP 690
Query: 1481 PN--------------ELNSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTV-RDI 1525
PN LN ++ +C G+ + C N LP V +
Sbjct: 691 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 750
Query: 1526 PHWLNPTRVER--------------------------VVCTAGLKWYPHPALIHC-VKGC 1558
P L+ R +R + CT W PA C VK C
Sbjct: 751 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDW--SPAAPTCEVKSC 808
Query: 1559 EPFMG 1563
+ FMG
Sbjct: 809 DDFMG 813
Score = 57.0 bits (136), Expect = 1e-07
Identities = 81/365 (22%), Positives = 127/365 (34%), Gaps = 85/365 (23%)
Query: 1266 TVTCTEGKWNKQVACEPVD-------CSIPDHHQVYAASFSCPEGTTF--GSQCSFQCRH 1316
T+ CT V P C PDH ++A + + F G+ ++CR
Sbjct: 917 TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHF-LFAKLKTQTNASDFPIGTSLKYECR- 974
Query: 1317 PAQLKGNNSLLTCMEDGLWSFPEALCE-LMCLAPPPVPNADLQTARCRENKHKVGSFCKY 1375
+ G +TC+++ +WS P+ +C+ C PP N + +VGS Y
Sbjct: 975 -PEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVI----TDIQVGSRINY 1029
Query: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDG-----SWQEGACVPVTCDPPPPKFHGLYQCTN 1430
C G+ + G S +C G S + C + C PP +G + TN
Sbjct: 1030 SCTTGHRLIGHS--------SAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
Query: 1431 --GFQFNSECRIKCEDSDASQG----LGSNVIHCRKD----GTWNGSFHVCQEMQGQCSV 1480
F + S +C + +G I+C + G W+G C + +C+
Sbjct: 1082 RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC-IIPNKCTP 1140
Query: 1481 PN--------------ELNSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTV-RDI 1525
PN LN ++ +C G+ + C N LP V +
Sbjct: 1141 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 1200
Query: 1526 PHWLNPTRVER--------------------------VVCTAGLKWYPHPALIHC-VKGC 1558
P L+ R +R + CT W PA C VK C
Sbjct: 1201 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDW--SPAAPTCEVKSC 1258
Query: 1559 EPFMG 1563
+ FMG
Sbjct: 1259 DDFMG 1263
Score = 55.8 bits (133), Expect = 3e-07
Identities = 74/317 (23%), Positives = 116/317 (36%), Gaps = 56/317 (17%)
Query: 1266 TVTCTEGKWNKQVACEPVD-------CSIPDHHQVYAASFSCPEGTTF--GSQCSFQCRH 1316
T+ CT V P C PDH ++A + + F G+ ++CR
Sbjct: 1367 TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHF-LFAKLKTQTNASDFPIGTSLKYECR- 1424
Query: 1317 PAQLKGNNSLLTCMEDGLWSFPEALCE-LMCLAPPPVPNADLQTARCRENKHKVGSFCKY 1375
+ G +TC+++ +WS P+ +C+ C PP N + +VGS Y
Sbjct: 1425 -PEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVI----TDIQVGSRINY 1479
Query: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTN--GFQ 1433
C G+ + G S + T S + C + C PP +G + TN F
Sbjct: 1480 SCTTGHRLIG---HSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFH 1536
Query: 1434 FNS----ECRIKCEDSDASQGLGSNVIHCRKD----GTWNGSFHVCQEMQGQCSVPNELN 1485
+ S C + + +G I+C + G W+G C + +C+ PN N
Sbjct: 1537 YGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC-IIPNKCTPPNVEN 1595
Query: 1486 SNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTVRDIPHWL--NPTRVERVVCTAGL 1543
L + N L V R P ++ P RV+ C A
Sbjct: 1596 GIL------------------VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK---CQALN 1634
Query: 1544 KWYPHPALIHCVKGCEP 1560
KW P L C + C+P
Sbjct: 1635 KW--EPELPSCSRVCQP 1649
Score = 54.3 bits (129), Expect = 9e-07
Identities = 58/221 (26%), Positives = 89/221 (40%), Gaps = 29/221 (13%)
Query: 1302 EGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDG---LWSFPEALCE-LMCLAPPPVPNADL 1357
+G FGSQ + C +L G++S TC+ G +W +C+ + C PP + N D
Sbjct: 119 KGIQFGSQIKYSCTKGYRLIGSSS-ATCIISGDTVIWDNETPICDRIPCGLPPTITNGDF 177
Query: 1358 QTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQ--CT----QDGSWQEGA-- 1409
+ REN H GS Y+C PG RK + + CT Q G W A
Sbjct: 178 ISTN-RENFH-YGSVVTYRCNPG----SGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 231
Query: 1410 -CVPVTCDPPPPKFHGLYQCTNG--FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNG 1466
+P C PP + +G+ N F N +C+ + G + C+ W
Sbjct: 232 CIIPNKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFVMK--GPRRVKCQALNKWEP 288
Query: 1467 SFHVCQEMQGQCSVPNE-LNSNLKLQCPDGYAIGSECATSC 1506
C + C P + L++ + D ++ G E SC
Sbjct: 289 ELPSCSRV---CQPPPDVLHAERTQRDKDNFSPGQEVFYSC 326
Score = 53.1 bits (126), Expect = 2e-06
Identities = 78/318 (24%), Positives = 121/318 (38%), Gaps = 53/318 (16%)
Query: 1210 CEKTDC--PELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTV 1267
C++ C P ++ + + ++G+ T C G R+ EL+ PS+
Sbjct: 1061 CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGS--GGRKVFELVGE---PSIYC 1115
Query: 1268 TCTE---GKWNKQV--ACEPVDCSIPDHHQVYAAS-----FSCPEGTTFGSQCSFQCRHP 1317
T + G W+ P C+ P+ S FS E F Q F + P
Sbjct: 1116 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 1175
Query: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKC 1377
++K C W C +C PP V +A+ +T R ++N G Y C
Sbjct: 1176 RRVK-------CQALNKWEPELPSCSRVCQPPPDVLHAE-RTQRDKDN-FSPGQEVFYSC 1226
Query: 1378 KPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNG---F 1432
+PGY + G A +CT G W A C +CD F G Q NG F
Sbjct: 1227 EPGYDLRG--------AASMRCTPQGDWSPAAPTCEVKSCD----DFMG--QLLNGRVLF 1272
Query: 1433 QFNSECRIKCE--DSDASQGLGSNVIHC---RKDGTWNGSFHVCQEM--QGQCSVPNELN 1485
N + K + + Q GS+ +C + WN S VC+++ +PN +
Sbjct: 1273 PVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRH 1332
Query: 1486 SNLKLQC-PDGYAIGSEC 1502
+ L+ P G A+ C
Sbjct: 1333 TGKPLEVFPFGKAVNYTC 1350
Score = 51.6 bits (122), Expect = 6e-06
Identities = 77/318 (24%), Positives = 120/318 (37%), Gaps = 53/318 (16%)
Query: 1210 CEKTDC--PELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTV 1267
C++ C P ++ + + ++G+ T C G R+ EL+ PS+
Sbjct: 161 CDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS--GGRKVFELVGE---PSIYC 215
Query: 1268 TCTE---GKWNKQV--ACEPVDCSIPDHHQVYAAS-----FSCPEGTTFGSQCSFQCRHP 1317
T + G W+ P C+ P+ S FS E F Q F + P
Sbjct: 216 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
Query: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKC 1377
++K C W C +C PP V +A+ +T R ++N G Y C
Sbjct: 276 RRVK-------CQALNKWEPELPSCSRVCQPPPDVLHAE-RTQRDKDN-FSPGQEVFYSC 326
Query: 1378 KPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNG---F 1432
+PGY + G A +CT G W A C +CD F G Q NG F
Sbjct: 327 EPGYDLRG--------AASMRCTPQGDWSPAAPTCEVKSCD----DFMG--QLLNGRVLF 372
Query: 1433 QFNSECRIKCE--DSDASQGLGSNVIHC---RKDGTWNGSFHVCQEM--QGQCSVPNELN 1485
N + K + + Q GS+ +C + WN S VC+++ +PN +
Sbjct: 373 PVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRH 432
Query: 1486 SNLKLQC-PDGYAIGSEC 1502
+ L+ P G + C
Sbjct: 433 TGKPLEVFPFGKTVNYTC 450
Score = 51.6 bits (122), Expect = 6e-06
Identities = 77/318 (24%), Positives = 120/318 (37%), Gaps = 53/318 (16%)
Query: 1210 CEKTDC--PELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTV 1267
C++ C P ++ + + ++G+ T C G R+ EL+ PS+
Sbjct: 611 CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGS--GGRKVFELVGE---PSIYC 665
Query: 1268 TCTE---GKWNKQV--ACEPVDCSIPDHHQVYAAS-----FSCPEGTTFGSQCSFQCRHP 1317
T + G W+ P C+ P+ S FS E F Q F + P
Sbjct: 666 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 725
Query: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKC 1377
++K C W C +C PP V +A+ +T R ++N G Y C
Sbjct: 726 RRVK-------CQALNKWEPELPSCSRVCQPPPDVLHAE-RTQRDKDN-FSPGQEVFYSC 776
Query: 1378 KPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNG---F 1432
+PGY + G A +CT G W A C +CD F G Q NG F
Sbjct: 777 EPGYDLRG--------AASMRCTPQGDWSPAAPTCEVKSCD----DFMG--QLLNGRVLF 822
Query: 1433 QFNSECRIKCE--DSDASQGLGSNVIHC---RKDGTWNGSFHVCQEM--QGQCSVPNELN 1485
N + K + + Q GS+ +C + WN S VC+++ +PN +
Sbjct: 823 PVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRH 882
Query: 1486 SNLKLQC-PDGYAIGSEC 1502
+ L+ P G + C
Sbjct: 883 TGKPLEVFPFGKTVNYTC 900
Score = 51.6 bits (122), Expect = 6e-06
Identities = 65/295 (22%), Positives = 101/295 (34%), Gaps = 57/295 (19%)
Query: 1235 GAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGK-WNK-QVACEPVDCSIPDHHQ 1292
G CR GY G +++C E W+ + C C P +
Sbjct: 1869 GTSLNYECRPGYF--------------GKMFSISCLENLVWSSVEDNCRRKSCGPPP--E 1912
Query: 1293 VYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDG---LWSFPEALCELMCLAP 1349
+ T FGS ++ C +L G+ S TC+ G W +CE++ P
Sbjct: 1913 PFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPST-TCLVSGNNVTWDKKAPICEIISCEP 1971
Query: 1350 PP-VPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQD--GSWQ 1406
PP + N D + R + H G+ Y+C G +R+ D G W
Sbjct: 1972 PPTISNGDFYSNN-RTSFHN-GTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWS 2029
Query: 1407 EGACVPVTCDPPPPKFHGLYQCT--------------NGFQFNSECRIKCEDSDASQGLG 1452
PPP+ +CT + F R +C+ +G
Sbjct: 2030 S----------PPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVM--VG 2077
Query: 1453 SNVIHCRKDGTWNGSFHVCQEMQGQCSVPNE-LNSNLKLQCPDGYAIGSECATSC 1506
S+ + C+ +G W C + C P E L+ L D ++ G E SC
Sbjct: 2078 SHTVQCQTNGRWGPKLPHCSRV---CQPPPEILHGEHTLSHQDNFSPGQEVFYSC 2129
Score = 46.6 bits (109), Expect = 2e-04
Identities = 35/141 (24%), Positives = 58/141 (41%), Gaps = 19/141 (13%)
Query: 1346 CLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW 1405
C AP +P A T E + +G++ Y+C+PGY R F C ++ W
Sbjct: 43 CNAPEWLPFAR-PTNLTDEFEFPIGTYLNYECRPGY---------SGRPFSIICLKNSVW 92
Query: 1406 Q--EGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDG- 1462
+ C +C PP +G+ G QF S+ + C + + +GS+ C G
Sbjct: 93 TGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSC--TKGYRLIGSSSATCIISGD 150
Query: 1463 --TWNGSFHVCQEMQGQCSVP 1481
W+ +C + C +P
Sbjct: 151 TVIWDNETPICDRI--PCGLP 169
Score = 42.0 bits (97), Expect = 0.005
Identities = 55/234 (23%), Positives = 81/234 (34%), Gaps = 35/234 (14%)
Query: 1301 PEGTTFGSQCSFQCRHPAQLKGNNS---LLTCMEDGLWSFPEALCE-LMCLAPPPVPNAD 1356
P G++ SF C +LKG ++ +L M+ LW+ +CE + C PP + N
Sbjct: 2176 PLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMK-ALWNSSVPVCEQIFCPNPPAILNGR 2234
Query: 1357 LQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQD----GSWQEGA--- 1409
+ + G Y C H + +CT D G W A
Sbjct: 2235 HTGTPFGDIPY--GKEISYACDT--HPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRC 2290
Query: 1410 --CVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGS 1467
VP C PP +G Y + + I +G I C G W+
Sbjct: 2291 ELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQL 2350
Query: 1468 FHVCQEMQGQCSVPNELNSNLK---------------LQCPDGYAIGSECATSC 1506
H C+E+ CS P +N K L+C DGY + + C
Sbjct: 2351 DHYCKEV--NCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQC 2402
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 70.1 bits (170), Expect = 2e-11
Identities = 86/358 (24%), Positives = 134/358 (37%), Gaps = 70/358 (19%)
Query: 1196 ETYSPAEQSCVHFACEKTDCPELAVENA-SLNCSSSDRY--HGAQCTVSCRTGYVLQIRR 1252
+ +SP ++ V ++CE P + A SL+C+ + +C V ++ Q+
Sbjct: 1214 DNFSPGQE--VFYSCE----PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPH 1267
Query: 1253 DDEL--IKSQTGPSVTVTCTEG------------------KWNKQV-ACEPVDCSIPDHH 1291
L + Q G V+ C EG WN V CE + C P
Sbjct: 1268 GRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAI 1327
Query: 1292 QVYAASFSCPEGTT-FGSQCSFQCR-HPAQLKGNN----SLLTCMED----GLWSFPEAL 1341
+ P G +G + S+ C HP + N S + C D G+WS P
Sbjct: 1328 -LNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPR 1386
Query: 1342 CELM-----CLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFK 1396
CEL C P P A T + + VG+ Y+C+PGY + F
Sbjct: 1387 CELSVRAGHCKTPEQFPFAS-PTIPINDFEFPVGTSLNYECRPGYF---------GKMFS 1436
Query: 1397 TQCTQDGSWQ--EGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSN 1454
C ++ W E C +C PPP F+G+ QF S C ++ + +GS
Sbjct: 1437 ISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSC--NEGFRLIGSP 1494
Query: 1455 VIHCRKDG---TWNGSFHVCQEMQGQCSVP-----NELNSNLKLQCPDGYAIGSECAT 1504
C G TW+ +C+ + C P + SN + +G + +C T
Sbjct: 1495 STTCLVSGNNVTWDKKAPICEII--SCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 1550
Score = 57.0 bits (136), Expect = 1e-07
Identities = 81/365 (22%), Positives = 127/365 (34%), Gaps = 85/365 (23%)
Query: 1266 TVTCTEGKWNKQVACEPVD-------CSIPDHHQVYAASFSCPEGTTF--GSQCSFQCRH 1316
T+ CT V P C PDH ++A + + F G+ ++CR
Sbjct: 467 TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHF-LFAKLKTQTNASDFPIGTSLKYECR- 524
Query: 1317 PAQLKGNNSLLTCMEDGLWSFPEALCE-LMCLAPPPVPNADLQTARCRENKHKVGSFCKY 1375
+ G +TC+++ +WS P+ +C+ C PP N + +VGS Y
Sbjct: 525 -PEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVI----TDIQVGSRINY 579
Query: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDG-----SWQEGACVPVTCDPPPPKFHGLYQCTN 1430
C G+ + G S +C G S + C + C PP +G + TN
Sbjct: 580 SCTTGHRLIGHS--------SAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTN 631
Query: 1431 --GFQFNSECRIKCEDSDASQG----LGSNVIHCRKD----GTWNGSFHVCQEMQGQCSV 1480
F + S +C + +G I+C + G W+G C + +C+
Sbjct: 632 RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC-IIPNKCTP 690
Query: 1481 PN--------------ELNSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTV-RDI 1525
PN LN ++ +C G+ + C N LP V +
Sbjct: 691 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 750
Query: 1526 PHWLNPTRVER--------------------------VVCTAGLKWYPHPALIHC-VKGC 1558
P L+ R +R + CT W PA C VK C
Sbjct: 751 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDW--SPAAPTCEVKSC 808
Query: 1559 EPFMG 1563
+ FMG
Sbjct: 809 DDFMG 813
Score = 55.8 bits (133), Expect = 3e-07
Identities = 74/317 (23%), Positives = 116/317 (36%), Gaps = 56/317 (17%)
Query: 1266 TVTCTEGKWNKQVACEPVD-------CSIPDHHQVYAASFSCPEGTTF--GSQCSFQCRH 1316
T+ CT V P C PDH ++A + + F G+ ++CR
Sbjct: 917 TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHF-LFAKLKTQTNASDFPIGTSLKYECR- 974
Query: 1317 PAQLKGNNSLLTCMEDGLWSFPEALCE-LMCLAPPPVPNADLQTARCRENKHKVGSFCKY 1375
+ G +TC+++ +WS P+ +C+ C PP N + +VGS Y
Sbjct: 975 -PEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVI----TDIQVGSRINY 1029
Query: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTN--GFQ 1433
C G+ + G S + T S + C + C PP +G + TN F
Sbjct: 1030 SCTTGHRLIG---HSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFH 1086
Query: 1434 FNS----ECRIKCEDSDASQGLGSNVIHCRKD----GTWNGSFHVCQEMQGQCSVPNELN 1485
+ S C + + +G I+C + G W+G C + +C+ PN N
Sbjct: 1087 YGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC-IIPNKCTPPNVEN 1145
Query: 1486 SNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTVRDIPHWL--NPTRVERVVCTAGL 1543
L + N L V R P ++ P RV+ C A
Sbjct: 1146 GIL------------------VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK---CQALN 1184
Query: 1544 KWYPHPALIHCVKGCEP 1560
KW P L C + C+P
Sbjct: 1185 KW--EPELPSCSRVCQP 1199
Score = 54.3 bits (129), Expect = 9e-07
Identities = 58/221 (26%), Positives = 89/221 (40%), Gaps = 29/221 (13%)
Query: 1302 EGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDG---LWSFPEALCE-LMCLAPPPVPNADL 1357
+G FGSQ + C +L G++S TC+ G +W +C+ + C PP + N D
Sbjct: 119 KGIQFGSQIKYSCTKGYRLIGSSS-ATCIISGDTVIWDNETPICDRIPCGLPPTITNGDF 177
Query: 1358 QTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQ--CT----QDGSWQEGA-- 1409
+ REN H GS Y+C PG RK + + CT Q G W A
Sbjct: 178 ISTN-RENFH-YGSVVTYRCNPG----SGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 231
Query: 1410 -CVPVTCDPPPPKFHGLYQCTNG--FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNG 1466
+P C PP + +G+ N F N +C+ + G + C+ W
Sbjct: 232 CIIPNKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFVMK--GPRRVKCQALNKWEP 288
Query: 1467 SFHVCQEMQGQCSVPNE-LNSNLKLQCPDGYAIGSECATSC 1506
C + C P + L++ + D ++ G E SC
Sbjct: 289 ELPSCSRV---CQPPPDVLHAERTQRDKDNFSPGQEVFYSC 326
Score = 53.1 bits (126), Expect = 2e-06
Identities = 78/318 (24%), Positives = 121/318 (38%), Gaps = 53/318 (16%)
Query: 1210 CEKTDC--PELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTV 1267
C++ C P ++ + + ++G+ T C G R+ EL+ PS+
Sbjct: 611 CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGS--GGRKVFELVGE---PSIYC 665
Query: 1268 TCTE---GKWNKQV--ACEPVDCSIPDHHQVYAAS-----FSCPEGTTFGSQCSFQCRHP 1317
T + G W+ P C+ P+ S FS E F Q F + P
Sbjct: 666 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 725
Query: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKC 1377
++K C W C +C PP V +A+ +T R ++N G Y C
Sbjct: 726 RRVK-------CQALNKWEPELPSCSRVCQPPPDVLHAE-RTQRDKDN-FSPGQEVFYSC 776
Query: 1378 KPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNG---F 1432
+PGY + G A +CT G W A C +CD F G Q NG F
Sbjct: 777 EPGYDLRG--------AASMRCTPQGDWSPAAPTCEVKSCD----DFMG--QLLNGRVLF 822
Query: 1433 QFNSECRIKCE--DSDASQGLGSNVIHC---RKDGTWNGSFHVCQEM--QGQCSVPNELN 1485
N + K + + Q GS+ +C + WN S VC+++ +PN +
Sbjct: 823 PVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRH 882
Query: 1486 SNLKLQC-PDGYAIGSEC 1502
+ L+ P G A+ C
Sbjct: 883 TGKPLEVFPFGKAVNYTC 900
Score = 51.6 bits (122), Expect = 6e-06
Identities = 77/318 (24%), Positives = 120/318 (37%), Gaps = 53/318 (16%)
Query: 1210 CEKTDC--PELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTV 1267
C++ C P ++ + + ++G+ T C G R+ EL+ PS+
Sbjct: 161 CDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS--GGRKVFELVGE---PSIYC 215
Query: 1268 TCTE---GKWNKQV--ACEPVDCSIPDHHQVYAAS-----FSCPEGTTFGSQCSFQCRHP 1317
T + G W+ P C+ P+ S FS E F Q F + P
Sbjct: 216 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
Query: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKC 1377
++K C W C +C PP V +A+ +T R ++N G Y C
Sbjct: 276 RRVK-------CQALNKWEPELPSCSRVCQPPPDVLHAE-RTQRDKDN-FSPGQEVFYSC 326
Query: 1378 KPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNG---F 1432
+PGY + G A +CT G W A C +CD F G Q NG F
Sbjct: 327 EPGYDLRG--------AASMRCTPQGDWSPAAPTCEVKSCD----DFMG--QLLNGRVLF 372
Query: 1433 QFNSECRIKCE--DSDASQGLGSNVIHC---RKDGTWNGSFHVCQEM--QGQCSVPNELN 1485
N + K + + Q GS+ +C + WN S VC+++ +PN +
Sbjct: 373 PVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRH 432
Query: 1486 SNLKLQC-PDGYAIGSEC 1502
+ L+ P G + C
Sbjct: 433 TGKPLEVFPFGKTVNYTC 450
Score = 51.6 bits (122), Expect = 6e-06
Identities = 65/295 (22%), Positives = 101/295 (34%), Gaps = 57/295 (19%)
Query: 1235 GAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGK-WNK-QVACEPVDCSIPDHHQ 1292
G CR GY G +++C E W+ + C C P +
Sbjct: 1419 GTSLNYECRPGYF--------------GKMFSISCLENLVWSSVEDNCRRKSCGPPP--E 1462
Query: 1293 VYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDG---LWSFPEALCELMCLAP 1349
+ T FGS ++ C +L G+ S TC+ G W +CE++ P
Sbjct: 1463 PFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPST-TCLVSGNNVTWDKKAPICEIISCEP 1521
Query: 1350 PP-VPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQD--GSWQ 1406
PP + N D + R + H G+ Y+C G +R+ D G W
Sbjct: 1522 PPTISNGDFYSNN-RTSFHN-GTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWS 1579
Query: 1407 EGACVPVTCDPPPPKFHGLYQCT--------------NGFQFNSECRIKCEDSDASQGLG 1452
PPP+ +CT + F R +C+ +G
Sbjct: 1580 S----------PPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVM--VG 1627
Query: 1453 SNVIHCRKDGTWNGSFHVCQEMQGQCSVPNE-LNSNLKLQCPDGYAIGSECATSC 1506
S+ + C+ +G W C + C P E L+ L D ++ G E SC
Sbjct: 1628 SHTVQCQTNGRWGPKLPHCSRV---CQPPPEILHGEHTLSHQDNFSPGQEVFYSC 1679
Score = 46.6 bits (109), Expect = 2e-04
Identities = 35/141 (24%), Positives = 58/141 (41%), Gaps = 19/141 (13%)
Query: 1346 CLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW 1405
C AP +P A T E + +G++ Y+C+PGY R F C ++ W
Sbjct: 43 CNAPEWLPFAR-PTNLTDEFEFPIGTYLNYECRPGY---------SGRPFSIICLKNSVW 92
Query: 1406 Q--EGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDG- 1462
+ C +C PP +G+ G QF S+ + C + + +GS+ C G
Sbjct: 93 TGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSC--TKGYRLIGSSSATCIISGD 150
Query: 1463 --TWNGSFHVCQEMQGQCSVP 1481
W+ +C + C +P
Sbjct: 151 TVIWDNETPICDRI--PCGLP 169
Score = 42.0 bits (97), Expect = 0.005
Identities = 55/234 (23%), Positives = 81/234 (34%), Gaps = 35/234 (14%)
Query: 1301 PEGTTFGSQCSFQCRHPAQLKGNNS---LLTCMEDGLWSFPEALCE-LMCLAPPPVPNAD 1356
P G++ SF C +LKG ++ +L M+ LW+ +CE + C PP + N
Sbjct: 1726 PLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMK-ALWNSSVPVCEQIFCPNPPAILNGR 1784
Query: 1357 LQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQD----GSWQEGA--- 1409
+ + G Y C H + +CT D G W A
Sbjct: 1785 HTGTPFGDIPY--GKEISYACDT--HPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRC 1840
Query: 1410 --CVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGS 1467
VP C PP +G Y + + I +G I C G W+
Sbjct: 1841 ELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQL 1900
Query: 1468 FHVCQEMQGQCSVPNELNSNLK---------------LQCPDGYAIGSECATSC 1506
H C+E+ CS P +N K L+C DGY + + C
Sbjct: 1901 DHYCKEV--NCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQC 1952
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 63.9 bits (154), Expect = 1e-09
Identities = 78/347 (22%), Positives = 121/347 (34%), Gaps = 67/347 (19%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCR-TGYVLQI 1250
C+ T+ P CEK C + L S C + TG+ Q+
Sbjct: 644 CKADNTWDPEIP-----VCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQM 698
Query: 1251 RRDDELIKSQTGPSVTVTCTEGKWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTFGSQ 1309
+D E G W K++ C+ + C P + E +G++
Sbjct: 699 CQDAE---------------NGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNE 743
Query: 1310 CSFQCRHPAQLKGNNSLLTCMED----GLWSFPEALCELMCLAPPPV---PNADLQTARC 1362
S++C L G L C D G WS P CL PPV PN +++
Sbjct: 744 VSYECDQGFYLLGEKKL-QCRSDSKGHGSWSGPSP----QCLRSPPVTRCPNPEVKHGYK 798
Query: 1363 RENKHKVGS---FCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVP---VT 1414
H S C PG+ + GS +C D +W G C+ +
Sbjct: 799 LNKTHSAYSHNDIVYVDCNPGFIMNGSR--------VIRCHTDNTWVPGVPTCIKKAFIG 850
Query: 1415 CDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEM 1474
C PPP +G + N +F+ I +G ++ C +GTW+ C+E+
Sbjct: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEV 910
Query: 1475 QGQCSVPNELNSNLK---------------LQCPDGYAIGSECATSC 1506
CS P +++ K L+C DGY + + C
Sbjct: 911 --NCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC 955
Score = 55.5 bits (132), Expect = 4e-07
Identities = 71/331 (21%), Positives = 119/331 (35%), Gaps = 44/331 (13%)
Query: 1197 TYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDEL 1256
T+ C +F + + CPE V S+ HG T +C+T + + +
Sbjct: 74 TWDKPAPKCEYFN-KYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC 132
Query: 1257 -IKSQTGPSVTVTCTEGKWNKQVACEPVDC-SIPDHHQVYAASFSCPEGTTFGSQCSFQC 1314
+ GP+ TC V+ P++C ++P H + S + G ++ C
Sbjct: 133 QANNMWGPTRLPTC--------VSVFPLECPALPMIHNGHHTSENV-GSIAPGLSVTYSC 183
Query: 1315 RHPAQLKGNNSLLTCMEDGLWSFPEALC-ELMCLAPPPVPNADLQTARCRENKHKVGSFC 1373
L G ++ C+ G WS C E C + PN ++ +VG
Sbjct: 184 ESGYLLVG-EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPIL----RVGVTA 238
Query: 1374 KYKCKPGYHVPGSSRKSKKRAFKTQCT---QDGSWQE-GACVPVTCDPPPPKFHGLY--Q 1427
+ C GY + G ++C Q +W + C + C PPP +G +
Sbjct: 239 NFFCDEGYRLQGPP--------SSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGN 290
Query: 1428 CTNGFQFNSECRIKCEDSDASQG-----LGSNVIHC----RKDGTWNGSFHVCQEMQG-- 1476
+ S C D D +G +G + + C +K GTW+G C+
Sbjct: 291 SLANVSYGSIVTYTC-DPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAV 349
Query: 1477 QCSVPNELNSNLKLQCPDGYAIGSECATSCL 1507
QC P L + D Y +C+
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACM 380
Score = 53.9 bits (128), Expect = 1e-06
Identities = 62/278 (22%), Positives = 96/278 (34%), Gaps = 57/278 (20%)
Query: 1215 CPELAVENA-SLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGK 1273
C + + N ++ + ++ T C +G+ L+ G S +
Sbjct: 602 CSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLK------------GSSQIRCKADNT 649
Query: 1274 WNKQV-ACEPVDCS--------IPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNN 1324
W+ ++ CE C +P +V + SC +G C+
Sbjct: 650 WDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA------- 702
Query: 1325 SLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVP 1384
E+G+W LC+++ PPPV T EN G+ Y+C G+++
Sbjct: 703 ------ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN-FLYGNEVSYECDQGFYLL 755
Query: 1385 GSSRKSKKRAFKTQCTQD----GSWQ--EGACV---PVTCDPPPPKFHG--LYQCTNGFQ 1433
G K QC D GSW C+ PVT P P HG L + + +
Sbjct: 756 GEK--------KLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYS 807
Query: 1434 FNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVC 1471
N + C GS VI C D TW C
Sbjct: 808 HNDIVYVDCNPGFIMN--GSRVIRCHTDNTWVPGVPTC 843
Score = 52.0 bits (123), Expect = 5e-06
Identities = 32/105 (30%), Positives = 43/105 (40%), Gaps = 19/105 (18%)
Query: 1305 TFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRE 1364
T+ F C LKG+ + C G W +CE C APP + N +E
Sbjct: 370 TYNDTVIFACMFGFTLKGSKQI-RCNAQGTWEPSAPVCEKECQAPPNILNGQ------KE 422
Query: 1365 NKHKV----GSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW 1405
++H V G+ KY C PGY + G QCT +G W
Sbjct: 423 DRHMVRFDPGTSIKYSCNPGYVLVGEE--------SIQCTSEGVW 459
Score = 45.1 bits (105), Expect = 6e-04
Identities = 75/390 (19%), Positives = 126/390 (32%), Gaps = 87/390 (22%)
Query: 1192 CQRGETYSPAE-QSCVHFACEKTDCPELAVENASLNCSSS--DRYHGAQCTVSCRTGYVL 1248
CQ + P +CV + +CP L + + + S + G T SC +GY+L
Sbjct: 132 CQANNMWGPTRLPTCV--SVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLL 189
Query: 1249 QIRRDDELIKSQTGPSVTVTCTEGK----------------------------------- 1273
+ + S +V TC E +
Sbjct: 190 VGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ 249
Query: 1274 ---------------WNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPA 1318
W K CE + C P + ++GS ++ C P
Sbjct: 250 GPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTC-DPD 308
Query: 1319 QLKGNN------SLLTCMED----GLWSFPEALCELMCLAPPPVPNADLQTARC---REN 1365
+G N S L C D G WS P CEL A P+ + R +++
Sbjct: 309 PEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSA-VQCPHPQILRGRMVSGQKD 367
Query: 1366 KHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACV-PVTCDPPPPKFHG 1424
++ + C G+ + GS + +C G+W+ A V C PP +G
Sbjct: 368 RYTYNDTVIFACMFGFTLKGSK--------QIRCNAQGTWEPSAPVCEKECQAPPNILNG 419
Query: 1425 LYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ----EMQGQCSV 1480
+ + +F+ IK + +G I C +G W C+ E G+ +
Sbjct: 420 QKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLL 479
Query: 1481 PNE----LNSNLKLQCPDGYAIGSECATSC 1506
+ ++ C +GY + C
Sbjct: 480 TKPQHQFVRPDVNSSCGEGYKLSGSVYQEC 509
Score = 45.1 bits (105), Expect = 6e-04
Identities = 56/280 (20%), Positives = 94/280 (33%), Gaps = 41/280 (14%)
Query: 1210 CEKTDC--PELAVENASLNCSSSDRYHGAQCTVSCRTGYVL------QIRRDDELIKSQT 1261
C+ C P + V + + +G + + C G+ L Q R D + S +
Sbjct: 714 CKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 773
Query: 1262 GPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLK 1321
GPS Q P P+ + + + + +P +
Sbjct: 774 GPS-----------PQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 822
Query: 1322 GNNSLLTCMEDGLWSFPEALCE----LMCLAPPPVPNADLQTARCRENKHKVGSFCKYKC 1377
+ ++ C D W C + C PP PN + + G Y C
Sbjct: 823 NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIA--RFSPGMSILYSC 880
Query: 1378 KPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNG---F 1432
GY + G + CT +G+W + A C V C P G+ + +
Sbjct: 881 DQGYLLVGEAL--------LLCTHEGTWSQPAPHCKEVNCSSPAD-MDGIQKGLEPRKMY 931
Query: 1433 QFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
Q+ + ++CED +G S C+ D WN VC+
Sbjct: 932 QYGAVVTLECEDGYMLEG--SPQSQCQSDHQWNPPLAVCR 969
Score = 42.4 bits (98), Expect = 0.004
Identities = 49/212 (23%), Positives = 76/212 (35%), Gaps = 28/212 (13%)
Query: 1213 TDCPELAVENA-SLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTE 1271
T CP V++ LN + S H V C G+++ R T TC +
Sbjct: 786 TRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIK 845
Query: 1272 GKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCME 1331
+ + C P + +H + P G + C L G +LL C
Sbjct: 846 KAF---IGCPPPPKTPNGNHTGGNIARFSP-----GMSILYSCDQGYLLVGE-ALLLCTH 896
Query: 1332 DGLWSFPEALC-ELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKS 1390
+G WS P C E+ C +P + +Q ++ G+ +C+ GY + GS
Sbjct: 897 EGTWSQPAPHCKEVNCSSPADMDG--IQKGLEPRKMYQYGAVVTLECEDGYMLEGSP--- 951
Query: 1391 KKRAFKTQCTQDGSWQEGACV-------PVTC 1415
++QC D W V PV C
Sbjct: 952 -----QSQCQSDHQWNPPLAVCRSRSLAPVLC 978
Score = 41.2 bits (95), Expect = 0.008
Identities = 83/364 (22%), Positives = 115/364 (31%), Gaps = 102/364 (28%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYH-----GAQCTVSCRTGY 1246
C T+ P+ CEK E LN DR+ G SC GY
Sbjct: 393 CNAQGTWEPSAP-----VCEK----ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
Query: 1247 VLQIRRDDELIKSQTGPSVTVTCTEGKWN------KQVACEPVDCSI---PDHHQVYA-A 1296
VL G +EG W K ACE + P H V
Sbjct: 444 VL------------VGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDV 491
Query: 1297 SFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNAD 1356
+ SC EG +C+ W LC+ + PPPV
Sbjct: 492 NSSCGEGYKLSGSVYQECQGTIP---------------WFMEIRLCKEITCPPPPVIYNG 536
Query: 1357 LQTARCRENKHKVGSFCKYKCKPG------YHVPGSSRKSKKRAFKTQCTQD----GSWQ 1406
T E+ G+ Y C PG + + G S +CT + G+W
Sbjct: 537 AHTGSSLED-FPYGTTVTYTCNPGPERGVEFSLIGEST--------IRCTSNDQERGTWS 587
Query: 1407 EGACVPVTCDPPPPKFHGL-YQCT-----NGFQ---------FNSECRIKCEDSDASQGL 1451
A P K L QC+ NG++ +N KC +G
Sbjct: 588 GPA--------PLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG- 638
Query: 1452 GSNVIHCRKDGTWNGSFHVCQE--MQGQCSVPNELNSNLKLQ-----CPDGYAIGSECAT 1504
S+ I C+ D TW+ VC++ Q EL + +++ C DGY +
Sbjct: 639 -SSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQ 697
Query: 1505 SCLD 1508
C D
Sbjct: 698 MCQD 701
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 62.4 bits (150), Expect = 3e-09
Identities = 66/253 (26%), Positives = 100/253 (39%), Gaps = 46/253 (18%)
Query: 1235 GAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTC-TEGKWNKQVACEPVDCSIPDHHQV 1293
G +C GYV ++ + T+TC ++G+W C C P ++
Sbjct: 74 GTTLKYTCLPGYV------------RSHSTQTLTCNSDGEWVYNTFCIYKRCRHPG--EL 119
Query: 1294 YAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMED-GL-WSFPEALCELMCLAPPP 1351
+FGSQ F C L G+ + ++D G+ WS P CE++ PPP
Sbjct: 120 RNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPP 179
Query: 1352 VPNADLQTARC--RENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQD----GSW 1405
D++ R EN + G Y C P + + G + S CT + G W
Sbjct: 180 ----DIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASIS--------CTVENETIGVW 227
Query: 1406 QEG--ACVPVTCDPPPPKFHGLYQCTNGF----QFNSECRIKCEDSDASQGLGSNVIHCR 1459
+ C +TC P HG + +GF + KC+ +G S+VIHC
Sbjct: 228 RPSPPTCEKITCRKPDVS-HG--EMVSGFGPIYNYKDTIVFKCQKGFVLRG--SSVIHCD 282
Query: 1460 KDGTWNGSFHVCQ 1472
D WN S C+
Sbjct: 283 ADSKWNPSPPACE 295
Score = 53.5 bits (127), Expect = 2e-06
Identities = 64/332 (19%), Positives = 113/332 (34%), Gaps = 75/332 (22%)
Query: 1270 TEGKWNKQV-ACEPVDCSIPD-HHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLL 1327
T G W CE + C PD H + F + F+C+ L+G+ S++
Sbjct: 223 TIGVWRPSPPTCEKITCRKPDVSHGEMVSGFG--PIYNYKDTIVFKCQKGFVLRGS-SVI 279
Query: 1328 TCMEDGLWSFPEALCEL-MCLAPPPVPNADLQT--ARCRENKHKVGSFCKYKCKPGYHVP 1384
C D W+ CE C+ P +P+A +T +E+ + VG+ +Y+C PGY
Sbjct: 280 HCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGY--- 336
Query: 1385 GSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHG----------LYQCTNGFQF 1434
+ + C ++ W C P P +G C + +
Sbjct: 337 ---KPTTDEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCV--YFY 391
Query: 1435 NSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNEL---------- 1484
E C ++ + C+ DGTW+ C ++ C+ P ++
Sbjct: 392 GDEISFSCHETSRFSAI------CQGDGTWSPRTPSCGDI---CNFPPKIAHGHYKQSSS 442
Query: 1485 ----NSNLKLQCPDGYAIGSECATSC-------------------------LDHNSESII 1515
+ +C GY + + SC L + + +
Sbjct: 443 YSFFKEEIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPELVNGRLSVDKDQYV 502
Query: 1516 LPMNVTVRDIPHWLNPTRVERVVCTAGLKWYP 1547
P NVT++ + + C+ WYP
Sbjct: 503 EPENVTIQ-CDSGYGVVGPQSITCSGNRTWYP 533
Score = 44.3 bits (103), Expect = 0.001
Identities = 40/166 (24%), Positives = 57/166 (34%), Gaps = 17/166 (10%)
Query: 1346 CLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQ---CTQD 1402
C PP + A E + K G+ KY C PGY R+ TQ C D
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGY----------VRSHSTQTLTCNSD 99
Query: 1403 GSWQEGA-CVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKD 1461
G W C+ C P +G + F S+ C S+ +GS C
Sbjct: 100 GEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSC--SEGFFLIGSTTSRCEVQ 157
Query: 1462 GTWNGSFHVCQEMQ-GQCSVPNELNSNLKLQCPDGYAIGSECATSC 1506
G H + + +C P ++ + + YA G SC
Sbjct: 158 DRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSC 203
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 62.0 bits (149), Expect = 5e-09
Identities = 79/350 (22%), Positives = 124/350 (35%), Gaps = 74/350 (21%)
Query: 1192 CQRGETYSPA----EQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYV 1247
C +SP+ E++C H + P +N S D Y TG+
Sbjct: 704 CMPSGNWSPSAPRCEETCQHVRQSLQELPA-GSRVELVNTSCQDGYQ--------LTGHA 754
Query: 1248 LQIRRDDELIKSQTGPSVTVTCTEGKWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTF 1306
Q+ +D E G W K++ C+ + C P + E +
Sbjct: 755 YQMCQDAE---------------NGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLY 799
Query: 1307 GSQCSFQCRHPAQLKGNNSLLTCMED----GLWSFPEALCELMCLAPPPV---PNADLQT 1359
G++ S++C L G L C D G WS P CL PPV PN +++
Sbjct: 800 GNEVSYECDQGFYLLGEKKL-QCRSDSKGHGSWSGPSP----QCLRSPPVTRCPNPEVKH 854
Query: 1360 ARCRENKHKVGS---FCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVP-- 1412
H S C PG+ + GS +C D +W G C+
Sbjct: 855 GYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR--------VIRCHTDNTWVPGVPTCIKKA 906
Query: 1413 -VTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVC 1471
+ C PPP +G + N +F+ I +G ++ C +GTW+ C
Sbjct: 907 FIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC 966
Query: 1472 QEMQGQCSVPNELNSNLK---------------LQCPDGYAIGSECATSC 1506
+E+ CS P +++ K L+C DGY + + C
Sbjct: 967 KEV--NCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC 1014
Score = 58.9 bits (141), Expect = 4e-08
Identities = 78/330 (23%), Positives = 121/330 (36%), Gaps = 56/330 (16%)
Query: 1220 VENASLNCSSSDRYHGA--QCTVSC--RTGYVLQIRRDDELIKSQTGPSVTVTCTEG--- 1272
V S+ C+S + QC V+ TG L + + ++ P V +C EG
Sbjct: 446 VGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR----PDVNSSCGEGYKL 501
Query: 1273 ------------KWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQ 1319
W ++ C+ + C P A + S E +G+ ++ C +P
Sbjct: 502 SGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTC-NPGP 560
Query: 1320 LKG------NNSLLTC----MEDGLWSFPEALCELMCLAPP--PVPNADLQTARCRENKH 1367
+G S + C E G WS P LC+L LA V A+ +E +
Sbjct: 561 ERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPY 620
Query: 1368 KVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVT---CDPPPPKFHG 1424
+KC G+ + GSS+ +C D +W +PV C PP HG
Sbjct: 621 FYNDTVTFKCYSGFTLKGSSQ--------IRCKADNTWDPE--IPVCEKGCQSPPGLHHG 670
Query: 1425 LYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQE-MQGQCSVPNE 1483
+ N F S + +G+ IHC G W+ S C+E Q E
Sbjct: 671 RHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQE 730
Query: 1484 LNSNLKLQ-----CPDGYAIGSECATSCLD 1508
L + +++ C DGY + C D
Sbjct: 731 LPAGSRVELVNTSCQDGYQLTGHAYQMCQD 760
Score = 55.5 bits (132), Expect = 4e-07
Identities = 71/331 (21%), Positives = 119/331 (35%), Gaps = 44/331 (13%)
Query: 1197 TYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDEL 1256
T+ C +F + + CPE V S+ HG T +C+T + + +
Sbjct: 74 TWDKPAPKCEYFN-KYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC 132
Query: 1257 -IKSQTGPSVTVTCTEGKWNKQVACEPVDC-SIPDHHQVYAASFSCPEGTTFGSQCSFQC 1314
+ GP+ TC V+ P++C ++P H + S + G ++ C
Sbjct: 133 QANNMWGPTRLPTC--------VSVFPLECPALPMIHNGHHTSENV-GSIAPGLSVTYSC 183
Query: 1315 RHPAQLKGNNSLLTCMEDGLWSFPEALC-ELMCLAPPPVPNADLQTARCRENKHKVGSFC 1373
L G ++ C+ G WS C E C + PN ++ +VG
Sbjct: 184 ESGYLLVG-EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPIL----RVGVTA 238
Query: 1374 KYKCKPGYHVPGSSRKSKKRAFKTQCT---QDGSWQE-GACVPVTCDPPPPKFHGLY--Q 1427
+ C GY + G ++C Q +W + C + C PPP +G +
Sbjct: 239 NFFCDEGYRLQGPP--------SSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGN 290
Query: 1428 CTNGFQFNSECRIKCEDSDASQG-----LGSNVIHC----RKDGTWNGSFHVCQEMQG-- 1476
+ S C D D +G +G + + C +K GTW+G C+
Sbjct: 291 SLANVSYGSIVTYTC-DPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAV 349
Query: 1477 QCSVPNELNSNLKLQCPDGYAIGSECATSCL 1507
QC P L + D Y +C+
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACM 380
Score = 53.1 bits (126), Expect = 2e-06
Identities = 80/327 (24%), Positives = 109/327 (33%), Gaps = 65/327 (19%)
Query: 1173 ISGVALRSFDNFDPVTLSSCQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDR 1232
ISG F N D VT C G T + Q + + T PE+ V C S
Sbjct: 613 ISGKEAPYFYN-DTVTFK-CYSGFTLKGSSQ--IRCKADNTWDPEIPV--CEKGCQSPPG 666
Query: 1233 YH--------------GAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQV 1278
H G +C GY+L + + S C E
Sbjct: 667 LHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE------- 719
Query: 1279 ACEPVDCSI---PDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLW 1335
C+ V S+ P +V + SC +G C+ E+G+W
Sbjct: 720 TCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA-------------ENGIW 766
Query: 1336 SFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAF 1395
LC+++ PPPV T EN G+ Y+C G+++ G
Sbjct: 767 FKKIPLCKVIHCHPPPVIVNGKHTGMMAEN-FLYGNEVSYECDQGFYLLGEK-------- 817
Query: 1396 KTQCTQD----GSWQ--EGACV---PVTCDPPPPKFHG--LYQCTNGFQFNSECRIKCED 1444
K QC D GSW C+ PVT P P HG L + + + N + C
Sbjct: 818 KLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNP 877
Query: 1445 SDASQGLGSNVIHCRKDGTWNGSFHVC 1471
GS VI C D TW C
Sbjct: 878 GFIMN--GSRVIRCHTDNTWVPGVPTC 902
Score = 52.0 bits (123), Expect = 5e-06
Identities = 32/105 (30%), Positives = 43/105 (40%), Gaps = 19/105 (18%)
Query: 1305 TFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRE 1364
T+ F C LKG+ + C G W +CE C APP + N +E
Sbjct: 370 TYNDTVIFACMFGFTLKGSKQI-RCNAQGTWEPSAPVCEKECQAPPNILNGQ------KE 422
Query: 1365 NKHKV----GSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW 1405
++H V G+ KY C PGY + G QCT +G W
Sbjct: 423 DRHMVRFDPGTSIKYSCNPGYVLVGEE--------SIQCTSEGVW 459
Score = 45.1 bits (105), Expect = 6e-04
Identities = 75/390 (19%), Positives = 126/390 (32%), Gaps = 87/390 (22%)
Query: 1192 CQRGETYSPAE-QSCVHFACEKTDCPELAVENASLNCSSS--DRYHGAQCTVSCRTGYVL 1248
CQ + P +CV + +CP L + + + S + G T SC +GY+L
Sbjct: 132 CQANNMWGPTRLPTCV--SVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLL 189
Query: 1249 QIRRDDELIKSQTGPSVTVTCTEGK----------------------------------- 1273
+ + S +V TC E +
Sbjct: 190 VGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ 249
Query: 1274 ---------------WNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPA 1318
W K CE + C P + ++GS ++ C P
Sbjct: 250 GPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTC-DPD 308
Query: 1319 QLKGNN------SLLTCMED----GLWSFPEALCELMCLAPPPVPNADLQTARC---REN 1365
+G N S L C D G WS P CEL A P+ + R +++
Sbjct: 309 PEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSA-VQCPHPQILRGRMVSGQKD 367
Query: 1366 KHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACV-PVTCDPPPPKFHG 1424
++ + C G+ + GS + +C G+W+ A V C PP +G
Sbjct: 368 RYTYNDTVIFACMFGFTLKGSK--------QIRCNAQGTWEPSAPVCEKECQAPPNILNG 419
Query: 1425 LYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ----EMQGQCSV 1480
+ + +F+ IK + +G I C +G W C+ E G+ +
Sbjct: 420 QKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLL 479
Query: 1481 PNE----LNSNLKLQCPDGYAIGSECATSC 1506
+ ++ C +GY + C
Sbjct: 480 TKPQHQFVRPDVNSSCGEGYKLSGSVYQEC 509
Score = 45.1 bits (105), Expect = 6e-04
Identities = 56/280 (20%), Positives = 94/280 (33%), Gaps = 41/280 (14%)
Query: 1210 CEKTDC--PELAVENASLNCSSSDRYHGAQCTVSCRTGYVL------QIRRDDELIKSQT 1261
C+ C P + V + + +G + + C G+ L Q R D + S +
Sbjct: 773 CKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 832
Query: 1262 GPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLK 1321
GPS Q P P+ + + + + +P +
Sbjct: 833 GPS-----------PQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 881
Query: 1322 GNNSLLTCMEDGLWSFPEALCE----LMCLAPPPVPNADLQTARCRENKHKVGSFCKYKC 1377
+ ++ C D W C + C PP PN + + G Y C
Sbjct: 882 NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIA--RFSPGMSILYSC 939
Query: 1378 KPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNG---F 1432
GY + G + CT +G+W + A C V C P G+ + +
Sbjct: 940 DQGYLLVGEAL--------LLCTHEGTWSQPAPHCKEVNCSSPAD-MDGIQKGLEPRKMY 990
Query: 1433 QFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
Q+ + ++CED +G S C+ D WN VC+
Sbjct: 991 QYGAVVTLECEDGYMLEG--SPQSQCQSDHQWNPPLAVCR 1028
Score = 42.4 bits (98), Expect = 0.004
Identities = 49/212 (23%), Positives = 76/212 (35%), Gaps = 28/212 (13%)
Query: 1213 TDCPELAVENA-SLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTE 1271
T CP V++ LN + S H V C G+++ R T TC +
Sbjct: 845 TRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIK 904
Query: 1272 GKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCME 1331
+ + C P + +H + P G + C L G +LL C
Sbjct: 905 KAF---IGCPPPPKTPNGNHTGGNIARFSP-----GMSILYSCDQGYLLVGE-ALLLCTH 955
Query: 1332 DGLWSFPEALC-ELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKS 1390
+G WS P C E+ C +P + +Q ++ G+ +C+ GY + GS
Sbjct: 956 EGTWSQPAPHCKEVNCSSPADMDG--IQKGLEPRKMYQYGAVVTLECEDGYMLEGSP--- 1010
Query: 1391 KKRAFKTQCTQDGSWQEGACV-------PVTC 1415
++QC D W V PV C
Sbjct: 1011 -----QSQCQSDHQWNPPLAVCRSRSLAPVLC 1037
Score = 37.7 bits (86), Expect = 0.091
Identities = 74/322 (22%), Positives = 101/322 (31%), Gaps = 95/322 (29%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYH-----GAQCTVSCRTGY 1246
C T+ P+ CEK E LN DR+ G SC GY
Sbjct: 393 CNAQGTWEPSAP-----VCEK----ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
Query: 1247 VLQIRRDDELIKSQTGPSVTVTCTEGKWN------KQVACEPVDCSI---PDHHQVYA-A 1296
VL G +EG W K ACE + P H V
Sbjct: 444 VL------------VGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDV 491
Query: 1297 SFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNAD 1356
+ SC EG +C+ W LC+ + PPPV
Sbjct: 492 NSSCGEGYKLSGSVYQECQGTIP---------------WFMEIRLCKEITCPPPPVIYNG 536
Query: 1357 LQTARCRENKHKVGSFCKYKCKPG------YHVPGSSRKSKKRAFKTQCTQD----GSWQ 1406
T E+ G+ Y C PG + + G S +CT + G+W
Sbjct: 537 AHTGSSLED-FPYGTTVTYTCNPGPERGVEFSLIGEST--------IRCTSNDQERGTWS 587
Query: 1407 EGACVPVTCDPPPPKFHGL-YQCT-----NGFQ---------FNSECRIKCEDSDASQGL 1451
A P K L QC+ NG++ +N KC +G
Sbjct: 588 GPA--------PLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG- 638
Query: 1452 GSNVIHCRKDGTWNGSFHVCQE 1473
S+ I C+ D TW+ VC++
Sbjct: 639 -SSQIRCKADNTWDPEIPVCEK 659
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 60.5 bits (145), Expect = 1e-08
Identities = 48/225 (21%), Positives = 82/225 (36%), Gaps = 18/225 (8%)
Query: 1287 IPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMC 1346
+P+ S PE T +C ++ G + C++ WS E C C
Sbjct: 42 VPNAQPALEGRTSFPEDTVITYKCEESF---VKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
Query: 1347 LAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQ 1406
P + +A L+ +N VG+ +Y+C+PGY R+ + K C Q+ W
Sbjct: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGY------RREPSLSPKLTCLQNLKWS 152
Query: 1407 EGA--CVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGT- 1463
C +C P +G G F + C + + GS C G+
Sbjct: 153 TAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSC--NTGYKLFGSTSSFCLISGSS 210
Query: 1464 --WNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSECATSC 1506
W+ C+E+ C P ++++ + D Y +C
Sbjct: 211 VQWSDPLPECREI--YCPAPPQIDNGIIQGERDHYGYRQSVTYAC 253
Score = 51.6 bits (122), Expect = 6e-06
Identities = 62/242 (25%), Positives = 94/242 (38%), Gaps = 46/242 (19%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYH---GAQCTVSCRTGYVL 1248
C +G +S E+ C + +CE + +ASL + + G CR GY
Sbjct: 81 CLKGSQWSDIEEFC-NRSCEVPT----RLNSASLKQPYITQNYFPVGTVVEYECRPGY-- 133
Query: 1249 QIRRDDELIKSQTGPSVTVTCTEG-KWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTF 1306
RR+ L S +TC + KW+ V C+ C P+ ++ P G F
Sbjct: 134 --RREPSL-------SPKLTCLQNLKWSTAVEFCKKKSC--PNPGEIRNGQIDVPGGILF 182
Query: 1307 GSQCSFQCRHPAQLKGNNSLLTCMEDG---LWSFPEALC-ELMCLAPPPVPNADLQTARC 1362
G+ SF C +L G+ S C+ G WS P C E+ C APP + N +Q R
Sbjct: 183 GATISFSCNTGYKLFGSTSSF-CLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER- 240
Query: 1363 RENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKF 1422
+ + Y C G+ + G + + T +G W PPP+
Sbjct: 241 --DHYGYRQSVTYACNKGFTMIG-----EHSIYCTVNNDEGEW----------SGPPPEC 283
Query: 1423 HG 1424
G
Sbjct: 284 RG 285
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 60.5 bits (145), Expect = 1e-08
Identities = 48/225 (21%), Positives = 82/225 (36%), Gaps = 18/225 (8%)
Query: 1287 IPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMC 1346
+P+ S PE T +C ++ G + C++ WS E C C
Sbjct: 42 VPNAQPALEGRTSFPEDTVITYKCEESF---VKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
Query: 1347 LAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQ 1406
P + +A L+ +N VG+ +Y+C+PGY R+ + K C Q+ W
Sbjct: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGY------RREPSLSPKLTCLQNLKWS 152
Query: 1407 EGA--CVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGT- 1463
C +C P +G G F + C + + GS C G+
Sbjct: 153 TAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSC--NTGYKLFGSTSSFCLISGSS 210
Query: 1464 --WNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSECATSC 1506
W+ C+E+ C P ++++ + D Y +C
Sbjct: 211 VQWSDPLPECREI--YCPAPPQIDNGIIQGERDHYGYRQSVTYAC 253
Score = 51.6 bits (122), Expect = 6e-06
Identities = 62/242 (25%), Positives = 94/242 (38%), Gaps = 46/242 (19%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYH---GAQCTVSCRTGYVL 1248
C +G +S E+ C + +CE + +ASL + + G CR GY
Sbjct: 81 CLKGSQWSDIEEFC-NRSCEVPT----RLNSASLKQPYITQNYFPVGTVVEYECRPGY-- 133
Query: 1249 QIRRDDELIKSQTGPSVTVTCTEG-KWNKQVA-CEPVDCSIPDHHQVYAASFSCPEGTTF 1306
RR+ L S +TC + KW+ V C+ C P+ ++ P G F
Sbjct: 134 --RREPSL-------SPKLTCLQNLKWSTAVEFCKKKSC--PNPGEIRNGQIDVPGGILF 182
Query: 1307 GSQCSFQCRHPAQLKGNNSLLTCMEDG---LWSFPEALC-ELMCLAPPPVPNADLQTARC 1362
G+ SF C +L G+ S C+ G WS P C E+ C APP + N +Q R
Sbjct: 183 GATISFSCNTGYKLFGSTSSF-CLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER- 240
Query: 1363 RENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKF 1422
+ + Y C G+ + G + + T +G W PPP+
Sbjct: 241 --DHYGYRQSVTYACNKGFTMIG-----EHSIYCTVNNDEGEW----------SGPPPEC 283
Query: 1423 HG 1424
G
Sbjct: 284 RG 285
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 58.9 bits (141), Expect = 4e-08
Identities = 74/348 (21%), Positives = 131/348 (37%), Gaps = 61/348 (17%)
Query: 1190 SSCQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRY-HGAQCTVSCRTGYVL 1248
++C G+ SP + CE C + + SD Y +G + T C G+ +
Sbjct: 913 TTCYMGKWSSPPQ-------CEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGI 965
Query: 1249 QIRRDDELIKSQTGPSVTVTCTEGKWNKQVACEPVDC-SIPDHHQVYAASFSCPEGTTFG 1307
GP++ C KW+ +C DC S+P + G
Sbjct: 966 D------------GPAIA-KCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEK-KDVYKAG 1011
Query: 1308 SQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKH 1367
Q ++ C ++ G +++ TC+ + W+ + C+ PP V NA + + + +K+
Sbjct: 1012 EQVTYTCATYYKMDGASNV-TCI-NSRWTGRPTCRDTSCVNPPTVQNAYIVSRQM--SKY 1067
Query: 1368 KVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA-CVPVT--CDPPPPKFHG 1424
G +Y+C+ Y + G + C +G+W E C T C PPPP +G
Sbjct: 1068 PSGERVRYQCRSPYEMFGDE--------EVMCL-NGNWTEPPQCKDSTGKCGPPPPIDNG 1118
Query: 1425 ----------------LYQCTNGFQFNSECRIKCEDSDASQGLGSNVIH-CRKDGTWNGS 1467
YQC N +Q RI C + S+ +H C +
Sbjct: 1119 DITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSE--PPKCLHPCVISREIMEN 1176
Query: 1468 FHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSE---CATSCLDHNSE 1512
+++ + + + +++ C GY + S T+C D E
Sbjct: 1177 YNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLRTTCWDGKLE 1224
Score = 55.1 bits (131), Expect = 6e-07
Identities = 78/331 (23%), Positives = 121/331 (36%), Gaps = 68/331 (20%)
Query: 1210 CEKTDC-PELAVENASLNCSSSD---RYHGAQCT-VSCRTGYVLQIRRDDELIKSQTGPS 1264
CE C P A EN + S+ + YH Q C +GY +I D+E+ S
Sbjct: 141 CEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGY--KIEGDEEMHCSD---- 194
Query: 1265 VTVTCTEGKWNKQVA-CEPVDCSIPD--HHQVYAASFSCPEGTTFGSQCSFQCRHPAQLK 1321
+G W+K+ C + C PD + + E F +C+ + +
Sbjct: 195 ------DGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSE--R 246
Query: 1322 GNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGY 1381
G+ C E G P CE P +PN D R KH+ G Y+C+ G+
Sbjct: 247 GD---AVCTESGWRPLPS--CEEKSCDNPYIPNGDYSPLRI---KHRTGDEITYQCRNGF 298
Query: 1382 HVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQ---------CTNGF 1432
+ +K CT G C CD P K GLY G
Sbjct: 299 YPATRGNTAK-------CTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGK 351
Query: 1433 QFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVP---NELNSN-- 1487
++ C E + G + IHC +DG W+ + + +C P N N N
Sbjct: 352 YYSYYCD---EHFETPSGSYWDHIHCTQDG-WSPAVPCLR----KCYFPYLENGYNQNHG 403
Query: 1488 --------LKLQCPDGYAI-GSECATSCLDH 1509
+ + C GYA+ ++ +C+++
Sbjct: 404 RKFVQGKSIDVACHPGYALPKAQTTVTCMEN 434
Score = 53.1 bits (126), Expect = 2e-06
Identities = 41/188 (21%), Positives = 75/188 (39%), Gaps = 26/188 (13%)
Query: 1265 VTVTCTEGKWNKQVACE-------PVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHP 1317
+ C G+W+ +V C P IP+ H + G + S C+
Sbjct: 788 IHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTL-----NYRDGEKVSVLCQEN 842
Query: 1318 AQLKGNNSLLTCMEDGLW-SFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYK 1376
++ + TC +DG W S P + ++ C PP + + + ++R + + G+ Y
Sbjct: 843 YLIQEGEEI-TC-KDGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYT 900
Query: 1377 CKPGYHVPGSSRKSKKRAFKTQCTQDGSWQE-GACVPVTCDPPPPKFHGLY-QCTNGFQF 1434
C+ G+ + + +T C G W C + C PP HG+ ++ +Q+
Sbjct: 901 CEGGFRISEEN--------ETTCYM-GKWSSPPQCEGLPCKSPPEISHGVVAHMSDSYQY 951
Query: 1435 NSECRIKC 1442
E KC
Sbjct: 952 GEEVTYKC 959
Score = 44.3 bits (103), Expect = 0.001
Identities = 69/328 (21%), Positives = 102/328 (31%), Gaps = 92/328 (28%)
Query: 1214 DCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGK 1273
D PEL E+ SS Y+G +C + + R ++TC G
Sbjct: 693 DIPEL--EHGWAQLSSPPYYYGDSVEFNCSESFTMIGHR-------------SITCIHGV 737
Query: 1274 WNKQVACEPVD----CS-----IPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNN 1324
W + C +D C I + H F S ++CR
Sbjct: 738 WTQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFD------HNSNIRYRCRGK-----EG 786
Query: 1325 SLLTCMEDGLWSFPEALCEL----MCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPG 1380
+ T +G W PE C + +C PP +PN+ T ++ G C+
Sbjct: 787 WIHTVCINGRWD-PEVNCSMAQIQLCPPPPQIPNSHNMTTTL---NYRDGEKVSVLCQEN 842
Query: 1381 YHVPGSSRKSKKRAFKTQCTQDGSWQE-GACV-PVTCDPPPPKFHGL------------- 1425
Y + + K DG WQ CV + C PP HG
Sbjct: 843 YLIQEGEEITCK---------DGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAH 893
Query: 1426 -----YQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSV 1480
Y C GF+ + E C G W+ S C+ + C
Sbjct: 894 GTKLSYTCEGGFRISEENETTC-----------------YMGKWS-SPPQCEGL--PCKS 933
Query: 1481 PNELNSNLKLQCPDGYAIGSECATSCLD 1508
P E++ + D Y G E C +
Sbjct: 934 PPEISHGVVAHMSDSYQYGEEVTYKCFE 961
Score = 43.1 bits (100), Expect = 0.002
Identities = 67/323 (20%), Positives = 102/323 (31%), Gaps = 56/323 (17%)
Query: 1209 ACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVT 1268
+CE+ C + N + G + T CR G+ R + T
Sbjct: 261 SCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGN------------TAK 308
Query: 1269 CTEGKWNKQVACEPVDCSIPD-------HHQVYAASFSCPEGTTFGSQCSFQCRHPAQLK 1321
CT W C C PD H + F G + C P+
Sbjct: 309 CTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSY 368
Query: 1322 GNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGY 1381
++ + C +DG WS P C C P + R K G C PGY
Sbjct: 369 WDH--IHCTQDG-WS-PAVPCLRKCYFPYLENGYNQNHGR----KFVQGKSIDVACHPGY 420
Query: 1382 HVPGSSRKSKKRAFKTQCTQDGSWQEGACVPV-TCDPPPPKFHGLYQCTNGFQF--NSEC 1438
+P K C ++G C+ V TC + + + + +
Sbjct: 421 ALP-------KAQTTVTCMENGWSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKA 473
Query: 1439 RIKCE-DSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPN-------------EL 1484
+ +C+ + G S I C KDG W+ C + C +P +L
Sbjct: 474 KYQCKLGYVTADGETSGSITCGKDG-WSAQ-PTCIK---SCDIPVFMNARTKNDFTWFKL 528
Query: 1485 NSNLKLQCPDGYAIGSECATSCL 1507
N L +C DGY + T +
Sbjct: 529 NDTLDYECHDGYESNTGSTTGSI 551
Score = 43.1 bits (100), Expect = 0.002
Identities = 68/322 (21%), Positives = 116/322 (36%), Gaps = 51/322 (15%)
Query: 1198 YSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELI 1257
+SP + C K+ + +EN ++ S + C+ GYV D E
Sbjct: 436 WSPTPRCIRVKTCSKSS---IDIENGFISESQYTYALKEKAKYQCKLGYVTA---DGET- 488
Query: 1258 KSQTGPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTF--GSQCSFQCR 1315
S ++TC + W+ Q C C IP V+ + + + T F ++C
Sbjct: 489 ------SGSITCGKDGWSAQPTCIK-SCDIP----VFMNARTKNDFTWFKLNDTLDYECH 537
Query: 1316 --HPAQLKGNNSLLTCMEDGLWSFP---EALCELMCLAPPPVPNADLQTARCRENKHKVG 1370
+ + + C +G P E CEL + VP+ +++++KVG
Sbjct: 538 DGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDR-------KKDQYKVG 590
Query: 1371 SFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPV------TCDPPPPKFHG 1424
K+ CKPG+ + G + QC G + +P+ +C PPP +G
Sbjct: 591 EVLKFSCKPGFTIVGPN--------SVQCYHFGLSPD---LPICKEQVQSCGPPPELLNG 639
Query: 1425 LYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNEL 1484
+ ++ ++ + G N I C DG W + VC + C EL
Sbjct: 640 NVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQC-VDGEWT-TLPVCIVEESTCGDIPEL 697
Query: 1485 NSNLKLQCPDGYAIGSECATSC 1506
Y G +C
Sbjct: 698 EHGWAQLSSPPYYYGDSVEFNC 719
Score = 41.2 bits (95), Expect = 0.008
Identities = 62/301 (20%), Positives = 97/301 (32%), Gaps = 47/301 (15%)
Query: 1111 GDQKQETISVQLLDTKDQSHDLGL-HVLSCR-----NNPLIIPVVHDLSQPFYHSQAVRV 1164
G Q I+ + DT ++D+ + V+ C N I+ + + ++ QAVR
Sbjct: 117 GYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVR- 175
Query: 1165 SFSSPLVAISGVALRSFDNFDPVTLSSCQRGETYSPAEQSCVHFACEKTDCPELAVENAS 1224
V SG + + C +S + CV +C+ D + +
Sbjct: 176 -----FVCNSGYKIEGDEEMH------CSDDGFWSKEKPKCVEISCKSPDVINGSPISQK 224
Query: 1225 LNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVACEPVD 1284
+ ++R+ C GY R D CTE W +CE
Sbjct: 225 IIYKENERFQ-----YKCNMGYEYSERGD-------------AVCTESGWRPLPSCEEKS 266
Query: 1285 CSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCEL 1344
C P + T G + ++QCR+ + C G W P C L
Sbjct: 267 CDNPYIPNGDYSPLRIKHRT--GDEITYQCRNGFYPATRGNTAKCTSTG-W-IPAPRCTL 322
Query: 1345 MCLAPPPVPNADLQTARCRENKH--KVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQD 1402
P + + L R VG + Y C + P S CTQD
Sbjct: 323 KPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWD-----HIHCTQD 377
Query: 1403 G 1403
G
Sbjct: 378 G 378
Score = 35.4 bits (80), Expect = 0.45
Identities = 31/132 (23%), Positives = 45/132 (34%), Gaps = 15/132 (11%)
Query: 1346 CLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW 1405
C PP N ++ T + + G+ YKC+PGY G+ + G W
Sbjct: 21 CNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGN---------VIMVCRKGEW 71
Query: 1406 QE----GACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGS-NVIHCRK 1460
C C P G + T G F + ++ Q LG N C
Sbjct: 72 VALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDT 131
Query: 1461 DGTWNGSFHVCQ 1472
DG W +C+
Sbjct: 132 DG-WTNDIPICE 142
>gi|110611237 coagulation factor XIII B subunit precursor [Homo
sapiens]
Length = 661
Score = 58.5 bits (140), Expect = 5e-08
Identities = 73/288 (25%), Positives = 107/288 (37%), Gaps = 46/288 (15%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPELA-VENASLNCSSSDRYHGAQCTVSCRTGYVLQI 1250
C+ G+ P + C+ EK C E +EN + N S Y+G + T +C++GY+L
Sbjct: 316 CEDGKWTEPPK--CIE-GQEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLH- 371
Query: 1251 RRDDELIKSQTGPSVTVTCTEGKWNKQVAC--EPVDCSIPDHHQVYAASFSCPEGTTFGS 1308
S +TC GKW C +C P A + GS
Sbjct: 372 ------------GSNEITCNRGKWTLPPECVENNENCKHPPVVMNGAVADGILASYATGS 419
Query: 1309 QCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHK 1368
++C L+G S ++ E G WS P +CL P V N D E K K
Sbjct: 420 SVEYRCNEYYLLRG--SKISRCEQGKWSSPP-----VCLEPCTV-NVDYMNRNNIEMKWK 471
Query: 1369 V------GSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACV----PVTCDPP 1418
G + CK GY + + S+ QC + G + C C P
Sbjct: 472 YEGKVLHGDLIDFVCKQGYDLSPLTPLSE---LSVQCNR-GEVKYPLCTRKESKGMCTSP 527
Query: 1419 PPKFHG--LYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTW 1464
P HG + + ++ S +C D + GS +C DG W
Sbjct: 528 PLIKHGVIISSTVDTYENGSSVEYRCFDHHFLE--GSREAYC-LDGMW 572
Score = 42.4 bits (98), Expect = 0.004
Identities = 63/311 (20%), Positives = 105/311 (33%), Gaps = 57/311 (18%)
Query: 1222 NASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVAC- 1280
N+ + S+ HG + C + + S + C +GKW + C
Sbjct: 282 NSKIQTHSTTYRHGEIVHIECELNFEIH-------------GSAEIRCEDGKWTEPPKCI 328
Query: 1281 ---EPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSF 1337
E V C P + AA+ G + ++ C+ L G+N +TC G W+
Sbjct: 329 EGQEKVACEEPPFIENGAANLHSKIYYN-GDKVTYACKSGYLLHGSNE-ITC-NRGKWTL 385
Query: 1338 PEALCE--LMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGS-------SR 1388
P E C PP V N + + GS +Y+C Y + GS +
Sbjct: 386 PPECVENNENCKHPPVVMNGAVADGILA--SYATGSSVEYRCNEYYLLRGSKISRCEQGK 443
Query: 1389 KSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHG---LYQCTNGFQFN-----SECRI 1440
S CT + + + + HG + C G+ + SE +
Sbjct: 444 WSSPPVCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSV 503
Query: 1441 KCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCP-DGYAIG 1499
+C + L C + +E +G C+ P + + + D Y G
Sbjct: 504 QCNRGEVKYPL------CTR-----------KESKGMCTSPPLIKHGVIISSTVDTYENG 546
Query: 1500 SECATSCLDHN 1510
S C DH+
Sbjct: 547 SSVEYRCFDHH 557
Score = 35.4 bits (80), Expect = 0.45
Identities = 46/229 (20%), Positives = 78/229 (34%), Gaps = 54/229 (23%)
Query: 1242 CRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVAC--EPVDCSIPDHHQVYAASFS 1299
C +GY +D+E+++ C W+ Q C E C P+ +Y ++S
Sbjct: 118 CASGYKTTGGKDEEVVQ----------CLSDGWSSQPTCRKEHETCLAPE---LYNGNYS 164
Query: 1300 CPEGT-TFGSQCSFQCRHPAQLKGNNSL--LTCMEDGLWSFPEALCELMCLAPPPVPNAD 1356
+ T + ++C G + C+ G WS +L C + + N
Sbjct: 165 TTQKTFKVKDKVQYECATGYYTAGGKKTEEVECLTYG-WSLTPKCTKLKCSSLRLIENGY 223
Query: 1357 LQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVT-- 1414
+ ++ G ++ C Y++ GS QC G + E PV
Sbjct: 224 FHPVK---QTYEEGDVVQFFCHENYYLSGSDL--------IQCYNFGWYPES---PVCEG 269
Query: 1415 ----CDPPPPKFHGLYQ---------------CTNGFQFNSECRIKCED 1444
C PPP + Q C F+ + I+CED
Sbjct: 270 RRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCED 318
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 57.8 bits (138), Expect = 9e-08
Identities = 86/358 (24%), Positives = 131/358 (36%), Gaps = 63/358 (17%)
Query: 1210 CEKTDC---PELAVENASLNCSSSDRYH-GAQCTVSCRTGYVLQIRRDDELIKSQTGPSV 1265
C++ C P +A N S + +H G+ T C G R ++ + PS+
Sbjct: 153 CDRIICGLPPTIA--NGDFTSISREYFHYGSVVTYHCNLG-----SRGKKVFELVGEPSI 205
Query: 1266 TVTCTE---GKWNKQV--ACEPVDCSIPDHHQVYAAS-----FSCPEGTTFGSQCSFQCR 1315
T + G W+ P C+ P+ S FS E F Q F +
Sbjct: 206 YCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMK 265
Query: 1316 HPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKY 1375
P+ +K C W C +C PP V +A+ +T R ++N G Y
Sbjct: 266 GPSHVK-------CQALNKWEPELPSCSRVCQPPPDVLHAE-RTQRDKDN-FSPGQEVFY 316
Query: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDP---PPPKFHGLYQCTN 1430
C+PGY + GS+ CT G W A C +CD P H L+
Sbjct: 317 SCEPGYDLRGST--------YLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPL-- 366
Query: 1431 GFQFNSECRIKCEDSDASQGLGSNVIHC---RKDGTWNGSFHVCQEMQGQCSVPNELNSN 1487
Q ++ C+ + Q GS+ +C + WN S VC+ + C P +
Sbjct: 367 NLQLGAKVDFVCD--EGFQLKGSSASYCVLAGMESLWNSSVPVCE--RKSCETPPVPVNG 422
Query: 1488 LKLQCPD---GYAIGSECATS--CLDHNSESIILPMNVTVRDIPHW-LNPTRVERVVC 1539
+ D G I C T + H+S IL N HW + P +++ C
Sbjct: 423 MVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTA-----HWSMKPPICQQIFC 475
Score = 41.2 bits (95), Expect = 0.008
Identities = 28/118 (23%), Positives = 47/118 (39%), Gaps = 18/118 (15%)
Query: 1369 VGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGLY 1426
+G++ Y+C+PGY R F C ++ W + C +C PP +G+
Sbjct: 57 IGTYLNYECRPGY---------SGRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMA 107
Query: 1427 QCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGT---WNGSFHVCQEMQGQCSVP 1481
QF S+ + C + +GS+ C G W+ VC + C +P
Sbjct: 108 HVIKDIQFRSQIKYSC--PKGYRLIGSSSATCIISGNTVIWDNKTPVCDRI--ICGLP 161
Score = 39.7 bits (91), Expect = 0.024
Identities = 66/315 (20%), Positives = 110/315 (34%), Gaps = 75/315 (23%)
Query: 1307 GSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCE-LMCLAPPPVPNADLQTARCREN 1365
G+ +++CR G + C+++ +W+ + C+ C PP N + +
Sbjct: 58 GTYLNYECR--PGYSGRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQF 115
Query: 1366 KHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGS---W--QEGACVPVTCDPPPP 1420
+ ++ KY C GY + GSS C G+ W + C + C PP
Sbjct: 116 RSQI----KYSCPKGYRLIGSS--------SATCIISGNTVIWDNKTPVCDRIICGLPPT 163
Query: 1421 KFHGLYQCTNG--FQFNS----ECRIKCEDSDASQGLGSNVIHC-RKD---GTWNGSFHV 1470
+G + + F + S C + + +G I+C KD G W+G
Sbjct: 164 IANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQ 223
Query: 1471 CQEMQGQCSVPN--------------ELNSNLKLQCPDGYAIGSECATSCLDHNSESIIL 1516
C + +C+ PN LN ++ +C G+ + C N L
Sbjct: 224 C-IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPEL 282
Query: 1517 PMNVTV-RDIPHWLNPTRVER--------------------------VVCTAGLKWYPHP 1549
P V + P L+ R +R + CT W P
Sbjct: 283 PSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDW--SP 340
Query: 1550 ALIHC-VKGCEPFMG 1563
A C VK C+ F+G
Sbjct: 341 AAPRCEVKSCDDFLG 355
>gi|5454086 sushi-repeat-containing protein, X-linked [Homo sapiens]
Length = 464
Score = 57.4 bits (137), Expect = 1e-07
Identities = 60/264 (22%), Positives = 98/264 (37%), Gaps = 49/264 (18%)
Query: 1235 GAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVY 1294
G +C + C+ GY L G S+ + + +W+ +V C+ C P
Sbjct: 82 GTRCDIRCQKGYELH------------GSSLLICQSNKRWSDKVICKQKRC--PTLAMPA 127
Query: 1295 AASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPN 1354
F C +G F S+C + C LKG + +TCM++ WS A C + + PP +
Sbjct: 128 NGGFKCVDGAYFNSRCEYYCSPGYTLKGERT-VTCMDNKAWSGRPASC--VDMEPPRIKC 184
Query: 1355 ADLQTARCRENKHKV--------------GSFCKYKCK---PGYHVPGSSRKSKKRAFKT 1397
++ NK V G K PG + P K + +
Sbjct: 185 PSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVY-- 242
Query: 1398 QCTQDGSWQEGAC---VPV---TCDPPPPKFHGLYQC-TNGFQFNSECRIKCEDSDASQG 1450
D + +G C V V C +G +C ++G + + C C QG
Sbjct: 243 ----DRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQG 298
Query: 1451 LGSNVIHCRKDGTWNGSFHVCQEM 1474
+ V C+ + W+G+ C M
Sbjct: 299 SPARV--CQSNLAWSGTEPTCAAM 320
Score = 47.0 bits (110), Expect = 2e-04
Identities = 32/141 (22%), Positives = 55/141 (39%), Gaps = 21/141 (14%)
Query: 1366 KHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA-CVPVTCDPPPPKFHG 1424
K +G+ C +C+ GY + GSS C + W + C C +G
Sbjct: 78 KTALGTRCDIRCQKGYELHGSSLLI--------CQSNKRWSDKVICKQKRCPTLAMPANG 129
Query: 1425 LYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQ--------- 1475
++C +G FNS C C + G + C + W+G C +M+
Sbjct: 130 GFKCVDGAYFNSRCEYYCSPGYTLK--GERTVTCMDNKAWSGRPASCVDMEPPRIKCPSV 187
Query: 1476 -GQCSVPNELNSNLKLQCPDG 1495
+ + PN+L + + P+G
Sbjct: 188 KERIAEPNKLTVRVSWETPEG 208
Score = 39.7 bits (91), Expect = 0.024
Identities = 35/143 (24%), Positives = 54/143 (37%), Gaps = 23/143 (16%)
Query: 1280 CEPVDCSIPDHHQVYAASFSCPEG----TTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLW 1335
C P+ D VY + P+G T G++C +C+ +L G +SLL C + W
Sbjct: 57 CSPIKVKYGD---VYCRA---PQGGYYKTALGTRCDIRCQKGYELHG-SSLLICQSNKRW 109
Query: 1336 SFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAF 1395
S + C N +C + + S C+Y C PGY + G
Sbjct: 110 SDKVICKQKRCPTLAMPANGGF---KCVDGAY-FNSRCEYYCSPGYTLKGER-------- 157
Query: 1396 KTQCTQDGSWQEGACVPVTCDPP 1418
C + +W V +PP
Sbjct: 158 TVTCMDNKAWSGRPASCVDMEPP 180
Score = 32.7 bits (73), Expect = 2.9
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 4/40 (10%)
Query: 1210 CEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQ 1249
C K + PE N + CSS +GA C SC GY LQ
Sbjct: 262 CGKLNAPE----NGYMKCSSDGDNYGATCEFSCIGGYELQ 297
>gi|118442839 complement factor H-related 1 [Homo sapiens]
Length = 330
Score = 56.2 bits (134), Expect = 2e-07
Identities = 54/206 (26%), Positives = 83/206 (40%), Gaps = 40/206 (19%)
Query: 1267 VTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTF--GSQCSFQCRHPAQLKGNN 1324
+TCTE W+ C + C P ++ S G T G C +L+ N
Sbjct: 70 ITCTEEGWSPTPKCLRL-CFFPFVENGHSES----SGQTHLEGDTVQIICNTGYRLQNNE 124
Query: 1325 SLLTCMEDGLWSFPEAL--CELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYH 1382
+ ++C+E G WS P + C+ PP V NA + + + +K+ G +Y+C+ Y
Sbjct: 125 NNISCVERG-WSTPPKCRSTDTSCVNPPTVQNAHILSRQM--SKYPSGERVRYECRSPYE 181
Query: 1383 VPGSSRKSKKRAFKTQCTQDGSWQEGA-CVPVT--CDPPPPKFHG--------------- 1424
+ G + C +G+W E C T C PPPP +G
Sbjct: 182 MFGDE--------EVMCL-NGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASS 232
Query: 1425 -LYQCTNGFQFNSECRIKCEDSDASQ 1449
YQC N +Q RI C + S+
Sbjct: 233 VEYQCQNLYQLEGNKRITCRNGQWSE 258
Score = 52.4 bits (124), Expect = 4e-06
Identities = 43/192 (22%), Positives = 78/192 (40%), Gaps = 29/192 (15%)
Query: 1220 VENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVA 1279
VEN S G + C TGY LQ ++ ++C E W+
Sbjct: 92 VENGHSESSGQTHLEGDTVQIICNTGYRLQNNENN------------ISCVERGWSTPPK 139
Query: 1280 CEPVDCSIPDHHQVYAASFSCPEGTTF--GSQCSFQCRHPAQLKGNNSLLTCMEDGLWSF 1337
C D S + V A + + + G + ++CR P ++ G+ ++ C+ +G W+
Sbjct: 140 CRSTDTSCVNPPTVQNAHILSRQMSKYPSGERVRYECRSPYEMFGDEEVM-CL-NGNWTE 197
Query: 1338 PEALCEL--MCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAF 1395
P + C PPP+ N D+ + + + S +Y+C+ Y + G+ R +
Sbjct: 198 PPQCKDSTGKCGPPPPIDNGDITSFPL--SVYAPASSVEYQCQNLYQLEGNKRIT----- 250
Query: 1396 KTQCTQDGSWQE 1407
++G W E
Sbjct: 251 ----CRNGQWSE 258
>gi|239758113 PREDICTED: similar to complement factor H-related 1
isoform 1 [Homo sapiens]
Length = 330
Score = 56.2 bits (134), Expect = 2e-07
Identities = 54/206 (26%), Positives = 83/206 (40%), Gaps = 40/206 (19%)
Query: 1267 VTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTF--GSQCSFQCRHPAQLKGNN 1324
+TCTE W+ C + C P ++ S G T G C +L+ N
Sbjct: 70 ITCTEEGWSPTPKCLRL-CFFPFVENGHSES----SGQTHLEGDTVQIICNTGYRLQNNE 124
Query: 1325 SLLTCMEDGLWSFPEAL--CELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYH 1382
+ ++C+E G WS P + C+ PP V NA + + + +K+ G +Y+C+ Y
Sbjct: 125 NNISCVERG-WSTPPKCRSTDTSCVNPPTVQNAHILSRQM--SKYPSGERVRYECRSPYE 181
Query: 1383 VPGSSRKSKKRAFKTQCTQDGSWQEGA-CVPVT--CDPPPPKFHG--------------- 1424
+ G + C +G+W E C T C PPPP +G
Sbjct: 182 MFGDE--------EVMCL-NGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASS 232
Query: 1425 -LYQCTNGFQFNSECRIKCEDSDASQ 1449
YQC N +Q RI C + S+
Sbjct: 233 VEYQCQNLYQLEGNKRITCRNGQWSE 258
Score = 52.4 bits (124), Expect = 4e-06
Identities = 43/192 (22%), Positives = 78/192 (40%), Gaps = 29/192 (15%)
Query: 1220 VENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVA 1279
VEN S G + C TGY LQ ++ ++C E W+
Sbjct: 92 VENGHSESSGQTHLEGDTVQIICNTGYRLQNNENN------------ISCVERGWSTPPK 139
Query: 1280 CEPVDCSIPDHHQVYAASFSCPEGTTF--GSQCSFQCRHPAQLKGNNSLLTCMEDGLWSF 1337
C D S + V A + + + G + ++CR P ++ G+ ++ C+ +G W+
Sbjct: 140 CRSTDTSCVNPPTVQNAHILSRQMSKYPSGERVRYECRSPYEMFGDEEVM-CL-NGNWTE 197
Query: 1338 PEALCEL--MCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAF 1395
P + C PPP+ N D+ + + + S +Y+C+ Y + G+ R +
Sbjct: 198 PPQCKDSTGKCGPPPPIDNGDITSFPL--SVYAPASSVEYQCQNLYQLEGNKRIT----- 250
Query: 1396 KTQCTQDGSWQE 1407
++G W E
Sbjct: 251 ----CRNGQWSE 258
>gi|62739188 complement factor H isoform b precursor [Homo sapiens]
Length = 449
Score = 55.1 bits (131), Expect = 6e-07
Identities = 78/331 (23%), Positives = 121/331 (36%), Gaps = 68/331 (20%)
Query: 1210 CEKTDC-PELAVENASLNCSSSD---RYHGAQCT-VSCRTGYVLQIRRDDELIKSQTGPS 1264
CE C P A EN + S+ + YH Q C +GY +I D+E+ S
Sbjct: 141 CEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGY--KIEGDEEMHCSD---- 194
Query: 1265 VTVTCTEGKWNKQVA-CEPVDCSIPD--HHQVYAASFSCPEGTTFGSQCSFQCRHPAQLK 1321
+G W+K+ C + C PD + + E F +C+ + +
Sbjct: 195 ------DGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSE--R 246
Query: 1322 GNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGY 1381
G+ C E G P CE P +PN D R KH+ G Y+C+ G+
Sbjct: 247 GD---AVCTESGWRPLPS--CEEKSCDNPYIPNGDYSPLRI---KHRTGDEITYQCRNGF 298
Query: 1382 HVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQ---------CTNGF 1432
+ +K CT G C CD P K GLY G
Sbjct: 299 YPATRGNTAK-------CTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGK 351
Query: 1433 QFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVP---NELNSN-- 1487
++ C E + G + IHC +DG W+ + + +C P N N N
Sbjct: 352 YYSYYCD---EHFETPSGSYWDHIHCTQDG-WSPAVPCLR----KCYFPYLENGYNQNHG 403
Query: 1488 --------LKLQCPDGYAI-GSECATSCLDH 1509
+ + C GYA+ ++ +C+++
Sbjct: 404 RKFVQGKSIDVACHPGYALPKAQTTVTCMEN 434
Score = 41.2 bits (95), Expect = 0.008
Identities = 62/301 (20%), Positives = 97/301 (32%), Gaps = 47/301 (15%)
Query: 1111 GDQKQETISVQLLDTKDQSHDLGL-HVLSCR-----NNPLIIPVVHDLSQPFYHSQAVRV 1164
G Q I+ + DT ++D+ + V+ C N I+ + + ++ QAVR
Sbjct: 117 GYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVR- 175
Query: 1165 SFSSPLVAISGVALRSFDNFDPVTLSSCQRGETYSPAEQSCVHFACEKTDCPELAVENAS 1224
V SG + + C +S + CV +C+ D + +
Sbjct: 176 -----FVCNSGYKIEGDEEMH------CSDDGFWSKEKPKCVEISCKSPDVINGSPISQK 224
Query: 1225 LNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVACEPVD 1284
+ ++R+ C GY R D CTE W +CE
Sbjct: 225 IIYKENERFQ-----YKCNMGYEYSERGD-------------AVCTESGWRPLPSCEEKS 266
Query: 1285 CSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCEL 1344
C P + T G + ++QCR+ + C G W P C L
Sbjct: 267 CDNPYIPNGDYSPLRIKHRT--GDEITYQCRNGFYPATRGNTAKCTSTG-W-IPAPRCTL 322
Query: 1345 MCLAPPPVPNADLQTARCRENKH--KVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQD 1402
P + + L R VG + Y C + P S CTQD
Sbjct: 323 KPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWD-----HIHCTQD 377
Query: 1403 G 1403
G
Sbjct: 378 G 378
Score = 35.4 bits (80), Expect = 0.45
Identities = 31/132 (23%), Positives = 45/132 (34%), Gaps = 15/132 (11%)
Query: 1346 CLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSW 1405
C PP N ++ T + + G+ YKC+PGY G+ + G W
Sbjct: 21 CNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGN---------VIMVCRKGEW 71
Query: 1406 QE----GACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGS-NVIHCRK 1460
C C P G + T G F + ++ Q LG N C
Sbjct: 72 VALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDT 131
Query: 1461 DGTWNGSFHVCQ 1472
DG W +C+
Sbjct: 132 DG-WTNDIPICE 142
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 54.7 bits (130), Expect = 7e-07
Identities = 90/381 (23%), Positives = 114/381 (29%), Gaps = 103/381 (27%)
Query: 1226 NCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVACEPV-- 1283
+CS + G +C C GY GP CT VAC+ V
Sbjct: 670 SCSCKAGFRGERCQAECELGYF--------------GPGCWQACT---CPVGVACDSVSG 712
Query: 1284 DCS--IPDHHQVYAASFSCPEGTTFGSQCSF--------------QCRHPAQLKGNNSLL 1327
+C P Q CP G TFG CS QCR P G +
Sbjct: 713 ECGKRCPAGFQGEDCGQECPVG-TFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA 771
Query: 1328 TCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSS 1387
C E G W C+ +C A D +T C VGS C+ C G++ P
Sbjct: 772 DCPE-GRWGLG---CQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQ 827
Query: 1388 RKSKKRAFKTQCTQDGSWQEGACVPVT----CDPPPPKFHGLYQCTNGFQFNSECRIKCE 1443
+ C DG C P T C P F C G + +C C
Sbjct: 828 T-------RCSCANDGH-----CHPATGHCSCAPGWTGFSCQRACDTG-HWGPDCSHPC- 873
Query: 1444 DSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQC-SVPNELNSNLKLQCPDGYAIGSEC 1502
+ S G GS C + G C + + QCP G+ G C
Sbjct: 874 --NCSAGHGS-----------------CDAISGLCLCEAGYVGPRCEQQCPQGH-FGPGC 913
Query: 1503 ATSC-------LDHNSESIILPMNVTVRDIPHWLNPTRVERVVCTAGLKWYPHPALIHCV 1555
C DH S + P H C AG + +C
Sbjct: 914 EQRCQCQHGAACDHVSGACTCPAGWRGTFCEH----------ACPAGFFGLDCRSACNCT 963
Query: 1556 KGCEPFMGDNYCDAINNRAFC 1576
G CDA+N C
Sbjct: 964 AGAA-------CDAVNGSCLC 977
Score = 50.1 bits (118), Expect = 2e-05
Identities = 111/460 (24%), Positives = 137/460 (29%), Gaps = 132/460 (28%)
Query: 1192 CQRGETYSPAEQSCVHFACEKTDCPE----LAVENASLNCSSSDRYHGAQCTVSCRTGYV 1247
CQ G T P C CPE LA E C D G + + C G +
Sbjct: 1048 CQNGGTCDPVSGHCA--------CPEGWAGLACEK---ECLPRDVRAGCRHSGGCLNGGL 1096
Query: 1248 LQIRRDDELIKSQ-TGPSVTVTCTEGKWNKQVACEPVDCSIPD----HHQVYAASFSCPE 1302
L + TG C G + + A CS P HH A CP
Sbjct: 1097 CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR---CSCPPGAACHHVTGACR--CPP 1151
Query: 1303 GTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARC 1362
G T GS C C P G + C MC P P T C
Sbjct: 1152 GFT-GSGCEQAC--PPGSFGED-----------------CAQMCQCPGENPACHPATGTC 1191
Query: 1363 RENKHKVGSFCKYKCKPGYHVPGSSR------------------------------KSKK 1392
G C+ +C PG + PG + +
Sbjct: 1192 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ 1251
Query: 1393 RAFKTQCTQ-DGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGL 1451
F CT G Q AC PVT G C G ++CE
Sbjct: 1252 GRFGPNCTHVCGCGQGAACDPVT---------GTCLCPPG-----RAGVRCERGCPQNRF 1297
Query: 1452 GSNVIH---CRKDGTWNGSFHVCQEMQGQCSVP-NELNSNLKLQCPDGYAIGSECATSCL 1507
G H CR G +C G CS + +L CP G G+ C C
Sbjct: 1298 GVGCEHTCSCRNGG-------LCHASNGSCSCGLGWTGRHCELACPPG-RYGAACHLECS 1349
Query: 1508 DHNSESIILPMNVTVRDIPHWLN-------PTRVERVVCTAGLKWYPH------------ 1548
HN+ S P T R P + P C GL W H
Sbjct: 1350 CHNN-STCEPATGTCRCGPGFYGQACEHPCPPGFHGAGC-QGLCWCQHGAPCDPISGRCL 1407
Query: 1549 -PALIH---CVKGCEPFMGDNYCDAINNRAFCNYDGGDCC 1584
PA H C +GCEP ++ + + R C+ DGG C
Sbjct: 1408 CPAGFHGHFCERGCEP---GSFGEGCHQR--CDCDGGAPC 1442
Score = 47.0 bits (110), Expect = 2e-04
Identities = 86/401 (21%), Positives = 132/401 (32%), Gaps = 86/401 (21%)
Query: 1180 SFDNFDPVTLSSCQRGETYSPAEQSC------VHFACEKTDCPELAVENASLNCSSSDRY 1233
SF + +T C+ G T C C +T P+ +N S +CS +
Sbjct: 515 SFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGG 574
Query: 1234 HGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVACEPVDCSIPDHHQV 1293
T +CR +G + C +G + K + + H++
Sbjct: 575 TCDSVTGACRCP------------PGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL 622
Query: 1294 YAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVP 1353
Y A C G +G C C W+F E P
Sbjct: 623 YGACL-CDPG-LYGRFCHLTCPP------------------WAFGPGCSEECQCVQPHTQ 662
Query: 1354 NADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGAC-VP 1412
+ D + C G C+ +C+ GY P G WQ C V
Sbjct: 663 SCDKRDGSCSCKAGFRGERCQAECELGYFGP------------------GCWQACTCPVG 704
Query: 1413 VTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
V CD + +C GFQ +C +C +G+ ++C + G+ C
Sbjct: 705 VACDSVSGECG--KRCPAGFQ-GEDCGQECP-------VGTFGVNCSSSCSCGGA--PCH 752
Query: 1473 EMQGQCSV-PNELNSNLKLQCPDG-YAIGSE--C-----ATSCLDHNSESIILPMNVTVR 1523
+ GQC P + + CP+G + +G + C A C + LP V R
Sbjct: 753 GVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSR 812
Query: 1524 --DI--PHWLNPTRVERVVCTAGLKWYPHPALIHCVKGCEP 1560
D+ W P+ R C+ + HPA HC C P
Sbjct: 813 CQDVCPAGWYGPSCQTR--CSCANDGHCHPATGHC--SCAP 849
Score = 45.4 bits (106), Expect = 4e-04
Identities = 87/368 (23%), Positives = 111/368 (30%), Gaps = 92/368 (25%)
Query: 1192 CQRGETYSPAEQSCV-----HFACEKTDCP--ELAVENASLNCSSSDRYHGAQCTVSCRT 1244
C G T S EQ+C + CP A A+ CS + YHG C C
Sbjct: 1149 CPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPP 1208
Query: 1245 G-YVLQIRRDDELIKSQT---------------GPSVTVTCTEGKWNKQ----------V 1278
G Y + + + G +TC +G++
Sbjct: 1209 GRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGA 1268
Query: 1279 ACEPVD--CSIPDHHQVYAASFSCPEGTTFGSQCSF--QCRHPAQLKGNNSLLTCMEDGL 1334
AC+PV C P CP+ FG C CR+ +N +C GL
Sbjct: 1269 ACDPVTGTCLCPPGRAGVRCERGCPQNR-FGVGCEHTCSCRNGGLCHASNGSCSC---GL 1324
Query: 1335 WSFPEALCELMCLAPPPVPNA--------------DLQTARCRENKHKVGSFCKYKCKPG 1380
+ CEL C PP A + T CR G C++ C PG
Sbjct: 1325 -GWTGRHCELAC--PPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPG 1381
Query: 1381 YHVPGSSRKSKKRAFKTQCTQDGSW-QEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECR 1439
+H G Q W Q GA CDP G C GF C
Sbjct: 1382 FHGAG--------------CQGLCWCQHGA----PCDP----ISGRCLCPAGFH-GHFCE 1418
Query: 1440 IKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQC-SVPNELNSNLKLQCPDGYAI 1498
CE +G C DG C + G C P + L C G
Sbjct: 1419 RGCEPGSFGEGCHQ---RCDCDGG-----APCDPVTGLCLCPPGRSGATCNLDCRRG-QF 1469
Query: 1499 GSECATSC 1506
G C C
Sbjct: 1470 GPSCTLHC 1477
Score = 37.7 bits (86), Expect = 0.091
Identities = 67/295 (22%), Positives = 98/295 (33%), Gaps = 68/295 (23%)
Query: 1223 ASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVACEP 1282
A+ +CS + + G C +C TG+ GP + C + +C+
Sbjct: 841 ATGHCSCAPGWTGFSCQRACDTGH--------------WGPDCSHPCNCSAGHG--SCDA 884
Query: 1283 VD--CSIPDHHQVYAASFSCPEGTTFGSQCS--FQCRHPAQLKGNNSLLTCMEDGLWSFP 1338
+ C + CP+G FG C QC+H A + TC +F
Sbjct: 885 ISGLCLCEAGYVGPRCEQQCPQG-HFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFC 943
Query: 1339 EALCELMCLAPPPVPNADLQTA-RCRENK--HKVGSFCKYKCKPGYHVPGSSRKSKKRAF 1395
E C P D ++A C V C C G P + +
Sbjct: 944 EHAC------PAGFFGLDCRSACNCTAGAACDAVNGSC--LCPAGRRGPRCAETCPAHTY 995
Query: 1396 KTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNV 1455
C+Q + GA +CDP HG C G+ S C + + G N
Sbjct: 996 GHNCSQACACFNGA----SCDP----VHGQCHCAPGWMGPS-----CLQACPAGLYGDNC 1042
Query: 1456 IH---CRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSECATSCL 1507
H C+ GT C + G C+ CP+G+A G C CL
Sbjct: 1043 RHSCLCQNGGT-------CDPVSGHCA------------CPEGWA-GLACEKECL 1077
>gi|5031695 H factor (complement)-like 3 [Homo sapiens]
Length = 270
Score = 52.0 bits (123), Expect = 5e-06
Identities = 49/208 (23%), Positives = 80/208 (38%), Gaps = 42/208 (20%)
Query: 1220 VENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVA 1279
VEN S G + C TGY LQ ++ ++C E W+
Sbjct: 92 VENGHSESSGQTHLEGDTVQIICNTGYRLQNNENN------------ISCVERGWSTPPK 139
Query: 1280 CEPV----DCSIP---DHHQV--YAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCM 1330
C C P D+ + + S P GS +QC++ QL+GNN +TC
Sbjct: 140 CRSTISAEKCGPPPPIDNGDITSFLLSVYAP-----GSSVEYQCQNLYQLEGNNQ-ITC- 192
Query: 1331 EDGLWSFPEALCELMCLAPPPVPNADLQTARCRENK--HKVGSFCKYKCKPGYHVPGSSR 1388
+G WS P + ++ + +++ + K + G ++ CK GYH
Sbjct: 193 RNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYH------ 246
Query: 1389 KSKKRAFKTQCTQDGSWQEGACVPVTCD 1416
+K +F+ C Q G V +C+
Sbjct: 247 PTKSHSFRAMC------QNGKLVYPSCE 268
Score = 35.4 bits (80), Expect = 0.45
Identities = 41/169 (24%), Positives = 63/169 (37%), Gaps = 35/169 (20%)
Query: 1301 PEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTA 1360
P G F C + P+ K + +TC E+G WS P C +C P V N +++
Sbjct: 46 PTGEVFYYSCEYNFVSPS--KSFWTRITCAEEG-WS-PTPKCLRLCFFPF-VENGHSESS 100
Query: 1361 RCRENKHKVGSFCKYKCKPGYHVPGSSRKSK--KRAFKT--QCTQDGSWQEGACVPVTCD 1416
H G + C GY + + +R + T +C S ++ C
Sbjct: 101 G---QTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKCRSTISAEK-------CG 150
Query: 1417 PPPPKFHG----------------LYQCTNGFQFNSECRIKCEDSDASQ 1449
PPPP +G YQC N +Q +I C + S+
Sbjct: 151 PPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSE 199
>gi|4506875 selectin L precursor [Homo sapiens]
Length = 372
Score = 51.6 bits (122), Expect = 6e-06
Identities = 41/170 (24%), Positives = 68/170 (40%), Gaps = 26/170 (15%)
Query: 1328 TCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSF-----CKYKCKPGYH 1382
TC D + P+ + C P+ +L T C H +G+F C + C G +
Sbjct: 179 TCNCDVGYYGPQCQFVIQC---EPLEAPELGTMDCT---HPLGNFSFSSQCAFSCSEGTN 232
Query: 1383 VPGSSRKSKKRAFKTQCTQDGSWQ--EGACVPVTCDPPPPKFHGLYQCTN---GFQFNSE 1437
+ G +T C G+W E C + C+P G+ C++ F F S
Sbjct: 233 LTGIE--------ETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSA 284
Query: 1438 CRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSN 1487
C C S+ ++ +G C G W+ +CQ++ S+ E + N
Sbjct: 285 CTFIC--SEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYN 332
Score = 49.7 bits (117), Expect = 2e-05
Identities = 54/209 (25%), Positives = 77/209 (36%), Gaps = 39/209 (18%)
Query: 1212 KTDCPELAVEN----ASLNCSSSDRYHGAQC-TVSCRTGYVLQIRRDDELIKSQTGPSVT 1266
K DC E+ ++ N + + A C T SC+ E+I + T
Sbjct: 125 KEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYT----- 179
Query: 1267 VTCTEGKWNKQ----VACEPVDCSIPDHHQVYAASFSCPEGT-TFGSQCSFQCRHPAQLK 1321
C G + Q + CEP++ ++ + P G +F SQC+F C L
Sbjct: 180 CNCDVGYYGPQCQFVIQCEPLEAP-----ELGTMDCTHPLGNFSFSSQCAFSCSEGTNLT 234
Query: 1322 GNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSF-----CKYK 1376
G TC G WS PE C+++ P P DL C H + SF C +
Sbjct: 235 GIEET-TCGPFGNWSSPEPTCQVIQCEPLSAP--DLGIMNC---SHPLASFSFTSACTFI 288
Query: 1377 CKPGYHVPGSSRKSKKRAFKTQCTQDGSW 1405
C G + G KT C G W
Sbjct: 289 CSEGTELIGKK--------KTICESSGIW 309
>gi|14550407 complement component 2 isoform 1 preproprotein [Homo
sapiens]
Length = 752
Score = 50.1 bits (118), Expect = 2e-05
Identities = 48/206 (23%), Positives = 82/206 (39%), Gaps = 40/206 (19%)
Query: 1286 SIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFP------- 1338
S P + + +F+ G GS ++ C P L + + C G W P
Sbjct: 23 SCPQNVNISGGTFTLSHGWAPGSLLTYSC--PQGLYPSPASRLCKSSGQWQTPGATRSLS 80
Query: 1339 EALCE-LMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKT 1397
+A+C+ + C AP N + T R + VG ++C+ G+ + GS +
Sbjct: 81 KAVCKPVRCPAPVSFENG-IYTPRL--GSYPVGGNVSFECEDGFILRGSPVR-------- 129
Query: 1398 QCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTN----------GFQFNSECRIKCEDSDA 1447
QC +G W V CD +G C N GF+F +++ S
Sbjct: 130 QCRPNGMWDGETAV---CD------NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSN 180
Query: 1448 SQGLGSNVIHCRKDGTWNGSFHVCQE 1473
GS+ C+ +G W+G+ +C++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 50.1 bits (118), Expect = 2e-05
Identities = 35/122 (28%), Positives = 45/122 (36%), Gaps = 21/122 (17%)
Query: 1370 GSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQ---------EGACVPVTCDPPPP 1420
GS Y C G + +SR C G WQ + C PV C P
Sbjct: 44 GSLLTYSCPQGLYPSPASRL---------CKSSGQWQTPGATRSLSKAVCKPVRCPAPVS 94
Query: 1421 KFHGLYQCTNG-FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCS 1479
+G+Y G + +CED +G S V CR +G W+G VC G C
Sbjct: 95 FENGIYTPRLGSYPVGGNVSFECEDGFILRG--SPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 1480 VP 1481
P
Sbjct: 153 NP 154
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,923,301
Number of Sequences: 37866
Number of extensions: 4078513
Number of successful extensions: 21995
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 369
Number of HSP's that attempted gapping in prelim test: 18972
Number of HSP's gapped (non-prelim): 2360
length of query: 1627
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1511
effective length of database: 13,855,062
effective search space: 20934998682
effective search space used: 20934998682
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.