Guide to the Human Genome
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Name: BLK Sequence: fasta or formatted (505aa) NCBI GI: 33469982
Description:

B lymphoid tyrosine kinase

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.7         34           2
 C cysteine            1.6          8           2
 D aspartate           4.8         24           1
 E glutamate           8.3         42           2
 F phenylalanine       3.8         19           2
 G glycine             6.3         32           2
 H histidine           1.6          8           1
 I isoleucine          4.8         24           2
 K lysine              6.5         33           2
 L leucine             9.9         50           2
 M methionine          3.0         15           1
 N asparagine          2.6         13           2
 P proline             6.9         35           4
 Q glutamine           4.0         20           1
 R arginine            6.9         35           1
 S serine              5.5         28           2
 T threonine           4.4         22           2
 V valine              6.5         33           2
 W tryptophan          2.0         10           2
 Y tyrosine            4.0         20           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   B lymphoid tyrosine kinase 
HCK                   0.622   hemopoietic cell kinase isoform p61HCK 
LCK                   0.604   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.604   lymphocyte-specific protein tyrosine kinase precurs...
LYN                   0.603   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
LYN                   0.601   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
FYN                   0.541   protein-tyrosine kinase fyn isoform a 
FYN                   0.529   protein-tyrosine kinase fyn isoform b 
YES1                  0.528   viral oncogene yes-1 homolog 1 
SRC                   0.524   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.524   proto-oncogene tyrosine-protein kinase SRC 
FGR                   0.516   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.516   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.516   proto-oncogene tyrosine-protein kinase FGR 
FYN                   0.461   protein-tyrosine kinase fyn isoform c 
FRK                   0.418   fyn-related kinase 
SRMS                  0.326   src-related kinase lacking C-terminal regulatory tyr...
ABL2                  0.316   arg tyrosine kinase isoform c 
ABL2                  0.316   arg tyrosine kinase isoform b 
ABL2                  0.316   arg tyrosine kinase isoform e 
ABL2                  0.316   arg tyrosine kinase isoform d 
ABL2                  0.316   arg tyrosine kinase isoform a 
ABL1                  0.312   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.312   c-abl oncogene 1, receptor tyrosine kinase isoform b...
PTK6                  0.303   PTK6 protein tyrosine kinase 6 
TEC                   0.296   tec protein tyrosine kinase 
TXK                   0.295   TXK tyrosine kinase 
BTK                   0.292   Bruton agammaglobulinemia tyrosine kinase 
ITK                   0.278   IL2-inducible T-cell kinase 
CSK                   0.266   c-src tyrosine kinase 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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