Guide to the Human Genome
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Search of human proteins with 37574614

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|37574614 nucleoside diphosphate kinase 7 isoform b [Homo
sapiens]
         (340 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|37574614 nucleoside diphosphate kinase 7 isoform b [Homo sapi...   688   0.0  
gi|7019465 nucleoside diphosphate kinase 7 isoform a [Homo sapiens]   688   0.0  
gi|148839372 thioredoxin domain containing 3 [Homo sapiens]           144   1e-34
gi|4505413 non-metastatic cells 5, protein expressed in (nucleos...   122   6e-28
gi|5031951 nucleoside diphosphate kinase type 6 [Homo sapiens]         93   4e-19
gi|66392203 NME1-NME2 protein [Homo sapiens]                           89   7e-18
gi|30023828 thioredoxin domain containing 6 [Homo sapiens]             81   1e-15
gi|4826862 nucleoside diphosphate kinase 4 [Homo sapiens]              75   6e-14
gi|37693993 nucleoside diphosphate kinase 3 [Homo sapiens]             74   2e-13
gi|38045913 non-metastatic cells 1, protein (NM23A) expressed in...    71   1e-12
gi|4557797 non-metastatic cells 1, protein (NM23A) expressed in ...    71   1e-12
gi|66392227 nucleoside diphosphate kinase B [Homo sapiens]             70   2e-12
gi|66392205 nucleoside diphosphate kinase B [Homo sapiens]             70   2e-12
gi|66392192 nucleoside diphosphate kinase B [Homo sapiens]             70   2e-12
gi|4505409 nucleoside diphosphate kinase B [Homo sapiens]              70   2e-12
gi|47078261 double C2-like domains, alpha [Homo sapiens]               31   1.4  
gi|112363080 microtubule associated serine/threonine kinase 2 [H...    30   3.1  
gi|191251777 breast carcinoma amplified sequence 1 [Homo sapiens]      29   5.3  
gi|11321597 kinase insert domain receptor precursor [Homo sapiens]     28   9.0  
gi|21450729 hypothetical protein LOC219833 [Homo sapiens]              28   9.0  

>gi|37574614 nucleoside diphosphate kinase 7 isoform b [Homo
           sapiens]
          Length = 340

 Score =  688 bits (1776), Expect = 0.0
 Identities = 340/340 (100%), Positives = 340/340 (100%)

Query: 1   MHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLA 60
           MHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLA
Sbjct: 1   MHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLA 60

Query: 61  LIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTG 120
           LIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTG
Sbjct: 61  LIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTG 120

Query: 121 PIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAR 180
           PIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAR
Sbjct: 121 PIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAR 180

Query: 181 EMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNM 240
           EMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNM
Sbjct: 181 EMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNM 240

Query: 241 DRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHL 300
           DRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHL
Sbjct: 241 DRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHL 300

Query: 301 RPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN 340
           RPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN
Sbjct: 301 RPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN 340


>gi|7019465 nucleoside diphosphate kinase 7 isoform a [Homo sapiens]
          Length = 376

 Score =  688 bits (1776), Expect = 0.0
 Identities = 340/340 (100%), Positives = 340/340 (100%)

Query: 1   MHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLA 60
           MHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLA
Sbjct: 37  MHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLA 96

Query: 61  LIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTG 120
           LIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTG
Sbjct: 97  LIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTG 156

Query: 121 PIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAR 180
           PIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAR
Sbjct: 157 PIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAR 216

Query: 181 EMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNM 240
           EMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNM
Sbjct: 217 EMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNM 276

Query: 241 DRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHL 300
           DRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHL
Sbjct: 277 DRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHL 336

Query: 301 RPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN 340
           RPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN
Sbjct: 337 RPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN 376


>gi|148839372 thioredoxin domain containing 3 [Homo sapiens]
          Length = 588

 Score =  144 bits (362), Expect = 1e-34
 Identities = 88/266 (33%), Positives = 147/266 (55%), Gaps = 17/266 (6%)

Query: 56  EKTLALIKPDAI-SKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELI 114
           EKTLAL++P+    +  +++ II    F I + + ++LS KEA     ++++  +FN+LI
Sbjct: 316 EKTLALLRPNLFHERKDDVLRIIKDEDFKILEQRQVVLSEKEAQALCKEYENEDYFNKLI 375

Query: 115 QFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIR-NAAHGPD 173
           + +T+GP +A+ +LRD+ +  WK+LLGP     A     ES+ A F  D +  N  +G D
Sbjct: 376 ENMTSGPSLALVLLRDNGLQYWKQLLGPRTVEEAIEYFPESLCAQFAMDSLPVNQLYGSD 435

Query: 174 SFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEIS 233
           S  +A RE++ FFP     G             ++KPHA SE    +IL  +++AGF+++
Sbjct: 436 SLETAEREIQHFFPLQSTLG-------------LIKPHATSE-QREQILKIVKEAGFDLT 481

Query: 234 AMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPAD 293
            ++   +    +E+ Y    G    Y D++  +  GP + M + + NA   +R   GP D
Sbjct: 482 QVKKMFLTPEQIEKIYPKVTG-KDFYKDLLEMLSVGPSMVMILTKWNAVAEWRRLMGPTD 540

Query: 294 PEIARHLRPGTLRAIFGKTKIQNAVH 319
           PE A+ L P ++RA FG +K++N VH
Sbjct: 541 PEEAKLLSPDSIRAQFGISKLKNIVH 566



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 42/132 (31%), Positives = 77/132 (58%), Gaps = 1/132 (0%)

Query: 56  EKTLALIKPDAISKAGE-IIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELI 114
           + TL LIKP A S+  E I++I+ +AGF +T++K M L+ ++    +     + F+ +L+
Sbjct: 451 QSTLGLIKPHATSEQREQILKIVKEAGFDLTQVKKMFLTPEQIEKIYPKVTGKDFYKDLL 510

Query: 115 QFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDS 174
           + ++ GP + M + + +A+ EW+RL+GP +   A+  + +SIRA FG   ++N  HG  +
Sbjct: 511 EMLSVGPSMVMILTKWNAVAEWRRLMGPTDPEEAKLLSPDSIRAQFGISKLKNIVHGASN 570

Query: 175 FASAAREMELFF 186
              A   +   F
Sbjct: 571 AYEAKEVVNRLF 582



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 63/307 (20%), Positives = 125/307 (40%), Gaps = 39/307 (12%)

Query: 58  TLALIKPDAI--SKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQ 115
           ++A+IKPDA+   K  EI   I KAGF I      +L+ ++ ++F+     +  F E + 
Sbjct: 156 SIAIIKPDAVISKKVLEIKRKITKAGFIIEAEHKTVLTEEQVVNFYSRIADQCDFEEFVS 215

Query: 116 FITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDA----------------------- 152
           F+T+G    +       + +  +   P+     +TD                        
Sbjct: 216 FMTSGLSYIL------VVSQGSKHNPPSEETEPQTDTEPNERSEDQPEVEAQVTPGMMKN 269

Query: 153 -SESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPH 211
             +S++       +       +  A+ A+ M+ FFP           K    T  +++P+
Sbjct: 270 KQDSLQEYLERQHLAQLCDIEEDAANVAKFMDAFFPDFKKMKSMKLEK----TLALLRPN 325

Query: 212 AVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPC 271
              E     +L  I+D  F+I   +   +     +   + Y+     ++ ++  M SGP 
Sbjct: 326 LFHE-RKDDVLRIIKDEDFKILEQRQVVLSEKEAQALCKEYEN-EDYFNKLIENMTSGPS 383

Query: 272 VAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQ-NAVHCTDLPEDGLLE 330
           +A+ + ++N  + +++  GP   E A    P +L A F    +  N ++ +D  E    E
Sbjct: 384 LALVLLRDNGLQYWKQLLGPRTVEEAIEYFPESLCAQFAMDSLPVNQLYGSDSLETAERE 443

Query: 331 VQYFFKI 337
           +Q+FF +
Sbjct: 444 IQHFFPL 450


>gi|4505413 non-metastatic cells 5, protein expressed in
           (nucleoside-diphosphate kinase) [Homo sapiens]
          Length = 212

 Score =  122 bits (305), Expect = 6e-28
 Identities = 59/132 (44%), Positives = 89/132 (67%)

Query: 56  EKTLALIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQ 115
           EKTLA+IKPD + K  EI +II ++GFTI + + + LS ++  +F+V+   + FF  L  
Sbjct: 13  EKTLAIIKPDIVDKEEEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTA 72

Query: 116 FITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSF 175
           ++++GP++AM + R  AI  W  LLGP NS VA+    +S+RA++GTD +RNA HG + F
Sbjct: 73  YMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTDDLRNALHGSNDF 132

Query: 176 ASAAREMELFFP 187
           A+A RE+   FP
Sbjct: 133 AAAEREIRFMFP 144



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 36/132 (27%), Positives = 63/132 (47%), Gaps = 3/132 (2%)

Query: 204 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 263
           T  I+KP  V +    +I   I  +GF I   +   +       FY    G +  + ++ 
Sbjct: 15  TLAIIKPDIVDKE--EEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVEKYGKMF-FPNLT 71

Query: 264 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 323
             M SGP VAM + ++ A   + E  GP +  +A+   P +LRAI+G   ++NA+H ++ 
Sbjct: 72  AYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTDDLRNALHGSND 131

Query: 324 PEDGLLEVQYFF 335
                 E+++ F
Sbjct: 132 FAAAEREIRFMF 143


>gi|5031951 nucleoside diphosphate kinase type 6 [Homo sapiens]
          Length = 194

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 51/134 (38%), Positives = 79/134 (58%), Gaps = 5/134 (3%)

Query: 58  TLALIKPDAISKAGEIIEIINKA----GFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 113
           TLALIKPDA++    I+E +++      F I +++ ++  +++   F+ +H+ R F+  L
Sbjct: 22  TLALIKPDAVAHP-LILEAVHQQILSNKFLIVRMRELLWRKEDCQRFYREHEGRFFYQRL 80

Query: 114 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 173
           ++F+ +GPI A  +   DAI  W+ L+GP     AR  A +SIR  FG    RN  HG D
Sbjct: 81  VEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSD 140

Query: 174 SFASAAREMELFFP 187
           S  SA+RE+  FFP
Sbjct: 141 SVVSASREIAAFFP 154



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 2/133 (1%)

Query: 204 TCCIVKPHAVSEGL-LGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDM 262
           T  ++KP AV+  L L  +   I    F I  M+     + + + FY  ++G    Y  +
Sbjct: 22  TLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQRFYREHEGRFF-YQRL 80

Query: 263 VTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTD 322
           V  M SGP  A  +   +A + +R   GP     ARH+ P ++R  FG T  +N  H +D
Sbjct: 81  VEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSD 140

Query: 323 LPEDGLLEVQYFF 335
                  E+  FF
Sbjct: 141 SVVSASREIAAFF 153


>gi|66392203 NME1-NME2 protein [Homo sapiens]
          Length = 267

 Score = 88.6 bits (218), Expect = 7e-18
 Identities = 74/283 (26%), Positives = 123/283 (43%), Gaps = 39/283 (13%)

Query: 56  EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 113
           E+T   IKPD + +   GEII+   + GF +  LK M  S     + +VD + RPFF  L
Sbjct: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGL 64

Query: 114 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 173
           ++++ +GP++AM     + +   + +LG  N   ++     +IR  F     R  A+   
Sbjct: 65  VKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRTMANLER 121

Query: 174 SFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEIS 233
           +F +                              +KP  V  GL+G+I+      GF + 
Sbjct: 122 TFIA------------------------------IKPDGVQRGLVGEIIKRFEQKGFRLV 151

Query: 234 AMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPAD 293
           AM+       ++++ Y   K     +  +V  M SGP VAM  +  N  KT R   G  +
Sbjct: 152 AMKFLRASEEHLKQHYIDLKD-RPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETN 210

Query: 294 PEIARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFK 336
           P  +   +PGT+R  F     +N +H +D  +    E+  +FK
Sbjct: 211 PADS---KPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFK 250



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 6/110 (5%)

Query: 202 NC--TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEY 259
           NC  T   +KP  V  GL+G+I+      GF +  ++        ++E Y   K     +
Sbjct: 3   NCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKD-RPFF 61

Query: 260 HDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIF 309
             +V  M+SGP VAM  +  N  KT R   G  +P  +   +PGT+R  F
Sbjct: 62  AGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDF 108


>gi|30023828 thioredoxin domain containing 6 [Homo sapiens]
          Length = 263

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 49/144 (34%), Positives = 76/144 (52%), Gaps = 6/144 (4%)

Query: 51  LGSRKEKTLALIKPDAIS--KAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRP 108
           + S +  TLA+IKPDA++  K  EII  I +AGF I   +   ++  E   F+       
Sbjct: 93  VSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEE 152

Query: 109 FFNELIQFITTGPIIAMEILR----DDAICEWKRLLGPANSGVARTDASESIRALFGTDG 164
            F +L+  + +GP   + + R    +D +  W+ ++GP +  VAR +  ES+RA +GT+ 
Sbjct: 153 AFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEM 212

Query: 165 IRNAAHGPDSFASAAREMELFFPS 188
             NA HG      A RE+ L FPS
Sbjct: 213 PFNAVHGSRDREDADRELALLFPS 236



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 48/140 (34%), Positives = 70/140 (50%), Gaps = 5/140 (3%)

Query: 203 CTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDM 262
           CT  I+KP AV+ G   +I+M I++AGFEI   +   M    V  FY+ +K     +  +
Sbjct: 99  CTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQ-HKAGEEAFEKL 157

Query: 263 VTEMYSGPCVAMEIQQ----NNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAV 318
           V  M SGP   + + +     +   T+R   GP DP +AR  +P +LRA +G     NAV
Sbjct: 158 VHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAV 217

Query: 319 HCTDLPEDGLLEVQYFFKIL 338
           H +   ED   E+   F  L
Sbjct: 218 HGSRDREDADRELALLFPSL 237


>gi|4826862 nucleoside diphosphate kinase 4 [Homo sapiens]
          Length = 187

 Score = 75.5 bits (184), Expect = 6e-14
 Identities = 41/141 (29%), Positives = 77/141 (54%), Gaps = 13/141 (9%)

Query: 55  KEKTLALIKPDAISK--AGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNE 112
           +E+TL  +KPD + +   G++I+   + GFT+  +KM+        + + D + +PF+  
Sbjct: 37  RERTLVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPA 96

Query: 113 LIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASE----SIRALFGTDGIRNA 168
           LI+++++GP++AM       + E   ++  + + +  TD++E    +IR  F     RN 
Sbjct: 97  LIRYMSSGPVVAM-------VWEGYNVVRASRAMIGHTDSAEAAPGTIRGDFSVHISRNV 149

Query: 169 AHGPDSFASAAREMELFFPSS 189
            H  DS   A RE++L+F SS
Sbjct: 150 IHASDSVEGAQREIQLWFQSS 170



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 42/147 (28%), Positives = 63/147 (42%), Gaps = 7/147 (4%)

Query: 190 GGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFY 249
           G  GP+ T + T      VKP  V   L+G ++      GF +  M+M       + E Y
Sbjct: 29  GSGGPSWTRERT---LVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHY 85

Query: 250 EVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIF 309
           +  +     Y  ++  M SGP VAM  +  N  +  R   G  D   A    PGT+R  F
Sbjct: 86  QDLRRKPF-YPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHTDSAEAA---PGTIRGDF 141

Query: 310 GKTKIQNAVHCTDLPEDGLLEVQYFFK 336
                +N +H +D  E    E+Q +F+
Sbjct: 142 SVHISRNVIHASDSVEGAQREIQLWFQ 168


>gi|37693993 nucleoside diphosphate kinase 3 [Homo sapiens]
          Length = 169

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 45/152 (29%), Positives = 79/152 (51%), Gaps = 6/152 (3%)

Query: 37  LVLIDYGDQYTARQLGSRKEKTLALIKPDAISK--AGEIIEIINKAGFTITKLKMMMLSR 94
           LVL  + + + A   G+  E+T   +KPD + +   GEI+    + GF +  LK++  S 
Sbjct: 4   LVLTIFANLFPAACTGAH-ERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASE 62

Query: 95  KEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASE 154
           +   + + + + RPF+  L++++ +GP++AM     D +   + L+G  N   A      
Sbjct: 63  ELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADA---PPG 119

Query: 155 SIRALFGTDGIRNAAHGPDSFASAAREMELFF 186
           +IR  F  +  +N  HG DS  SA RE+ L+F
Sbjct: 120 TIRGDFCIEVGKNLIHGSDSVESARREIALWF 151



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 4/133 (3%)

Query: 204 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 263
           T   VKP  V   L+G+I+      GF++ A+++       + E Y   +     Y  +V
Sbjct: 24  TFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYAELR-ERPFYGRLV 82

Query: 264 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 323
             M SGP VAM  Q  +  +T R   G  +P  A    PGT+R  F     +N +H +D 
Sbjct: 83  KYMASGPVVAMVWQGLDVVRTSRALIGATNPADA---PPGTIRGDFCIEVGKNLIHGSDS 139

Query: 324 PEDGLLEVQYFFK 336
            E    E+  +F+
Sbjct: 140 VESARREIALWFR 152


>gi|38045913 non-metastatic cells 1, protein (NM23A) expressed in
           isoform a [Homo sapiens]
          Length = 177

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 47/150 (31%), Positives = 75/150 (50%), Gaps = 11/150 (7%)

Query: 56  EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 113
           E+T   IKPD + +   GEII+   + GF +  LK M  S     + +VD + RPFF  L
Sbjct: 30  ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGL 89

Query: 114 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 173
           ++++ +GP++AM     + +   + +LG  N   ++     +IR  F     RN  HG D
Sbjct: 90  VKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 146

Query: 174 SFASAAREMELFFPSSGGCGPANTAKFTNC 203
           S  SA +E+ L+F       P     +T+C
Sbjct: 147 SVESAEKEIGLWF------HPEELVDYTSC 170



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 6/142 (4%)

Query: 196 NTAKFTNC--TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYK 253
           +T    NC  T   +KP  V  GL+G+I+      GF +  ++        ++E Y   K
Sbjct: 22  DTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLK 81

Query: 254 GVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTK 313
                +  +V  M+SGP VAM  +  N  KT R   G  +P  +   +PGT+R  F    
Sbjct: 82  D-RPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQV 137

Query: 314 IQNAVHCTDLPEDGLLEVQYFF 335
            +N +H +D  E    E+  +F
Sbjct: 138 GRNIIHGSDSVESAEKEIGLWF 159


>gi|4557797 non-metastatic cells 1, protein (NM23A) expressed in
           isoform b [Homo sapiens]
          Length = 152

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 47/150 (31%), Positives = 75/150 (50%), Gaps = 11/150 (7%)

Query: 56  EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 113
           E+T   IKPD + +   GEII+   + GF +  LK M  S     + +VD + RPFF  L
Sbjct: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGL 64

Query: 114 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 173
           ++++ +GP++AM     + +   + +LG  N   ++     +IR  F     RN  HG D
Sbjct: 65  VKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121

Query: 174 SFASAAREMELFFPSSGGCGPANTAKFTNC 203
           S  SA +E+ L+F       P     +T+C
Sbjct: 122 SVESAEKEIGLWF------HPEELVDYTSC 145



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 40/136 (29%), Positives = 62/136 (45%), Gaps = 6/136 (4%)

Query: 202 NC--TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEY 259
           NC  T   +KP  V  GL+G+I+      GF +  ++        ++E Y   K     +
Sbjct: 3   NCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKD-RPFF 61

Query: 260 HDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVH 319
             +V  M+SGP VAM  +  N  KT R   G  +P  +   +PGT+R  F     +N +H
Sbjct: 62  AGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIH 118

Query: 320 CTDLPEDGLLEVQYFF 335
            +D  E    E+  +F
Sbjct: 119 GSDSVESAEKEIGLWF 134


>gi|66392227 nucleoside diphosphate kinase B [Homo sapiens]
          Length = 152

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 5/133 (3%)

Query: 56  EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 113
           E+T   IKPD + +   GEII+   + GF +  +K +  S +     ++D + RPFF  L
Sbjct: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64

Query: 114 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 173
           ++++ +GP++AM     + +   + +LG  N   ++     +IR  F     RN  HG D
Sbjct: 65  VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121

Query: 174 SFASAAREMELFF 186
           S  SA +E+ L+F
Sbjct: 122 SVKSAEKEISLWF 134



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 4/133 (3%)

Query: 204 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 263
           T   +KP  V  GL+G+I+      GF + AM+       ++++ Y   K     +  +V
Sbjct: 7   TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKD-RPFFPGLV 65

Query: 264 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 323
             M SGP VAM  +  N  KT R   G  +P  +   +PGT+R  F     +N +H +D 
Sbjct: 66  KYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIHGSDS 122

Query: 324 PEDGLLEVQYFFK 336
            +    E+  +FK
Sbjct: 123 VKSAEKEISLWFK 135


>gi|66392205 nucleoside diphosphate kinase B [Homo sapiens]
          Length = 152

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 5/133 (3%)

Query: 56  EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 113
           E+T   IKPD + +   GEII+   + GF +  +K +  S +     ++D + RPFF  L
Sbjct: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64

Query: 114 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 173
           ++++ +GP++AM     + +   + +LG  N   ++     +IR  F     RN  HG D
Sbjct: 65  VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121

Query: 174 SFASAAREMELFF 186
           S  SA +E+ L+F
Sbjct: 122 SVKSAEKEISLWF 134



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 4/133 (3%)

Query: 204 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 263
           T   +KP  V  GL+G+I+      GF + AM+       ++++ Y   K     +  +V
Sbjct: 7   TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKD-RPFFPGLV 65

Query: 264 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 323
             M SGP VAM  +  N  KT R   G  +P  +   +PGT+R  F     +N +H +D 
Sbjct: 66  KYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIHGSDS 122

Query: 324 PEDGLLEVQYFFK 336
            +    E+  +FK
Sbjct: 123 VKSAEKEISLWFK 135


>gi|66392192 nucleoside diphosphate kinase B [Homo sapiens]
          Length = 152

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 5/133 (3%)

Query: 56  EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 113
           E+T   IKPD + +   GEII+   + GF +  +K +  S +     ++D + RPFF  L
Sbjct: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64

Query: 114 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 173
           ++++ +GP++AM     + +   + +LG  N   ++     +IR  F     RN  HG D
Sbjct: 65  VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121

Query: 174 SFASAAREMELFF 186
           S  SA +E+ L+F
Sbjct: 122 SVKSAEKEISLWF 134



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 4/133 (3%)

Query: 204 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 263
           T   +KP  V  GL+G+I+      GF + AM+       ++++ Y   K     +  +V
Sbjct: 7   TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKD-RPFFPGLV 65

Query: 264 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 323
             M SGP VAM  +  N  KT R   G  +P  +   +PGT+R  F     +N +H +D 
Sbjct: 66  KYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIHGSDS 122

Query: 324 PEDGLLEVQYFFK 336
            +    E+  +FK
Sbjct: 123 VKSAEKEISLWFK 135


>gi|4505409 nucleoside diphosphate kinase B [Homo sapiens]
          Length = 152

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 5/133 (3%)

Query: 56  EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 113
           E+T   IKPD + +   GEII+   + GF +  +K +  S +     ++D + RPFF  L
Sbjct: 5   ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64

Query: 114 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 173
           ++++ +GP++AM     + +   + +LG  N   ++     +IR  F     RN  HG D
Sbjct: 65  VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121

Query: 174 SFASAAREMELFF 186
           S  SA +E+ L+F
Sbjct: 122 SVKSAEKEISLWF 134



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 4/133 (3%)

Query: 204 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 263
           T   +KP  V  GL+G+I+      GF + AM+       ++++ Y   K     +  +V
Sbjct: 7   TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKD-RPFFPGLV 65

Query: 264 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 323
             M SGP VAM  +  N  KT R   G  +P  +   +PGT+R  F     +N +H +D 
Sbjct: 66  KYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIHGSDS 122

Query: 324 PEDGLLEVQYFFK 336
            +    E+  +FK
Sbjct: 123 VKSAEKEISLWFK 135


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 4/56 (7%)

Query: 287 EFCGPADPEIARHLRPGTLRAIFGKTKIQ----NAVHCTDLPEDGLLEVQYFFKIL 338
           +F G ADP +  HL PG  +A   KTK Q    N V   DL   G+ +     K+L
Sbjct: 120 DFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVL 175


>gi|112363080 microtubule associated serine/threonine kinase 2 [Homo
           sapiens]
          Length = 1798

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 287 EFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN 340
           EF     P+    L  G L  I  +  I+ A  C D    GL+  QYF+++ DN
Sbjct: 337 EFISSNTPDSVLPLADGALSFIHHQV-IEMARDCLDKSRSGLITSQYFYELQDN 389


>gi|191251777 breast carcinoma amplified sequence 1 [Homo sapiens]
          Length = 584

 Score = 29.3 bits (64), Expect = 5.3
 Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 6/57 (10%)

Query: 143 ANSGVARTDASES----IRALFGTDGIRNAAHGP--DSFASAAREMELFFPSSGGCG 193
           +N   A  D SES    + A  G D  +   H P  D   SAAR+  L  P +GG G
Sbjct: 125 SNKAPANKDPSESWTLPVAAGPGQDTDKTPGHAPAQDKVLSAARDPTLLPPETGGAG 181


>gi|11321597 kinase insert domain receptor precursor [Homo sapiens]
          Length = 1356

 Score = 28.5 bits (62), Expect = 9.0
 Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 1/58 (1%)

Query: 21  LEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISKAGEIIEIIN 78
           +ED   GNK+ V   Q  LI+ G   T   L  +     AL K +A++K G    +I+
Sbjct: 488 VEDFQGGNKIEVNKNQFALIE-GKNKTVSTLVIQAANVSALYKCEAVNKVGRGERVIS 544


>gi|21450729 hypothetical protein LOC219833 [Homo sapiens]
          Length = 145

 Score = 28.5 bits (62), Expect = 9.0
 Identities = 30/97 (30%), Positives = 36/97 (37%), Gaps = 21/97 (21%)

Query: 147 VARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPS---SGGCGPANTAKFTNC 203
           V  T  S S+R+   T  + N + G D  A   R  E    S   + GCG   +A  TN 
Sbjct: 42  VTPTGRSASVRSEGNTSSLWNFSAGQDVHAIVTRTCESVLSSAVYTHGCGCVRSA--TNI 99

Query: 204 TC----------------CIVKPHAVSEGLLGKILMA 224
           TC                 I K H   EG LG  L A
Sbjct: 100 TCQSSGQQRQAARQEEENSICKAHDSREGRLGYPLSA 136


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,001,447
Number of Sequences: 37866
Number of extensions: 484840
Number of successful extensions: 995
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 919
Number of HSP's gapped (non-prelim): 37
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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