Guide to the Human Genome
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Name: BRAF Sequence: fasta or formatted (766aa) NCBI GI: 33188459
Description:

B-Raf

Referenced in:

MAP Kinase Pathways
Ras

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.8         52           3
 C cysteine            1.7         13           2
 D aspartate           5.1         39           2
 E glutamate           5.5         42           2
 F phenylalanine       4.3         33           2
 G glycine             7.3         56           6
 H histidine           2.6         20           2
 I isoleucine          5.6         43           2
 K lysine              5.4         41           3
 L leucine             8.9         68           2
 M methionine          2.3         18           2
 N asparagine          3.5         27           2
 P proline             6.7         51           2
 Q glutamine           5.4         41           2
 R arginine            5.2         40           2
 S serine             10.2         78           6
 T threonine           5.1         39           2
 V valine              5.2         40           2
 W tryptophan          1.0          8           1
 Y tyrosine            2.2         17           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   B-Raf 
RAF1                  0.440   v-raf-1 murine leukemia viral oncogene homolog 1 [Hom...
ARAF                  0.430   v-raf murine sarcoma 3611 viral oncogene homolog [Hom...
KSR2                  0.117   kinase suppressor of ras 2 
KSR1                  0.111   kinase suppressor of ras 
MAP3K12               0.085   mitogen-activated protein kinase kinase kinase 12 [H...
MAP3K13               0.081   mitogen-activated protein kinase kinase kinase 13 [Ho...
FYN                   0.078   protein-tyrosine kinase fyn isoform a 
FRK                   0.078   fyn-related kinase 
SRC                   0.078   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.078   proto-oncogene tyrosine-protein kinase SRC 
YES1                  0.077   viral oncogene yes-1 homolog 1 
LCK                   0.077   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.077   lymphocyte-specific protein tyrosine kinase precurs...
LYN                   0.077   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
LYN                   0.077   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
HCK                   0.075   hemopoietic cell kinase isoform p61HCK 
FYN                   0.074   protein-tyrosine kinase fyn isoform b 
PTK6                  0.074   PTK6 protein tyrosine kinase 6 
EPHA3                 0.073   ephrin receptor EphA3 isoform a precursor 
FGR                   0.072   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.072   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.072   proto-oncogene tyrosine-protein kinase FGR 
EPHA8                 0.072   ephrin receptor EphA8 isoform 1 precursor 
BLK                   0.072   B lymphoid tyrosine kinase 
EPHB4                 0.070   EPH receptor B4 precursor 
EPHA4                 0.069   ephrin receptor EphA4 
EPHB1                 0.069   ephrin receptor EphB1 precursor 
EPHA5                 0.068   ephrin receptor EphA5 isoform b precursor 
EPHA5                 0.068   ephrin receptor EphA5 isoform a precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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