Guide to the Human Genome
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Search of human proteins with 33620745

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo
sapiens]
         (1555 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap...  3179   0.0  
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   104   8e-22
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   104   8e-22
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   103   1e-21
gi|154759255 collagen, type XXVIII precursor [Homo sapiens]           102   3e-21
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      102   4e-21
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   101   5e-21
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   101   5e-21
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   101   6e-21
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   101   6e-21
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   101   6e-21
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    100   8e-21
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]       100   8e-21
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]       100   8e-21
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   100   1e-20
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      99   4e-20
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    99   4e-20
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    99   4e-20
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    99   4e-20
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                98   5e-20
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       97   9e-20
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                   97   9e-20
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    97   1e-19
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    97   1e-19
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               97   2e-19
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      96   4e-19
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      95   5e-19
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         94   8e-19
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          94   1e-18
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    94   1e-18

>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sapiens]
          Length = 1555

 Score = 3179 bits (8242), Expect = 0.0
 Identities = 1555/1555 (100%), Positives = 1555/1555 (100%)

Query: 1    MSEQTPAEAGAAGAREDACRDYQSSLEDLTFNSKPHINMLTILAEENLPFAKEIVSLIEA 60
            MSEQTPAEAGAAGAREDACRDYQSSLEDLTFNSKPHINMLTILAEENLPFAKEIVSLIEA
Sbjct: 1    MSEQTPAEAGAAGAREDACRDYQSSLEDLTFNSKPHINMLTILAEENLPFAKEIVSLIEA 60

Query: 61   QTAKAPSSEKLPVMYLMDSIVKNVGREYLTAFTKNLVATFICVFEKVDENTRKSLFKLRS 120
            QTAKAPSSEKLPVMYLMDSIVKNVGREYLTAFTKNLVATFICVFEKVDENTRKSLFKLRS
Sbjct: 61   QTAKAPSSEKLPVMYLMDSIVKNVGREYLTAFTKNLVATFICVFEKVDENTRKSLFKLRS 120

Query: 121  TWDEIFPLKKLYALDVRVNSLDPAWPIKPLPPNVNTSSIHVNPKFLNKSPEEPSTPGTVV 180
            TWDEIFPLKKLYALDVRVNSLDPAWPIKPLPPNVNTSSIHVNPKFLNKSPEEPSTPGTVV
Sbjct: 121  TWDEIFPLKKLYALDVRVNSLDPAWPIKPLPPNVNTSSIHVNPKFLNKSPEEPSTPGTVV 180

Query: 181  SSPSISTPPIVPDIQKNLTQEQLIRQQLLAKQKQLLELQQKKLELELEQAKAQLAVSLSV 240
            SSPSISTPPIVPDIQKNLTQEQLIRQQLLAKQKQLLELQQKKLELELEQAKAQLAVSLSV
Sbjct: 181  SSPSISTPPIVPDIQKNLTQEQLIRQQLLAKQKQLLELQQKKLELELEQAKAQLAVSLSV 240

Query: 241  QQETSNLGPGSAPSKLHVSQIPPMAVKAPHQVPVQSEKSRPGPSLQIQDLKGTNRDPRLN 300
            QQETSNLGPGSAPSKLHVSQIPPMAVKAPHQVPVQSEKSRPGPSLQIQDLKGTNRDPRLN
Sbjct: 241  QQETSNLGPGSAPSKLHVSQIPPMAVKAPHQVPVQSEKSRPGPSLQIQDLKGTNRDPRLN 300

Query: 301  RISQHSHGKDQSHRKEFLMNTLNQSDTKTSKTIPSEKLNSSKQEKSKSGEKITKKELDQL 360
            RISQHSHGKDQSHRKEFLMNTLNQSDTKTSKTIPSEKLNSSKQEKSKSGEKITKKELDQL
Sbjct: 301  RISQHSHGKDQSHRKEFLMNTLNQSDTKTSKTIPSEKLNSSKQEKSKSGEKITKKELDQL 360

Query: 361  DSKSKSKSKSPSPLKNKLSHTKDLKNQESESMRLSDMNKRDPRLKKHLQDKTDGKDDDVK 420
            DSKSKSKSKSPSPLKNKLSHTKDLKNQESESMRLSDMNKRDPRLKKHLQDKTDGKDDDVK
Sbjct: 361  DSKSKSKSKSPSPLKNKLSHTKDLKNQESESMRLSDMNKRDPRLKKHLQDKTDGKDDDVK 420

Query: 421  EKRKTAEKKDKDEHMKSSEHRLAGSRNKIINGIVQKQDTITEESEKQGTKPGRSSTRKRS 480
            EKRKTAEKKDKDEHMKSSEHRLAGSRNKIINGIVQKQDTITEESEKQGTKPGRSSTRKRS
Sbjct: 421  EKRKTAEKKDKDEHMKSSEHRLAGSRNKIINGIVQKQDTITEESEKQGTKPGRSSTRKRS 480

Query: 481  RSRSPKSRSPIIHSPKRRDRRSPKRRQRSMSPTSTPKAGKIRQSGAKQSHMEEFTPPSRE 540
            RSRSPKSRSPIIHSPKRRDRRSPKRRQRSMSPTSTPKAGKIRQSGAKQSHMEEFTPPSRE
Sbjct: 481  RSRSPKSRSPIIHSPKRRDRRSPKRRQRSMSPTSTPKAGKIRQSGAKQSHMEEFTPPSRE 540

Query: 541  DRNAKRSTKQDIRDPRRMKKTEEERPQETTNQHSTKSGTEPKENVENWQSSKSAKRWKSG 600
            DRNAKRSTKQDIRDPRRMKKTEEERPQETTNQHSTKSGTEPKENVENWQSSKSAKRWKSG
Sbjct: 541  DRNAKRSTKQDIRDPRRMKKTEEERPQETTNQHSTKSGTEPKENVENWQSSKSAKRWKSG 600

Query: 601  WEENKSLQQVDEHSKPPHLRHRESWSSTKGILSPRAPKQQQHRLSVDANLQIPKELTLAS 660
            WEENKSLQQVDEHSKPPHLRHRESWSSTKGILSPRAPKQQQHRLSVDANLQIPKELTLAS
Sbjct: 601  WEENKSLQQVDEHSKPPHLRHRESWSSTKGILSPRAPKQQQHRLSVDANLQIPKELTLAS 660

Query: 661  KRELLQKTSERLASGEITQDDFLVVVHQIRQLFQYQEGVREEQRSPFNDRFPLKRPRYED 720
            KRELLQKTSERLASGEITQDDFLVVVHQIRQLFQYQEGVREEQRSPFNDRFPLKRPRYED
Sbjct: 661  KRELLQKTSERLASGEITQDDFLVVVHQIRQLFQYQEGVREEQRSPFNDRFPLKRPRYED 720

Query: 721  SDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVARDGPTKMIFEGPNKLSPRI 780
            SDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVARDGPTKMIFEGPNKLSPRI
Sbjct: 721  SDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVARDGPTKMIFEGPNKLSPRI 780

Query: 781  DGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQ 840
            DGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQ
Sbjct: 781  DGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQ 840

Query: 841  AGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVG 900
            AGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVG
Sbjct: 841  AGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVG 900

Query: 901  GLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPH 960
            GLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPH
Sbjct: 901  GLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPH 960

Query: 961  GQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRI 1020
            GQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRI
Sbjct: 961  GQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRI 1020

Query: 1021 EGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPG 1080
            EGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPG
Sbjct: 1021 EGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPG 1080

Query: 1081 QQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPG 1140
            QQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPG
Sbjct: 1081 QQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPG 1140

Query: 1141 NAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQSFSNPLNRASGHYFDEKNLQSSQF 1200
            NAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQSFSNPLNRASGHYFDEKNLQSSQF
Sbjct: 1141 NAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQSFSNPLNRASGHYFDEKNLQSSQF 1200

Query: 1201 GNFGNIPAPMTVGNIQASQQVLSGVAQPVAFGQGQQFLPVHPQNPGFVQNPSGALPKAYP 1260
            GNFGNIPAPMTVGNIQASQQVLSGVAQPVAFGQGQQFLPVHPQNPGFVQNPSGALPKAYP
Sbjct: 1201 GNFGNIPAPMTVGNIQASQQVLSGVAQPVAFGQGQQFLPVHPQNPGFVQNPSGALPKAYP 1260

Query: 1261 DNHLSQVDVNELFSKLLKTGILKLSQTDSATTQVSEVTAQPPPEEEEDQNEDQDVPDLTN 1320
            DNHLSQVDVNELFSKLLKTGILKLSQTDSATTQVSEVTAQPPPEEEEDQNEDQDVPDLTN
Sbjct: 1261 DNHLSQVDVNELFSKLLKTGILKLSQTDSATTQVSEVTAQPPPEEEEDQNEDQDVPDLTN 1320

Query: 1321 FTVEELKQRYDSVINRLYTGIQCYSCGMRFTTSQTDVYADHLDWHYRQNRTEKDVSRKVT 1380
            FTVEELKQRYDSVINRLYTGIQCYSCGMRFTTSQTDVYADHLDWHYRQNRTEKDVSRKVT
Sbjct: 1321 FTVEELKQRYDSVINRLYTGIQCYSCGMRFTTSQTDVYADHLDWHYRQNRTEKDVSRKVT 1380

Query: 1381 HRRWYYSLTDWIEFEEIADLEERAKSQFFEKVHEEVVLKTQEAAKEKEFQSVPAGPAGAV 1440
            HRRWYYSLTDWIEFEEIADLEERAKSQFFEKVHEEVVLKTQEAAKEKEFQSVPAGPAGAV
Sbjct: 1381 HRRWYYSLTDWIEFEEIADLEERAKSQFFEKVHEEVVLKTQEAAKEKEFQSVPAGPAGAV 1440

Query: 1441 ESCEICQEQFEQYWDEEEEEWHLKNAIRVDGKIYHPSCYEDYQNTSSFDCTPSPSKTPVE 1500
            ESCEICQEQFEQYWDEEEEEWHLKNAIRVDGKIYHPSCYEDYQNTSSFDCTPSPSKTPVE
Sbjct: 1441 ESCEICQEQFEQYWDEEEEEWHLKNAIRVDGKIYHPSCYEDYQNTSSFDCTPSPSKTPVE 1500

Query: 1501 NPLNIMLNIVKNELQEPCDSPKVKEERIDTPPACTEESIATPSEIKTENDTVESV 1555
            NPLNIMLNIVKNELQEPCDSPKVKEERIDTPPACTEESIATPSEIKTENDTVESV
Sbjct: 1501 NPLNIMLNIVKNELQEPCDSPKVKEERIDTPPACTEESIATPSEIKTENDTVESV 1555


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  104 bits (259), Expect = 8e-22
 Identities = 146/474 (30%), Positives = 176/474 (37%), Gaps = 90/474 (18%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLR---- 833
            P + GPP P      G PGQ G  GP   +G  G +G   P   EGPPGP G P +    
Sbjct: 999  PGLPGPPGPKGN--PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056

Query: 834  -FEGPIGQAGGGGFRFEGSPGL-------RFEGSPGGLRFEGPGGQP-VGGL-RFEGHRG 883
               G  G  G  G    G PGL          G PG    +G  G P + GL    G +G
Sbjct: 1057 GLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKG 1116

Query: 884  QPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGI 941
            QP G   F G  G P G      P G P  GL  E G    G      GP G+ G  G  
Sbjct: 1117 QP-GLPGFPGTPGPP-GPKGISGPPGNP--GLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172

Query: 942  RFEGPLLQQG----VGMRFEGPHG-QSVAGLRFEGQHNQLGGNLRFEGPHGQPGV----G 992
               GP  Q+G     G    GP G   ++G + +G    + GN    GP G+PG     G
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 993  IR-------FEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFD-GQPG 1044
            ++         GP ++  G     GP  P G   + GP  +G P   G   ++ + G PG
Sbjct: 1233 VQGPPGPPGSPGPALE--GPKGNPGPQGPPGRPGLPGP--EGPPGLPGNGGIKGEKGNPG 1288

Query: 1045 QPSLLPRFDGLHGQPG-PRFERTPGQPGPQRFDGPPGQQVQPRFDGV------------- 1090
            QP  LP   GL G  G P  +  PG+PG     G PG    P F G+             
Sbjct: 1289 QPG-LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1347

Query: 1091 ----------PQRFDGPQHQ------QASRFDIP--LGLQGTRFDNHPSQRLESVSFNQT 1132
                      P    GP  Q       A    IP   GL+G      P Q L       T
Sbjct: 1348 GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP-QGLP----GPT 1402

Query: 1133 GPYNDPPGNAF--------NAPSQGLQFQRHEQIFDSPQGPN-FNGPHGPGNQS 1177
            GP  DP  N               GL  Q   +  D P GP+   GP GP   S
Sbjct: 1403 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTS 1456



 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 132/383 (34%), Positives = 156/383 (40%), Gaps = 73/383 (19%)

Query: 755  PSRPSVARDGPTKMIFEGPNKLSPRIDGPP----TPASLRFDGSPGQMGGGGPLRFEGPQ 810
            P  P +   GP      GP K  P I GPP    TP  +  +G PG  G      F GP+
Sbjct: 701  PGIPGIGLPGPP-----GP-KGFPGIPGPPGAPGTPGRIGLEGPPGPPG------FPGPK 748

Query: 811  GQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPG----LRFEGSPGGLRFE 866
            G+ G   P    GPPGP G P  F+G +G  G  GF   G PG       +G PG     
Sbjct: 749  GEPGFALP----GPPGPPGLP-GFKGALGPKGDRGF--PGPPGPPGRTGLDGLPGPKGDV 801

Query: 867  GPGGQP----VGGLRFEGHRGQPVGGLRFEGPHGQP----VGGLRFD-NPRGQPVGGLRF 917
            GP GQP      GL   G +G P G     GP GQP    + G + D  P G  V G   
Sbjct: 802  GPNGQPGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG 860

Query: 918  EGGHGPSGAAIRFDGPHGQPG-----GGIRFEGPLLQQGVGMRFEGPHG-------QSVA 965
            E G      A    GP G PG     G   F G   + G+ M   GP G         V 
Sbjct: 861  ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM-MGPPGPPGPLGIPGRSGVP 919

Query: 966  GLR----FEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEG-PSVPGGGL 1018
            GL+     +GQ    G  G    +G  G PG     +  L+   G     G P +PG   
Sbjct: 920  GLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG--- 976

Query: 1019 RIEGPLG-QGGPRFEGCHALRFDGQPGQPSLL-PRFD-GLHGQPG----PRFERTPGQ-- 1069
             + GP G QG P   G   L   GQPG P    P+ + GL GQPG    P  + T G   
Sbjct: 977  -VSGPKGYQGLPGDPGQPGL--SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 1070 -PGPQRFDGPPGQQVQPRFDGVP 1091
             PGPQ  +GPPG    P   G P
Sbjct: 1034 FPGPQGVEGPPGPSGVPGQPGSP 1056



 Score = 97.4 bits (241), Expect = 9e-20
 Identities = 150/489 (30%), Positives = 180/489 (36%), Gaps = 103/489 (21%)

Query: 711  FPLKRPRYEDSDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVARDGPTKMIF 770
            FP +R +  D   P +  P     GLD            P   GP  P+     P+  I 
Sbjct: 401  FPGERGQKGDEGPPGISIPGP--PGLDGQP-------GAPGLPGPPGPAGPHIPPSDEIC 451

Query: 771  EGPNKLSPRIDGPP-TPASLRFDGSPGQMGGGGPLRFE-------GPQGQLG-GGCPLRF 821
            E      P   GPP +P      G  G  G  G   F        GP GQ G  G P   
Sbjct: 452  E------PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP--- 502

Query: 822  EGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGH 881
             GPPG +G P + +G  GQAG  G +  G PG+   G+PG   F G  G+P   L F G 
Sbjct: 503  -GPPGSLGFPGQ-KGEKGQAGATGPK--GLPGI--PGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 882  RGQPVGGLRFEGPHGQPV--------GGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGP 933
            +G   G L   G  G P         G      P+G+P GG+ F+G  GP G      G 
Sbjct: 557  KGDK-GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEP-GGITFKGERGPPGNP----GL 610

Query: 934  HGQPGGGIRFEGPLLQQGVGMRFEGPHGQS-VAGLRFEGQHNQLGGNLRFEGPHGQPGVG 992
             G PG      GP+   G G    GP G+  + G+   G   Q G      GP G PG  
Sbjct: 611  PGLPGN----IGPMGPPGFGP--PGPVGEKGIQGVA--GNPGQPG----IPGPKGDPGQT 658

Query: 993  IRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRF 1052
            I   G             P +PG   R +G +G  G            G PGQP L P  
Sbjct: 659  ITQPGK------------PGLPGNPGR-DGDVGLPGD----------PGLPGQPGL-PGI 694

Query: 1053 DGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQR--FDGPQHQQASRFDIPLG 1110
             G  G+PG      PG PGP+ F G PG    P   G P R   +GP       F  P G
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPGIPG---PPGAPGTPGRIGLEGPPGPPG--FPGPKG 749

Query: 1111 LQGTRFDNHPSQRLESVSFNQTGPYND-----PPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
              G      P            GP  D     PPG        GL   + +       GP
Sbjct: 750  EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD------VGP 803

Query: 1166 NFN-GPHGP 1173
            N   GP GP
Sbjct: 804  NGQPGPMGP 812



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 123/379 (32%), Positives = 151/379 (39%), Gaps = 77/379 (20%)

Query: 780  IDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIG 839
            I GPP    L   G PG +GGGG     GP G+ G       +G PGP G     +G  G
Sbjct: 1135 ISGPPGNPGL--PGEPGPVGGGGHPGQPGPPGEKGKPGQ---DGIPGPAGQ----KGEPG 1185

Query: 840  QAGGGGFRFEGSPGLRFE-------GSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFE 892
            Q G G     G PGL  +       G PG     GP G+P G   F G +G P       
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP-GFHGFPGVQGPP------- 1237

Query: 893  GPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG----GGIRFE-GPL 947
            GP G P  G   + P+G P       G  GP G      GP G PG    GGI+ E G  
Sbjct: 1238 GPPGSP--GPALEGPKGNP-------GPQGPPGRP-GLPGPEGPPGLPGNGGIKGEKGNP 1287

Query: 948  LQQGV----GMRFE-GPHG-------QSVAGLRFEGQHNQLGGNLRFEGPHGQPG-VGIR 994
             Q G+    G++ + GP G         + G++ +     + G    +GP G PG  G  
Sbjct: 1288 GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1347

Query: 995  FEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGG----------PRFEGCHALRFD-GQP 1043
             E  L+   G     GPS  G  + I+G  G  G          P  +G   L    G P
Sbjct: 1348 GEPGLIGPPGPPGLPGPS--GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPP 1405

Query: 1044 GQPSL--LPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQ------VQPRFDGVPQRFD 1095
            G P    LP FDG  G+ G      PGQPG +  DGPPG          P    V   F 
Sbjct: 1406 GDPGRNGLPGFDGAGGRKGD--PGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFL 1463

Query: 1096 GPQHQQASRFDIPLGLQGT 1114
              +H Q +  D P   QGT
Sbjct: 1464 ITRHSQTT--DAPQCPQGT 1480



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 131/406 (32%), Positives = 158/406 (38%), Gaps = 64/406 (15%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P   G P    +   G PG  G  G     GP G  G    +  EGPPGP G    F GP
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPG---IPGPPGAPGTPGRIGLEGPPGPPG----FPGP 747

Query: 838  IGQAGGGGFRFEGSPGL-RFEGS--PGGLR-FEGPGGQPVGGLRFEGHRGQPVGGLRFEG 893
             G+ G       G PGL  F+G+  P G R F GP G P G    +G  G P G +   G
Sbjct: 748  KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP-GRTGLDGLPG-PKGDV---G 802

Query: 894  PHGQPVGGLRFDNPRGQP-VGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGV 952
            P+GQP        P G P + G+  +G  GP G      GP GQPG      G   ++G 
Sbjct: 803  PNGQP-------GPMGPPGLPGIGVQGPPGPPG----IPGPIGQPG----LHGIPGEKG- 846

Query: 953  GMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGV-GIRFEGPLVQQGGGMRFEGP 1011
                 GP G  V G   E     + G     GP G PG+ G           G M   GP
Sbjct: 847  ---DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 1012 SVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPG 1071
              P G L I G    G P  +G   L+  GQPG P       G  G+PG      PG PG
Sbjct: 904  PGPPGPLGIPG--RSGVPGLKGDDGLQ--GQPGLPGPTGE-KGSKGEPG-----LPGPPG 953

Query: 1072 PQ--RFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSF 1129
            P      G  G++ +P   G+P    GP+  Q        GL G      P    +    
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGIP-GVSGPKGYQ--------GLPGD--PGQPGLSGQPGLP 1002

Query: 1130 NQTGPYNDP--PGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGP 1173
               GP  +P  PG        GL+    +  F  PQG    GP GP
Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQG--VEGPPGP 1046



 Score = 92.0 bits (227), Expect = 4e-18
 Identities = 132/438 (30%), Positives = 167/438 (38%), Gaps = 91/438 (20%)

Query: 792  DGSPGQMGGGGPLRFEGPQGQLGG-GCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEG 850
            +G PG  G  GP    GP+GQ G  G P    GPPGP G      GP G  G     F G
Sbjct: 56   EGHPGLPGFPGPEGPPGPRGQKGDDGIP----GPPGPKG----IRGPPGLPG-----FPG 102

Query: 851  SPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP--VGGLRFEGPHGQP-VGGLR---- 903
            +PGL   G PG     GP G P G    +G RG P   G    +GP G P + G++    
Sbjct: 103  TPGL--PGMPGHDGAPGPQGIP-GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPG 159

Query: 904  ------FDNPRGQP--VGGLRFEGGHGPSGAAIRFDGPHGQPG--------GGIRFEGPL 947
                     P+G P   G    +G  GP+G      GP G PG        G     GP 
Sbjct: 160  SIIMSSLPGPKGNPGYPGPPGIQGLPGPTG----IPGPIGPPGPPGLMGPPGPPGLPGP- 214

Query: 948  LQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPL--VQQGGG 1005
             +  +G+ F+GP G+               G    +GP G PG     + P+    Q G 
Sbjct: 215  -KGNMGLNFQGPKGEK--------------GEQGLQGPPGPPGQISEQKRPIDVEFQKGD 259

Query: 1006 MRFEGPSVPGGGLRIEGPLG-QGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPG-PRF 1063
                G   P G   I GP G  GG + E        G+PG+    P  DG +GQPG P  
Sbjct: 260  QGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE----QGEPGKRG-KPGKDGENGQPGIPGL 314

Query: 1064 ERTPGQPGPQRFDGPPGQQVQPRFDG-----VPQRFDGPQHQQASRFDIPLGLQGTRFDN 1118
               PG PG    DG  GQ+      G     +P+   G    +     +P GL       
Sbjct: 315  PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLP-GL------- 366

Query: 1119 HPSQRLESVSFNQTGP--YNDPPGNAFNAP--SQGLQFQRHEQIFDSPQGPNFNGPHG-- 1172
             P ++ E       GP     PPG A   P    G   +R ++  + P G +  GP G  
Sbjct: 367  -PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD 425

Query: 1173 --PGNQSFSNPLNRASGH 1188
              PG      P   A  H
Sbjct: 426  GQPGAPGLPGPPGPAGPH 443



 Score = 91.3 bits (225), Expect = 7e-18
 Identities = 127/410 (30%), Positives = 158/410 (38%), Gaps = 94/410 (22%)

Query: 777  SPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEG 836
            +P + G P P      G  G  G  GP   +G  GQ         +G PGP G     +G
Sbjct: 1141 NPGLPGEPGPV-----GGGGHPGQPGPPGEKGKPGQ---------DGIPGPAGQ----KG 1182

Query: 837  PIGQAGGGGFRFEGSPGLR-------FEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGL 889
              GQ G G     G PGL          G PG     GP G+P G   F G +G P    
Sbjct: 1183 EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP-GFHGFPGVQGPP---- 1237

Query: 890  RFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG----GGIRFEG 945
               GP G P  G   + P+G P       G  GP G      GP G PG    GGI+ E 
Sbjct: 1238 ---GPPGSP--GPALEGPKGNP-------GPQGPPGRP-GLPGPEGPPGLPGNGGIKGE- 1283

Query: 946  PLLQQGVGMRFEGPHGQ-SVAGL-RFEGQHNQLGGNLRFEGPHGQPGV-GIRFEGPLVQQ 1002
                       +G  GQ  + GL   +G     G     +G  G+PG+ G++ +  L   
Sbjct: 1284 -----------KGNPGQPGLPGLPGLKGDQGPPG----LQGNPGRPGLNGMKGDPGLPGV 1328

Query: 1003 GGGMRFEGPS-VPG-----GGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLH 1056
             G    +GPS VPG     G   + GP G  G       ++   G  G P  +P   GL 
Sbjct: 1329 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPG-IPGQPGLK 1387

Query: 1057 GQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTR- 1115
            G PGP  +   G PGP    G PG+   P FDG   R   P         +P G  GTR 
Sbjct: 1388 GLPGP--QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP--------GLP-GQPGTRG 1436

Query: 1116 FDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
             D  P            GP   PPG   ++ + G    RH Q  D+PQ P
Sbjct: 1437 LDGPPGPD------GLQGP-PGPPGT--SSVAHGFLITRHSQTTDAPQCP 1477



 Score = 87.8 bits (216), Expect = 7e-17
 Identities = 134/414 (32%), Positives = 155/414 (37%), Gaps = 103/414 (24%)

Query: 750  PLFDGPS-RPSVARDGPTKMIFEGP-------NKLSPRID----GPP-TPASLRFDGSPG 796
            P F GP   P  A  GP      GP         L P+ D    GPP  P     DG PG
Sbjct: 742  PGFPGPKGEPGFALPGPP-----GPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796

Query: 797  QMGGGGPLRFEGPQGQLGGGCP-LRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE----GS 851
              G  GP    GP G    G P +  +GPPGP G P    GPIGQ G  G   E    G 
Sbjct: 797  PKGDVGPNGQPGPMGP--PGLPGIGVQGPPGPPGIP----GPIGQPGLHGIPGEKGDPGP 850

Query: 852  PGLRFEGSPGGLRFEGPGGQP--------------VGGLRFEGHRGQ--------PVGGL 889
            PGL   G PG     G  G P               G   F G +G+        P G L
Sbjct: 851  PGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 890  RFEGPHGQPVGGLRFDNP-RGQP--------VGGLRFEGGHGPSGAA----IRFDGPHGQ 936
               G  G P  GL+ D+  +GQP         G     G  GP G      +   G  G+
Sbjct: 911  GIPGRSGVP--GLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGE 968

Query: 937  PG--GGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIR 994
            PG  G     GP   QG+     G  GQ   GL   GQ    G      GP G PG+  +
Sbjct: 969  PGLPGIPGVSGPKGYQGL----PGDPGQP--GL--SGQPGLPGP----PGPKGNPGLPGQ 1016

Query: 995  --FEGPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGG----PRFEGCHALRFD-GQPGQ 1045
                GP   +G  G M F GP        +EGP G  G    P   G    + D G PG 
Sbjct: 1017 PGLIGPPGLKGTIGDMGFPGPQ------GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 1046 PSL-LPRFDGLHGQPG-------PRFERTPGQPGPQRFDGPPGQQVQPRFDGVP 1091
             S+ LP   G  G+PG       P  + + G PG     G PG + QP   G P
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124



 Score = 81.3 bits (199), Expect = 7e-15
 Identities = 147/513 (28%), Positives = 182/513 (35%), Gaps = 112/513 (21%)

Query: 750  PLFDGPSRPSVAR-----DG----PTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGG 800
            P F GP  P   R     DG    P      GP  L      P  P     DG+PG  G 
Sbjct: 62   PGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI 121

Query: 801  GGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP-----------LRFEGPIGQAGGGGFRFE 849
             G    +G +G  G       +GPPGP G P               GP G  G     + 
Sbjct: 122  PGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPG-----YP 176

Query: 850  GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP-------VGGLRFEGPHGQPVGGL 902
            G PG+  +G PG     GP G P G     G  G P         GL F+GP G+  G  
Sbjct: 177  GPPGI--QGLPGPTGIPGPIGPP-GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK-GEQ 232

Query: 903  RFDNPRGQP---------------VGGLRFEGGHGPSG-AAIRFDGPHGQPGGGIRFEGP 946
                P G P                G     G  GP G   IR  GP G PGG    +G 
Sbjct: 233  GLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR--GPPGPPGGEKGEKGE 290

Query: 947  LLQQGVGMR--FEGPHGQ-SVAGL----RFEGQHNQLG--GNLRFEGPHGQPGVGIRFEG 997
              + G   +   +G +GQ  + GL     + G+  + G  G     GP G PG+ I   G
Sbjct: 291  QGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPG 350

Query: 998  PLVQQGGGMRFEGPSVPG-----GGLRIEGPLGQGGPRFEGCHALRFDGQPGQPS----- 1047
              +  G       P +PG     G   I+GP G  GP   G   +   G PG P      
Sbjct: 351  TGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP--PGAAVMGPPGPPGFPGERGQK 408

Query: 1048 --------LLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQH 1099
                     +P   GL GQPG      PG PGP    GP G  + P  D + +   GP  
Sbjct: 409  GDEGPPGISIPGPPGLDGQPG-----APGLPGP---PGPAGPHIPPS-DEICE--PGPPG 457

Query: 1100 QQASRFDIPL-GLQGTRFDNHPSQRLESVSFNQTGPYNDP--PGNAFNAPSQGLQFQRHE 1156
               S  D  L G QG + D   +     +    +GP   P  PG      S G   Q+ E
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDT-CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516

Query: 1157 Q-------------IFDSPQGPNFNGPHG-PGN 1175
            +             I  +P  P F G  G PG+
Sbjct: 517  KGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD 549



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 39/125 (31%), Positives = 47/125 (37%), Gaps = 23/125 (18%)

Query: 1054 GLHGQPG----PRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPL 1109
            G+ G+ G    P  E  PG PG    +GPPG + Q   DG+P    GP   +  R   P 
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIP----GPPGPKGIRG--PP 95

Query: 1110 GLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIF-DSPQGPNFN 1168
            GL G  F   P            GP   P          G    + E+ F  SP  P   
Sbjct: 96   GLPG--FPGTPGLPGMPGHDGAPGPQGIP----------GCNGTKGERGFPGSPGFPGLQ 143

Query: 1169 GPHGP 1173
            GP GP
Sbjct: 144  GPPGP 148



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 5/64 (7%)

Query: 771  EGPNKLSPRIDGPPTPASLR----FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPG 826
            +GP  L P   GPP          FDG+ G+ G  G     G +G  G   P   +GPPG
Sbjct: 1393 QGPQGL-PGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1451

Query: 827  PVGT 830
            P GT
Sbjct: 1452 PPGT 1455


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  104 bits (259), Expect = 8e-22
 Identities = 149/477 (31%), Positives = 176/477 (36%), Gaps = 93/477 (19%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLR---- 833
            P + GPP P      G PGQ G  GP   +G  G +G   P   EGPPGP G P +    
Sbjct: 999  PGLPGPPGPKGN--PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056

Query: 834  -FEGPIGQAGGGGFRFEGSPGL-------RFEGSPGGLRFEGPGGQP-VGGL-RFEGHRG 883
               G  G  G  G    G PGL          G PG    +G  G P + GL    G +G
Sbjct: 1057 GLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKG 1116

Query: 884  QPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGI 941
            QP G   F G  G P G      P G P  GL  E G    G      GP G+ G  G  
Sbjct: 1117 QP-GLPGFPGTPGPP-GPKGISGPPGNP--GLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172

Query: 942  RFEGPLLQQG----VGMRFEGPHG-QSVAGLRFEGQHNQLGGNLRFEGPHGQPGV----- 991
               GP  Q+G     G    GP G   ++G + +G    + GN    GP G+PG      
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 992  -----------GIRFEGPLVQQG-----GGMRFEG-------PSVPGGGLRIEGPLGQ-G 1027
                       G   EGP    G     G   F+G       P +PG G  I+G  G  G
Sbjct: 1233 VQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNG-GIKGEKGNPG 1291

Query: 1028 GPRFEGCHALRFD-------GQPGQPSLLPRFDGLHGQPG-PRFERTPGQPGPQRFDGPP 1079
             P   G   L+ D       G PG+P L    +G+ G PG P     PG  GP    G  
Sbjct: 1292 QPGLPGLPGLKGDQGPPGLQGNPGRPGL----NGMKGDPGLPGVPGFPGMKGPSGVPGSA 1347

Query: 1080 GQQVQPRFDGV--PQRFDGPQHQ------QASRFDIP--LGLQGTRFDNHPSQRLESVSF 1129
            G + +P   G   P    GP  Q       A    IP   GL+G      P Q L     
Sbjct: 1348 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP-QGLP---- 1402

Query: 1130 NQTGPYNDPPGNAF--------NAPSQGLQFQRHEQIFDSPQGPN-FNGPHGPGNQS 1177
              TGP  DP  N               GL  Q   +  D P GP+   GP GP   S
Sbjct: 1403 GPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTS 1459



 Score = 97.4 bits (241), Expect = 9e-20
 Identities = 150/489 (30%), Positives = 180/489 (36%), Gaps = 103/489 (21%)

Query: 711  FPLKRPRYEDSDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVARDGPTKMIF 770
            FP +R +  D   P +  P     GLD            P   GP  P+     P+  I 
Sbjct: 401  FPGERGQKGDEGPPGISIPGP--PGLDGQP-------GAPGLPGPPGPAGPHIPPSDEIC 451

Query: 771  EGPNKLSPRIDGPP-TPASLRFDGSPGQMGGGGPLRFE-------GPQGQLG-GGCPLRF 821
            E      P   GPP +P      G  G  G  G   F        GP GQ G  G P   
Sbjct: 452  E------PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP--- 502

Query: 822  EGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGH 881
             GPPG +G P + +G  GQAG  G +  G PG+   G+PG   F G  G+P   L F G 
Sbjct: 503  -GPPGSLGFPGQ-KGEKGQAGATGPK--GLPGI--PGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 882  RGQPVGGLRFEGPHGQPV--------GGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGP 933
            +G   G L   G  G P         G      P+G+P GG+ F+G  GP G      G 
Sbjct: 557  KGDK-GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEP-GGITFKGERGPPGNP----GL 610

Query: 934  HGQPGGGIRFEGPLLQQGVGMRFEGPHGQS-VAGLRFEGQHNQLGGNLRFEGPHGQPGVG 992
             G PG      GP+   G G    GP G+  + G+   G   Q G      GP G PG  
Sbjct: 611  PGLPGN----IGPMGPPGFGP--PGPVGEKGIQGVA--GNPGQPG----IPGPKGDPGQT 658

Query: 993  IRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRF 1052
            I   G             P +PG   R +G +G  G            G PGQP L P  
Sbjct: 659  ITQPGK------------PGLPGNPGR-DGDVGLPGD----------PGLPGQPGL-PGI 694

Query: 1053 DGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQR--FDGPQHQQASRFDIPLG 1110
             G  G+PG      PG PGP+ F G PG    P   G P R   +GP       F  P G
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPGIPG---PPGAPGTPGRIGLEGPPGPPG--FPGPKG 749

Query: 1111 LQGTRFDNHPSQRLESVSFNQTGPYND-----PPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
              G      P            GP  D     PPG        GL   + +       GP
Sbjct: 750  EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD------VGP 803

Query: 1166 NFN-GPHGP 1173
            N   GP GP
Sbjct: 804  NGQPGPMGP 812



 Score = 94.4 bits (233), Expect = 8e-19
 Identities = 125/380 (32%), Positives = 154/380 (40%), Gaps = 76/380 (20%)

Query: 780  IDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIG 839
            I GPP    L   G PG +GGGG     GP G+ G       +G PGP G     +G  G
Sbjct: 1135 ISGPPGNPGL--PGEPGPVGGGGHPGQPGPPGEKGKPGQ---DGIPGPAGQ----KGEPG 1185

Query: 840  QAGGGGFRFEGSPGLRFE-------GSPGGLRFEGPGGQPVGGLRFEGHRGQP----VGG 888
            Q G G     G PGL  +       G PG     GP G+P G   F G +G P      G
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP-GFHGFPGVQGPPGPPGSPG 1244

Query: 889  LRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG-GGIRFE-GP 946
               EGP G P        P+G P G   F+G  GP       +GP G PG GGI+ E G 
Sbjct: 1245 PALEGPKGNP-------GPQGPP-GRPGFQGLPGP-------EGPPGLPGNGGIKGEKGN 1289

Query: 947  LLQQGV----GMRFE-GPHG-------QSVAGLRFEGQHNQLGGNLRFEGPHGQPG-VGI 993
              Q G+    G++ + GP G         + G++ +     + G    +GP G PG  G 
Sbjct: 1290 PGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP 1349

Query: 994  RFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGG----------PRFEGCHALRFD-GQ 1042
              E  L+   G     GPS  G  + I+G  G  G          P  +G   L    G 
Sbjct: 1350 EGEPGLIGPPGPPGLPGPS--GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1407

Query: 1043 PGQPSL--LPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQ------VQPRFDGVPQRF 1094
            PG P    LP FDG  G+ G      PGQPG +  DGPPG          P    V   F
Sbjct: 1408 PGDPGRNGLPGFDGAGGRKGD--PGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGF 1465

Query: 1095 DGPQHQQASRFDIPLGLQGT 1114
               +H Q +  D P   QGT
Sbjct: 1466 LITRHSQTT--DAPQCPQGT 1483



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 130/406 (32%), Positives = 161/406 (39%), Gaps = 83/406 (20%)

Query: 777  SPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVG----TPL 832
            +P + G P P      G  G  G  GP   +G  GQ G   P   +G PG  G     P 
Sbjct: 1141 NPGLPGEPGPV-----GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195

Query: 833  RFEGPIGQAGGGGF-RFEGSPGLRF-EGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLR 890
               G  GQ G GG     G+PGL   +G PG   F G  G P       G  G P  G  
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPP-------GPPGSP--GPA 1246

Query: 891  FEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG-GGIRFEGPLLQ 949
             EGP G P        P+G P G   F+G  GP       +GP G PG GGI+ E     
Sbjct: 1247 LEGPKGNP-------GPQGPP-GRPGFQGLPGP-------EGPPGLPGNGGIKGE----- 1286

Query: 950  QGVGMRFEGPHGQ-SVAGL-RFEGQHNQLGGNLRFEGPHGQPGV-GIRFEGPLVQQGGGM 1006
                   +G  GQ  + GL   +G     G     +G  G+PG+ G++ +  L    G  
Sbjct: 1287 -------KGNPGQPGLPGLPGLKGDQGPPG----LQGNPGRPGLNGMKGDPGLPGVPGFP 1335

Query: 1007 RFEGPS-VPG-----GGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPG 1060
              +GPS VPG     G   + GP G  G       ++   G  G P  +P   GL G PG
Sbjct: 1336 GMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPG-IPGQPGLKGLPG 1394

Query: 1061 PRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTR-FDNH 1119
            P  +   G PGP    G PG+   P FDG   R   P         +P G  GTR  D  
Sbjct: 1395 P--QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP--------GLP-GQPGTRGLDGP 1443

Query: 1120 PSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
            P            GP   PPG   ++ + G    RH Q  D+PQ P
Sbjct: 1444 PGPD------GLQGP-PGPPGT--SSVAHGFLITRHSQTTDAPQCP 1480



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 131/406 (32%), Positives = 158/406 (38%), Gaps = 64/406 (15%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P   G P    +   G PG  G  G     GP G  G    +  EGPPGP G    F GP
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPG---IPGPPGAPGTPGRIGLEGPPGPPG----FPGP 747

Query: 838  IGQAGGGGFRFEGSPGL-RFEGS--PGGLR-FEGPGGQPVGGLRFEGHRGQPVGGLRFEG 893
             G+ G       G PGL  F+G+  P G R F GP G P G    +G  G P G +   G
Sbjct: 748  KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP-GRTGLDGLPG-PKGDV---G 802

Query: 894  PHGQPVGGLRFDNPRGQP-VGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGV 952
            P+GQP        P G P + G+  +G  GP G      GP GQPG      G   ++G 
Sbjct: 803  PNGQP-------GPMGPPGLPGIGVQGPPGPPG----IPGPIGQPG----LHGIPGEKG- 846

Query: 953  GMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGV-GIRFEGPLVQQGGGMRFEGP 1011
                 GP G  V G   E     + G     GP G PG+ G           G M   GP
Sbjct: 847  ---DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 1012 SVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPG 1071
              P G L I G    G P  +G   L+  GQPG P       G  G+PG      PG PG
Sbjct: 904  PGPPGPLGIPG--RSGVPGLKGDDGLQ--GQPGLPGPTGE-KGSKGEPG-----LPGPPG 953

Query: 1072 PQ--RFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSF 1129
            P      G  G++ +P   G+P    GP+  Q        GL G      P    +    
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGIP-GVSGPKGYQ--------GLPGD--PGQPGLSGQPGLP 1002

Query: 1130 NQTGPYNDP--PGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGP 1173
               GP  +P  PG        GL+    +  F  PQG    GP GP
Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQG--VEGPPGP 1046



 Score = 92.0 bits (227), Expect = 4e-18
 Identities = 132/438 (30%), Positives = 167/438 (38%), Gaps = 91/438 (20%)

Query: 792  DGSPGQMGGGGPLRFEGPQGQLGG-GCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEG 850
            +G PG  G  GP    GP+GQ G  G P    GPPGP G      GP G  G     F G
Sbjct: 56   EGHPGLPGFPGPEGPPGPRGQKGDDGIP----GPPGPKG----IRGPPGLPG-----FPG 102

Query: 851  SPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP--VGGLRFEGPHGQP-VGGLR---- 903
            +PGL   G PG     GP G P G    +G RG P   G    +GP G P + G++    
Sbjct: 103  TPGL--PGMPGHDGAPGPQGIP-GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPG 159

Query: 904  ------FDNPRGQP--VGGLRFEGGHGPSGAAIRFDGPHGQPG--------GGIRFEGPL 947
                     P+G P   G    +G  GP+G      GP G PG        G     GP 
Sbjct: 160  SIIMSSLPGPKGNPGYPGPPGIQGLPGPTG----IPGPIGPPGPPGLMGPPGPPGLPGP- 214

Query: 948  LQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPL--VQQGGG 1005
             +  +G+ F+GP G+               G    +GP G PG     + P+    Q G 
Sbjct: 215  -KGNMGLNFQGPKGEK--------------GEQGLQGPPGPPGQISEQKRPIDVEFQKGD 259

Query: 1006 MRFEGPSVPGGGLRIEGPLG-QGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPG-PRF 1063
                G   P G   I GP G  GG + E        G+PG+    P  DG +GQPG P  
Sbjct: 260  QGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE----QGEPGKRG-KPGKDGENGQPGIPGL 314

Query: 1064 ERTPGQPGPQRFDGPPGQQVQPRFDG-----VPQRFDGPQHQQASRFDIPLGLQGTRFDN 1118
               PG PG    DG  GQ+      G     +P+   G    +     +P GL       
Sbjct: 315  PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLP-GL------- 366

Query: 1119 HPSQRLESVSFNQTGP--YNDPPGNAFNAP--SQGLQFQRHEQIFDSPQGPNFNGPHG-- 1172
             P ++ E       GP     PPG A   P    G   +R ++  + P G +  GP G  
Sbjct: 367  -PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD 425

Query: 1173 --PGNQSFSNPLNRASGH 1188
              PG      P   A  H
Sbjct: 426  GQPGAPGLPGPPGPAGPH 443



 Score = 81.3 bits (199), Expect = 7e-15
 Identities = 147/513 (28%), Positives = 182/513 (35%), Gaps = 112/513 (21%)

Query: 750  PLFDGPSRPSVAR-----DG----PTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGG 800
            P F GP  P   R     DG    P      GP  L      P  P     DG+PG  G 
Sbjct: 62   PGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI 121

Query: 801  GGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP-----------LRFEGPIGQAGGGGFRFE 849
             G    +G +G  G       +GPPGP G P               GP G  G     + 
Sbjct: 122  PGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPG-----YP 176

Query: 850  GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP-------VGGLRFEGPHGQPVGGL 902
            G PG+  +G PG     GP G P G     G  G P         GL F+GP G+  G  
Sbjct: 177  GPPGI--QGLPGPTGIPGPIGPP-GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK-GEQ 232

Query: 903  RFDNPRGQP---------------VGGLRFEGGHGPSG-AAIRFDGPHGQPGGGIRFEGP 946
                P G P                G     G  GP G   IR  GP G PGG    +G 
Sbjct: 233  GLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR--GPPGPPGGEKGEKGE 290

Query: 947  LLQQGVGMR--FEGPHGQ-SVAGL----RFEGQHNQLG--GNLRFEGPHGQPGVGIRFEG 997
              + G   +   +G +GQ  + GL     + G+  + G  G     GP G PG+ I   G
Sbjct: 291  QGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPG 350

Query: 998  PLVQQGGGMRFEGPSVPG-----GGLRIEGPLGQGGPRFEGCHALRFDGQPGQPS----- 1047
              +  G       P +PG     G   I+GP G  GP   G   +   G PG P      
Sbjct: 351  TGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP--PGAAVMGPPGPPGFPGERGQK 408

Query: 1048 --------LLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQH 1099
                     +P   GL GQPG      PG PGP    GP G  + P  D + +   GP  
Sbjct: 409  GDEGPPGISIPGPPGLDGQPG-----APGLPGP---PGPAGPHIPPS-DEICE--PGPPG 457

Query: 1100 QQASRFDIPL-GLQGTRFDNHPSQRLESVSFNQTGPYNDP--PGNAFNAPSQGLQFQRHE 1156
               S  D  L G QG + D   +     +    +GP   P  PG      S G   Q+ E
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDT-CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516

Query: 1157 Q-------------IFDSPQGPNFNGPHG-PGN 1175
            +             I  +P  P F G  G PG+
Sbjct: 517  KGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD 549



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 39/125 (31%), Positives = 47/125 (37%), Gaps = 23/125 (18%)

Query: 1054 GLHGQPG----PRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPL 1109
            G+ G+ G    P  E  PG PG    +GPPG + Q   DG+P    GP   +  R   P 
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIP----GPPGPKGIRG--PP 95

Query: 1110 GLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIF-DSPQGPNFN 1168
            GL G  F   P            GP   P          G    + E+ F  SP  P   
Sbjct: 96   GLPG--FPGTPGLPGMPGHDGAPGPQGIP----------GCNGTKGERGFPGSPGFPGLQ 143

Query: 1169 GPHGP 1173
            GP GP
Sbjct: 144  GPPGP 148



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 5/64 (7%)

Query: 771  EGPNKLSPRIDGPPTPASLR----FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPG 826
            +GP  L P   GPP          FDG+ G+ G  G     G +G  G   P   +GPPG
Sbjct: 1396 QGPQGL-PGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1454

Query: 827  PVGT 830
            P GT
Sbjct: 1455 PPGT 1458


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  103 bits (257), Expect = 1e-21
 Identities = 152/478 (31%), Positives = 176/478 (36%), Gaps = 92/478 (19%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLR---- 833
            P + GPP P      G PGQ G  GP   +G  G +G   P   EGPPGP G P +    
Sbjct: 999  PGLPGPPGPKGN--PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056

Query: 834  -FEGPIGQAGGGGFRFEGSPGL-------RFEGSPGGLRFEGPGGQP-VGGL-RFEGHRG 883
               G  G  G  G    G PGL          G PG    +G  G P + GL    G +G
Sbjct: 1057 GLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKG 1116

Query: 884  QPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGI 941
            QP G   F G  G P G      P G P  GL  E G    G      GP G+ G  G  
Sbjct: 1117 QP-GLPGFPGTPGPP-GPKGISGPPGNP--GLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172

Query: 942  RFEGPLLQQG----VGMRFEGPHG-QSVAGLRFEGQHNQLGGNLRFEGPHGQPGV----G 992
               GP  Q+G     G    GP G   ++G + +G    + GN    GP G+PG     G
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 993  IRFEGPLVQQGG-GMRFEGPS---VPGGGLRIEGPLG-QGGPRFEGCHALRFD------- 1040
            +  +GP    G  G   EGP     P G     GP G QG P  EG   L  +       
Sbjct: 1233 V--QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEK 1290

Query: 1041 GQPGQPSLLPRFDGLHGQPG-PRFERTPGQPGPQRFDGPPGQQVQPRFDGV--------- 1090
            G PGQP  LP   GL G  G P  +  PG+PG     G PG    P F G+         
Sbjct: 1291 GNPGQPG-LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1349

Query: 1091 --------------PQRFDGPQHQ------QASRFDIP--LGLQGTRFDNHPSQRLESVS 1128
                          P    GP  Q       A    IP   GL+G      P Q L    
Sbjct: 1350 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP-QGLP--- 1405

Query: 1129 FNQTGPYNDPPGNAF--------NAPSQGLQFQRHEQIFDSPQGPN-FNGPHGPGNQS 1177
               TGP  DP  N               GL  Q   +  D P GP+   GP GP   S
Sbjct: 1406 -GPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTS 1462



 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 132/383 (34%), Positives = 156/383 (40%), Gaps = 73/383 (19%)

Query: 755  PSRPSVARDGPTKMIFEGPNKLSPRIDGPP----TPASLRFDGSPGQMGGGGPLRFEGPQ 810
            P  P +   GP      GP K  P I GPP    TP  +  +G PG  G      F GP+
Sbjct: 701  PGIPGIGLPGPP-----GP-KGFPGIPGPPGAPGTPGRIGLEGPPGPPG------FPGPK 748

Query: 811  GQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPG----LRFEGSPGGLRFE 866
            G+ G   P    GPPGP G P  F+G +G  G  GF   G PG       +G PG     
Sbjct: 749  GEPGFALP----GPPGPPGLP-GFKGALGPKGDRGF--PGPPGPPGRTGLDGLPGPKGDV 801

Query: 867  GPGGQP----VGGLRFEGHRGQPVGGLRFEGPHGQP----VGGLRFD-NPRGQPVGGLRF 917
            GP GQP      GL   G +G P G     GP GQP    + G + D  P G  V G   
Sbjct: 802  GPNGQPGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPG 860

Query: 918  EGGHGPSGAAIRFDGPHGQPG-----GGIRFEGPLLQQGVGMRFEGPHG-------QSVA 965
            E G      A    GP G PG     G   F G   + G+ M   GP G         V 
Sbjct: 861  ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM-MGPPGPPGPLGIPGRSGVP 919

Query: 966  GLR----FEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEG-PSVPGGGL 1018
            GL+     +GQ    G  G    +G  G PG     +  L+   G     G P +PG   
Sbjct: 920  GLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG--- 976

Query: 1019 RIEGPLG-QGGPRFEGCHALRFDGQPGQPSLL-PRFD-GLHGQPG----PRFERTPGQ-- 1069
             + GP G QG P   G   L   GQPG P    P+ + GL GQPG    P  + T G   
Sbjct: 977  -VSGPKGYQGLPGDPGQPGL--SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 1070 -PGPQRFDGPPGQQVQPRFDGVP 1091
             PGPQ  +GPPG    P   G P
Sbjct: 1034 FPGPQGVEGPPGPSGVPGQPGSP 1056



 Score = 97.4 bits (241), Expect = 9e-20
 Identities = 150/489 (30%), Positives = 180/489 (36%), Gaps = 103/489 (21%)

Query: 711  FPLKRPRYEDSDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVARDGPTKMIF 770
            FP +R +  D   P +  P     GLD            P   GP  P+     P+  I 
Sbjct: 401  FPGERGQKGDEGPPGISIPGP--PGLDGQP-------GAPGLPGPPGPAGPHIPPSDEIC 451

Query: 771  EGPNKLSPRIDGPP-TPASLRFDGSPGQMGGGGPLRFE-------GPQGQLG-GGCPLRF 821
            E      P   GPP +P      G  G  G  G   F        GP GQ G  G P   
Sbjct: 452  E------PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP--- 502

Query: 822  EGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGH 881
             GPPG +G P + +G  GQAG  G +  G PG+   G+PG   F G  G+P   L F G 
Sbjct: 503  -GPPGSLGFPGQ-KGEKGQAGATGPK--GLPGI--PGAPGAPGFPGSKGEPGDILTFPGM 556

Query: 882  RGQPVGGLRFEGPHGQPV--------GGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGP 933
            +G   G L   G  G P         G      P+G+P GG+ F+G  GP G      G 
Sbjct: 557  KGDK-GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEP-GGITFKGERGPPGNP----GL 610

Query: 934  HGQPGGGIRFEGPLLQQGVGMRFEGPHGQS-VAGLRFEGQHNQLGGNLRFEGPHGQPGVG 992
             G PG      GP+   G G    GP G+  + G+   G   Q G      GP G PG  
Sbjct: 611  PGLPGN----IGPMGPPGFGP--PGPVGEKGIQGVA--GNPGQPG----IPGPKGDPGQT 658

Query: 993  IRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRF 1052
            I   G             P +PG   R +G +G  G            G PGQP L P  
Sbjct: 659  ITQPGK------------PGLPGNPGR-DGDVGLPGD----------PGLPGQPGL-PGI 694

Query: 1053 DGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQR--FDGPQHQQASRFDIPLG 1110
             G  G+PG      PG PGP+ F G PG    P   G P R   +GP       F  P G
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPGIPG---PPGAPGTPGRIGLEGPPGPPG--FPGPKG 749

Query: 1111 LQGTRFDNHPSQRLESVSFNQTGPYND-----PPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
              G      P            GP  D     PPG        GL   + +       GP
Sbjct: 750  EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD------VGP 803

Query: 1166 NFN-GPHGP 1173
            N   GP GP
Sbjct: 804  NGQPGPMGP 812



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 124/379 (32%), Positives = 153/379 (40%), Gaps = 71/379 (18%)

Query: 780  IDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIG 839
            I GPP    L   G PG +GGGG     GP G+ G       +G PGP G     +G  G
Sbjct: 1135 ISGPPGNPGL--PGEPGPVGGGGHPGQPGPPGEKGKPGQ---DGIPGPAGQ----KGEPG 1185

Query: 840  QAGGGGFRFEGSPGLRFE-------GSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFE 892
            Q G G     G PGL  +       G PG     GP G+P G   F G +G P       
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP-GFHGFPGVQGPP------- 1237

Query: 893  GPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG----GGIRFE-GPL 947
            GP G P  G   + P+G P G     G  GP+G      GP G PG    GGI+ E G  
Sbjct: 1238 GPPGSP--GPALEGPKGNP-GPQGPPGRPGPTGFQ-GLPGPEGPPGLPGNGGIKGEKGNP 1293

Query: 948  LQQGV----GMRFE-GPHG-------QSVAGLRFEGQHNQLGGNLRFEGPHGQPG-VGIR 994
             Q G+    G++ + GP G         + G++ +     + G    +GP G PG  G  
Sbjct: 1294 GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1353

Query: 995  FEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGG----------PRFEGCHALRFD-GQP 1043
             E  L+   G     GPS  G  + I+G  G  G          P  +G   L    G P
Sbjct: 1354 GEPGLIGPPGPPGLPGPS--GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPP 1411

Query: 1044 GQPSL--LPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQ------VQPRFDGVPQRFD 1095
            G P    LP FDG  G+ G      PGQPG +  DGPPG          P    V   F 
Sbjct: 1412 GDPGRNGLPGFDGAGGRKGD--PGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFL 1469

Query: 1096 GPQHQQASRFDIPLGLQGT 1114
              +H Q +  D P   QGT
Sbjct: 1470 ITRHSQTT--DAPQCPQGT 1486



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 131/406 (32%), Positives = 158/406 (38%), Gaps = 64/406 (15%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P   G P    +   G PG  G  G     GP G  G    +  EGPPGP G    F GP
Sbjct: 695  PGSKGEPGIPGIGLPGPPGPKGFPG---IPGPPGAPGTPGRIGLEGPPGPPG----FPGP 747

Query: 838  IGQAGGGGFRFEGSPGL-RFEGS--PGGLR-FEGPGGQPVGGLRFEGHRGQPVGGLRFEG 893
             G+ G       G PGL  F+G+  P G R F GP G P G    +G  G P G +   G
Sbjct: 748  KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP-GRTGLDGLPG-PKGDV---G 802

Query: 894  PHGQPVGGLRFDNPRGQP-VGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGV 952
            P+GQP        P G P + G+  +G  GP G      GP GQPG      G   ++G 
Sbjct: 803  PNGQP-------GPMGPPGLPGIGVQGPPGPPG----IPGPIGQPG----LHGIPGEKG- 846

Query: 953  GMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGV-GIRFEGPLVQQGGGMRFEGP 1011
                 GP G  V G   E     + G     GP G PG+ G           G M   GP
Sbjct: 847  ---DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 1012 SVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPG 1071
              P G L I G    G P  +G   L+  GQPG P       G  G+PG      PG PG
Sbjct: 904  PGPPGPLGIPG--RSGVPGLKGDDGLQ--GQPGLPGPTGE-KGSKGEPG-----LPGPPG 953

Query: 1072 PQ--RFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSF 1129
            P      G  G++ +P   G+P    GP+  Q        GL G      P    +    
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGIP-GVSGPKGYQ--------GLPGD--PGQPGLSGQPGLP 1002

Query: 1130 NQTGPYNDP--PGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGP 1173
               GP  +P  PG        GL+    +  F  PQG    GP GP
Sbjct: 1003 GPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQG--VEGPPGP 1046



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 130/408 (31%), Positives = 161/408 (39%), Gaps = 84/408 (20%)

Query: 777  SPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVG----TPL 832
            +P + G P P      G  G  G  GP   +G  GQ G   P   +G PG  G     P 
Sbjct: 1141 NPGLPGEPGPV-----GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195

Query: 833  RFEGPIGQAGGGGF-RFEGSPGLRF-EGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLR 890
               G  GQ G GG     G+PGL   +G PG   F G  G P       G  G P  G  
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPP-------GPPGSP--GPA 1246

Query: 891  FEGPHGQPVGGLRFDNPRGQP--VGGLRFEGGHGPSGAAIRFDGPHGQPG-GGIRFEGPL 947
             EGP G P        P+G P   G   F+G  GP       +GP G PG GGI+ E   
Sbjct: 1247 LEGPKGNP-------GPQGPPGRPGPTGFQGLPGP-------EGPPGLPGNGGIKGE--- 1289

Query: 948  LQQGVGMRFEGPHGQ-SVAGL-RFEGQHNQLGGNLRFEGPHGQPGV-GIRFEGPLVQQGG 1004
                     +G  GQ  + GL   +G     G     +G  G+PG+ G++ +  L    G
Sbjct: 1290 ---------KGNPGQPGLPGLPGLKGDQGPPG----LQGNPGRPGLNGMKGDPGLPGVPG 1336

Query: 1005 GMRFEGPS-VPG-----GGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQ 1058
                +GPS VPG     G   + GP G  G       ++   G  G P  +P   GL G 
Sbjct: 1337 FPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPG-IPGQPGLKGL 1395

Query: 1059 PGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTR-FD 1117
            PGP  +   G PGP    G PG+   P FDG   R   P         +P G  GTR  D
Sbjct: 1396 PGP--QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP--------GLP-GQPGTRGLD 1444

Query: 1118 NHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
              P            GP   PPG   ++ + G    RH Q  D+PQ P
Sbjct: 1445 GPPGPD------GLQGP-PGPPGT--SSVAHGFLITRHSQTTDAPQCP 1483



 Score = 92.0 bits (227), Expect = 4e-18
 Identities = 132/438 (30%), Positives = 167/438 (38%), Gaps = 91/438 (20%)

Query: 792  DGSPGQMGGGGPLRFEGPQGQLGG-GCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEG 850
            +G PG  G  GP    GP+GQ G  G P    GPPGP G      GP G  G     F G
Sbjct: 56   EGHPGLPGFPGPEGPPGPRGQKGDDGIP----GPPGPKG----IRGPPGLPG-----FPG 102

Query: 851  SPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP--VGGLRFEGPHGQP-VGGLR---- 903
            +PGL   G PG     GP G P G    +G RG P   G    +GP G P + G++    
Sbjct: 103  TPGL--PGMPGHDGAPGPQGIP-GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPG 159

Query: 904  ------FDNPRGQP--VGGLRFEGGHGPSGAAIRFDGPHGQPG--------GGIRFEGPL 947
                     P+G P   G    +G  GP+G      GP G PG        G     GP 
Sbjct: 160  SIIMSSLPGPKGNPGYPGPPGIQGLPGPTG----IPGPIGPPGPPGLMGPPGPPGLPGP- 214

Query: 948  LQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPL--VQQGGG 1005
             +  +G+ F+GP G+               G    +GP G PG     + P+    Q G 
Sbjct: 215  -KGNMGLNFQGPKGEK--------------GEQGLQGPPGPPGQISEQKRPIDVEFQKGD 259

Query: 1006 MRFEGPSVPGGGLRIEGPLG-QGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPG-PRF 1063
                G   P G   I GP G  GG + E        G+PG+    P  DG +GQPG P  
Sbjct: 260  QGLPGDRGPPGPPGIRGPPGPPGGEKGEKGE----QGEPGKRG-KPGKDGENGQPGIPGL 314

Query: 1064 ERTPGQPGPQRFDGPPGQQVQPRFDG-----VPQRFDGPQHQQASRFDIPLGLQGTRFDN 1118
               PG PG    DG  GQ+      G     +P+   G    +     +P GL       
Sbjct: 315  PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLP-GL------- 366

Query: 1119 HPSQRLESVSFNQTGP--YNDPPGNAFNAP--SQGLQFQRHEQIFDSPQGPNFNGPHG-- 1172
             P ++ E       GP     PPG A   P    G   +R ++  + P G +  GP G  
Sbjct: 367  -PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD 425

Query: 1173 --PGNQSFSNPLNRASGH 1188
              PG      P   A  H
Sbjct: 426  GQPGAPGLPGPPGPAGPH 443



 Score = 87.8 bits (216), Expect = 7e-17
 Identities = 134/414 (32%), Positives = 155/414 (37%), Gaps = 103/414 (24%)

Query: 750  PLFDGPS-RPSVARDGPTKMIFEGP-------NKLSPRID----GPP-TPASLRFDGSPG 796
            P F GP   P  A  GP      GP         L P+ D    GPP  P     DG PG
Sbjct: 742  PGFPGPKGEPGFALPGPP-----GPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796

Query: 797  QMGGGGPLRFEGPQGQLGGGCP-LRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE----GS 851
              G  GP    GP G    G P +  +GPPGP G P    GPIGQ G  G   E    G 
Sbjct: 797  PKGDVGPNGQPGPMGP--PGLPGIGVQGPPGPPGIP----GPIGQPGLHGIPGEKGDPGP 850

Query: 852  PGLRFEGSPGGLRFEGPGGQP--------------VGGLRFEGHRGQ--------PVGGL 889
            PGL   G PG     G  G P               G   F G +G+        P G L
Sbjct: 851  PGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 890  RFEGPHGQPVGGLRFDNP-RGQP--------VGGLRFEGGHGPSGAA----IRFDGPHGQ 936
               G  G P  GL+ D+  +GQP         G     G  GP G      +   G  G+
Sbjct: 911  GIPGRSGVP--GLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGE 968

Query: 937  PG--GGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIR 994
            PG  G     GP   QG+     G  GQ   GL   GQ    G      GP G PG+  +
Sbjct: 969  PGLPGIPGVSGPKGYQGL----PGDPGQP--GL--SGQPGLPGP----PGPKGNPGLPGQ 1016

Query: 995  --FEGPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGG----PRFEGCHALRFD-GQPGQ 1045
                GP   +G  G M F GP        +EGP G  G    P   G    + D G PG 
Sbjct: 1017 PGLIGPPGLKGTIGDMGFPGPQ------GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 1046 PSL-LPRFDGLHGQPG-------PRFERTPGQPGPQRFDGPPGQQVQPRFDGVP 1091
             S+ LP   G  G+PG       P  + + G PG     G PG + QP   G P
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP 1124



 Score = 81.3 bits (199), Expect = 7e-15
 Identities = 147/513 (28%), Positives = 182/513 (35%), Gaps = 112/513 (21%)

Query: 750  PLFDGPSRPSVAR-----DG----PTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGG 800
            P F GP  P   R     DG    P      GP  L      P  P     DG+PG  G 
Sbjct: 62   PGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI 121

Query: 801  GGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP-----------LRFEGPIGQAGGGGFRFE 849
             G    +G +G  G       +GPPGP G P               GP G  G     + 
Sbjct: 122  PGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPG-----YP 176

Query: 850  GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP-------VGGLRFEGPHGQPVGGL 902
            G PG+  +G PG     GP G P G     G  G P         GL F+GP G+  G  
Sbjct: 177  GPPGI--QGLPGPTGIPGPIGPP-GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK-GEQ 232

Query: 903  RFDNPRGQP---------------VGGLRFEGGHGPSG-AAIRFDGPHGQPGGGIRFEGP 946
                P G P                G     G  GP G   IR  GP G PGG    +G 
Sbjct: 233  GLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR--GPPGPPGGEKGEKGE 290

Query: 947  LLQQGVGMR--FEGPHGQ-SVAGL----RFEGQHNQLG--GNLRFEGPHGQPGVGIRFEG 997
              + G   +   +G +GQ  + GL     + G+  + G  G     GP G PG+ I   G
Sbjct: 291  QGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPG 350

Query: 998  PLVQQGGGMRFEGPSVPG-----GGLRIEGPLGQGGPRFEGCHALRFDGQPGQPS----- 1047
              +  G       P +PG     G   I+GP G  GP   G   +   G PG P      
Sbjct: 351  TGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP--PGAAVMGPPGPPGFPGERGQK 408

Query: 1048 --------LLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQH 1099
                     +P   GL GQPG      PG PGP    GP G  + P  D + +   GP  
Sbjct: 409  GDEGPPGISIPGPPGLDGQPG-----APGLPGP---PGPAGPHIPPS-DEICE--PGPPG 457

Query: 1100 QQASRFDIPL-GLQGTRFDNHPSQRLESVSFNQTGPYNDP--PGNAFNAPSQGLQFQRHE 1156
               S  D  L G QG + D   +     +    +GP   P  PG      S G   Q+ E
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDT-CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516

Query: 1157 Q-------------IFDSPQGPNFNGPHG-PGN 1175
            +             I  +P  P F G  G PG+
Sbjct: 517  KGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD 549



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 39/125 (31%), Positives = 47/125 (37%), Gaps = 23/125 (18%)

Query: 1054 GLHGQPG----PRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPL 1109
            G+ G+ G    P  E  PG PG    +GPPG + Q   DG+P    GP   +  R   P 
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIP----GPPGPKGIRG--PP 95

Query: 1110 GLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIF-DSPQGPNFN 1168
            GL G  F   P            GP   P          G    + E+ F  SP  P   
Sbjct: 96   GLPG--FPGTPGLPGMPGHDGAPGPQGIP----------GCNGTKGERGFPGSPGFPGLQ 143

Query: 1169 GPHGP 1173
            GP GP
Sbjct: 144  GPPGP 148



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 5/64 (7%)

Query: 771  EGPNKLSPRIDGPPTPASLR----FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPG 826
            +GP  L P   GPP          FDG+ G+ G  G     G +G  G   P   +GPPG
Sbjct: 1399 QGPQGL-PGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1457

Query: 827  PVGT 830
            P GT
Sbjct: 1458 PPGT 1461


>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score =  102 bits (254), Expect = 3e-21
 Identities = 146/456 (32%), Positives = 181/456 (39%), Gaps = 105/456 (23%)

Query: 780  IDGPP-TPASLRFDGSPGQMGGGGPLRFE-----GPQGQLGGGCPLRFEGPPGPVGTPLR 833
            I GPP  P    F G+ G+ G  GP         G QG  G        G PGP+G    
Sbjct: 326  ITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEP 385

Query: 834  FE-GPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGP-GGQPVGGLRFEGHRGQ--PVG-- 887
             + GP G  G  G R  G PG  F G  G    EGP G Q + GL  +G +G   PVG  
Sbjct: 386  GQPGPRGPEGVPGER--GLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQ 443

Query: 888  ------GLRFEGPHG--QPVGGLRFDNPRGQPVGGLRFEGGH-GPSG----AAIRFDGPH 934
                  G+  +G  G   P+G      P GQ + G + E G  GP+G      I   GP 
Sbjct: 444  GPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPK 503

Query: 935  GQPGG-------GIRFE----GPLLQQGV-GMRF-EGPHGQSVAGLR-FEGQHNQLG--- 977
            G+PG        G+  E    G   + G+ G R  EGP G+   G +  EG+    G   
Sbjct: 504  GEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQG 563

Query: 978  --GNLRFEGPHGQPGV-------GIRFEGPLVQQGGGMRFEGPSVPG----GGLRIEGPL 1024
              G    EGP G+PG+       G    GP   +G      GP +PG     GL I GP 
Sbjct: 564  QRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDR---GGPGIPGFKGEPGLSIRGPK 620

Query: 1025 GQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQ--RFDGPPGQQ 1082
            G  GPR          G  G P L  + DG  G PGPR    PG PGP   R  G  G +
Sbjct: 621  GVQGPR----------GPVGAPGL--KGDGYPGVPGPR--GLPGPPGPMGLRGVGDTGAK 666

Query: 1083 VQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNA 1142
             +P   G P    GP   +       +G QG + D               GP   PPG  
Sbjct: 667  GEPGVRGPP----GPSGPRG------VGTQGPKGDTGQK--------GLPGP-PGPPGYG 707

Query: 1143 FNAPSQGLQFQRHEQIFDSPQG------PNFNGPHG 1172
                SQG++ ++  Q F  P+G      P   G HG
Sbjct: 708  ----SQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHG 739



 Score =  102 bits (253), Expect = 4e-21
 Identities = 130/414 (31%), Positives = 168/414 (40%), Gaps = 67/414 (16%)

Query: 793  GSPGQMGGGGPLRFEGPQGQLGGGCPLRFE------GPPGPVGTPLRFEGPIGQAGGGGF 846
            GSPG  G  GP   +G  G  G   P  F+      GPPGP G+P      IGQ G  G 
Sbjct: 310  GSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP--GAPGIGQQGIKGE 367

Query: 847  RFE----GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGL 902
            R +    G+PG    G PG     GP G P       G RG P  G  F GP G+     
Sbjct: 368  RGQEGRPGAPGPIGVGEPGQPGPRGPEGVP-------GERGLP--GEGFPGPKGEKGS-- 416

Query: 903  RFDNPRG-QPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIR----FEGPLLQQGVGMRFE 957
              + P G Q + GL  +G  G  G  +   GP G PG G +     +GP+   G     +
Sbjct: 417  --EGPTGPQGLQGLSIKGEKGDIG-PVGPQGPMGIPGIGSQGEQGIQGPIGPPGP----Q 469

Query: 958  GPHGQSVAGLRFE-GQHNQLGG----NLRFEGPHGQPG-VGIRFEGPLVQQGGGMRFEGP 1011
            GP GQ + G + E GQ    G      +  +GP G+PG +G+  +  +  + G    +G 
Sbjct: 470  GPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGE 529

Query: 1012 SVPGGGLRIEGPLGQGGPRFEGCHALR-FDGQPGQPSLLPRFDGLHGQP------GPRFE 1064
            +   G    EGP G+G P  +G    +   G  GQ   LP  +G  G+P      G    
Sbjct: 530  AGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRG-LPGPEGPKGEPGIMGPFGMPGT 588

Query: 1065 RTPGQPGPQRFDGPPGQQVQPRFDGVP-QRFDGPQHQQASRFDIPLGLQGTRFDNHPSQR 1123
              PG PGP+   G PG    P F G P     GP+  Q  R   P+G  G + D +P   
Sbjct: 589  SIPGPPGPKGDRGGPG---IPGFKGEPGLSIRGPKGVQGPRG--PVGAPGLKGDGYP--- 640

Query: 1124 LESVSFNQTGPYNDP-PGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQ 1176
                     GP   P P         G    + E     P GP  +GP G G Q
Sbjct: 641  ------GVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGP--SGPRGVGTQ 686



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 106/347 (30%), Positives = 127/347 (36%), Gaps = 84/347 (24%)

Query: 754  GPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQL 813
            GP+ P     GP  +  +GP      I  P  P     DG+ G+ G  G     GP+G  
Sbjct: 487  GPTGPR----GPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPP 542

Query: 814  GGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRF-------EGSPGLRFEGSPGGLRFE 866
            G       +G PGP G     EG  G  G  G R        +G PG+       G    
Sbjct: 543  G-------KGQPGPKGD----EGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP 591

Query: 867  GPGGQ--PVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVG--GLRFEGGHG 922
            GP G     GG    G +G+P  GL   GP G          PRG PVG  GL+ +G  G
Sbjct: 592  GPPGPKGDRGGPGIPGFKGEP--GLSIRGPKG-------VQGPRG-PVGAPGLKGDGYPG 641

Query: 923  PSGAAIRFDGPHGQPGGGIRFEGPLLQQGVG-------MRFEGPHGQSVAGLRFEGQHNQ 975
                     GP G PG      GP+  +GVG           GP G S  G R  G    
Sbjct: 642  -------VPGPRGLPGP----PGPMGLRGVGDTGAKGEPGVRGPPGPS--GPRGVGTQGP 688

Query: 976  LG--GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEG 1033
             G  G     GP G PG G +    +  + G   F GP         +G +G G P  +G
Sbjct: 689  KGDTGQKGLPGPPGPPGYGSQ---GIKGEQGPQGFPGP---------KGTMGHGLPGQKG 736

Query: 1034 CHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPG 1080
             H  R D             G  G  G   E  PG PG Q   GP G
Sbjct: 737  EHGERGD------------VGKKGDKGEIGE--PGSPGKQGLQGPKG 769



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 112/419 (26%), Positives = 151/419 (36%), Gaps = 119/419 (28%)

Query: 850  GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVG--------GLRFE--------- 892
            G PG    G+PG     GP G P    + E     P G        G R E         
Sbjct: 251  GPPGTH--GNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKGD 308

Query: 893  ----GPHGQ--PVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGG------G 940
                GP+G   P G      P G P G   F+G  G  G      GP+G PG       G
Sbjct: 309  KGSPGPYGPKGPRGIQGITGPPGDP-GPKGFQGNKGEPGP----PGPYGSPGAPGIGQQG 363

Query: 941  IRFE---------------------GPLLQQGV-------GMRFEGPHG----------Q 962
            I+ E                     GP   +GV       G  F GP G          Q
Sbjct: 364  IKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQ 423

Query: 963  SVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFE-------GPLVQQG----------GG 1005
             + GL  +G+   + G +  +GP G PG+G + E       GP   QG          G 
Sbjct: 424  GLQGLSIKGEKGDI-GPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGE 482

Query: 1006 MRFEGPSVPGG--GLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQ----- 1058
            +   GP+ P G  G+ ++GP G+ G            G PGQP  +P  DG  G+     
Sbjct: 483  VGQMGPTGPRGPVGIGVQGPKGEPGS----------IGLPGQPG-VPGEDGAAGKKGEAG 531

Query: 1059 -PGPRFERTP---GQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGT 1114
             PG R    P   GQPGP+  +G  G +      G+P   +GP+ +       P G+ GT
Sbjct: 532  LPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGP-EGPKGEPGIMG--PFGMPGT 588

Query: 1115 RFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGP 1173
                 P  + +       G +   PG +   P +G+Q  R        +G  + G  GP
Sbjct: 589  SIPGPPGPKGDRGGPGIPG-FKGEPGLSIRGP-KGVQGPRGPVGAPGLKGDGYPGVPGP 645



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 83/287 (28%), Positives = 109/287 (37%), Gaps = 69/287 (24%)

Query: 893  GPHGQPVGGLRFDN-PRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQG 951
            G HG P  G++ +  P+G P    + E G    G    + G  G+ G       P ++  
Sbjct: 254  GTHGNP--GIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG---ECGKPGIKGD 308

Query: 952  VGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGP 1011
             G    GP+G    G R         G     GP G PG    F+G   + G    +  P
Sbjct: 309  KGS--PGPYGPK--GPR---------GIQGITGPPGDPGPK-GFQGNKGEPGPPGPYGSP 354

Query: 1012 SVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPG 1071
              PG        +GQ G + E        GQ G+P          G PGP     PGQPG
Sbjct: 355  GAPG--------IGQQGIKGER-------GQEGRP----------GAPGPIGVGEPGQPG 389

Query: 1072 PQRFDGPPGQQVQPRFDGVP-QRFDGPQHQQASRFDI-PLGLQGTRFDNHPSQRLESVSF 1129
            P+  +G PG++      G+P + F GP+ ++ S     P GLQG       S + E    
Sbjct: 390  PRGPEGVPGER------GLPGEGFPGPKGEKGSEGPTGPQGLQGL------SIKGEKGDI 437

Query: 1130 NQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQ 1176
               GP    P       SQG      EQ    P GP   GP GP  Q
Sbjct: 438  GPVGPQG--PMGIPGIGSQG------EQGIQGPIGP--PGPQGPAGQ 474



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 43/127 (33%), Positives = 54/127 (42%), Gaps = 24/127 (18%)

Query: 746 AEDRPLFDGPSRPSVARDGPTKMIFEGPNKLSPR--IDGPPTPASLRFDGSPGQMGGGGP 803
           A+  P   GP  PS    GP  +  +GP   + +  + GPP P      GS G  G  GP
Sbjct: 665 AKGEPGVRGPPGPS----GPRGVGTQGPKGDTGQKGLPGPPGPPGY---GSQGIKGEQGP 717

Query: 804 LRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGL 863
             F GP+G +G G P    G  G  G      G +G+ G  G    G P     GSPG  
Sbjct: 718 QGFPGPKGTMGHGLP----GQKGEHGE----RGDVGKKGDKG--EIGEP-----GSPGKQ 762

Query: 864 RFEGPGG 870
             +GP G
Sbjct: 763 GLQGPKG 769


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  102 bits (253), Expect = 4e-21
 Identities = 159/504 (31%), Positives = 191/504 (37%), Gaps = 98/504 (19%)

Query: 753  DGPSRPSVAR-----DGPTKMIFEGPNKLSPRIDGPPTPASLR-FDGSPGQ--------- 797
            DGP+ P   R      GPT   F GP        GPP P       G PGQ         
Sbjct: 939  DGPAGPPGERGPNGPQGPTG--FPGPK-------GPPGPPGKDGLPGHPGQRGETGFQGK 989

Query: 798  MGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSP-GLRF 856
             G  GP    GPQG  G   P+   G PGP G P   +G  G AG  G + +  P GL  
Sbjct: 990  TGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGE-QGLPGLAGKEGTKGDPGPAGLPG 1048

Query: 857  EGSPGGLR-FEGPGG--QPVGGLRFEGHRGQ-----PVGGLRFEGPHGQ--PVGGLRFDN 906
            +  P GLR F G  G   PVG L  +G+ G      P G     GP G   P+G      
Sbjct: 1049 KDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPG 1108

Query: 907  PRGQ--PVGGLRFEGGHGPSGAAIR--FDGPHGQPG--------------------GGIR 942
            P+G   P G     G  GP G A R    GP G PG                    G   
Sbjct: 1109 PQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKG 1168

Query: 943  FEGPLLQQGV--GMRFEGPHGQ-SVAGLRFE-GQHNQLG--GNLRFEGPHGQPG----VG 992
             +G   +QG       +GP GQ   +G   E G   Q G  G    EGP G PG    VG
Sbjct: 1169 SKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVG 1228

Query: 993  IR-FEGPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGPR-----FEGCHALRFDGQPG 1044
            ++   GP  ++G  G +   GP  P G     G  G  GP+          A+   G+PG
Sbjct: 1229 LQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPG 1288

Query: 1045 QPSLLPRFDGLHGQPGPRFER-TPGQPGPQRFDGPPGQQVQPRFDGV-----PQRFDG-- 1096
            +    P   G  G PGP+ ER   G+ GP    GPPG +  P  DG      P  F G  
Sbjct: 1289 EAG-EPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDP 1347

Query: 1097 --PQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGP-----YNDPPGNAFNAPSQG 1149
              P     +  D P G +G   D  P Q        + GP        PPG A     QG
Sbjct: 1348 GPPGEPGPAGQDGPPGDKGD--DGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405

Query: 1150 LQFQRHEQIFDSPQGPNFNGPHGP 1173
             +  + E   + P  P   GP GP
Sbjct: 1406 EKGAKGEAGLEGP--PGKTGPIGP 1427



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 127/403 (31%), Positives = 157/403 (38%), Gaps = 90/403 (22%)

Query: 782  GPPTPASLR-FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQ 840
            GPP P  +   DG PG  G  GP    GP GQ G        GP G +G P   +GP+G+
Sbjct: 691  GPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGE-KGPLGK 749

Query: 841  AGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVG 900
             G       G PG   +G PG    EGP G+       +G +G P       GP G P+G
Sbjct: 750  PG-----LPGMPGA--DGPPGHPGKEGPPGE-------KGGQGPP-------GPQG-PIG 787

Query: 901  GLRFDNPRG----QPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGVGM 954
               +  PRG      + GL+   G         F G  G  G  G I   GP  + G   
Sbjct: 788  ---YPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGP-- 842

Query: 955  RFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVP 1014
              EGP G+                     GP+G P       GPL   G   +   P +P
Sbjct: 843  --EGPKGRG--------------------GPNGDP-------GPLGPPGEKGKLGVPGLP 873

Query: 1015 GGGLRIEGPLGQ-GGPRFEGCHALRFD-GQPGQPSLLPRFDGLHGQPGPRFERTP----G 1068
            G   R +GP G  G P F G +  +   G PG+P   PR  G  G  GPR ER P    G
Sbjct: 874  GYPGR-QGPKGSIGFPGFPGANGEKGGRGTPGKPG--PR--GQRGPTGPRGERGPRGITG 928

Query: 1069 QPGPQRFD------GPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQ 1122
            +PGP+         GPPG++  P     P  F GP+         P G  G     HP Q
Sbjct: 929  KPGPKGNSGGDGPAGPPGER-GPNGPQGPTGFPGPKGPPG-----PPGKDG--LPGHPGQ 980

Query: 1123 RLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
            R E+    +TGP   PPG        G      E+    P GP
Sbjct: 981  RGETGFQGKTGP-PGPPGVVGPQGPTGETGPMGERGHPGPPGP 1022



 Score = 95.5 bits (236), Expect = 4e-19
 Identities = 139/443 (31%), Positives = 174/443 (39%), Gaps = 87/443 (19%)

Query: 782  GPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQA 841
            GP  P  L   G PG +G  G    +G  G +G   P   +GPPGP G P    G  G+A
Sbjct: 559  GPAGPMGLT--GRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKP----GRRGRA 612

Query: 842  GGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGG 901
            G  G R  G PG    G  G   F+G  G P      +GHRG P       GP G P G 
Sbjct: 613  GSDGAR--GMPGQ--TGPKGDRGFDGLAGLP----GEKGHRGDP-------GPSGPP-GP 656

Query: 902  LRFDNPRGQ--PVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEG-PLLQQGVGMRF 956
               D  RG    VG     G  GP G  +   GP G PG  G    +G P  +  VG + 
Sbjct: 657  PGDDGERGDDGEVGPRGLPGEPGPRG-LLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQG 715

Query: 957  E-GPHGQS-----------VAGLRFEGQHNQLG-----GNLRFEGPHGQPGVGIRFEGPL 999
            E GP GQ               +   G+   LG     G    +GP G PG     EGP 
Sbjct: 716  EPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGK----EGPP 771

Query: 1000 VQQGGGMRFEGPSVPGGGLRIEGPLG-QGGPRFEGCHALRFD-GQPGQPSL-----LPRF 1052
             ++GG    +GP  P G +   GP G +G     G    + + G+ G P       +   
Sbjct: 772  GEKGG----QGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD 827

Query: 1053 DGLHGQPGPRFERTP----------GQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQA 1102
             G  G PGPR E  P          G PGP    GPPG++ +    G+P  + G Q  + 
Sbjct: 828  RGEIGPPGPRGEDGPEGPKGRGGPNGDPGPL---GPPGEKGKLGVPGLP-GYPGRQGPKG 883

Query: 1103 SRFDIP--------LGLQGTRFDNHP-SQRLESVSFNQTGP--YNDPPGNAFNAPSQGLQ 1151
            S    P         G +GT     P  QR  +    + GP      PG   N+   G  
Sbjct: 884  S-IGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPA 942

Query: 1152 FQRHEQIFDSPQGP-NFNGPHGP 1173
                E+  + PQGP  F GP GP
Sbjct: 943  GPPGERGPNGPQGPTGFPGPKGP 965



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 113/342 (33%), Positives = 141/342 (41%), Gaps = 91/342 (26%)

Query: 754  GPSRPSVA--RDGPTKMIFEGP-----NKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRF 806
            GP  PS A   DGP     +GP     N  +    G P  A     G PG  G GGP   
Sbjct: 1255 GPRGPSGAPGADGP-----QGPPGGIGNPGAVGEKGEPGEA-----GEPGLPGEGGPPGP 1304

Query: 807  EGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFE 866
            +G +G+ G   P    GPPGP G P   +GP G  G  G  F G PG    G PG    +
Sbjct: 1305 KGERGEKGESGPSGAAGPPGPKGPP-GDDGPKGSPGPVG--FPGDPGP--PGEPGPAGQD 1359

Query: 867  GPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGA 926
            GP G        +G  G+P G     GP G+P        P G P       G  GP G 
Sbjct: 1360 GPPGD-------KGDDGEP-GQTGSPGPTGEP-------GPSGPP-------GKRGPPGP 1397

Query: 927  AIRFDGPHGQPG-GGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGP 985
            A    GP G+ G  G + E  L         EGP G++              G +  +G 
Sbjct: 1398 A----GPEGRQGEKGAKGEAGL---------EGPPGKT--------------GPIGPQGA 1430

Query: 986  HGQPGV-GIR-FEGPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDG 1041
             G+PG  G+R   GP+ +QG  G    +GP  P G   + G  G  GP+          G
Sbjct: 1431 PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPK----------G 1480

Query: 1042 QPGQPSLLPRFDGLHGQPGPRFER-TPGQPGPQRFDGPPGQQ 1082
            + G P L+    GL G PG + E+   G PGPQ   GP G+Q
Sbjct: 1481 EKGHPGLI----GLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ 1518



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 138/439 (31%), Positives = 175/439 (39%), Gaps = 66/439 (15%)

Query: 772  GPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP 831
            GP      +  P  P     DG PG  G       EGP G+ GG      +GPPGP G P
Sbjct: 739  GPPGEKGPLGKPGLPGMPGADGPPGHPGK------EGPPGEKGG------QGPPGPQG-P 785

Query: 832  LRFEGPIGQAGGGGFR-FEGSPGLR----FEGSPGGLRFEGPGGQ--PVGGLRFEGHRGQ 884
            + + GP G  G  G R  +G+ G +    F G  G +  +G  G+  P G    +G  G 
Sbjct: 786  IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGP 845

Query: 885  PVGGLRFEGPHGQPVGGLRFDNPRGQ-PVGGL-RFEGGHGPSGAA--IRFDGPHGQPGG- 939
               G    GP+G P G L     +G+  V GL  + G  GP G+     F G +G+ GG 
Sbjct: 846  KGRG----GPNGDP-GPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGR 900

Query: 940  GIRFE-GPLLQQG-VGMRFE----------GPHGQS----VAGLRFEGQHNQLGGNLRFE 983
            G   + GP  Q+G  G R E          GP G S     AG   E   N   G   F 
Sbjct: 901  GTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFP 960

Query: 984  GPHGQPGVGIR--FEGPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRF 1039
            GP G PG   +    G   Q+G  G     GP  P G +  +GP G+ GP  E  H    
Sbjct: 961  GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGH---- 1016

Query: 1040 DGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRF---DGPPGQQVQPRFDGVPQRFDG 1096
             G PG P       GL G  G   E T G PGP      DGPPG +  P   G+P     
Sbjct: 1017 PGPPGPPG----EQGLPGLAGK--EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGA 1070

Query: 1097 PQHQQASRFDIPLGLQGTRFDNHPSQRLESVSF-NQTGPYNDPPGNAFNAPSQGLQFQRH 1155
               +       P G  G+  +  P+     +    + GP   PPG A    + G +  + 
Sbjct: 1071 LGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGP-QGPPGPAGEKGAPGEKGPQG 1129

Query: 1156 EQIFDSPQGP-NFNGPHGP 1173
                D  QGP    GP GP
Sbjct: 1130 PAGRDGLQGPVGLPGPAGP 1148



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 132/457 (28%), Positives = 170/457 (37%), Gaps = 119/457 (26%)

Query: 716  PRYEDSDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVARDGPT--------- 766
            P  ED DK  +  P  + +  D  +      +  P   GP  P + + GP+         
Sbjct: 1151 PPGEDGDKGEIGEPGQKGSKGDKGE------QGPPGPTGPQGP-IGQPGPSGADGEPGPR 1203

Query: 767  --KMIFEGPNKLSPR-IDGPPTPASLRF----------DGSPGQMGGGGPLRFEGPQGQL 813
              + +F       PR   GPP P  L+            G  GQMG  GP    GP G  
Sbjct: 1204 GQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAP 1263

Query: 814  GGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFE------- 866
            G   P   +GPPG +G P    G +G+ G  G    G PGL  EG P G + E       
Sbjct: 1264 GADGP---QGPPGGIGNP----GAVGEKGEPGEA--GEPGLPGEGGPPGPKGERGEKGES 1314

Query: 867  GPGGQ-----PVGGLRFEGHRGQP--VGGLRFEGPHGQPVGGLRFDNPRGQ--PVGGLRF 917
            GP G      P G    +G +G P  VG     GP G+P        P GQ  P G    
Sbjct: 1315 GPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEP-------GPAGQDGPPGDKGD 1367

Query: 918  EGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHG-QSVAGLRFEGQHNQL 976
            +G  G +G+     GP G+PG      GP  ++G      GP G Q   G + E      
Sbjct: 1368 DGEPGQTGSP----GPTGEPGPS----GPPGKRGPPGP-AGPEGRQGEKGAKGEAGLEGP 1418

Query: 977  GGNLRFEGPHGQPGV----GIR-FEGPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGP 1029
             G     GP G PG     G+R   GP+ +QG  G    +GP  P G   + G  G  GP
Sbjct: 1419 PGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGP 1478

Query: 1030 RFEGCHA--LRFDGQPGQ-----------------------------PSLLPRFDGLHGQ 1058
            + E  H   +   G PG+                             P   P   GL G 
Sbjct: 1479 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGP 1538

Query: 1059 PGPRFER----------TPGQPGPQRFDGPPGQQVQP 1085
            PGP+  +            G PGP    GPPG+ +QP
Sbjct: 1539 PGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQP 1575



 Score = 92.0 bits (227), Expect = 4e-18
 Identities = 143/461 (31%), Positives = 174/461 (37%), Gaps = 100/461 (21%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P   GPP PA  +  G+PG+ G  GP   +G QG +G        GP GPVG P   +G 
Sbjct: 1107 PGPQGPPGPAGEK--GAPGEKGPQGPAGRDGLQGPVG------LPGPAGPVGPPGE-DGD 1157

Query: 838  IGQAGGGGFRFEGSPGLRFE-GSPGGLRFEGPGGQP--VGGLRFEGHRGQP--------V 886
             G+ G  G +  GS G + E G PG    +GP GQP   G     G RGQ          
Sbjct: 1158 KGEIGEPGQK--GSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDE 1215

Query: 887  GGLRFEGPHGQPVGGLRFDNPRGQP-----VGGLRFEGGHGPSG--AAIRFDGPHGQPGG 939
            G   F GP G PVG      P G+      VG +   G  GP G   A   DGP G PGG
Sbjct: 1216 GPRGFPGPPG-PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGG 1274

Query: 940  GIRFEGPLLQQGV-------GMRFEG-PHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGV 991
             I   G + ++G        G+  EG P G    G R E   +   G     GP G PG 
Sbjct: 1275 -IGNPGAVGEKGEPGEAGEPGLPGEGGPPGPK--GERGEKGESGPSGAAGPPGPKGPPGD 1331

Query: 992  GIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQ------ 1045
                +GP    G  + F G   P G     GP GQ GP  +       DG+PGQ      
Sbjct: 1332 ----DGPKGSPGP-VGFPGDPGPPGE---PGPAGQDGPPGDKGD----DGEPGQTGSPGP 1379

Query: 1046 -----PSLLPRFDGLHGQPGPRFER-------------------------TPGQPGPQRF 1075
                 PS  P   G  G  GP   +                          PG+PGP   
Sbjct: 1380 TGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGL 1439

Query: 1076 DGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHP-SQRLESVSFNQTGP 1134
             G PG   +    G P   DGP          P GL G + D+ P  ++         GP
Sbjct: 1440 RGIPGPVGEQGLPGSPGP-DGPPGPMG-----PPGLPGLKGDSGPKGEKGHPGLIGLIGP 1493

Query: 1135 YND--PPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGP 1173
              +    G+      QG    + EQ    P GP   GP GP
Sbjct: 1494 PGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGP--IGPPGP 1532



 Score = 74.3 bits (181), Expect = 8e-13
 Identities = 117/373 (31%), Positives = 135/373 (36%), Gaps = 80/373 (21%)

Query: 750  PLFDGPSRPSVARDG-PTKM--IFEG--------PNKLSPRIDGPPTPASLRFDGSPGQM 798
            P +D  S PS    G P     I+EG          K  P I  P     +  +G PG  
Sbjct: 419  PYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEP----GMLIEGPPGPE 474

Query: 799  GGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAG-GGGFRFEGSPG--LR 855
            G  G     GP G +         GP G VG P    GP G+ G  G     G PG  L 
Sbjct: 475  GPAG---LPGPPGTM---------GPTGQVGDPGE-RGPPGRPGLPGADGLPGPPGTMLM 521

Query: 856  FEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQP-VGG 914
                 GG    G  G  V     +         L   GP G P+G      P G P  GG
Sbjct: 522  LPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAG-PMGLTGRPGPVGPPGSGG 580

Query: 915  LRFEGGH-GPSG--AAIRFDGPHGQPG--GGIRFEGPLLQQGVGMRFEGPHG----QSVA 965
            L+ E G  GP G        GP G+PG  G    +G     G      GP G      +A
Sbjct: 581  LKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQ----TGPKGDRGFDGLA 636

Query: 966  GLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLG 1025
            GL  E  H    G+    GP G PG             G    +G   P G     GP G
Sbjct: 637  GLPGEKGHR---GDPGPSGPPGPPG-----------DDGERGDDGEVGPRGLPGEPGPRG 682

Query: 1026 QGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQP 1085
              GP+          G PG P   P   G+ GQPGP+     G  GPQ   GPPGQQ  P
Sbjct: 683  LLGPK----------GPPGPPG-PPGVTGMDGQPGPK-----GNVGPQGEPGPPGQQGNP 726

Query: 1086 RFDGVPQRFDGPQ 1098
               G+P    GPQ
Sbjct: 727  GAQGLP----GPQ 735



 Score = 36.2 bits (82), Expect = 0.25
 Identities = 22/51 (43%), Positives = 24/51 (47%), Gaps = 2/51 (3%)

Query: 782  GPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPL 832
            GPP P  L   G PG  G  G     GP+G+ G   P    GPPG V  PL
Sbjct: 1528 GPPGPPGL--PGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPL 1576


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  101 bits (252), Expect = 5e-21
 Identities = 143/453 (31%), Positives = 178/453 (39%), Gaps = 70/453 (15%)

Query: 754  GPSRPSVARDGPTKMIFEGP--NKLSPRIDGPP----TPASLRFDGSPGQMGGGGPLRFE 807
            GP  P  AR  P      G   ++  P +DG       P      GSPG+ G  GP+   
Sbjct: 267  GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 326

Query: 808  GPQGQLGGGCPLRF------EGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPG 861
            G  G+ G   P         +G PGP G P    GP+G AGG G  F G+PG + E  P 
Sbjct: 327  GLPGERGRTGPAGAAGARGNDGQPGPAGPP----GPVGPAGGPG--FPGAPGAKGEAGPT 380

Query: 862  GLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGH 921
            G R  GP G        +G RG+P       G  G P       NP    + G +   G 
Sbjct: 381  GAR--GPEGA-------QGPRGEP-------GTPGSPGPAGASGNPGTDGIPGAKGSAGA 424

Query: 922  GPSGAAIRFDGPHGQPG--GGIRFEGPLLQQG----VGMRFE-GPHGQ-SVAGLRFEGQH 973
                 A  F GP G PG  G     GP  Q G     G + E GP G+   AG   +G  
Sbjct: 425  PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP--QGAP 482

Query: 974  NQLGGNLRFEGPHGQPGVGIRFEGPLVQQG--GGMRF---EGPSVPGGGLRIEGPLGQGG 1028
               G   +  G  G+PG G+   GP  ++G  G   F   +G + P G     GP G  G
Sbjct: 483  GPAGEEGK-RGARGEPG-GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG 540

Query: 1029 PRFEGCHALRFDGQPGQPSLLPRFDGLHGQP---GPRFERTP-GQPGPQRFDGPPGQQVQ 1084
            P+     A    G+PG+P  LP   GL G+P   GP+ +  P G PG     GPPG Q  
Sbjct: 541  PK----GANGDPGRPGEPG-LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGA 595

Query: 1085 PRFDGVPQRFDGPQHQQASRFDIPLGLQGTR-FDNHPSQRLESVSFNQTGPYNDPPGNAF 1143
                GV   F GP+           G  G +     P  R       +TG    PPG A 
Sbjct: 596  RGQPGV-MGFPGPKGANGEP-----GKAGEKGLPGAPGLRGLPGKDGETGAAG-PPGPAG 648

Query: 1144 NAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQ 1176
             A  +G Q       F    GP   GP G G +
Sbjct: 649  PAGERGEQGAPGPSGFQGLPGP--PGPPGEGGK 679



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 132/405 (32%), Positives = 153/405 (37%), Gaps = 76/405 (18%)

Query: 777  SPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEG 836
            +P   GPP P+    DG  G  G  GP    G  G  G   P   +G PG  G P   EG
Sbjct: 913  NPGPPGPPGPSGK--DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDG-PSGAEG 969

Query: 837  PIGQAGGGGFR-FEGSPGLRFE-GSPGGLRFEGPGGQP--VGGLRFEGHRGQP--VGGLR 890
            P G  G  G R   G PG R E G PG     GP G+P   G     G RG P  VG   
Sbjct: 970  PPGPQGLAGQRGIVGLPGQRGERGFPG---LPGPSGEPGKQGAPGASGDRGPPGPVGPPG 1026

Query: 891  FEGPHGQP--VGGLRFDNPRGQPVGGLRFEGGHGPSGA--AIRFDGPHGQPG-------- 938
              GP G+P   G    D P G+  G    +G  G +GA  A    GP G PG        
Sbjct: 1027 LTGPAGEPGREGSPGADGPPGRD-GAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085

Query: 939  ---GGIRFEGPLLQQG-VGMR-FEGPHG-QSVAGLRFEGQHNQLGGNLRFEGPHGQPGVG 992
               G    +GP+   G  G R  +GP G +   G   E     L G+  F G  G PG  
Sbjct: 1086 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGP- 1144

Query: 993  IRFEGPLVQQGG-------GMRFE----GPSVPGGGLRIEGPLGQGGPRFEGCHALRFDG 1041
                GP   QG        G R      GPS   G   I GP+G  GPR           
Sbjct: 1145 ---PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR----------- 1190

Query: 1042 QPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQV-QPRFDGVPQRFDGPQHQ 1100
                        G  G+ GP     PG PGP    GPPG  +    F G+  R  GP   
Sbjct: 1191 ------------GRSGETGP--AGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPL 1236

Query: 1101 QASRFDIPLGLQGTR-FDNHPSQRLESVSFNQTGPYNDPPGNAFN 1144
            Q  R D   G  G R  D      L+S++ NQ      P G+  N
Sbjct: 1237 QYMRADQAAG--GLRQHDAEVDATLKSLN-NQIESIRSPEGSRKN 1278



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 146/459 (31%), Positives = 165/459 (35%), Gaps = 104/459 (22%)

Query: 750  PLFDGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGP 809
            P  DGP   S    GP      GP    P   GPP        G PG+ G  G    +G 
Sbjct: 725  PGTDGPKGAS----GPA-----GP----PGAQGPPG-----LQGMPGERGAAGIAGPKGD 766

Query: 810  QGQLG-----------GGCPLRFE-GPPGPVGT--PLRFEGPIGQAGGGGFRFEGSPGLR 855
            +G +G           GG  L    GPPGP G        GP G AG  G R  G+PG R
Sbjct: 767  RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR--GAPGER 824

Query: 856  FE-GSPGGLRFEGP---GGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQP 911
             E G PG   F GP    GQP G    +G  GQ  G     GP G P G      P G  
Sbjct: 825  GETGPPGPAGFAGPPGADGQP-GAKGEQGEAGQK-GDAGAPGPQG-PSGAPGPQGPTG-V 880

Query: 912  VGGLRFEGGHGPSGAAIRFDGPHGQ--PGGGIRFEGPLLQQGVGMRFEGPHGQS----VA 965
             G     G  GP GA   F G  G+  P G     GP           GP G S      
Sbjct: 881  TGPKGARGAQGPPGAT-GFPGAAGRVGPPGSNGNPGP----------PGPPGPSGKDGPK 929

Query: 966  GLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLG 1025
            G R +       G    +GP G PG     E       G    EGP  P G     G +G
Sbjct: 930  GARGDSGPPGRAGEPGLQGPAGPPG-----EKGEPGDDGPSGAEGPPGPQGLAGQRGIVG 984

Query: 1026 QGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFER-TPGQPGPQRFDGP---PGQ 1081
              G R E      F G PG PS  P   G  G PG   +R  PG  GP    GP   PG+
Sbjct: 985  LPGQRGE----RGFPGLPG-PSGEP---GKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 1036

Query: 1082 QVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGN 1141
            +  P  DG P R            D   G++G         R E+ +    G    PPG+
Sbjct: 1037 EGSPGADGPPGR------------DGAAGVKG--------DRGETGAVGAPGA-PGPPGS 1075

Query: 1142 AFNAPSQGLQFQRHEQIFDSPQGPN-------FNGPHGP 1173
               A   G Q  R E     P GP+         GP GP
Sbjct: 1076 PGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1114



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 137/432 (31%), Positives = 161/432 (37%), Gaps = 99/432 (22%)

Query: 782  GPPTPASLRFD----GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            GPP PA    +    G PG  G  G     G +G+ G   P  F GPPG  G P   +G 
Sbjct: 792  GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP-GAKGE 850

Query: 838  IGQAGGGGFRFEGSPGLR----FEGSPGGLRFEGPGGQ-----PVGGLRFEGHRGQ--PV 886
             G+AG  G    G+PG +      G  G     GP G      P G   F G  G+  P 
Sbjct: 851  QGEAGQKG--DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 908

Query: 887  GGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIR--FDGPHGQPG--GGIR 942
            G     GP G P G    D P+G         G  GP G A      GP G PG  G   
Sbjct: 909  GSNGNPGPPGPP-GPSGKDGPKGA-------RGDSGPPGRAGEPGLQGPAGPPGEKGEPG 960

Query: 943  FEGPLLQQGVGMRFEGPHG-QSVAGLR-FEGQHNQLG--GNLRFEGPHGQPGVGIRFEGP 998
             +GP          EGP G Q +AG R   G   Q G  G     GP G+PG        
Sbjct: 961  DDGP-------SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG-------- 1005

Query: 999  LVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLH 1056
              +QG  G     GP  P G   + GP G+  P  EG      DG PG+       DG  
Sbjct: 1006 --KQGAPGASGDRGPPGPVGPPGLTGPAGE--PGREGSPGA--DGPPGR-------DGAA 1052

Query: 1057 GQPGPRFER----TPGQPGPQRFDGPPGQ--QVQPRFDGVPQRFDGPQHQQASRFDIPLG 1110
            G  G R E      PG PGP    GP G   +   R +   Q   GP     +R     G
Sbjct: 1053 GVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR-----G 1107

Query: 1111 LQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGP 1170
            +QG +                 GP  D  G A     +GL+  R    F   QG    GP
Sbjct: 1108 IQGPQ-----------------GPRGD-KGEAGEPGERGLKGHRG---FTGLQG--LPGP 1144

Query: 1171 HGP-GNQSFSNP 1181
             GP G+Q  S P
Sbjct: 1145 PGPSGDQGASGP 1156



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 118/380 (31%), Positives = 143/380 (37%), Gaps = 78/380 (20%)

Query: 769  IFEGP-NKLSPRIDGPPTPASLR----FDGSPGQMGG---GGPLRFEGPQGQLG------ 814
            + +GP   + PR  GPP PA       F G+PG+ G     GP+   GP G  G      
Sbjct: 198  VMQGPMGPMGPR--GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDG 255

Query: 815  -GGCPLRF-----EGPPGPVGTP--------------LRFEGPIGQAGGGGFRFE-GSPG 853
              G P +       GP G  G P                 +G  G+AG  G + E GSPG
Sbjct: 256  EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG 315

Query: 854  LRFEGSPGGLRFEGPGGQ-----PVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPR 908
                GSPG +   G  G+     P G     G+ GQP G     GP G P GG  F    
Sbjct: 316  --ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQP-GPAGPPGPVG-PAGGPGFPGAP 371

Query: 909  GQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLR 968
            G   G     G  GP GA     GP G+PG      GP    G       P    + G +
Sbjct: 372  GAK-GEAGPTGARGPEGA----QGPRGEPGTP-GSPGPAGASG------NPGTDGIPGAK 419

Query: 969  FEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG-----GGMRFEGPSVPGGGLRIEGP 1023
                   + G   F GP G PG      GPL  +G     G   F+G   P G     GP
Sbjct: 420  GSAGAPGIAGAPGFPGPRGPPGPQ-GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 478

Query: 1024 LGQGGPR-FEGCHALRFD-------GQPGQPSL-----LPRFDGLHGQPGPRFERTP-GQ 1069
             G  GP   EG    R +       G PG+         P  DGL G  G   ER P G 
Sbjct: 479  QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 538

Query: 1070 PGPQRFDGPPGQQVQPRFDG 1089
             GP+  +G PG+  +P   G
Sbjct: 539  AGPKGANGDPGRPGEPGLPG 558



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 144/450 (32%), Positives = 168/450 (37%), Gaps = 92/450 (20%)

Query: 772  GPNKLSPRIDGPPTPASLRFD-GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGT 830
            GP K  P   GP      R D G  G+ G  GP   +G  G  G   P    GPPGP G 
Sbjct: 117  GP-KGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGL 175

Query: 831  -----------------------------PLRFEGPIGQAGGGGFR-FEGSPGLRFE-GS 859
                                         P+   GP G AG  G + F+G+PG   E G 
Sbjct: 176  GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGV 235

Query: 860  PGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQP-VGGLR-- 916
             G +   GP G P G    +G  G+P G     GP G P G   F    G P V G R  
Sbjct: 236  SGPMGPRGPPGPP-GKPGDDGEAGKP-GKAGERGPPG-PQGARGFPGTPGLPGVKGHRGY 292

Query: 917  --FEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGV-GMRFE-GPHGQSVAGLRFEGQ 972
               +G  G +GA     G  G PG      GP+  +G+ G R   GP G   AG R    
Sbjct: 293  PGLDGAKGEAGAP-GVKGESGSPGEN-GSPGPMGPRGLPGERGRTGPAG--AAGAR---- 344

Query: 973  HNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPG--GGLRIEGPLGQGGPR 1030
                 GN    GP G P       GP+   G      GP  PG  G     GP G  GP 
Sbjct: 345  -----GNDGQPGPAGPP-------GPVGPAG------GPGFPGAPGAKGEAGPTGARGP- 385

Query: 1031 FEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGV 1090
             EG    R  G+PG P   P   G  G PG     T G PG +   G PG    P F G 
Sbjct: 386  -EGAQGPR--GEPGTPG-SPGPAGASGNPG-----TDGIPGAKGSAGAPGIAGAPGFPG- 435

Query: 1091 PQRFDGPQHQQASRFDIPLGLQG-TRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQG 1149
            P+   GPQ         PLG +G T        + E     + GP   P G    A  +G
Sbjct: 436  PRGPPGPQGATG-----PLGPKGQTGEPGIAGFKGEQGPKGEPGPAG-PQGAPGPAGEEG 489

Query: 1150 LQFQRHEQIFDSPQGPNFNGPHG-PGNQSF 1178
             +  R E     P GP   G  G PGN+ F
Sbjct: 490  KRGARGEPGGVGPIGP--PGERGAPGNRGF 517



 Score = 39.7 bits (91), Expect = 0.023
 Identities = 48/164 (29%), Positives = 57/164 (34%), Gaps = 35/164 (21%)

Query: 1025 GQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPR---FERTP----------GQPG 1071
            GQ GP+          GQ G+P  +    G  G PGP+    E+ P          G PG
Sbjct: 98   GQPGPK----------GQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPG 147

Query: 1072 PQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQ 1131
            P+  DG PG    P   G P    GP        +    + G  FD         V    
Sbjct: 148  PRGRDGEPGTPGNPGPPGPP----GPPGPPGLGGNFAAQMAG-GFDEKAGGAQLGVMQGP 202

Query: 1132 TGPY--NDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGP 1173
             GP     PPG A     QG Q    E     P  P  +GP GP
Sbjct: 203  MGPMGPRGPPGPAGAPGPQGFQGNPGE-----PGEPGVSGPMGP 241



 Score = 39.3 bits (90), Expect = 0.030
 Identities = 52/162 (32%), Positives = 68/162 (41%), Gaps = 30/162 (18%)

Query: 713  LKRPRYEDSDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVARDGPTKMIFEG 772
            ++ P+    DK     P  R  GL  ++  T L +  P   GPS    A  GP      G
Sbjct: 1108 IQGPQGPRGDKGEAGEPGER--GLKGHRGFTGL-QGLPGPPGPSGDQGA-SGPA-----G 1158

Query: 773  PNKLSPRIDGPPTPASLR----FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPV 828
            P+   PR  GPP P         +G PG +G  GP    G  G+ G   P    GPPGP 
Sbjct: 1159 PS--GPR--GPPGPVGPSGKDGANGIPGPIGPPGP---RGRSGETGPAGPPGNPGPPGPP 1211

Query: 829  GTPLRFEGP---IGQAGGGGFRFEGSPGLRF---EGSPGGLR 864
            G P    GP   +    G G R +G   L++   + + GGLR
Sbjct: 1212 GPP----GPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLR 1249


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  101 bits (252), Expect = 5e-21
 Identities = 143/453 (31%), Positives = 178/453 (39%), Gaps = 70/453 (15%)

Query: 754  GPSRPSVARDGPTKMIFEGP--NKLSPRIDGPP----TPASLRFDGSPGQMGGGGPLRFE 807
            GP  P  AR  P      G   ++  P +DG       P      GSPG+ G  GP+   
Sbjct: 198  GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 257

Query: 808  GPQGQLGGGCPLRF------EGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPG 861
            G  G+ G   P         +G PGP G P    GP+G AGG G  F G+PG + E  P 
Sbjct: 258  GLPGERGRTGPAGAAGARGNDGQPGPAGPP----GPVGPAGGPG--FPGAPGAKGEAGPT 311

Query: 862  GLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGH 921
            G R  GP G        +G RG+P       G  G P       NP    + G +   G 
Sbjct: 312  GAR--GPEGA-------QGPRGEP-------GTPGSPGPAGASGNPGTDGIPGAKGSAGA 355

Query: 922  GPSGAAIRFDGPHGQPG--GGIRFEGPLLQQG----VGMRFE-GPHGQ-SVAGLRFEGQH 973
                 A  F GP G PG  G     GP  Q G     G + E GP G+   AG   +G  
Sbjct: 356  PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP--QGAP 413

Query: 974  NQLGGNLRFEGPHGQPGVGIRFEGPLVQQG--GGMRF---EGPSVPGGGLRIEGPLGQGG 1028
               G   +  G  G+PG G+   GP  ++G  G   F   +G + P G     GP G  G
Sbjct: 414  GPAGEEGK-RGARGEPG-GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG 471

Query: 1029 PRFEGCHALRFDGQPGQPSLLPRFDGLHGQP---GPRFERTP-GQPGPQRFDGPPGQQVQ 1084
            P+     A    G+PG+P  LP   GL G+P   GP+ +  P G PG     GPPG Q  
Sbjct: 472  PK----GANGDPGRPGEPG-LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGA 526

Query: 1085 PRFDGVPQRFDGPQHQQASRFDIPLGLQGTR-FDNHPSQRLESVSFNQTGPYNDPPGNAF 1143
                GV   F GP+           G  G +     P  R       +TG    PPG A 
Sbjct: 527  RGQPGV-MGFPGPKGANGEP-----GKAGEKGLPGAPGLRGLPGKDGETGAAG-PPGPAG 579

Query: 1144 NAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQ 1176
             A  +G Q       F    GP   GP G G +
Sbjct: 580  PAGERGEQGAPGPSGFQGLPGP--PGPPGEGGK 610



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 132/405 (32%), Positives = 153/405 (37%), Gaps = 76/405 (18%)

Query: 777  SPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEG 836
            +P   GPP P+    DG  G  G  GP    G  G  G   P   +G PG  G P   EG
Sbjct: 844  NPGPPGPPGPSGK--DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDG-PSGAEG 900

Query: 837  PIGQAGGGGFR-FEGSPGLRFE-GSPGGLRFEGPGGQP--VGGLRFEGHRGQP--VGGLR 890
            P G  G  G R   G PG R E G PG     GP G+P   G     G RG P  VG   
Sbjct: 901  PPGPQGLAGQRGIVGLPGQRGERGFPG---LPGPSGEPGKQGAPGASGDRGPPGPVGPPG 957

Query: 891  FEGPHGQP--VGGLRFDNPRGQPVGGLRFEGGHGPSGA--AIRFDGPHGQPG-------- 938
              GP G+P   G    D P G+  G    +G  G +GA  A    GP G PG        
Sbjct: 958  LTGPAGEPGREGSPGADGPPGRD-GAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1016

Query: 939  ---GGIRFEGPLLQQG-VGMR-FEGPHG-QSVAGLRFEGQHNQLGGNLRFEGPHGQPGVG 992
               G    +GP+   G  G R  +GP G +   G   E     L G+  F G  G PG  
Sbjct: 1017 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGP- 1075

Query: 993  IRFEGPLVQQGG-------GMRFE----GPSVPGGGLRIEGPLGQGGPRFEGCHALRFDG 1041
                GP   QG        G R      GPS   G   I GP+G  GPR           
Sbjct: 1076 ---PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPR----------- 1121

Query: 1042 QPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQV-QPRFDGVPQRFDGPQHQ 1100
                        G  G+ GP     PG PGP    GPPG  +    F G+  R  GP   
Sbjct: 1122 ------------GRSGETGP--AGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPL 1167

Query: 1101 QASRFDIPLGLQGTR-FDNHPSQRLESVSFNQTGPYNDPPGNAFN 1144
            Q  R D   G  G R  D      L+S++ NQ      P G+  N
Sbjct: 1168 QYMRADQAAG--GLRQHDAEVDATLKSLN-NQIESIRSPEGSRKN 1209



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 146/459 (31%), Positives = 165/459 (35%), Gaps = 104/459 (22%)

Query: 750  PLFDGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGP 809
            P  DGP   S    GP      GP    P   GPP        G PG+ G  G    +G 
Sbjct: 656  PGTDGPKGAS----GPA-----GP----PGAQGPPG-----LQGMPGERGAAGIAGPKGD 697

Query: 810  QGQLG-----------GGCPLRFE-GPPGPVGT--PLRFEGPIGQAGGGGFRFEGSPGLR 855
            +G +G           GG  L    GPPGP G        GP G AG  G R  G+PG R
Sbjct: 698  RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR--GAPGER 755

Query: 856  FE-GSPGGLRFEGP---GGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQP 911
             E G PG   F GP    GQP G    +G  GQ  G     GP G P G      P G  
Sbjct: 756  GETGPPGPAGFAGPPGADGQP-GAKGEQGEAGQK-GDAGAPGPQG-PSGAPGPQGPTG-V 811

Query: 912  VGGLRFEGGHGPSGAAIRFDGPHGQ--PGGGIRFEGPLLQQGVGMRFEGPHGQS----VA 965
             G     G  GP GA   F G  G+  P G     GP           GP G S      
Sbjct: 812  TGPKGARGAQGPPGAT-GFPGAAGRVGPPGSNGNPGP----------PGPPGPSGKDGPK 860

Query: 966  GLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLG 1025
            G R +       G    +GP G PG     E       G    EGP  P G     G +G
Sbjct: 861  GARGDSGPPGRAGEPGLQGPAGPPG-----EKGEPGDDGPSGAEGPPGPQGLAGQRGIVG 915

Query: 1026 QGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFER-TPGQPGPQRFDGP---PGQ 1081
              G R E      F G PG PS  P   G  G PG   +R  PG  GP    GP   PG+
Sbjct: 916  LPGQRGE----RGFPGLPG-PSGEP---GKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 967

Query: 1082 QVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGN 1141
            +  P  DG P R            D   G++G         R E+ +    G    PPG+
Sbjct: 968  EGSPGADGPPGR------------DGAAGVKG--------DRGETGAVGAPGA-PGPPGS 1006

Query: 1142 AFNAPSQGLQFQRHEQIFDSPQGPN-------FNGPHGP 1173
               A   G Q  R E     P GP+         GP GP
Sbjct: 1007 PGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1045



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 137/432 (31%), Positives = 161/432 (37%), Gaps = 99/432 (22%)

Query: 782  GPPTPASLRFD----GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            GPP PA    +    G PG  G  G     G +G+ G   P  F GPPG  G P   +G 
Sbjct: 723  GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP-GAKGE 781

Query: 838  IGQAGGGGFRFEGSPGLR----FEGSPGGLRFEGPGGQ-----PVGGLRFEGHRGQ--PV 886
             G+AG  G    G+PG +      G  G     GP G      P G   F G  G+  P 
Sbjct: 782  QGEAGQKG--DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 839

Query: 887  GGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIR--FDGPHGQPG--GGIR 942
            G     GP G P G    D P+G         G  GP G A      GP G PG  G   
Sbjct: 840  GSNGNPGPPGPP-GPSGKDGPKGA-------RGDSGPPGRAGEPGLQGPAGPPGEKGEPG 891

Query: 943  FEGPLLQQGVGMRFEGPHG-QSVAGLR-FEGQHNQLG--GNLRFEGPHGQPGVGIRFEGP 998
             +GP          EGP G Q +AG R   G   Q G  G     GP G+PG        
Sbjct: 892  DDGP-------SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG-------- 936

Query: 999  LVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLH 1056
              +QG  G     GP  P G   + GP G+  P  EG      DG PG+       DG  
Sbjct: 937  --KQGAPGASGDRGPPGPVGPPGLTGPAGE--PGREGSPGA--DGPPGR-------DGAA 983

Query: 1057 GQPGPRFER----TPGQPGPQRFDGPPGQ--QVQPRFDGVPQRFDGPQHQQASRFDIPLG 1110
            G  G R E      PG PGP    GP G   +   R +   Q   GP     +R     G
Sbjct: 984  GVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR-----G 1038

Query: 1111 LQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGP 1170
            +QG +                 GP  D  G A     +GL+  R    F   QG    GP
Sbjct: 1039 IQGPQ-----------------GPRGD-KGEAGEPGERGLKGHRG---FTGLQG--LPGP 1075

Query: 1171 HGP-GNQSFSNP 1181
             GP G+Q  S P
Sbjct: 1076 PGPSGDQGASGP 1087



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 118/380 (31%), Positives = 143/380 (37%), Gaps = 78/380 (20%)

Query: 769  IFEGP-NKLSPRIDGPPTPASLR----FDGSPGQMGG---GGPLRFEGPQGQLG------ 814
            + +GP   + PR  GPP PA       F G+PG+ G     GP+   GP G  G      
Sbjct: 129  VMQGPMGPMGPR--GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDG 186

Query: 815  -GGCPLRF-----EGPPGPVGTP--------------LRFEGPIGQAGGGGFRFE-GSPG 853
              G P +       GP G  G P                 +G  G+AG  G + E GSPG
Sbjct: 187  EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG 246

Query: 854  LRFEGSPGGLRFEGPGGQ-----PVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPR 908
                GSPG +   G  G+     P G     G+ GQP G     GP G P GG  F    
Sbjct: 247  --ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQP-GPAGPPGPVG-PAGGPGFPGAP 302

Query: 909  GQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLR 968
            G   G     G  GP GA     GP G+PG      GP    G       P    + G +
Sbjct: 303  GAK-GEAGPTGARGPEGA----QGPRGEPGTP-GSPGPAGASG------NPGTDGIPGAK 350

Query: 969  FEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG-----GGMRFEGPSVPGGGLRIEGP 1023
                   + G   F GP G PG      GPL  +G     G   F+G   P G     GP
Sbjct: 351  GSAGAPGIAGAPGFPGPRGPPGPQ-GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 409

Query: 1024 LGQGGPR-FEGCHALRFD-------GQPGQPSL-----LPRFDGLHGQPGPRFERTP-GQ 1069
             G  GP   EG    R +       G PG+         P  DGL G  G   ER P G 
Sbjct: 410  QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 469

Query: 1070 PGPQRFDGPPGQQVQPRFDG 1089
             GP+  +G PG+  +P   G
Sbjct: 470  AGPKGANGDPGRPGEPGLPG 489



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 144/450 (32%), Positives = 168/450 (37%), Gaps = 92/450 (20%)

Query: 772  GPNKLSPRIDGPPTPASLRFD-GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGT 830
            GP K  P   GP      R D G  G+ G  GP   +G  G  G   P    GPPGP G 
Sbjct: 48   GP-KGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGL 106

Query: 831  -----------------------------PLRFEGPIGQAGGGGFR-FEGSPGLRFE-GS 859
                                         P+   GP G AG  G + F+G+PG   E G 
Sbjct: 107  GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGV 166

Query: 860  PGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQP-VGGLR-- 916
             G +   GP G P G    +G  G+P G     GP G P G   F    G P V G R  
Sbjct: 167  SGPMGPRGPPGPP-GKPGDDGEAGKP-GKAGERGPPG-PQGARGFPGTPGLPGVKGHRGY 223

Query: 917  --FEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGV-GMRFE-GPHGQSVAGLRFEGQ 972
               +G  G +GA     G  G PG      GP+  +G+ G R   GP G   AG R    
Sbjct: 224  PGLDGAKGEAGAP-GVKGESGSPGEN-GSPGPMGPRGLPGERGRTGPAG--AAGAR---- 275

Query: 973  HNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPG--GGLRIEGPLGQGGPR 1030
                 GN    GP G P       GP+   G      GP  PG  G     GP G  GP 
Sbjct: 276  -----GNDGQPGPAGPP-------GPVGPAG------GPGFPGAPGAKGEAGPTGARGP- 316

Query: 1031 FEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGV 1090
             EG    R  G+PG P   P   G  G PG     T G PG +   G PG    P F G 
Sbjct: 317  -EGAQGPR--GEPGTPG-SPGPAGASGNPG-----TDGIPGAKGSAGAPGIAGAPGFPG- 366

Query: 1091 PQRFDGPQHQQASRFDIPLGLQG-TRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQG 1149
            P+   GPQ         PLG +G T        + E     + GP   P G    A  +G
Sbjct: 367  PRGPPGPQGATG-----PLGPKGQTGEPGIAGFKGEQGPKGEPGPAG-PQGAPGPAGEEG 420

Query: 1150 LQFQRHEQIFDSPQGPNFNGPHG-PGNQSF 1178
             +  R E     P GP   G  G PGN+ F
Sbjct: 421  KRGARGEPGGVGPIGP--PGERGAPGNRGF 448



 Score = 39.3 bits (90), Expect = 0.030
 Identities = 52/162 (32%), Positives = 68/162 (41%), Gaps = 30/162 (18%)

Query: 713  LKRPRYEDSDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVARDGPTKMIFEG 772
            ++ P+    DK     P  R  GL  ++  T L +  P   GPS    A  GP      G
Sbjct: 1039 IQGPQGPRGDKGEAGEPGER--GLKGHRGFTGL-QGLPGPPGPSGDQGA-SGPA-----G 1089

Query: 773  PNKLSPRIDGPPTPASLR----FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPV 828
            P+   PR  GPP P         +G PG +G  GP    G  G+ G   P    GPPGP 
Sbjct: 1090 PS--GPR--GPPGPVGPSGKDGANGIPGPIGPPGP---RGRSGETGPAGPPGNPGPPGPP 1142

Query: 829  GTPLRFEGP---IGQAGGGGFRFEGSPGLRF---EGSPGGLR 864
            G P    GP   +    G G R +G   L++   + + GGLR
Sbjct: 1143 GPP----GPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLR 1180



 Score = 38.5 bits (88), Expect = 0.051
 Identities = 44/148 (29%), Positives = 52/148 (35%), Gaps = 25/148 (16%)

Query: 1041 GQPGQPSLLPRFDGLHGQPGPR---FERTP----------GQPGPQRFDGPPGQQVQPRF 1087
            GQ G+P  +    G  G PGP+    E+ P          G PGP+  DG PG    P  
Sbjct: 35   GQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP 94

Query: 1088 DGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPY--NDPPGNAFNA 1145
             G P    GP        +    + G  FD         V     GP     PPG A   
Sbjct: 95   PGPP----GPPGPPGLGGNFAAQMAG-GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 149

Query: 1146 PSQGLQFQRHEQIFDSPQGPNFNGPHGP 1173
              QG Q    E     P  P  +GP GP
Sbjct: 150  GPQGFQGNPGE-----PGEPGVSGPMGP 172


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  101 bits (251), Expect = 6e-21
 Identities = 133/376 (35%), Positives = 155/376 (41%), Gaps = 75/376 (19%)

Query: 753  DGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEG---- 808
            DGP  P   R  P     +GPN   P   GPP P     DG PG  G  G + F+G    
Sbjct: 781  DGPHGPPGERGLPGP---QGPNGF-PGPKGPPGPPGK--DGLPGHPGQRGEVGFQGKTGP 834

Query: 809  --------PQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE-GSPGLRFEGS 859
                    PQG  G   P+   G PGP G P   +G  G AG  G + + G PG   +  
Sbjct: 835  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGE-QGLPGTAGKEGTKGDPGPPGAPGKDG 893

Query: 860  PGGLR-FEGPGGQP--VGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLR 916
            P GLR F G  G P   GG   +G+ G P G     GP G P  G R     G P+G   
Sbjct: 894  PAGLRGFPGERGLPGTAGGPGLKGNEG-PSGP---PGPAGSP--GERGAAGSGGPIGPPG 947

Query: 917  FEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGV--GMRFEGPHG-QSVAGLRFEG 971
              G  GP GAA    G  G PG  G I   GP  + GV   +   GP G   VAG   +G
Sbjct: 948  RPGPQGPPGAA----GEKGVPGEKGPI---GPTGRDGVQGPVGLPGPAGPPGVAG--EDG 998

Query: 972  QHNQLG-----GNLRFEGPHGQPGVGIRFEGPL--VQQGGGMRFEGPSVPGGGLRIEGPL 1024
               ++G     G    +G HG PG      GP+  V Q G    +G   PG      GP 
Sbjct: 999  DKGEVGDPGQKGTKGNKGEHGPPGP----PGPIGPVGQPGAAGADGE--PGA----RGPQ 1048

Query: 1025 GQGGPR-FEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFER-TPGQPGPQRFDGPPGQQ 1082
            G  G +  EG     F+G PG         GL G PGP  E+   G  GP    GPPG  
Sbjct: 1049 GHFGAKGDEGTRG--FNGPPGP-------IGLQGLPGPSGEKGETGDVGPMGPPGPPG-- 1097

Query: 1083 VQPRFDGVPQRFDGPQ 1098
              PR    P   DGPQ
Sbjct: 1098 --PRGPAGPNGADGPQ 1111



 Score = 94.4 bits (233), Expect = 8e-19
 Identities = 136/417 (32%), Positives = 161/417 (38%), Gaps = 93/417 (22%)

Query: 773  PNKLSPR-IDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP 831
            P +  PR + GP  P  +   G PG  G  GP   +GP+G LG   P    GPPG  GTP
Sbjct: 517  PGESGPRGLLGPKGPPGI--PGPPGVRGMDGP---QGPKGSLG---PQGEPGPPGQQGTP 568

Query: 832  --LRFEGPIGQAGGGGFRF-EGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGG 888
                  GP G  G  G +  +G PGL   G PG    +GP G P       G  G P G 
Sbjct: 569  GTQGLPGPQGAIGPHGEKGPQGKPGL--PGMPGS---DGPPGHP-------GKEGPP-GT 615

Query: 889  LRFEGPHGQPVGGLRFDNPRG-QPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEG 945
               +GP G P G L +  PRG + V G+R   GH          G  G PG  G I  +G
Sbjct: 616  KGNQGPSG-PQGPLGYPGPRGVKGVDGIRGLKGHKGE------KGEDGFPGFKGDIGVKG 668

Query: 946  PLLQQGV-GMRF----EGPHGQS-------VAGLRFEGQHNQLG-----GNLRFEGPHGQ 988
               + GV G R     EGP G++         GL   G+  +LG     G    +GP G 
Sbjct: 669  DRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM--GEKGKLGVPGLPGYPGRQGPKGS 726

Query: 989  PGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSL 1048
             G    F G   ++ G     G S P G     GP GQ GPR     A    G  G    
Sbjct: 727  LGFP-GFPGASGEK-GARGLSGKSGPRGERGPTGPRGQRGPR----GATGKSGAKGTSG- 779

Query: 1049 LPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIP 1108
                DG HG PG R    PG  GP  F GP G    P  DG+P                 
Sbjct: 780  ---GDGPHGPPGER--GLPGPQGPNGFPGPKGPPGPPGKDGLP----------------- 817

Query: 1109 LGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
                      HP QR E     +TGP   PPG      + G      E+    P GP
Sbjct: 818  ---------GHPGQRGEVGFQGKTGP-PGPPGVVGPQGAAGETGPMGERGHPGPPGP 864



 Score = 91.3 bits (225), Expect = 7e-18
 Identities = 114/341 (33%), Positives = 137/341 (40%), Gaps = 43/341 (12%)

Query: 783  PPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP--LRFEGPIGQ 840
            P  P     DG PG  G  GP   +G QG  G   PL + GP G  G       +G  G+
Sbjct: 592  PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 651

Query: 841  AGGGGFR-FEGSPGLRFE----GSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPH 895
             G  GF  F+G  G++ +    G PG    +GP G P G     G  G P G +  +G  
Sbjct: 652  KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG-PKGRTGPTGDPGPP-GLMGEKGKL 709

Query: 896  GQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMR 955
            G P  GL     R  P G L F G  G SG      G  G  G      GP  ++G    
Sbjct: 710  GVP--GLPGYPGRQGPKGSLGFPGFPGASGEK----GARGLSGKS----GPRGERGP--- 756

Query: 956  FEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPG 1015
              GP GQ   G R     +   G    +GPHG PG     E  L    G   F GP  P 
Sbjct: 757  -TGPRGQR--GPRGATGKSGAKGTSGGDGPHGPPG-----ERGLPGPQGPNGFPGPKGPP 808

Query: 1016 GGLRIEGPLGQGGPRFEGCHALRFDGQ---PGQPSLLPRFDGLHGQPGPRFERTPGQPGP 1072
            G    +G  G  G R E    + F G+   PG P ++    G  G+ GP  ER  G PGP
Sbjct: 809  GPPGKDGLPGHPGQRGE----VGFQGKTGPPGPPGVVGP-QGAAGETGPMGER--GHPGP 861

Query: 1073 QRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQG 1113
                GPPG+Q  P   G       P    A   D P GL+G
Sbjct: 862  P---GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 899



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 119/390 (30%), Positives = 149/390 (38%), Gaps = 79/390 (20%)

Query: 762  RDGPTKMI-FEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLR 820
            +DGP  +  F G   L     GP         G+ G  G  GP    G +G  G G P+ 
Sbjct: 891  KDGPAGLRGFPGERGLPGTAGGPG------LKGNEGPSGPPGPAGSPGERGAAGSGGPIG 944

Query: 821  FEGPPGPVGTPLRF--------EGPIGQAGGGGFRF-------EGSPGLRFE-------G 858
              G PGP G P           +GPIG  G  G +         G PG+  E       G
Sbjct: 945  PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVG 1004

Query: 859  SPGGLRFEGPGGQ-----------PVGGLRFEGHRGQP--------------VGGLRFEG 893
             PG    +G  G+           PVG     G  G+P               G   F G
Sbjct: 1005 DPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG 1064

Query: 894  PHGQPVGGLRFDNPRGQ-----PVGGLRFEGGHGPSGAA--IRFDGPHGQPGGGIRFEGP 946
            P G P+G      P G+      VG +   G  GP G A     DGP G P GG+   GP
Sbjct: 1065 PPG-PIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP-GGVGNLGP 1122

Query: 947  LLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG--G 1004
              ++G       P  Q   G++  G   + G     +G  GQPG      GP   +G  G
Sbjct: 1123 PGEKGEPGESGSPGIQGEPGVK--GPRGERGE----KGESGQPGE----PGPPGPKGPTG 1172

Query: 1005 GMRFEGPSVPGGGLRIEGPLGQGGPR-FEGCHALR-FDGQPGQPSLLPRFDGLHGQPGPR 1062
                +G   P G     GP G+GGPR  +G    R  DG+PGQP   P   G +G PGP 
Sbjct: 1173 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG-SPGPTGENGPPGPL 1231

Query: 1063 FERTP-GQPGPQRFDGPPGQQVQPRFDGVP 1091
             +R P G PG +   G  G +  P   G P
Sbjct: 1232 GKRGPAGSPGSEGRQGGKGAKGDPGAIGAP 1261



 Score = 81.3 bits (199), Expect = 7e-15
 Identities = 135/453 (29%), Positives = 166/453 (36%), Gaps = 103/453 (22%)

Query: 703  QRSPFNDRFPLKRPRYEDSDKPFVDSPASRFAGLDTNQRLTALAE----DRPLFDGPSRP 758
            QRSP      L RP+ ++      D        +  +  L  L E     R L      P
Sbjct: 245  QRSPQQQPSRLHRPQNQEPQSQ--DPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEP 302

Query: 759  SVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCP 818
            +V   G   M+ EGP        GP  PA L   G PG  G  GP+   G +G  G    
Sbjct: 303  AVLEPG---MLVEGP-------PGPEGPAGLI--GPPGIQGNPGPVGDPGERGPPGRAGL 350

Query: 819  LRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEG--SPGGLRFEGPGGQPVGGL 876
               +G PGP GT L      G  GG       +   + +       L   GP G      
Sbjct: 351  PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGP----- 405

Query: 877  RFEGHRGQPVGGLRFEGPHGQPVG-GLRFDNPRGQPVGGLRFEGGHGPSGAAIR-----F 930
               G+ G+P       GP GQP   GL+ ++    P G    +G  GP G A R      
Sbjct: 406  --MGYTGRP-------GPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 456

Query: 931  DGPHGQPG-----GGIRFEG-PLLQQGVGMR-------FEGPHGQSVAGLRFEGQHNQLG 977
            DG  G PG     G   F+G P L    G R         GP G+   G R  G   ++G
Sbjct: 457  DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED--GER--GDDGEIG 512

Query: 978  --------GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGP 1029
                    G     GP G PG+     GP   +G     +GP  P G L   GP G+ GP
Sbjct: 513  PRGLPGESGPRGLLGPKGPPGI----PGPPGVRG----MDGPQGPKGSL---GPQGEPGP 561

Query: 1030 RFEGCHALRFDGQPGQPSL--LPRFDGL---HGQPGPRFERTPGQPGPQRFDGPPGQQVQ 1084
                       GQ G P    LP   G    HG+ GP  +  PG PG    DGPPG    
Sbjct: 562  ----------PGQQGTPGTQGLPGPQGAIGPHGEKGP--QGKPGLPGMPGSDGPPG---H 606

Query: 1085 PRFDGVP--QRFDGPQHQQASRFDIPLGLQGTR 1115
            P  +G P  +   GP   Q      PLG  G R
Sbjct: 607  PGKEGPPGTKGNQGPSGPQG-----PLGYPGPR 634



 Score = 81.3 bits (199), Expect = 7e-15
 Identities = 102/319 (31%), Positives = 123/319 (38%), Gaps = 89/319 (27%)

Query: 781  DGPP-TPASLRFDGSPGQMGGGGPLRFEGPQG---------QLGGGCPLRFEGPPGPVGT 830
            DGP   P  + F G PG  G GGP   +G +G         Q G   P    GPPGP+G 
Sbjct: 1174 DGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1233

Query: 831  PLRFEGPIGQAGG----GGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPV 886
                 GP G  G     GG   +G PG    G+PG     GP G P G    +G RG P 
Sbjct: 1234 ----RGPAGSPGSEGRQGGKGAKGDPGA--IGAPGKTGPVGPAG-PAGKPGPDGLRGLP- 1285

Query: 887  GGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGP 946
            G +   G  G+P G      P G PVG     G  G +GA     G  G PG        
Sbjct: 1286 GSV---GQQGRP-GATGQAGPPG-PVGPPGLPGLRGDAGA----KGEKGHPG-------- 1328

Query: 947  LLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGM 1006
                 +G+   GP G+       +G+    G      GP G PG           Q G M
Sbjct: 1329 ----LIGL--IGPPGE-------QGEKGDRG----LPGPQGSPG-----------QKGEM 1360

Query: 1007 RFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERT 1066
               G S         GP+G GGP           G PG P+      G  G  GP+ E+ 
Sbjct: 1361 GIPGAS---------GPIGPGGP----------PGLPG-PAGPKGAKGATGPGGPKGEK- 1399

Query: 1067 PGQPGPQRFDGPPGQQVQP 1085
             G  GP    GPPG+ +QP
Sbjct: 1400 -GVQGPPGHPGPPGEVIQP 1417



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 147/486 (30%), Positives = 167/486 (34%), Gaps = 113/486 (23%)

Query: 759  SVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQL----- 813
            S   DGP     EGP   +     P  P  +   G  G  G  G    +GP+G L     
Sbjct: 678  SRGEDGP-----EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 732

Query: 814  -------------GGGCPLRFEGPPGPVGTPLRFEGPIGQAG-------GGGFRFEGSPG 853
                         G   P    GP GP G      GP G  G        GG    G PG
Sbjct: 733  PGASGEKGARGLSGKSGPRGERGPTGPRGQ----RGPRGATGKSGAKGTSGGDGPHGPPG 788

Query: 854  LR-FEGSPGGLRFEGPGGQ--PVGGLRFEGHRGQ-----------PVGGLRFEGPHGQ-- 897
             R   G  G   F GP G   P G     GH GQ           P G     GP G   
Sbjct: 789  ERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG 848

Query: 898  ---PVGGLRFDNPRGQP--------VGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGP 946
               P+G      P G P         G    +G  GP GA  + DGP G  G       P
Sbjct: 849  ETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK-DGPAGLRGFPGERGLP 907

Query: 947  LLQQGVGMR-FEGPHG-QSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG- 1003
                G G++  EGP G    AG   E      GG +   GP G+PG     +GP    G 
Sbjct: 908  GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPI---GPPGRPGP----QGPPGAAGE 960

Query: 1004 -GGMRFEGPSVPGGGLRIEGPLGQGGPRF-EGCHALRFD----GQPGQPSLLPRFDGLHG 1057
             G    +GP  P G   ++GP+G  GP    G      D    G PGQ        G HG
Sbjct: 961  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGN-KGEHG 1019

Query: 1058 QPGPRFERTP-GQPGPQRFDGPPGQQ-VQPRF----DGVPQRFDGPQHQQASRFDIPLGL 1111
             PGP     P GQPG    DG PG +  Q  F    D   + F+GP          P+GL
Sbjct: 1020 PPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG--------PIGL 1071

Query: 1112 QGTRFDNHPSQRLESVSFNQTGPYN--DPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNG 1169
            QG      P    E       GP     PPG    A   G          D PQGP    
Sbjct: 1072 QGL-----PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA---------DGPQGP---- 1113

Query: 1170 PHGPGN 1175
            P G GN
Sbjct: 1114 PGGVGN 1119



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 32/88 (36%), Positives = 36/88 (40%), Gaps = 9/88 (10%)

Query: 782  GPPTPASLRFDGSP-GQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP-IG 839
            GP  P  L     P G  G  GP    GP+G+ G   P    GPPG V  PL  + P   
Sbjct: 1370 GPGGPPGLPGPAGPKGAKGATGP---GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKT 1426

Query: 840  QAGGGGFRF----EGSPGLRFEGSPGGL 863
            +    G R     E  P     GSPGGL
Sbjct: 1427 RRSVDGSRLMQEDEAIPTGGAPGSPGGL 1454


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  101 bits (251), Expect = 6e-21
 Identities = 133/376 (35%), Positives = 155/376 (41%), Gaps = 75/376 (19%)

Query: 753  DGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEG---- 808
            DGP  P   R  P     +GPN   P   GPP P     DG PG  G  G + F+G    
Sbjct: 760  DGPHGPPGERGLPGP---QGPNGF-PGPKGPPGPPGK--DGLPGHPGQRGEVGFQGKTGP 813

Query: 809  --------PQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE-GSPGLRFEGS 859
                    PQG  G   P+   G PGP G P   +G  G AG  G + + G PG   +  
Sbjct: 814  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGE-QGLPGTAGKEGTKGDPGPPGAPGKDG 872

Query: 860  PGGLR-FEGPGGQP--VGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLR 916
            P GLR F G  G P   GG   +G+ G P G     GP G P  G R     G P+G   
Sbjct: 873  PAGLRGFPGERGLPGTAGGPGLKGNEG-PSGP---PGPAGSP--GERGAAGSGGPIGPPG 926

Query: 917  FEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGV--GMRFEGPHG-QSVAGLRFEG 971
              G  GP GAA    G  G PG  G I   GP  + GV   +   GP G   VAG   +G
Sbjct: 927  RPGPQGPPGAA----GEKGVPGEKGPI---GPTGRDGVQGPVGLPGPAGPPGVAG--EDG 977

Query: 972  QHNQLG-----GNLRFEGPHGQPGVGIRFEGPL--VQQGGGMRFEGPSVPGGGLRIEGPL 1024
               ++G     G    +G HG PG      GP+  V Q G    +G   PG      GP 
Sbjct: 978  DKGEVGDPGQKGTKGNKGEHGPPGP----PGPIGPVGQPGAAGADGE--PGA----RGPQ 1027

Query: 1025 GQGGPR-FEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFER-TPGQPGPQRFDGPPGQQ 1082
            G  G +  EG     F+G PG         GL G PGP  E+   G  GP    GPPG  
Sbjct: 1028 GHFGAKGDEGTRG--FNGPPGP-------IGLQGLPGPSGEKGETGDVGPMGPPGPPG-- 1076

Query: 1083 VQPRFDGVPQRFDGPQ 1098
              PR    P   DGPQ
Sbjct: 1077 --PRGPAGPNGADGPQ 1090



 Score = 94.4 bits (233), Expect = 8e-19
 Identities = 136/417 (32%), Positives = 161/417 (38%), Gaps = 93/417 (22%)

Query: 773  PNKLSPR-IDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP 831
            P +  PR + GP  P  +   G PG  G  GP   +GP+G LG   P    GPPG  GTP
Sbjct: 496  PGESGPRGLLGPKGPPGI--PGPPGVRGMDGP---QGPKGSLG---PQGEPGPPGQQGTP 547

Query: 832  --LRFEGPIGQAGGGGFRF-EGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGG 888
                  GP G  G  G +  +G PGL   G PG    +GP G P       G  G P G 
Sbjct: 548  GTQGLPGPQGAIGPHGEKGPQGKPGL--PGMPGS---DGPPGHP-------GKEGPP-GT 594

Query: 889  LRFEGPHGQPVGGLRFDNPRG-QPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEG 945
               +GP G P G L +  PRG + V G+R   GH          G  G PG  G I  +G
Sbjct: 595  KGNQGPSG-PQGPLGYPGPRGVKGVDGIRGLKGHKGE------KGEDGFPGFKGDIGVKG 647

Query: 946  PLLQQGV-GMRF----EGPHGQS-------VAGLRFEGQHNQLG-----GNLRFEGPHGQ 988
               + GV G R     EGP G++         GL   G+  +LG     G    +GP G 
Sbjct: 648  DRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM--GEKGKLGVPGLPGYPGRQGPKGS 705

Query: 989  PGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSL 1048
             G    F G   ++ G     G S P G     GP GQ GPR     A    G  G    
Sbjct: 706  LGFP-GFPGASGEK-GARGLSGKSGPRGERGPTGPRGQRGPR----GATGKSGAKGTSG- 758

Query: 1049 LPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIP 1108
                DG HG PG R    PG  GP  F GP G    P  DG+P                 
Sbjct: 759  ---GDGPHGPPGER--GLPGPQGPNGFPGPKGPPGPPGKDGLP----------------- 796

Query: 1109 LGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
                      HP QR E     +TGP   PPG      + G      E+    P GP
Sbjct: 797  ---------GHPGQRGEVGFQGKTGP-PGPPGVVGPQGAAGETGPMGERGHPGPPGP 843



 Score = 91.3 bits (225), Expect = 7e-18
 Identities = 114/341 (33%), Positives = 137/341 (40%), Gaps = 43/341 (12%)

Query: 783  PPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP--LRFEGPIGQ 840
            P  P     DG PG  G  GP   +G QG  G   PL + GP G  G       +G  G+
Sbjct: 571  PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 630

Query: 841  AGGGGFR-FEGSPGLRFE----GSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPH 895
             G  GF  F+G  G++ +    G PG    +GP G P G     G  G P G +  +G  
Sbjct: 631  KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG-PKGRTGPTGDPGPP-GLMGEKGKL 688

Query: 896  GQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMR 955
            G P  GL     R  P G L F G  G SG      G  G  G      GP  ++G    
Sbjct: 689  GVP--GLPGYPGRQGPKGSLGFPGFPGASGEK----GARGLSGKS----GPRGERGP--- 735

Query: 956  FEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPG 1015
              GP GQ   G R     +   G    +GPHG PG     E  L    G   F GP  P 
Sbjct: 736  -TGPRGQR--GPRGATGKSGAKGTSGGDGPHGPPG-----ERGLPGPQGPNGFPGPKGPP 787

Query: 1016 GGLRIEGPLGQGGPRFEGCHALRFDGQ---PGQPSLLPRFDGLHGQPGPRFERTPGQPGP 1072
            G    +G  G  G R E    + F G+   PG P ++    G  G+ GP  ER  G PGP
Sbjct: 788  GPPGKDGLPGHPGQRGE----VGFQGKTGPPGPPGVVGP-QGAAGETGPMGER--GHPGP 840

Query: 1073 QRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQG 1113
                GPPG+Q  P   G       P    A   D P GL+G
Sbjct: 841  P---GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 878



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 119/390 (30%), Positives = 149/390 (38%), Gaps = 79/390 (20%)

Query: 762  RDGPTKMI-FEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLR 820
            +DGP  +  F G   L     GP         G+ G  G  GP    G +G  G G P+ 
Sbjct: 870  KDGPAGLRGFPGERGLPGTAGGPG------LKGNEGPSGPPGPAGSPGERGAAGSGGPIG 923

Query: 821  FEGPPGPVGTPLRF--------EGPIGQAGGGGFRF-------EGSPGLRFE-------G 858
              G PGP G P           +GPIG  G  G +         G PG+  E       G
Sbjct: 924  PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVG 983

Query: 859  SPGGLRFEGPGGQ-----------PVGGLRFEGHRGQP--------------VGGLRFEG 893
             PG    +G  G+           PVG     G  G+P               G   F G
Sbjct: 984  DPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG 1043

Query: 894  PHGQPVGGLRFDNPRGQ-----PVGGLRFEGGHGPSGAA--IRFDGPHGQPGGGIRFEGP 946
            P G P+G      P G+      VG +   G  GP G A     DGP G P GG+   GP
Sbjct: 1044 PPG-PIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP-GGVGNLGP 1101

Query: 947  LLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG--G 1004
              ++G       P  Q   G++  G   + G     +G  GQPG      GP   +G  G
Sbjct: 1102 PGEKGEPGESGSPGIQGEPGVK--GPRGERGE----KGESGQPGE----PGPPGPKGPTG 1151

Query: 1005 GMRFEGPSVPGGGLRIEGPLGQGGPR-FEGCHALR-FDGQPGQPSLLPRFDGLHGQPGPR 1062
                +G   P G     GP G+GGPR  +G    R  DG+PGQP   P   G +G PGP 
Sbjct: 1152 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG-SPGPTGENGPPGPL 1210

Query: 1063 FERTP-GQPGPQRFDGPPGQQVQPRFDGVP 1091
             +R P G PG +   G  G +  P   G P
Sbjct: 1211 GKRGPAGSPGSEGRQGGKGAKGDPGAIGAP 1240



 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 133/449 (29%), Positives = 164/449 (36%), Gaps = 116/449 (25%)

Query: 703  QRSPFNDRFPLKRPRYEDSDKPFVDSPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVAR 762
            QRSP      L RP+ ++        P     GL   +   A+ E   L +GP  P    
Sbjct: 245  QRSPQQQPSRLHRPQNQEPQSQAAHGPR----GLKGEKGEPAVLEPGMLVEGPPGP---- 296

Query: 763  DGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFE 822
            +GP  +I  GP    P I G P P      G PG+ G  G     G             +
Sbjct: 297  EGPAGLI--GP----PGIQGNPGPV-----GDPGERGPPGRAGLPGS------------D 333

Query: 823  GPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEG--SPGGLRFEGPGGQPVGGLRFEG 880
            G PGP GT L      G  GG       +   + +       L   GP G         G
Sbjct: 334  GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGP-------MG 386

Query: 881  HRGQPVGGLRFEGPHGQPVG-GLRFDNPRGQPVGGLRFEGGHGPSGAAIR-----FDGPH 934
            + G+P       GP GQP   GL+ ++    P G    +G  GP G A R      DG  
Sbjct: 387  YTGRP-------GPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 439

Query: 935  GQPG-----GGIRFEG-PLLQQGVGMR-------FEGPHGQSVAGLRFEGQHNQLG---- 977
            G PG     G   F+G P L    G R         GP G+   G R  G   ++G    
Sbjct: 440  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED--GER--GDDGEIGPRGL 495

Query: 978  ----GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEG 1033
                G     GP G PG+     GP   +G     +GP  P G L   GP G+ GP    
Sbjct: 496  PGESGPRGLLGPKGPPGI----PGPPGVRG----MDGPQGPKGSL---GPQGEPGP---- 540

Query: 1034 CHALRFDGQPGQPSL--LPRFDGL---HGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFD 1088
                   GQ G P    LP   G    HG+ GP  +  PG PG    DGPPG    P  +
Sbjct: 541  ------PGQQGTPGTQGLPGPQGAIGPHGEKGP--QGKPGLPGMPGSDGPPG---HPGKE 589

Query: 1089 GVP--QRFDGPQHQQASRFDIPLGLQGTR 1115
            G P  +   GP   Q      PLG  G R
Sbjct: 590  GPPGTKGNQGPSGPQG-----PLGYPGPR 613



 Score = 81.3 bits (199), Expect = 7e-15
 Identities = 102/319 (31%), Positives = 123/319 (38%), Gaps = 89/319 (27%)

Query: 781  DGPP-TPASLRFDGSPGQMGGGGPLRFEGPQG---------QLGGGCPLRFEGPPGPVGT 830
            DGP   P  + F G PG  G GGP   +G +G         Q G   P    GPPGP+G 
Sbjct: 1153 DGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1212

Query: 831  PLRFEGPIGQAGG----GGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPV 886
                 GP G  G     GG   +G PG    G+PG     GP G P G    +G RG P 
Sbjct: 1213 ----RGPAGSPGSEGRQGGKGAKGDPGA--IGAPGKTGPVGPAG-PAGKPGPDGLRGLP- 1264

Query: 887  GGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGP 946
            G +   G  G+P G      P G PVG     G  G +GA     G  G PG        
Sbjct: 1265 GSV---GQQGRP-GATGQAGPPG-PVGPPGLPGLRGDAGA----KGEKGHPG-------- 1307

Query: 947  LLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGM 1006
                 +G+   GP G+       +G+    G      GP G PG           Q G M
Sbjct: 1308 ----LIGL--IGPPGE-------QGEKGDRG----LPGPQGSPG-----------QKGEM 1339

Query: 1007 RFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERT 1066
               G S         GP+G GGP           G PG P+      G  G  GP+ E+ 
Sbjct: 1340 GIPGAS---------GPIGPGGP----------PGLPG-PAGPKGAKGATGPGGPKGEK- 1378

Query: 1067 PGQPGPQRFDGPPGQQVQP 1085
             G  GP    GPPG+ +QP
Sbjct: 1379 -GVQGPPGHPGPPGEVIQP 1396



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 147/486 (30%), Positives = 167/486 (34%), Gaps = 113/486 (23%)

Query: 759  SVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQL----- 813
            S   DGP     EGP   +     P  P  +   G  G  G  G    +GP+G L     
Sbjct: 657  SRGEDGP-----EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 711

Query: 814  -------------GGGCPLRFEGPPGPVGTPLRFEGPIGQAG-------GGGFRFEGSPG 853
                         G   P    GP GP G      GP G  G        GG    G PG
Sbjct: 712  PGASGEKGARGLSGKSGPRGERGPTGPRGQ----RGPRGATGKSGAKGTSGGDGPHGPPG 767

Query: 854  LR-FEGSPGGLRFEGPGGQ--PVGGLRFEGHRGQ-----------PVGGLRFEGPHGQ-- 897
             R   G  G   F GP G   P G     GH GQ           P G     GP G   
Sbjct: 768  ERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG 827

Query: 898  ---PVGGLRFDNPRGQP--------VGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGP 946
               P+G      P G P         G    +G  GP GA  + DGP G  G       P
Sbjct: 828  ETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK-DGPAGLRGFPGERGLP 886

Query: 947  LLQQGVGMR-FEGPHG-QSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG- 1003
                G G++  EGP G    AG   E      GG +   GP G+PG     +GP    G 
Sbjct: 887  GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPI---GPPGRPGP----QGPPGAAGE 939

Query: 1004 -GGMRFEGPSVPGGGLRIEGPLGQGGPRF-EGCHALRFD----GQPGQPSLLPRFDGLHG 1057
             G    +GP  P G   ++GP+G  GP    G      D    G PGQ        G HG
Sbjct: 940  KGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGN-KGEHG 998

Query: 1058 QPGPRFERTP-GQPGPQRFDGPPGQQ-VQPRF----DGVPQRFDGPQHQQASRFDIPLGL 1111
             PGP     P GQPG    DG PG +  Q  F    D   + F+GP          P+GL
Sbjct: 999  PPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG--------PIGL 1050

Query: 1112 QGTRFDNHPSQRLESVSFNQTGPYN--DPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNG 1169
            QG      P    E       GP     PPG    A   G          D PQGP    
Sbjct: 1051 QGL-----PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA---------DGPQGP---- 1092

Query: 1170 PHGPGN 1175
            P G GN
Sbjct: 1093 PGGVGN 1098



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 32/88 (36%), Positives = 36/88 (40%), Gaps = 9/88 (10%)

Query: 782  GPPTPASLRFDGSP-GQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP-IG 839
            GP  P  L     P G  G  GP    GP+G+ G   P    GPPG V  PL  + P   
Sbjct: 1349 GPGGPPGLPGPAGPKGAKGATGP---GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKT 1405

Query: 840  QAGGGGFRF----EGSPGLRFEGSPGGL 863
            +    G R     E  P     GSPGGL
Sbjct: 1406 RRSVDGSRLMQEDEAIPTGGAPGSPGGL 1433


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  101 bits (251), Expect = 6e-21
 Identities = 133/376 (35%), Positives = 155/376 (41%), Gaps = 75/376 (19%)

Query: 753  DGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEG---- 808
            DGP  P   R  P     +GPN   P   GPP P     DG PG  G  G + F+G    
Sbjct: 867  DGPHGPPGERGLPGP---QGPNGF-PGPKGPPGPPGK--DGLPGHPGQRGEVGFQGKTGP 920

Query: 809  --------PQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE-GSPGLRFEGS 859
                    PQG  G   P+   G PGP G P   +G  G AG  G + + G PG   +  
Sbjct: 921  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGE-QGLPGTAGKEGTKGDPGPPGAPGKDG 979

Query: 860  PGGLR-FEGPGGQP--VGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLR 916
            P GLR F G  G P   GG   +G+ G P G     GP G P  G R     G P+G   
Sbjct: 980  PAGLRGFPGERGLPGTAGGPGLKGNEG-PSGP---PGPAGSP--GERGAAGSGGPIGPPG 1033

Query: 917  FEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGV--GMRFEGPHG-QSVAGLRFEG 971
              G  GP GAA    G  G PG  G I   GP  + GV   +   GP G   VAG   +G
Sbjct: 1034 RPGPQGPPGAA----GEKGVPGEKGPI---GPTGRDGVQGPVGLPGPAGPPGVAG--EDG 1084

Query: 972  QHNQLG-----GNLRFEGPHGQPGVGIRFEGPL--VQQGGGMRFEGPSVPGGGLRIEGPL 1024
               ++G     G    +G HG PG      GP+  V Q G    +G   PG      GP 
Sbjct: 1085 DKGEVGDPGQKGTKGNKGEHGPPGP----PGPIGPVGQPGAAGADGE--PGA----RGPQ 1134

Query: 1025 GQGGPR-FEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFER-TPGQPGPQRFDGPPGQQ 1082
            G  G +  EG     F+G PG         GL G PGP  E+   G  GP    GPPG  
Sbjct: 1135 GHFGAKGDEGTRG--FNGPPGP-------IGLQGLPGPSGEKGETGDVGPMGPPGPPG-- 1183

Query: 1083 VQPRFDGVPQRFDGPQ 1098
              PR    P   DGPQ
Sbjct: 1184 --PRGPAGPNGADGPQ 1197



 Score = 94.4 bits (233), Expect = 8e-19
 Identities = 136/417 (32%), Positives = 161/417 (38%), Gaps = 93/417 (22%)

Query: 773  PNKLSPR-IDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP 831
            P +  PR + GP  P  +   G PG  G  GP   +GP+G LG   P    GPPG  GTP
Sbjct: 603  PGESGPRGLLGPKGPPGI--PGPPGVRGMDGP---QGPKGSLG---PQGEPGPPGQQGTP 654

Query: 832  --LRFEGPIGQAGGGGFRF-EGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGG 888
                  GP G  G  G +  +G PGL   G PG    +GP G P       G  G P G 
Sbjct: 655  GTQGLPGPQGAIGPHGEKGPQGKPGL--PGMPGS---DGPPGHP-------GKEGPP-GT 701

Query: 889  LRFEGPHGQPVGGLRFDNPRG-QPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEG 945
               +GP G P G L +  PRG + V G+R   GH          G  G PG  G I  +G
Sbjct: 702  KGNQGPSG-PQGPLGYPGPRGVKGVDGIRGLKGHKGE------KGEDGFPGFKGDIGVKG 754

Query: 946  PLLQQGV-GMRF----EGPHGQS-------VAGLRFEGQHNQLG-----GNLRFEGPHGQ 988
               + GV G R     EGP G++         GL   G+  +LG     G    +GP G 
Sbjct: 755  DRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM--GEKGKLGVPGLPGYPGRQGPKGS 812

Query: 989  PGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSL 1048
             G    F G   ++ G     G S P G     GP GQ GPR     A    G  G    
Sbjct: 813  LGFP-GFPGASGEK-GARGLSGKSGPRGERGPTGPRGQRGPR----GATGKSGAKGTSG- 865

Query: 1049 LPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIP 1108
                DG HG PG R    PG  GP  F GP G    P  DG+P                 
Sbjct: 866  ---GDGPHGPPGER--GLPGPQGPNGFPGPKGPPGPPGKDGLP----------------- 903

Query: 1109 LGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
                      HP QR E     +TGP   PPG      + G      E+    P GP
Sbjct: 904  ---------GHPGQRGEVGFQGKTGP-PGPPGVVGPQGAAGETGPMGERGHPGPPGP 950



 Score = 91.3 bits (225), Expect = 7e-18
 Identities = 114/341 (33%), Positives = 137/341 (40%), Gaps = 43/341 (12%)

Query: 783  PPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP--LRFEGPIGQ 840
            P  P     DG PG  G  GP   +G QG  G   PL + GP G  G       +G  G+
Sbjct: 678  PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 737

Query: 841  AGGGGFR-FEGSPGLRFE----GSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPH 895
             G  GF  F+G  G++ +    G PG    +GP G P G     G  G P G +  +G  
Sbjct: 738  KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG-PKGRTGPTGDPGPP-GLMGEKGKL 795

Query: 896  GQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMR 955
            G P  GL     R  P G L F G  G SG      G  G  G      GP  ++G    
Sbjct: 796  GVP--GLPGYPGRQGPKGSLGFPGFPGASGEK----GARGLSGKS----GPRGERGP--- 842

Query: 956  FEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPG 1015
              GP GQ   G R     +   G    +GPHG PG     E  L    G   F GP  P 
Sbjct: 843  -TGPRGQR--GPRGATGKSGAKGTSGGDGPHGPPG-----ERGLPGPQGPNGFPGPKGPP 894

Query: 1016 GGLRIEGPLGQGGPRFEGCHALRFDGQ---PGQPSLLPRFDGLHGQPGPRFERTPGQPGP 1072
            G    +G  G  G R E    + F G+   PG P ++    G  G+ GP  ER  G PGP
Sbjct: 895  GPPGKDGLPGHPGQRGE----VGFQGKTGPPGPPGVVGP-QGAAGETGPMGER--GHPGP 947

Query: 1073 QRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQG 1113
                GPPG+Q  P   G       P    A   D P GL+G
Sbjct: 948  P---GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 985



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 119/390 (30%), Positives = 149/390 (38%), Gaps = 79/390 (20%)

Query: 762  RDGPTKMI-FEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLR 820
            +DGP  +  F G   L     GP         G+ G  G  GP    G +G  G G P+ 
Sbjct: 977  KDGPAGLRGFPGERGLPGTAGGPG------LKGNEGPSGPPGPAGSPGERGAAGSGGPIG 1030

Query: 821  FEGPPGPVGTPLRF--------EGPIGQAGGGGFRF-------EGSPGLRFE-------G 858
              G PGP G P           +GPIG  G  G +         G PG+  E       G
Sbjct: 1031 PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVG 1090

Query: 859  SPGGLRFEGPGGQ-----------PVGGLRFEGHRGQP--------------VGGLRFEG 893
             PG    +G  G+           PVG     G  G+P               G   F G
Sbjct: 1091 DPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG 1150

Query: 894  PHGQPVGGLRFDNPRGQ-----PVGGLRFEGGHGPSGAA--IRFDGPHGQPGGGIRFEGP 946
            P G P+G      P G+      VG +   G  GP G A     DGP G P GG+   GP
Sbjct: 1151 PPG-PIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP-GGVGNLGP 1208

Query: 947  LLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG--G 1004
              ++G       P  Q   G++  G   + G     +G  GQPG      GP   +G  G
Sbjct: 1209 PGEKGEPGESGSPGIQGEPGVK--GPRGERGE----KGESGQPGE----PGPPGPKGPTG 1258

Query: 1005 GMRFEGPSVPGGGLRIEGPLGQGGPR-FEGCHALR-FDGQPGQPSLLPRFDGLHGQPGPR 1062
                +G   P G     GP G+GGPR  +G    R  DG+PGQP   P   G +G PGP 
Sbjct: 1259 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG-SPGPTGENGPPGPL 1317

Query: 1063 FERTP-GQPGPQRFDGPPGQQVQPRFDGVP 1091
             +R P G PG +   G  G +  P   G P
Sbjct: 1318 GKRGPAGSPGSEGRQGGKGAKGDPGAIGAP 1347



 Score = 81.3 bits (199), Expect = 7e-15
 Identities = 102/319 (31%), Positives = 123/319 (38%), Gaps = 89/319 (27%)

Query: 781  DGPP-TPASLRFDGSPGQMGGGGPLRFEGPQG---------QLGGGCPLRFEGPPGPVGT 830
            DGP   P  + F G PG  G GGP   +G +G         Q G   P    GPPGP+G 
Sbjct: 1260 DGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1319

Query: 831  PLRFEGPIGQAGG----GGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPV 886
                 GP G  G     GG   +G PG    G+PG     GP G P G    +G RG P 
Sbjct: 1320 ----RGPAGSPGSEGRQGGKGAKGDPGA--IGAPGKTGPVGPAG-PAGKPGPDGLRGLP- 1371

Query: 887  GGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGP 946
            G +   G  G+P G      P G PVG     G  G +GA     G  G PG        
Sbjct: 1372 GSV---GQQGRP-GATGQAGPPG-PVGPPGLPGLRGDAGA----KGEKGHPG-------- 1414

Query: 947  LLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGM 1006
                 +G+   GP G+       +G+    G      GP G PG           Q G M
Sbjct: 1415 ----LIGL--IGPPGE-------QGEKGDRG----LPGPQGSPG-----------QKGEM 1446

Query: 1007 RFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERT 1066
               G S         GP+G GGP           G PG P+      G  G  GP+ E+ 
Sbjct: 1447 GIPGAS---------GPIGPGGP----------PGLPG-PAGPKGAKGATGPGGPKGEK- 1485

Query: 1067 PGQPGPQRFDGPPGQQVQP 1085
             G  GP    GPPG+ +QP
Sbjct: 1486 -GVQGPPGHPGPPGEVIQP 1503



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 122/394 (30%), Positives = 148/394 (37%), Gaps = 97/394 (24%)

Query: 758  PSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGC 817
            P+V   G   M+ EGP        GP  PA L   G PG  G  GP+   G +G  G   
Sbjct: 388  PAVLEPG---MLVEGP-------PGPEGPAGLI--GPPGIQGNPGPVGDPGERGPPGRAG 435

Query: 818  PLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEG--SPGGLRFEGPGGQPVGG 875
                +G PGP GT L      G  GG       +   + +       L   GP G     
Sbjct: 436  LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGP---- 491

Query: 876  LRFEGHRGQPVGGLRFEGPHGQPVG-GLRFDNPRGQPVGGLRFEGGHGPSGAAIR----- 929
                G+ G+P       GP GQP   GL+ ++    P G    +G  GP G A R     
Sbjct: 492  ---MGYTGRP-------GPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG 541

Query: 930  FDGPHGQPG-----GGIRFEG-PLLQQGVGMR-------FEGPHGQSVAGLRFEGQHNQL 976
             DG  G PG     G   F+G P L    G R         GP G+   G R  G   ++
Sbjct: 542  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED--GER--GDDGEI 597

Query: 977  G--------GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGG 1028
            G        G     GP G PG+     GP   +G     +GP  P G L   GP G+ G
Sbjct: 598  GPRGLPGESGPRGLLGPKGPPGI----PGPPGVRG----MDGPQGPKGSL---GPQGEPG 646

Query: 1029 PRFEGCHALRFDGQPGQPSL--LPRFDGL---HGQPGPRFERTPGQPGPQRFDGPPGQQV 1083
            P           GQ G P    LP   G    HG+ GP  +  PG PG    DGPPG   
Sbjct: 647  P----------PGQQGTPGTQGLPGPQGAIGPHGEKGP--QGKPGLPGMPGSDGPPG--- 691

Query: 1084 QPRFDGVP--QRFDGPQHQQASRFDIPLGLQGTR 1115
             P  +G P  +   GP   Q      PLG  G R
Sbjct: 692  HPGKEGPPGTKGNQGPSGPQG-----PLGYPGPR 720



 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 121/415 (29%), Positives = 149/415 (35%), Gaps = 94/415 (22%)

Query: 786  PASLRFDGSPGQMGGGGPLRFEGPQGQLGG-GCPLRFEGPPGPV------GTPLRFEGPI 838
            P + RF     + G GG    EGP     G G   R E   GP        +     GP 
Sbjct: 322  PTADRFQAE--EYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPR 379

Query: 839  GQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQP 898
            G  G  G      PG+  EG PG    EGP G  +G    +G+ G PVG     GP G+ 
Sbjct: 380  GLKGEKGEPAVLEPGMLVEGPPGP---EGPAGL-IGPPGIQGNPG-PVGDPGERGPPGR- 433

Query: 899  VGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEG 958
                      G P      +G  GP G ++      G  GG    +GP+           
Sbjct: 434  ---------AGLPGS----DGAPGPPGTSLMLPFRFGSGGGD---KGPV----------- 466

Query: 959  PHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGG-GMRFE----GPSV 1013
                 VA    + Q       L   GP G  G   R  GPL Q G  G++ E    GP  
Sbjct: 467  -----VAAQEAQAQAILQQARLALRGPPGPMGYTGR-PGPLGQPGSPGLKGESGDLGPQG 520

Query: 1014 PGGGLRIEGPLGQGGPRFE-GCHALRFDGQPGQPSLL--PRFDGLHGQPGPRFERTPGQP 1070
            P G   + GP G+ G R   G    R  G PG P +     FDGL G PG +  R  G  
Sbjct: 521  PRGPQGLTGPPGKAGRRGRAGADGAR--GMPGDPGVKGDRGFDGLPGLPGEKGHR--GDT 576

Query: 1071 GPQRFDGPPGQQVQPRFDGV-----------PQRFDGPQHQQASRFDIPLGLQGTRFDNH 1119
            G Q   GPPG+  +   DG            P+   GP+         P G++G      
Sbjct: 577  GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPG--IPGPPGVRGMDGPQG 634

Query: 1120 PSQRLESVSFNQTGPYND--PPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHG 1172
            P   L        GP  +  PPG      +QGL           PQG    GPHG
Sbjct: 635  PKGSL--------GPQGEPGPPGQQGTPGTQGL---------PGPQGA--IGPHG 670



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 32/88 (36%), Positives = 36/88 (40%), Gaps = 9/88 (10%)

Query: 782  GPPTPASLRFDGSP-GQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP-IG 839
            GP  P  L     P G  G  GP    GP+G+ G   P    GPPG V  PL  + P   
Sbjct: 1456 GPGGPPGLPGPAGPKGAKGATGP---GGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKT 1512

Query: 840  QAGGGGFRF----EGSPGLRFEGSPGGL 863
            +    G R     E  P     GSPGGL
Sbjct: 1513 RRSVDGSRLMQEDEAIPTGGAPGSPGGL 1540


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  100 bits (250), Expect = 8e-21
 Identities = 110/336 (32%), Positives = 132/336 (39%), Gaps = 79/336 (23%)

Query: 791  FDGSPGQMGGGGPLRFEGPQGQLGG-GCPLR--FEGPPGPVGTPLRFEGPIGQAGGGGFR 847
            + G PG  G  G + F G  G  G  G P R    G PGP GTP    G IGQ G  G  
Sbjct: 475  YRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTP----GLIGQPGAKGEP 530

Query: 848  FEGSPGLRFEGSPGGLRFEGPGGQP--VGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFD 905
             E    LR +G  G   F G  G     G    +GH G P       GP G P G +   
Sbjct: 531  GEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLP-------GPKGSP-GSVGLK 582

Query: 906  NPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVA 965
              RG P GG+ F G  G +G       P G PG G    GP+  +G      GP      
Sbjct: 583  GERGPP-GGVGFPGSRGDTG-------PPGPPGYGPA--GPIGDKGQAGFPGGP------ 626

Query: 966  GLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLG 1025
                        G+    GP G+PG  +   GP   +G       P  PG      GP G
Sbjct: 627  ------------GSPGLPGPKGEPGKIVPLPGPPGAEGL------PGSPG----FPGPQG 664

Query: 1026 QGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFD------GPP 1079
              G          F G PG+P L P   G  GQPG  F   PG PGP+  D      GPP
Sbjct: 665  DRG----------FPGTPGRPGL-PGEKGAVGQPGIGF---PGPPGPKGVDGLPGDMGPP 710

Query: 1080 GQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTR 1115
            G   +P F+G+P    G    Q  + +  +GL G +
Sbjct: 711  GTPGRPGFNGLP----GNPGVQGQKGEPGVGLPGLK 742



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 133/424 (31%), Positives = 158/424 (37%), Gaps = 90/424 (21%)

Query: 777  SPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEG 836
            SP + G  +P S+ + GSPG  G  G     G  G  G        G PGP G P   +G
Sbjct: 1095 SPGLKG--SPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTG-PAGQKG 1151

Query: 837  PIGQAGGGGFRFE-GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP-----VGGLR 890
              G  G  G   E G PGL   G PG    +G  G   G + F G  G P      G   
Sbjct: 1152 EPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSK-GEVGFPGLAGSPGIPGSKGEQG 1210

Query: 891  FEGPHGQPVGGLRFDNPRGQPVGGLRFEGGH---GPSGAAIRFDGPHGQPG-GGIRFEGP 946
            F GP G          P+GQP  GL    GH   GP G      GP GQPG  G+   GP
Sbjct: 1211 FMGPPG----------PQGQP--GLPGSPGHATEGPKGDR----GPQGQPGLPGL--PGP 1252

Query: 947  LLQQGVGMRFEGPHG-QSVAGLRFEGQHNQLGGNLRFEGPHGQPGV----GIRFEGPLVQ 1001
            +          GP G   + G++ +  +    G     GP G PG     GI     +  
Sbjct: 1253 M----------GPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITG 1302

Query: 1002 QGGGM------RFEGPSVPGGGLRIEGPLG-QGGPRFEGCHALRFDGQPGQPSLLPRFDG 1054
              G M       F+GP    G   I+G  G QG P  +G       G PG P       G
Sbjct: 1303 SKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKG-----LPGPPGPPGPYDIIKG 1357

Query: 1055 LHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGT 1114
              G PGP  E  PG  G Q   GP GQQ      G+P                P G+ G 
Sbjct: 1358 EPGLPGP--EGPPGLKGLQGLPGPKGQQGVTGLVGIPG---------------PPGIPG- 1399

Query: 1115 RFDNHPSQRLESVSFNQTGP--YNDPPG-----NAFNAP-----SQGLQFQRHEQIFDSP 1162
             FD  P Q+ E      TGP  +  PPG      +   P       G    RH Q  D P
Sbjct: 1400 -FDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTIDDP 1458

Query: 1163 QGPN 1166
            Q P+
Sbjct: 1459 QCPS 1462



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 112/347 (32%), Positives = 141/347 (40%), Gaps = 53/347 (15%)

Query: 781  DGPPTPASLRFD----GSPGQMGGGGPLRFEGPQGQLG-GGCPLRFEGPPGPVGTP---- 831
            +GP  P   + D    G PG  G  GP    G  G  G  G P + +GPPGP G P    
Sbjct: 69   EGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQ-DGPPGPPGIPGCNG 127

Query: 832  -LRFEGPIGQAGGGGFRFE-GSPGLR-FEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGG 888
                 GP+G  G  GF    G PGL   +G PG +    PG    G   F G  G P G 
Sbjct: 128  TKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTP-GP 186

Query: 889  LRFEGPHGQPVGGLRFDNPRGQPVG----------GLRFEGGHGPSGAAIRFDGPHGQPG 938
                G  G PVG   F  P G P            GL F+G  G  G      GP G PG
Sbjct: 187  PGLPGLQG-PVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQ-GVSGPPGVPG 244

Query: 939  GG-IRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLG--------------GNLRFE 983
               ++ +G    +G   +   P  Q + G+  +G+  + G              G+  F 
Sbjct: 245  QAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFP 304

Query: 984  GPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPR-FEGCHALRFDGQ 1042
            G  G PG+ I  +GP  ++G      GP  P G +   GPLG+ G R + G    R  G+
Sbjct: 305  GEPGYPGL-IGRQGPQGEKGEA----GPPGPPGIVIGTGPLGEKGERGYPGTPGPR--GE 357

Query: 1043 PGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDG 1089
            PG       F GL GQPGP     PGQ G   F G  G++    F G
Sbjct: 358  PGPKG----FPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPG 400



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 135/465 (29%), Positives = 162/465 (34%), Gaps = 98/465 (21%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP----LR 833
            P I G P P  L     PG  G  GP  F GP G           GPPGP G      L 
Sbjct: 178  PGIPGTPGPPGL-----PGLQGPVGPPGFTGPPGP---------PGPPGPPGEKGQMGLS 223

Query: 834  FEGPIGQAGGGGFR------------------------------FEGSPGLRFEGSPGGL 863
            F+GP G  G  G                                F+G PG+  +G PG  
Sbjct: 224  FQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGK- 282

Query: 864  RFEGPGGQP--------VGGLRFEGHRGQPVGGLRFEGPHGQ--------PVGGLRFDNP 907
               GP G+P         G   F G  G P G +  +GP G+        P G +    P
Sbjct: 283  --PGPRGKPGKDGDKGEKGSPGFPGEPGYP-GLIGRQGPQGEKGEAGPPGPPGIVIGTGP 339

Query: 908  RGQPVGGLRFEGGHGPSG--AAIRFDGPHGQPG-GGIRFEGPLLQQGV-GMRFE-GPHGQ 962
             G+  G   + G  GP G      F G  GQPG  G+   G     G  G R E G  G 
Sbjct: 340  LGEK-GERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGF 398

Query: 963  SVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEG 1022
                L      + L G     GP GQPG      G +  Q G    +GP    G     G
Sbjct: 399  PGTSLPGPSGRDGLPGPPGSPGPPGQPGY---TNGIVECQPGPPGDQGPPGIPGQPGFIG 455

Query: 1023 PLGQGGPRFEGCHALRFDGQPGQPSLL--PRFDGLHGQPGPRFERTPGQPGPQRFDGPPG 1080
             +G+ G + E C     DG  G P     P   G  GQPG + +R  G PG     G PG
Sbjct: 456  EIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDR--GLPGRDGVAGVPG 513

Query: 1081 QQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFD-NHPSQRLESVSFNQTGPYNDP- 1138
             Q  P   G P     P       F   L L+G + D   P Q   +      G    P 
Sbjct: 514  PQGTPGLIGQPGAKGEP-----GEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPG 568

Query: 1139 -PGNAFNAPSQGLQFQR---------HEQIFDSPQGPNFNGPHGP 1173
             PG   +  S GL+ +R           +    P GP   GP GP
Sbjct: 569  LPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGP 613



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 120/383 (31%), Positives = 144/383 (37%), Gaps = 72/383 (18%)

Query: 754  GPSRPSVARDGPTKMIFEGP--NKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQG 811
            GP+ P+  +  P      G    K  P + G   P    F G+ G  G  G + F G  G
Sbjct: 1142 GPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPG---FPGAKGDKGSKGEVGFPGLAG 1198

Query: 812  QLG---GGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRF-EGSPGGLRFEG 867
              G         F GPPGP G P       G  G  G   EG  G R  +G PG     G
Sbjct: 1199 SPGIPGSKGEQGFMGPPGPQGQP-------GLPGSPGHATEGPKGDRGPQGQPGLPGLPG 1251

Query: 868  PGGQP----VGGLRFEGHRGQP--VGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGH 921
            P G P    + G++  G +G P   G     GP G P  G +     G   G    +G  
Sbjct: 1252 PMGPPGLPGIDGVK--GDKGNPGWPGAPGVPGPKGDP--GFQGMPGIGGSPGITGSKGDM 1307

Query: 922  GPSGAAIRFDGPHGQPG-GGIRFEGPLLQQGV--GMRFEGPHGQSVAGLRFEGQHNQLGG 978
            GP G    F GP G PG  GI+  G    QGV       GP G         G ++ + G
Sbjct: 1308 GPPGVP-GFQGPKGLPGLQGIK--GDQGDQGVPGAKGLPGPPGP-------PGPYDIIKG 1357

Query: 979  NLRFEGPHGQPGV-GIR-FEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHA 1036
                 GP G PG+ G++   GP  QQG            G + I GP G  G        
Sbjct: 1358 EPGLPGPEGPPGLKGLQGLPGPKGQQG----------VTGLVGIPGPPGIPG-------- 1399

Query: 1037 LRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDG 1096
              FDG PGQ   +    G  G  GPR    PG PGP   DG PG    P    V   F  
Sbjct: 1400 --FDGAPGQKGEM----GPAGPTGPR--GFPGPPGP---DGLPGSMGPPGTPSVDHGFLV 1448

Query: 1097 PQHQQASRFDIPLGLQGTRFDNH 1119
             +H Q    D P    GT+   H
Sbjct: 1449 TRHSQT--IDDPQCPSGTKILYH 1469



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 115/384 (29%), Positives = 142/384 (36%), Gaps = 87/384 (22%)

Query: 793  GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE--- 849
            G PGQ G  G   F G +G++G        G PGPVG P    G  G+ G  GF      
Sbjct: 861  GLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAP----GLPGEKGDHGFPGSSGP 916

Query: 850  -GSPGLRFE-------GSPGGLRF------------EGPGGQPVGGLRFEGHRGQP---- 885
             G PGL+ +       G PG +              +G  GQ +G +  +G RG P    
Sbjct: 917  RGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQ-IGPIGEKGSRGDPGTPG 975

Query: 886  -------VGGLRFEGPHGQP-----VGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGP 933
                    G     GP G P      G      P+G  VGG+   G  G  G      GP
Sbjct: 976  VPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGS-VGGMGLPGTPGEKGVP-GIPGP 1033

Query: 934  HGQPG-----GGIRFEGPLLQQGVGMR-FEGPHG-QSVAGLRFEGQHNQLG--GNLRFEG 984
             G PG     G    +G     G+G+    G  G Q +AG  F G   + G  G++   G
Sbjct: 1034 QGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAG--FPGSPGEKGEKGSIGIPG 1091

Query: 985  PHGQPG-------VGIRFEGPLVQQGGGMRFEG----PSVPG-----GGLRIEGPLGQGG 1028
              G PG       VG      L  + G     G    P V G     G     GP GQ G
Sbjct: 1092 MPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKG 1151

Query: 1029 -PRFEGCHALRFD-GQPGQPSL-LPRFDGLHGQPGPRFE----------RTPGQPGPQRF 1075
             P  +G      + G+PG P    P F G  G  G + E            PG  G Q F
Sbjct: 1152 EPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGF 1211

Query: 1076 DGPPGQQVQPRFDGVP-QRFDGPQ 1098
             GPPG Q QP   G P    +GP+
Sbjct: 1212 MGPPGPQGQPGLPGSPGHATEGPK 1235



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 127/418 (30%), Positives = 155/418 (37%), Gaps = 76/418 (18%)

Query: 783  PPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAG 842
            P  P      G PG  G  G +   G  GQ          G PGPVG P    G  G+ G
Sbjct: 860  PGLPGQQGAPGIPGFPGSKGEMGVMGTPGQ---------PGSPGPVGAP----GLPGEKG 906

Query: 843  GGGFRF----EGSPGLRFEGSPGGLRFEG-PG-------GQPVGGLRFEGHRGQ--PVGG 888
              GF       G PGL+  G  G +   G PG       G   G    +G +GQ  P+G 
Sbjct: 907  DHGFPGSSGPRGDPGLK--GDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGE 964

Query: 889  LRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLL 948
                G  G P G    D   GQP       G  GP G      G  G PG      GP  
Sbjct: 965  KGSRGDPGTP-GVPGKDGQAGQP-------GQPGPKGDP-GISGTPGAPG----LPGPKG 1011

Query: 949  QQGVGMRFEGPHGQ-SVAGLRFEGQHNQLGGNLRFEGPHGQ---PGVGI-RFEGPLVQQG 1003
              G GM   G  G+  V G+        L G+   +G  GQ   PG+GI    G    QG
Sbjct: 1012 SVG-GMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQG 1070

Query: 1004 GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGC-HALRFDGQPGQPSL-----LPRFDGLHG 1057
                   P   G    I  P   G P  +G   ++ + G PG P       LP  DG+ G
Sbjct: 1071 IAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPG 1130

Query: 1058 QPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFD 1117
              G      PG PGP    GP GQ+ +P  DG+P    G   ++        GL G  F 
Sbjct: 1131 VKGE--AGLPGTPGP---TGPAGQKGEPGSDGIP----GSAGEKGEP-----GLPGRGFP 1176

Query: 1118 NHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGN 1175
              P  + +  S  + G     PG    A S G+   + EQ F  P GP    P  PG+
Sbjct: 1177 GFPGAKGDKGSKGEVG----FPG---LAGSPGIPGSKGEQGFMGPPGPQ-GQPGLPGS 1226



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 137/484 (28%), Positives = 175/484 (36%), Gaps = 105/484 (21%)

Query: 749  RPLFDG-PSRPSV-ARDGPTKMIFEGPNKLSPRIDG-PPTPASLRFDGSPGQMGGGGPLR 805
            RP F+G P  P V  + G   +   G   L P + G P TP      G PG  G  G + 
Sbjct: 715  RPGFNGLPGNPGVQGQKGEPGVGLPGLKGL-PGLPGIPGTPGEKGSIGVPGVPGEHGAI- 772

Query: 806  FEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRF 865
              GP G  G        G PGP G P    G +G  G  G    G PG R  G PGG   
Sbjct: 773  --GPPGLQG------IRGEPGPPGLP----GSVGSPGVPGI---GPPGAR--GPPGG--- 812

Query: 866  EGPGGQPVGGLRFEGHRGQP-VGGLRFEGPHG----QPVGGLRFDN-----PRGQPVGGL 915
            +GP G   G    +G +G P   GL   GP G    Q + G+   +     P  Q   G+
Sbjct: 813  QGPPGLS-GPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGI 871

Query: 916  -RFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHN 974
              F G  G  G      G  GQPG      GP+   G+    +G HG       F G   
Sbjct: 872  PGFPGSKGEMGVM----GTPGQPGS----PGPVGAPGLPGE-KGDHG-------FPGSSG 915

Query: 975  QLG-----GNLRFEGPHGQPGVGIRFE-GPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGG 1028
              G     G+    G  G+PG   + + G +  Q G    +G   P G     G  G  G
Sbjct: 916  PRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPG 975

Query: 1029 PRFEGCHALRFDGQPGQPSLLPRFD-------GLHGQPGPRFE----RTPGQPGPQRFDG 1077
               +   A    GQPGQP   P+ D       G  G PGP+        PG PG +   G
Sbjct: 976  VPGKDGQA----GQPGQPG--PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPG 1029

Query: 1078 PPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTR----------FDNHPSQRLESV 1127
             PG Q  P   G      G + ++       +G+ G R          F   P ++ E  
Sbjct: 1030 IPGPQGSPGLPG----DKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKG 1085

Query: 1128 SFNQTGPYNDP-----PGNAFNAPSQGLQFQRHEQIFDSPQG----------PNFNGPHG 1172
            S    G    P     PG+     S GL  ++ ++      G          P   GP G
Sbjct: 1086 SIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTG 1145

Query: 1173 PGNQ 1176
            P  Q
Sbjct: 1146 PAGQ 1149



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 67/228 (29%), Positives = 74/228 (32%), Gaps = 66/228 (28%)

Query: 908  RGQP--VGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVA 965
            RG P   G + F G  GP       +GP G PG       P L    G R  GP G S  
Sbjct: 51   RGLPGLQGVIGFPGMQGP-------EGPQGPPGQKGDTGEPGLPGTKGTR--GPPGAS-- 99

Query: 966  GLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPG--GGLRIEGP 1023
                        GN    G  GQ G      GP            P +PG  G     GP
Sbjct: 100  ---------GYPGNPGLPGIPGQDGP----PGP------------PGIPGCNGTKGERGP 134

Query: 1024 LGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGP--------------RFERTPGQ 1069
            LG   P   G     F G PG P L     G+ G PG                F   PG 
Sbjct: 135  LGP--PGLPG-----FAGNPGPPGL----PGMKGDPGEILGHVPGMLLKGERGFPGIPGT 183

Query: 1070 PGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFD 1117
            PGP    G  G    P F G P    GP      +  + L  QG + D
Sbjct: 184  PGPPGLPGLQGPVGPPGFTGPPGP-PGPPGPPGEKGQMGLSFQGPKGD 230



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 48/169 (28%), Positives = 63/169 (37%), Gaps = 26/169 (15%)

Query: 1034 CHALRFD-GQPGQPSL-----LPRFDGLHGQPGPRFER----TPGQPGPQRFDGPPGQQV 1083
            CH ++   G+ G P L      P   G  G  GP  ++     PG PG +   GPPG   
Sbjct: 41   CHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASG 100

Query: 1084 QPRFDGVP--QRFDGPQHQQASRFDIPLGLQGTRFDNHP--SQRLESVSFNQ-----TGP 1134
             P   G+P     DGP         IP G  GT+ +  P     L   + N       G 
Sbjct: 101  YPGNPGLPGIPGQDGPPGPPG----IP-GCNGTKGERGPLGPPGLPGFAGNPGPPGLPGM 155

Query: 1135 YNDPPGNAFNAPSQGLQFQR-HEQIFDSPQGPNFNGPHGP-GNQSFSNP 1181
              DP     + P   L+ +R    I  +P  P   G  GP G   F+ P
Sbjct: 156  KGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGP 204


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  100 bits (250), Expect = 8e-21
 Identities = 125/371 (33%), Positives = 155/371 (41%), Gaps = 64/371 (17%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P + GPP P  L   G PG  G      F GPQG LG        GP GP+G P   +GP
Sbjct: 257  PGMHGPPGPVGLPGVGKPGVTG------FPGPQGPLGKPGAPGEPGPQGPIGVP-GVQGP 309

Query: 838  IGQAGGGGFRFEGSPGLRFEGSPGGLRFEG-------PGGQPVGGLRFEGHRG-QPVGGL 889
             G  G G    +G PG    G PGG   +G       PG   +G   F G +G + +GG+
Sbjct: 310  PGIPGIGKPGQDGIPGQ--PGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGV 367

Query: 890  RFE-GPHGQ--PVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGP 946
                GP G+  P+G      P G+P G     G  GP G AI F GP G+ GG +  +GP
Sbjct: 368  PGALGPRGEKGPIGAPGIGGPPGEP-GLPGIPGPMGPPG-AIGFPGPKGE-GGIVGPQGP 424

Query: 947  LLQQG-VGMR-FEGPHG----QSVAGLRF-------EGQHNQLG-----GNLRFEGPHGQ 988
               +G  G++ F G  G        G+R        +G+  Q G     G     GP G+
Sbjct: 425  PGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGE 484

Query: 989  PGV--GIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQP 1046
            PG+      +GP    G G    GPS P G   I GP G+ G            G PG P
Sbjct: 485  PGIPGDQGLQGPPGIPGIG----GPSGPIGPPGIPGPKGEPG----------LPGPPGFP 530

Query: 1047 SL-LPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRF-DGPQHQQASR 1104
             +  P   GLHG PG      PG  GPQ   G PG    P   G P      P  Q    
Sbjct: 531  GIGKPGVAGLHGPPG-----KPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYL 585

Query: 1105 FDIPLGLQGTR 1115
             D+ LG+ G +
Sbjct: 586  PDMGLGIDGVK 596



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 135/405 (33%), Positives = 158/405 (39%), Gaps = 95/405 (23%)

Query: 787  ASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGF 846
            ASLR  G  G  G  GP    GP G  G G P   +G PGP G P      +G+ G  G 
Sbjct: 114  ASLR--GEQGPRGEPGPRGPPGPPGLPGHGIP-GIKGKPGPQGYP-----GVGKPGMPG- 164

Query: 847  RFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDN 906
               G PG    G PG     G  G+ +G +   G +G P       GPHG P  G+    
Sbjct: 165  -MPGKPGAM--GMPGAKGEIGQKGE-IGPMGIPGPQGPP-------GPHGLP--GI---- 207

Query: 907  PRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG-GGIRFEGPLLQQGVGMRFEGPHGQSVA 965
              G+P GG    G  GP G      GP G PG  G+R  GP   +G GM    P    V 
Sbjct: 208  --GKP-GGPGLPGQPGPKGDR----GPKGLPGPQGLR--GPKGDKGFGM----PGAPGVK 254

Query: 966  GLRFEGQHNQLGGNLRFEGPHGQPGVG----IRFEGPLVQQGGGMRFEGPSVPGGGLRIE 1021
            G    G H          GP G PGVG      F GP   QG   +   P  PG     +
Sbjct: 255  GP--PGMHGP-------PGPVGLPGVGKPGVTGFPGP---QGPLGKPGAPGEPGP----Q 298

Query: 1022 GPLG----QGGPRFEGCHALRFDGQPGQPSLL--PRFDGLHGQPGPRFERTPGQPGPQRF 1075
            GP+G    QG P   G      DG PGQP         GL G PGP     PG PG  + 
Sbjct: 299  GPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGP-----PGLPGIGK- 352

Query: 1076 DGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQ-RLESVSFNQTGP 1134
             G PG +      GVP    GP+ ++      P+G  G      P +  L  +     GP
Sbjct: 353  PGFPGPKGDRGMGGVPGAL-GPRGEKG-----PIGAPG--IGGPPGEPGLPGI----PGP 400

Query: 1135 YNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHG-PGNQSF 1178
               P    F  P       + E     PQGP   GP G PG Q F
Sbjct: 401  MGPPGAIGFPGP-------KGEGGIVGPQGP--PGPKGEPGLQGF 436



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 123/390 (31%), Positives = 146/390 (37%), Gaps = 91/390 (23%)

Query: 778  PRIDGPPTPASLR------FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGT- 830
            P I G P P            G PG+ G  G    +G  GQ G   P+   GP GP G  
Sbjct: 143  PGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPH 202

Query: 831  ------------------------PLRFEGP---IGQAGGGGFRFEGSPGLRFE------ 857
                                    P    GP    G  G  GF   G+PG++        
Sbjct: 203  GLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGP 262

Query: 858  ---------GSPGGLRFEGPGGQPVGGLRFEGHRGQ--PVGGLRFEGPHGQP-VGGLRFD 905
                     G PG   F GP G P+G     G  G   P+G    +GP G P +G    D
Sbjct: 263  PGPVGLPGVGKPGVTGFPGPQG-PLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQD 321

Query: 906  NPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG-GGIRFEGPLLQQGVGMRFEGPHGQSV 964
               GQP     F GG G  G      GP G PG G   F GP   +G+G    G  G   
Sbjct: 322  GIPGQP----GFPGGKGEQGLP-GLPGPPGLPGIGKPGFPGPKGDRGMG----GVPG--- 369

Query: 965  AGLRFEGQHNQLGGNLRFEGPHGQPGV-GIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGP 1023
              L   G+   +G      GP G+PG+ GI   GP+    G + F GP   GG   I GP
Sbjct: 370  -ALGPRGEKGPIGAP-GIGGPPGEPGLPGI--PGPM-GPPGAIGFPGPKGEGG---IVGP 421

Query: 1024 LGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQV 1083
             G  GP+ E        G PG+P  L    G  G PG R     G PGP    G  GQ+ 
Sbjct: 422  QGPPGPKGEP----GLQGFPGKPGFL----GEVGPPGMR-----GLPGPIGPKGEAGQKG 468

Query: 1084 QPRFDGVPQRFDGPQHQQASRFDIPLGLQG 1113
             P   GVP    GP+ +     D   GLQG
Sbjct: 469  VPGLPGVPGLL-GPKGEPGIPGD--QGLQG 495



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 75/239 (31%), Positives = 95/239 (39%), Gaps = 51/239 (21%)

Query: 885  PVGGLRFE-GPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRF 943
            P+  LR E GP G+P        PRG P  G     GHG  G   +  GP G PG G   
Sbjct: 112  PLASLRGEQGPRGEP-------GPRGPP--GPPGLPGHGIPGIKGK-PGPQGYPGVG--- 158

Query: 944  EGPLLQQGVGMRFEGPHGQSVAGLRFE-GQHNQLG-----GNLRFEGPHGQPGVGIRFEG 997
                 + G+      P    + G + E GQ  ++G     G     GPHG PG+G     
Sbjct: 159  -----KPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIG----- 208

Query: 998  PLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPR-FEGCHALRFDGQPGQPSLLPRFDGLH 1056
                + GG    G   P G     GP G  GP+   G    +  G PG P +     G+H
Sbjct: 209  ----KPGGPGLPGQPGPKGD---RGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGP-PGMH 260

Query: 1057 GQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTR 1115
            G PGP      G+PG   F GP G   +P   G P    GPQ         P+G+ G +
Sbjct: 261  GPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEP----GPQG--------PIGVPGVQ 307



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 52/157 (33%), Positives = 61/157 (38%), Gaps = 20/157 (12%)

Query: 783 PPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAG 842
           P  P  L   G PG  G  G    +GP G  G G P    GPPG         GP G+ G
Sbjct: 473 PGVPGLLGPKGEPGIPGDQG---LQGPPGIPGIGGPSGPIGPPG-------IPGPKGEPG 522

Query: 843 GGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGL 902
                  G PG    G PG     GP G+P G L  +G  G P G     GP G P    
Sbjct: 523 -----LPGPPGFPGIGKPGVAGLHGPPGKP-GALGPQGQPGLP-GPPGPPGPPGPPAVMP 575

Query: 903 RFDNPRGQ--PVGGLRFEGGHGPSGAAIRFDGPHGQP 937
               P+G+  P  GL  +G   P     +  G +G P
Sbjct: 576 PTPPPQGEYLPDMGLGIDGVKPPHAYGAK-KGKNGGP 611



 Score = 35.8 bits (81), Expect = 0.33
 Identities = 32/82 (39%), Positives = 35/82 (42%), Gaps = 10/82 (12%)

Query: 750 PLFDGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGP 809
           P   GPS P     GP  +   GP K  P + GPP    +   G  G  G  G     GP
Sbjct: 500 PGIGGPSGPI----GPPGI--PGP-KGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGP 552

Query: 810 QGQLGGGCPLRFEGPPGPVGTP 831
           QGQ G   P    GPPGP G P
Sbjct: 553 QGQPGLPGP---PGPPGPPGPP 571


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  100 bits (250), Expect = 8e-21
 Identities = 125/371 (33%), Positives = 155/371 (41%), Gaps = 64/371 (17%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P + GPP P  L   G PG  G      F GPQG LG        GP GP+G P   +GP
Sbjct: 257  PGMHGPPGPVGLPGVGKPGVTG------FPGPQGPLGKPGAPGEPGPQGPIGVP-GVQGP 309

Query: 838  IGQAGGGGFRFEGSPGLRFEGSPGGLRFEG-------PGGQPVGGLRFEGHRG-QPVGGL 889
             G  G G    +G PG    G PGG   +G       PG   +G   F G +G + +GG+
Sbjct: 310  PGIPGIGKPGQDGIPGQ--PGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGV 367

Query: 890  RFE-GPHGQ--PVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGP 946
                GP G+  P+G      P G+P G     G  GP G AI F GP G+ GG +  +GP
Sbjct: 368  PGALGPRGEKGPIGAPGIGGPPGEP-GLPGIPGPMGPPG-AIGFPGPKGE-GGIVGPQGP 424

Query: 947  LLQQG-VGMR-FEGPHG----QSVAGLRF-------EGQHNQLG-----GNLRFEGPHGQ 988
               +G  G++ F G  G        G+R        +G+  Q G     G     GP G+
Sbjct: 425  PGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGE 484

Query: 989  PGV--GIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQP 1046
            PG+      +GP    G G    GPS P G   I GP G+ G            G PG P
Sbjct: 485  PGIPGDQGLQGPPGIPGIG----GPSGPIGPPGIPGPKGEPG----------LPGPPGFP 530

Query: 1047 SL-LPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRF-DGPQHQQASR 1104
             +  P   GLHG PG      PG  GPQ   G PG    P   G P      P  Q    
Sbjct: 531  GIGKPGVAGLHGPPG-----KPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYL 585

Query: 1105 FDIPLGLQGTR 1115
             D+ LG+ G +
Sbjct: 586  PDMGLGIDGVK 596



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 135/405 (33%), Positives = 158/405 (39%), Gaps = 95/405 (23%)

Query: 787  ASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGF 846
            ASLR  G  G  G  GP    GP G  G G P   +G PGP G P      +G+ G  G 
Sbjct: 114  ASLR--GEQGPRGEPGPRGPPGPPGLPGHGIP-GIKGKPGPQGYP-----GVGKPGMPG- 164

Query: 847  RFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDN 906
               G PG    G PG     G  G+ +G +   G +G P       GPHG P  G+    
Sbjct: 165  -MPGKPGAM--GMPGAKGEIGQKGE-IGPMGIPGPQGPP-------GPHGLP--GI---- 207

Query: 907  PRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG-GGIRFEGPLLQQGVGMRFEGPHGQSVA 965
              G+P GG    G  GP G      GP G PG  G+R  GP   +G GM    P    V 
Sbjct: 208  --GKP-GGPGLPGQPGPKGDR----GPKGLPGPQGLR--GPKGDKGFGM----PGAPGVK 254

Query: 966  GLRFEGQHNQLGGNLRFEGPHGQPGVG----IRFEGPLVQQGGGMRFEGPSVPGGGLRIE 1021
            G    G H          GP G PGVG      F GP   QG   +   P  PG     +
Sbjct: 255  GP--PGMHGP-------PGPVGLPGVGKPGVTGFPGP---QGPLGKPGAPGEPGP----Q 298

Query: 1022 GPLG----QGGPRFEGCHALRFDGQPGQPSLL--PRFDGLHGQPGPRFERTPGQPGPQRF 1075
            GP+G    QG P   G      DG PGQP         GL G PGP     PG PG  + 
Sbjct: 299  GPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGP-----PGLPGIGK- 352

Query: 1076 DGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQ-RLESVSFNQTGP 1134
             G PG +      GVP    GP+ ++      P+G  G      P +  L  +     GP
Sbjct: 353  PGFPGPKGDRGMGGVPGAL-GPRGEKG-----PIGAPG--IGGPPGEPGLPGI----PGP 400

Query: 1135 YNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHG-PGNQSF 1178
               P    F  P       + E     PQGP   GP G PG Q F
Sbjct: 401  MGPPGAIGFPGP-------KGEGGIVGPQGP--PGPKGEPGLQGF 436



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 123/390 (31%), Positives = 146/390 (37%), Gaps = 91/390 (23%)

Query: 778  PRIDGPPTPASLR------FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGT- 830
            P I G P P            G PG+ G  G    +G  GQ G   P+   GP GP G  
Sbjct: 143  PGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPH 202

Query: 831  ------------------------PLRFEGP---IGQAGGGGFRFEGSPGLRFE------ 857
                                    P    GP    G  G  GF   G+PG++        
Sbjct: 203  GLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGP 262

Query: 858  ---------GSPGGLRFEGPGGQPVGGLRFEGHRGQ--PVGGLRFEGPHGQP-VGGLRFD 905
                     G PG   F GP G P+G     G  G   P+G    +GP G P +G    D
Sbjct: 263  PGPVGLPGVGKPGVTGFPGPQG-PLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQD 321

Query: 906  NPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG-GGIRFEGPLLQQGVGMRFEGPHGQSV 964
               GQP     F GG G  G      GP G PG G   F GP   +G+G    G  G   
Sbjct: 322  GIPGQP----GFPGGKGEQGLP-GLPGPPGLPGIGKPGFPGPKGDRGMG----GVPG--- 369

Query: 965  AGLRFEGQHNQLGGNLRFEGPHGQPGV-GIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGP 1023
              L   G+   +G      GP G+PG+ GI   GP+    G + F GP   GG   I GP
Sbjct: 370  -ALGPRGEKGPIGAP-GIGGPPGEPGLPGI--PGPM-GPPGAIGFPGPKGEGG---IVGP 421

Query: 1024 LGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQV 1083
             G  GP+ E        G PG+P  L    G  G PG R     G PGP    G  GQ+ 
Sbjct: 422  QGPPGPKGEP----GLQGFPGKPGFL----GEVGPPGMR-----GLPGPIGPKGEAGQKG 468

Query: 1084 QPRFDGVPQRFDGPQHQQASRFDIPLGLQG 1113
             P   GVP    GP+ +     D   GLQG
Sbjct: 469  VPGLPGVPGLL-GPKGEPGIPGD--QGLQG 495



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 75/239 (31%), Positives = 95/239 (39%), Gaps = 51/239 (21%)

Query: 885  PVGGLRFE-GPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRF 943
            P+  LR E GP G+P        PRG P  G     GHG  G   +  GP G PG G   
Sbjct: 112  PLASLRGEQGPRGEP-------GPRGPP--GPPGLPGHGIPGIKGK-PGPQGYPGVG--- 158

Query: 944  EGPLLQQGVGMRFEGPHGQSVAGLRFE-GQHNQLG-----GNLRFEGPHGQPGVGIRFEG 997
                 + G+      P    + G + E GQ  ++G     G     GPHG PG+G     
Sbjct: 159  -----KPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIG----- 208

Query: 998  PLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPR-FEGCHALRFDGQPGQPSLLPRFDGLH 1056
                + GG    G   P G     GP G  GP+   G    +  G PG P +     G+H
Sbjct: 209  ----KPGGPGLPGQPGPKGD---RGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGP-PGMH 260

Query: 1057 GQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTR 1115
            G PGP      G+PG   F GP G   +P   G P    GPQ         P+G+ G +
Sbjct: 261  GPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEP----GPQG--------PIGVPGVQ 307



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 52/157 (33%), Positives = 61/157 (38%), Gaps = 20/157 (12%)

Query: 783 PPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAG 842
           P  P  L   G PG  G  G    +GP G  G G P    GPPG         GP G+ G
Sbjct: 473 PGVPGLLGPKGEPGIPGDQG---LQGPPGIPGIGGPSGPIGPPG-------IPGPKGEPG 522

Query: 843 GGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGL 902
                  G PG    G PG     GP G+P G L  +G  G P G     GP G P    
Sbjct: 523 -----LPGPPGFPGIGKPGVAGLHGPPGKP-GALGPQGQPGLP-GPPGPPGPPGPPAVMP 575

Query: 903 RFDNPRGQ--PVGGLRFEGGHGPSGAAIRFDGPHGQP 937
               P+G+  P  GL  +G   P     +  G +G P
Sbjct: 576 PTPPPQGEYLPDMGLGIDGVKPPHAYGAK-KGKNGGP 611



 Score = 35.8 bits (81), Expect = 0.33
 Identities = 32/82 (39%), Positives = 35/82 (42%), Gaps = 10/82 (12%)

Query: 750 PLFDGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGP 809
           P   GPS P     GP  +   GP K  P + GPP    +   G  G  G  G     GP
Sbjct: 500 PGIGGPSGPI----GPPGI--PGP-KGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGP 552

Query: 810 QGQLGGGCPLRFEGPPGPVGTP 831
           QGQ G   P    GPPGP G P
Sbjct: 553 QGQPGLPGP---PGPPGPPGPP 571


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  100 bits (248), Expect = 1e-20
 Identities = 135/431 (31%), Positives = 159/431 (36%), Gaps = 92/431 (21%)

Query: 764  GPTKMIFE-GPNKL-SPRIDGPPT--PASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPL 819
            GPT    E GP  L  PR    PT  P     DG+PG  G  GP    GP GQ G     
Sbjct: 590  GPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQ 649

Query: 820  RFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFE 879
               GP G +GTP       G+ G       G+PG+   G PG    +GP G P       
Sbjct: 650  GLPGPQGLIGTP-------GEKGP-----PGNPGI--PGLPGS---DGPLGHP------- 685

Query: 880  GHRGQPVGGLRFEGPHGQPVGGLRFDNPRG----------QPVGGLRFEGGHGPSGAAIR 929
            GH G P G    +GP G   G   +  PRG          Q   G + E G       + 
Sbjct: 686  GHEG-PTGEKGAQGPPGS-AGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVG 743

Query: 930  FDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQP 989
              G  G+PG      GP  + G     EGP GQ+              G    EGP G  
Sbjct: 744  LKGDQGKPGA----PGPRGEDGP----EGPKGQA--------------GQAGEEGPPGSA 781

Query: 990  GVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLL 1049
            G   +   P     G   + G   P G +   GPLG  G + +        G+ GQP L 
Sbjct: 782  GEKGKLGVP-----GLPGYPGRPGPKGSIGFPGPLGPIGEKGK-------SGKTGQPGL- 828

Query: 1050 PRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPL 1109
               +G  G PG R ER  GQPG     GP G   Q    G+P     P  Q    F  P 
Sbjct: 829  ---EGERGPPGSRGER--GQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPK 883

Query: 1110 GLQGTRFDN----HPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
            G  G +  +    HP QR E     QTG    PPG A     QG   +        P GP
Sbjct: 884  GPPGHQGKDGRPGHPGQRGELGFQGQTG----PPGPAGVLGPQGKTGEVGPLGERGPPGP 939

Query: 1166 NFNGPHGPGNQ 1176
                P  PG Q
Sbjct: 940  ----PGPPGEQ 946



 Score = 91.3 bits (225), Expect = 7e-18
 Identities = 120/386 (31%), Positives = 145/386 (37%), Gaps = 101/386 (26%)

Query: 781  DGPPTPASLRFD-GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP-------- 831
            DG P     R + G  GQ G  GP    GPQG+ G   PL   GPPGP G P        
Sbjct: 892  DGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGL 951

Query: 832  ---------LRFEGPIGQAGGGGFR-FEGSPGLRFEGSPGGLRFE-GPGGQPVGGLRFEG 880
                     L   GP+G+ G  G R F G  G   +  P GL+ + GP G PVG     G
Sbjct: 952  EGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPG-PVGANGSPG 1010

Query: 881  HRGQ--PVGGLRFEGPHGQ--PVGGLRFDNPRGQ--------------PVGGLRFEGGHG 922
             RG   P GG+   G  G   PVG       RG+              P+G L   G  G
Sbjct: 1011 ERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAG 1070

Query: 923  PSG-------------AAIRFD----GPHGQPG--GGIRFEGPLLQQGVGMRFEGPHG-- 961
            PSG                + D    GP GQPG  G     GP    G   R  GP G  
Sbjct: 1071 PSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGR-RGPPGLF 1129

Query: 962  --QSVAGLR-------------FEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQGG 1004
              +   G+R               G   + G  G++   GPHG P       GP   QG 
Sbjct: 1130 GQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAP-------GPRGPQGP 1182

Query: 1005 GMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFE 1064
                  P +P GG+   G +G+ G R +        G PG P       G  G PGP+ +
Sbjct: 1183 TGSEGTPGLP-GGVGQPGAVGEKGERGDA-------GDPGPP-------GAPGIPGPKGD 1227

Query: 1065 -RTPGQPGPQRFDGPPGQQVQPRFDG 1089
                G  GP    GPPG++  P  DG
Sbjct: 1228 IGEKGDSGPSGAAGPPGKKGPPGEDG 1253



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 128/380 (33%), Positives = 154/380 (40%), Gaps = 89/380 (23%)

Query: 754  GPSRPSVARDGPTKMI-FEGPNKLSPRIDGPP-------TPASLRFDGSPGQMGGGGPLR 805
            GP  P + ++GP  +  F GP K  P   GP         P  +  +GSPG+ G  GP  
Sbjct: 962  GPPGP-LGKEGPAGLRGFPGP-KGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAG 1019

Query: 806  FEGPQGQLGGGCPL--------RFE-GPPGPVGT-----PLRFEGPIGQAGGGGFRFE-- 849
              G  GQ G   P+        R E GPPGP G      PL   GP G AG  G   +  
Sbjct: 1020 GIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKG 1079

Query: 850  --GSPGLRFEGSPGGLRFEGPGGQPVGGLRFE-GHRGQPVGGLRFEGPHGQP--VGGLRF 904
              G+PG   +GS G     GP GQP  G+R   GH G P G    +G  G P   G    
Sbjct: 1080 DVGAPG--HKGSKGDKGDAGPPGQP--GIRGPAGHPGPP-GADGAQGRRGPPGLFGQKGD 1134

Query: 905  DNPRG--QPVGGLRFEGGHGPSGAA-----IRFDGPHGQPG-----GGIRFEG-PLLQQG 951
            D  RG    +G    +G  GP G       +   GPHG PG     G    EG P L  G
Sbjct: 1135 DGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGG 1194

Query: 952  VGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGP 1011
            VG    G  G+       +G+    G      GP G PG+     GP     G +  +G 
Sbjct: 1195 VGQ--PGAVGE-------KGERGDAGD----PGPPGAPGI----PGPK----GDIGEKGD 1233

Query: 1012 SVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPG 1071
            S P G     GP G+ GP  E       DG  G  S+ P   GL G  GP     PG PG
Sbjct: 1234 SGPSGAA---GPPGKKGPPGE-------DGAKG--SVGPT--GLPGDLGP-----PGDPG 1274

Query: 1072 PQRFDGPPGQQVQPRFDGVP 1091
                DG PG++  P   G P
Sbjct: 1275 VSGIDGSPGEKGDPGDVGGP 1294



 Score = 84.7 bits (208), Expect = 6e-16
 Identities = 147/468 (31%), Positives = 178/468 (38%), Gaps = 85/468 (18%)

Query: 754  GPSRPSVARDGPTKMIFEGP-----NKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEG 808
            GP  P+     P +   EGP      K S    GPP P     DG PG +G  GP    G
Sbjct: 1013 GPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGK--DGIPGPLGPLGPPGAAG 1070

Query: 809  PQGQLGG----GCPLRF--------EGPPGPVGT--PLRFEGPIGQAGGGGFRFEGSPGL 854
            P G+ G     G P            GPPG  G   P    GP G  G  G R  G PGL
Sbjct: 1071 PSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRR--GPPGL 1128

Query: 855  RFEGSPGGLR-FEGPGGQPVGGLRF----EGHRGQPVGGLRFEGPHGQPVGGLRFDNPRG 909
              +    G+R F G  G P  GL+      G +G+ VG +   GPHG P G      P G
Sbjct: 1129 FGQKGDDGVRGFVGVIGPP--GLQGLPGPPGEKGE-VGDVGSMGPHGAP-GPRGPQGPTG 1184

Query: 910  QPVGGLRFEGGHGPSGAA----IRFD----GPHGQPG-----GGIRFEGPLLQQGVG--M 954
               G     GG G  GA      R D    GP G PG     G I  +G     G     
Sbjct: 1185 SE-GTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPP 1243

Query: 955  RFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVP 1014
              +GP G+   G +       L G+L   GP G PGV    +G   ++G      GP  P
Sbjct: 1244 GKKGPPGED--GAKGSVGPTGLPGDL---GPPGDPGVS-GIDGSPGEKGDPGDVGGPGPP 1297

Query: 1015 G--GGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGP 1072
            G  G     GP G+ GP     H  R +G+ G+        G  G+PGP  +  PG+ GP
Sbjct: 1298 GASGEPGAPGPPGKRGP---SGHMGR-EGREGEK-------GAKGEPGP--DGPPGRTGP 1344

Query: 1073 QRFDGPPGQQVQPRFDGVPQRFD-----GPQHQQASRFDI-PLGLQGTRFDNHPSQRLES 1126
                GPPG+       G+P         G   Q      + P GL G + D  P  + E 
Sbjct: 1345 MGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGP--KGEK 1402

Query: 1127 VSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFN-GPHGP 1173
                  G    PPG A     QGL           P GP  + GP GP
Sbjct: 1403 GHIGLIGLIG-PPGEAGEKGDQGLPG------VQGPPGPKGDPGPPGP 1443



 Score = 80.9 bits (198), Expect = 9e-15
 Identities = 104/308 (33%), Positives = 127/308 (41%), Gaps = 55/308 (17%)

Query: 805  RFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGG-- 862
            +FEGP G  G    +   GPPGP G P    GP G AG  G    G  G+R  G PG   
Sbjct: 389  QFEGPPGAPGPQGVVGPSGPPGPPGFP-GDPGPPGPAGLPG--IPGIDGIR--GPPGTVI 443

Query: 863  -LRFEGPGGQPVG-GLRFEGHRGQPV---GGLRFEGPHGQPVGGLRFDNPRGQP--VGGL 915
             + F+  GG   G  + F+  + Q V     L  +GP G PVG      P G P   G  
Sbjct: 444  MMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPG-PVGLTGRPGPVGLPGHPGLK 502

Query: 916  RFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFE-GPHG-QSVAGL-RFEGQ 972
              EG  GP G      GPHG PG   +   P      G+  + GP G +   GL    G+
Sbjct: 503  GEEGAEGPQGPR-GLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGE 561

Query: 973  HNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPR 1030
              Q G  G++   GP G+ G          ++G     EGP  P G     GP G  GPR
Sbjct: 562  KGQRGDFGHVGQPGPPGEDG----------ERGA----EGPPGPTGQAGEPGPRGLLGPR 607

Query: 1031 FEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGV 1090
                      G PG P+  P   G+ G PG +     G  GP    GPPGQQ      G+
Sbjct: 608  ----------GSPG-PTGRPGVTGIDGAPGAK-----GNVGPPGEPGPPGQQGNHGSQGL 651

Query: 1091 PQRFDGPQ 1098
            P    GPQ
Sbjct: 652  P----GPQ 655



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 112/360 (31%), Positives = 142/360 (39%), Gaps = 63/360 (17%)

Query: 782  GPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQA 841
            GPP    L   G PG+ G  G +   GP G  G   P   +GP G  GTP    G +GQ 
Sbjct: 1145 GPPGLQGL--PGPPGEKGEVGDVGSMGPHGAPGPRGP---QGPTGSEGTP-GLPGGVGQP 1198

Query: 842  GGGGFRFE----------GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPV--GGL 889
            G  G + E          G+PG+   G  G +  +G  G P G     G +G P   G  
Sbjct: 1199 GAVGEKGERGDAGDPGPPGAPGI--PGPKGDIGEKGDSG-PSGAAGPPGKKGPPGEDGAK 1255

Query: 890  RFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPL 947
               GP G P G L    P G P G    +G  G  G      GP G PG  G     GP 
Sbjct: 1256 GSVGPTGLP-GDL---GPPGDP-GVSGIDGSPGEKGDPGDVGGP-GPPGASGEPGAPGPP 1309

Query: 948  LQQGVG--MRFEGPHGQSVAGLRFEGQHNQLG-----GNLRFEGPHGQPGV-GIR-FEGP 998
             ++G    M  EG  G+  A    +G+    G     G +   GP G+ G  G+R   GP
Sbjct: 1310 GKRGPSGHMGREGREGEKGA----KGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGP 1365

Query: 999  LVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHA--LRFDGQPGQPSLL--PRF 1052
            + + G  G     GP  P G   + G  G  GP+ E  H   +   G PG+         
Sbjct: 1366 VGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGL 1425

Query: 1053 DGLHGQPGPRFERTP-------GQPGPQRFDGPPGQQ--------VQPRFDGVPQRFDGP 1097
             G+ G PGP+ +  P       G PGP    GP GQ+        + PR D  P    GP
Sbjct: 1426 PGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGP 1485



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 100/319 (31%), Positives = 118/319 (36%), Gaps = 63/319 (19%)

Query: 754  GPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQL 813
            G S PS A   P K    G +     +     P  L   G PG  G  G    +G  G +
Sbjct: 1232 GDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDV 1291

Query: 814  GGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPV 873
            GG  P    G PG  G P +  GP G  G  G   EG  G + E  P G         P 
Sbjct: 1292 GGPGPPGASGEPGAPGPPGK-RGPSGHMGREG--REGEKGAKGEPGPDG---------PP 1339

Query: 874  GGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGP 933
            G     G RG P G +  EG  G P        P G+P G L   G  GP G      GP
Sbjct: 1340 GRTGPMGARGPP-GRVGPEGLRGIP-------GPVGEP-GLLGAPGQMGPPGPL----GP 1386

Query: 934  HGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGI 993
             G PG         L+   G + E  H   +  +   G+  +       +G  G PGV  
Sbjct: 1387 SGLPG---------LKGDTGPKGEKGHIGLIGLIGPPGEAGE-------KGDQGLPGV-- 1428

Query: 994  RFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQP-SLLPRF 1052
              +GP   +G      GP  P G L   GP G  GP       L   G  G P S+ PR 
Sbjct: 1429 --QGPPGPKGD----PGPPGPIGSLGHPGPPGVAGP-------LGQKGSKGSPGSMGPRG 1475

Query: 1053 D-GLHGQPGPRFERTPGQP 1070
            D G  G PGP     PG P
Sbjct: 1476 DTGPAGPPGP-----PGAP 1489



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 50/175 (28%), Positives = 60/175 (34%), Gaps = 45/175 (25%)

Query: 1005 GMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFE 1064
            G +FEGP    G   + GP G  GP           G PG P          G PGP   
Sbjct: 387  GQQFEGPPGAPGPQGVVGPSGPPGP----------PGFPGDP----------GPPGP--A 424

Query: 1065 RTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRL 1124
              PG PG     GPPG  +   F      F GP          P+  Q  +        L
Sbjct: 425  GLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGP----------PVSFQQAQ----AQAVL 470

Query: 1125 ESVSFNQTGP-----YNDPPGNAFNAPSQGLQFQRHEQIFDSPQGP-NFNGPHGP 1173
            +    +  GP         PG        GL   + E+  + PQGP    GPHGP
Sbjct: 471  QQTQLSMKGPPGPVGLTGRPGPVGLPGHPGL---KGEEGAEGPQGPRGLQGPHGP 522


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 142/448 (31%), Positives = 171/448 (38%), Gaps = 89/448 (19%)

Query: 754  GPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQL 813
            G + P  A   P K   +G   L+  I GPP PA     G+PG  G  GP    GP G  
Sbjct: 746  GDAGPKGADGSPGK---DGVRGLTGPI-GPPGPA-----GAPGDKGESGPSGPAGPTGAR 796

Query: 814  GGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE-GSPGLRFEGSPGGLRFEGPGGQP 872
            G        GPPGP G    F GP G  G  G + E G  G + +  P G    GP G P
Sbjct: 797  GAPGDRGEPGPPGPAG----FAGPPGADGQPGAKGEPGDAGAKGDAGPPGP--AGPAGPP 850

Query: 873  -----VGGLRFEGHRGQ--PVGGLRFEGPHGQ--PVGGLRFDNPRGQPVGGLRFEGGHGP 923
                 VG    +G RG   P G   F G  G+  P G      P G P G    EGG GP
Sbjct: 851  GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP-GPAGKEGGKGP 909

Query: 924  SGAAIRFDGPHGQPG--GGIRFEGPLLQQGVGMRFEGPHG-------QSVAGLR----FE 970
             G      GP G+PG  G     GP  ++G     +GP G       Q +AG R      
Sbjct: 910  RGET----GPAGRPGEVGPPGPPGPAGEKG-SPGADGPAGAPGTPGPQGIAGQRGVVGLP 964

Query: 971  GQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPR 1030
            GQ  + G      GP G+PG     +GP     G     GP  P G   + GP G+ G  
Sbjct: 965  GQRGERGFP-GLPGPSGEPGK----QGP----SGASGERGPPGPMGPPGLAGPPGESGR- 1014

Query: 1031 FEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGP--PGQQVQPRFD 1088
             EG  A   +G PG+    P   G  G+ GP     PG PG     GP  P  +   R +
Sbjct: 1015 -EG--APGAEGSPGRDG-SPGAKGDRGETGP--AGPPGAPGAPGAPGPVGPAGKSGDRGE 1068

Query: 1089 GVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQ 1148
              P    GP     +R   P G QG R D             +TG   D          +
Sbjct: 1069 TGPAGPAGPVGPVGARG--PAGPQGPRGDK-----------GETGEQGD----------R 1105

Query: 1149 GLQFQRHEQIFDSPQGPNFNGPHGPGNQ 1176
            G++  R       P GP    P  PG Q
Sbjct: 1106 GIKGHRGFSGLQGPPGP----PGSPGEQ 1129



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 112/343 (32%), Positives = 137/343 (39%), Gaps = 54/343 (15%)

Query: 780  IDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLG---GGCPLRFEGPPGPVGTPLRFEG 836
            + GP  P+  R  G PG  G  GP  F+GP G+ G      P+   GPPGP G      G
Sbjct: 177  VPGPMGPSGPR--GLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK----NG 230

Query: 837  PIGQAGGGGFRFEGSPGLRFEGSPGGLR-FEGPGGQPVGGLRFEGHRG-QPVGGLRFE-- 892
              G+AG       G PG R    P G R   G  G P      +GHRG   + G + +  
Sbjct: 231  DDGEAGK-----PGRPGERGPPGPQGARGLPGTAGLP----GMKGHRGFSGLDGAKGDAG 281

Query: 893  --GPHGQP-----VGGLRFDNPRGQPVGGLRFEGGHGPSGA-----AIRFDGPHGQ--PG 938
              GP G+P      G      PRG P G     G  GP+GA     A    GP G   P 
Sbjct: 282  PAGPKGEPGSPGENGAPGQMGPRGLP-GERGRPGAPGPAGARGNDGATGAAGPPGPTGPA 340

Query: 939  GGIRFEGPLLQQGVGMRFEGPHG-QSVAGLRFE-GQHNQLG--GNLRFEGPHGQPGV-GI 993
            G   F G +  +G     +GP G +   G+R E G     G  G     G  GQPG  G 
Sbjct: 341  GPPGFPGAVGAKGEAGP-QGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGA 399

Query: 994  RFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFD-GQPGQPSLLPRF 1052
                 +    G     GPS P G     GP G  G    G    + D G  G+P  +   
Sbjct: 400  NGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE--PGAPGSKGDTGAKGEPGPV--- 454

Query: 1053 DGLHGQPGPRFER----TPGQPGPQRFDGPPGQQVQPRFDGVP 1091
             G+ G PGP  E       G+PGP    GPPG++  P   G P
Sbjct: 455  -GVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFP 496



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 112/334 (33%), Positives = 135/334 (40%), Gaps = 55/334 (16%)

Query: 782  GPPTP-ASLRFDGSPGQMGGGGP---LRFEGPQGQLGGGCPLRFEGPPGPVGTPLRF--E 835
            GPP P  ++   G+ G  G  GP     F G  G++G   P    GPPGP G   +   +
Sbjct: 848  GPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK 907

Query: 836  GPIGQAGGGGFRFE----GSPGLRFE-GSPGGLRFEGPGGQP--VGGLRFEGHRGQPVGG 888
            GP G+ G  G   E    G PG   E GSPG    +GP G P   G     G RG  VG 
Sbjct: 908  GPRGETGPAGRPGEVGPPGPPGPAGEKGSPGA---DGPAGAPGTPGPQGIAGQRGV-VGL 963

Query: 889  LRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGP 946
                G  G P  GL    P G+P       G  GPSGA+    G  G PG  G     GP
Sbjct: 964  PGQRGERGFP--GL--PGPSGEP-------GKQGPSGAS----GERGPPGPMGPPGLAGP 1008

Query: 947  LLQQGVGMRFEGPHGQSVAGLRFEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQG- 1003
              + G   R   P  +   G   +G     G  G     GP G PG      GP+   G 
Sbjct: 1009 PGESG---REGAPGAEGSPGR--DGSPGAKGDRGETGPAGPPGAPGAP-GAPGPVGPAGK 1062

Query: 1004 GGMRFE----GPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPR--FDGLHG 1057
             G R E    GP+ P G +   GP G  GPR +        G+ G   +     F GL G
Sbjct: 1063 SGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGET----GEQGDRGIKGHRGFSGLQG 1118

Query: 1058 QPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVP 1091
             PGP    +PG+ GP    GP G +  P   G P
Sbjct: 1119 PPGP--PGSPGEQGPSGASGPAGPRGPPGSAGAP 1150



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 130/420 (30%), Positives = 150/420 (35%), Gaps = 57/420 (13%)

Query: 777  SPRIDGPPTPASLR-FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFE 835
            SP  +G P     R   G  G+ G  GP    G  G  G   P    GP GP G P    
Sbjct: 291  SPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFP-GAV 349

Query: 836  GPIGQAGGGGFR-FEGSPGLRFE-GSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEG 893
            G  G+AG  G R  EG  G+R E G PG     GP G P       G  GQP      +G
Sbjct: 350  GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP-------GADGQPGA----KG 398

Query: 894  PHGQP--VGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFE-GPLLQQ 950
             +G P   G   F   RG P G     G  GP G +     P  +   G + E GP+  Q
Sbjct: 399  ANGAPGIAGAPGFPGARG-PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ 457

Query: 951  GVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQ-GGGMRFE 1009
            G      GP G+       EG+    G      GP G PG      GP  +   G     
Sbjct: 458  GP----PGPAGE-------EGKRGARGE----PGPTGLPGPPGERGGPGSRGFPGADGVA 502

Query: 1010 GPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPG-PRFERTPG 1068
            GP  P G     GP G  G   E        G+PG+   LP   GL G PG P  +   G
Sbjct: 503  GPKGPAGERGSPGPAGPKGSPGEA-------GRPGEAG-LPGAKGLTGSPGSPGPDGKTG 554

Query: 1069 QPGPQRFDGPPGQQVQP--RFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLES 1126
             PGP   DG PG    P  R       F GP+           G  G R    P   +  
Sbjct: 555  PPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEP-----GKAGERGVPGPPGAVGP 609

Query: 1127 VSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHG----PGNQSFSNPL 1182
               +       PPG A  A  +G Q       F    GP   GP G    PG Q     L
Sbjct: 610  AGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGP--AGPPGEAGKPGEQGVPGDL 667



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 133/444 (29%), Positives = 161/444 (36%), Gaps = 82/444 (18%)

Query: 771  EGPN-KLSPRIDGPPTPASLRF-DGSPGQMGGGGPLRFEGPQGQ--LGGGCP-------- 818
            EGP     PR  GP  PA     DG PGQ G  GP    GP G   LGG           
Sbjct: 111  EGPKGDTGPR--GPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYD 168

Query: 819  ------LRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFE-GSPGGLRFEGPGGQ 871
                  +   GP GP G P    GP G  G  G  F+G PG   E G+ G +   GP G 
Sbjct: 169  EKSTGGISVPGPMGPSG-PRGLPGPPGAPGPQG--FQGPPGEPGEPGASGPMGPRGPPGP 225

Query: 872  PVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQP-----VGGLRFEGGHGPSGA 926
            P G    +G  G+P G     GP G P G        G P      G    +G  G +G 
Sbjct: 226  P-GKNGDDGEAGKP-GRPGERGPPG-PQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGP 282

Query: 927  AIRFDGPHGQPG--GGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEG 984
            A    GP G+PG  G     G +  +G+      P     AG R         G     G
Sbjct: 283  A----GPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTG 338

Query: 985  PHGQPG----VGIRFE-GPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRF 1039
            P G PG    VG + E GP   +G     EGP    G     GP G  GP          
Sbjct: 339  PAGPPGFPGAVGAKGEAGPQGPRGS----EGPQGVRGEPGPPGPAGAAGPAGNP----GA 390

Query: 1040 DGQPGQPSLLPRFDGLHGQPG----PRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFD 1095
            DGQPG         G +G PG    P F    G  GPQ   GPPG +      G P    
Sbjct: 391  DGQPGA-------KGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAP---- 439

Query: 1096 GPQHQQASRFDI-PLGLQGTRFDNHPSQRLESVSFNQTGPYN--DPPGNAFNAPSQGLQF 1152
            G +    ++ +  P+G+QG        +  +  +  + GP     PPG      S+G   
Sbjct: 440  GSKGDTGAKGEPGPVGVQGP--PGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF-- 495

Query: 1153 QRHEQIFDSPQGPNFNGPHGPGNQ 1176
                     P      GP GP  +
Sbjct: 496  ---------PGADGVAGPKGPAGE 510



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 133/419 (31%), Positives = 154/419 (36%), Gaps = 79/419 (18%)

Query: 782  GPPT-PASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGT--PLRFEGPI 838
            GPP  P ++   G+ G+ G  GP   EGPQG  G        GPPGP G   P    G  
Sbjct: 341  GPPGFPGAV---GAKGEAGPQGPRGSEGPQGVRGE------PGPPGPAGAAGPAGNPGAD 391

Query: 839  GQAGGGGFRFEGSPGLR----FEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGP 894
            GQ G  G    G+PG+     F G+ G    +GPGG P G     G  G P G     G 
Sbjct: 392  GQPGAKG--ANGAPGIAGAPGFPGARGPSGPQGPGGPP-GPKGNSGEPGAP-GSKGDTGA 447

Query: 895  HGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGG-GIR-FEGPLLQQGV 952
             G+P G +    P G P G     G  G  G      GP G+ GG G R F G     GV
Sbjct: 448  KGEP-GPVGVQGPPG-PAGEEGKRGARGEPGPT-GLPGPPGERGGPGSRGFPG---ADGV 501

Query: 953  GMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPG-VGIRFEGPLVQQGGGMRFEGP 1011
                 GP G   AG R         G+    GP G PG  G   E  L    G     G 
Sbjct: 502  A----GPKGP--AGER---------GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGS 546

Query: 1012 SVPGGGLRIEGPLGQGG-PRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQP 1070
              P G     GP GQ G P   G    R  GQ G     P   G  G+PG   ER  G P
Sbjct: 547  PGPDGKTGPPGPAGQDGRPGPPGPPGAR--GQAGVMG-FPGPKGAAGEPGKAGER--GVP 601

Query: 1071 GPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFN 1130
            GP    GP G+  +    G P                P G  G R +  P+    S  F 
Sbjct: 602  GPPGAVGPAGKDGEAGAQGPPG---------------PAGPAGERGEQGPA---GSPGFQ 643

Query: 1131 QTGPYNDPPGNAFNAPSQGL---------QFQRHEQIFDSPQGPNFNGPHGPGNQSFSN 1180
                   PPG A     QG+            R E+ F   +G    GP GP     +N
Sbjct: 644  GLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERG--VQGPPGPAGPRGAN 700



 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 134/412 (32%), Positives = 153/412 (37%), Gaps = 56/412 (13%)

Query: 777  SPRIDGPPTPASLRFD-GSPGQMGGGGPLRFEGPQGQLGG-GCPLR--FEGPPGPVGTPL 832
            SP   G P PA    + G PG+ G  G L   GP G  G  G P     +GPPGP G P 
Sbjct: 639  SPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG-PR 697

Query: 833  RFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEG-PGGQPVGGLRF-EGHRGQ--PVGG 888
               G  G  G  G    G+PG    GS G    +G PG +   GL   +G RG   P G 
Sbjct: 698  GANGAPGNDGAKG--DAGAPGA--PGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753

Query: 889  LRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGG-GIRFE-GP 946
                G  G  V GL        P G    +G  GPSG A    GP G  G  G R E GP
Sbjct: 754  DGSPGKDG--VRGLTGPIGPPGPAGAPGDKGESGPSGPA----GPTGARGAPGDRGEPGP 807

Query: 947  LLQQGVGMRFEGPHG-QSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG-- 1003
                G    F GP G     G + E       G+    GP G  G      GP+   G  
Sbjct: 808  PGPAG----FAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGP----PGPIGNVGAP 859

Query: 1004 GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRF 1063
            G     G + P G     G  G+ GP     +A    G PG P       G  G  GPR 
Sbjct: 860  GAKGARGSAGPPGATGFPGAAGRVGPPGPSGNA----GPPGPPGPA----GKEGGKGPRG 911

Query: 1064 ERTP-GQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTR-FDNHPS 1121
            E  P G+PG     GPPG   +    G     DGP    A     P G+ G R     P 
Sbjct: 912  ETGPAGRPGEVGPPGPPGPAGEKGSPGA----DGP--AGAPGTPGPQGIAGQRGVVGLPG 965

Query: 1122 QRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQG-PNFNGPHG 1172
            QR E       GP  +P         QG      E+    P G P   GP G
Sbjct: 966  QRGERGFPGLPGPSGEP-------GKQGPSGASGERGPPGPMGPPGLAGPPG 1010



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 108/330 (32%), Positives = 125/330 (37%), Gaps = 63/330 (19%)

Query: 782  GPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGT--------PLR 833
            GPP P      G  G+ GG GP    GP G+ G   P    GPPGP G         P  
Sbjct: 893  GPPGPP-----GPAGKEGGKGPRGETGPAGRPGEVGP---PGPPGPAGEKGSPGADGPAG 944

Query: 834  FEGPIGQAGGGGFR-FEGSPGLRFE-GSPGGLRFEGPGGQP--VGGLRFEGHRGQP--VG 887
              G  G  G  G R   G PG R E G PG     GP G+P   G     G RG P  +G
Sbjct: 945  APGTPGPQGIAGQRGVVGLPGQRGERGFPG---LPGPSGEPGKQGPSGASGERGPPGPMG 1001

Query: 888  GLRFEGPHGQPVGGLRFDNPRGQPV--GGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEG 945
                 GP G+  G        G P   G    +G  G +G A    GP G PG      G
Sbjct: 1002 PPGLAGPPGES-GREGAPGAEGSPGRDGSPGAKGDRGETGPA----GPPGAPGAP-GAPG 1055

Query: 946  PLLQQGV-GMRFE-GPHGQSVAGLRFEGQHNQLG--GNLRFEGPHGQPG-VGIRFEGPLV 1000
            P+   G  G R E GP G +       G    +G  G    +GP G  G  G + +  + 
Sbjct: 1056 PVGPAGKSGDRGETGPAGPA-------GPVGPVGARGPAGPQGPRGDKGETGEQGDRGIK 1108

Query: 1001 QQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPG 1060
               G    +GP  P G    +GP G  GP           G PG     P  DGL+G PG
Sbjct: 1109 GHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR-------GPPGSAGA-PGKDGLNGLPG 1160

Query: 1061 PRFERTP----------GQPGPQRFDGPPG 1080
            P     P          G PGP    GPPG
Sbjct: 1161 PIGPPGPRGRTGDAGPVGPPGPPGPPGPPG 1190



 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 109/331 (32%), Positives = 127/331 (38%), Gaps = 69/331 (20%)

Query: 754  GPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLR-FDGSPGQMGGGGPLRFEGPQGQ 812
            GP  P+  +  P     +GP   +P   GP   A  R   G PGQ G  G     GP G+
Sbjct: 926  GPPGPAGEKGSPGA---DGPAG-APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGE 981

Query: 813  LGGGCPLRFEG---PPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPG 869
             G   P    G   PPGP+G P    GP G++G      EG+PG   EGSPG  R   PG
Sbjct: 982  PGKQGPSGASGERGPPGPMGPP-GLAGPPGESGR-----EGAPGA--EGSPG--RDGSPG 1031

Query: 870  GQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIR 929
             +        G RG+        GP G P G        G PVG     G  G +G A  
Sbjct: 1032 AK--------GDRGET-------GPAGPP-GAPGAPGAPG-PVGPAGKSGDRGETGPA-- 1072

Query: 930  FDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQP 989
              GP G P G +   GP   QG       P G    G   E     + G+  F G  G P
Sbjct: 1073 --GPAG-PVGPVGARGPAGPQG-------PRGDK--GETGEQGDRGIKGHRGFSGLQGPP 1120

Query: 990  GVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGG-PRFEGCHALRFDGQPGQPSL 1048
            G             G    +GPS   G     GP G  G P  +G + L   G  G P  
Sbjct: 1121 G-----------PPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGL--PGPIGPPG- 1166

Query: 1049 LPRFDGLHGQPGPRFERTPGQPGPQRFDGPP 1079
             PR  G  G  GP     PG PGP    GPP
Sbjct: 1167 -PR--GRTGDAGP--VGPPGPPGPPGPPGPP 1192



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 127/428 (29%), Positives = 159/428 (37%), Gaps = 59/428 (13%)

Query: 781  DGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQ 840
            DG  +P      G  G  G        GP+G  G   P   +G PG  G P    GP G 
Sbjct: 97   DGSESPTDQETTGVEGPKGD------TGPRGPRGPAGPPGRDGIPGQPGLP-GPPGPPGP 149

Query: 841  AGGGGFRFEGSPGLRF---EGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQ 897
             G  G     +P L +   E S GG+   GP G P G     G  G P G   F+GP G+
Sbjct: 150  PGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMG-PSGPRGLPGPPGAP-GPQGFQGPPGE 207

Query: 898  P--VGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGV- 952
            P   G      PRG P G     G  G +G   R  G  G PG  G     G     G+ 
Sbjct: 208  PGEPGASGPMGPRGPP-GPPGKNGDDGEAGKPGR-PGERGPPGPQGARGLPGTAGLPGMK 265

Query: 953  GMR-FEGPHG----QSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIR--FEGPLVQQG-- 1003
            G R F G  G       AG + E       G     GP G PG   R    GP   +G  
Sbjct: 266  GHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGND 325

Query: 1004 ---GGMRFEGPSVPG------GGLRIEGPLGQGGPR-FEGCHALRFDGQPGQPSLLPRFD 1053
               G     GP+ P       G +  +G  G  GPR  EG   +R  G+PG P       
Sbjct: 326  GATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR--GEPGPPGPAGA-A 382

Query: 1054 GLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQG 1113
            G  G PG       GQPG +  +G PG    P F G  +   GPQ         P G +G
Sbjct: 383  GPAGNPG-----ADGQPGAKGANGAPGIAGAPGFPGA-RGPSGPQGPGG-----PPGPKG 431

Query: 1114 TRFD-NHPSQRLESVSFNQTGP--YNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGP 1170
               +   P  + ++ +  + GP     PPG A     +G + +        P G      
Sbjct: 432  NSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGER---- 487

Query: 1171 HGPGNQSF 1178
             GPG++ F
Sbjct: 488  GGPGSRGF 495



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 35/102 (34%), Positives = 39/102 (38%), Gaps = 22/102 (21%)

Query: 780  IDGPPTPASLRFDGSPGQMG---GGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEG 836
            + GPP P      GSPG+ G     GP    GP G  G        G PGP+G P    G
Sbjct: 1116 LQGPPGPP-----GSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPP----G 1166

Query: 837  PIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRF 878
            P G+ G  G            G PG     GP G P  G  F
Sbjct: 1167 PRGRTGDAG----------PVGPPGPPGPPGPPGPPSAGFDF 1198


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 153/506 (30%), Positives = 191/506 (37%), Gaps = 116/506 (22%)

Query: 750  PLFDGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGP 809
            P+     R S    GP  +    P +  P+  GPP PA  +  G+PG+ G  GP   +G 
Sbjct: 1067 PVGSPGERGSAGTAGPIGL----PGRPGPQ--GPPGPAGEK--GAPGEKGPQGPAGRDGV 1118

Query: 810  QGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFE-GSPGGLRFEGP 868
            QG +G        GP GP G+P   +G  G+ G  G +  GS G + E G PG    +GP
Sbjct: 1119 QGPVG------LPGPAGPAGSPGE-DGDKGEIGEPGQK--GSKGDKGENGPPGPPGLQGP 1169

Query: 869  GGQP--VGGLRFEGHRGQ--------PVGGLRFEGPHGQPVGGLRFDNPRGQ-------- 910
             G P   GG    G RGQ          G   F GP G P+G      P G+        
Sbjct: 1170 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG-PIGLQGLPGPPGEKGENGDVG 1228

Query: 911  ---PVGGLRFEGGHGPSGAAIRFDGPHGQPG-----GGIRFEGPLLQQGVGMRFEGPHGQ 962
               P G     G  GP+GA    DGP G PG     GG+  +G   + G      GP G+
Sbjct: 1229 PMGPPGPPGPRGPQGPNGA----DGPQGPPGSVGSVGGVGEKGEPGEAG----NPGPPGE 1280

Query: 963  S-VAGLRFE-GQHNQLG-----------GNLRFEGPHGQPG-VGIRFE-------GPLVQ 1001
            + V G + E G+  + G           G    +GP G PG VG   +       GP  Q
Sbjct: 1281 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1340

Query: 1002 QG-GGMRFE-------GPSVPGGGLRIEGPLGQGGP----RFEGCHALR-------FDGQ 1042
             G GG + E       GP  P G     GP G+ GP      EG    +        +G 
Sbjct: 1341 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1400

Query: 1043 PGQ--------PSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGV---P 1091
            PG+        P+  P  +GL G PGP  E+  G PG    DGPPG    P   G+   P
Sbjct: 1401 PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ--GLPGAAGQDGPPGPMGPPGLPGLKGDP 1458

Query: 1092 QRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQ 1151
                   H        P G QG + D        S      G    P G        GL 
Sbjct: 1459 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL- 1517

Query: 1152 FQRHEQIFDSPQGPNFN-GPHGPGNQ 1176
                      PQGP  N G  GP  Q
Sbjct: 1518 --------PGPQGPKGNKGSTGPAGQ 1535



 Score = 97.8 bits (242), Expect = 7e-20
 Identities = 145/487 (29%), Positives = 186/487 (38%), Gaps = 131/487 (26%)

Query: 753  DGPSRPSV-ARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQG 811
            DG   P++ A++   + I +   +    + GPP P  L   G PG +GG G    +G  G
Sbjct: 514  DGSKGPTISAQEAQAQAILQ---QARIALRGPPGPMGLT--GRPGPVGGPGSSGAKGESG 568

Query: 812  QLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGG-GGFRFEGSPGLR----FEGSPG----- 861
              G   P   +GPPGP G P    G  G+ G  GG    G PG +    F+G PG     
Sbjct: 569  DPGPQGPRGVQGPPGPTGKP----GKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 624

Query: 862  GLRFE-GPGGQP----VGGLRFE----GHRGQP--VGGLRFEGPHGQP-----VGGLRFD 905
            G R E GP G P      G+R E    G RG P   G     GP G P      G    D
Sbjct: 625  GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 684

Query: 906  NPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQ-SV 964
             P G P G +  +G  GP G      GP G PG     +GP+   G     +GP G+  +
Sbjct: 685  GPPG-PKGNMGPQGEPGPPGQQGN-PGPQGLPGP----QGPIGPPGE----KGPQGKPGL 734

Query: 965  AGL----------RFEGQHNQLG--------GNLRFEGPHGQPGV-GIR----------- 994
            AGL            EGQ  + G        G + + GP G  G  G+R           
Sbjct: 735  AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 794

Query: 995  -----FEGPLVQQG-----GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCH--ALRFDGQ 1042
                 F+G +  +G     G +   G   P G     GP G  GP  +      L   G 
Sbjct: 795  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGL 854

Query: 1043 PGQPSL--------LPRFDGLHGQ---------PGPRFERTP-------------GQPGP 1072
            PG P           P F G +G+         PGPR +R P             G+PGP
Sbjct: 855  PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 914

Query: 1073 QRF---DGPPGQQVQ--PRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESV 1127
            +     DGPPG   +  P+    P  F GP+         P G  G     HP QR E+ 
Sbjct: 915  KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG-----PPGKDG--LPGHPGQRGETG 967

Query: 1128 SFNQTGP 1134
               +TGP
Sbjct: 968  FQGKTGP 974



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 140/452 (30%), Positives = 167/452 (36%), Gaps = 69/452 (15%)

Query: 783  PPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAG 842
            P  P     DG PG  G  GP    GP GQ G   P    GP GP+G P   +GP G+ G
Sbjct: 675  PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE-KGPQGKPG 733

Query: 843  GGGF-RFEGSPG-LRFEGSPGGLRFEGPGGQPVGGLRFEGHRG----QPVGGLR----FE 892
              G    +G PG    EG  G     GP G P G + + G RG      V GL+     +
Sbjct: 734  LAGLPGADGPPGHPGKEGQSGEKGALGPPG-PQGPIGYPGPRGVKGADGVRGLKGSKGEK 792

Query: 893  GPHGQP--VGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLL 948
            G  G P   G +     RG+ VG +   G  GP G   R  GP G PG  G    +G L 
Sbjct: 793  GEDGFPGFKGDMGLKGDRGE-VGQIGPRGEDGPEGPKGR-AGPTGDPGPSGQAGEKGKLG 850

Query: 949  QQGVG--MRFEGPHGQSVAGLRFEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQG- 1003
              G+      +GP G S     F G + + G  G     GP GQ G      GP   +G 
Sbjct: 851  VPGLPGYPGRQGPKG-STGFPGFPGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGA 905

Query: 1004 -GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPR 1062
             G     GP    GG    GP G+ GP+      + F G  G P   P  DGL G PG R
Sbjct: 906  RGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ-GPVGFPGPKGPPG-PPGKDGLPGHPGQR 963

Query: 1063 ----FERTPGQPGPQRF---------------------DGPPGQQVQPRFDGVPQRFDGP 1097
                F+   G PGP                         GPPG+Q  P   G       P
Sbjct: 964  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1023

Query: 1098 QHQQASRFDIPLGLQG-------TRFDNHPSQRLESVSFNQTGPYNDP--PGNAFNAPSQ 1148
              Q  S  D P GL+G             P  +         GP   P   G+A  A   
Sbjct: 1024 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1083

Query: 1149 GLQFQRHEQIFDSPQG----PNFNGPHGPGNQ 1176
            GL  +   Q    P G    P   GP GP  +
Sbjct: 1084 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1115



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 116/380 (30%), Positives = 145/380 (38%), Gaps = 102/380 (26%)

Query: 782  GPPTPASLR-FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQ 840
            GPP P  L+   G PG+ G  G +   GP G  G   P    G  GP G P    G +G 
Sbjct: 1204 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP----GSVGS 1259

Query: 841  AGGGGFRFE-------GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEG 893
             GG G + E       G PG    G P G R E     P G     G +G P      +G
Sbjct: 1260 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD----DG 1315

Query: 894  PHGQP--VGGLRFDNPRGQP-------VGGLRFEGGH-------GPSGAAIRFDGPHGQP 937
            P G P  VG      P G+P       VGG + E G        GPSG A    GP G P
Sbjct: 1316 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA----GPPGPP 1371

Query: 938  G-----GGIRFEGPLLQQGVGMRF--EGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPG 990
            G     G    EG   ++G       EGP G++              G +  +GP G+PG
Sbjct: 1372 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT--------------GPVGPQGPAGKPG 1417

Query: 991  V-GIR-FEGPLVQQG--GGMRFEGPSVPGG-----GLR----------------IEGPLG 1025
              G+R   GP+ +QG  G    +GP  P G     GL+                + GP G
Sbjct: 1418 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1477

Query: 1026 QGG-------PRFEGCHALRFDGQ---PGQPSLLPRFDGLHGQPGPRFER---------- 1065
            + G       P  +G    + DG    P  P   P   GL G  GP+  +          
Sbjct: 1478 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1537

Query: 1066 TPGQPGPQRFDGPPGQQVQP 1085
              G PGP    GPPG+ +QP
Sbjct: 1538 DSGLPGPPGSPGPPGEVIQP 1557



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 106/333 (31%), Positives = 127/333 (38%), Gaps = 81/333 (24%)

Query: 780  IDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIG 839
            ++GPP PA              GP    GP G          +GP GP G P    GP G
Sbjct: 452  VEGPPGPA--------------GPAGIMGPPG---------LQGPTGPPGDP-GDRGPPG 487

Query: 840  QAGGGGFRFEGSPGLRFEGSPGGL-----RFEGPG--GQPVGGLRFEGHRGQPVGGLRFE 892
            + G       G+ GL   G PG +     R+ G G  G  +     +         +   
Sbjct: 488  RPG-----LPGADGL--PGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALR 540

Query: 893  GPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGV 952
            GP G P+G       R  PVGG    G  G SG      GP G P G     GP  + G 
Sbjct: 541  GPPG-PMG----LTGRPGPVGGPGSSGAKGESGD----PGPQG-PRGVQGPPGPTGKPGK 590

Query: 953  GMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPG-VGIRFE-GPLVQQG----GGM 1006
              R     G+ + G           G+  F+G  G PG  G R E GP    G     GM
Sbjct: 591  RGRPGADGGRGMPG------EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 644

Query: 1007 RFEGPSVPGGGLRIE-GPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFER 1065
            R E   +   GL  E GP G  GPR          G PGQP +     G+ G PGP+   
Sbjct: 645  RGEDGEIGPRGLPGEAGPRGLLGPR-------GTPGAPGQPGMA----GVDGPPGPK--- 690

Query: 1066 TPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQ 1098
              G  GPQ   GPPGQQ  P   G+P    GPQ
Sbjct: 691  --GNMGPQGEPGPPGQQGNPGPQGLP----GPQ 717



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 115/394 (29%), Positives = 140/394 (35%), Gaps = 57/394 (14%)

Query: 809  PQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGP 868
            P  + G G P   +       T +   G  G+ G  G      PG+  EG PG     GP
Sbjct: 409  PNEEFGPGVPAETD----ITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGP---AGP 461

Query: 869  GGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFE---GGHGPSG 925
             G  +G    +G  G P G     GP G+P G    D   G P   L      GG G  G
Sbjct: 462  AG-IMGPPGLQGPTGPP-GDPGDRGPPGRP-GLPGADGLPGPPGTMLMLPFRYGGDGSKG 518

Query: 926  AAIRFDGPHGQ---PGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRF 982
              I       Q       I   GP    G+  R     G   +G + E       G    
Sbjct: 519  PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 578

Query: 983  EGPHGQPGVGIRFEGPLVQQGGGM----------RFEG-PSVPG--GGLRIEGPLGQGGP 1029
            +GP G  G   +   P    G GM           F+G P +PG  G     GP G  GP
Sbjct: 579  QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 638

Query: 1030 RFEGCHALR-FDGQPGQPSLLPRFDGLHGQPGPR-FERTPGQPGPQRFDGPPGQQVQPRF 1087
               G   +R  DG+ G P  LP   G  G  GPR     PGQPG    DGPPG    P+ 
Sbjct: 639  --PGDDGMRGEDGEIG-PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG----PKG 691

Query: 1088 DGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDP-----PGNA 1142
            +  PQ   GP  QQ +    P GL G +    P          + GP   P     PG  
Sbjct: 692  NMGPQGEPGPPGQQGN--PGPQGLPGPQGPIGPP--------GEKGPQGKPGLAGLPGAD 741

Query: 1143 FNAPSQGLQFQRHEQIFDSPQGP----NFNGPHG 1172
                  G + Q  E+    P GP     + GP G
Sbjct: 742  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRG 775


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 153/506 (30%), Positives = 191/506 (37%), Gaps = 116/506 (22%)

Query: 750  PLFDGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGP 809
            P+     R S    GP  +    P +  P+  GPP PA  +  G+PG+ G  GP   +G 
Sbjct: 1016 PVGSPGERGSAGTAGPIGL----PGRPGPQ--GPPGPAGEK--GAPGEKGPQGPAGRDGV 1067

Query: 810  QGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFE-GSPGGLRFEGP 868
            QG +G        GP GP G+P   +G  G+ G  G +  GS G + E G PG    +GP
Sbjct: 1068 QGPVG------LPGPAGPAGSPGE-DGDKGEIGEPGQK--GSKGDKGENGPPGPPGLQGP 1118

Query: 869  GGQP--VGGLRFEGHRGQ--------PVGGLRFEGPHGQPVGGLRFDNPRGQ-------- 910
             G P   GG    G RGQ          G   F GP G P+G      P G+        
Sbjct: 1119 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG-PIGLQGLPGPPGEKGENGDVG 1177

Query: 911  ---PVGGLRFEGGHGPSGAAIRFDGPHGQPG-----GGIRFEGPLLQQGVGMRFEGPHGQ 962
               P G     G  GP+GA    DGP G PG     GG+  +G   + G      GP G+
Sbjct: 1178 PMGPPGPPGPRGPQGPNGA----DGPQGPPGSVGSVGGVGEKGEPGEAG----NPGPPGE 1229

Query: 963  S-VAGLRFE-GQHNQLG-----------GNLRFEGPHGQPG-VGIRFE-------GPLVQ 1001
            + V G + E G+  + G           G    +GP G PG VG   +       GP  Q
Sbjct: 1230 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1289

Query: 1002 QG-GGMRFE-------GPSVPGGGLRIEGPLGQGGP----RFEGCHALR-------FDGQ 1042
             G GG + E       GP  P G     GP G+ GP      EG    +        +G 
Sbjct: 1290 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1349

Query: 1043 PGQ--------PSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGV---P 1091
            PG+        P+  P  +GL G PGP  E+  G PG    DGPPG    P   G+   P
Sbjct: 1350 PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ--GLPGAAGQDGPPGPMGPPGLPGLKGDP 1407

Query: 1092 QRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQ 1151
                   H        P G QG + D        S      G    P G        GL 
Sbjct: 1408 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL- 1466

Query: 1152 FQRHEQIFDSPQGPNFN-GPHGPGNQ 1176
                      PQGP  N G  GP  Q
Sbjct: 1467 --------PGPQGPKGNKGSTGPAGQ 1484



 Score = 97.8 bits (242), Expect = 7e-20
 Identities = 145/487 (29%), Positives = 186/487 (38%), Gaps = 131/487 (26%)

Query: 753  DGPSRPSV-ARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQG 811
            DG   P++ A++   + I +   +    + GPP P  L   G PG +GG G    +G  G
Sbjct: 463  DGSKGPTISAQEAQAQAILQ---QARIALRGPPGPMGLT--GRPGPVGGPGSSGAKGESG 517

Query: 812  QLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGG-GGFRFEGSPGLR----FEGSPG----- 861
              G   P   +GPPGP G P    G  G+ G  GG    G PG +    F+G PG     
Sbjct: 518  DPGPQGPRGVQGPPGPTGKP----GKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 573

Query: 862  GLRFE-GPGGQP----VGGLRFE----GHRGQP--VGGLRFEGPHGQP-----VGGLRFD 905
            G R E GP G P      G+R E    G RG P   G     GP G P      G    D
Sbjct: 574  GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 633

Query: 906  NPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQ-SV 964
             P G P G +  +G  GP G      GP G PG     +GP+   G     +GP G+  +
Sbjct: 634  GPPG-PKGNMGPQGEPGPPGQQGN-PGPQGLPGP----QGPIGPPGE----KGPQGKPGL 683

Query: 965  AGL----------RFEGQHNQLG--------GNLRFEGPHGQPGV-GIR----------- 994
            AGL            EGQ  + G        G + + GP G  G  G+R           
Sbjct: 684  AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 743

Query: 995  -----FEGPLVQQG-----GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCH--ALRFDGQ 1042
                 F+G +  +G     G +   G   P G     GP G  GP  +      L   G 
Sbjct: 744  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGL 803

Query: 1043 PGQPSL--------LPRFDGLHGQ---------PGPRFERTP-------------GQPGP 1072
            PG P           P F G +G+         PGPR +R P             G+PGP
Sbjct: 804  PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 863

Query: 1073 QRF---DGPPGQQVQ--PRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESV 1127
            +     DGPPG   +  P+    P  F GP+         P G  G     HP QR E+ 
Sbjct: 864  KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG-----PPGKDG--LPGHPGQRGETG 916

Query: 1128 SFNQTGP 1134
               +TGP
Sbjct: 917  FQGKTGP 923



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 140/452 (30%), Positives = 167/452 (36%), Gaps = 69/452 (15%)

Query: 783  PPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAG 842
            P  P     DG PG  G  GP    GP GQ G   P    GP GP+G P   +GP G+ G
Sbjct: 624  PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE-KGPQGKPG 682

Query: 843  GGGF-RFEGSPG-LRFEGSPGGLRFEGPGGQPVGGLRFEGHRG----QPVGGLR----FE 892
              G    +G PG    EG  G     GP G P G + + G RG      V GL+     +
Sbjct: 683  LAGLPGADGPPGHPGKEGQSGEKGALGPPG-PQGPIGYPGPRGVKGADGVRGLKGSKGEK 741

Query: 893  GPHGQP--VGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLL 948
            G  G P   G +     RG+ VG +   G  GP G   R  GP G PG  G    +G L 
Sbjct: 742  GEDGFPGFKGDMGLKGDRGE-VGQIGPRGEDGPEGPKGR-AGPTGDPGPSGQAGEKGKLG 799

Query: 949  QQGVG--MRFEGPHGQSVAGLRFEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQG- 1003
              G+      +GP G S     F G + + G  G     GP GQ G      GP   +G 
Sbjct: 800  VPGLPGYPGRQGPKG-STGFPGFPGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGA 854

Query: 1004 -GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPR 1062
             G     GP    GG    GP G+ GP+      + F G  G P   P  DGL G PG R
Sbjct: 855  RGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ-GPVGFPGPKGPPG-PPGKDGLPGHPGQR 912

Query: 1063 ----FERTPGQPGPQRF---------------------DGPPGQQVQPRFDGVPQRFDGP 1097
                F+   G PGP                         GPPG+Q  P   G       P
Sbjct: 913  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 972

Query: 1098 QHQQASRFDIPLGLQG-------TRFDNHPSQRLESVSFNQTGPYNDP--PGNAFNAPSQ 1148
              Q  S  D P GL+G             P  +         GP   P   G+A  A   
Sbjct: 973  GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1032

Query: 1149 GLQFQRHEQIFDSPQG----PNFNGPHGPGNQ 1176
            GL  +   Q    P G    P   GP GP  +
Sbjct: 1033 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1064



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 116/380 (30%), Positives = 145/380 (38%), Gaps = 102/380 (26%)

Query: 782  GPPTPASLR-FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQ 840
            GPP P  L+   G PG+ G  G +   GP G  G   P    G  GP G P    G +G 
Sbjct: 1153 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP----GSVGS 1208

Query: 841  AGGGGFRFE-------GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEG 893
             GG G + E       G PG    G P G R E     P G     G +G P      +G
Sbjct: 1209 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD----DG 1264

Query: 894  PHGQP--VGGLRFDNPRGQP-------VGGLRFEGGH-------GPSGAAIRFDGPHGQP 937
            P G P  VG      P G+P       VGG + E G        GPSG A    GP G P
Sbjct: 1265 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA----GPPGPP 1320

Query: 938  G-----GGIRFEGPLLQQGVGMRF--EGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPG 990
            G     G    EG   ++G       EGP G++              G +  +GP G+PG
Sbjct: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT--------------GPVGPQGPAGKPG 1366

Query: 991  V-GIR-FEGPLVQQG--GGMRFEGPSVPGG-----GLR----------------IEGPLG 1025
              G+R   GP+ +QG  G    +GP  P G     GL+                + GP G
Sbjct: 1367 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1426

Query: 1026 QGG-------PRFEGCHALRFDGQ---PGQPSLLPRFDGLHGQPGPRFER---------- 1065
            + G       P  +G    + DG    P  P   P   GL G  GP+  +          
Sbjct: 1427 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1486

Query: 1066 TPGQPGPQRFDGPPGQQVQP 1085
              G PGP    GPPG+ +QP
Sbjct: 1487 DSGLPGPPGSPGPPGEVIQP 1506



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 106/333 (31%), Positives = 127/333 (38%), Gaps = 81/333 (24%)

Query: 780  IDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIG 839
            ++GPP PA              GP    GP G          +GP GP G P    GP G
Sbjct: 401  VEGPPGPA--------------GPAGIMGPPG---------LQGPTGPPGDP-GDRGPPG 436

Query: 840  QAGGGGFRFEGSPGLRFEGSPGGL-----RFEGPG--GQPVGGLRFEGHRGQPVGGLRFE 892
            + G       G+ GL   G PG +     R+ G G  G  +     +         +   
Sbjct: 437  RPG-----LPGADGL--PGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALR 489

Query: 893  GPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGV 952
            GP G P+G       R  PVGG    G  G SG      GP G P G     GP  + G 
Sbjct: 490  GPPG-PMG----LTGRPGPVGGPGSSGAKGESGD----PGPQG-PRGVQGPPGPTGKPGK 539

Query: 953  GMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPG-VGIRFE-GPLVQQG----GGM 1006
              R     G+ + G           G+  F+G  G PG  G R E GP    G     GM
Sbjct: 540  RGRPGADGGRGMPG------EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 593

Query: 1007 RFEGPSVPGGGLRIE-GPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFER 1065
            R E   +   GL  E GP G  GPR          G PGQP +     G+ G PGP+   
Sbjct: 594  RGEDGEIGPRGLPGEAGPRGLLGPR-------GTPGAPGQPGMA----GVDGPPGPK--- 639

Query: 1066 TPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQ 1098
              G  GPQ   GPPGQQ  P   G+P    GPQ
Sbjct: 640  --GNMGPQGEPGPPGQQGNPGPQGLP----GPQ 666



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 115/394 (29%), Positives = 140/394 (35%), Gaps = 57/394 (14%)

Query: 809  PQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGP 868
            P  + G G P   +       T +   G  G+ G  G      PG+  EG PG     GP
Sbjct: 358  PNEEFGPGVPAETD----ITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGP---AGP 410

Query: 869  GGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFE---GGHGPSG 925
             G  +G    +G  G P G     GP G+P G    D   G P   L      GG G  G
Sbjct: 411  AG-IMGPPGLQGPTGPP-GDPGDRGPPGRP-GLPGADGLPGPPGTMLMLPFRYGGDGSKG 467

Query: 926  AAIRFDGPHGQ---PGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRF 982
              I       Q       I   GP    G+  R     G   +G + E       G    
Sbjct: 468  PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 527

Query: 983  EGPHGQPGVGIRFEGPLVQQGGGM----------RFEG-PSVPG--GGLRIEGPLGQGGP 1029
            +GP G  G   +   P    G GM           F+G P +PG  G     GP G  GP
Sbjct: 528  QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 587

Query: 1030 RFEGCHALR-FDGQPGQPSLLPRFDGLHGQPGPR-FERTPGQPGPQRFDGPPGQQVQPRF 1087
               G   +R  DG+ G P  LP   G  G  GPR     PGQPG    DGPPG    P+ 
Sbjct: 588  --PGDDGMRGEDGEIG-PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG----PKG 640

Query: 1088 DGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDP-----PGNA 1142
            +  PQ   GP  QQ +    P GL G +    P          + GP   P     PG  
Sbjct: 641  NMGPQGEPGPPGQQGN--PGPQGLPGPQGPIGPP--------GEKGPQGKPGLAGLPGAD 690

Query: 1143 FNAPSQGLQFQRHEQIFDSPQGP----NFNGPHG 1172
                  G + Q  E+    P GP     + GP G
Sbjct: 691  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRG 724


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 153/506 (30%), Positives = 191/506 (37%), Gaps = 116/506 (22%)

Query: 750  PLFDGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGP 809
            P+     R S    GP  +    P +  P+  GPP PA  +  G+PG+ G  GP   +G 
Sbjct: 1055 PVGSPGERGSAGTAGPIGL----PGRPGPQ--GPPGPAGEK--GAPGEKGPQGPAGRDGV 1106

Query: 810  QGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFE-GSPGGLRFEGP 868
            QG +G        GP GP G+P   +G  G+ G  G +  GS G + E G PG    +GP
Sbjct: 1107 QGPVG------LPGPAGPAGSPGE-DGDKGEIGEPGQK--GSKGDKGENGPPGPPGLQGP 1157

Query: 869  GGQP--VGGLRFEGHRGQ--------PVGGLRFEGPHGQPVGGLRFDNPRGQ-------- 910
             G P   GG    G RGQ          G   F GP G P+G      P G+        
Sbjct: 1158 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG-PIGLQGLPGPPGEKGENGDVG 1216

Query: 911  ---PVGGLRFEGGHGPSGAAIRFDGPHGQPG-----GGIRFEGPLLQQGVGMRFEGPHGQ 962
               P G     G  GP+GA    DGP G PG     GG+  +G   + G      GP G+
Sbjct: 1217 PMGPPGPPGPRGPQGPNGA----DGPQGPPGSVGSVGGVGEKGEPGEAG----NPGPPGE 1268

Query: 963  S-VAGLRFE-GQHNQLG-----------GNLRFEGPHGQPG-VGIRFE-------GPLVQ 1001
            + V G + E G+  + G           G    +GP G PG VG   +       GP  Q
Sbjct: 1269 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1328

Query: 1002 QG-GGMRFE-------GPSVPGGGLRIEGPLGQGGP----RFEGCHALR-------FDGQ 1042
             G GG + E       GP  P G     GP G+ GP      EG    +        +G 
Sbjct: 1329 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1388

Query: 1043 PGQ--------PSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGV---P 1091
            PG+        P+  P  +GL G PGP  E+  G PG    DGPPG    P   G+   P
Sbjct: 1389 PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ--GLPGAAGQDGPPGPMGPPGLPGLKGDP 1446

Query: 1092 QRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQ 1151
                   H        P G QG + D        S      G    P G        GL 
Sbjct: 1447 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL- 1505

Query: 1152 FQRHEQIFDSPQGPNFN-GPHGPGNQ 1176
                      PQGP  N G  GP  Q
Sbjct: 1506 --------PGPQGPKGNKGSTGPAGQ 1523



 Score = 97.8 bits (242), Expect = 7e-20
 Identities = 145/487 (29%), Positives = 186/487 (38%), Gaps = 131/487 (26%)

Query: 753  DGPSRPSV-ARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQG 811
            DG   P++ A++   + I +   +    + GPP P  L   G PG +GG G    +G  G
Sbjct: 502  DGSKGPTISAQEAQAQAILQ---QARIALRGPPGPMGLT--GRPGPVGGPGSSGAKGESG 556

Query: 812  QLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGG-GGFRFEGSPGLR----FEGSPG----- 861
              G   P   +GPPGP G P    G  G+ G  GG    G PG +    F+G PG     
Sbjct: 557  DPGPQGPRGVQGPPGPTGKP----GKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 612

Query: 862  GLRFE-GPGGQP----VGGLRFE----GHRGQP--VGGLRFEGPHGQP-----VGGLRFD 905
            G R E GP G P      G+R E    G RG P   G     GP G P      G    D
Sbjct: 613  GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 672

Query: 906  NPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQ-SV 964
             P G P G +  +G  GP G      GP G PG     +GP+   G     +GP G+  +
Sbjct: 673  GPPG-PKGNMGPQGEPGPPGQQGN-PGPQGLPGP----QGPIGPPGE----KGPQGKPGL 722

Query: 965  AGL----------RFEGQHNQLG--------GNLRFEGPHGQPGV-GIR----------- 994
            AGL            EGQ  + G        G + + GP G  G  G+R           
Sbjct: 723  AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 782

Query: 995  -----FEGPLVQQG-----GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCH--ALRFDGQ 1042
                 F+G +  +G     G +   G   P G     GP G  GP  +      L   G 
Sbjct: 783  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGL 842

Query: 1043 PGQPSL--------LPRFDGLHGQ---------PGPRFERTP-------------GQPGP 1072
            PG P           P F G +G+         PGPR +R P             G+PGP
Sbjct: 843  PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 902

Query: 1073 QRF---DGPPGQQVQ--PRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESV 1127
            +     DGPPG   +  P+    P  F GP+         P G  G     HP QR E+ 
Sbjct: 903  KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG-----PPGKDG--LPGHPGQRGETG 955

Query: 1128 SFNQTGP 1134
               +TGP
Sbjct: 956  FQGKTGP 962



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 140/452 (30%), Positives = 167/452 (36%), Gaps = 69/452 (15%)

Query: 783  PPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAG 842
            P  P     DG PG  G  GP    GP GQ G   P    GP GP+G P   +GP G+ G
Sbjct: 663  PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE-KGPQGKPG 721

Query: 843  GGGF-RFEGSPG-LRFEGSPGGLRFEGPGGQPVGGLRFEGHRG----QPVGGLR----FE 892
              G    +G PG    EG  G     GP G P G + + G RG      V GL+     +
Sbjct: 722  LAGLPGADGPPGHPGKEGQSGEKGALGPPG-PQGPIGYPGPRGVKGADGVRGLKGSKGEK 780

Query: 893  GPHGQP--VGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLL 948
            G  G P   G +     RG+ VG +   G  GP G   R  GP G PG  G    +G L 
Sbjct: 781  GEDGFPGFKGDMGLKGDRGE-VGQIGPRGEDGPEGPKGR-AGPTGDPGPSGQAGEKGKLG 838

Query: 949  QQGVG--MRFEGPHGQSVAGLRFEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQG- 1003
              G+      +GP G S     F G + + G  G     GP GQ G      GP   +G 
Sbjct: 839  VPGLPGYPGRQGPKG-STGFPGFPGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGA 893

Query: 1004 -GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPR 1062
             G     GP    GG    GP G+ GP+      + F G  G P   P  DGL G PG R
Sbjct: 894  RGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ-GPVGFPGPKGPPG-PPGKDGLPGHPGQR 951

Query: 1063 ----FERTPGQPGPQRF---------------------DGPPGQQVQPRFDGVPQRFDGP 1097
                F+   G PGP                         GPPG+Q  P   G       P
Sbjct: 952  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1011

Query: 1098 QHQQASRFDIPLGLQG-------TRFDNHPSQRLESVSFNQTGPYNDP--PGNAFNAPSQ 1148
              Q  S  D P GL+G             P  +         GP   P   G+A  A   
Sbjct: 1012 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1071

Query: 1149 GLQFQRHEQIFDSPQG----PNFNGPHGPGNQ 1176
            GL  +   Q    P G    P   GP GP  +
Sbjct: 1072 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1103



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 116/380 (30%), Positives = 145/380 (38%), Gaps = 102/380 (26%)

Query: 782  GPPTPASLR-FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQ 840
            GPP P  L+   G PG+ G  G +   GP G  G   P    G  GP G P    G +G 
Sbjct: 1192 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP----GSVGS 1247

Query: 841  AGGGGFRFE-------GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEG 893
             GG G + E       G PG    G P G R E     P G     G +G P      +G
Sbjct: 1248 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD----DG 1303

Query: 894  PHGQP--VGGLRFDNPRGQP-------VGGLRFEGGH-------GPSGAAIRFDGPHGQP 937
            P G P  VG      P G+P       VGG + E G        GPSG A    GP G P
Sbjct: 1304 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA----GPPGPP 1359

Query: 938  G-----GGIRFEGPLLQQGVGMRF--EGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPG 990
            G     G    EG   ++G       EGP G++              G +  +GP G+PG
Sbjct: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT--------------GPVGPQGPAGKPG 1405

Query: 991  V-GIR-FEGPLVQQG--GGMRFEGPSVPGG-----GLR----------------IEGPLG 1025
              G+R   GP+ +QG  G    +GP  P G     GL+                + GP G
Sbjct: 1406 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1465

Query: 1026 QGG-------PRFEGCHALRFDGQ---PGQPSLLPRFDGLHGQPGPRFER---------- 1065
            + G       P  +G    + DG    P  P   P   GL G  GP+  +          
Sbjct: 1466 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1525

Query: 1066 TPGQPGPQRFDGPPGQQVQP 1085
              G PGP    GPPG+ +QP
Sbjct: 1526 DSGLPGPPGSPGPPGEVIQP 1545



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 106/333 (31%), Positives = 127/333 (38%), Gaps = 81/333 (24%)

Query: 780  IDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIG 839
            ++GPP PA              GP    GP G          +GP GP G P    GP G
Sbjct: 440  VEGPPGPA--------------GPAGIMGPPG---------LQGPTGPPGDP-GDRGPPG 475

Query: 840  QAGGGGFRFEGSPGLRFEGSPGGL-----RFEGPG--GQPVGGLRFEGHRGQPVGGLRFE 892
            + G       G+ GL   G PG +     R+ G G  G  +     +         +   
Sbjct: 476  RPG-----LPGADGL--PGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALR 528

Query: 893  GPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGV 952
            GP G P+G       R  PVGG    G  G SG      GP G P G     GP  + G 
Sbjct: 529  GPPG-PMG----LTGRPGPVGGPGSSGAKGESGD----PGPQG-PRGVQGPPGPTGKPGK 578

Query: 953  GMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPG-VGIRFE-GPLVQQG----GGM 1006
              R     G+ + G           G+  F+G  G PG  G R E GP    G     GM
Sbjct: 579  RGRPGADGGRGMPG------EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 632

Query: 1007 RFEGPSVPGGGLRIE-GPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFER 1065
            R E   +   GL  E GP G  GPR          G PGQP +     G+ G PGP+   
Sbjct: 633  RGEDGEIGPRGLPGEAGPRGLLGPR-------GTPGAPGQPGMA----GVDGPPGPK--- 678

Query: 1066 TPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQ 1098
              G  GPQ   GPPGQQ  P   G+P    GPQ
Sbjct: 679  --GNMGPQGEPGPPGQQGNPGPQGLP----GPQ 705



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 115/394 (29%), Positives = 140/394 (35%), Gaps = 57/394 (14%)

Query: 809  PQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGP 868
            P  + G G P   +       T +   G  G+ G  G      PG+  EG PG     GP
Sbjct: 397  PNEEFGPGVPAETD----ITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGP---AGP 449

Query: 869  GGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFE---GGHGPSG 925
             G  +G    +G  G P G     GP G+P G    D   G P   L      GG G  G
Sbjct: 450  AG-IMGPPGLQGPTGPP-GDPGDRGPPGRP-GLPGADGLPGPPGTMLMLPFRYGGDGSKG 506

Query: 926  AAIRFDGPHGQ---PGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRF 982
              I       Q       I   GP    G+  R     G   +G + E       G    
Sbjct: 507  PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 566

Query: 983  EGPHGQPGVGIRFEGPLVQQGGGM----------RFEG-PSVPG--GGLRIEGPLGQGGP 1029
            +GP G  G   +   P    G GM           F+G P +PG  G     GP G  GP
Sbjct: 567  QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 626

Query: 1030 RFEGCHALR-FDGQPGQPSLLPRFDGLHGQPGPR-FERTPGQPGPQRFDGPPGQQVQPRF 1087
               G   +R  DG+ G P  LP   G  G  GPR     PGQPG    DGPPG    P+ 
Sbjct: 627  --PGDDGMRGEDGEIG-PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG----PKG 679

Query: 1088 DGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDP-----PGNA 1142
            +  PQ   GP  QQ +    P GL G +    P          + GP   P     PG  
Sbjct: 680  NMGPQGEPGPPGQQGN--PGPQGLPGPQGPIGPP--------GEKGPQGKPGLAGLPGAD 729

Query: 1143 FNAPSQGLQFQRHEQIFDSPQGP----NFNGPHG 1172
                  G + Q  E+    P GP     + GP G
Sbjct: 730  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRG 763


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 98.2 bits (243), Expect = 5e-20
 Identities = 113/353 (32%), Positives = 145/353 (41%), Gaps = 85/353 (24%)

Query: 783  PPTPASLRFD-----------GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGT- 830
            PPTP S +             G  G+MG  GP+   GP+G +G   P+   GP G  G  
Sbjct: 460  PPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDV 519

Query: 831  --------------PLRFEGPIGQAGGGGFRFEGSPG-LRFEGSPGGLRFEGPGGQP--- 872
                           L   GP G+ G  G R  G PG L   G PG +   GP G P   
Sbjct: 520  GIGPFGQGEKGEKGSLGLPGPPGRDGSKGMR--GEPGELGEPGLPGEVGMRGPQGPPGLP 577

Query: 873  -----VGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAA 927
                 VG    +G RG+       +G  G+  G    D   G+P G    +G  GPSG A
Sbjct: 578  GPPGRVGAPGLQGERGE-------KGTRGEK-GERGLDGFPGKP-GDTGQQGRPGPSGVA 628

Query: 928  --------IRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVA----GLRFEGQHNQ 975
                    +   GP G PG  ++ EG   +QG      GP G   A    G R       
Sbjct: 629  GPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGA----PGPRGHQGAPGPPGAR------- 677

Query: 976  LGGNLRFEGPHGQPGV-GIR-FEGPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGG-PR 1030
              G +  EG  G PG+ G+R  +G +   G  G +  +GP  P G   + GP G GG P 
Sbjct: 678  --GPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPG---VPGPPGPGGSPG 732

Query: 1031 FEGCHALRFDGQPGQPSLL--PRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQ 1081
              G   + F G+PG P     P  DG +G PGP    T G+PG +  DG PG+
Sbjct: 733  LPG--EIGFPGKPGPPGPTGPPGKDGPNGPPGP--PGTKGEPGERGEDGLPGK 781



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 114/340 (33%), Positives = 139/340 (40%), Gaps = 65/340 (19%)

Query: 792  DGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE-G 850
            +G PG+ G  GP   +GPQG  G   P    G PG  G P    GP G  G  G + E G
Sbjct: 1302 EGLPGKDGDTGPTGPQGPQGPRG---PPGKNGSPGSPGEP----GPSGTPGQKGSKGENG 1354

Query: 851  SPGLRFEGSPGGLRFEGPGGQP--VGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNP- 907
            SPGL     PG L   GP G+P   G    EG  G+P G   F+G  G P  G++ D   
Sbjct: 1355 SPGL-----PGFLGPRGPPGEPGEKGVPGKEGVPGKP-GEPGFKGERGDP--GIKGDKGP 1406

Query: 908  ---RGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGV-GMRFEGPHG 961
               +GQP G     G  G +G      GP G PG  G +   GP  Q G  G+R E P  
Sbjct: 1407 PGGKGQP-GDPGIPGHKGHTGLM----GPQGLPGENGPVGPPGPPGQPGFPGLRGESPSM 1461

Query: 962  QSVAGLRFEGQHNQLGGNLRF----------------EGPHGQPGVGIRFEGPLVQQGGG 1005
            +++  L  E    QL   L +                 GP G PG     +  L  + G 
Sbjct: 1462 ETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPG-----KDGLPGRAGP 1516

Query: 1006 MRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSL-------LPRFDGLHGQ 1058
            M   G    GG   +EGP G  GP+ E        G PG P +        P   G  G+
Sbjct: 1517 MGEPGRPGQGG---LEGPSGPIGPKGER----GAKGDPGAPGVGLRGEMGPPGIPGQPGE 1569

Query: 1059 PGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQ 1098
            PG   +  PG PGPQ   GP G    P   G P + D  Q
Sbjct: 1570 PGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQ 1609



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 113/336 (33%), Positives = 138/336 (41%), Gaps = 63/336 (18%)

Query: 793  GSPGQMGGGGPLRF---EGPQGQLGGGCPLRFEGPPGPVGTPLR--------FEGPIGQA 841
            G+PG  G  G +     EG  G+ G   P   +GP GP G P +          GP G  
Sbjct: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTP 1344

Query: 842  GGGGFRFE-GSPGLRFEGSPGGLRFEGPGGQP--VGGLRFEGHRGQPVGGLRFEGPHGQP 898
            G  G + E GSPGL     PG L   GP G+P   G    EG  G+P G   F+G  G P
Sbjct: 1345 GQKGSKGENGSPGL-----PGFLGPRGPPGEPGEKGVPGKEGVPGKP-GEPGFKGERGDP 1398

Query: 899  VGGLRFD----NPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGV 952
              G++ D      +GQP G     G  G +G      GP G PG  G +   GP  Q G 
Sbjct: 1399 --GIKGDKGPPGGKGQP-GDPGIPGHKGHTGLM----GPQGLPGENGPVGPPGPPGQPGF 1451

Query: 953  -GMRFEGPHGQSVAGLRFEGQHNQLGGNLRF-------------------EGPHGQPGVG 992
             G+R E P  +++  L  E    QL   L +                    GP G+ G+ 
Sbjct: 1452 PGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLP 1511

Query: 993  IRFEGPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALR----FDGQPGQP 1046
             R  GP+ + G  G    EGPS P G     G  G  G    G           GQPG+P
Sbjct: 1512 GR-AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEP 1570

Query: 1047 SLLPRFDGLHGQPGPRFERTP-GQPGPQRFDGPPGQ 1081
                  DGL G PGP+ E  P G PG     GPPGQ
Sbjct: 1571 GYAK--DGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 128/442 (28%), Positives = 166/442 (37%), Gaps = 61/442 (13%)

Query: 754  GPSRPSVAR--DGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQG 811
            GP+ P  A+  +G         N  +P   G P P+     G PG +G  G     G  G
Sbjct: 895  GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPS-----GPPGSVGAPGLRGTPGKDG 949

Query: 812  QLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQ 871
            + G       EG PGPVG P    G  G  G  G   +G PGLR  GSPG     GP G 
Sbjct: 950  ERGEKGAAGEEGSPGPVG-PRGDPGAPGLPGPPGKGKDGEPGLR--GSPG---LPGPLGT 1003

Query: 872  PVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFD 931
                 +  G     +GG   +G  G P G       RG P  G+   G  GPSG      
Sbjct: 1004 KAACGKVRGSENCALGGQCVKGDRGAP-GIPGSPGSRGDP--GIGVAGPPGPSGPP---- 1056

Query: 932  GPHGQPG--GGIRFEGPLLQQGVGMRF--------EGPHGQ-SVAGLRFEGQHNQLGGNL 980
            G  G PG  G   F GP   QG   R          GP G+  ++ L   G  N L  ++
Sbjct: 1057 GDKGSPGSRGLPGFPGP---QGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDV 1113

Query: 981  RFEGPHGQPGV----GIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHA 1036
              + P G PG+    G + +  +  + G    EG     G   + GP G  GP+      
Sbjct: 1114 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ------ 1167

Query: 1037 LRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDG 1096
                G  G+       DG  GQ G +     G PG   F GPPG    P  DG+      
Sbjct: 1168 ----GSQGERGA----DGEVGQKGDQ-----GHPGVPGFMGPPGNPGPPGADGIAGAAGP 1214

Query: 1097 PQHQQASRFDIPLGLQG-TRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRH 1155
            P  Q +   + P G QG +     P +  +     + GP  + PG A      G +  R 
Sbjct: 1215 PGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGE-PGKAGEPGLPGPEGARG 1273

Query: 1156 EQIFDSPQGPNFNGPHGPGNQS 1177
               F    G   +G  GP  +S
Sbjct: 1274 PPGFKGHTGD--SGAPGPRGES 1293



 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 152/541 (28%), Positives = 192/541 (35%), Gaps = 119/541 (21%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P + GPP P      G PG++G  G     GP G  G   P    GPPGP GT    +G 
Sbjct: 719  PGVPGPPGPGGS--PGLPGEIGFPGKPGPPGPTGPPGKDGP---NGPPGPPGT----KGE 769

Query: 838  IGQAGGGGFRFEGSPGLRFEGSPGGLRF----EGPGGQPVGGLRFEGHRGQPVGGLRFEG 893
             G+ G  G    G PGLR E    GL      +G  G P G   F G RG+  G    +G
Sbjct: 770  PGERGEDGL--PGKPGLRGEIGEQGLAGRPGEKGEAGLP-GAPGFPGVRGEK-GDQGEKG 825

Query: 894  PHGQPVGGLRFDN-------PRGQPVGGL-----------RFEGGHGPSGAAIRFDGPHG 935
              G P  GL+ D        P G P  GL           R  G  GP G      G  G
Sbjct: 826  ELGLP--GLKGDRGEKGEAGPAGPP--GLPGTTSLFTPHPRMPGEQGPKGEK-GDPGLPG 880

Query: 936  QPG-----GGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLG--------GNLRF 982
            +PG     G +  +GP    G   + EG HG   A     G    +G        G++  
Sbjct: 881  EPGLQGRPGELGPQGPTGPPGAKGQ-EGAHGAPGAAGN-PGAPGHVGAPGPSGPPGSVGA 938

Query: 983  EGPHGQPGV-GIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDG 1041
             G  G PG  G R E     + G     GP    G   + GP G+G    +G   LR  G
Sbjct: 939  PGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGK---DGEPGLR--G 993

Query: 1042 QPGQPSLLPR-------------------------FDGLHGQPGPRFERTPGQPGPQRFD 1076
             PG P  L                             G+ G PG R +   G  GP    
Sbjct: 994  SPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPS 1053

Query: 1077 GPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYN 1136
            GPPG +  P   G+P  F GPQ         P G  G     +P +R         GP  
Sbjct: 1054 GPPGDKGSPGSRGLP-GFPGPQG--------PAGRDGA--PGNPGER---------GPPG 1093

Query: 1137 DPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQSFSNPLNRASGHYFDEKNLQ 1196
             P  ++  +P   +     +   D P GP    P  PG   F            +    +
Sbjct: 1094 KPGLSSLLSPGD-INLLAKDVCNDCPPGP----PGLPGLPGFKGDKGVPGKPGREGTEGK 1148

Query: 1197 SSQFGNFGNIPAPMTVGNIQASQQVLSGVAQPVAFGQ-GQQFLPVHPQNPGFVQNPSGAL 1255
              + G  G +P P  +   Q SQ       +  A G+ GQ+    HP  PGF+  P    
Sbjct: 1149 KGEAGPPG-LPGPPGIAGPQGSQ------GERGADGEVGQKGDQGHPGVPGFMGPPGNPG 1201

Query: 1256 P 1256
            P
Sbjct: 1202 P 1202



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 117/399 (29%), Positives = 141/399 (35%), Gaps = 114/399 (28%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P + GPP  A  +  GS G+ G  G +  +G QG    G P  F GPPG  G P   +G 
Sbjct: 1155 PGLPGPPGIAGPQ--GSQGERGADGEVGQKGDQGH--PGVP-GFMGPPGNPGPP-GADGI 1208

Query: 838  IGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQP--VGGLRFEGHRGQPVGGLRFEGPH 895
             G AG  G   +GSPG   EG PG    +GP G P   G    EG  G+P       GP 
Sbjct: 1209 AGAAGPPGI--QGSPGK--EGPPGP---QGPSGLPGIPGEEGKEGRDGKP-------GPP 1254

Query: 896  GQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMR 955
            G+P          G+P       G  GP GA        G PG    F+G     G    
Sbjct: 1255 GEP-------GKAGEP-------GLPGPEGA-------RGPPG----FKGHTGDSGA--- 1286

Query: 956  FEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPG 1015
              GP G+S              G +   G  G PG          + G      GP+ P 
Sbjct: 1287 -PGPRGES--------------GAMGLPGQEGLPG----------KDGD----TGPTGPQ 1317

Query: 1016 GGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRF 1075
            G     GP G+ G            G PG+P       G  GQ G + E   G PG   F
Sbjct: 1318 GPQGPRGPPGKNGS----------PGSPGEPGP----SGTPGQKGSKGEN--GSPGLPGF 1361

Query: 1076 DGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPY 1135
             GP G   +P   GVP +   P       F    G  G + D                  
Sbjct: 1362 LGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGD------------------ 1403

Query: 1136 NDPPGNAFNAPSQGLQFQRHEQIFDSPQG-PNFNGPHGP 1173
              PPG        G+   +       PQG P  NGP GP
Sbjct: 1404 KGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP 1442



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 47/161 (29%), Positives = 66/161 (40%), Gaps = 24/161 (14%)

Query: 978  GNLRFEGPHGQPGVGIRFEGPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCH 1035
            G +   GP G PG       P    G  G +   GP    G + I GP GQG    +G  
Sbjct: 484  GEMGVAGPMGLPG-------PKGDIGAIGPVGAPGPKGEKGDVGI-GPFGQGEKGEKG-- 533

Query: 1036 ALRFDGQPGQPSLLPRFDGLHGQPGPRFER-TPGQPGPQRFDGPPGQQVQPRFDGVPQRF 1094
            +L   G PG+        G+ G+PG   E   PG+ G +   GPPG    P   G P   
Sbjct: 534  SLGLPGPPGRDGS----KGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAP-GL 588

Query: 1095 DGPQHQQASRFDIPLGLQGTR-FDNHPSQRLESVSFNQTGP 1134
             G + ++ +R     G +G R  D  P +  ++    + GP
Sbjct: 589  QGERGEKGTR-----GEKGERGLDGFPGKPGDTGQQGRPGP 624


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 97.4 bits (241), Expect = 9e-20
 Identities = 144/439 (32%), Positives = 175/439 (39%), Gaps = 87/439 (19%)

Query: 753  DGPSRPSVA-------RDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLR 805
            DG SRP  A       + G    +   P  + P   GP  P  L+     GQ GG GP  
Sbjct: 185  DGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPV--GPRGPQGLQ-----GQQGGAGPTG 237

Query: 806  FEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPG-LRFEGSPGGLR 864
              G  G  G   P+   GP GP G P    G  G+ G       G+PG + F GSPG   
Sbjct: 238  PPGEPGDPGPMGPIGSRGPEGPPGKP----GEDGEPGR-----NGNPGEVGFAGSPGARG 288

Query: 865  FEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPS 924
            F G  G P  GL+  GHRG    GL  EGP G+              VG    +G  GP+
Sbjct: 289  FPGAPGLP--GLK--GHRGHK--GL--EGPKGE--------------VGAPGSKGEAGPT 326

Query: 925  G--AAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRF 982
            G   A+   GP G PG   R  GP  Q   G R  G HG         G+   + G L  
Sbjct: 327  GPMGAMGPLGPRGMPGERGRL-GP--QGAPGQR--GAHG-------MPGKPGPM-GPLGI 373

Query: 983  EGPHGQPG-VGIRFE-GPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFD 1040
             G  G PG  G++ E GP   +G     EGP    G     GP+  G P   G  A+  D
Sbjct: 374  PGSSGFPGNPGMKGEAGPTGARGP----EGPQGQRGETGPPGPV--GSPGLPG--AIGTD 425

Query: 1041 GQPGQ--PSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVP--QRFDG 1096
            G PG   P+  P   G  G  GP     PG PGPQ   GP G + QP   GVP  +   G
Sbjct: 426  GTPGAKGPTGSPGTSGPPGSAGP-----PGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAG 480

Query: 1097 PQHQQASR-FDIPLGLQGTRFDNHPSQRLESVSFNQTGPYND--PPGNAFNAPSQGLQFQ 1153
            P+ +        P+G  G      P  R +  +    GP  +   PGN     S GL   
Sbjct: 481  PKGEPGPHGIQGPIGPPGEEGKRGP--RGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGP 538

Query: 1154 RHEQIFDSPQGPNFNGPHG 1172
            +  Q    P G   +GP G
Sbjct: 539  KGAQGERGPVGS--SGPKG 555



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 111/324 (34%), Positives = 132/324 (40%), Gaps = 51/324 (15%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P   GP  P   R  G+PG+ G  G     G +G  GG  P   +G PGP GTP    GP
Sbjct: 701  PGAVGPLGPRGER--GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTP-GDTGP 757

Query: 838  IGQAGGGGFR-FEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHG 896
             G  G  G R   G+PG +  G  GG+  +G  G        +G RG P G L   GP G
Sbjct: 758  PGLQGMPGERGIAGTPGPK--GDRGGIGEKGAEGTAGN----DGARGLP-GPLGPPGPAG 810

Query: 897  QPVGGLRFDNPRG--QPVGGLRFEGGHGPSG--AAIRFDGPHGQPG-GGIRFEGPLLQQG 951
             P G      PRG   P G     G  G +G   A+ F GP G  G  G++ E     Q 
Sbjct: 811  -PTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQK 869

Query: 952  VGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGV--GIRFEGPLVQQG--GGMR 1007
                  GP G              L G+    GP+G PG+  G   +GP    G  G   
Sbjct: 870  GDAGSPGPQG--------------LAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAG 915

Query: 1008 FEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTP 1067
              GP  P G     GPLG+ G   EG   LR  G PG    +    G  G  GP     P
Sbjct: 916  RVGPPGPAGAPGPAGPLGEPGK--EGPPGLR--GDPGSHGRV----GDRGPAGP-----P 962

Query: 1068 GQPGPQRFDGPPGQQVQPRFDGVP 1091
            G PG +   G PG+  QP  DG P
Sbjct: 963  GGPGDK---GDPGEDGQPGPDGPP 983



 Score = 84.7 bits (208), Expect = 6e-16
 Identities = 122/359 (33%), Positives = 141/359 (39%), Gaps = 81/359 (22%)

Query: 754  GPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFD-GSPGQMGGGGPLRFEGPQGQ 812
            GP  P+ A  GP   + E      P  +GPP    LR D GS G++G  GP    GP G 
Sbjct: 918  GPPGPAGA-PGPAGPLGE------PGKEGPP---GLRGDPGSHGRVGDRGPA---GPPGG 964

Query: 813  LGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFE-GSPGGLRFEGPGGQ 871
             G       +G PGP G P    GP G  G  G    G PG R E G PG     GP G 
Sbjct: 965  PGDKGDPGEDGQPGPDGPP----GPAGTTGQRGI--VGMPGQRGERGMPG---LPGPAGT 1015

Query: 872  P--VGGLRFEGHRGQP--VGGLRFEGPHGQP--VGGLRFDNPRGQP--VGGLRFEGGHGP 923
            P  VG     G +G P  VG     GP G+P   G    D   G+   VG     G  GP
Sbjct: 1016 PGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGP 1075

Query: 924  SG-----AAIRFDGPHGQPG-----GGIRFEGPLLQQG-VGMRF----EGPHGQSVAGLR 968
            +G      A    GP G PG     G     GP+   G  G R     +GP G       
Sbjct: 1076 AGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGD------ 1129

Query: 969  FEGQHNQLG-----GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGP 1023
             +G H   G     G+  F G  G PG      GP  +QG      GP  P G     GP
Sbjct: 1130 -KGDHGDRGDRGQKGHRGFTGLQGLPGP----PGPNGEQGSA-GIPGPFGPRGP---PGP 1180

Query: 1024 LGQGGPRFEGCHALRFDGQPGQ--PSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPG 1080
            +G  G           +G PG   P   P   G  G+ GP  E  PG+PGP    GPPG
Sbjct: 1181 VGPSGK----------EGNPGPLGPIGPPGVRGSVGEAGP--EGPPGEPGPPGPPGPPG 1227



 Score = 84.3 bits (207), Expect = 8e-16
 Identities = 108/328 (32%), Positives = 126/328 (38%), Gaps = 52/328 (15%)

Query: 782  GPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQA 841
            GPP PA     G  G+ G  GP    GP G  G        GP G VG    F GP G  
Sbjct: 804  GPPGPA-----GPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVG----FAGPQGPD 854

Query: 842  GGGGFRFE-GSPGLRFE-GSPGGLRFEGPGGQ--PVGGLRFEGHRGQ--PVGGLRFEGPH 895
            G  G + E G PG + + GSPG     G  G   P G    +G RG   P G   F G  
Sbjct: 855  GQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSA 914

Query: 896  GQ-----PVGGLRFDNPRGQP----VGGLRFE-GGHGPSGAAIRFDGPHGQPGGGIRFEG 945
            G+     P G      P G+P      GLR + G HG  G      GP G PGG      
Sbjct: 915  GRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDR----GPAGPPGGPGDKGD 970

Query: 946  PLLQQGVGMRFEGPHGQS-VAGLR-FEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQ 1001
            P      G   +GP G +   G R   G   Q G  G     GP G PG         V 
Sbjct: 971  PGEDGQPGP--DGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK--------VG 1020

Query: 1002 QGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGP 1061
              G    +GP  P G     GP+G+ GP     +    DG PG+   +    G  G PGP
Sbjct: 1021 PTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN----DGTPGRDGAVGE-RGDRGDPGP 1075

Query: 1062 R----FERTPGQPGPQRFDGPPGQQVQP 1085
                  +  PG PGP    G  GQ+  P
Sbjct: 1076 AGLPGSQGAPGTPGPVGAPGDAGQRGDP 1103



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 123/411 (29%), Positives = 164/411 (39%), Gaps = 76/411 (18%)

Query: 793  GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFR-FEGS 851
            G PG  G  GP+   GP G+ G   P    G PG VG P    GP+G+ G  G R F GS
Sbjct: 483  GEPGPHGIQGPI---GPPGEEGKRGP---RGDPGTVGPP----GPVGERGAPGNRGFPGS 532

Query: 852  PGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP--VGGLRFEGPHGQPVGGLRFDNPRG 909
             GL     PG    +G  G PVG    +G +G P   G     G  G   G      P G
Sbjct: 533  DGL-----PGPKGAQGERG-PVGSSGPKGSQGDPGRPGEPGLPGARGL-TGNPGVQGPEG 585

Query: 910  Q--PVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGL 967
            +  P+G    +G  GP G+     G  GQP G +   GP    G   +        V G 
Sbjct: 586  KLGPLGAPGEDGRPGPPGSI----GIRGQP-GSMGLPGPKGSSGDPGKPGEAGNAGVPGQ 640

Query: 968  R-FEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG--GGMRFEG----PSVPGGGLR- 1019
            R   G+  ++G +    GP G PG+     G   +QG  G   F+G    P  PG G + 
Sbjct: 641  RGAPGKDGEVGPS----GPVGPPGLA----GERGEQGPPGPTGFQGLPGPPGPPGEGGKP 692

Query: 1020 -------IEGPLGQGGPRFEGCHALRFDGQPGQPSL--LPRFDGL---HGQPGPRFERTP 1067
                     G +G  GPR E  +     G+ G+P +  LP   G+   HG  GP+   +P
Sbjct: 693  GDQGVPGDPGAVGPLGPRGERGN----PGERGEPGITGLPGEKGMAGGHGPDGPK--GSP 746

Query: 1068 GQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDN--------- 1118
            G  G     GPPG Q  P   G+     GP+  +    +   G +GT  ++         
Sbjct: 747  GPSGTPGDTGPPGLQGMPGERGIAGT-PGPKGDRGGIGE--KGAEGTAGNDGARGLPGPL 803

Query: 1119 -HPSQRLESVSFNQTGPYN--DPPGNAFNAPSQGLQFQRHEQIFDSPQGPN 1166
              P     +    + GP     PPG+  N  S+G         F  PQGP+
Sbjct: 804  GPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPD 854



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 140/446 (31%), Positives = 163/446 (36%), Gaps = 86/446 (19%)

Query: 754  GPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQL 813
            GP      R  P  M   GP   S     P  P      G PGQ G  G     GP G +
Sbjct: 600  GPPGSIGIRGQPGSMGLPGPKGSS---GDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPV 656

Query: 814  G--GGCPLRFE-GPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGG 870
            G  G    R E GPPGP G      GP G  G G     G PG   +G PG      PG 
Sbjct: 657  GPPGLAGERGEQGPPGPTGFQ-GLPGPPGPPGEG-----GKPG--DQGVPG-----DPGA 703

Query: 871  QPVGGLRFEGHRGQPVGGLRFEGPHGQP-VGGLRFDNPRGQPVGGLRFEGGHGPSGAAIR 929
              VG L   G RG P       G  G+P + GL          G     GGHGP G    
Sbjct: 704  --VGPLGPRGERGNP-------GERGEPGITGL---------PGEKGMAGGHGPDGPK-G 744

Query: 930  FDGPHGQPG--GGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLG--GNLRFEGP 985
              GP G PG  G    +G   ++G+     GP G    G+  +G     G  G     GP
Sbjct: 745  SPGPSGTPGDTGPPGLQGMPGERGIA-GTPGPKGDR-GGIGEKGAEGTAGNDGARGLPGP 802

Query: 986  HGQPG----VGIRFE-------GPLVQQGG-GMRFE-GPSVPGGGLRIEGPLGQGGPRFE 1032
             G PG     G + E       GP   +G  G R E GP+   G    +GP GQ G + E
Sbjct: 803  LGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGE 862

Query: 1033 GCHALRFDGQPGQ--PSLLPRFDGLHGQPGPRFER-TPGQPGPQRFDGPPGQQVQPRFDG 1089
                    G+PGQ   +  P   GL G PGP      PG  G +   GPPG      F G
Sbjct: 863  -------PGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPG---ATGFPG 912

Query: 1090 VPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYN--DPPGNAFNAPS 1147
               R   P    A     PLG  G   +  P  R +  S  + G      PPG   +   
Sbjct: 913  SAGRVGPPGPAGAPGPAGPLGEPGK--EGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGD 970

Query: 1148 QGLQFQRHEQIFDSPQGPNFNGPHGP 1173
             G          D   GP  +GP GP
Sbjct: 971  PG---------EDGQPGP--DGPPGP 985



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 134/449 (29%), Positives = 161/449 (35%), Gaps = 111/449 (24%)

Query: 775  KLSPRID----GPPTPASLRFD----GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPG 826
            K  PR D    GPP P   R      G PG  G  GP   +G +G +G   P   +G PG
Sbjct: 502  KRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPG 561

Query: 827  PVGTP-----------LRFEGPIGQAGGGGFRFE-GSPG----LRFEGSPGGLRFEGPGG 870
              G P              +GP G+ G  G   E G PG    +   G PG +   GP G
Sbjct: 562  RPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKG 621

Query: 871  Q--------PVGGLRFEGHRGQP--VGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGG 920
                       G     G RG P   G +   GP G P  GL  +     P G   F+G 
Sbjct: 622  SSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPP--GLAGERGEQGPPGPTGFQGL 679

Query: 921  HGPSGAAIRFDGPHGQPG-----GGIRFEGPLLQQGVGMRFEGPHGQ-SVAGLRFEGQHN 974
             GP G      G  G+PG     G     GPL  +G      G  G+  + GL   G+  
Sbjct: 680  PGPPGP----PGEGGKPGDQGVPGDPGAVGPLGPRGERGN-PGERGEPGITGL--PGEKG 732

Query: 975  QLGGNLRFEGPHGQPGVG--IRFEGPLVQQG-----GGMRFEGPSVPGGGLRIEGPLGQG 1027
              GG+   +GP G PG        GP   QG     G     GP    GG+  +G  G  
Sbjct: 733  MAGGH-GPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTA 791

Query: 1028 GPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRF 1087
            G           DG  G P  L    G  G  GP  E+  G+PGP+   GPPG +  P  
Sbjct: 792  GN----------DGARGLPGPL----GPPGPAGPTGEK--GEPGPRGLVGPPGSRGNPGS 835

Query: 1088 DGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDP--PGNAFNA 1145
             G     +GP    A  F  P G  G                 Q G   +P  PG   +A
Sbjct: 836  RGE----NGP--TGAVGFAGPQGPDG-----------------QPGVKGEPGEPGQKGDA 872

Query: 1146 PSQGLQFQRHEQIFDSPQG-PNFNGPHGP 1173
             S G            PQG     GPHGP
Sbjct: 873  GSPG------------PQGLAGSPGPHGP 889



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 135/443 (30%), Positives = 158/443 (35%), Gaps = 103/443 (23%)

Query: 772  GPNKL--SPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVG 829
            GP  L  SP   GP        +G PG  GG G    +GP G  G        GPPGP G
Sbjct: 876  GPQGLAGSPGPHGP--------NGVPGLKGGRGT---QGPPGATGFPGSAGRVGPPGPAG 924

Query: 830  TPLRFEGPIGQAGGGGFRFEGSPGLRFE-GSPGGLRFEGPGGQPVGGLRFEGHRGQPVGG 888
             P    GP G  G  G   EG PGLR + GS G +   GP G P G     G +G P G 
Sbjct: 925  AP----GPAGPLGEPGK--EGPPGLRGDPGSHGRVGDRGPAGPPGG----PGDKGDP-GE 973

Query: 889  LRFEGPHGQP-----------VGGLRFDNPRGQP--VGGLRFEGGHGPSGAAIRFDGPHG 935
                GP G P           VG       RG P   G     G  GP+GA     G  G
Sbjct: 974  DGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGAT----GDKG 1029

Query: 936  QPG--GGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLG-----GNLRFEGPHGQ 988
             PG  G     GP+ + G     EGP G      R +G   + G     G     G  G 
Sbjct: 1030 PPGPVGPPGSNGPVGEPGP----EGPAGNDGTPGR-DGAVGERGDRGDPGPAGLPGSQGA 1084

Query: 989  PGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSL 1048
            PG      GP+   G   +   P   G      GP G+ G R          G PG    
Sbjct: 1085 PGT----PGPVGAPGDAGQRGDPGSRGP----IGPPGRAGKR----------GLPGPQG- 1125

Query: 1049 LPRFD-GLHGQPGPRFERTP-GQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFD 1106
             PR D G HG  G R ++   G  G Q   GPPG   +    G+P  F GP+        
Sbjct: 1126 -PRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPF-GPRGPPG---- 1179

Query: 1107 IPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPN 1166
             P+G  G   +  P            GP   PPG   +    G +          P  P 
Sbjct: 1180 -PVGPSGKEGNPGP-----------LGPIG-PPGVRGSVGEAGPE--------GPPGEPG 1218

Query: 1167 FNGPHGPGNQSFSNPLNRASGHY 1189
              GP GP     +  L    GHY
Sbjct: 1219 PPGPPGPPGH-LTAALGDIMGHY 1240



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 48/147 (32%), Positives = 55/147 (37%), Gaps = 23/147 (15%)

Query: 1041 GQPGQPSLLPRFDGLHGQP---------GPRFER----TPGQPGPQRFDGPPGQQVQPRF 1087
            GQ G+P L+P   G+ G+P         GPR ER     PG  GPQ  DG PG   QP  
Sbjct: 113  GQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGA 172

Query: 1088 DGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPS 1147
             G P     P H        P   Q    D       +S   +Q G      G       
Sbjct: 173  PGPPGH---PSHPGPDGLSRPFSAQMAGLDE------KSGLGSQVGLMPGSVGPVGPRGP 223

Query: 1148 QGLQFQRHEQIFDSPQG-PNFNGPHGP 1173
            QGLQ Q+       P G P   GP GP
Sbjct: 224  QGLQGQQGGAGPTGPPGEPGDPGPMGP 250


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 97.4 bits (241), Expect = 9e-20
 Identities = 122/379 (32%), Positives = 153/379 (40%), Gaps = 72/379 (18%)

Query: 755  PSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLG 814
            P  P V  +G T +  + P+   P   GPP P        PG  G  GP  ++G QG++G
Sbjct: 159  PGHPGVLPEGATDL--QCPSICPP---GPPGP--------PGMPGFKGPTGYKGEQGEVG 205

Query: 815  GGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPG-LRFEGSPGGLRFEGPGGQPV 873
                    GPPGP G P    G +G  G  G R  G PG L   G  G + F GP G P 
Sbjct: 206  KDGEKGDPGPPGPAGLP----GSVGLQGPRGLR--GLPGPLGPPGDRGPIGFRGPPGIP- 258

Query: 874  GGLRFEGHRGQ--------PVGGLRFEGPHGQP-VGGLRFDNPRGQP----------VGG 914
            G     G RG+        P G L   GP G P V G     P G+P          V G
Sbjct: 259  GAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAG-----PSGEPGMPGKDGQNGVPG 313

Query: 915  LRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGVG--MRFEGPHGQ-------S 963
            L  + G      A    GP+G PG  G    +G   ++G    +   GP G+        
Sbjct: 314  LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373

Query: 964  VAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG--GGMRFEGPSVPGGGLRIE 1021
            + G R E  H    G L  +GP G PGV   F+G   Q+G  G     GP    G +   
Sbjct: 374  MPGERGEAGHRGSAGALGPQGPPGAPGVR-GFQG---QKGSMGDPGLPGPQGLRGDVGDR 429

Query: 1022 GPLGQGGPRFEGCHALRFDGQPGQPSLL-------PRFD-GLHGQPGPRFERTP-GQPGP 1072
            GP G  GP+ +   A   DG PG    L       P+ + G  G+ GP+  + P G  G 
Sbjct: 430  GPGGAAGPKGDQGIA-GSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGV 488

Query: 1073 QRFDGPPGQQVQPRFDGVP 1091
            Q   GPPG        GVP
Sbjct: 489  QGVPGPPGPLGLQGVPGVP 507



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 128/418 (30%), Positives = 161/418 (38%), Gaps = 74/418 (17%)

Query: 793  GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSP 852
            G PG  G  GP    G  G  G   P    GPPGP G P    G  G+ G  G    G P
Sbjct: 29   GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAP----GKPGKPGEAG--LPGLP 82

Query: 853  GLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQP-VGGLRFDNPRGQ- 910
            G+  +G  G     GP G P       G RG         GP G P +GG     P G+ 
Sbjct: 83   GV--DGLTGRDGPPGPKGAP-------GERGS-------LGPPGPPGLGGKGLPGPPGEA 126

Query: 911  ----PVGGLRFEGGHGPSGAAIRFDGPHGQPG----GGIRFEGPLLQQGVGMRFEGPHG- 961
                P GG+   G  GPSG      GP G PG     G+  EG    Q   +   GP G 
Sbjct: 127  GVSGPPGGIGLRGPPGPSGLP-GLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGP 185

Query: 962  QSVAGLR----FEGQHNQLG-----GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPS 1012
              + G +    ++G+  ++G     G+    GP G PG  +  +GP   +G      GP 
Sbjct: 186  PGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPG-SVGLQGPRGLRG----LPGPL 240

Query: 1013 VPGGGLRIEGPLG-QGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPG 1071
             P G     GP+G +G P   G      D     P       G  G+PGP+   TPG  G
Sbjct: 241  GPPGD---RGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPK--GTPGVAG 295

Query: 1072 PQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDI-----PLGLQG----TRFDNHPSQ 1122
            P    G PG+  Q   +GVP   DG Q  +A R        P GL G            +
Sbjct: 296  PSGEPGMPGKDGQ---NGVP-GLDG-QKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGE 350

Query: 1123 RLESVSFNQTGPYNDP--PGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGPGNQSF 1178
            R  +    + GP  +P  PG+A     +G    R       PQGP    P  PG + F
Sbjct: 351  RGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGP----PGAPGVRGF 404



 Score = 84.3 bits (207), Expect = 8e-16
 Identities = 134/429 (31%), Positives = 166/429 (38%), Gaps = 96/429 (22%)

Query: 755  PSRPSV----ARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGP---LRFE 807
            P  P V     RDGP         + S    GPP        G PG+ G  GP   +   
Sbjct: 79   PGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLR 138

Query: 808  GPQGQLG-GGCPLRFEGPPGPVGTP-----------------LRFEGPIGQAGGGGFR-- 847
            GP G  G  G P    GPPGP G P                 +   GP G  G  GF+  
Sbjct: 139  GPPGPSGLPGLP----GPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGP 194

Query: 848  --FEGSPG-LRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQP--VGGL 902
              ++G  G +  +G  G     GP G P G +  +G RG  + GL   GP G P   G +
Sbjct: 195  TGYKGEQGEVGKDGEKGDPGPPGPAGLP-GSVGLQGPRG--LRGL--PGPLGPPGDRGPI 249

Query: 903  RFDNPRGQP--VGGLRFEGGHGPSGAAIRFDGPHGQ-----PGGGIRFEGPLLQQGVGMR 955
             F  P G P   G     G  GP G    F GP G      P G     GP  + G+   
Sbjct: 250  GFRGPPGIPGAPGKAGDRGERGPEG----FRGPKGDLGRPGPKGTPGVAGPSGEPGM--- 302

Query: 956  FEGPHGQS-VAGLRFEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQG--GGMRFEG 1010
              G  GQ+ V GL  +GQ  + G  G    +GP+G PG+  R  G   ++G  G     G
Sbjct: 303  -PGKDGQNGVPGL--DGQKGEAGRNGAPGEKGPNGLPGLPGR-AGSKGEKGERGRAGELG 358

Query: 1011 PSVPGGGLRIEGPLGQGGPRFEGCH-----ALRFDGQPGQPSLLPRFDGLHGQPGPRFER 1065
             + P G   + G  G  G R E  H     AL   G PG P +     G  GQ G   + 
Sbjct: 359  EAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGV----RGFQGQKGSMGD- 413

Query: 1066 TPGQPGPQ--RFD----------GPPGQQVQPRFDGV--------PQRFDGPQHQQASRF 1105
             PG PGPQ  R D          GP G Q     DG+        P    GP+ +  SR 
Sbjct: 414  -PGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRG 472

Query: 1106 DI-PLGLQG 1113
            ++ P G QG
Sbjct: 473  ELGPKGTQG 481



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 131/430 (30%), Positives = 155/430 (36%), Gaps = 114/430 (26%)

Query: 782  GPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQA 841
            GPP PA L   GS G  G  G     GP G  G   P+ F GPPG  G P +  G  G+ 
Sbjct: 214  GPPGPAGL--PGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGK-AGDRGER 270

Query: 842  GGGGFRFE----GSPGLRFEGSPGGLRFEGPGGQP----------VGGLRFEGHRGQPV- 886
            G  GFR      G PG +  G+PG     GP G+P          V GL  +G +G+   
Sbjct: 271  GPEGFRGPKGDLGRPGPK--GTPG---VAGPSGEPGMPGKDGQNGVPGL--DGQKGEAGR 323

Query: 887  -GGLRFEGPHGQP-----------------VGGLRFDNPRGQP-------VGGLRFEGGH 921
             G    +GP+G P                  G L    P G+P       + G R E GH
Sbjct: 324  NGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGH 383

Query: 922  GPSGAAIRFDGPHGQPG-----------GGIRFEGPL-LQQGVGMR----FEGPHG-QSV 964
              S  A+   GP G PG           G     GP  L+  VG R      GP G Q +
Sbjct: 384  RGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGI 443

Query: 965  AGLR-FEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGP 1023
            AG     G   +LG +    GP G+ G      GP   QG         VPG      GP
Sbjct: 444  AGSDGLPGDKGELGPS-GLVGPKGESGSRGEL-GPKGTQGPNGTSGVQGVPGP----PGP 497

Query: 1024 LG-QGGPRFEGCHALRFDGQPGQPSL---------------------------LPRFDGL 1055
            LG QG P   G       G+PG P                              P   G 
Sbjct: 498  LGLQGVPGVPG-----ITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGS 552

Query: 1056 HGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRF--DGPQHQQASRFD---IPLG 1110
             G+PGP     PG PGP    G PG +  P + G        GP+  Q  R D      G
Sbjct: 553  IGRPGPA--GPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAG 610

Query: 1111 LQGTRFDNHP 1120
            L G   D  P
Sbjct: 611  LDGPEGDQGP 620



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 97/332 (29%), Positives = 118/332 (35%), Gaps = 61/332 (18%)

Query: 793  GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE--- 849
            G PG+ G  G     G  G+LG   P    G PG  G P    G  G  G  G       
Sbjct: 337  GLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGE-RGEAGHRGSAGALGPQGP 395

Query: 850  -GSPGLR-FEGSPGGLRFEG-PGGQPVGGL---RFEGHRGQPVGGLRFEGPHGQP----- 898
             G+PG+R F+G  G +   G PG Q + G    R  G    P G     G  G P     
Sbjct: 396  PGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGE 455

Query: 899  VGGLRFDNPRGQPV--GGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGV---- 952
            +G      P+G+    G L  +G  GP+G +    G  G PG      GPL  QGV    
Sbjct: 456  LGPSGLVGPKGESGSRGELGPKGTQGPNGTS----GVQGVPGP----PGPLGLQGVPGVP 507

Query: 953  ---------GMRFEGPHGQSVAGLRFEGQHNQLGGNLR---FEGPHGQPGVGIRFEGPLV 1000
                     G        + + G     Q  QL  +LR     G  G+PG      GP  
Sbjct: 508  GITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPA----GPPG 563

Query: 1001 QQG--GGMRFEGPSVPGGGLRIEGPLGQGGPRF-------EGCHALRFDGQPGQPSLLPR 1051
              G  G +   G   P G     G LG  GPR        +G      DG  G       
Sbjct: 564  PPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGP--- 620

Query: 1052 FDGLHGQPGPRFER---TPGQPGPQRFDGPPG 1080
              G  G PG   +     PG+PGP    G PG
Sbjct: 621  -QGPQGVPGTSKDGQDGAPGEPGPPGDPGLPG 651



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 42/125 (33%), Positives = 50/125 (40%), Gaps = 24/125 (19%)

Query: 749 RPLFDGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEG 808
           +PL  G    S+ R GP      GP        GPP P      GS G  G  GP  + G
Sbjct: 546 KPLAPG----SIGRPGPA-----GP-------PGPPGPP-----GSIGHPGARGPPGYRG 584

Query: 809 PQGQLGGGCPLRFEGPPGPVGTP-LRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEG 867
           P G+LG   P   +G  G  G      +GP G  G  G   +G PG   +G  G     G
Sbjct: 585 PTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQG--PQGVPGTSKDGQDGAPGEPG 642

Query: 868 PGGQP 872
           P G P
Sbjct: 643 PPGDP 647



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 42/131 (32%), Positives = 53/131 (40%), Gaps = 15/131 (11%)

Query: 768 MIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGP 827
           MI E   +L+  +  P  P S+   G  G  G  GP    G  G  G   P  + GP G 
Sbjct: 532 MISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGP---PGSIGHPGARGPPGYRGPTGE 588

Query: 828 VGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVG 887
           +G P    GP G  G  G +  G+ G   +G  G    +GP G P  G   +G  G P  
Sbjct: 589 LGDP----GPRGNQGDRGDK--GAAGAGLDGPEGDQGPQGPQGVP--GTSKDGQDGAP-- 638

Query: 888 GLRFEGPHGQP 898
                GP G P
Sbjct: 639 --GEPGPPGDP 647


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 124/561 (22%), Positives = 234/561 (41%), Gaps = 90/561 (16%)

Query: 138 VNSLDPAWPIKPLPPNVNTSSIHVNPKFLNKSPEEPSTPGTVVSSPSISTPPIVPDIQK- 196
           + SL P   + P+P     +++ V+   L   P     P  + +   I  PP++ ++   
Sbjct: 117 MTSLMPGAGLLPIPTPNPLTTLGVSLSSLGAIPAAALDPN-IATLGEIPQPPLMGNVDPS 175

Query: 197 ------------NLTQEQLIRQQLLAKQKQLLELQQKKLELELEQ----AKAQLAVSLSV 240
                       NL  +     QLL   KQ+ E++  ++  +  Q    A  + A   SV
Sbjct: 176 KIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSV 235

Query: 241 QQETSNLGPGSAPSKLHVSQIPPMAVKAPHQVPVQSEKSRPGPSLQIQDLKG---TNRDP 297
            +  +  G       L ++      VK P   P  + K       ++++ +       +P
Sbjct: 236 PRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEP 295

Query: 298 RLNRISQHSHGKDQSHRKEFLMNTLNQSDTKTSKTIPSEKLNSSKQEKSKSGEKITKKEL 357
              + ++   G+ +SH +         S +++S    S +  S  + +S+S  +   ++ 
Sbjct: 296 ESGKSNERKGGRSRSHTR---------SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK 346

Query: 358 DQLDSKS----------KSKSKSPSPLKNKLSHTKDLKNQESESMRLSDMNKRDPRLKKH 407
           D+  SKS          + KS+S S  ++K   T++ K +E E ++  D  K   R K+ 
Sbjct: 347 DRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTRE-KIKEKERVKEKDREKEREREKER 405

Query: 408 LQDKTDGKDDDVKEKRKTAEKKDKD---EHMKSSEHRLAGSRNKIINGIVQKQDTITEES 464
            ++K  GK+ D  ++R+   +KDK+   E  +  EH     + K      +K+    +E 
Sbjct: 406 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK------EKEQDKEKER 459

Query: 465 EKQGTKPGRSSTRKRSRSRSPKSRSPIIHSPKRRDRRS--PKRRQRSMSPTSTPKAGKIR 522
           EK  +K      +K  +SR+P    P  ++  RR R S   +RR+RS S + +P+  K  
Sbjct: 460 EKDRSKEIDEKRKKDKKSRTP----PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT- 514

Query: 523 QSGAKQSHMEEFTPPSREDRNAKRSTKQDIRDPRRMKKTEEERPQETTNQHSTKSGTEPK 582
               K+      +P SR  ++ KR  ++D    RR    E ER   +T+   + +  + K
Sbjct: 515 ---IKRKSSRSPSPRSRNKKDKKREKERDHISERR----ERER---STSMRKSSNDRDGK 564

Query: 583 ENVENWQSSKSAKRWKSGWEENKSLQQVDEHSKPPHLRHRESWSSTKGILSPRAPKQQQH 642
           E +E   +S   K                EH+K P        S +K +    AP+ +++
Sbjct: 565 EKLEKNSTSLKEK----------------EHNKEP------DSSVSKEVDDKDAPRTEEN 602

Query: 643 RLSVDANLQIPKELTLASKRE 663
           ++  + N Q+ +E  L++K E
Sbjct: 603 KIQHNGNCQLNEE-NLSTKTE 622


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 124/561 (22%), Positives = 234/561 (41%), Gaps = 90/561 (16%)

Query: 138 VNSLDPAWPIKPLPPNVNTSSIHVNPKFLNKSPEEPSTPGTVVSSPSISTPPIVPDIQK- 196
           + SL P   + P+P     +++ V+   L   P     P  + +   I  PP++ ++   
Sbjct: 1   MTSLMPGAGLLPIPTPNPLTTLGVSLSSLGAIPAAALDPN-IATLGEIPQPPLMGNVDPS 59

Query: 197 ------------NLTQEQLIRQQLLAKQKQLLELQQKKLELELEQ----AKAQLAVSLSV 240
                       NL  +     QLL   KQ+ E++  ++  +  Q    A  + A   SV
Sbjct: 60  KIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSV 119

Query: 241 QQETSNLGPGSAPSKLHVSQIPPMAVKAPHQVPVQSEKSRPGPSLQIQDLKG---TNRDP 297
            +  +  G       L ++      VK P   P  + K       ++++ +       +P
Sbjct: 120 PRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEP 179

Query: 298 RLNRISQHSHGKDQSHRKEFLMNTLNQSDTKTSKTIPSEKLNSSKQEKSKSGEKITKKEL 357
              + ++   G+ +SH +         S +++S    S +  S  + +S+S  +   ++ 
Sbjct: 180 ESGKSNERKGGRSRSHTR---------SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK 230

Query: 358 DQLDSKS----------KSKSKSPSPLKNKLSHTKDLKNQESESMRLSDMNKRDPRLKKH 407
           D+  SKS          + KS+S S  ++K   T++ K +E E ++  D  K   R K+ 
Sbjct: 231 DRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTRE-KIKEKERVKEKDREKEREREKER 289

Query: 408 LQDKTDGKDDDVKEKRKTAEKKDKD---EHMKSSEHRLAGSRNKIINGIVQKQDTITEES 464
            ++K  GK+ D  ++R+   +KDK+   E  +  EH     + K      +K+    +E 
Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK------EKEQDKEKER 343

Query: 465 EKQGTKPGRSSTRKRSRSRSPKSRSPIIHSPKRRDRRS--PKRRQRSMSPTSTPKAGKIR 522
           EK  +K      +K  +SR+P    P  ++  RR R S   +RR+RS S + +P+  K  
Sbjct: 344 EKDRSKEIDEKRKKDKKSRTP----PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT- 398

Query: 523 QSGAKQSHMEEFTPPSREDRNAKRSTKQDIRDPRRMKKTEEERPQETTNQHSTKSGTEPK 582
               K+      +P SR  ++ KR  ++D    RR    E ER   +T+   + +  + K
Sbjct: 399 ---IKRKSSRSPSPRSRNKKDKKREKERDHISERR----ERER---STSMRKSSNDRDGK 448

Query: 583 ENVENWQSSKSAKRWKSGWEENKSLQQVDEHSKPPHLRHRESWSSTKGILSPRAPKQQQH 642
           E +E   +S   K                EH+K P        S +K +    AP+ +++
Sbjct: 449 EKLEKNSTSLKEK----------------EHNKEP------DSSVSKEVDDKDAPRTEEN 486

Query: 643 RLSVDANLQIPKELTLASKRE 663
           ++  + N Q+ +E  L++K E
Sbjct: 487 KIQHNGNCQLNEE-NLSTKTE 506


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 140/413 (33%), Positives = 173/413 (41%), Gaps = 79/413 (19%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P + G   P  L  DG+PG++G  GP    G  G LG   P+ + GP G  G      G 
Sbjct: 792  PGVFGERGPPGL--DGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKG----LMGS 845

Query: 838  IGQAGGGGFRFE-GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHG 896
            +G+ G  G + E G PG+   G PG    +G  G P     F G RG+P       GP G
Sbjct: 846  VGEPGLKGDKGEQGVPGV--SGDPGFQGDKGSQGLP----GFPGARGKP-------GPLG 892

Query: 897  Q--PVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGV 952
            +    G + F  P G P G   F G  GP G     +GP G  G  G     GP  Q G 
Sbjct: 893  KVGDKGSIGFPGPPG-PEG---FPGDIGPPGD----NGPEGMKGKPGARGLPGPRGQLG- 943

Query: 953  GMRFEGPHGQSVA-GLRFEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFE 1009
                EGP G   A GL  EGQ  + G  G    +G  G+PG   R  GP+ +Q G M F 
Sbjct: 944  PEGDEGPMGPPGAPGL--EGQPGRKGFPGRPGLDGVKGEPGDPGR-PGPVGEQ-GFMGFI 999

Query: 1010 GPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPG-PRFERTPG 1068
            G     G +  +G  G  GP             PG P   P+  G  G PG P    TPG
Sbjct: 1000 GLVGEPGIVGEKGDRGMMGP-------------PGVPG--PK--GSMGHPGMPGGMGTPG 1042

Query: 1069 QPGPQRFDGPPGQQVQPRFDGV-----PQRFDGPQHQQASR-FDIPLGLQGTRFDNHPSQ 1122
            +PGPQ   GPPG +  P   G      P+  DGP  +Q SR    P G QG      P Q
Sbjct: 1043 EPGPQ---GPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGR--PGRPGQ 1097

Query: 1123 RLESVSFNQTGPYNDP--PGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGP 1173
            +  +      G    P  PG +    ++GL  +        PQGP   GP GP
Sbjct: 1098 QGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGE------PGPQGP--QGPIGP 1142



 Score = 91.7 bits (226), Expect = 5e-18
 Identities = 133/389 (34%), Positives = 160/389 (41%), Gaps = 71/389 (18%)

Query: 777  SPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLR--F 834
            +P   GP  P   R  G PG  G  G     GP G  G       +GPPGP G P R   
Sbjct: 1040 TPGEPGPQGPPGSR--GPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQ 1097

Query: 835  EGPIGQAGGGGFR-FEGSPGLR----FEGSPGGLRFEGPGGQPVGGLRFEGHRGQP--VG 887
            +G  G+ G  G R F G PG       +G PG    +GP G P+G     G +G P  VG
Sbjct: 1098 QGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQG-PIGPPGEMGPKGPPGAVG 1156

Query: 888  --GLRFE-------GPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGA-AIRFD------ 931
              GL  E       GP G P G       RG+P  GL  EG  GP G   ++ D      
Sbjct: 1157 EPGLPGEAGMKGDLGPLGTP-GEQGLIGQRGEP--GL--EGDSGPMGPDGLKGDRGDPGP 1211

Query: 932  -GPHGQPG--GGIRFEGPLLQQGV-GMRFEGPHGQS--------VAGLRFEGQHNQLG-- 977
             G HG+ G  G +  +GP    GV G+R  GP G+S              +G   QLG  
Sbjct: 1212 DGEHGEKGQEGLMGEDGPPGPPGVTGVR--GPEGKSGKQGEKGRTGAKGAKGYQGQLGEM 1269

Query: 978  GNLRFEGPHGQPGV-GIRFEGPLVQQGGGMRFEGPSVPG-----GGLRIEGPLGQGGPRF 1031
            G     GP G PG  G R  G L   G   R      PG     G   I GPLG  GP+ 
Sbjct: 1270 GVPGDPGPPGTPGPKGSR--GSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKG 1327

Query: 1032 EGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERT-------PGQPGPQRFDGPPGQQVQ 1084
            E        G+ G+    P   G  G  G R +R        PGQ G Q   G PGQQ Q
Sbjct: 1328 EKGE----QGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQ 1383

Query: 1085 PRFDGVPQRFDGPQHQQASRFDIPLGLQG 1113
            P   G P+ + GP+  + +  + P G QG
Sbjct: 1384 PGHPG-PRGWPGPKGSKGA--EGPKGKQG 1409



 Score = 87.8 bits (216), Expect = 7e-17
 Identities = 113/329 (34%), Positives = 129/329 (39%), Gaps = 44/329 (13%)

Query: 778  PRIDGPP----TPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLR 833
            P + G P       S    G PG  G  GPL   G +G +G      F GPPGP G    
Sbjct: 861  PGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIG------FPGPPGPEG---- 910

Query: 834  FEGPIGQAGGGGFR-FEGSPGLRFEGSPGGLRFEGPGGQ--PVGGLRFEGHRGQPVGGLR 890
            F G IG  G  G    +G PG R  G PG     GP G   P+G     G  GQP G   
Sbjct: 911  FPGDIGPPGDNGPEGMKGKPGAR--GLPGPRGQLGPEGDEGPMGPPGAPGLEGQP-GRKG 967

Query: 891  FEGPHG-QPVGGLRFDNPRGQPVGGLRFEGGHG----PSGAAIRFD----GPHGQPGGGI 941
            F G  G   V G   D  R  PVG   F G  G    P     + D    GP G PG   
Sbjct: 968  FPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKG 1027

Query: 942  RFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQ 1001
                P +  G+G   E P  Q   G R  G     G   R  GP G        +GP  +
Sbjct: 1028 SMGHPGMPGGMGTPGE-PGPQGPPGSR--GPPGMRGAKGR-RGPRGP-------DGPAGE 1076

Query: 1002 QGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGP 1061
            Q G    +GP  P G     G  G  G R     +  F G PG PS  P   GL G+PGP
Sbjct: 1077 Q-GSRGLKGPPGPQGRPGRPGQQGVAGERGH-LGSRGFPGIPG-PSGPPGTKGLPGEPGP 1133

Query: 1062 RFERTP-GQPGPQRFDGPPGQQVQPRFDG 1089
            +  + P G PG     GPPG   +P   G
Sbjct: 1134 QGPQGPIGPPGEMGPKGPPGAVGEPGLPG 1162



 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 112/355 (31%), Positives = 137/355 (38%), Gaps = 83/355 (23%)

Query: 777  SPRIDGPPTPASLR----------FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPG 826
            +P + GPP     +           DG+ G MG  G     GP G+ G       +G PG
Sbjct: 662  NPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKG------HKGYPG 715

Query: 827  PVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP- 885
            P G P    G  GQ G      EGSPG +  G PG     GP G P G     G+ G P 
Sbjct: 716  PAGHP----GEQGQPGP-----EGSPGAK--GYPGRQGLPGPVGDP-GPKGSRGYIGLPG 763

Query: 886  -VGGLRFEGPHGQP-VGGLRFDNPRGQPVGGLRFEGGHGPSG-----AAIRFDGPHGQPG 938
              G    +G  G P V G R     G P G     G  GP G       +   GP G PG
Sbjct: 764  LFGLPGSDGERGLPGVPGKR--GKMGMP-GFPGVFGERGPPGLDGNPGELGLPGPPGVPG 820

Query: 939  --GGIRFEGPLLQQGVGMRFEGPHGQ-----SVAGLRFEGQHNQLG-----GNLRFEGPH 986
              G +   GP+        + GP G      SV     +G   + G     G+  F+G  
Sbjct: 821  LIGDLGVLGPI-------GYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDK 873

Query: 987  GQPGV----GIRFE-GPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRF 1039
            G  G+    G R + GPL + G  G + F GP  P G     GP G  GP          
Sbjct: 874  GSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGP---------- 923

Query: 1040 DGQPGQPSLLPRFDGLHGQPGPRFERTP-GQPGPQRFDGPPGQQVQPRFDGVPQR 1093
            +G  G+P       G  G PGPR +  P G  GP    G PG + QP   G P R
Sbjct: 924  EGMKGKP-------GARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGR 971



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 118/377 (31%), Positives = 141/377 (37%), Gaps = 71/377 (18%)

Query: 750  PLFDGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGP 809
            PL     + S+   GP      GP      I  P         G PG  G        GP
Sbjct: 890  PLGKVGDKGSIGFPGPP-----GPEGFPGDIGPPGDNGPEGMKGKPGARG------LPGP 938

Query: 810  QGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGL-RFEGSPGGLRFEGP 868
            +GQLG   P   EGP GP G P    G  GQ G  G  F G PGL   +G PG     GP
Sbjct: 939  RGQLG---PEGDEGPMGPPGAP----GLEGQPGRKG--FPGRPGLDGVKGEPGDPGRPGP 989

Query: 869  GGQPVGGLRFEGHRGQP-----VGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGP 923
             G+  G + F G  G+P      G     GP G P       +P G P GG+   G  GP
Sbjct: 990  VGEQ-GFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHP-GMP-GGMGTPGEPGP 1046

Query: 924  SGAAIRFDGPHGQPG--------GGIRFEGPLLQQGVGMRFEGPHG----------QSVA 965
             G      G  G PG        G    +GP  +QG     +GP G          Q VA
Sbjct: 1047 QGP----PGSRGPPGMRGAKGRRGPRGPDGPAGEQG-SRGLKGPPGPQGRPGRPGQQGVA 1101

Query: 966  GLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLG 1025
            G   E  H    G     GP G PG        L  + G    +GP  P G +  +GP G
Sbjct: 1102 G---ERGHLGSRGFPGIPGPSGPPGT-----KGLPGEPGPQGPQGPIGPPGEMGPKGPPG 1153

Query: 1026 Q-GGPRFEGCHALRFD----GQPGQPSLL-----PRFDGLHGQPGP-RFERTPGQPGPQR 1074
              G P   G   ++ D    G PG+  L+     P  +G  G  GP   +   G PGP  
Sbjct: 1154 AVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDG 1213

Query: 1075 FDGPPGQQVQPRFDGVP 1091
              G  GQ+     DG P
Sbjct: 1214 EHGEKGQEGLMGEDGPP 1230



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 134/466 (28%), Positives = 168/466 (36%), Gaps = 116/466 (24%)

Query: 721  SDKPFVDSPASRFAGLDTNQRLTA------LAEDRPLFDGPSRPSVARD----------- 763
            S KP + S AS+ AG  ++ R          A D PL D  +RPS  +            
Sbjct: 533  SKKP-IGSEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALV 591

Query: 764  -GPTKMIFEGPNKLS--------------PRIDGPPTP-ASLRFDGSPGQMGGGGPLRFE 807
              P + +   P   S              P + GPP P       G PG  G  G     
Sbjct: 592  LAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGAR 651

Query: 808  GPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEG 867
            GP+G  G   P    G PGP G         GQ G  G     SPG   +G+ G +   G
Sbjct: 652  GPRGPPG---PYGNPGLPGPPGAK-------GQKGDPGL----SPGKAHDGAKGDMGLPG 697

Query: 868  PGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAA 927
              G P G    +GH+G P G     G  GQP        P G P G   + G  G     
Sbjct: 698  LSGNP-GPPGRKGHKGYP-GPAGHPGEQGQP-------GPEGSP-GAKGYPGRQG----- 742

Query: 928  IRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGL-RFEGQHNQLGGNLRFEGPH 986
                GP G PG     +G     G+   F  P      GL    G+  ++       G  
Sbjct: 743  --LPGPVGDPGP----KGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKM-------GMP 789

Query: 987  GQPGV-GIRFEGPLVQQGGGMRFEG-PSVPG--GGLRIEGPLGQGGPR-------FEGCH 1035
            G PGV G R    L    G +   G P VPG  G L + GP+G  GP+         G  
Sbjct: 790  GFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEP 849

Query: 1036 ALRFD-GQPGQPSL--------------LPRFDGLHGQPGPRFE-------RTPGQPGPQ 1073
             L+ D G+ G P +              LP F G  G+PGP  +         PG PGP+
Sbjct: 850  GLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPE 909

Query: 1074 RFD---GPPGQQVQPRFDGVP--QRFDGPQHQQASRFDI-PLGLQG 1113
             F    GPPG        G P  +   GP+ Q     D  P+G  G
Sbjct: 910  GFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPG 955



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 123/375 (32%), Positives = 145/375 (38%), Gaps = 84/375 (22%)

Query: 772  GPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLG-GGCPLRFEGPPGPVGT 830
            GP     R+     P    +DG  G +G  GP    GP+G+ G  G   + EGPPGP G 
Sbjct: 1291 GPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGP---PGPKGEKGEQGEDGKAEGPPGPPGD 1347

Query: 831  PLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFE-GPGGQPVGGLRFEGHRGQ----- 884
                 GP+G  G  G    G PG   +    GLR + G  GQP       GH G      
Sbjct: 1348 ----RGPVGDRGDRG--EPGDPGYPGQEGVQGLRGKPGQQGQP-------GHPGPRGWPG 1394

Query: 885  PVGGLRFEGPHGQP----------VGGLR-FDNPRGQPVGGLRFEGGHGPSGAAIRFDGP 933
            P G    EGP G+           V GL+    PRG  VG    EG  GP G   R DG 
Sbjct: 1395 PKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRG-VVGRQGLEGIAGPDGLPGR-DGQ 1452

Query: 934  HGQPG-----GGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFE-GQHNQLG---------- 977
             GQ G     G     GP  ++G       P  Q   G + E G   QLG          
Sbjct: 1453 AGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGR 1512

Query: 978  ----GNLRFEGPHGQPGVG--IRFEGPLVQQG-----GGMRFEGPSVPGG--GLR----I 1020
                GN    G  GQPG    + F G     G     G + F+G   P G  GL     I
Sbjct: 1513 TGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGI 1572

Query: 1021 EGPLGQGGPRFEGCHALRFD-GQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPP 1079
             GPLG  GP   G    + D G  G   L     G  G PGPR     G+PGP    GPP
Sbjct: 1573 VGPLGILGP--SGLPGPKGDKGSRGDWGL----QGPRGPPGPR-----GRPGP---PGPP 1618

Query: 1080 GQQVQPRFDGVPQRF 1094
            G  +Q + D +   F
Sbjct: 1619 GGPIQLQQDDLGAAF 1633



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 65/197 (32%), Positives = 76/197 (38%), Gaps = 37/197 (18%)

Query: 792  DGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE-G 850
            DG PG+ G  G    +G  G  G   P    G PG  G P   +GP G  G  G   + G
Sbjct: 1444 DGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLP-GAQGPPGFKGESGLPGQLG 1502

Query: 851  SPGLR----FEGSPGGLRFEGPGGQP--VGGLRFEGHRG-----QPVGGLRF---EGPHG 896
             PG R      G PG     G  GQP   G + F G  G      P G + F   +GP G
Sbjct: 1503 PPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRG 1562

Query: 897  QP--------VGGLRFDNPRGQP--------VGGLRFEGGHGPSGAAIRFDGPHGQPGGG 940
             P        VG L    P G P         G    +G  GP G   R  GP G PGG 
Sbjct: 1563 PPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGR-PGPPGPPGGP 1621

Query: 941  IRFEGPLLQQGVGMRFE 957
            I+    L Q  +G  F+
Sbjct: 1622 IQ----LQQDDLGAAFQ 1634


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 95.5 bits (236), Expect = 4e-19
 Identities = 140/484 (28%), Positives = 178/484 (36%), Gaps = 122/484 (25%)

Query: 755  PSRPSVARDGPTKMIFEGPNKLSPRID--------------------GPPTPASLRFDGS 794
            P  P +    PT     GP   SP+ D                    GPP P      G+
Sbjct: 135  PGPPGICESCPT-----GPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP--PGT 187

Query: 795  PGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGL 854
             G  G  G   ++GP G+ G   P    GPPG +G      GP G+ G  G    G PG 
Sbjct: 188  SGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGP----SGPAGKDGESG--RPGRPGE 241

Query: 855  RFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQP----VGGLRFDN---- 906
            R  G PG    +GP G P G    +GHRG       F+G +G+       GL+ +N    
Sbjct: 242  R--GLPGPPGIKGPAGIP-GFPGMKGHRG-------FDGRNGEKGETGAPGLKGENGLPG 291

Query: 907  ---------PRGQP----VGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQG 951
                     PRG P      GL    G   +  A   DG  G PG  G   F G    +G
Sbjct: 292  ENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKG 351

Query: 952  VGMRFEGPHGQSVAGLRFEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFE 1009
                  GP G S       GQ  + G  G+   +GP G PG+            GG    
Sbjct: 352  E----VGPAG-SPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN--------GSPGGKGEM 398

Query: 1010 GPS-VPG--GGLRIEGPLGQGGPRFEGCHALRFD-GQPGQPSLLPRFDGLHGQPGPRFER 1065
            GP+ +PG  G +   GP G  G    G   LR   G+PG+       +G  G+PGPR ER
Sbjct: 399  GPAGIPGAPGLMGARGPPGPAGA--NGAPGLRGGAGEPGK-------NGAKGEPGPRGER 449

Query: 1066 ----TPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPS 1121
                 PG PG +  DG  G   +P  +G+P        + A  F  P G  G      P 
Sbjct: 450  GEAGIPGVPGAKGEDGKDGSPGEPGANGLP---GAAGERGAPGFRGPAGPNGI-----PG 501

Query: 1122 QRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNG----PHGPGNQS 1177
            ++  +      GP   P G A      G+           P GP   G    P GPG+  
Sbjct: 502  EKGPAGERGAPGPAG-PRGAAGEPGRDGV-----------PGGPGMRGMPGSPGGPGSDG 549

Query: 1178 FSNP 1181
               P
Sbjct: 550  KPGP 553



 Score = 94.7 bits (234), Expect = 6e-19
 Identities = 143/450 (31%), Positives = 164/450 (36%), Gaps = 112/450 (24%)

Query: 754  GPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGG-GGPLRFEGPQGQ 812
            GP  PS  R  P  M F GP       DG P        G  G+ GG GGP    GPQG 
Sbjct: 564  GPPGPSGPRGQPGVMGFPGPKGN----DGAP--------GKNGERGGPGGP----GPQGP 607

Query: 813  LGGGCPLRFEGPPGPVGT--------PLRFEGPIGQAGGGGFRFE----GSPGLRFE-GS 859
             G       +GPPGP G         P   +G  G  G GG   E    G PG + + G+
Sbjct: 608  PGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGA 667

Query: 860  PGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEG 919
            PG    +G  G P       G RG P       G  G P  GLR       P GG    G
Sbjct: 668  PGAPGGKGDAGAP-------GERGPP-------GLAGAP--GLRGGAGPPGPEGGKGAAG 711

Query: 920  GHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLG 977
              GP GAA    G  G PG  GG+   GP   +G      GP    V G           
Sbjct: 712  PPGPPGAA-GTPGLQGMPGERGGLGSPGPKGDKG---EPGGPGADGVPGK---------- 757

Query: 978  GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHAL 1037
                 +GP G  G  I   GP  Q G       P +PG    I GP G  G R E     
Sbjct: 758  -----DGPRGPTG-PIGPPGPAGQPGDKGEGGAPGLPG----IAGPRGSPGERGE----- 802

Query: 1038 RFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGP 1097
               G PG P+  P   G +G+PG + ER  G PG +   GPPG    P   G P    GP
Sbjct: 803  --TGPPG-PAGFPGAPGQNGEPGGKGER--GAPGEKGEGGPPGVAGPPGGSG-PAGPPGP 856

Query: 1098 QHQQASR----------FDIPLGLQGTRFDN-HPSQRLESVSFNQTGPYNDPPGNAFNAP 1146
            Q  +  R          F    GL G    N +P     S S  + G    PPG A N  
Sbjct: 857  QGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDG----PPGPAGNT- 911

Query: 1147 SQGLQFQRHEQIFDSPQGPNFNGPHGPGNQ 1176
                          +P  P  +GP G   Q
Sbjct: 912  -------------GAPGSPGVSGPKGDAGQ 928



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 132/422 (31%), Positives = 156/422 (36%), Gaps = 73/422 (17%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P  DG P P      GS G+ G  GP    GP+GQ G    + F GP G  G P    G 
Sbjct: 545  PGSDGKPGPP-----GSQGESGRPGPPGPSGPRGQPG---VMGFPGPKGNDGAP----GK 592

Query: 838  IGQAGG-GGFRFEGSPGLRFEGSPGGLRF-EGPGGQ--PVGGLRFEGHRGQPVGGLRFEG 893
             G+ GG GG   +G PG   E  P G     GPGG     G    +G +G P  G    G
Sbjct: 593  NGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG----G 648

Query: 894  PHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--------GGIRFEG 945
            P G+  G      P+G   G     GG G +GA     G  G PG        GG    G
Sbjct: 649  PPGEN-GKPGEPGPKGD-AGAPGAPGGKGDAGA----PGERGPPGLAGAPGLRGGAGPPG 702

Query: 946  PLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGG 1005
            P   +G       P      GL  +G   + GG L   GP G  G      GP      G
Sbjct: 703  PEGGKGAAGPPGPPGAAGTPGL--QGMPGERGG-LGSPGPKGDKG---EPGGPGADGVPG 756

Query: 1006 MRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFER 1065
               +GP  P G +   GP GQ G + EG       G PG    LP   G  G PG R E 
Sbjct: 757  K--DGPRGPTGPIGPPGPAGQPGDKGEG-------GAPG----LPGIAGPRGSPGERGE- 802

Query: 1066 TPGQPGPQRFDGPPGQQVQP-----------RFDGVPQRFDGPQHQQASRFDIPLGLQGT 1114
              G PGP  F G PGQ  +P           + +G P    GP          P G QG 
Sbjct: 803  -TGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAG--PPGPQGV 859

Query: 1115 RFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGP--NFNGPHG 1172
            + +        +  F        PPG+  N    G      +   D P GP  N   P  
Sbjct: 860  KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGK---DGPPGPAGNTGAPGS 916

Query: 1173 PG 1174
            PG
Sbjct: 917  PG 918



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 109/324 (33%), Positives = 125/324 (38%), Gaps = 71/324 (21%)

Query: 782  GPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQA 841
            GPP PA     G PG  G GG     G  G  G        GPPGP G P    G  G+ 
Sbjct: 768  GPPGPA-----GQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFP-GAPGQNGEP 821

Query: 842  GGGGFRFEGSPGLRFEGSPGGLRF----EGPGGQPVGGLRFEGHRGQP--VGGLRFEGPH 895
            GG G R  G+PG + EG P G+       GP G P G    +G RG P   G   F G  
Sbjct: 822  GGKGER--GAPGEKGEGGPPGVAGPPGGSGPAGPP-GPQGVKGERGSPGGPGAAGFPGAR 878

Query: 896  GQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMR 955
            G P            P G     G  GPSG+  + DGP G P G     G     GV   
Sbjct: 879  GLP-----------GPPGSNGNPGPPGPSGSPGK-DGPPG-PAGNTGAPG---SPGVS-- 920

Query: 956  FEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG--GGMRFEGPSV 1013
              GP G +       GQ  + G      G  G PG      GPL   G  G     GP  
Sbjct: 921  --GPKGDA-------GQPGEKGS----PGAQGPPGA----PGPLGIAGITGARGLAGP-- 961

Query: 1014 PGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQ 1073
            PG    + GP G  GP+     +    G+PG   L     G  G PGP+     G PG  
Sbjct: 962  PG----MPGPRGSPGPQGVKGES----GKPGANGL----SGERGPPGPQ-----GLPGLA 1004

Query: 1074 RFDGPPGQQVQPRFDGVPQRFDGP 1097
               G PG+   P  DG+P R   P
Sbjct: 1005 GTAGEPGRDGNPGSDGLPGRDGSP 1028



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 138/468 (29%), Positives = 162/468 (34%), Gaps = 98/468 (20%)

Query: 754  GPSRPSVARDGPTKMIF-EGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQ 812
            GPS P     GP   I   GP         P  P      G PG  G  G   F G +G 
Sbjct: 210  GPSGPP----GPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGH 265

Query: 813  LG-----------GGCPLRFE----------GPPGPVGTPLR-----FEGPIGQAGGGGF 846
             G           G   L+ E          GP GP G P         G  G  G  G 
Sbjct: 266  RGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGA 325

Query: 847  R-FEGSPG-------LRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQ--PVGGLRFEGPHG 896
            R  +G PG         F GSPG     GP G P G     G RG+  P G    +GP G
Sbjct: 326  RGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSP-GSNGAPGQRGEPGPQGHAGAQGPPG 384

Query: 897  QP-----VGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQ 949
             P      GG     P G P G     G  GP G A    G +G PG  GG    G    
Sbjct: 385  PPGINGSPGGKGEMGPAGIP-GAPGLMGARGPPGPA----GANGAPGLRGGAGEPGKNGA 439

Query: 950  QGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPG-VGIRFEGPLVQQGGGMRF 1008
            +G      GP G+     R E     + G    +G  G PG  G         + G   F
Sbjct: 440  KGE----PGPRGE-----RGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGF 490

Query: 1009 EGPSVPGGGLRIEGPLGQ-GGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTP 1067
             GP+ P G    +GP G+ G P   G       G+PG+   +P   G+ G PG     +P
Sbjct: 491  RGPAGPNGIPGEKGPAGERGAPGPAGPRGAA--GEPGRDG-VPGGPGMRGMPG-----SP 542

Query: 1068 GQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTR-FDNHPSQRLES 1126
            G PG     GPPG Q +    G P    GP+ Q        +G  G +  D  P +  E 
Sbjct: 543  GGPGSDGKPGPPGSQGESGRPGPPGP-SGPRGQPG-----VMGFPGPKGNDGAPGKNGER 596

Query: 1127 VSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHGPG 1174
                  GP   P  N                    PQGP   GP GPG
Sbjct: 597  GGPGGPGPQGPPGKNGET----------------GPQGP--PGPTGPG 626



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 113/359 (31%), Positives = 126/359 (35%), Gaps = 100/359 (27%)

Query: 753  DGPSRPSVARDGPTKMIFEGPN--------KLSPRIDGPP-TPASLRFDGSPGQMGGGGP 803
            DGP  P+     P      GP         K SP   GPP  P  L   G  G  G  GP
Sbjct: 902  DGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGP 961

Query: 804  LRFEGPQGQLG-----------GGCPLRFE-GPPGPVGTPLRFEGPIGQAG-GGGFRFEG 850
                GP+G  G           G   L  E GPPGP G P    G  G+ G  G    +G
Sbjct: 962  PGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLP-GLAGTAGEPGRDGNPGSDG 1020

Query: 851  SPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQ 910
             PG   +GSPGG    G  G P G     GH G P                         
Sbjct: 1021 LPGR--DGSPGGKGDRGENGSP-GAPGAPGHPGPP------------------------G 1053

Query: 911  PVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGVGMRFEGPHGQSVAGLR 968
            PVG     G  G SG A    GP G PG  G     GP          +GP G    G  
Sbjct: 1054 PVGPAGKSGDRGESGPA----GPAGAPGPAGSRGAPGP----------QGPRGDK--GET 1097

Query: 969  FEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGG 1028
             E     + G+  F G  G PG      GP  QQ G +   GP+ P       GP+G  G
Sbjct: 1098 GERGAAGIKGHRGFPGNPGAPG----SPGPAGQQ-GAIGSPGPAGP------RGPVGPSG 1146

Query: 1029 PRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFER-------TPGQPGPQRFDGPPG 1080
            P  +       DG  G P       G  G PGPR  R       +PG PG     GPPG
Sbjct: 1147 PPGK-------DGTSGHP-------GPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPG 1191



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 134/439 (30%), Positives = 160/439 (36%), Gaps = 88/439 (20%)

Query: 782  GPPTPASLRFDGSPG---QMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGT--PLRFEG 836
            GPP P  +  +GSPG   +M   GP    G  G +G        GPPGP G        G
Sbjct: 381  GPPGPPGI--NGSPGGKGEM---GPAGIPGAPGLMGA------RGPPGPAGANGAPGLRG 429

Query: 837  PIGQAGGGGFRFEGSPGLRFE-------GSPGGLRFEGPGGQP----VGGL-RFEGHRGQ 884
              G+ G  G +  G PG R E       G PG    +G  G P      GL    G RG 
Sbjct: 430  GAGEPGKNGAK--GEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGA 487

Query: 885  PVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGG-GIRF 943
            P     F GP G P G       +G P G     G  GP GAA    G  G PGG G+R 
Sbjct: 488  P----GFRGPAG-PNG---IPGEKG-PAGERGAPGPAGPRGAAGE-PGRDGVPGGPGMR- 536

Query: 944  EGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQG 1003
                   G+     GP      G       +   G     GP GQPGV + F GP    G
Sbjct: 537  -------GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGV-MGFPGPKGNDG 588

Query: 1004 --------GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLL------ 1049
                    GG    GP  P G     GP G  GP   G       G PG   L       
Sbjct: 589  APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDK-GDTGPPGPQGLQGLPGTG 647

Query: 1050 --PRFDGLHGQPGPRFER-TPGQPGPQRFDGPPGQQVQPRFDGVP--QRFDGPQHQQASR 1104
              P  +G  G+PGP+ +   PG PG +   G PG++  P   G P  +   GP   +  +
Sbjct: 648  GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK 707

Query: 1105 FDI----PLGLQGT-RFDNHPSQRLESVSFNQTGPYNDPPG-NAFNAPSQGLQFQRHEQI 1158
                   P G  GT      P +R    S    G   +P G  A   P +          
Sbjct: 708  GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK---------- 757

Query: 1159 FDSPQGPNFN-GPHGPGNQ 1176
             D P+GP    GP GP  Q
Sbjct: 758  -DGPRGPTGPIGPPGPAGQ 775



 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 98/331 (29%), Positives = 125/331 (37%), Gaps = 71/331 (21%)

Query: 795  PGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIG-----QAGGGGF--- 846
            P   G  GP    GP G  G        G PG  G+P    GP G       G   +   
Sbjct: 99   PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSP----GPPGICESCPTGPQNYSPQ 154

Query: 847  --RFEGSPGLRFEGSPGGLRFEGPGGQ--PVGGLRFEGHRGQPVGGLRFEGPHGQPVGGL 902
               ++   G+   G  G   + GP G   P G     GH G P G   ++GP G+P G  
Sbjct: 155  YDSYDVKSGVAVGGLAG---YPGPAGPPGPPGPPGTSGHPGSP-GSPGYQGPPGEP-GQA 209

Query: 903  RFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGVGMRFEGPH 960
                P G P       G  GPSG A + DG  G+PG  G     GP    G+    +GP 
Sbjct: 210  GPSGPPGPP-------GAIGPSGPAGK-DGESGRPGRPGERGLPGP---PGI----KGPA 254

Query: 961  G-QSVAGLR----FEGQHNQLG--GNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGPSV 1013
            G     G++    F+G++ + G  G    +G +G PG      GP+  +G       P +
Sbjct: 255  GIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN-GAPGPMGPRGAPGERGRPGL 313

Query: 1014 PGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTP------ 1067
            PG      G  G  G R         DGQPG P   P   G  G PG + E  P      
Sbjct: 314  PGAA----GARGNDGARGS-------DGQPGPPG-PPGTAGFPGSPGAKGEVGPAGSPGS 361

Query: 1068 -------GQPGPQRFDGPPGQQVQPRFDGVP 1091
                   G+PGPQ   G  G    P  +G P
Sbjct: 362  NGAPGQRGEPGPQGHAGAQGPPGPPGINGSP 392



 Score = 35.8 bits (81), Expect = 0.33
 Identities = 47/172 (27%), Positives = 59/172 (34%), Gaps = 53/172 (30%)

Query: 1011 PSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQP 1070
            P+ P  G   +GP G  GP             PG P       G +G PG      PGQP
Sbjct: 95   PTRPPNGQGPQGPKGDPGP-------------PGIP-------GRNGDPG-----IPGQP 129

Query: 1071 GPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFN 1130
            G     GPPG  +       PQ +  PQ+     +D+  G+       +P          
Sbjct: 130  GSPGSPGPPG--ICESCPTGPQNY-SPQYDS---YDVKSGVAVGGLAGYP---------G 174

Query: 1131 QTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPHG-PGNQSFSNP 1181
              GP   PPG    +   G           SP  P + GP G PG    S P
Sbjct: 175  PAGP-PGPPGPPGTSGHPG-----------SPGSPGYQGPPGEPGQAGPSGP 214



 Score = 35.4 bits (80), Expect = 0.43
 Identities = 34/120 (28%), Positives = 43/120 (35%), Gaps = 3/120 (2%)

Query: 737  DTNQRLTALAEDRPLFDG-PSRPSVARDGPTKMIFEGPNKLSPRIDGPPT--PASLRFDG 793
            +T +R  A  +    F G P  P        +     P    PR    P+  P      G
Sbjct: 1096 ETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSG 1155

Query: 794  SPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPG 853
             PG +G  GP    G +G  G        GPPGP G P    G +G A   G   E + G
Sbjct: 1156 HPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGG 1215


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 114/340 (33%), Positives = 139/340 (40%), Gaps = 65/340 (19%)

Query: 792  DGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE-G 850
            +G PG+ G  GP   +GPQG  G   P    G PG  G P    GP G  G  G + E G
Sbjct: 749  EGLPGKDGDTGPTGPQGPQGPRG---PPGKNGSPGSPGEP----GPSGTPGQKGSKGENG 801

Query: 851  SPGLRFEGSPGGLRFEGPGGQP--VGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNP- 907
            SPGL     PG L   GP G+P   G    EG  G+P G   F+G  G P  G++ D   
Sbjct: 802  SPGL-----PGFLGPRGPPGEPGEKGVPGKEGVPGKP-GEPGFKGERGDP--GIKGDKGP 853

Query: 908  ---RGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGV-GMRFEGPHG 961
               +GQP G     G  G +G      GP G PG  G +   GP  Q G  G+R E P  
Sbjct: 854  PGGKGQP-GDPGIPGHKGHTGLM----GPQGLPGENGPVGPPGPPGQPGFPGLRGESPSM 908

Query: 962  QSVAGLRFEGQHNQLGGNLRF----------------EGPHGQPGVGIRFEGPLVQQGGG 1005
            +++  L  E    QL   L +                 GP G PG     +  L  + G 
Sbjct: 909  ETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPG-----KDGLPGRAGP 963

Query: 1006 MRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSL-------LPRFDGLHGQ 1058
            M   G    GG   +EGP G  GP+ E        G PG P +        P   G  G+
Sbjct: 964  MGEPGRPGQGG---LEGPSGPIGPKGER----GAKGDPGAPGVGLRGEMGPPGIPGQPGE 1016

Query: 1059 PGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQ 1098
            PG   +  PG PGPQ   GP G    P   G P + D  Q
Sbjct: 1017 PGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQ 1056



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 113/336 (33%), Positives = 138/336 (41%), Gaps = 63/336 (18%)

Query: 793  GSPGQMGGGGPLRF---EGPQGQLGGGCPLRFEGPPGPVGTPLR--------FEGPIGQA 841
            G+PG  G  G +     EG  G+ G   P   +GP GP G P +          GP G  
Sbjct: 732  GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTP 791

Query: 842  GGGGFRFE-GSPGLRFEGSPGGLRFEGPGGQP--VGGLRFEGHRGQPVGGLRFEGPHGQP 898
            G  G + E GSPGL     PG L   GP G+P   G    EG  G+P G   F+G  G P
Sbjct: 792  GQKGSKGENGSPGL-----PGFLGPRGPPGEPGEKGVPGKEGVPGKP-GEPGFKGERGDP 845

Query: 899  VGGLRFD----NPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGV 952
              G++ D      +GQP G     G  G +G      GP G PG  G +   GP  Q G 
Sbjct: 846  --GIKGDKGPPGGKGQP-GDPGIPGHKGHTGLM----GPQGLPGENGPVGPPGPPGQPGF 898

Query: 953  -GMRFEGPHGQSVAGLRFEGQHNQLGGNLRF-------------------EGPHGQPGVG 992
             G+R E P  +++  L  E    QL   L +                    GP G+ G+ 
Sbjct: 899  PGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLP 958

Query: 993  IRFEGPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALR----FDGQPGQP 1046
             R  GP+ + G  G    EGPS P G     G  G  G    G           GQPG+P
Sbjct: 959  GR-AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEP 1017

Query: 1047 SLLPRFDGLHGQPGPRFERTP-GQPGPQRFDGPPGQ 1081
                  DGL G PGP+ E  P G PG     GPPGQ
Sbjct: 1018 GYAK--DGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1051



 Score = 84.7 bits (208), Expect = 6e-16
 Identities = 125/426 (29%), Positives = 161/426 (37%), Gaps = 74/426 (17%)

Query: 783  PPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGG----------GCPLRF-----EGPPGP 827
            P  P      G PG++G  GP    G +GQ G           G P         GPPG 
Sbjct: 358  PGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGS 417

Query: 828  VGTP-LRF----EGPIGQAGGGGFRFEGSPG-LRFEGSPGGLRFEGPGGQPVGGLRFEGH 881
            VG P LR     +G  G+ G  G   EGSPG +   G PG     GP G+   G    G 
Sbjct: 418  VGAPGLRGTPGKDGERGEKGAAGE--EGSPGPVGPRGDPGAPGLPGPPGKGKDGE--PGL 473

Query: 882  RGQP--VGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG- 938
            RG P   G L  +G  G P G       RG P  G+   G  GPSG      G  G PG 
Sbjct: 474  RGSPGLPGPLGTKGDRGAP-GIPGSPGSRGDP--GIGVAGPPGPSGPP----GDKGSPGS 526

Query: 939  -GGIRFEGPLLQQGVGMRFEGPHGQS-VAGLRFEGQHNQLGGNLRFEGPHGQPGV----G 992
             G   F GP          +GP G+  ++ L   G  N L  ++  + P G PG+    G
Sbjct: 527  RGLPGFPGP----------QGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPG 576

Query: 993  IRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRF 1052
             + +  +  + G    EG     G   + GP G  GP+          G  G+       
Sbjct: 577  FKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ----------GSQGERGA---- 622

Query: 1053 DGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQ 1112
            DG  GQ G +     G PG   F GPPG    P  DG+      P  Q +   + P G Q
Sbjct: 623  DGEVGQKGDQ-----GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQ 677

Query: 1113 G-TRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGPH 1171
            G +     P +  +     + GP  + PG A      G +  R    F    G   +G  
Sbjct: 678  GPSGLPGIPGEEGKEGRDGKPGPPGE-PGKAGEPGLPGPEGARGPPGFKGHTGD--SGAP 734

Query: 1172 GPGNQS 1177
            GP  +S
Sbjct: 735  GPRGES 740



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 131/434 (30%), Positives = 159/434 (36%), Gaps = 84/434 (19%)

Query: 750  PLFDGPSRPSVARDGPTKMIFEGP-NKLSPRI--DGPPTPASLR-FDGSPGQMGGGGPLR 805
            P F GP  P+  RDG + ++  G  N L+  +  D PP P  L    G  G  G  G   
Sbjct: 530  PGFPGPQGPA-GRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG 588

Query: 806  FEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRF 865
             EG +G+ G   P    GPPG  G     +G  G+ G  G    G  G   +G PG   F
Sbjct: 589  REGTEGKKGEAGPPGLPGPPGIAGP----QGSQGERGADGE--VGQKG--DQGHPGVPGF 640

Query: 866  EGPGGQP--VGGLRFEGHRGQP--VGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGH 921
             GP G P   G     G  G P   G    EGP G P G      P G P G    EG  
Sbjct: 641  MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG-PQG------PSGLP-GIPGEEGKE 692

Query: 922  GPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLR 981
            G  G      GP G+PG   +   P L    G R  GP G       F+G     G    
Sbjct: 693  GRDGKP----GPPGEPG---KAGEPGLPGPEGAR--GPPG-------FKGHTGDSGA--- 733

Query: 982  FEGPHGQPG-VGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFD 1040
              GP G+ G +G+  +  L  + G     GP+ P G     GP G+ G            
Sbjct: 734  -PGPRGESGAMGLPGQEGLPGKDGDT---GPTGPQGPQGPRGPPGKNGS----------P 779

Query: 1041 GQPGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQ 1100
            G PG+P       G  GQ G + E   G PG   F GP G   +P   GVP +   P   
Sbjct: 780  GSPGEPGP----SGTPGQKGSKGEN--GSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 833

Query: 1101 QASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFD 1160
                F    G  G + D                    PPG        G+   +      
Sbjct: 834  GEPGFKGERGDPGIKGD------------------KGPPGGKGQPGDPGIPGHKGHTGLM 875

Query: 1161 SPQG-PNFNGPHGP 1173
             PQG P  NGP GP
Sbjct: 876  GPQGLPGENGPVGP 889



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 96/327 (29%), Positives = 113/327 (34%), Gaps = 89/327 (27%)

Query: 783  PPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRF-------- 834
            P  P      G  G  G  G L   G +G  G        GPPG  GT   F        
Sbjct: 288  PGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPG 347

Query: 835  -EGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEG 893
             +GP G+ G  G    G PGL  +G PG L  +GP G P       G +GQ       EG
Sbjct: 348  EQGPKGEKGDPGL--PGEPGL--QGRPGELGPQGPTGPP-------GAKGQ-------EG 389

Query: 894  PHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSG--AAIRFDGPHGQPGGGIRFEGPLLQQG 951
             HG P          G P G     G  GPSG   ++   G  G PG             
Sbjct: 390  AHGAP-------GAAGNP-GAPGHVGAPGPSGPPGSVGAPGLRGTPGK------------ 429

Query: 952  VGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMRFEGP 1011
                 +G  G+  A     G+    G      GP G PG       P +    G   +G 
Sbjct: 430  -----DGERGEKGAA----GEEGSPGP----VGPRGDPGA------PGLPGPPGKGKDGE 470

Query: 1012 SVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRFERTPGQPG 1071
                G   + GPLG  G R          G PG P          G PG R +   G  G
Sbjct: 471  PGLRGSPGLPGPLGTKGDR----------GAPGIP----------GSPGSRGDPGIGVAG 510

Query: 1072 PQRFDGPPGQQVQPRFDGVPQRFDGPQ 1098
            P    GPPG +  P   G+P  F GPQ
Sbjct: 511  PPGPSGPPGDKGSPGSRGLP-GFPGPQ 536


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 94.4 bits (233), Expect = 8e-19
 Identities = 138/461 (29%), Positives = 170/461 (36%), Gaps = 88/461 (19%)

Query: 752  FDGPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQG 811
            F GP  P   + GP      GP    P +  P  P      G PG  G  GP   +G +G
Sbjct: 614  FPGPLGPP-GKAGPV-----GP----PGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKG 663

Query: 812  QL--------GGGCPLRFEGPPGPVGTPLRFEGPIGQAG-GGGFRFEGSPGLRFEGSPGG 862
                      G   P  F+GPPGP G    F GP G  G  G    +G P     G+PG 
Sbjct: 664  DTISCNVTYPGRHGPPGFDGPPGPKG----FPGPQGAPGLSGSDGHKGRP-----GTPGT 714

Query: 863  LRFEGPGG--QPVGGLRFEGHRG-QPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEG 919
                GP G    +G   F G +G  PVG     GP G P    +   P     G L   G
Sbjct: 715  AEIPGPPGFRGDMGDPGFGGEKGSSPVGP---PGPPGSPGVNGQKGIPGDPAFGHLGPPG 771

Query: 920  GHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGN 979
              G SG      GP G PG     EGP    G  +  +GP G+               G+
Sbjct: 772  KRGLSGVP-GIKGPRGDPGCP-GAEGPAGIPGF-LGLKGPKGRE--------------GH 814

Query: 980  LRFEGPHGQPGVGIRFEGP-LVQQGGGMRFEG-PSVPG-----GGLRIEGPLGQGG---- 1028
              F G  G PG       P +  Q G   + G P  PG     G +   GP G  G    
Sbjct: 815  AGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGL 874

Query: 1029 PRFEGCHALRFDGQPGQPSLLPRF--DGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPR 1086
            P   G H     G PG P +   F  DGL G PGP+  R  G PG   F G PG++ +P 
Sbjct: 875  PGRPGAH-----GPPGLPGIPGPFGDDGLPGPPGPKGPR--GLPG---FPGFPGERGKPG 924

Query: 1087 FDGVPQRFDGPQHQQASRFDIPLGLQGTR-FDNHPSQRLESVSFNQTGPYNDP------- 1138
             +G P     P  +  S      GL+G +     P    E    +Q G   +P       
Sbjct: 925  AEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDG 984

Query: 1139 -PGNAFNAPSQGLQFQRHEQIFDSPQG-----PNFNGPHGP 1173
             PG   +  + G+Q +R E     P G     P   G  GP
Sbjct: 985  FPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGP 1025



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 136/438 (31%), Positives = 157/438 (35%), Gaps = 93/438 (21%)

Query: 772  GPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP 831
            G   L   I  P  P      GSPG  G  G     GP+G  G   P    GPPGP G P
Sbjct: 1033 GSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGD--PASHFGPPGPKGEP 1090

Query: 832  LRFEGPIGQAGGGGFRFEGSPGLR----FEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVG 887
                G  G  G  G   +G PG++      G PG     GP G P G     G RGQP G
Sbjct: 1091 -GSPGCPGHFGASG--EQGLPGIQGPRGSPGRPGPPGSSGPPGCP-GDHGMPGLRGQP-G 1145

Query: 888  GLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEG 945
             +   GP G           +G P       G  GP G      GP G PG  G    +G
Sbjct: 1146 EMGDPGPRGL----------QGDP-------GIPGPPG----IKGPSGSPGLNGLHGLKG 1184

Query: 946  PLLQQGV-GMRFEGPHGQ-SVAGLRFE-GQHNQLG----GNLRFEGPHGQPGVGIRFEGP 998
                +G  G+   GP G   + GL+ E G     G    G    +GP G PG      GP
Sbjct: 1185 QKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPG----SSGP 1240

Query: 999  LVQQGGGMR----FEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDG 1054
                G   R       P  PG     +GP G  GPR          G PG P L    D 
Sbjct: 1241 PGPAGATGRAPKDIPDPGPPGD----QGPPGPDGPR----------GAPGPPGLPGSVDL 1286

Query: 1055 LHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGV-----PQRFDGPQHQQASRFDIPL 1109
            L G+PG      PG PGP    GPPG +  P  DG      P  F GPQ      F  P 
Sbjct: 1287 LRGEPGDC--GLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHG--FPGPP 1342

Query: 1110 GLQGTRFDNHPSQRLESVSFNQTGPYND--PPGNAFNAPSQGLQFQRHEQIFDSPQGPNF 1167
            G +G      P            GP  +  PP +  + P          +I   P  P  
Sbjct: 1343 GEKGL-----PGPPGRKGPTGLPGPRGEPGPPADVDDCP----------RIPGLPGAPGM 1387

Query: 1168 NGPHG----PGNQSFSNP 1181
             GP G    PG +  S P
Sbjct: 1388 RGPEGAMGLPGMRGPSGP 1405



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 109/354 (30%), Positives = 135/354 (38%), Gaps = 56/354 (15%)

Query: 771  EGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGT 830
            +GP   SP   GPP  +     G PG  G  G     G  G++G   P   +G PG  G 
Sbjct: 1111 QGPRG-SPGRPGPPGSS-----GPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGP 1164

Query: 831  PLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVG-GL 889
            P   +GP G  G  G    G  G +      GL   GP G PVG    +G RG P   G+
Sbjct: 1165 P-GIKGPSGSPGLNG--LHGLKGQKGTKGASGLHDVGPPG-PVGIPGLKGERGDPGSPGI 1220

Query: 890  RFEGPHGQ--PVGGLRFDNPRGQPVGGLRF----------EGGHGPSGAAIRFDGPHGQP 937
               GP G+  P G      P G P G               G  GP G     DGP G P
Sbjct: 1221 SPPGPRGKKGPPGPPGSSGPPG-PAGATGRAPKDIPDPGPPGDQGPPGP----DGPRGAP 1275

Query: 938  G-GGIRFEGPLLQQGVG-MRFEGPHG----QSVAGLR-FEGQHNQLG--GNLRFEGPHGQ 988
            G  G+     LL+   G     GP G        G + F G   + G  G + F GP G 
Sbjct: 1276 GPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGP 1335

Query: 989  PGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSL 1048
             G    F GP  ++G      GP    G   + GP G+ GP  +     R  G PG P +
Sbjct: 1336 HG----FPGPPGEKG----LPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGM 1387

Query: 1049 -----LPRFDGLHGQPGPRFERTPGQPGPQRFD------GPPGQQVQPRFDGVP 1091
                      G+ G  GP  +  PG  G +  D      GPPG++     DG P
Sbjct: 1388 RGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYP 1441



 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 133/434 (30%), Positives = 161/434 (37%), Gaps = 87/434 (20%)

Query: 782  GPPTPASLRFDGSPGQ-----MGGGGPLRFEGPQGQLG-GGCPLRFEGPPGPVGTPLRFE 835
            GPP P  L   G PG+     +G  GP  F G  G  G  G P R +  PG  G P    
Sbjct: 385  GPPGPPGLL--GRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKP---- 438

Query: 836  GPIGQAGGGGFRFEGSPGLRF----EGSPGGLRFEGPGGQPVGGLRFEGHRGQP------ 885
            G  G  G  G   +G PG        G+PG    +G  G P GG   +G +G        
Sbjct: 439  GSPGLPGAPGL--QGLPGSSVIYCSVGNPGPQGIKGKVGPP-GGRGPKGEKGNEGLCACE 495

Query: 886  VGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG------- 938
             G +   GP G P G        G P G L  +G  GP GA    +GP G PG       
Sbjct: 496  PGPMGPPGPPGLP-GRQGSKGDLGLP-GWLGTKGDPGPPGA----EGPPGLPGKHGASGP 549

Query: 939  -GGIRFEGPLLQQGV-GMRFE-GPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRF 995
             G    +G ++   V G + E GP G       F GQ    G +    G  G PG     
Sbjct: 550  PGNKGAKGDMVVSRVKGHKGERGPDGPP----GFPGQPGSHGRD-GHAGEKGDPGPPGDH 604

Query: 996  EGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQG--GPRFEGCHALRFDGQPGQPSLLPRFD 1053
            E       GG  F GP  P G     GP G G  GP  E  H     G PG P +    D
Sbjct: 605  EDATP---GGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHP----GVPGHPGVRGP-D 656

Query: 1054 GLHGQPGPRFERT---PGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLG 1110
            GL GQ G         PG+ GP  FDGPPG          P+ F GPQ           G
Sbjct: 657  GLKGQKGDTISCNVTYPGRHGPPGFDGPPG----------PKGFPGPQGAP--------G 698

Query: 1111 LQGTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGPNFNGP 1170
            L G+  D H  +         T     PPG   +    G   ++       P  P   G 
Sbjct: 699  LSGS--DGHKGR----PGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGV 752

Query: 1171 HG----PGNQSFSN 1180
            +G    PG+ +F +
Sbjct: 753  NGQKGIPGDPAFGH 766



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 125/433 (28%), Positives = 151/433 (34%), Gaps = 89/433 (20%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGP 837
            P   GPP P      G  G  G  G   F G +G LG G PL   G  G  G  +   G 
Sbjct: 124  PGHPGPPGPRGK--PGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGA 181

Query: 838  IGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQ 897
            +    G      G PGL   G PG     GP G         G+ G+P  GL   GP GQ
Sbjct: 182  VKGIQGD----RGDPGL--PGLPGSWGAGGPAGPT-------GYPGEP--GL--VGPPGQ 224

Query: 898  PVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGP---LLQQGVGM 954
            P       NP      G+  +G  G  G      G  G PG  +  E P   L +   G+
Sbjct: 225  PGRPGLKGNP------GVGVKGQMGDPGEV----GQQGSPGPTLLVEPPDFCLYKGEKGI 274

Query: 955  R-------FEGPHGQS-VAGLRFEGQHNQLGGNLRFEGPHGQPGV-------GIRFEGPL 999
            +         GP G+   +G+  +G+    G    F GP G PG        G++ E  L
Sbjct: 275  KGIPGMVGLPGPPGRKGESGIGAKGEKGIPG----FPGPRGDPGSYGSPGFPGLKGELGL 330

Query: 1000 VQQGGGMRFEGPSVPGGGLRIEGPLG------------QGGPRFEGCHALRFD-GQPGQP 1046
            V   G     GP    G     GP G             G P F G +    D G PG P
Sbjct: 331  VGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPP 390

Query: 1047 SLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDG-PQHQQASRF 1105
             LL       G+PG       G PGPQ F G PG   +    G P    G P    +   
Sbjct: 391  GLL-------GRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGL 443

Query: 1106 DIPLGLQGTRFDNHPSQRLESVSFNQTGPYN-----DPPGNAFNAPSQGLQFQRHEQIFD 1160
                GLQG      P   +   S    GP        PPG       +G     +E +  
Sbjct: 444  PGAPGLQGL-----PGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKG-----NEGLCA 493

Query: 1161 SPQGPNFNGPHGP 1173
               GP   GP GP
Sbjct: 494  CEPGP--MGPPGP 504



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 146/517 (28%), Positives = 187/517 (36%), Gaps = 84/517 (16%)

Query: 778  PRIDGPP-TPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEG 836
            P  +GP   P  L   G  G+ G  G   F G  G  G  C     G PG  G P  + G
Sbjct: 791  PGAEGPAGIPGFLGLKGPKGREGHAG---FPGVPGPPGHSCERGAPGIPGQPGLP-GYPG 846

Query: 837  PIGQAGGGGFRFE-GSPG----LRFEGSPGGLRFEGPGGQP-----------VGGLRFEG 880
              G  GG G   + G PG        G PG     GP G P            G    +G
Sbjct: 847  SPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKG 906

Query: 881  HRGQPVGGLRFEGPHGQPVGGLRFDNPRGQP----VGGLRFEGG-HGPSGAAIRFDGPHG 935
             RG P G   F G  G+P G       +G+P    + GL  + G  G  GA     GP G
Sbjct: 907  PRGLP-GFPGFPGERGKP-GAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAI----GPPG 960

Query: 936  QPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRF 995
              G     E  ++ Q       GP G       F G+     G    +G  G+PG   R+
Sbjct: 961  DEG-----EMAIISQKGTPGEPGPPGDD----GFPGERGD-KGTPGMQGRRGEPG---RY 1007

Query: 996  EGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPR-FEGCHALRFD-GQPGQPSLLPRFD 1053
              P   +G       P  PG      GP G  G R F G   L  D G+PG P   P F 
Sbjct: 1008 GPPGFHRGEPGEKGQPGPPGP----PGPPGSTGLRGFIGFPGLPGDQGEPGSPG-PPGFS 1062

Query: 1054 GLHGQPGPRFERTPGQPG-PQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQ 1112
            G+ G  GP+     G  G P    GPPG + +P   G P  F     Q      +P G+Q
Sbjct: 1063 GIDGARGPK-----GNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQ-----GLP-GIQ 1111

Query: 1113 GTRFDNHPSQRLESVSFNQTGP--YNDPPGNAFNAPSQGLQFQRHEQIFDSPQG----PN 1166
            G R            S  + GP   + PPG   +    GL+ Q  E     P+G    P 
Sbjct: 1112 GPR-----------GSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPG 1160

Query: 1167 FNGPHGPGNQSFSNPLNRASGHYFDEKNLQSSQFGNFGNIPAPMTVGNIQASQ--QVLSG 1224
              GP G    S S  LN   G    +    +S   + G  P P+ +  ++  +      G
Sbjct: 1161 IPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGP-PGPVGIPGLKGERGDPGSPG 1219

Query: 1225 VAQPVAFGQGQQFLPVHPQNPGFVQNPSGALPKAYPD 1261
            ++ P   G+     P     P      +G  PK  PD
Sbjct: 1220 ISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPD 1256



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 66/202 (32%), Positives = 79/202 (39%), Gaps = 46/202 (22%)

Query: 755  PSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLR-FDGSPGQMGGGGPLRFEGPQGQL 813
            P    + R  P      GP    P   GPP P   + F G  G+ G  GP+ F GPQG  
Sbjct: 1281 PGSVDLLRGEPGDCGLPGP----PGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQG-- 1334

Query: 814  GGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRF-EGSPG--------LRFEGSPGGLR 864
                P  F GPPG  G P    GP G+ G  G     G PG         R  G PG   
Sbjct: 1335 ----PHGFPGPPGEKGLP----GPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPG 1386

Query: 865  FEGP-GGQPVGGLR---FEGHRGQP-VGGLR-FEGPHGQPVGGLRFDNPRGQ--PVGGLR 916
              GP G   + G+R     G +G+P + G R  +G  G P        P G+    G   
Sbjct: 1387 MRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSP-------GPPGRKGDTGEDG 1439

Query: 917  FEGGHGPSGAAIRFDGPHGQPG 938
            + GG GP        GP G PG
Sbjct: 1440 YPGGPGP-------PGPIGDPG 1454



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 24/57 (42%), Positives = 25/57 (43%), Gaps = 12/57 (21%)

Query: 792  DGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGG--GGF 846
            DG PG  G  G     G  G  GG       GPPGP+G P    GP G   G  GGF
Sbjct: 1420 DGVPGSPGPPGRKGDTGEDGYPGG------PGPPGPIGDP----GPKGFGPGYLGGF 1466


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 159/534 (29%), Positives = 199/534 (37%), Gaps = 105/534 (19%)

Query: 777  SPRIDGPPTPASLR------FDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGT 830
            SP   GP  P   +       DG+PG  G  G    +GP+G  G   P    G PGP+G 
Sbjct: 1431 SPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGE 1490

Query: 831  PLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP----V 886
                +G  G  G  G R  G PG+   G PG    EGP G P G    +G  G+P    V
Sbjct: 1491 AGE-KGERGPPGPAGSR--GLPGV--AGRPGAKGPEGPPG-PTGRQGEKGEPGRPGDPAV 1544

Query: 887  GGLRFEGPHGQ--------PVGGLRFDNPRGQPVGGLRFEGGHGPSG-----AAIRFDGP 933
             G    GP G+        P G       RG P  GL   G  GP G       I   G 
Sbjct: 1545 VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPP--GLVLPGDPGPKGDPGDRGPIGLTGR 1602

Query: 934  HGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGV-- 991
             G PG      GP  ++G   R  GP G  V     +G+  + G     EGP G PG+  
Sbjct: 1603 AGPPGD----SGPPGEKGDPGR-PGPPG-PVGPRGRDGEVGEKGD----EGPPGDPGLPG 1652

Query: 992  -----GIR----FEGPLVQQG--------GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGC 1034
                 G+R      GP+ ++G        G     G S P G     GP G  G   +  
Sbjct: 1653 KAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTG 1712

Query: 1035 HALRFDGQPGQPSLLPRFDGLHGQPGPRFER-------TPGQPGPQRFDGPPGQQVQPRF 1087
               R  G+PG            GQ GPR  +        PG+ G + F GPPG Q  P  
Sbjct: 1713 PGAREKGEPGD----------RGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDP-- 1760

Query: 1088 DGVPQRFDGPQHQQASRFDIPLGLQG-TRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAP 1146
             GV     GP  ++  R   P GL G +  D  P       +   +GP N   G A +  
Sbjct: 1761 -GV----RGPAGEKGDRG--PPGLDGRSGLDGKPG------AAGPSGP-NGAAGKAGDPG 1806

Query: 1147 SQGLQFQRHEQIFDSPQGPNFNGPHGPGNQSFSNPLNRASGHYFDEKNLQSSQFGNFGNI 1206
              GL   R EQ    P GP   G  G   +     LN  +G   D    +  + G  G+ 
Sbjct: 1807 RDGLPGLRGEQGLPGPSGP--PGLPGKPGEDGKPGLNGKNGEPGDPG--EDGRKGEKGDS 1862

Query: 1207 PAPMTVG-NIQASQQVLSGVAQPVAFGQGQQFL--PVHPQNPGFVQNPSGALPK 1257
             A    G +    ++   G+  P    QG   L  PV P   GF   P G  PK
Sbjct: 1863 GASGREGRDGPKGERGAPGILGP----QGPPGLPGPVGPPGQGFPGVPGGTGPK 1912



 Score = 87.8 bits (216), Expect = 7e-17
 Identities = 123/382 (32%), Positives = 149/382 (39%), Gaps = 67/382 (17%)

Query: 793  GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSP 852
            G PG+ G  GP    G QG  G   P+   G PGP G P    GP G  G  G +  G P
Sbjct: 2153 GLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAP-GLAGPAGPQGPSGLK--GEP 2209

Query: 853  GLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPV 912
            G   E  P G    G    P G +   G    P G     GP G P  GL      GQ V
Sbjct: 2210 G---ETGPPGRGLTG----PTGAVGLPG----PPGPSGLVGPQGSP--GL-----PGQ-V 2250

Query: 913  GGLRFEGGHGPSGAAIRFDGPHGQPG--GGIRFEGPLLQQGVGMRFEGPHGQSVAGL--- 967
            G     G  G  GA+ + DG  G PG  G     GP+  +G       P GQ+V GL   
Sbjct: 2251 GETGKPGAPGRDGASGK-DGDRGSPGVPGSPGLPGPVGPKGEPGPTGAP-GQAVVGLPGA 2308

Query: 968  -RFEGQHNQLGGNLRFE-GPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLG 1025
               +G    L G+L  E G  G  G+     GP  ++G   R   P  PG     +G  G
Sbjct: 2309 KGEKGAPGGLAGDLVGEPGAKGDRGL----PGPRGEKGEAGRAGEPGDPGE----DGQKG 2360

Query: 1026 QGGPR-FEGCHALRFDGQPGQPSL--------------LPRFDGLHGQPGPRFERTPGQP 1070
              GP+ F+G   +   G PG P                 P   G  GQ GPR E   GQP
Sbjct: 2361 APGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEM--GQP 2418

Query: 1071 GP---QRFDGPPGQQVQPRFDGVP-----QRFDGPQHQQASRFDIPLGLQGTRFD-NHPS 1121
            GP   +   GPPG++  P   G P         G    +  + D  +GL G R +   P 
Sbjct: 2419 GPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPG 2478

Query: 1122 QRLESVSFNQTGP--YNDPPGN 1141
             R E     Q GP     PPG+
Sbjct: 2479 IRGEDGRPGQEGPRGLTGPPGS 2500



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 126/432 (29%), Positives = 161/432 (37%), Gaps = 82/432 (18%)

Query: 778  PRIDGPPTPASLRFD-------------GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGP 824
            P   GPP P  ++ D             G PGQ G  G +   GP G+ G   P   EG 
Sbjct: 2376 PGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI 2435

Query: 825  PGPVGTPLRFEGPIGQAGGGGFRFE-GSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRG 883
            PGP+G P    G +G  G  G + + G PG+   G PG     G  G+P  G+R E  R 
Sbjct: 2436 PGPLGPP-GPPGSVGPPGASGLKGDKGDPGV---GLPGP---RGERGEP--GIRGEDGRP 2486

Query: 884  QPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRF 943
               G     GP G      R +      VG    +G  G S   +   GP G   G +  
Sbjct: 2487 GQEGPRGLTGPPGS-----RGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAK-GDMGE 2540

Query: 944  EGPL-LQQGVGMRFEG--PHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGV--------- 991
             GP  L    G R +   P  +   G   +     L G     GP GQPG          
Sbjct: 2541 RGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGS 2600

Query: 992  -------GIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPG 1044
                   GIR E       G + F GP    G   ++G  G  G + +   A    G PG
Sbjct: 2601 PGKDGVPGIRGE------KGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEA----GPPG 2650

Query: 1045 QPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASR 1104
            +P L     G  G+PG      PGQ G    +G  G +    FDG P    GP+  Q  +
Sbjct: 2651 RPGLAGH-KGEMGEPG-----VPGQSGAPGKEGLIGPKGDRGFDGQP----GPKGDQGEK 2700

Query: 1105 FDIPLGLQGT-RFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQ 1163
                 G +GT      P     S +    GP   PPG+      +GLQ Q+ E+    P 
Sbjct: 2701 -----GERGTPGIGGFPG---PSGNDGSAGP-PGPPGSVGPRGPEGLQGQKGER---GPP 2748

Query: 1164 GPNFNGPHG-PG 1174
            G    G  G PG
Sbjct: 2749 GERVVGAPGVPG 2760



 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 119/346 (34%), Positives = 139/346 (40%), Gaps = 50/346 (14%)

Query: 755  PSRPSVARDGPTKMIFEGPNKLS--PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQ 812
            P  P +A  GP     +GP+ L   P   GPP        G+ G  G  GP    GPQG 
Sbjct: 2188 PGAPGLA--GPAGP--QGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGS 2243

Query: 813  LGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQP 872
             G        G  G  G P    G  G +G  G R  GSPG+   GSPG     GP G+P
Sbjct: 2244 PG------LPGQVGETGKP-GAPGRDGASGKDGDR--GSPGV--PGSPGLPGPVGPKGEP 2292

Query: 873  VGGLRFEGHRGQPVGGL-RFEGPHGQPVGGLRFDNPRGQP--VGGLRFEGGHGPSGAAIR 929
                   G  GQ V GL   +G  G P GGL  D   G+P   G     G  G  G A R
Sbjct: 2293 GP----TGAPGQAVVGLPGAKGEKGAP-GGLAGDLV-GEPGAKGDRGLPGPRGEKGEAGR 2346

Query: 930  FDGPHGQPG--GGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHG 987
               P G PG  G     GP         F+G  G  V G         + G+L   G  G
Sbjct: 2347 AGEP-GDPGEDGQKGAPGP-------KGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPG 2398

Query: 988  QPGVGIRFEGPLVQQG-----GGMRFEGPSVPGGGLRIEGPLGQGGPRFE----GCHALR 1038
             PGV + F G    +G     G     G + P G   I GPLG  GP       G   L+
Sbjct: 2399 APGV-VGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLK 2457

Query: 1039 FDGQPGQPSL-LPRFDGLHGQPGPRFE-RTPGQPGPQRFDGPPGQQ 1082
              G  G P + LP   G  G+PG R E   PGQ GP+   GPPG +
Sbjct: 2458 --GDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSR 2501



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 115/351 (32%), Positives = 137/351 (39%), Gaps = 64/351 (18%)

Query: 778  PRIDGPP-TPASLRFDGSPGQMGGGGPLRFEGPQGQL----------------------G 814
            P  DG P +P      G+PG  G  G     GP+G                        G
Sbjct: 1301 PGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEG 1360

Query: 815  GGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRF-EGSPGLRFEGSPGGLRFEGPGGQPV 873
             G P R +G PGP G P    GP G  G  G R   G PG   +G  G     GP G   
Sbjct: 1361 PGLPGR-KGDPGPSGPP----GPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGE 1415

Query: 874  GGLRFEGHRGQP--VGGLRFEGPHGQP-VGGLRFDNPRGQP-----VGGLRFEGGHGPSG 925
            GG+   G  G P   G    +GP G P   G + D+  G P      G    +G  GP G
Sbjct: 1416 GGIA-PGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPG 1474

Query: 926  AAIRFDGPHGQPGGGIRFEGPLLQQG-VGMRFEGPHGQSVAGLR-FEGQHNQLGGNLRFE 983
            A     GP G  G    F GPL + G  G R  GP G   AG R   G    + G    +
Sbjct: 1475 AI----GPKGDRG----FPGPLGEAGEKGER--GPPGP--AGSRGLPG----VAGRPGAK 1518

Query: 984  GPHGQPG-VGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQ 1042
            GP G PG  G + E     + G     GP+V  G    +G +G  GPR     A    G+
Sbjct: 1519 GPEGPPGPTGRQGEKGEPGRPGDPAVVGPAV-AGPKGEKGDVGPAGPR----GATGVQGE 1573

Query: 1043 PGQPSL-LPRFDGLHGQPGPRFE-RTPGQPGPQRFDGPPGQQVQPRFDGVP 1091
             G P L LP   G  G PG R      G+ GP    GPPG++  P   G P
Sbjct: 1574 RGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPP 1624



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 105/325 (32%), Positives = 128/325 (39%), Gaps = 52/325 (16%)

Query: 782  GPPTPASLRFD-GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQ 840
            G P    LR   G PG  G  G     GPQG  G        G PG  G P    G  G+
Sbjct: 1257 GEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRP----GSPGR 1312

Query: 841  AGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVG 900
            AG  G    G+PGL+  GSPG     GP G P G     G +G+P    +  G  G  + 
Sbjct: 1313 AGNPG--TPGAPGLK--GSPG---LPGPRGDP-GERGPRGPKGEPGAPGQVIGGEGPGLP 1364

Query: 901  GLRFD-NPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFE-G 958
            G + D  P G P       G  GP G      GP G PG      G  ++   G R E G
Sbjct: 1365 GRKGDPGPSGPP-------GPRGPLGD----PGPRGPPG----LPGTAMKGDKGDRGERG 1409

Query: 959  PHGQSVAGLR-FEGQHNQLGGNLRFEGPHGQPG----VGIRFEGP--LVQQGGGMRFEGP 1011
            P G    G+   E     L G+   +GP G PG     G   +G   L  Q G    +GP
Sbjct: 1410 PPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGP 1469

Query: 1012 SVPGGGL------RIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGLHGQPGPRF-E 1064
              P G +         GPLG+ G + E        G PG P+      G+ G+PG +  E
Sbjct: 1470 RGPPGAIGPKGDRGFPGPLGEAGEKGE-------RGPPG-PAGSRGLPGVAGRPGAKGPE 1521

Query: 1065 RTPGQPGPQRFDGPPGQQVQPRFDG 1089
              PG  G Q   G PG+   P   G
Sbjct: 1522 GPPGPTGRQGEKGEPGRPGDPAVVG 1546



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 103/340 (30%), Positives = 130/340 (38%), Gaps = 81/340 (23%)

Query: 773  PNKLSPR-IDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP 831
            P +  PR + GPP        GS G+ G  G +   G +G  G    +   GPPGP G  
Sbjct: 2486 PGQEGPRGLTGPP--------GSRGERGEKGDVGSAGLKGDKGDSAVIL--GPPGPRGAK 2535

Query: 832  --LRFEGPIGQAGGGGFRFE-GSPGLR-FEGSPG--------GLR-FEGPGGQPVGGLRF 878
              +   GP G  G  G R + G PG +  +G PG        GLR   GP GQP G    
Sbjct: 2536 GDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQP-GAAGI 2594

Query: 879  EGHRGQP----VGGLRFEGPHGQPVGGLRFDNPRGQP-----VGGLRFEGGHGPSGAAIR 929
             G  G P    V G+R E       G + F  PRG        G    +G  G  G A  
Sbjct: 2595 PGDPGSPGKDGVPGIRGEK------GDVGFMGPRGLKGERGVKGACGLDGEKGDKGEA-- 2646

Query: 930  FDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLR----FEGQHNQLGGNLRFEGP 985
              GP G+PG     +G + + GV  +   P  + + G +    F+GQ    G     +G 
Sbjct: 2647 --GPPGRPGLA-GHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGE-KGE 2702

Query: 986  HGQPGVGIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQ 1045
             G PG+G               F GPS   G     GP G  GPR          G  G 
Sbjct: 2703 RGTPGIG--------------GFPGPSGNDGSAGPPGPPGSVGPR----------GPEG- 2737

Query: 1046 PSLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQP 1085
                    G  G+ GP  ER  G PG     G  G+Q +P
Sbjct: 2738 ------LQGQKGERGPPGERVVGAPGVPGAPGERGEQGRP 2771



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 119/358 (33%), Positives = 144/358 (40%), Gaps = 84/358 (23%)

Query: 772  GPNKLSPRIDGPPTPASLRFDGSPGQMGG---GGPLRFEGPQGQLGGGCPLRFEGPPGPV 828
            GP  L+ R  GPP  +     G PG+ G     GP    GP+G+ G       EGPPG  
Sbjct: 1595 GPIGLTGRA-GPPGDS-----GPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDP 1648

Query: 829  GTPLRFEGPIGQAGGGGFRFEGSPGLR----FEGSPGGLRFEGPGGQPVGGLRFEGHRGQ 884
            G P       G+AG  G R  G+PG+R     +G  G    +G  G P G    +G RG+
Sbjct: 1649 GLP-------GKAGERGLR--GAPGVRGPVGEKGDQGDPGEDGRNGSP-GSSGPKGDRGE 1698

Query: 885  PVGGLRFEGPHGQPVGGLRFDNP----RGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG-- 938
            P       GP G P G L    P    +G+P G    EG  GP G      G  G PG  
Sbjct: 1699 P-------GPPGPP-GRLVDTGPGAREKGEP-GDRGQEGPRGPKGD----PGLPGAPGER 1745

Query: 939  GGIRFEGPLLQQG-VGMRFEGPHGQ-SVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFE 996
            G   F GP   QG  G+R  GP G+    G       + L G     GP G  G   +  
Sbjct: 1746 GIEGFRGPPGPQGDPGVR--GPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAG 1803

Query: 997  GPLVQQGGGMRFE----GPSVPGGGLRIEGPLGQGG-PRFEGCHALRFDGQPGQPSLLPR 1051
             P      G+R E    GPS P G   + G  G+ G P   G      +G+PG P    R
Sbjct: 1804 DPGRDGLPGLRGEQGLPGPSGPPG---LPGKPGEDGKPGLNG-----KNGEPGDPGEDGR 1855

Query: 1052 --------FDGLHGQPGPRFER----------TPGQPGPQRFDGPPGQQVQPRFDGVP 1091
                      G  G+ GP+ ER           PG PGP    GPPGQ     F GVP
Sbjct: 1856 KGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPV---GPPGQ----GFPGVP 1906



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 140/464 (30%), Positives = 172/464 (37%), Gaps = 110/464 (23%)

Query: 754  GPSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQL 813
            GPS P      P +   +G   L+ +   P  P      G  G  G  G    +GP+G+ 
Sbjct: 1821 GPSGPPGLPGKPGE---DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGER 1877

Query: 814  GGGCPLRFEGP---PGPVGTPLR-FEGPIGQAGGGGFRFE-GSPGLRFEGSPG--GLRFE 866
            G    L  +GP   PGPVG P + F G  G  G  G R E GS G   +G PG  GLR E
Sbjct: 1878 GAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKG--EQGLPGERGLRGE 1935

Query: 867  GPGGQP-------VGGLRFEG--------------------HRGQPVGGLRFEGPHGQ-- 897
             PG  P         G++                        R  P G    +GP G+  
Sbjct: 1936 -PGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEG 1994

Query: 898  PVG-----GLRFD----NPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPG-GGIRFEGPL 947
            P+G     GL+ D     P+G P   L   G  GPSG A    G  G+PG  G+    P 
Sbjct: 1995 PIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLA----GEPGKPGIPGL----PG 2046

Query: 948  LQQGVGMRFE-GPHGQ-SVAGLRFEGQHNQLGGNLRFEGPHGQPG--VGIRFEGPLV--Q 1001
               GVG     G  G+    G R E   +   G     GP G PG  V +   GP +  +
Sbjct: 2047 RAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGE 2106

Query: 1002 QG-----------GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLP 1050
            QG           G    +GP    G   I+G  G+ GPR +       DG PG P    
Sbjct: 2107 QGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQ-------DGNPGLP---- 2155

Query: 1051 RFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLG 1110
               G  G  GP  E  PG  GP+   GP G    P   G P    GP   Q      P G
Sbjct: 2156 ---GERGMAGP--EGKPGLQGPRGPPGPVGGHGDPGPPGAP-GLAGPAGPQG-----PSG 2204

Query: 1111 LQGTRFDNHPSQRLESVSFNQTGPYN-----DPPGNAFNAPSQG 1149
            L+G   +  P  R        TGP        PPG +     QG
Sbjct: 2205 LKGEPGETGPPGR------GLTGPTGAVGLPGPPGPSGLVGPQG 2242



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 138/468 (29%), Positives = 169/468 (36%), Gaps = 102/468 (21%)

Query: 773  PNKLSPRID----GPPTPASLRFDGSPG--QMGGGGPLRFEGPQGQLGG----GCPLR-- 820
            P    P+ D    GPP P     D  PG  + G  G    EGP+G  G     G P    
Sbjct: 1687 PGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERG 1746

Query: 821  ---FEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGL----RFEGSPGGLRFEGPGGQPV 873
               F GPPGP G P    GP G+ G       G PGL      +G PG     GP G   
Sbjct: 1747 IEGFRGPPGPQGDP-GVRGPAGEKGD-----RGPPGLDGRSGLDGKPGAAGPSGPNG-AA 1799

Query: 874  GGLRFEGHRGQPVGGLRFE----GPHGQP----------VGGLRFDNPRGQPVGGLRFEG 919
            G     G  G P  GLR E    GP G P            GL   N      G    +G
Sbjct: 1800 GKAGDPGRDGLP--GLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKG 1857

Query: 920  GHGPSGAAIR--FDGPHGQ--------PGGGIRFEGPLLQQGVGMRFEG-PHGQSVAGLR 968
              G SGA+ R   DGP G+        P G     GP+   G G  F G P G    G R
Sbjct: 1858 EKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQG--FPGVPGGTGPKGDR 1915

Query: 969  FEGQHNQLGGNLRFEGPHGQPG-----------VGIRFEG--PLVQ---QGGGMRFEGPS 1012
             E       G     G  G+PG            GI+      +V+   +  G     P 
Sbjct: 1916 GETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPE 1975

Query: 1013 ---VPGGGLRIEGPLGQGGP-RFEGCHALRFD----GQPGQPSLL------PRFDGLHGQ 1058
                P G    +GP G+ GP  F G   L+ D    G  G P L       P   GL G+
Sbjct: 1976 RRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGE 2035

Query: 1059 PG-PRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFD 1117
            PG P     PG+ G     G PG++         +R +  +  +  R D P GL GT   
Sbjct: 2036 PGKPGIPGLPGRAGGVGEAGRPGER--------GERGEKGERGEQGR-DGPPGLPGT--P 2084

Query: 1118 NHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQGP 1165
              P      VS ++ G     PG +      GL+  + E   +  QGP
Sbjct: 2085 GPPGPPGPKVSVDEPG-----PGLSGEQGPPGLKGAKGEPGSNGDQGP 2127



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 105/360 (29%), Positives = 130/360 (36%), Gaps = 70/360 (19%)

Query: 749  RPLFDGPSRPSVARDGPT-KMIFEGPNKLSPRIDGPPTPASLR----FDGSPGQMGGGGP 803
            RP   GP  P   RDG   +   EGP    P + G      LR      G  G+ G  G 
Sbjct: 1620 RPGPPGPVGPR-GRDGEVGEKGDEGPPG-DPGLPGKAGERGLRGAPGVRGPVGEKGDQGD 1677

Query: 804  LRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGL 863
               +G  G  G   P    G PGP G P R         G G R +G PG R +  P G 
Sbjct: 1678 PGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDT-----GPGAREKGEPGDRGQEGPRGP 1732

Query: 864  RFE-GPGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHG 922
            + + G  G P G    EG RG P       GP G P  G+R   P G+       +G  G
Sbjct: 1733 KGDPGLPGAP-GERGIEGFRGPP-------GPQGDP--GVR--GPAGE-------KGDRG 1773

Query: 923  PSGAAIRFDGPHGQPGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRF 982
            P G   R  G  G+PG      GP    G   +   P    + GLR         G    
Sbjct: 1774 PPGLDGR-SGLDGKPGAA----GPSGPNGAAGKAGDPGRDGLPGLR---------GEQGL 1819

Query: 983  EGPHGQPGVGIRFEGPLVQQGGGMRFEGPSVPG--------GGLRIEGPLGQGGPRFEGC 1034
             GP G PG+  +  G   + G   +   P  PG        G     G  G+ GP+    
Sbjct: 1820 PGPSGPPGLPGK-PGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPK---- 1874

Query: 1035 HALRFDGQPGQPSLL-----PRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDG 1089
                  G+ G P +L     P   G  G PG  F   PG  GP+   G  G + +    G
Sbjct: 1875 ------GERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPG 1928



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 60/204 (29%), Positives = 78/204 (38%), Gaps = 44/204 (21%)

Query: 983  EGPHGQPG-VGIRFE-GPLVQQG--GGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALR 1038
            +G  G+PG +G+R + GP    G  G     GP  P G    +G  G  G          
Sbjct: 1253 KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGA--------- 1303

Query: 1039 FDGQPGQPSLLPRFDGLHGQPG-PRFERTPGQPGPQRFD----GPPGQQVQPRFDGVPQR 1093
             DG+PG P       G  G PG P  + +PG PGP R D    GP G + +P   G    
Sbjct: 1304 -DGRPGSPGRA----GNPGTPGAPGLKGSPGLPGP-RGDPGERGPRGPKGEPGAPGQVIG 1357

Query: 1094 FDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDP-PGNAFNAPSQGLQF 1152
             +GP            GL G + D  PS           GP  DP P      P   ++ 
Sbjct: 1358 GEGP------------GLPGRKGDPGPSG-----PPGPRGPLGDPGPRGPPGLPGTAMKG 1400

Query: 1153 QRHEQIFDSPQGPNFNG--PHGPG 1174
             + ++    P GP   G  P  PG
Sbjct: 1401 DKGDRGERGPPGPGEGGIAPGEPG 1424


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 111/346 (32%), Positives = 135/346 (39%), Gaps = 65/346 (18%)

Query: 782  GPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP--------LR 833
            GPP P      G PG MG  G +   GP G LG   P    G PG  G P        L 
Sbjct: 1065 GPPGPTG--DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLG 1122

Query: 834  FEGPIGQAGGGGFRFEGSPGL-RFEGSPGGLRFEGPGGQPVGGLRFEGHRGQPVGGLRF- 891
            F+G  G  G  G R  G PGL  F GSPG +   G  G+  G     G +G+  G LR  
Sbjct: 1123 FKGIKGLLGPPGIR--GPPGLPGFPGSPGPMGIRGDQGRD-GIPGPAGEKGE-TGLLRAP 1178

Query: 892  EGPHGQPVGGLRFDNPRGQP--------VGGLRFEGGHGPSGAAIRFDGPHGQPG----G 939
             GP G P G       RG P         G +   G  GP+G    F GP G PG    G
Sbjct: 1179 PGPRGNP-GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIE-GFPGPPGLPGAIIPG 1236

Query: 940  GIRFEGPLLQQGV--GMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEG 997
                 GP   +G        GP G  V G++ +       G++   GP G PG      G
Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD------KGSMGHPGPKGPPGTA----G 1286

Query: 998  PLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRF----- 1052
             +   G   R   P  PG    + GP  +G P F+G   ++  G+ G P  L        
Sbjct: 1287 DMGPPG---RLGAPGTPG----LPGP--RGDPGFQGFPGVK--GEKGNPGFLGSIGPPGP 1335

Query: 1053 ------DGLHGQPGP-RFERTPGQPGPQRFDGPPGQQVQPRFDGVP 1091
                   G+ G PG  +    PG PGP    G PG Q +P   G P
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 133/442 (30%), Positives = 167/442 (37%), Gaps = 86/442 (19%)

Query: 772  GPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP 831
            GP+++S  I     P    F G+PG+ G  G     G +G          +G PGP G P
Sbjct: 943  GPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKG---------LKGLPGPAGPP 993

Query: 832  LRFEGPIGQAGGGGFRFEGSPGLR-FEGSPGGLRFEGPGGQPVGGLRFEGHRGQP-VGGL 889
                GP G  G  G    G PGLR   GS G +   G  G+  G L F G  G+P + G+
Sbjct: 994  ----GPRGDLGSTG--NPGEPGLRGIPGSMGNMGMPGSKGKR-GTLGFPGRAGRPGLPGI 1046

Query: 890  R-FEGPHGQP--VGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQ--PGGGIRFE 944
               +G  G+P    G R   P G P G     G  G  G  +   GP G   P G     
Sbjct: 1047 HGLQGDKGEPGYSEGTR-PGPPG-PTGDPGLPGDMGKKG-EMGQPGPPGHLGPAGPEGAP 1103

Query: 945  GPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPG-------VGIR--- 994
            G     G+  +  GPHG     L F+G    LG      GP G PG       +GIR   
Sbjct: 1104 GSPGSPGLPGK-PGPHGD----LGFKGIKGLLGPP-GIRGPPGLPGFPGSPGPMGIRGDQ 1157

Query: 995  ----FEGPLVQQGGGMRFEGPSVPGGGLRIEGPLG-QGGPRFEGCHALR----------- 1038
                  GP  ++G       P  P G    +G  G +G P F G    +           
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP 1217

Query: 1039 -----FDGQPGQP-SLLPRFDGLHGQPGPRFERTPGQPGPQRFDGPPGQQVQPRFDGVPQ 1092
                 F G PG P +++P   G  G PG R   +PG PGP    GPPG  V     G+  
Sbjct: 1218 TGIEGFPGPPGLPGAIIPGQTGNRGPPGSR--GSPGAPGP---PGPPGSHV----IGIKG 1268

Query: 1093 RFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSF-NQTGPYNDPPGNAFNAPSQGLQ 1151
                  H        P G  GT  D  P  RL +       GP  DP    F     G++
Sbjct: 1269 DKGSMGHPG------PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGF----PGVK 1318

Query: 1152 FQRHEQIFDSPQGPNFNGPHGP 1173
             ++    F    GP   GP GP
Sbjct: 1319 GEKGNPGFLGSIGP--PGPIGP 1338



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 132/443 (29%), Positives = 164/443 (37%), Gaps = 78/443 (17%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGP------------- 824
            P  DG P    + F G PG  G  G   F G +G L  GCP +   P             
Sbjct: 688  PGPDGEPGIPGIGFPGPPGPKGDQG---FPGTKGSL--GCPGKMGEPGLPGKPGLPGAKG 742

Query: 825  ------PGPVGTPLRFEGPIGQAG-GGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLR 877
                  PG  GTP  F G  G +G  G     G PGL   G+PG    +GP G P G   
Sbjct: 743  EPAVAMPGGPGTP-GFPGERGNSGEHGEIGLPGLPGL--PGTPGNEGLDGPRGDP-GQPG 798

Query: 878  FEGHRGQPVGGLRFEGPHG-QPVGGLRFDNPRGQPVGGLRFEGGHGPSG-------AAIR 929
              G +G P  G   EGP G Q + GL  +  +GQ   G R  G  GP G           
Sbjct: 799  PPGEQGPP--GRCIEGPRGAQGLPGL--NGLKGQQ--GRR--GKTGPKGDPGIPGLDRSG 850

Query: 930  FDGPHGQPG--GGIRFEGPLLQQGV--GMRFEGPHGQS--VAGLRFEGQHNQLG--GNLR 981
            F G  G PG  G     GPL Q+G        GP G+   +  + F G     G  GN  
Sbjct: 851  FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910

Query: 982  FEGPHGQPGV-GIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPR-FEGCHALRF 1039
              G  G PG+ G++ +       G    +G   P     + G  G+ G + F G    + 
Sbjct: 911  TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970

Query: 1040 D-GQPGQPSL--LPRFDGLHGQPGPRFE----RTPGQPGPQRFDGPPGQQVQPRFDGVPQ 1092
            + G PG P L  L    G  G PGPR +      PG+PG +   G  G    P   G   
Sbjct: 971  NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030

Query: 1093 RFDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDP--PGNAFNAPSQGL 1150
                P   +A R  +P G+ G + D       E       GP  DP  PG+       G 
Sbjct: 1031 TLGFP--GRAGRPGLP-GIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMG- 1086

Query: 1151 QFQRHEQIFDSPQGPNFNGPHGP 1173
                       P  P   GP GP
Sbjct: 1087 ----------QPGPPGHLGPAGP 1099



 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 134/465 (28%), Positives = 165/465 (35%), Gaps = 136/465 (29%)

Query: 778  PRIDGPPTPASLRFDGSPGQMGGGGP----------------------------LRFEGP 809
            P  D   TP S    GSPG  G  GP                               +GP
Sbjct: 409  PGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP 468

Query: 810  QGQLG---GGCPLRFEGPPGPVGTP--LRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLR 864
            +G+ G     CP    GPPG  G P     +G  G+ G  G +  GSP     GSPG   
Sbjct: 469  KGEPGLLCTQCPY-IPGPPGLPGLPGLHGVKGIPGRQGAAGLK--GSP-----GSPGNTG 520

Query: 865  FEG----PGGQPVGGLRFE-----------------GHRGQPVGGLRFEGPHGQPVGGLR 903
              G    PG Q   GL+ E                 G RGQP G    +G  G P G   
Sbjct: 521  LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP-GRKGLDGIPGTP-GVKG 578

Query: 904  FDNPRGQ-----------PVGGLRFEGGHGPSG-AAIRFDGPHGQPG-----------GG 940
               P+G+           P G     G  GP+G A     GP G+PG           G 
Sbjct: 579  LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638

Query: 941  IRFEGPLLQQGVGMRFEGPHG----------QSVAGLRFEGQHNQLG--GNLRFEGPHGQ 988
                GP  +  V     GP G          Q   G+        LG  G+    GP G+
Sbjct: 639  PGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGI-----PGSLGKCGDPGLPGPDGE 693

Query: 989  PGV-GIRFEGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGG-------PRFEGCHALRFD 1040
            PG+ GI F GP   +G     +G     G L   G +G+ G       P  +G  A+   
Sbjct: 694  PGIPGIGFPGPPGPKGD----QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749

Query: 1041 GQPGQPSLLPR--FDGLHGQPG-PRFERTPGQPGPQRFDGP---PGQQVQPRFDGVPQR- 1093
            G PG P         G HG+ G P     PG PG +  DGP   PGQ   P   G P R 
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 1094 FDGPQHQQASRFDIPLGLQGTRFDNHPSQRLESVSFNQTGPYNDP 1138
             +GP+  Q     +P GL G +      +R       +TGP  DP
Sbjct: 810  IEGPRGAQG----LP-GLNGLK--GQQGRR------GKTGPKGDP 841



 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 114/363 (31%), Positives = 139/363 (38%), Gaps = 66/363 (18%)

Query: 782  GPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQA 841
            GPP        GSPGQ G  GP    GPQG  G      F G PG  G+    +G  G +
Sbjct: 55   GPP--------GSPGQKGFTGPEGLPGPQGPKG------FPGLPGLTGS----KGVRGIS 96

Query: 842  GGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP--VGGLRFEGPHGQPV 899
            G  GF   GSPGL   G+PG     G  G P G    +G +G P   G L + G  G   
Sbjct: 97   GLPGF--SGSPGL--PGTPGNTGPYGLVGVP-GCSGSKGEQGFPGLPGTLGYPGIPG--A 149

Query: 900  GGLRFDNPRGQPV----------GGLRFEGGHGPSG--AAIRFDGPHGQPG--GGIRFEG 945
             GL+    +G P           G     G  GP G      F GP G PG  G   F G
Sbjct: 150  AGLK--GQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG 207

Query: 946  PLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPG-VGIRFEGPLVQQGG 1004
             +  +G     +G  G+ V G      H    G     GP G PG V +   GP      
Sbjct: 208  AMGPRGP----KGHMGERVIG------HKGERGVKGLTGPPGPPGTVIVTLTGP----DN 253

Query: 1005 GMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLL--PRFDGLHGQPGPR 1062
                +G     G +   GP G  G   E   + +  G PG P L   P  DG+ G PG  
Sbjct: 254  RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEK--GAPGDPGLQGKPGKDGVPGFPGSE 311

Query: 1063 -FERTPGQPGPQRFDGPPGQQVQ---PRFDGVPQRFDGPQHQQASRFDIPLGLQGTRFDN 1118
              +   G PG    DG  GQ+     P F G  + +D  Q +       P G +G R   
Sbjct: 312  GVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQ 371

Query: 1119 HPS 1121
             PS
Sbjct: 372  GPS 374



 Score = 74.3 bits (181), Expect = 8e-13
 Identities = 108/356 (30%), Positives = 134/356 (37%), Gaps = 81/356 (22%)

Query: 793  GSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSP 852
            G PG  G  G   F GP+G  G   P  F G PG  G+    +G  G +G  G  F GSP
Sbjct: 52   GFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGS----KGVRGISGLPG--FSGSP 105

Query: 853  GLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP--VGGLRFEGPHGQPVGGLRFDNPRGQ 910
            GL   G+PG     G  G P G    +G +G P   G L + G  G    GL+    +G 
Sbjct: 106  GL--PGTPGNTGPYGLVGVP-GCSGSKGEQGFPGLPGTLGYPGIPG--AAGLK--GQKGA 158

Query: 911  PV----------GGLRFEGGHGPSG--AAIRFDGPHGQPG--GGIRFEGPLLQQG----- 951
            P           G     G  GP G      F GP G PG  G   F G +  +G     
Sbjct: 159  PAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 952  ----VGMRFE----------GPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFEG 997
                +G + E          GP G  +  L        L G    +G  G+PG      G
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP----PG 274

Query: 998  P--LVQQGGGMRFEGPSVPGGGLRIEGPLGQGG-PRFEGCHALRFDGQPGQPSLLPRFDG 1054
            P  L  +  G     P  PG    ++G  G+ G P F G   ++  G  G P L+   DG
Sbjct: 275  PSGLPGESYGSEKGAPGDPG----LQGKPGKDGVPGFPGSEGVK--GNRGFPGLMGE-DG 327

Query: 1055 LHGQPG----PRF---------------ERTPGQPGPQRFDGPPGQQVQPRFDGVP 1091
            + GQ G    P F               E TPG PGP+   GP G    P   G P
Sbjct: 328  IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSP 383



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 110/342 (32%), Positives = 124/342 (36%), Gaps = 64/342 (18%)

Query: 777  SPRIDGPPTPASLRFD-----GSPGQMGGGGPLRFEGPQGQLG---GGCPLRFEGPPGPV 828
            SP   GPP     R       G PG +G  G    +GP+G+ G     CP    GPPG  
Sbjct: 431  SPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY-IPGPPGLP 489

Query: 829  GTP--LRFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEG----PGGQPVGGLRFE-GH 881
            G P     +G  G+ G  G +  GSPG     SPG     G    PG Q   GL+ E G 
Sbjct: 490  GLPGLHGVKGIPGRQGAAGLK--GSPG-----SPGNTGLPGFPGFPGAQGDPGLKGEKGE 542

Query: 882  RGQPVGGLRFEGP---HGQPVGGLRFDNPRGQP-VGGLRFEGGHGPSGAAIRFDGPHGQP 937
              QP G +   G     GQP G    D   G P V GL    G           GP G P
Sbjct: 543  TLQPEGQVGVPGDPGLRGQP-GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDP 601

Query: 938  G--GGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRF 995
            G  G     GP    G G     P G+             L G     G  G PG     
Sbjct: 602  GSPGSPGPAGPAGPPGYG-----PQGEP-----------GLQGTQGVPGAPGPPGEA--- 642

Query: 996  EGPLVQQGGGMRFEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQPGQPSLLPRFDGL 1055
             GP  +        GP  P G     GP  QG P   G  +L   G PG    LP  DG 
Sbjct: 643  -GPRGELSVSTPVPGPPGPPGPPGHPGP--QGPPGIPG--SLGKCGDPG----LPGPDGE 693

Query: 1056 HGQPGPRFERTPGQPGPQRFDGP------PGQQVQPRFDGVP 1091
             G PG  F   PG  G Q F G       PG+  +P   G P
Sbjct: 694  PGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKP 735



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 103/327 (31%), Positives = 122/327 (37%), Gaps = 50/327 (15%)

Query: 783  PPTPASLRFDGSPGQMG----GGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTP--LRFEG 836
            P  P +L + G PG  G     G P + E  +    G   L   G PGP G P    F G
Sbjct: 135  PGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGL--PGAPGPQGLPGPPGFPG 192

Query: 837  PIGQAGGGGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFEGHRGQP-VGGLRFE-GP 894
            P+G  G  GF           G PG +   GP G    G R  GH+G+  V GL    GP
Sbjct: 193  PVGPPGPPGFF----------GFPGAMGPRGPKGHM--GERVIGHKGERGVKGLTGPPGP 240

Query: 895  HGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQPGGGIRFE-----GPLLQ 949
             G  +  L   + R    G    +G  G  G      GP G PG     E      P LQ
Sbjct: 241  PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP----GPSGLPGESYGSEKGAPGDPGLQ 296

Query: 950  QGVGMRFEG----PHGQSVAGLR-FEGQHNQLGGNLRFEGPHGQPGVGIRFEGPL----- 999
               G   +G    P  + V G R F G   + G   + +G  G PG    F GP      
Sbjct: 297  GKPGK--DGVPGFPGSEGVKGNRGFPGLMGEDGIKGQ-KGDIGPPG----FRGPTEYYDT 349

Query: 1000 VQQGGGMRFEGPSVPGGGLRIEGPLGQGG-PRFEGCHALRFDGQPGQPSLLPRFDGLHGQ 1058
             Q+ G     GP  P G    +GP G  G P   G       G PG P L     G  G+
Sbjct: 350  YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGS-KGERGR 408

Query: 1059 PGPRFERTPGQPGPQRFDGPPGQQVQP 1085
            PG     TPG PG     G PG    P
Sbjct: 409  PGKDAMGTPGSPGCAGSPGLPGSPGPP 435



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 141/501 (28%), Positives = 176/501 (35%), Gaps = 109/501 (21%)

Query: 775  KLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPLRF 834
            K  P +  P  P +  F G  G  G  G +   G  G  G       +GP G  G P   
Sbjct: 741  KGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQP--- 797

Query: 835  EGPIGQAGGGGFRFEGS------PGLR-FEGSPGGLRFEGPGGQP-VGGL---RFEGHRG 883
             GP G+ G  G   EG       PGL   +G  G     GP G P + GL    F G  G
Sbjct: 798  -GPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 884  QP-VGGLRFE-GPHGQP--VGGLRFDNPRGQP--VGGLRFEGGHGPSGAAIRFDGPHGQP 937
             P + G + E GP GQ    G      P G+   +G + F G  GP        GP G P
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGP-------PGPPGNP 909

Query: 938  G-----GGIRFEGPLLQQGV-GMRFE----GPHGQS----VAGLRFEGQHNQLGGNLRFE 983
            G     G     G   Q+G  G + E    G  G S    V G + E       GN   +
Sbjct: 910  GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969

Query: 984  GPHGQPGV-GIR----FEGPLVQQG--GGMRFEG-PSVPG--------GGLRIEGPLGQ- 1026
            G  G PG+ G++      GP    G  G +   G P  PG        G + + G  G+ 
Sbjct: 970  GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR 1029

Query: 1027 ---------GGPRFEGCHALRFD------------------GQPGQPSLLPRFDGLHGQP 1059
                     G P   G H L+ D                  G PG P  + +  G  GQP
Sbjct: 1030 GTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK-KGEMGQP 1088

Query: 1060 GPRF-------ERTPGQPGPQRFDGPPGQQVQPRFDGV-----PQRFDGPQHQQA-SRFD 1106
            GP         E  PG PG     G PG      F G+     P    GP          
Sbjct: 1089 GPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSP 1148

Query: 1107 IPLGLQGTR-FDNHPSQRLESVSFNQTGPYNDPPGNAFNAPSQGLQFQRHEQIFDSPQG- 1164
             P+G++G +  D  P    E     +TG    PPG   N  +QG +  R    F    G 
Sbjct: 1149 GPMGIRGDQGRDGIPGPAGEK---GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGR 1205

Query: 1165 ---PNFNGPHGP-GNQSFSNP 1181
                   GP GP G + F  P
Sbjct: 1206 KGAMGDAGPRGPTGIEGFPGP 1226



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 65/190 (34%), Positives = 77/190 (40%), Gaps = 28/190 (14%)

Query: 755  PSRPSVARDGPTKMIFEGPNKLSPRIDGPPTPAS---LRFDGSPGQMGGGGPLRFEGPQG 811
            P  P     G T       ++ SP   GPP P     +   G  G MG  GP   +GP G
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGP---KGPPG 1283

Query: 812  QLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFEGSPGLRFE-GSPGGLRFEGPGG 870
              G   P    G PG  G P    GP G  G     F+G PG++ E G+PG L   GP G
Sbjct: 1284 TAGDMGPPGRLGAPGTPGLP----GPRGDPG-----FQGFPGVKGEKGNPGFLGSIGPPG 1334

Query: 871  QPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRF 930
             P+G     G RG P G L+     G P        P G P G    +G  GP G     
Sbjct: 1335 -PIGPKGPPGVRGDP-GTLKIISLPGSP-------GPPGTP-GEPGMQGEPGPPGPPGNL 1384

Query: 931  D--GPHGQPG 938
               GP G+PG
Sbjct: 1385 GPCGPRGKPG 1394



 Score = 38.9 bits (89), Expect = 0.039
 Identities = 35/97 (36%), Positives = 37/97 (38%), Gaps = 18/97 (18%)

Query: 754  GPSRPSVARDGP-TKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQ 812
            GP  P   R  P T  I   P    P    P TP      G PG  G  GP    GP G 
Sbjct: 1337 GPKGPPGVRGDPGTLKIISLPGSPGP----PGTP------GEPGMQGEPGP---PGPPGN 1383

Query: 813  LGGGCPLRFEGPPGPVGTPLRFEGPIGQAGGGGFRFE 849
            LG   P    G  G  GTP    GP G+ G  G + E
Sbjct: 1384 LGPCGPRGKPGKDGKPGTP----GPAGEKGNKGSKGE 1416


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,313,413
Number of Sequences: 37866
Number of extensions: 4505866
Number of successful extensions: 33173
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 234
Number of HSP's successfully gapped in prelim test: 1149
Number of HSP's that attempted gapping in prelim test: 15740
Number of HSP's gapped (non-prelim): 6715
length of query: 1555
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1439
effective length of database: 13,855,062
effective search space: 19937434218
effective search space used: 19937434218
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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