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Search of human proteins with 32967603
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32967603 bromodomain adjacent to zinc finger domain, 1A
isoform a [Homo sapiens]
(1556 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 3095 0.0
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 3016 0.0
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 235 3e-61
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 116 2e-25
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 110 8e-24
gi|153791535 general control of amino acid synthesis 5-like 2 [H... 74 1e-12
gi|164419758 bromodomain containing 2 [Homo sapiens] 74 1e-12
gi|4826806 bromodomain containing 2 [Homo sapiens] 74 1e-12
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 73 2e-12
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 73 2e-12
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 71 9e-12
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 71 9e-12
gi|38788260 bromodomain PHD finger transcription factor isoform ... 69 5e-11
gi|38788274 bromodomain PHD finger transcription factor isoform ... 69 5e-11
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 68 6e-11
gi|50345997 E1A binding protein p300 [Homo sapiens] 66 2e-10
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 66 2e-10
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 66 2e-10
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 66 2e-10
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 66 2e-10
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 66 3e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 66 3e-10
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 65 4e-10
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 65 4e-10
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 65 7e-10
gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive ... 65 7e-10
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 65 7e-10
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 65 7e-10
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 65 7e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 64 9e-10
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 3095 bits (8023), Expect = 0.0
Identities = 1556/1556 (100%), Positives = 1556/1556 (100%)
Query: 1 MPLLHRKPFVRQKPPADLRPDEEVFYCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRP 60
MPLLHRKPFVRQKPPADLRPDEEVFYCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRP
Sbjct: 1 MPLLHRKPFVRQKPPADLRPDEEVFYCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRP 60
Query: 61 GLTYQEALESEKKARQNLQSFPEPLIIPVLYLTSLTHRSRLHEICDDIFAYVKDRYFVEE 120
GLTYQEALESEKKARQNLQSFPEPLIIPVLYLTSLTHRSRLHEICDDIFAYVKDRYFVEE
Sbjct: 61 GLTYQEALESEKKARQNLQSFPEPLIIPVLYLTSLTHRSRLHEICDDIFAYVKDRYFVEE 120
Query: 121 TVEVIRNNGARLQCRILEVLPPSHQNGFANGHVNSVDGETIIISDSDDSETQSCSFQNGK 180
TVEVIRNNGARLQCRILEVLPPSHQNGFANGHVNSVDGETIIISDSDDSETQSCSFQNGK
Sbjct: 121 TVEVIRNNGARLQCRILEVLPPSHQNGFANGHVNSVDGETIIISDSDDSETQSCSFQNGK 180
Query: 181 KKDAIDPLLFKYKVQPTKKELHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGVIK 240
KKDAIDPLLFKYKVQPTKKELHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGVIK
Sbjct: 181 KKDAIDPLLFKYKVQPTKKELHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGVIK 240
Query: 241 IKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASY 300
IKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASY
Sbjct: 241 IKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASY 300
Query: 301 RSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEER 360
RSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEER
Sbjct: 301 RSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEER 360
Query: 361 LKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRL 420
LKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRL
Sbjct: 361 LKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRL 420
Query: 421 PPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLEVLEEALVGNDSEGPLCELLFFFLTA 480
PPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLEVLEEALVGNDSEGPLCELLFFFLTA
Sbjct: 421 PPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLEVLEEALVGNDSEGPLCELLFFFLTA 480
Query: 481 IFQAIAEEEEEVAKEQLTDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLK 540
IFQAIAEEEEEVAKEQLTDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLK
Sbjct: 481 IFQAIAEEEEEVAKEQLTDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLK 540
Query: 541 SLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKL 600
SLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKL
Sbjct: 541 SLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKL 600
Query: 601 SSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKER 660
SSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKER
Sbjct: 601 SSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKER 660
Query: 661 EEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDT 720
EEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDT
Sbjct: 661 EEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDT 720
Query: 721 EQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQ 780
EQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQ
Sbjct: 721 EQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQ 780
Query: 781 EHQRKEKELLEKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDYSGLTEDMLLPR 840
EHQRKEKELLEKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDYSGLTEDMLLPR
Sbjct: 781 EHQRKEKELLEKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDYSGLTEDMLLPR 840
Query: 841 PSSFQNNVQSQDPQVSTKTGEPLMSESTSNIDQGPRDHSVQLPKPVHKPNRWCFYSSCEQ 900
PSSFQNNVQSQDPQVSTKTGEPLMSESTSNIDQGPRDHSVQLPKPVHKPNRWCFYSSCEQ
Sbjct: 841 PSSFQNNVQSQDPQVSTKTGEPLMSESTSNIDQGPRDHSVQLPKPVHKPNRWCFYSSCEQ 900
Query: 901 LDQLIEALNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRS 960
LDQLIEALNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRS
Sbjct: 901 LDQLIEALNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRS 960
Query: 961 SNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSE 1020
SNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSE
Sbjct: 961 SNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSE 1020
Query: 1021 ENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSSVVHYL 1080
ENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSSVVHYL
Sbjct: 1021 ENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSSVVHYL 1080
Query: 1081 AMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSV 1140
AMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSV
Sbjct: 1081 AMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSV 1140
Query: 1141 IWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQR 1200
IWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQR
Sbjct: 1141 IWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQR 1200
Query: 1201 SRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSL 1260
SRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSL
Sbjct: 1201 SRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSL 1260
Query: 1261 PKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINS 1320
PKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINS
Sbjct: 1261 PKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINS 1320
Query: 1321 APPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVI 1380
APPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVI
Sbjct: 1321 APPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVI 1380
Query: 1381 ATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQ 1440
ATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQ
Sbjct: 1381 ATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQ 1440
Query: 1441 LVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIEL 1500
LVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIEL
Sbjct: 1441 LVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIEL 1500
Query: 1501 MFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAAKKSRI 1556
MFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAAKKSRI
Sbjct: 1501 MFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAAKKSRI 1556
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 3016 bits (7820), Expect = 0.0
Identities = 1524/1556 (97%), Positives = 1524/1556 (97%), Gaps = 32/1556 (2%)
Query: 1 MPLLHRKPFVRQKPPADLRPDEEVFYCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRP 60
MPLLHRKPFVRQKPPADLRPDEEVFYCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRP
Sbjct: 1 MPLLHRKPFVRQKPPADLRPDEEVFYCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRP 60
Query: 61 GLTYQEALESEKKARQNLQSFPEPLIIPVLYLTSLTHRSRLHEICDDIFAYVKDRYFVEE 120
GLTYQEALESEKKARQNLQSFPEPLIIPVLYLTSLTHRSRLHEICDDIFAYVKDRYFVEE
Sbjct: 61 GLTYQEALESEKKARQNLQSFPEPLIIPVLYLTSLTHRSRLHEICDDIFAYVKDRYFVEE 120
Query: 121 TVEVIRNNGARLQCRILEVLPPSHQNGFANGHVNSVDGETIIISDSDDSETQSCSFQNGK 180
TVEVIRNNGARLQCRILEVLPPSHQNGFANGHVNSVDGETIIISDSDDSETQSCSFQNGK
Sbjct: 121 TVEVIRNNGARLQCRILEVLPPSHQNGFANGHVNSVDGETIIISDSDDSETQSCSFQNGK 180
Query: 181 KKDAIDPLLFKYKVQPTKKELHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGVIK 240
KKDAIDPLLFKYKVQPTKKELHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGVIK
Sbjct: 181 KKDAIDPLLFKYKVQPTKKELHESAIVKATQISRRKHLFSRDKLKLFLKQHCEPQDGVIK 240
Query: 241 IKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASY 300
IKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASY
Sbjct: 241 IKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASY 300
Query: 301 RSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEER 360
RSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEER
Sbjct: 301 RSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEER 360
Query: 361 LKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRL 420
LKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRL
Sbjct: 361 LKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRL 420
Query: 421 PPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLEVLEEALVGNDSEGPLCELLFFFLTA 480
PPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLEVLEEALVGNDSEGPLCELLFFFLTA
Sbjct: 421 PPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLEVLEEALVGNDSEGPLCELLFFFLTA 480
Query: 481 IFQAIAEEEEEVAKEQLTDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLK 540
IFQAIAEEEEEVAKEQLTDADTK GCSLK
Sbjct: 481 IFQAIAEEEEEVAKEQLTDADTK--------------------------------GCSLK 508
Query: 541 SLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKL 600
SLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKL
Sbjct: 509 SLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKL 568
Query: 601 SSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKER 660
SSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKER
Sbjct: 569 SSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKER 628
Query: 661 EEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDT 720
EEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDT
Sbjct: 629 EEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDT 688
Query: 721 EQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQ 780
EQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQ
Sbjct: 689 EQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQ 748
Query: 781 EHQRKEKELLEKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDYSGLTEDMLLPR 840
EHQRKEKELLEKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDYSGLTEDMLLPR
Sbjct: 749 EHQRKEKELLEKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDYSGLTEDMLLPR 808
Query: 841 PSSFQNNVQSQDPQVSTKTGEPLMSESTSNIDQGPRDHSVQLPKPVHKPNRWCFYSSCEQ 900
PSSFQNNVQSQDPQVSTKTGEPLMSESTSNIDQGPRDHSVQLPKPVHKPNRWCFYSSCEQ
Sbjct: 809 PSSFQNNVQSQDPQVSTKTGEPLMSESTSNIDQGPRDHSVQLPKPVHKPNRWCFYSSCEQ 868
Query: 901 LDQLIEALNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRS 960
LDQLIEALNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRS
Sbjct: 869 LDQLIEALNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRS 928
Query: 961 SNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSE 1020
SNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSE
Sbjct: 929 SNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSE 988
Query: 1021 ENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSSVVHYL 1080
ENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSSVVHYL
Sbjct: 989 ENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSSVVHYL 1048
Query: 1081 AMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSV 1140
AMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSV
Sbjct: 1049 AMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSV 1108
Query: 1141 IWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQR 1200
IWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQR
Sbjct: 1109 IWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQR 1168
Query: 1201 SRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSL 1260
SRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSL
Sbjct: 1169 SRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSL 1228
Query: 1261 PKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINS 1320
PKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINS
Sbjct: 1229 PKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINS 1288
Query: 1321 APPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVI 1380
APPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVI
Sbjct: 1289 APPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVI 1348
Query: 1381 ATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQ 1440
ATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQ
Sbjct: 1349 ATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQ 1408
Query: 1441 LVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIEL 1500
LVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIEL
Sbjct: 1409 LVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIEL 1468
Query: 1501 MFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAAKKSRI 1556
MFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAAKKSRI
Sbjct: 1469 MFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAAKKSRI 1524
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 235 bits (599), Expect = 3e-61
Identities = 264/1042 (25%), Positives = 431/1042 (41%), Gaps = 211/1042 (20%)
Query: 279 PPKRIHI-----SQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKAD 333
PP +H+ +D + L+ SK + LL E+ L E L +++ +
Sbjct: 472 PPAALHLIAYYKENKDREDKRSALSCVISKTAR----LLSSEDRARLPEELRSLVQKRYE 527
Query: 334 ALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLK 393
LE KK+ E++R+E K EE KK+ KE+ K REKE + E++++Y
Sbjct: 528 LLEHKKRWASMSEEQRKEYLKKKREEL--KKKLKEKAKERREKEMLERLEKQKRY----- 580
Query: 394 QWSKPREDMECDDLKELPEPTPVKTR--LPPEIFGDALMVLEFLNAFGELFDLQDEFPDG 451
ED E K LP V T LP +FGD MV+EFL+ + L ++P
Sbjct: 581 ------EDQELTG-KNLPAFRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYP-- 631
Query: 452 VTLEVLEEALVGNDSEGPLCELLFFFLTAIFQAIAEEEEEVAKEQLTDADTKDLTEALDE 511
+T L EAL D G L L L + Q + ++E
Sbjct: 632 ITAVSLMEALSA-DKGGFL--YLNRVLVILLQTLLQDE---------------------- 666
Query: 512 DADPTKSALSAVASLAAAWPQLHQGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKY 571
+A + +L G L + L ++SE++RL + S S +
Sbjct: 667 --------------IAEDYGEL--GMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDT 710
Query: 572 RYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTPGEKMKILHALCGKLLTLVSTR 631
D D A E ++KL ++ ++LT EK++IL ALC ++L S +
Sbjct: 711 D-------DNKDSAAFEDNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQ 763
Query: 632 DFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKE 691
D H + R++ +A + K + LKE+ K + +++K KE
Sbjct: 764 D-----------------------HMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKE 800
Query: 692 DEQRNST---ADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKR 748
E +N + +G+ +R+ E + + + TE ED + K R
Sbjct: 801 MEAKNKENGKVENGLGKTDRKK----------EIVKFEPQVDTEAEDMISAVKSRRLLAI 850
Query: 749 GQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEKIQSAIACTNIFPLGRD 808
+E +E + R+ EEE +++ EK E I A P+G D
Sbjct: 851 QAKKEREIQEREMKVKLERQA----EEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTD 906
Query: 809 RMYRRYWIFPS-IPGLFIEEDYSGLTEDMLLPRPSSF-QNNVQSQDPQVSTKTGEPLMSE 866
R + RYW+F +PGLFIE+ G D + R + +++ S D ++ + + +
Sbjct: 907 RNHNRYWLFSDEVPGLFIEK---GWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGK 963
Query: 867 STS-NIDQGPRDH-SVQLPKPVHKPNRWCFYSSCEQLDQLIEALNSRGHRESALKETLLQ 924
+ S N G +V+ P N W S ++LD+L+ L+ +G RES LKE L +
Sbjct: 964 NASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEK 1023
Query: 925 EKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRSSNAYDPSQMCAEKQLELRLRDFLL 984
I + H + KP K + D +Q +L LR L+
Sbjct: 1024 RYQDIIHSI--------HLARKPNLGLK----------SCDGNQ-----ELLNFLRSDLI 1060
Query: 985 DIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQT 1044
++ R+ +G LG ++ T R ++S E + D E I Q
Sbjct: 1061 EVATRLQKGGLGYVEETSEFEAR---------VISLEKLK---------DFGECVIALQA 1102
Query: 1045 KVIVK--DRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDA 1102
VI K + K + S +++ + V E++ ++ A
Sbjct: 1103 SVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDE----------------EKKMVEEAKVA 1146
Query: 1103 SDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWSKSILNARCKICRKKGDAEN 1162
S L++W+ ++ + + S++ + L LD + W S NARCK+CRKKG+ +
Sbjct: 1147 S--------ALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDK 1198
Query: 1163 MVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSM 1222
++LCD C++ H +C+RP L VP+G+W CP C+P R R + ED ED
Sbjct: 1199 LILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDE 1258
Query: 1223 GGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSF 1282
E++E EEE + EEE+YEV L R R + RGK S
Sbjct: 1259 SDEEEE----EEEEEEEEEDYEV------------AGLRLRPRKTI------RGKHSVIP 1296
Query: 1283 SSRGQQQEPGRYPSRSQQSTPK 1304
+ + PG+ P +++S PK
Sbjct: 1297 PAARSGRRPGKKPHSTRRSQPK 1318
Score = 60.1 bits (144), Expect = 2e-08
Identities = 30/91 (32%), Positives = 54/91 (59%), Gaps = 2/91 (2%)
Query: 1423 RRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREK 1482
+RSS RQ EL E+++ ++V++ SWPF + V++ + DYYD+I P+ ++ K
Sbjct: 1335 KRSSRRQS--LELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNK 1392
Query: 1483 VNKCEYKLASEFIDDIELMFSNCFEYNPRNT 1513
+ Y+ EF+ D++ +F+N YN R +
Sbjct: 1393 CSCGSYRSVQEFLTDMKQVFTNAEVYNCRGS 1423
Score = 57.0 bits (136), Expect = 1e-07
Identities = 48/188 (25%), Positives = 86/188 (45%), Gaps = 15/188 (7%)
Query: 2 PLLHRKPFVRQKPPADLRPDEEVFYCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRPG 61
PLL RKPF KP L +E +F T E FR +++ R + +W+C TG
Sbjct: 3 PLLGRKPFPLVKP---LPGEEPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQ 59
Query: 62 LTYQEALESEKKARQNL-QSFP---EPLIIPVLYLTSLTHRSRLHEICDDIFAYVKDRYF 117
LT++EA E E++ + L + FP E L++ +++ + + L ++ D + + +Y
Sbjct: 60 LTHKEAWEEEQEVAELLKEEFPAWYEKLVLEMVH----HNTASLEKLVDTAWLEIMTKYA 115
Query: 118 VEETVEVIRNNGARLQCRILEVLPPSHQNGFANGHVNSVDGETIIISDSDDSETQSCSFQ 177
V E + L+ +I+++ P + + S S D E S Q
Sbjct: 116 VGEECDFEVGKEKMLKVKIVKIHPLEK----VDEEATEKKSDGACDSPSSDKENSSQIAQ 171
Query: 178 NGKKKDAI 185
+ +KK+ +
Sbjct: 172 DHQKKETV 179
Score = 39.7 bits (91), Expect = 0.023
Identities = 41/186 (22%), Positives = 74/186 (39%), Gaps = 18/186 (9%)
Query: 1193 PECRPKQRSRR----LSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQD 1248
P+ +P ++S+ LSS P L ++ S+ G +V + EE E+ +
Sbjct: 313 PDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKM 372
Query: 1249 EDDSQEEEEVSLPKRGRPQVR------LPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQST 1302
++ +PK+G P + P+K +G+ S GQ+ + T
Sbjct: 373 MSPNKLHTNFHIPKKGPPAKKPGKHSDKPLKAKGR--SKGILNGQKSTGNSKSPKKGLKT 430
Query: 1303 PKTTVSSKT----GRSLRKINSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKR 1358
PKT + T + +K+ AP + R +S+ H H P A + + R
Sbjct: 431 PKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSKP--HKHLPPAALHLIAYYKENKDR 488
Query: 1359 RGRKSA 1364
++SA
Sbjct: 489 EDKRSA 494
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 116 bits (290), Expect = 2e-25
Identities = 109/428 (25%), Positives = 172/428 (40%), Gaps = 90/428 (21%)
Query: 853 PQVSTKTGEPLM-----SESTSNIDQGPRDHSVQLPKPVHKPNRWCFYSSCEQLDQLIEA 907
PQ T G+P S+ ++Q P P + W + E LD +++A
Sbjct: 1395 PQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWWWIRDPEMLDAMLKA 1454
Query: 908 LNSRGHRESALKETLLQEKSRICAQLARFSEEKFHFSDKPQPDSKPTYSRGRSSNAYDPS 967
L+ RG RE AL + L + + + R S + +P P + G S + P
Sbjct: 1455 LHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIF-----EPRQLPAFQEGIMS--WSPK 1507
Query: 968 QMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGI 1027
+ E +L + ++ ++E R+ L R + +S R +L E+
Sbjct: 1508 EKTYET--DLAVLQWVEELEQRVIMSDLQI-----RGWTCPSPDSTREDLAYCEHLS--- 1557
Query: 1028 IKTVNEDVEEMEIDEQTKVIVKDRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALFQI 1087
D Q + + R G + P +TN + M L +
Sbjct: 1558 -------------DSQEDITWRGR--GREGLAPQRKTTNP---------LDLAVMRLAAL 1593
Query: 1088 EQGIERRFLKAPL--------------------DASDSGRSYKTV--LDRWRESLLSSAS 1125
EQ +ERR+L+ PL + + + SY+ + WR++L S
Sbjct: 1594 EQNVERRYLREPLWPTHEVVLEKALLSTPNGAPEGTTTEISYEITPRIRVWRQTLERCRS 1653
Query: 1126 LSQVFLHLSTLDRSVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTV 1185
+QV L L L+RS+ W KS+ C +CRK + E ++LCDGCDRG H YC RPK++ V
Sbjct: 1654 AAQVCLCLGQLERSIAWEKSVNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAV 1713
Query: 1186 PEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEV 1245
PEGDWFC C +Q + GE + G + GQ + Y +
Sbjct: 1714 PEGDWFCTVCLAQQ----------------------VEGEFTQKPGFPKRGQKRKSGYSL 1751
Query: 1246 EQDEDDSQ 1253
E D +
Sbjct: 1752 NFSEGDGR 1759
Score = 85.1 bits (209), Expect = 5e-16
Identities = 70/231 (30%), Positives = 116/231 (50%), Gaps = 15/231 (6%)
Query: 264 PPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFE 323
P I N+ RP K++ + N +K +A + K ++ + Q ++ A
Sbjct: 677 PKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQKVQRGECQTTIQGQARN 736
Query: 324 KAKLKREKADALEAKKKEKEDKEK---KREELKKIVEEERLKKKEEKERLKVEREKER-- 378
K K + + EAKKK K +KEK K+E+LK+ V+ E+ +K + KE+ +V + K
Sbjct: 737 KRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKVKMKEKEEVTKAKPACK 796
Query: 379 -------EKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVK-TRLPPEIFGDALM 430
++ EE+++ L++ KP EDM D + LP+ + V LP F D L
Sbjct: 797 ADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSRVPGLTLPSGAFSDCLT 856
Query: 431 VLEFLNAFGELFDLQDEFPDGVTLEVLEEALV-GNDSEGPLCELLFFFLTA 480
++EFL++FG++ D D +L VL+E L+ DS G + +LL L A
Sbjct: 857 IVEFLHSFGKVLGF-DPAKDVPSLGVLQEGLLCQGDSLGEVQDLLVRLLKA 906
Score = 66.6 bits (161), Expect = 2e-10
Identities = 43/140 (30%), Positives = 70/140 (50%), Gaps = 10/140 (7%)
Query: 1397 LSLQESESKRR---CRKRQSPEPSP-------VTLGRRSSGRQGGVHELSAFEQLVVELV 1446
L+ E + +RR R R+SP P RR + +L+ E +++E+
Sbjct: 1751 LNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMRNHHSDLTFCEIILMEME 1810
Query: 1447 RHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCF 1506
HD +WPFL+ V+ V Y IIK P+ + +RE++ + Y + EF D L+F NC
Sbjct: 1811 SHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQ 1870
Query: 1507 EYNPRNTSEAKAGTRLQAFF 1526
+N ++ KAG ++ FF
Sbjct: 1871 TFNEDDSEVGKAGHIMRRFF 1890
Score = 39.7 bits (91), Expect = 0.023
Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 13/112 (11%)
Query: 729 MVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKE 788
M E+E++ + GRRG+R +G + T + P + E L + K+
Sbjct: 1053 MEEEEEEESIAAVPGRRGRR--DGEVDAT-------ASSIPELERQIEKLSKRQLFFRKK 1103
Query: 789 LLEKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDYSGLTEDMLLPR 840
LL Q A + LG+DR RRYW+ P + G+F+E L + ++ +
Sbjct: 1104 LLHSSQMLRAVS----LGQDRYRRRYWVLPYLAGIFVEGTEGNLVPEEVIKK 1151
Score = 37.7 bits (86), Expect = 0.087
Identities = 22/94 (23%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 651 LKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEERE- 709
++ + K ++E + +K ++K K +++K K KQEKLKE +R + + E+E
Sbjct: 730 IQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKVKMKEKEEVT 789
Query: 710 ------DFDTSIESKDTEQKELDQDMVTEDEDDP 737
D ++ ++ ++ Q M+ E+ P
Sbjct: 790 KAKPACKADKTLATQRRLEERQRQQMILEEMKKP 823
Score = 37.7 bits (86), Expect = 0.087
Identities = 27/94 (28%), Positives = 49/94 (52%), Gaps = 6/94 (6%)
Query: 645 KQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNST-----A 699
KQE + LK ++ K++ +A K K+EKLKE+ ++ K+++ K+KE E+ A
Sbjct: 739 KQETKSLK-QKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKVKMKEKEEVTKAKPACKA 797
Query: 700 DISIGEEEREDFDTSIESKDTEQKELDQDMVTED 733
D ++ + R + + E K+ +DM D
Sbjct: 798 DKTLATQRRLEERQRQQMILEEMKKPTEDMCLTD 831
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 110 bits (276), Expect = 8e-24
Identities = 54/148 (36%), Positives = 83/148 (56%), Gaps = 5/148 (3%)
Query: 1116 WRESLLSSASLSQVFLHLSTLDRSVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHT 1175
WR +L + S +QV L + L +S+ W KSI+ C+ICRK + E ++LCDGCD+G HT
Sbjct: 1899 WRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHT 1958
Query: 1176 YCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEE 1235
YC RPK+ T+P+GDWFCP C K + L ++ + +S G+ + GD E+
Sbjct: 1959 YCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLH--VKGKKTNESKKGKKVTLTGDTED 2016
Query: 1236 GQSEEEEYEVEQDEDDSQE---EEEVSL 1260
S +++ D ++ EE S+
Sbjct: 2017 EDSASTSSSLKRGNKDLKKRKMEENTSI 2044
Score = 85.9 bits (211), Expect = 3e-16
Identities = 74/223 (33%), Positives = 112/223 (50%), Gaps = 42/223 (18%)
Query: 297 LASYRSKATKERDKLLKQEEM---------------KSLAFEKAKLKREKADA--LEAKK 339
+A+ + KE+ K++KQ+E + + K K K E A+A LEA+K
Sbjct: 926 MAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEK 985
Query: 340 KEKE--------------DKEKKREELKKIVEEERLKKKEEKERLKVEREKE----REKL 381
+ KE ++E++R+ + + E KK EEKERLK E+ E +E+
Sbjct: 986 RIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERK 1045
Query: 382 REEKRKYVEYLKQWSKPREDMECDDLKELPE-PTPVKTRLPPEIFGDALMVLEFLNAFGE 440
E++R +E K+ KP EDM D K LPE P L F D LMV++FL FG+
Sbjct: 1046 LEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGSTFSDCLMVVQFLRNFGK 1105
Query: 441 L--FDLQDEFPDGVTLEVLEEALVG-NDSEGPLCELLFFFLTA 480
+ FD+ + P+ L VL+E L+ DS G + +LL L+A
Sbjct: 1106 VLGFDVNIDVPN---LSVLQEGLLNIGDSMGEVQDLLVRLLSA 1145
Score = 73.9 bits (180), Expect = 1e-12
Identities = 43/155 (27%), Positives = 78/155 (50%), Gaps = 10/155 (6%)
Query: 1378 RVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSS------GRQGG 1431
+V T +E S + +S L + K KR+ E + + L ++ S ++
Sbjct: 2007 KVTLTGDTEDEDSASTSSSLKRGNKDLK----KRKMEENTSINLSKQESFTSVKKPKRDD 2062
Query: 1432 VHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLA 1491
+L+ ++ E+ H+D+WPFL V+ VP Y +IKKP+ + IREK++ +Y
Sbjct: 2063 SKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNL 2122
Query: 1492 SEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFF 1526
F D+ L+F NC +N ++ +AG ++ +F
Sbjct: 2123 ETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYF 2157
Score = 45.4 bits (106), Expect = 4e-04
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 8/126 (6%)
Query: 1213 ESDEDVEDSMGGEDDEVDGDEEEGQSEEE---EYEVEQDEDDSQEEEEVSLPKRGRPQVR 1269
E D++ ED EDDE D + E S E E E+D+DD ++E S + + ++
Sbjct: 612 EEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMK 671
Query: 1270 LPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSK-----TGRSLRKINSAPPT 1324
L T S S S G + +++ S P S G S + S+P +
Sbjct: 672 LNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHS 731
Query: 1325 ETKSLR 1330
T R
Sbjct: 732 GTSKRR 737
Score = 36.6 bits (83), Expect = 0.19
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 23/116 (19%)
Query: 1214 SDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVK 1273
+D D+ S ED D +E++ + +EE+ E + + DDSQ E +
Sbjct: 594 TDSDIPSSKDSEDSNEDEEEDDEEEDEEDDE-DDESDDSQSESD---------------- 636
Query: 1274 TRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTETKSL 1329
+S + G ++E + Q + T KT L K S+ + + SL
Sbjct: 637 ----SNSESDTEGSEEEDD--DDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSL 686
Score = 36.6 bits (83), Expect = 0.19
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 1200 RSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDD---SQEEE 1256
R RR + D+D D G EDDE + D+E+ + ++ + ++DE D S EE
Sbjct: 1288 RKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEEL 1347
Query: 1257 EVSLPKRGRPQ 1267
E + K + Q
Sbjct: 1348 EKQIEKLSKQQ 1358
Score = 33.5 bits (75), Expect = 1.6
Identities = 40/155 (25%), Positives = 75/155 (48%), Gaps = 18/155 (11%)
Query: 638 VDILRQA-KQEFRELKAEQHRKEREEAAARIRKRKEE-KLKEQEQKMKEKQEKLKEDEQR 695
+ +LR+ KQE + E +++ AA RK+KE+ K+ +Q++K+K Q+ E E R
Sbjct: 901 IKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELR 960
Query: 696 NSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKE 755
I ++++++ + + + E++ +++M + +R RR
Sbjct: 961 --AQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERR---------- 1008
Query: 756 FTRQEQINCVTREP-LTADEEEALKQEHQRKEKEL 789
RQ + E A+E+E LKQE +R EK L
Sbjct: 1009 --RQHMMLMKAMEARKKAEEKERLKQE-KRDEKRL 1040
Score = 32.7 bits (73), Expect = 2.8
Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 1201 SRRLSSRQRPSLESDEDVEDSMGGEDDEVDGD-EEEGQSEEEEYEVEQDEDDSQEEEEVS 1259
S +SS LE DE+ ED E ++ D D E E Q + + D + + + +
Sbjct: 257 SEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKA 316
Query: 1260 LPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEP 1291
K ++ P+ + S + S + QQ++P
Sbjct: 317 TEKAQEKRIHQPLPLASE-SQTHSFQSQQKQP 347
Score = 32.0 bits (71), Expect = 4.8
Identities = 17/60 (28%), Positives = 26/60 (43%)
Query: 1198 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEE 1257
K R + + S +S + S G D EE + EE++ E ++DDS E E
Sbjct: 233 KPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESE 292
Score = 31.6 bits (70), Expect = 6.2
Identities = 27/116 (23%), Positives = 61/116 (52%), Gaps = 19/116 (16%)
Query: 635 EDYVDILRQAKQEFRELKAEQ----HRKEREEAA-ARI----RKRKEEKLKEQEQKMKEK 685
++ + ++Q + E +EL+A+Q +K++EEAA A++ ++ KE++++ Q+ + +
Sbjct: 944 QEKIKRIQQIRME-KELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKH 1002
Query: 686 QEK---------LKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTE 732
QE+ +K E R + ++E+ D + + EQ+ L+ +M E
Sbjct: 1003 QERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKE 1058
Score = 31.2 bits (69), Expect = 8.2
Identities = 28/137 (20%), Positives = 58/137 (42%), Gaps = 14/137 (10%)
Query: 671 KEEKLKEQEQKMKEKQEKLKEDEQR-NSTADISIGEEEREDFDTSIESKDTEQ--KELDQ 727
K + L + K+K+K+ + K E NS +D + + +S +S D E+ +E DQ
Sbjct: 218 KNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQ 277
Query: 728 DMVTEDEDDPGSHKRGRRGKRGQ-----------NGFKEFTRQEQINCVTREPLTADEEE 776
+ ++DD S + Q +G K + ++ PL ++ +
Sbjct: 278 SIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQT 337
Query: 777 ALKQEHQRKEKELLEKI 793
Q Q++ + L +++
Sbjct: 338 HSFQSQQKQPQVLSQQL 354
>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
sapiens]
Length = 837
Score = 73.9 bits (180), Expect = 1e-12
Identities = 30/100 (30%), Positives = 59/100 (59%)
Query: 1436 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1495
+ + L+ ++ H +WPF++ V K + PDYY++I+ PI L + E++ Y F+
Sbjct: 735 TTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFV 794
Query: 1496 DDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGL 1535
D++ + +NC EYNP ++ + + L+ FF+ + ++ GL
Sbjct: 795 ADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGL 834
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 73.6 bits (179), Expect = 1e-12
Identities = 65/228 (28%), Positives = 100/228 (43%), Gaps = 16/228 (7%)
Query: 1338 HSHGP-LQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASK 1396
HS GP L A P K++G K +T +P I S S ++ K
Sbjct: 255 HSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPT-----AILAPGSPASPPGSLEPK 309
Query: 1397 LSLQESESKRRCRKRQSPEPS-PVTLGRRSSGRQGGVHE-LSAFEQLVVELVRHDDS--- 1451
+ + R + P P + + S ++G + E L ++ EL+ +
Sbjct: 310 AARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYA 369
Query: 1452 WPFLKLV--SKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
WPF K V S + + DY+DIIK P+ L+ ++ K+ +Y+ A EF D+ LMFSNC++YN
Sbjct: 370 WPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYN 429
Query: 1510 PRNTSEAKAGTRLQAFFHIQAQKL---GLHVTPSNVDQVSTPPAAKKS 1554
P + +LQ F + K+ L P V P AK S
Sbjct: 430 PPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSS 477
Score = 57.4 bits (137), Expect = 1e-07
Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 5/97 (5%)
Query: 1416 PSPVTLGRRSSGRQGGVHELSAFEQLVVE-LVRHDDSWPFLKLVS--KIQVPDYYDIIKK 1472
P P + GR ++L ++V++ L +H +WPF + V K+ +PDY+ IIK+
Sbjct: 62 PPPEVSNPKKPGRV--TNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQ 119
Query: 1473 PIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
P+ + I+ ++ Y ASE + D MF+NC+ YN
Sbjct: 120 PMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
Score = 33.1 bits (74), Expect = 2.1
Identities = 33/140 (23%), Positives = 52/140 (37%), Gaps = 30/140 (21%)
Query: 1204 LSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEE------- 1256
+S+ P L E S E +EEE + EE+E E E + DS+EE
Sbjct: 465 VSTAMPPGLAKSSS-ESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAEL 523
Query: 1257 -----------------EVSLPKRGR-----PQVRLPVKTRGKLSSSFSSRGQQQEPGRY 1294
+S PKR R + R K RG+ + +G +
Sbjct: 524 QEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQ 583
Query: 1295 PSRSQQSTPKTTVSSKTGRS 1314
P +S++++ S+ G S
Sbjct: 584 PKKSKKASGSGGGSAALGPS 603
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 73.6 bits (179), Expect = 1e-12
Identities = 65/228 (28%), Positives = 100/228 (43%), Gaps = 16/228 (7%)
Query: 1338 HSHGP-LQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASK 1396
HS GP L A P K++G K +T +P I S S ++ K
Sbjct: 255 HSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPT-----AILAPGSPASPPGSLEPK 309
Query: 1397 LSLQESESKRRCRKRQSPEPS-PVTLGRRSSGRQGGVHE-LSAFEQLVVELVRHDDS--- 1451
+ + R + P P + + S ++G + E L ++ EL+ +
Sbjct: 310 AARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYA 369
Query: 1452 WPFLKLV--SKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
WPF K V S + + DY+DIIK P+ L+ ++ K+ +Y+ A EF D+ LMFSNC++YN
Sbjct: 370 WPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYN 429
Query: 1510 PRNTSEAKAGTRLQAFFHIQAQKL---GLHVTPSNVDQVSTPPAAKKS 1554
P + +LQ F + K+ L P V P AK S
Sbjct: 430 PPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSS 477
Score = 57.4 bits (137), Expect = 1e-07
Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 5/97 (5%)
Query: 1416 PSPVTLGRRSSGRQGGVHELSAFEQLVVE-LVRHDDSWPFLKLVS--KIQVPDYYDIIKK 1472
P P + GR ++L ++V++ L +H +WPF + V K+ +PDY+ IIK+
Sbjct: 62 PPPEVSNPKKPGRV--TNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQ 119
Query: 1473 PIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
P+ + I+ ++ Y ASE + D MF+NC+ YN
Sbjct: 120 PMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
Score = 33.1 bits (74), Expect = 2.1
Identities = 33/140 (23%), Positives = 52/140 (37%), Gaps = 30/140 (21%)
Query: 1204 LSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEE------- 1256
+S+ P L E S E +EEE + EE+E E E + DS+EE
Sbjct: 465 VSTAMPPGLAKSSS-ESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAEL 523
Query: 1257 -----------------EVSLPKRGR-----PQVRLPVKTRGKLSSSFSSRGQQQEPGRY 1294
+S PKR R + R K RG+ + +G +
Sbjct: 524 QEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQ 583
Query: 1295 PSRSQQSTPKTTVSSKTGRS 1314
P +S++++ S+ G S
Sbjct: 584 PKKSKKASGSGGGSAALGPS 603
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 73.2 bits (178), Expect = 2e-12
Identities = 39/97 (40%), Positives = 60/97 (61%), Gaps = 5/97 (5%)
Query: 1416 PSPVTLGRRSSGRQGGVHELSAFEQLVV-ELVRHDDSWPFLKLVS--KIQVPDYYDIIKK 1472
P P + + +GR ++L +++V+ +L +H SWPF + V K+Q+PDYY IIK
Sbjct: 15 PPPEYINTKKNGRL--TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKN 72
Query: 1473 PIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
P+ LN I++++ Y ASE I+D MFSNC+ YN
Sbjct: 73 PMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYN 109
Score = 64.7 bits (156), Expect = 7e-10
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 1451 SWPFLKLV--SKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEY 1508
+WPF V + + + +YYD++K P+ L I+EK++ EYK A +F D+ LMF NC++Y
Sbjct: 292 AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKY 351
Query: 1509 NPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPS 1540
NP + LQ F K+ + S
Sbjct: 352 NPPDHEVVTMARMLQDVFETHFSKIPIEPVES 383
Score = 35.8 bits (81), Expect = 0.33
Identities = 27/124 (21%), Positives = 63/124 (50%), Gaps = 5/124 (4%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
+ N A+ + +S S+ + + QE++K++ + L + L KKKEK KE
Sbjct: 400 ENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLN-KKKEKSKKE 458
Query: 347 KKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDD 406
KK+E++ E R + E+++++ + +R + ++ K++++ + + M D+
Sbjct: 459 KKKEKVNNSNENPR----KMCEQMRLKEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDE 514
Query: 407 LKEL 410
++L
Sbjct: 515 KRQL 518
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 73.2 bits (178), Expect = 2e-12
Identities = 39/97 (40%), Positives = 60/97 (61%), Gaps = 5/97 (5%)
Query: 1416 PSPVTLGRRSSGRQGGVHELSAFEQLVV-ELVRHDDSWPFLKLVS--KIQVPDYYDIIKK 1472
P P + + +GR ++L +++V+ +L +H SWPF + V K+Q+PDYY IIK
Sbjct: 15 PPPEYINTKKNGRL--TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKN 72
Query: 1473 PIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
P+ LN I++++ Y ASE I+D MFSNC+ YN
Sbjct: 73 PMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYN 109
Score = 64.7 bits (156), Expect = 7e-10
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 1451 SWPFLKLV--SKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEY 1508
+WPF V + + + +YYD++K P+ L I+EK++ EYK A +F D+ LMF NC++Y
Sbjct: 292 AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKY 351
Query: 1509 NPRNTSEAKAGTRLQAFFHIQAQKLGLHVTPS 1540
NP + LQ F K+ + S
Sbjct: 352 NPPDHEVVTMARMLQDVFETHFSKIPIEPVES 383
Score = 35.8 bits (81), Expect = 0.33
Identities = 27/124 (21%), Positives = 63/124 (50%), Gaps = 5/124 (4%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
+ N A+ + +S S+ + + QE++K++ + L + L KKKEK KE
Sbjct: 400 ENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLN-KKKEKSKKE 458
Query: 347 KKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDD 406
KK+E++ E R + E+++++ + +R + ++ K++++ + + M D+
Sbjct: 459 KKKEKVNNSNENPR----KMCEQMRLKEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDE 514
Query: 407 LKEL 410
++L
Sbjct: 515 KRQL 518
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 70.9 bits (172), Expect = 9e-12
Identities = 73/294 (24%), Positives = 121/294 (41%), Gaps = 39/294 (13%)
Query: 1151 CKICRKKG-DAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQR 1209
C CR +G +A+NM+ CD CDRG H C P L +P+G W C CRPK++ R+L +
Sbjct: 272 CSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKA 331
Query: 1210 PSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVR 1269
++ +G + + ++ V DE P RG+
Sbjct: 332 AQIK--RRYAKPIG---------RPKNKLKQRLLSVTSDEGSMNAFTGRGSPGRGQKTKV 380
Query: 1270 LPVKTRGKLSS--SFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTETK 1327
+ G +S SSR +P R + ++ +T T +S+ T + +K TK
Sbjct: 381 CTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTK 440
Query: 1328 SLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQ 1387
S R S G + F + PR+K ++S + V+AT ++++
Sbjct: 441 FF-TPSPDGRRSRGEIID--FSKHYRPRKKVSQKQSCTS-----------HVLATGTTQK 486
Query: 1388 SR----SVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSSGRQGGVHELSA 1437
+ S+ + +S Q S++ SP P +SS Q V LS+
Sbjct: 487 LKPPPSSLPPPTPISGQSPSSQKSSTATSSPSP-------QSSSSQCSVPSLSS 533
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 23/104 (22%)
Query: 1225 EDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSS 1284
E++E + DEEE + EEEE E E++E++ +EEEE + P++ P K F
Sbjct: 1070 EEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPF-- 1127
Query: 1285 RGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTETKS 1328
+ K GR R+INS+ TET S
Sbjct: 1128 ---------------------VLKKKRGRKRRRINSSVTTETIS 1150
Score = 46.2 bits (108), Expect = 2e-04
Identities = 92/477 (19%), Positives = 180/477 (37%), Gaps = 77/477 (16%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
+E + + + + + ++K L E + + E+ +L ++ E +++E++++E
Sbjct: 1021 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE 1080
Query: 347 KKREELKKIVEEERLKKKEEKERLKVERE-----KEREKLREEKRKYVEYLKQWSKPRED 401
++ EE ++ EEE +++EE+E ++ K + + KR +V K+ K R
Sbjct: 1081 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI 1140
Query: 402 MECDDLKELPEPTPVKTRLPPEIFGDALMVLEFLNAFGELFDLQDEFPDGVTLEVLEEAL 461
+ + E T V E FD DE LE E
Sbjct: 1141 NSSVTTETISETTEV---------------------LNEPFDNSDEERPMPQLEPTCEIE 1179
Query: 462 VGNDSEGPLCELLFFFLTAIFQAIAEEE---------EEVAKEQLTDADTKDLTEALDED 512
V D P+ F + EEE + + + D D+ +L E ++
Sbjct: 1180 VEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMND-DSSNLKEGSKDN 1238
Query: 513 ADPTKSALSAVASLAAAWPQ-LHQGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKY 571
+P K WP+ +G S + + T + L L+
Sbjct: 1239 PEPLK--------CKQVWPKGTKRGLSKWRQNKERKTGFK-LNLYTPPETPMEPDEQVTV 1289
Query: 572 RYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTPGEKMKILHALCGKLLTLVSTR 631
QK T +P +++ + L P E+ + C + S
Sbjct: 1290 EEQKETSEGKTS--------PSPIRIEEEVKETGEALLPQEENR-REETCAPVSPNTSPG 1340
Query: 632 DFIEDYVDILR----QAKQEFRELKAEQHRKEREEAAARIRK--------RKEE----KL 675
+ ED D+++ + ++E E + E+ E EE + K KEE
Sbjct: 1341 EKPED--DLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTE 1398
Query: 676 KEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTE 732
KE ++ + +E+ +EDE+ + D +E+ D+ +ES + E++EL ++ E
Sbjct: 1399 KEDSARLDDHEEEEEEDEEPSHNEDHDADDED----DSHMESAEVEKEELPRESFKE 1451
Score = 42.0 bits (97), Expect = 0.005
Identities = 30/139 (21%), Positives = 67/139 (48%), Gaps = 10/139 (7%)
Query: 650 ELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEERE 709
++ E+ ++ E + R EE++KE + + ++E +E+ + + S GE+ +
Sbjct: 1286 QVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPED 1345
Query: 710 DFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREP 769
D E ++ E++E +++ E E++ G G ++ +G K ++E E
Sbjct: 1346 DLIKPEEEEEEEEEEEEEEEEEEGEEEEG----GGNVEKDPDGAKSQEKEEP------EI 1395
Query: 770 LTADEEEALKQEHQRKEKE 788
T E+ A +H+ +E+E
Sbjct: 1396 STEKEDSARLDDHEEEEEE 1414
Score = 38.1 bits (87), Expect = 0.067
Identities = 26/114 (22%), Positives = 51/114 (44%), Gaps = 14/114 (12%)
Query: 641 LRQAKQEFRELKAEQHRKEREEAAARIR--------------KRKEEKLKEQEQKMKEKQ 686
+ + +E E Q REE A + K +EE+ +E+E++ +E++
Sbjct: 1307 IEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEE 1366
Query: 687 EKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSH 740
E+ +E+E + G + +E + I ++ + LD E+ED+ SH
Sbjct: 1367 EEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSH 1420
Score = 37.7 bits (86), Expect = 0.087
Identities = 30/133 (22%), Positives = 58/133 (43%), Gaps = 7/133 (5%)
Query: 659 EREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESK 718
ER + ++ EE+ +E++++ +E++E+ +EDE+ EEE E+ + +I+S
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEE-------EEEEEEEEENIQSS 1109
Query: 719 DTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEAL 778
+ + KRGR+ +R + T E + +DEE +
Sbjct: 1110 PPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPM 1169
Query: 779 KQEHQRKEKELLE 791
Q E E+ E
Sbjct: 1170 PQLEPTCEIEVEE 1182
Score = 37.0 bits (84), Expect = 0.15
Identities = 40/185 (21%), Positives = 76/185 (41%), Gaps = 36/185 (19%)
Query: 652 KAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDF 711
K E +E +AR+ +EE+ +++E E + ED+ +A++ E RE F
Sbjct: 1390 KEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESF 1449
Query: 712 DTSIESKDT-----------------------------EQKEL--DQDMVTEDEDDPGSH 740
+E+++T E KEL D + V E +++P
Sbjct: 1450 KEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPG 1509
Query: 741 KRGRRGKRGQNGFKEF-TRQEQINCVTRE--PLTADEEEALKQEHQRKEKELLEKIQSAI 797
++ + K+ Q KE T ++ N T E T ++L QE ++ + ++
Sbjct: 1510 EQAQ--KQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQE 1567
Query: 798 ACTNI 802
AC ++
Sbjct: 1568 ACRSL 1572
Score = 36.6 bits (83), Expect = 0.19
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 12/86 (13%)
Query: 1197 PKQRSRR------LSSRQRPSLESDEDV----EDSMGGEDDEVDGDEEEGQSEEEEYEVE 1246
P++ +RR +S P + ++D+ E+ E++E + +EEEG+ EE VE
Sbjct: 1320 PQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE 1379
Query: 1247 QDED--DSQEEEEVSLPKRGRPQVRL 1270
+D D SQE+EE + RL
Sbjct: 1380 KDPDGAKSQEKEEPEISTEKEDSARL 1405
Score = 33.9 bits (76), Expect = 1.3
Identities = 36/172 (20%), Positives = 77/172 (44%), Gaps = 22/172 (12%)
Query: 279 PPKRIHISQEDNVANKQTLAS---YRSKATKERDKLLKQEEMKS------LAFEKAKLKR 329
P +++ + ++ + +T S + + + LL QEE + ++ + ++
Sbjct: 1283 PDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEK 1342
Query: 330 EKADALEAKKKEKEDKEKKREELKKIVEEERL----------KKKEEKERLKVEREKERE 379
+ D ++ +++E+E++E++ EE ++ EEE K +EKE ++ EKE +
Sbjct: 1343 PEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKE-D 1401
Query: 380 KLREEKRKYVEYLKQWSKPREDMECDDLKE--LPEPTPVKTRLPPEIFGDAL 429
R + + E + ED + DD + + K LP E F + L
Sbjct: 1402 SARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVL 1453
Score = 33.9 bits (76), Expect = 1.3
Identities = 18/66 (27%), Positives = 36/66 (54%), Gaps = 3/66 (4%)
Query: 1206 SRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDED---DSQEEEEVSLPK 1262
S+++ E + EDS +D E + +E+E S E+++ + ++D +S E E+ LP+
Sbjct: 1387 SQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPR 1446
Query: 1263 RGRPQV 1268
+V
Sbjct: 1447 ESFKEV 1452
Score = 32.7 bits (73), Expect = 2.8
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 19/68 (27%)
Query: 1213 ESDEDVEDSMGGEDDEVDGDEEEG------------QSEEEEYEVEQDEDDS-------Q 1253
E +E+ E+ E++E +G+EEEG E+EE E+ +++DS +
Sbjct: 1351 EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEE 1410
Query: 1254 EEEEVSLP 1261
EEEE P
Sbjct: 1411 EEEEDEEP 1418
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 70.9 bits (172), Expect = 9e-12
Identities = 33/87 (37%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 1442 VVELVR-HDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIEL 1500
V+++V+ H DSWPFL+ V + P+YY IIK P+ ++ + +K+N Y EF++D++
Sbjct: 446 VLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKT 505
Query: 1501 MFSNCFEYNPRNTSEAKAGTRLQAFFH 1527
MF NC +YN ++ K L+ FH
Sbjct: 506 MFRNCRKYNGESSEYTKMSDNLERCFH 532
Score = 35.8 bits (81), Expect = 0.33
Identities = 39/160 (24%), Positives = 68/160 (42%), Gaps = 46/160 (28%)
Query: 274 RRRGRPPKRIHISQEDNVANKQTLASYRSK------------------------------ 303
+RRGRPPKR + +E ++ KQ S S+
Sbjct: 199 KRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQGTWWLLCQTEEEWRQVTE 258
Query: 304 ATKERDKLLKQEEMKSLAFE---------KAKLKREKADALEAKKKEKED----KEKKRE 350
+ +ER L +++ K L+ + K KR + E + D K K+E
Sbjct: 259 SFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIKPVKQE 318
Query: 351 ELKKIVEEERLKKKEEKERLKV---EREKEREKLREEKRK 387
E + E+ K+KEE+E ++ ++KE+E++ +E+RK
Sbjct: 319 ETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERK 358
Score = 32.0 bits (71), Expect = 4.8
Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 9/64 (14%)
Query: 327 LKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKR 386
+K+E+ L +K+K +E++ ++ V+ KKE+++ LK ER++E EEK
Sbjct: 315 VKQEETPVLTRIEKQKRKEEEEERQILLAVQ-----KKEQEQMLKEERKRE----LEEKV 365
Query: 387 KYVE 390
K VE
Sbjct: 366 KAVE 369
Score = 31.2 bits (69), Expect = 8.2
Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 18/84 (21%)
Query: 630 TRDFIEDYVDILRQAKQEFRELKAEQH-------------RKEREEAAARIRKRKEEKLK 676
+ DF+ + +++ Q + + KAE H ++E RI K+K ++ +
Sbjct: 276 SEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEE 335
Query: 677 EQEQ-----KMKEKQEKLKEDEQR 695
E+ Q + KE+++ LKE+ +R
Sbjct: 336 EERQILLAVQKKEQEQMLKEERKR 359
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 68.6 bits (166), Expect = 5e-11
Identities = 67/331 (20%), Positives = 127/331 (38%), Gaps = 43/331 (12%)
Query: 1227 DEVDGDEEEG-QSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPV-KTRGKLSSSFSS 1284
D++D +E++ + + E VEQ + +L + + Q+R + K R L
Sbjct: 2563 DKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQI 2622
Query: 1285 RGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTETKSLRIASRSTRHSHGPLQ 1344
Q++ + ++ + ++ + APP H L
Sbjct: 2623 EVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLL 2682
Query: 1345 ADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESES 1404
+ + S +RKR K +++ + ++I+T S E + + ES
Sbjct: 2683 STPTLPAASQKRKREEEKDSSSKSKKK------KMISTTSKETKKDTKLYCICKTPYDES 2736
Query: 1405 KRR-----------------------------CRKRQSPEPSPVTLGRRSSGRQGGVHEL 1435
K C + QS E + L + G+
Sbjct: 2737 KFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGL--- 2793
Query: 1436 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1495
++++ L H +WPFL+ V PDYY +IK+P+ L + E+V + Y+ +EF+
Sbjct: 2794 ---KRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFV 2850
Query: 1496 DDIELMFSNCFEYNPRNTSEAKAGTRLQAFF 1526
D+ +F NC YNP ++ + L++FF
Sbjct: 2851 ADMTKIFDNCRYYNPSDSPFYQCAEVLESFF 2881
Score = 48.1 bits (113), Expect = 6e-05
Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 5/64 (7%)
Query: 1134 STLDRSVIWSKSIL--NARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWF 1191
+ + R + S+ ++ + C++C K GD ++ C+ C +H CV+P L+ VPE +W
Sbjct: 374 TNIAREELMSEGVIQYDDHCRVCHKLGD---LLCCETCSAVYHLECVKPPLEEVPEDEWQ 430
Query: 1192 CPEC 1195
C C
Sbjct: 431 CEVC 434
Score = 45.8 bits (107), Expect = 3e-04
Identities = 23/48 (47%), Positives = 32/48 (66%), Gaps = 2/48 (4%)
Query: 1213 ESDEDVEDSMGGEDDEVDGDEEEGQSEE--EEYEVEQDEDDSQEEEEV 1258
E +E+ ED + E++E DGD EE Q E EE E+E+D+DDS EE+
Sbjct: 132 EEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEM 179
Score = 39.3 bits (90), Expect = 0.030
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 9/68 (13%)
Query: 1213 ESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSL---------PKR 1263
E D D E++ EDDE D EE+ + E+E D+DD+ E S P R
Sbjct: 147 EEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGR 206
Query: 1264 GRPQVRLP 1271
+P+V P
Sbjct: 207 RKPRVHRP 214
Score = 35.4 bits (80), Expect = 0.43
Identities = 42/195 (21%), Positives = 74/195 (37%), Gaps = 26/195 (13%)
Query: 627 LVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEE--KLKEQEQKMKE 684
L R+ I ++DI + R EE IR +K + +K E+ K+
Sbjct: 520 LEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKD 579
Query: 685 KQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDP------G 738
K +E N + D E+ RE+F+ KD++ K D D ++P G
Sbjct: 580 K------NETENDSKD---AEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKG 630
Query: 739 SHKRGRRGKRGQNGFKEFTRQEQ----INCVTREPLTADEEE-----ALKQEHQRKEKEL 789
+ G N E T + + C++ P +++ E L Q+ + +
Sbjct: 631 NSVSANLGDNTTNATSEETSPSEGRSPVGCLSETPDSSNMAEKKVASELPQDVPEEPNKT 690
Query: 790 LEKIQSAIACTNIFP 804
E ++ T+I P
Sbjct: 691 CESSNTSATTTSIQP 705
Score = 32.0 bits (71), Expect = 4.8
Identities = 42/202 (20%), Positives = 77/202 (38%), Gaps = 27/202 (13%)
Query: 1214 SDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDS----QEEEEVSLPKRGRPQVR 1269
++E++ +S+ + ++D + ++E+++ E E D D+ +E E+ SL K
Sbjct: 552 ANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEK------- 604
Query: 1270 LPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINS--APPTETK 1327
+ K +G+ +EP ++ +VS+ G + S P+E +
Sbjct: 605 ---DSDDKTPDDDPEQGKSEEP------TEVGDKGNSVSANLGDNTTNATSEETSPSEGR 655
Query: 1328 SLRIASRSTRHSHGPLQADVFVEL-----LSPRRKRRGRKSANNTPENSPNFPNFRVIAT 1382
S T S + V EL P + ++ T PN N +
Sbjct: 656 SPVGCLSETPDSSNMAEKKVASELPQDVPEEPNKTCESSNTSATTTSIQPNLENSNSSSE 715
Query: 1383 KSSEQSRSVNIASKLSLQESES 1404
+S QS S A E ES
Sbjct: 716 LNSSQSESAKAADDPENGERES 737
Score = 31.2 bits (69), Expect = 8.2
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 691 EDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDD 736
E E+ D+ EEE ED D E++D+E E +D + ED+DD
Sbjct: 130 ESEEEEEEEDMVSEEEEEEDGDAE-ETQDSEDDE--EDEMEEDDDD 172
Score = 31.2 bits (69), Expect = 8.2
Identities = 36/166 (21%), Positives = 76/166 (45%), Gaps = 16/166 (9%)
Query: 261 PDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDK----LLKQEE 316
P P T + P+ +G+P + + + N + L +S ER++ ++ +
Sbjct: 2502 PIQPHTSLQIPS---QGQPQSQPQVVMKHNAVIEH-LKQKKSMTPAEREENQRMIVCNQV 2557
Query: 317 MKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREK 376
MK + K+ +E+ A + +K+E+ ++K+ ++ + K KE+L+ E K
Sbjct: 2558 MKYIL---DKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFK---HKEQLRAEILK 2611
Query: 377 EREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRLPP 422
+R L +K +E ++ + + + DL +L + T V PP
Sbjct: 2612 KRALL--DKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPP 2655
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 68.6 bits (166), Expect = 5e-11
Identities = 67/331 (20%), Positives = 127/331 (38%), Gaps = 43/331 (12%)
Query: 1227 DEVDGDEEEG-QSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPV-KTRGKLSSSFSS 1284
D++D +E++ + + E VEQ + +L + + Q+R + K R L
Sbjct: 2580 DKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQI 2639
Query: 1285 RGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTETKSLRIASRSTRHSHGPLQ 1344
Q++ + ++ + ++ + APP H L
Sbjct: 2640 EVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLL 2699
Query: 1345 ADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESES 1404
+ + S +RKR K +++ + ++I+T S E + + ES
Sbjct: 2700 STPTLPAASQKRKREEEKDSSSKSKKK------KMISTTSKETKKDTKLYCICKTPYDES 2753
Query: 1405 KRR-----------------------------CRKRQSPEPSPVTLGRRSSGRQGGVHEL 1435
K C + QS E + L + G+
Sbjct: 2754 KFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGL--- 2810
Query: 1436 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1495
++++ L H +WPFL+ V PDYY +IK+P+ L + E+V + Y+ +EF+
Sbjct: 2811 ---KRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFV 2867
Query: 1496 DDIELMFSNCFEYNPRNTSEAKAGTRLQAFF 1526
D+ +F NC YNP ++ + L++FF
Sbjct: 2868 ADMTKIFDNCRYYNPSDSPFYQCAEVLESFF 2898
Score = 48.1 bits (113), Expect = 6e-05
Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 5/64 (7%)
Query: 1134 STLDRSVIWSKSIL--NARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWF 1191
+ + R + S+ ++ + C++C K GD ++ C+ C +H CV+P L+ VPE +W
Sbjct: 374 TNIAREELMSEGVIQYDDHCRVCHKLGD---LLCCETCSAVYHLECVKPPLEEVPEDEWQ 430
Query: 1192 CPEC 1195
C C
Sbjct: 431 CEVC 434
Score = 45.8 bits (107), Expect = 3e-04
Identities = 23/48 (47%), Positives = 32/48 (66%), Gaps = 2/48 (4%)
Query: 1213 ESDEDVEDSMGGEDDEVDGDEEEGQSEE--EEYEVEQDEDDSQEEEEV 1258
E +E+ ED + E++E DGD EE Q E EE E+E+D+DDS EE+
Sbjct: 132 EEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEM 179
Score = 39.3 bits (90), Expect = 0.030
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 9/68 (13%)
Query: 1213 ESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSL---------PKR 1263
E D D E++ EDDE D EE+ + E+E D+DD+ E S P R
Sbjct: 147 EEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGR 206
Query: 1264 GRPQVRLP 1271
+P+V P
Sbjct: 207 RKPRVHRP 214
Score = 31.2 bits (69), Expect = 8.2
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 691 EDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDD 736
E E+ D+ EEE ED D E++D+E E +D + ED+DD
Sbjct: 130 ESEEEEEEEDMVSEEEEEEDGDAE-ETQDSEDDE--EDEMEEDDDD 172
Score = 31.2 bits (69), Expect = 8.2
Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 11/104 (10%)
Query: 627 LVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEE--KLKEQEQKMKE 684
L R+ I ++DI + R EE IR +K + +K E+ K+
Sbjct: 520 LEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKD 579
Query: 685 KQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQD 728
K +E N + D E+ RE+F+ KD++ K D D
Sbjct: 580 K------NETENDSKD---AEKNREEFEDQSLEKDSDDKTPDDD 614
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 68.2 bits (165), Expect = 6e-11
Identities = 29/100 (29%), Positives = 56/100 (56%)
Query: 1436 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1495
S + ++ ++ H +WPF++ V + + P YY++I+ P+ L + E++ Y F+
Sbjct: 730 STLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFM 789
Query: 1496 DDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGL 1535
D++ +F+NC EYNP + K L+ FF + ++ GL
Sbjct: 790 ADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGL 829
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 66.2 bits (160), Expect = 2e-10
Identities = 67/283 (23%), Positives = 128/283 (45%), Gaps = 44/283 (15%)
Query: 1266 PQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQST---------------PKTTVSSK 1310
P +LP + + L ++ S+ QQ+P RSQQST P T +S
Sbjct: 889 PTTQLPQQVQPSLPAAPSADQPQQQP-----RSQQSTAASVPTPTAPLLPPQPATPLSQP 943
Query: 1311 TGRSLRKINSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPEN 1370
++++ P T + + + + + ++ + +E+ P + A+ PE+
Sbjct: 944 AVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQP-------EPADTQPED 996
Query: 1371 --SPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEP--SPVTLGRRSS 1426
+ ++ +T++ E+S + K +E + + SP P S + +
Sbjct: 997 ISESKVEDCKMESTETEERSTELKTEIK---EEEDQPSTSATQSSPAPGQSKKKIFKPEE 1053
Query: 1427 GRQGGVHELSAFEQLVVELVRHD-DSWPFLKLVSK--IQVPDYYDIIKKPIALNIIREKV 1483
RQ + L A L R D +S PF + V + +PDY+DI+K P+ L+ I+ K+
Sbjct: 1054 LRQALMPTLEA-------LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKL 1106
Query: 1484 NKCEYKLASEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFF 1526
+ +Y+ +++DDI LMF+N + YN + + K ++L F
Sbjct: 1107 DTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVF 1149
Score = 32.0 bits (71), Expect = 4.8
Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 7/95 (7%)
Query: 613 KMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKE 672
K K L K+L + + DY DI +QA ++ R A++ + + E
Sbjct: 1459 KPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATED-RLTSAKELPYFEGDFWPNV---LE 1514
Query: 673 EKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEE 707
E +KE EQ E++E+ +E+ N + D++ G+ +
Sbjct: 1515 ESIKELEQ---EEEERKREENTSNESTDVTKGDSK 1546
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 66.2 bits (160), Expect = 2e-10
Identities = 26/64 (40%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Query: 1151 CKICRKKG-DAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQR 1209
C CR +G +A+NM+ CD CDRG H C P L +P+G W C CRP+++ R+L ++
Sbjct: 265 CSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICRPRKKGRKLLQKKA 324
Query: 1210 PSLE 1213
++
Sbjct: 325 AQIK 328
Score = 42.7 bits (99), Expect = 0.003
Identities = 127/624 (20%), Positives = 240/624 (38%), Gaps = 125/624 (20%)
Query: 235 QDGVIKIKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVA-N 293
Q+ ++I +++ EQD SY + + +P + R H S N +
Sbjct: 805 QERELEISVGKSVSHENKEQD-SYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPS 863
Query: 294 KQTLASYRSKATKER----DKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKR 349
++ +++ T+ER D L EE S E+ EK++A + + E E++
Sbjct: 864 RRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVAS 923
Query: 350 EE--------------LKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVE----Y 391
EE L + VE R + K+ E LK + E+L R+Y E
Sbjct: 924 EEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERL---PRRYSEGDRAV 980
Query: 392 LKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLE-FLNAFGELFDLQDEFPD 450
L+ +S+ E+ E EP ++ PP + L + FL+ + +
Sbjct: 981 LRGFSESSEEEE--------EPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSS 1032
Query: 451 GVT------LEVLEEALVGNDSEGPLCELLFFFLTAIFQAIAEEEEE------------- 491
VT EVL+E +DSE P+ L F+ EEEEE
Sbjct: 1033 VVTETISETTEVLDEPFEDSDSERPMPRL-----EPTFEIDEEEEEEDENELFPREYFRR 1087
Query: 492 VAKEQLTDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLKSLDLDSCTLSE 551
++ + + + ++ DE+ D L L + +K+ L+ T +
Sbjct: 1088 LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPV--SLLRKRDVKNSPLEPDTSTP 1145
Query: 552 ILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTPG 611
+ + G + K R ++ GF +LS + + + +
Sbjct: 1146 LKKKKGWPKGKSRKPIHWKKRPGRKPGF----------KLSREIMPVSTQACVIEPIVSI 1195
Query: 612 EKMKILHALCGKLLTLVSTRDFIEDYVDI-LRQAKQEFRELKAEQHRKER--EEAAARIR 668
K G+ + + + +E D+ L + ++E E++AE E EE AA
Sbjct: 1196 PK-------AGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSE 1248
Query: 669 ---------------KRKEEKLKEQEQK---------MKEKQEKLKE---DEQRNSTADI 701
+ KE +++E+E+K +E+Q++L+E +E+ ++ A+
Sbjct: 1249 VPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
Query: 702 SIGEEEREDFDTSIESKDTEQKELDQDMVTED-EDDPGSHKRGRRGKRGQNGFKEFTRQE 760
+ ++ D + + T++KEL++ ED +++PG Q F + Q+
Sbjct: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGV----------QESFLDANMQK 1358
Query: 761 QINCVTREPLTADEEEALKQEHQR 784
+RE + EE L E ++
Sbjct: 1359 -----SREKIKDKEETELDSEEEQ 1377
Score = 35.4 bits (80), Expect = 0.43
Identities = 50/239 (20%), Positives = 92/239 (38%), Gaps = 34/239 (14%)
Query: 1211 SLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDED---DSQEEEEVSLPKRGRPQ 1267
S+ S+E+ E++ +G+ EE Q +E E E+ + +++E++ S+ +P+
Sbjct: 784 SVVSEEE-------EEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPE 836
Query: 1268 VRLPVKTRGKLS------SSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSA 1321
V PV + +LS S + Q GR+ R + T + + L + +SA
Sbjct: 837 VMAPVSST-RLSKQVLPHDSLPANSQPSRRGRW-GRKNRKTQERFGDKDSKLLLEETSSA 894
Query: 1322 PPTETKSLRIASRSTRHSHGPLQADVFVELLSP----------RRKRRGRKSANNTPENS 1371
P + S +T+ + + + P RR G + + S
Sbjct: 895 PQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKS 954
Query: 1372 PNFPNFRV------IATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRR 1424
P R+ + + SE R+V S +E E R P + TL R+
Sbjct: 955 PEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRK 1013
Score = 35.4 bits (80), Expect = 0.43
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Query: 1206 SRQRPSLESDE-DVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRG 1264
S P E+ E +VE+ E+++ EE+ QSEEE+ E+E E + +EEE+ +
Sbjct: 1257 SSNSPETETKEPEVEE----EEEKPRVSEEQRQSEEEQQELE--EPEPEEEEDAAAETAQ 1310
Query: 1265 RPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPT 1324
+ G L S+ + +++P R + + ++ + + +S KI T
Sbjct: 1311 NDDHDADDEDDGHLEST-KKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEET 1369
Query: 1325 ETKS 1328
E S
Sbjct: 1370 ELDS 1373
Score = 33.9 bits (76), Expect = 1.3
Identities = 38/170 (22%), Positives = 68/170 (40%), Gaps = 15/170 (8%)
Query: 642 RQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADI 701
RQ+++E +EL E+ E EE AA + ++ + E + K KE E++ + D+
Sbjct: 1284 RQSEEEQQEL--EEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDV 1341
Query: 702 SIGEEEREDF-DTSIES-----KDTEQKELD-------QDMVTEDEDDPGSHKRGRRGKR 748
+E F D +++ KD E+ ELD D E GS
Sbjct: 1342 KEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSH 1401
Query: 749 GQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEKIQSAIA 798
+ E +E+I + T ++L QE + + + + +A
Sbjct: 1402 TKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLA 1451
Score = 33.5 bits (75), Expect = 1.6
Identities = 29/140 (20%), Positives = 64/140 (45%), Gaps = 10/140 (7%)
Query: 662 EAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEE-----REDFDTSIE 716
+A + + ++ E+ E ++ M +E+ +E+E + + GEEE + +
Sbjct: 1197 KAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPAD 1256
Query: 717 SKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEE 776
S ++ + E + V E+E+ P + R+ + Q +E +E+ + E D+ +
Sbjct: 1257 SSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAA-ETAQNDDHD 1315
Query: 777 ALKQE----HQRKEKELLEK 792
A ++ K+KEL E+
Sbjct: 1316 ADDEDDGHLESTKKKELEEQ 1335
Score = 32.0 bits (71), Expect = 4.8
Identities = 29/139 (20%), Positives = 63/139 (45%), Gaps = 14/139 (10%)
Query: 287 QEDNVANKQTLA-----SYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKE 341
+E++ A+ + A S S T+ ++ +++EE K E+ + E+ LE + E
Sbjct: 1240 EEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPE 1299
Query: 342 KED--KEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYL------- 392
+E+ + + ++E E ++ ++E + RE ++EE +L
Sbjct: 1300 EEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKS 1359
Query: 393 KQWSKPREDMECDDLKELP 411
++ K +E+ E D +E P
Sbjct: 1360 REKIKDKEETELDSEEEQP 1378
Score = 32.0 bits (71), Expect = 4.8
Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 14/87 (16%)
Query: 1186 PEGDWFCPECRPKQRSRRLSSRQR-----------PSLESDEDVEDSMGGEDDEVDGDEE 1234
PE + PE ++ R+S QR P E +ED DD DE+
Sbjct: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 1235 EGQSE---EEEYEVEQDEDDSQEEEEV 1258
+G E ++E E + +D +EE V
Sbjct: 1321 DGHLESTKKKELEEQPTREDVKEEPGV 1347
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 66.2 bits (160), Expect = 2e-10
Identities = 26/64 (40%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Query: 1151 CKICRKKG-DAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQR 1209
C CR +G +A+NM+ CD CDRG H C P L +P+G W C CRP+++ R+L ++
Sbjct: 265 CSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICRPRKKGRKLLQKKA 324
Query: 1210 PSLE 1213
++
Sbjct: 325 AQIK 328
Score = 42.7 bits (99), Expect = 0.003
Identities = 127/624 (20%), Positives = 240/624 (38%), Gaps = 125/624 (20%)
Query: 235 QDGVIKIKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVA-N 293
Q+ ++I +++ EQD SY + + +P + R H S N +
Sbjct: 805 QERELEISVGKSVSHENKEQD-SYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPS 863
Query: 294 KQTLASYRSKATKER----DKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKR 349
++ +++ T+ER D L EE S E+ EK++A + + E E++
Sbjct: 864 RRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVAS 923
Query: 350 EE--------------LKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVE----Y 391
EE L + VE R + K+ E LK + E+L R+Y E
Sbjct: 924 EEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERL---PRRYSEGDRAV 980
Query: 392 LKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLE-FLNAFGELFDLQDEFPD 450
L+ +S+ E+ E EP ++ PP + L + FL+ + +
Sbjct: 981 LRGFSESSEEEE--------EPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSS 1032
Query: 451 GVT------LEVLEEALVGNDSEGPLCELLFFFLTAIFQAIAEEEEE------------- 491
VT EVL+E +DSE P+ L F+ EEEEE
Sbjct: 1033 VVTETISETTEVLDEPFEDSDSERPMPRL-----EPTFEIDEEEEEEDENELFPREYFRR 1087
Query: 492 VAKEQLTDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLKSLDLDSCTLSE 551
++ + + + ++ DE+ D L L + +K+ L+ T +
Sbjct: 1088 LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPV--SLLRKRDVKNSPLEPDTSTP 1145
Query: 552 ILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTPG 611
+ + G + K R ++ GF +LS + + + +
Sbjct: 1146 LKKKKGWPKGKSRKPIHWKKRPGRKPGF----------KLSREIMPVSTQACVIEPIVSI 1195
Query: 612 EKMKILHALCGKLLTLVSTRDFIEDYVDI-LRQAKQEFRELKAEQHRKER--EEAAARIR 668
K G+ + + + +E D+ L + ++E E++AE E EE AA
Sbjct: 1196 PK-------AGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSE 1248
Query: 669 ---------------KRKEEKLKEQEQK---------MKEKQEKLKE---DEQRNSTADI 701
+ KE +++E+E+K +E+Q++L+E +E+ ++ A+
Sbjct: 1249 VPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
Query: 702 SIGEEEREDFDTSIESKDTEQKELDQDMVTED-EDDPGSHKRGRRGKRGQNGFKEFTRQE 760
+ ++ D + + T++KEL++ ED +++PG Q F + Q+
Sbjct: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGV----------QESFLDANMQK 1358
Query: 761 QINCVTREPLTADEEEALKQEHQR 784
+RE + EE L E ++
Sbjct: 1359 -----SREKIKDKEETELDSEEEQ 1377
Score = 35.4 bits (80), Expect = 0.43
Identities = 50/239 (20%), Positives = 92/239 (38%), Gaps = 34/239 (14%)
Query: 1211 SLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDED---DSQEEEEVSLPKRGRPQ 1267
S+ S+E+ E++ +G+ EE Q +E E E+ + +++E++ S+ +P+
Sbjct: 784 SVVSEEE-------EEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPE 836
Query: 1268 VRLPVKTRGKLS------SSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSA 1321
V PV + +LS S + Q GR+ R + T + + L + +SA
Sbjct: 837 VMAPVSST-RLSKQVLPHDSLPANSQPSRRGRW-GRKNRKTQERFGDKDSKLLLEETSSA 894
Query: 1322 PPTETKSLRIASRSTRHSHGPLQADVFVELLSP----------RRKRRGRKSANNTPENS 1371
P + S +T+ + + + P RR G + + S
Sbjct: 895 PQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKS 954
Query: 1372 PNFPNFRV------IATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRR 1424
P R+ + + SE R+V S +E E R P + TL R+
Sbjct: 955 PEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRK 1013
Score = 35.4 bits (80), Expect = 0.43
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Query: 1206 SRQRPSLESDE-DVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRG 1264
S P E+ E +VE+ E+++ EE+ QSEEE+ E+E E + +EEE+ +
Sbjct: 1257 SSNSPETETKEPEVEE----EEEKPRVSEEQRQSEEEQQELE--EPEPEEEEDAAAETAQ 1310
Query: 1265 RPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPT 1324
+ G L S+ + +++P R + + ++ + + +S KI T
Sbjct: 1311 NDDHDADDEDDGHLEST-KKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEET 1369
Query: 1325 ETKS 1328
E S
Sbjct: 1370 ELDS 1373
Score = 33.9 bits (76), Expect = 1.3
Identities = 38/170 (22%), Positives = 68/170 (40%), Gaps = 15/170 (8%)
Query: 642 RQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADI 701
RQ+++E +EL E+ E EE AA + ++ + E + K KE E++ + D+
Sbjct: 1284 RQSEEEQQEL--EEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDV 1341
Query: 702 SIGEEEREDF-DTSIES-----KDTEQKELD-------QDMVTEDEDDPGSHKRGRRGKR 748
+E F D +++ KD E+ ELD D E GS
Sbjct: 1342 KEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSH 1401
Query: 749 GQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEKIQSAIA 798
+ E +E+I + T ++L QE + + + + +A
Sbjct: 1402 TKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLA 1451
Score = 33.5 bits (75), Expect = 1.6
Identities = 29/140 (20%), Positives = 64/140 (45%), Gaps = 10/140 (7%)
Query: 662 EAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEE-----REDFDTSIE 716
+A + + ++ E+ E ++ M +E+ +E+E + + GEEE + +
Sbjct: 1197 KAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPAD 1256
Query: 717 SKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEE 776
S ++ + E + V E+E+ P + R+ + Q +E +E+ + E D+ +
Sbjct: 1257 SSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAA-ETAQNDDHD 1315
Query: 777 ALKQE----HQRKEKELLEK 792
A ++ K+KEL E+
Sbjct: 1316 ADDEDDGHLESTKKKELEEQ 1335
Score = 32.0 bits (71), Expect = 4.8
Identities = 29/139 (20%), Positives = 63/139 (45%), Gaps = 14/139 (10%)
Query: 287 QEDNVANKQTLA-----SYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKE 341
+E++ A+ + A S S T+ ++ +++EE K E+ + E+ LE + E
Sbjct: 1240 EEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPE 1299
Query: 342 KED--KEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYL------- 392
+E+ + + ++E E ++ ++E + RE ++EE +L
Sbjct: 1300 EEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKS 1359
Query: 393 KQWSKPREDMECDDLKELP 411
++ K +E+ E D +E P
Sbjct: 1360 REKIKDKEETELDSEEEQP 1378
Score = 32.0 bits (71), Expect = 4.8
Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 14/87 (16%)
Query: 1186 PEGDWFCPECRPKQRSRRLSSRQR-----------PSLESDEDVEDSMGGEDDEVDGDEE 1234
PE + PE ++ R+S QR P E +ED DD DE+
Sbjct: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 1235 EGQSE---EEEYEVEQDEDDSQEEEEV 1258
+G E ++E E + +D +EE V
Sbjct: 1321 DGHLESTKKKELEEQPTREDVKEEPGV 1347
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 66.2 bits (160), Expect = 2e-10
Identities = 26/64 (40%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Query: 1151 CKICRKKG-DAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQR 1209
C CR +G +A+NM+ CD CDRG H C P L +P+G W C CRP+++ R+L ++
Sbjct: 265 CSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICRPRKKGRKLLQKKA 324
Query: 1210 PSLE 1213
++
Sbjct: 325 AQIK 328
Score = 42.7 bits (99), Expect = 0.003
Identities = 127/624 (20%), Positives = 240/624 (38%), Gaps = 125/624 (20%)
Query: 235 QDGVIKIKASSLSTYKIAEQDFSYFFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVA-N 293
Q+ ++I +++ EQD SY + + +P + R H S N +
Sbjct: 805 QERELEISVGKSVSHENKEQD-SYSVESEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPS 863
Query: 294 KQTLASYRSKATKER----DKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKR 349
++ +++ T+ER D L EE S E+ EK++A + + E E++
Sbjct: 864 RRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVAS 923
Query: 350 EE--------------LKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVE----Y 391
EE L + VE R + K+ E LK + E+L R+Y E
Sbjct: 924 EEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERL---PRRYSEGDRAV 980
Query: 392 LKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLE-FLNAFGELFDLQDEFPD 450
L+ +S+ E+ E EP ++ PP + L + FL+ + +
Sbjct: 981 LRGFSESSEEEE--------EPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSS 1032
Query: 451 GVT------LEVLEEALVGNDSEGPLCELLFFFLTAIFQAIAEEEEE------------- 491
VT EVL+E +DSE P+ L F+ EEEEE
Sbjct: 1033 VVTETISETTEVLDEPFEDSDSERPMPRL-----EPTFEIDEEEEEEDENELFPREYFRR 1087
Query: 492 VAKEQLTDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLKSLDLDSCTLSE 551
++ + + + ++ DE+ D L L + +K+ L+ T +
Sbjct: 1088 LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPV--SLLRKRDVKNSPLEPDTSTP 1145
Query: 552 ILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLSSTSVYDLTPG 611
+ + G + K R ++ GF +LS + + + +
Sbjct: 1146 LKKKKGWPKGKSRKPIHWKKRPGRKPGF----------KLSREIMPVSTQACVIEPIVSI 1195
Query: 612 EKMKILHALCGKLLTLVSTRDFIEDYVDI-LRQAKQEFRELKAEQHRKER--EEAAARIR 668
K G+ + + + +E D+ L + ++E E++AE E EE AA
Sbjct: 1196 PK-------AGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSE 1248
Query: 669 ---------------KRKEEKLKEQEQK---------MKEKQEKLKE---DEQRNSTADI 701
+ KE +++E+E+K +E+Q++L+E +E+ ++ A+
Sbjct: 1249 VPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAET 1308
Query: 702 SIGEEEREDFDTSIESKDTEQKELDQDMVTED-EDDPGSHKRGRRGKRGQNGFKEFTRQE 760
+ ++ D + + T++KEL++ ED +++PG Q F + Q+
Sbjct: 1309 AQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGV----------QESFLDANMQK 1358
Query: 761 QINCVTREPLTADEEEALKQEHQR 784
+RE + EE L E ++
Sbjct: 1359 -----SREKIKDKEETELDSEEEQ 1377
Score = 35.4 bits (80), Expect = 0.43
Identities = 50/239 (20%), Positives = 92/239 (38%), Gaps = 34/239 (14%)
Query: 1211 SLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDED---DSQEEEEVSLPKRGRPQ 1267
S+ S+E+ E++ +G+ EE Q +E E E+ + +++E++ S+ +P+
Sbjct: 784 SVVSEEE-------EEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPE 836
Query: 1268 VRLPVKTRGKLS------SSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSA 1321
V PV + +LS S + Q GR+ R + T + + L + +SA
Sbjct: 837 VMAPVSST-RLSKQVLPHDSLPANSQPSRRGRW-GRKNRKTQERFGDKDSKLLLEETSSA 894
Query: 1322 PPTETKSLRIASRSTRHSHGPLQADVFVELLSP----------RRKRRGRKSANNTPENS 1371
P + S +T+ + + + P RR G + + S
Sbjct: 895 PQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKS 954
Query: 1372 PNFPNFRV------IATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRR 1424
P R+ + + SE R+V S +E E R P + TL R+
Sbjct: 955 PEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRK 1013
Score = 35.4 bits (80), Expect = 0.43
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Query: 1206 SRQRPSLESDE-DVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRG 1264
S P E+ E +VE+ E+++ EE+ QSEEE+ E+E E + +EEE+ +
Sbjct: 1257 SSNSPETETKEPEVEE----EEEKPRVSEEQRQSEEEQQELE--EPEPEEEEDAAAETAQ 1310
Query: 1265 RPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPT 1324
+ G L S+ + +++P R + + ++ + + +S KI T
Sbjct: 1311 NDDHDADDEDDGHLEST-KKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEET 1369
Query: 1325 ETKS 1328
E S
Sbjct: 1370 ELDS 1373
Score = 33.9 bits (76), Expect = 1.3
Identities = 38/170 (22%), Positives = 68/170 (40%), Gaps = 15/170 (8%)
Query: 642 RQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADI 701
RQ+++E +EL E+ E EE AA + ++ + E + K KE E++ + D+
Sbjct: 1284 RQSEEEQQEL--EEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDV 1341
Query: 702 SIGEEEREDF-DTSIES-----KDTEQKELD-------QDMVTEDEDDPGSHKRGRRGKR 748
+E F D +++ KD E+ ELD D E GS
Sbjct: 1342 KEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSH 1401
Query: 749 GQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEKIQSAIA 798
+ E +E+I + T ++L QE + + + + +A
Sbjct: 1402 TKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLA 1451
Score = 33.5 bits (75), Expect = 1.6
Identities = 29/140 (20%), Positives = 64/140 (45%), Gaps = 10/140 (7%)
Query: 662 EAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEE-----REDFDTSIE 716
+A + + ++ E+ E ++ M +E+ +E+E + + GEEE + +
Sbjct: 1197 KAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPAD 1256
Query: 717 SKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEE 776
S ++ + E + V E+E+ P + R+ + Q +E +E+ + E D+ +
Sbjct: 1257 SSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAA-ETAQNDDHD 1315
Query: 777 ALKQE----HQRKEKELLEK 792
A ++ K+KEL E+
Sbjct: 1316 ADDEDDGHLESTKKKELEEQ 1335
Score = 32.0 bits (71), Expect = 4.8
Identities = 29/139 (20%), Positives = 63/139 (45%), Gaps = 14/139 (10%)
Query: 287 QEDNVANKQTLA-----SYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKE 341
+E++ A+ + A S S T+ ++ +++EE K E+ + E+ LE + E
Sbjct: 1240 EEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPE 1299
Query: 342 KED--KEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYL------- 392
+E+ + + ++E E ++ ++E + RE ++EE +L
Sbjct: 1300 EEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKS 1359
Query: 393 KQWSKPREDMECDDLKELP 411
++ K +E+ E D +E P
Sbjct: 1360 REKIKDKEETELDSEEEQP 1378
Score = 32.0 bits (71), Expect = 4.8
Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 14/87 (16%)
Query: 1186 PEGDWFCPECRPKQRSRRLSSRQR-----------PSLESDEDVEDSMGGEDDEVDGDEE 1234
PE + PE ++ R+S QR P E +ED DD DE+
Sbjct: 1261 PETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 1235 EGQSE---EEEYEVEQDEDDSQEEEEV 1258
+G E ++E E + +D +EE V
Sbjct: 1321 DGHLESTKKKELEEQPTREDVKEEPGV 1347
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 66.2 bits (160), Expect = 2e-10
Identities = 32/85 (37%), Positives = 51/85 (60%), Gaps = 2/85 (2%)
Query: 1451 SWPFLKLVSK--IQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEY 1508
+WPF K V +++ DY+DIIK P+ L+ ++ K++ EY A F D+ LMFSNC++Y
Sbjct: 331 AWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKY 390
Query: 1509 NPRNTSEAKAGTRLQAFFHIQAQKL 1533
NP + +LQ F ++ K+
Sbjct: 391 NPPDHEVVAMARKLQDVFEMRFAKM 415
Score = 59.7 bits (143), Expect = 2e-08
Identities = 33/97 (34%), Positives = 54/97 (55%), Gaps = 5/97 (5%)
Query: 1416 PSPVTLGRRSSGRQGGVHELSAFEQLVVE-LVRHDDSWPFLKLVS--KIQVPDYYDIIKK 1472
P P GR+ ++L + +VV+ L +H +WPF + V K+ +PDY+ IIK
Sbjct: 22 PPPEVSNPSKPGRK--TNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKN 79
Query: 1473 PIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
P+ + I++++ Y ASE + D MF+NC+ YN
Sbjct: 80 PMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYN 116
Score = 42.7 bits (99), Expect = 0.003
Identities = 54/243 (22%), Positives = 109/243 (44%), Gaps = 27/243 (11%)
Query: 286 SQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDK 345
S E++ ++ + S +AT+ + QE++K++ + A L + + + KKKEK++K
Sbjct: 442 SSEESSSDSGSSDSEEERATRLAEL---QEQLKAVHEQLAALSQAPVNKPK-KKKEKKEK 497
Query: 346 EKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYL---KQWSKPREDM 402
EKK+++ +K E+ ++K +EEK+ K+ ++ + +K +Q K +
Sbjct: 498 EKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQA 557
Query: 403 ECD-DLKELPEPTPVK-----------TRLPPEIFGDALMVLEFLNAFGELFDLQDEFPD 450
D +E E P+ RLP E G + +++ L+D PD
Sbjct: 558 SASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREP-----SLRDSNPD 612
Query: 451 GVTL--EVLEEALVGNDSEGPLCELLFFFLTAIFQAIAEEEEEVAKEQLTDADTKDLTEA 508
+ + E L+ + + E + L F A +++ +KE+L K+L +
Sbjct: 613 EIEIDFETLKPTTL-RELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKR 671
Query: 509 LDE 511
L +
Sbjct: 672 LQD 674
Score = 35.8 bits (81), Expect = 0.33
Identities = 50/216 (23%), Positives = 89/216 (41%), Gaps = 20/216 (9%)
Query: 1233 EEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFS--SRGQQQE 1290
E++ + +E+E E + + + +++ +V+ P + Q + P K +++ +G +Q
Sbjct: 498 EKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQA 557
Query: 1291 PGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTE----TKSLRIASRSTRHSHGPLQAD 1346
Y S ++ + K SL IN P + ++ S R S+ P + +
Sbjct: 558 SASYDSEEEEEGLPMSYDEKRQLSL-DINRLPGEKLGRVVHIIQSREPSLRDSN-PDEIE 615
Query: 1347 VFVELLSP---RRKRRGRKSANNTPENSPNFPNFRVIATKSSE---QSRSVNIASKL--- 1397
+ E L P R R KS + P + + A KS E Q + + +L
Sbjct: 616 IDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDV 675
Query: 1398 SLQESESKRRCRKRQ---SPEPSPVTLGRRSSGRQG 1430
S Q S SK+ RK + +P P L SS G
Sbjct: 676 SGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESG 711
Score = 34.3 bits (77), Expect = 0.96
Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 16/142 (11%)
Query: 654 EQHRKEREEAAARIRK--RKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDF 711
EQ + E+ AA + K +K KE+++K K+K++K KE E+ A EE +
Sbjct: 468 EQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKA------EEEKKA 521
Query: 712 DTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLT 771
+ +K +QK+ K+G GK+ + +E + P++
Sbjct: 522 KVAPPAKQAQQKKAPAKKANSTTTAGRQLKKG--GKQASASYDSEEEEEGL------PMS 573
Query: 772 ADEEEALKQEHQRKEKELLEKI 793
DE+ L + R E L ++
Sbjct: 574 YDEKRQLSLDINRLPGEKLGRV 595
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 65.9 bits (159), Expect = 3e-10
Identities = 25/57 (43%), Positives = 35/57 (61%)
Query: 1151 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSR 1207
CK C E ++LCD CD G+HT C+RP L +P+G+WFCP C+ K +L +
Sbjct: 894 CKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQ 950
Score = 45.4 bits (106), Expect = 4e-04
Identities = 122/564 (21%), Positives = 215/564 (38%), Gaps = 94/564 (16%)
Query: 286 SQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREK----------ADAL 335
SQ+DN + + S + TK+ ++ KQEE K E K+K E+ A+ L
Sbjct: 218 SQQDNSSRESP--SLEDEETKKEEETPKQEEQK----ESEKMKSEEQPMDLENRSTANVL 271
Query: 336 EAK--KKEKEDKEK--------------KREELKKIVEEERLKKKEEKERLKVEREKERE 379
E KKEKED+++ E KKI++EE KE + +KVE ++ R
Sbjct: 272 EETTVKKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKEESDSFKENVKPIKVEVKECRA 331
Query: 380 KLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLEFLNAFG 439
++ K + + Q +P ++K E T T ++ D +
Sbjct: 332 DPKDTKSSMEKPVAQ--EPERIEFGGNIKSSHEITEKSTEETEKLKNDQQAKIPLKK--- 386
Query: 440 ELFDLQDEFPDGVTLEVLEEALVGNDSEGPLCELLFFFLTAIFQAIAEEEEEVAK----- 494
L D+F V +GPLC+ + + I +EEE +
Sbjct: 387 REIKLSDDFDSPV--------------KGPLCKSVTPTKEFLKDEIKQEEETCKRISTIT 432
Query: 495 ------EQLTDADTKDLTEALDEDADP--TKSALSAVASLAAAWPQ--LHQGCSLKSLD- 543
+QL + + D A + +P TK + S + + + + +G +SL+
Sbjct: 433 ALGHEGKQLVNGEVSDERVAPNFKTEPIETKFYETKEESYSPSKDRNIITEGNGTESLNS 492
Query: 544 -LDSCTLSEILR-LHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSNPSLVKKLS 601
+ S E+ + L AD +S + + ++ + D ME L + + K LS
Sbjct: 493 VITSMKTGELEKETAPLRKDAD-SSISVLEIHSQKAQIEEPDPPEMETSLDSSEMAKDLS 551
Query: 602 STSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKERE 661
S + T MK T R I + ++ L ++K+ F + A++ E
Sbjct: 552 SKTALSSTESCTMKGEEK---SPKTKKDKRPPILECLEKLEKSKKTFLDKDAQRLSPIPE 608
Query: 662 EAAARIRKRKEEKLKEQEQKMK--------EKQEKLKEDEQRNSTADISIGEEEREDFDT 713
E + ++ E + EK KE + ST+ + ++ D +T
Sbjct: 609 EVPKSTLESEKPGSPEAAETSPPSNIIDHCEKLASEKEVVECQSTSTVGGQSVKKVDLET 668
Query: 714 SIESKDTEQKELD--QDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLT 771
E + + E+D + T ++P K G ++ FK V E T
Sbjct: 669 LKEDSEFTKVEMDNLDNAQTSGIEEPSETK----GSMQKSKFK-------YKLVPEEETT 717
Query: 772 ADEEEALKQEHQRKEKELLEKIQS 795
A E + E Q++ +L +I S
Sbjct: 718 ASENTEITSERQKEGIKLTIRISS 741
Score = 36.2 bits (82), Expect = 0.25
Identities = 48/230 (20%), Positives = 87/230 (37%), Gaps = 37/230 (16%)
Query: 1201 SRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSL 1260
+RR R+ L+SD ++ +++E + + + ++E+ V + D EE+ S
Sbjct: 1083 ARRKKRRRLNDLDSDSNL------DEEESEDEFKISDGSQDEFVVSDENPDESEEDPPS- 1135
Query: 1261 PKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINS 1320
+ F SR ++ P R +S++ KT K
Sbjct: 1136 --------------NDDSDTDFCSRRLRRHPSRPMRQSRRLRRKTP----------KKKY 1171
Query: 1321 APPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVI 1380
+ E + SR + +D FVE RR RR +K N E+S +
Sbjct: 1172 SDDDEEEESEENSRDSESDFSDDFSDDFVE-TRRRRSRRNQKRQINYKEDSESDG----- 1225
Query: 1381 ATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSSGRQG 1430
+ KS + + + K L SES+ + S + +RS ++G
Sbjct: 1226 SQKSLRRGKEIRRVHKRRLSSSESEESYLSKNSEDDELAKESKRSVRKRG 1275
Score = 35.4 bits (80), Expect = 0.43
Identities = 52/233 (22%), Positives = 93/233 (39%), Gaps = 25/233 (10%)
Query: 154 NSVDGETIIISDSDDSETQSCSFQNGKKKDAIDPLLFKYKVQPTKKELHESAIVKATQI- 212
N +D + S+ + E QS S G+ +D K + TK E+ + + I
Sbjct: 633 NIIDHCEKLASEKEVVECQSTSTVGGQSVKKVDLETLKEDSEFTKVEMDNLDNAQTSGIE 692
Query: 213 --SRRKHLFSRDKLKLFLKQHCEPQDGVIKIKASSLSTYKIAEQDFSYFFPDDPPTFIFS 270
S K + K K L P++ + + +++ + E T S
Sbjct: 693 EPSETKGSMQKSKFKYKLV----PEEETTASENTEITSERQKE--------GIKLTIRIS 740
Query: 271 PANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKRE 330
++ PPK + NKQ + T L + + + A+++ +
Sbjct: 741 SRKKKPDSPPKVLEPE------NKQEKTEKEEEKTNVGRTLRRSPRISRPTAKVAEIRDQ 794
Query: 331 KADALEAKKKEKEDK-EKKREELKKIVEEERLKKKEEKERLKVEREKEREKLR 382
KAD K+ E ED+ E++ L+K ++E LKK E+ KV + K + K+R
Sbjct: 795 KADK---KRGEGEDEVEEESTALQKTDKKEILKKSEKDTNSKVSKVKPKGKVR 844
Score = 34.7 bits (78), Expect = 0.74
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 13/104 (12%)
Query: 647 EFRELKAEQHRKE-----REEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADI 701
E R+ KA++ R E EE+ A + K+E LK+ E+ K K+K + T
Sbjct: 790 EIRDQKADKKRGEGEDEVEEESTALQKTDKKEILKKSEKDTNSKVSKVKPKGKVRWTGSR 849
Query: 702 SIG--------EEEREDFDTSIESKDTEQKELDQDMVTEDEDDP 737
+ G E E + S + + E+++ ++ + D+D+P
Sbjct: 850 TRGRWKYSSNDESEGSGSEKSSAASEEEEEKESEEAILADDDEP 893
Score = 34.7 bits (78), Expect = 0.74
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 1187 EGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVE 1246
E D R + RR+ R+ S ES+E S EDDE+ + + + E
Sbjct: 1222 ESDGSQKSLRRGKEIRRVHKRRLSSSESEESYL-SKNSEDDELAKESKRSVRKRGRSTDE 1280
Query: 1247 QDEDDSQEEEEVSLPKRGR 1265
E D +EEEE P R R
Sbjct: 1281 YSEADEEEEEEEGKPSRKR 1299
Score = 33.5 bits (75), Expect = 1.6
Identities = 32/157 (20%), Positives = 71/157 (45%), Gaps = 22/157 (14%)
Query: 282 RIHISQEDN---------VANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKA 332
R++I ++D+ V N+ LA + + D +L + + + + +
Sbjct: 174 RMYIEEQDDQDGSSWKCIVRNRNELAETLALLKAQIDPVLLKNSSQQ---DNSSRESPSL 230
Query: 333 DALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVE-- 390
+ E KK+E+ K+++++E +K+ EE+ E + V E +K +E++++ V+
Sbjct: 231 EDEETKKEEETPKQEEQKESEKMKSEEQPMDLENRSTANVLEETTVKKEKEDEKELVKLP 290
Query: 391 YLKQWSKPRED--------MECDDLKELPEPTPVKTR 419
+ + KP + E D KE +P V+ +
Sbjct: 291 VIVKLEKPLPENEEKKIIKEESDSFKENVKPIKVEVK 327
Score = 32.3 bits (72), Expect = 3.7
Identities = 26/128 (20%), Positives = 52/128 (40%), Gaps = 13/128 (10%)
Query: 670 RKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDM 729
R+ +L+ + K K + +E+ + NS S ++ D + + + + Q
Sbjct: 1157 RQSRRLRRKTPKKKYSDDDEEEESEENSRDSESDFSDDFSDDFVETRRRRSRRNQKRQIN 1216
Query: 730 VTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKEL 789
ED + GS K RRGK +I V + L++ E E ++ EL
Sbjct: 1217 YKEDSESDGSQKSLRRGK-------------EIRRVHKRRLSSSESEESYLSKNSEDDEL 1263
Query: 790 LEKIQSAI 797
++ + ++
Sbjct: 1264 AKESKRSV 1271
Score = 31.6 bits (70), Expect = 6.2
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 14/118 (11%)
Query: 1205 SSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQ------------DEDDS 1252
SSR+ PSLE +E ++ + +E + E+ +SEE+ ++E ++
Sbjct: 223 SSRESPSLEDEETKKEEETPKQEE-QKESEKMKSEEQPMDLENRSTANVLEETTVKKEKE 281
Query: 1253 QEEEEVSLPKRGRPQVRLPVKTRGKLSSSFS-SRGQQQEPGRYPSRSQQSTPKTTVSS 1309
E+E V LP + + LP K+ S S + +P + + ++ PK T SS
Sbjct: 282 DEKELVKLPVIVKLEKPLPENEEKKIIKEESDSFKENVKPIKVEVKECRADPKDTKSS 339
Score = 31.2 bits (69), Expect = 8.2
Identities = 56/279 (20%), Positives = 102/279 (36%), Gaps = 26/279 (9%)
Query: 1196 RPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEE------------EEY 1243
RP ++SRRL + SD+D E+ + + D + S++ ++
Sbjct: 1154 RPMRQSRRLRRKTPKKKYSDDDEEEESEENSRDSESDFSDDFSDDFVETRRRRSRRNQKR 1213
Query: 1244 EVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSS----FSSRGQQQEPGRYPSRSQ 1299
++ ED + + SL +RG+ ++R K R S S S + E + RS
Sbjct: 1214 QINYKEDSESDGSQKSL-RRGK-EIRRVHKRRLSSSESEESYLSKNSEDDELAKESKRSV 1271
Query: 1300 QSTPKTTVSSKTGRSLRKINSAPPTETKSLRIAS---RSTRHSHGPLQ--ADVFVELLSP 1354
+ ++T + P+ + RI + S ++HG A + P
Sbjct: 1272 RKRGRSTDEYSEADEEEEEEEGKPSRKRLHRIETDEEESCDNAHGDANQPARDSQPRVLP 1331
Query: 1355 RRKRRGRKSANNTPENSPNFPNFRVIATK---SSEQSRSVNIASKLSLQESESKRRCRKR 1411
+ +K + +F N + + S S N S E+ + K
Sbjct: 1332 SEQESTKKPYRIESDEEEDFENVGKVGSPLDYSLVDLPSTNGQSPGKAIENLIGKPTEKS 1391
Query: 1412 QSPEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDD 1450
Q+P+ + +S G E A E+ EL+R D
Sbjct: 1392 QTPKDNSTASASLASNGTSGGQEAGAPEEEEDELLRVTD 1430
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 65.9 bits (159), Expect = 3e-10
Identities = 41/161 (25%), Positives = 87/161 (54%), Gaps = 8/161 (4%)
Query: 636 DYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRK----EEKLKEQEQKMKEKQEKLKE 691
D + + + QE + +Q K REE R R++K EE ++EQE+KM+E++EK++E
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 692 DEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQN 751
E++ + + E+E + ++ + + E+K +Q + E ++ H++ + ++ Q
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE 681
Query: 752 GFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEK 792
++ QE++ T+E E++ QE R+E+ + E+
Sbjct: 682 QEEKIWEQEKMEKKTQE----QEKKTWDQEKMREEESMRER 718
Score = 60.1 bits (144), Expect = 2e-08
Identities = 36/147 (24%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
Query: 642 RQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADI 701
++ K +E + + KE E +R++KE L+EQE++M+E++EK+ E E++ +
Sbjct: 312 QEEKMWRQEKRLREQEKELREQEKELREQKE--LREQEEQMQEQEEKMWEQEEKMREQEE 369
Query: 702 SIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQ 761
+ +E ++ + ++ EQK DQ+ ++D+ K R ++ + + +E+
Sbjct: 370 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE 429
Query: 762 INCVTREPLTADEEEALKQEHQRKEKE 788
+E T D+EE +++E + +E+E
Sbjct: 430 KKMQEQEKKTRDQEEKMQEEERIRERE 456
Score = 58.5 bits (140), Expect = 5e-08
Identities = 33/148 (22%), Positives = 80/148 (54%), Gaps = 1/148 (0%)
Query: 641 LRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTAD 700
LR+ ++E RE K + ++E+ + +EEK++EQE+KM ++E+L E E++ +
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389
Query: 701 ISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQE 760
+ ++E ++ ++ E++ +Q+ + E + K+ + ++ + +E QE
Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK-KTRDQEEKMQE 448
Query: 761 QINCVTREPLTADEEEALKQEHQRKEKE 788
+ RE +EEE ++++ ++ +K+
Sbjct: 449 EERIREREKKMREEEETMREQEEKMQKQ 476
Score = 55.5 bits (132), Expect = 4e-07
Identities = 45/159 (28%), Positives = 82/159 (51%), Gaps = 12/159 (7%)
Query: 646 QEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGE 705
QE E EQ K RE+ R+ EE+L EQE++M+E+++K+++ E+R D + E
Sbjct: 351 QEQEEKMWEQEEKMREQEEKMWRQ--EERLWEQEKQMREQEQKMRDQEERMWEQDERLRE 408
Query: 706 E-----EREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQE 760
+ E+E +E E+K +Q+ T D+++ + R + + +E T +E
Sbjct: 409 KEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMRE 468
Query: 761 QINCVTR--EPLTADEEEALKQEHQRKEKELL---EKIQ 794
Q + + E + EE+ +Q+ ++KE L EK+Q
Sbjct: 469 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Score = 54.7 bits (130), Expect = 7e-07
Identities = 44/155 (28%), Positives = 79/155 (50%), Gaps = 11/155 (7%)
Query: 651 LKAEQHRKERE--EAAARIRK------RKEEKLKEQEQKMKEKQEKLKEDEQRNSTADIS 702
L+ E R+E E E +IRK R+EE+L+EQE KM+E++EK+ E+R +
Sbjct: 270 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKE 329
Query: 703 IGEEEREDFDTSIESKDTEQKELDQDMVTEDEDD--PGSHKRGRRGKRGQNGFKEFTRQE 760
+ E+E+E + + EQ + ++ + E E+ K R+ +R K+ QE
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389
Query: 761 QINCVTREPL-TADEEEALKQEHQRKEKELLEKIQ 794
Q E + DE K+E R+++++ E+++
Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVE 424
Score = 52.8 bits (125), Expect = 3e-06
Identities = 41/172 (23%), Positives = 89/172 (51%), Gaps = 23/172 (13%)
Query: 641 LRQAKQEFRELKA--EQHRKEREEAAARIRKRK----------EEKLKEQEQKMKEKQEK 688
LR+ ++ RE + EQ K REE + +++K EE+++E+E+KM+E++E
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEET 465
Query: 689 LKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKE--LDQDMVTEDEDDPGSHKRGRR- 745
++E E++ + ++ E+E +++ + + EQKE +Q+ + E E+ + R
Sbjct: 466 MREQEEKMQKQEENMWEQEEKEWQ---QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 522
Query: 746 -----GKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEK 792
G+ + +E R+++ +E D+E+ + + +R EK+ E+
Sbjct: 523 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574
Score = 52.8 bits (125), Expect = 3e-06
Identities = 37/120 (30%), Positives = 67/120 (55%), Gaps = 8/120 (6%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDK- 345
QE+ + ++ + K +E + + +QEE EK + + EK E K +E+E+K
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640
Query: 346 ----EKKREELKKIVEEERLKKKEEKERL-KVEREKEREKLREEKRKYVEYLKQWSKPRE 400
EK E+ +K+ E++RL E+KE+L + E+ +E+EK++E++ K E K K +E
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLP--EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698
Score = 52.4 bits (124), Expect = 3e-06
Identities = 36/124 (29%), Positives = 71/124 (57%), Gaps = 4/124 (3%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
QE+ + ++ + K +E+++ ++ +E + +E+ + REK + + ++K E E
Sbjct: 367 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERM--WEQDERLREKEERMREQEKMWEQVE 424
Query: 347 KKREELKKIVEEERLKKKEEKERLKVEREKERE-KLREEKRKYVEYLKQWSKPREDMECD 405
K REE KK+ E+E+ + +E++ + ER +ERE K+REE+ E ++ K E+M
Sbjct: 425 KMREE-KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 483
Query: 406 DLKE 409
+ KE
Sbjct: 484 EEKE 487
Score = 52.0 bits (123), Expect = 4e-06
Identities = 31/139 (22%), Positives = 72/139 (51%), Gaps = 3/139 (2%)
Query: 645 KQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIG 704
+QE E K ++ K+ + + R+EE ++E+E+KM+E++E ++E E++ + +
Sbjct: 688 EQEKMEKKTQEQEKKTWDQE---KMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744
Query: 705 EEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINC 764
E+E E ++ + + E+K +Q + E ++ H++ + ++ ++ QE+
Sbjct: 745 EQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMR 804
Query: 765 VTREPLTADEEEALKQEHQ 783
E + EE+ QE +
Sbjct: 805 GQEEKMRGQEEKMRGQEEK 823
Score = 51.6 bits (122), Expect = 6e-06
Identities = 31/124 (25%), Positives = 72/124 (58%), Gaps = 3/124 (2%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
QE + ++ L + ++ +K+ +QEE + ++ K+ R++ E +K+ +E ++
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEE--KMREQEEKMWRQEERLWEQEKQMREQEQ 390
Query: 347 KKREELKKIVEE-ERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECD 405
K R++ +++ E+ ERL++KEE+ R + + ++ EK+REEK+ + K + + E +
Sbjct: 391 KMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE 450
Query: 406 DLKE 409
++E
Sbjct: 451 RIRE 454
Score = 51.6 bits (122), Expect = 6e-06
Identities = 45/172 (26%), Positives = 85/172 (49%), Gaps = 27/172 (15%)
Query: 643 QAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADIS 702
+ K + +E K K REE + R R E+K++E+E+ M+E++EK++E E++ +
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMRER---EKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Query: 703 IGEEEREDFDTSIESKDTEQKEL--------------DQDMVTEDEDDPGSHKRGRRGK- 747
+ E+E + ++ E K EQ+ L +Q+ + E E+ + RG+
Sbjct: 750 MWEQEEKMWEQ--EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Query: 748 ---RGQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQR--KEKELLEKIQ 794
RGQ ++ QE+ E + EE+ QE + +E+++ EK+Q
Sbjct: 808 EKMRGQE--EKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQ 857
Score = 50.8 bits (120), Expect = 1e-05
Identities = 37/159 (23%), Positives = 84/159 (52%), Gaps = 13/159 (8%)
Query: 278 RPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEM-----KSLAFEKAKLK--RE 330
R K + +E ++ + K ++ +K+ +QEE K + ++ K++ E
Sbjct: 338 REQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397
Query: 331 KADALEAKKKEKEDK----EKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKR 386
+ + + +EKE++ EK E+++K+ EE++++++E+K R + E+ +E E++RE ++
Sbjct: 398 RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREK 457
Query: 387 KYVEYLKQWSKPREDMEC--DDLKELPEPTPVKTRLPPE 423
K E + + E M+ +++ E E + RLP +
Sbjct: 458 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496
Score = 49.7 bits (117), Expect = 2e-05
Identities = 31/117 (26%), Positives = 69/117 (58%), Gaps = 3/117 (2%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
QE+ + ++ + + ++++KL + E+M+ EK + + EK E +K+ +++E
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ--EKMQEQEEKIWEQEKMEKKTQEQE 700
Query: 347 KKREELKKIVEEERLKKKEEKERLKVEREKER-EKLREEKRKYVEYLKQWSKPREDM 402
KK + +K+ EEE ++++E+K R + E +E+ EK++E++ K E ++ + E M
Sbjct: 701 KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKM 757
Score = 49.3 bits (116), Expect = 3e-05
Identities = 38/148 (25%), Positives = 77/148 (52%), Gaps = 16/148 (10%)
Query: 642 RQAKQEFRELKAEQHRKEREEAAARIRKR-KEEKLKEQEQKMKEKQEKLKEDEQRNSTAD 700
+ +QE + + E+ +++EE + +K ++EK++EQE +M E++EK+++ EQ+
Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK----- 559
Query: 701 ISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQE 760
+EER + T ++ E+K DQ+ +E+ ++ R + +E QE
Sbjct: 560 -MWDQEERMEKKT----QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 761 QINCVTREPLTADEEEALKQEHQRKEKE 788
Q E + EE+ +QE + +E+E
Sbjct: 615 Q-----EEKMQEQEEKMWEQEEKMQEQE 637
Score = 48.1 bits (113), Expect = 6e-05
Identities = 33/129 (25%), Positives = 73/129 (56%), Gaps = 2/129 (1%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
QE+ + ++ + K +E++K L++++ E+ + + EK E K +E+E+K
Sbjct: 312 QEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKM 371
Query: 347 KKREELKKIVEEERLKKKEEKERLKVEREKER-EKLREEKRKYVEYLKQWSKPREDMECD 405
++EE + +E++++++E+K R + ER E+ E+LRE++ + E K W + + E
Sbjct: 372 WRQEE-RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEK 430
Query: 406 DLKELPEPT 414
++E + T
Sbjct: 431 KMQEQEKKT 439
Score = 47.0 bits (110), Expect = 1e-04
Identities = 39/164 (23%), Positives = 83/164 (50%), Gaps = 17/164 (10%)
Query: 645 KQEFRELKAEQHRKEREEAAARIRKR---KEEKLKEQEQKMKEKQEKLKEDEQRNSTADI 701
+QE + + E+ +E+EE R +R +E++++EQEQKM++++E++ E ++R +
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411
Query: 702 SIGEEER--EDFDTSIESK----------DTEQKELDQDMVTEDEDDPGSHKRGRRGKRG 749
+ E+E+ E + E K D E+K +++ + E E + R +
Sbjct: 412 RMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEE 471
Query: 750 QNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEKI 793
+ +E EQ ++ +++E L ++ + +E+E EKI
Sbjct: 472 KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE--EKI 513
Score = 47.0 bits (110), Expect = 1e-04
Identities = 44/174 (25%), Positives = 87/174 (50%), Gaps = 31/174 (17%)
Query: 645 KQEFRELKAEQHRKEREEAA---ARIRKRKE-----EKLKEQEQKMKEKQEKLKEDEQ-- 694
+QE + K E++ E+EE R+ ++KE EK++EQE+K+ E++EK+++ E+
Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 527
Query: 695 ---RNSTADISIGEEEREDFDTSIESKDTEQKELDQD-----------MVTEDEDDPGSH 740
+ + E+E + ++ + +D EQK DQ+ T D+++
Sbjct: 528 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE---- 583
Query: 741 KRGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEKIQ 794
+ R +R + K+ +E++ E + EE+ +QE + E+E EK+Q
Sbjct: 584 -KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE--EKMQ 634
Score = 46.6 bits (109), Expect = 2e-04
Identities = 42/161 (26%), Positives = 81/161 (50%), Gaps = 6/161 (3%)
Query: 630 TRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKR--KEEKLKEQEQKMKEKQE 687
TRD E + R ++E + + E+ +E+EE + + ++E+ + Q+Q++ E++E
Sbjct: 439 TRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 498
Query: 688 KLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGK 747
KL E E+ + I E+E + D E E+K Q+ + E ED + R +
Sbjct: 499 KLWEQEKMQEQEE-KIWEQEEKIRDQE-EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 748 RGQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKE 788
Q + + R E+ +E T D+EE +++E + +E+E
Sbjct: 557 E-QKMWDQEERMEK-KTQEQEKKTWDQEEKMREEERMRERE 595
Score = 46.6 bits (109), Expect = 2e-04
Identities = 29/108 (26%), Positives = 67/108 (62%), Gaps = 8/108 (7%)
Query: 306 KERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVE-EERLKKK 364
+ER+K +++EE + + ++ K++ ++ E ++K E +EK +E+ +K+ E EE++ ++
Sbjct: 592 REREKKMREEE-EMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 365 EEK----ERLKVEREK--EREKLREEKRKYVEYLKQWSKPREDMECDD 406
EEK +RL ++EK E EK++E+++ + K W + + + + +
Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/123 (26%), Positives = 67/123 (54%), Gaps = 13/123 (10%)
Query: 287 QEDNVANKQTLASYRSKA-----TKERDKLLKQEEM--KSLAFEKAKLKREKADALEAKK 339
QE+ + +Q L + K +E++K+ +QEE + EK ++EK + K
Sbjct: 650 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKM 709
Query: 340 KEKE---DKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWS 396
+E+E ++EKK E ++++ E+ K +E++E+++ E+E E +E++ + + K W
Sbjct: 710 REEESMREREKKMREEEEMMREQEEKMQEQEEKMQ---EQEEEMWEQEEKMWEQEEKMWE 766
Query: 397 KPR 399
+ R
Sbjct: 767 QQR 769
Score = 46.2 bits (108), Expect = 2e-04
Identities = 28/121 (23%), Positives = 71/121 (58%), Gaps = 5/121 (4%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
Q++ + K+ + K ++ +K+ ++++M+ E+ K R++ + ++ +++ +E ++
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKKMQ----EQEKKTRDQEEKMQEEERIREREK 457
Query: 347 KKREELKKIVE-EERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECD 405
K REE + + E EE+++K+EE + E+E ++++L E+K K E K + + E +
Sbjct: 458 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517
Query: 406 D 406
+
Sbjct: 518 E 518
Score = 45.8 bits (107), Expect = 3e-04
Identities = 36/142 (25%), Positives = 69/142 (48%), Gaps = 19/142 (13%)
Query: 281 KRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAK-- 338
K++ +E ++ + K ++ +K+ +QEE EK + EK E K
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 339 -------KKEK-------EDKEKKREELKKIVEEERLKKK---EEKERLKVEREKEREKL 381
+KEK +++EK +E+ +KI E+E+++KK +EK+ E+ +E E +
Sbjct: 656 EQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715
Query: 382 REEKRKYVEYLKQWSKPREDME 403
RE ++K E + + E M+
Sbjct: 716 REREKKMREEEEMMREQEEKMQ 737
Score = 45.4 bits (106), Expect = 4e-04
Identities = 31/128 (24%), Positives = 69/128 (53%), Gaps = 6/128 (4%)
Query: 287 QEDNV-ANKQTLASYRSKATKERDKLLKQ-EEMKSLAFEKAKLKREKADALEAKKKEKED 344
QED + ++ + K + +++ K+ +E + +++ + RE+ E +KK +E+
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 345 KEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMEC 404
+E RE+ +K+ E+E K +E++E++ + EK +E +E++ + + K W + + E
Sbjct: 602 EEMMREQEEKMQEQEE-KMQEQEEKMWEQEEKMQE---QEEKMWEQEEKMWEQEEKMWEQ 657
Query: 405 DDLKELPE 412
L E E
Sbjct: 658 QRLPEQKE 665
Score = 45.4 bits (106), Expect = 4e-04
Identities = 41/149 (27%), Positives = 70/149 (46%), Gaps = 6/149 (4%)
Query: 646 QEFRELKAEQHRK--EREEAAARIRKR---KEEKLKEQEQKMKEKQEKLKEDEQRNSTAD 700
QE E EQ K E+EE ++ +EEK+ EQE+KM E+Q ++ E+
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 672
Query: 701 ISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTR-Q 759
+ E+ +E + E + E+K +Q+ T D++ + R ++ +E R Q
Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ 732
Query: 760 EQINCVTREPLTADEEEALKQEHQRKEKE 788
E+ E + EEE +QE + E+E
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQE 761
Score = 45.4 bits (106), Expect = 4e-04
Identities = 28/103 (27%), Positives = 58/103 (56%), Gaps = 8/103 (7%)
Query: 301 RSKATKERDKLLKQEEMKSLAFEKAKLK------REKADALEAKKKEKEDKEKKREELKK 354
+ K ++ +K+ +QE+M+ E+ K RE+ E +KK +E++E RE+ +K
Sbjct: 676 QEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEK 735
Query: 355 IVEEERLKKKEEKERLKVERE--KEREKLREEKRKYVEYLKQW 395
+ E+E +++E+E + E + ++ EK+ E++R + K W
Sbjct: 736 MQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 778
Score = 44.7 bits (104), Expect = 7e-04
Identities = 31/146 (21%), Positives = 72/146 (49%), Gaps = 12/146 (8%)
Query: 279 PPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEM------------KSLAFEKAK 326
P + + QE+ ++ L K K+ +K+ +QEE + + ++ +
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR 322
Query: 327 LKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKR 386
L+ ++ + E +K+ +E KE + +E + +EE++ ++EEK R + E+ +E+ E+
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 382
Query: 387 KYVEYLKQWSKPREDMECDDLKELPE 412
K + +Q + +E+ + + L E
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLRE 408
Score = 44.7 bits (104), Expect = 7e-04
Identities = 27/114 (23%), Positives = 63/114 (55%), Gaps = 7/114 (6%)
Query: 306 KERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKE 365
K RD+ K +E + + + K++ E+ E ++K ++ +E E+ +K +++RL +++
Sbjct: 438 KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 497
Query: 366 EK----ERLKVEREK---EREKLREEKRKYVEYLKQWSKPREDMECDDLKELPE 412
EK E+++ + EK + EK+R+++ + + K W + + + D + E E
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE 551
Score = 44.7 bits (104), Expect = 7e-04
Identities = 33/157 (21%), Positives = 80/157 (50%), Gaps = 6/157 (3%)
Query: 642 RQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADI 701
+ +QE + + E+ +++E+ +R E+K +EQE+K +++EK++E+E+
Sbjct: 538 KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK 597
Query: 702 SIGEEE--REDFDTSIES----KDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKE 755
EEE RE + E ++ E+K +Q+ +++++ + + ++ + +++
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 756 FTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEK 792
EQ + ++E+ +QE + E+E +EK
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK 694
Score = 43.5 bits (101), Expect = 0.002
Identities = 38/149 (25%), Positives = 80/149 (53%), Gaps = 13/149 (8%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKA-DALEAKKKEKEDK 345
QE+ + +++ + K ++ +K+ +QE+ EK + + +K D E +K+ +++
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQ-EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574
Query: 346 EKKR-EELKKIVEEERL----KKKEEKERLKVERE----KEREKLREEKRKYVEYLKQWS 396
EKK ++ +K+ EEER+ KK E+E + E+E ++ EK++E++ K E ++
Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQ 634
Query: 397 KPREDM--ECDDLKELPEPTPVKTRLPPE 423
+ E M + + + E E + RLP +
Sbjct: 635 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663
Score = 43.5 bits (101), Expect = 0.002
Identities = 32/114 (28%), Positives = 65/114 (57%), Gaps = 11/114 (9%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
QE+ + K + K T ++++ +++EE +K + + E E K +E+E+K
Sbjct: 563 QEERMEKK---TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 619
Query: 347 KKREELKKIVEEERLKKKEEK-----ERLKVEREK--EREKLREEKRKYVEYLK 393
+++EE K +EE+++++EEK E++ + EK E+++L E+K K E+ K
Sbjct: 620 QEQEE-KMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 672
Score = 43.5 bits (101), Expect = 0.002
Identities = 25/93 (26%), Positives = 57/93 (61%), Gaps = 9/93 (9%)
Query: 301 RSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEER 360
+ K T +++K+ ++E M+ E+ K RE+ + + ++++ +++E+K +E +EE
Sbjct: 699 QEKKTWDQEKMREEESMR----EREKKMREEEEMMREQEEKMQEQEEKMQE-----QEEE 749
Query: 361 LKKKEEKERLKVEREKEREKLREEKRKYVEYLK 393
+ ++EEK + E+ E+++L E+K K E+ K
Sbjct: 750 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 782
Score = 43.1 bits (100), Expect = 0.002
Identities = 38/154 (24%), Positives = 81/154 (52%), Gaps = 16/154 (10%)
Query: 645 KQEFRELKAEQHRKEREEAA----ARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTAD 700
+QE + + EQ +++EE R+R+ KEE+++EQE KM E+ EK++E+++
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLRE-KEERMREQE-KMWEQVEKMREEKKMQEQEK 437
Query: 701 ISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQE 760
+ +EE+ + I ++ + +E ++ M ++E + K+ +N +++ ++
Sbjct: 438 KTRDQEEKMQEEERIREREKKMREEEETMREQEE---------KMQKQEENMWEQEEKEW 488
Query: 761 QINCVTREPLTADEEEALKQEHQRKEKELLEKIQ 794
Q + + E+E + QE + K E EKI+
Sbjct: 489 QQQRLPEQKEKLWEQEKM-QEQEEKIWEQEEKIR 521
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/133 (24%), Positives = 69/133 (51%), Gaps = 15/133 (11%)
Query: 281 KRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKK 340
+++ +E ++ + K ++ +K+ +QEE +E+ +L +K E +K
Sbjct: 617 EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM---WEQQRLPEQKEKLWEHEKM 673
Query: 341 EKEDKEKKREELKKIVEEERLKKKEEKERLKV---------EREKEREKL-REEKRKYVE 390
++++K +++EE KI E+E+++KK +++ K E +EREK REE+ E
Sbjct: 674 QEQEKMQEQEE--KIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMRE 731
Query: 391 YLKQWSKPREDME 403
++ + E M+
Sbjct: 732 QEEKMQEQEEKMQ 744
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/111 (28%), Positives = 60/111 (54%), Gaps = 11/111 (9%)
Query: 287 QEDNVANKQTLASYRSKA-----TKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKE 341
QE+ + +Q L + K +E++K+ +QEE EK + + EK E K +
Sbjct: 760 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRG 819
Query: 342 KEDKEKKREELKKIVEEERLKKKEEK-----ERLKVEREKEREKLREEKRK 387
+E+K +EE K +EE++ +EEK E+++ + + + EK+RE++ K
Sbjct: 820 QEEKMWGQEE-KMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEK 869
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/138 (23%), Positives = 73/138 (52%), Gaps = 21/138 (15%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKS----LAFEKAKLK-------REKADAL 335
QE+N+ ++ + + ++++KL +QE+M+ + ++ K++ +EK
Sbjct: 476 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 535
Query: 336 EAKKKEKEDKEKKREELKKIVE------EERLKKKEEKERLKV----EREKEREKLREEK 385
+ K +E+ED+ ++EE + E EER++KK +++ K E+ +E E++RE +
Sbjct: 536 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRERE 595
Query: 386 RKYVEYLKQWSKPREDME 403
+K E + + E M+
Sbjct: 596 KKMREEEEMMREQEEKMQ 613
Score = 42.7 bits (99), Expect = 0.003
Identities = 39/178 (21%), Positives = 86/178 (48%), Gaps = 13/178 (7%)
Query: 641 LRQAKQEFRELKAE-QHRKEREEAAARIRKRKEEKLKEQEQKM------KEKQEKLKEDE 693
+R+ ++ RE + + Q ++E+ + +EEK+ EQE+KM E++EKL E E
Sbjct: 722 MREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 781
Query: 694 QRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKR--GRRGKRGQN 751
+ I EE+ D + + ++ + + ++ M ++E G ++ G+ K
Sbjct: 782 KMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQ 841
Query: 752 GFKEFTRQEQI--NCVTREPLTADEEEALK--QEHQRKEKELLEKIQSAIACTNIFPL 805
K + ++E++ +E ++EE ++ +E R+++E + + I C P+
Sbjct: 842 EEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCVGSPPI 899
Score = 42.4 bits (98), Expect = 0.004
Identities = 28/107 (26%), Positives = 65/107 (60%), Gaps = 4/107 (3%)
Query: 303 KATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLK 362
++ +ER+K +++EE + + ++ K++ ++ E +++ E +EK E+ +K+ E++RL
Sbjct: 713 ESMREREKKMREEE-EMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Query: 363 KKEEKERL-KVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLK 408
E+KE+L + E+ +E+EK+ E++ K + ++ E M + K
Sbjct: 772 --EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEK 816
Score = 39.7 bits (91), Expect = 0.023
Identities = 28/111 (25%), Positives = 63/111 (56%), Gaps = 11/111 (9%)
Query: 288 EDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDK-- 345
++ + ++++ K +E + + +QEE EK + + E+ E K E+E+K
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMW 765
Query: 346 EKKR--EELKKIVEEERLKKK----EEKERLKVEREKER---EKLREEKRK 387
E++R E+ +K+ E E+++++ E++E+++ + EK R EK+R ++ K
Sbjct: 766 EQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEK 816
Score = 38.9 bits (89), Expect = 0.039
Identities = 29/114 (25%), Positives = 60/114 (52%), Gaps = 6/114 (5%)
Query: 279 PPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAK 338
P ++ + + + + ++ + K + +K+ QEE EK + + EK E K
Sbjct: 771 PEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830
Query: 339 KKEKEDKEKKREELKKIVEEERLKKK--EEKERLKVEREKER---EKLREEKRK 387
+E+K +EE K +EE++++K ++E+++ + EK R EK+RE++ K
Sbjct: 831 MWGQEEKMWGQEE-KMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883
Score = 38.1 bits (87), Expect = 0.067
Identities = 27/123 (21%), Positives = 65/123 (52%), Gaps = 7/123 (5%)
Query: 281 KRIHISQEDNVANKQTLASYRSKATKERDKLLKQEE----MKSLAFEKAKLKREKADALE 336
K++ +E ++ + K ++ +++ +QEE + +E+ +L +K E
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 779
Query: 337 AKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVE--REKEREKLREEKRKYVEYLKQ 394
+K ++++K ++EE K +EE+++ +EEK R + E R +E + +E++ + + K
Sbjct: 780 HEKMQEQEKIWEQEE-KMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKM 838
Query: 395 WSK 397
W +
Sbjct: 839 WGQ 841
Score = 37.7 bits (86), Expect = 0.087
Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDK- 345
QE ++ + K + +K+ QEE EK + EK E K +E+K
Sbjct: 786 QEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKM 845
Query: 346 ---EKKREELKKIVEEERLKKKEEKERLKVEREKER-EKLREEKRK 387
E+K EE K +EE+++++EEK R + E+ +E+ EK+R ++ K
Sbjct: 846 WGQEEKMEE-KMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 37.0 bits (84), Expect = 0.15
Identities = 33/145 (22%), Positives = 74/145 (51%), Gaps = 17/145 (11%)
Query: 281 KRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKS-----LAFEKAKL-KREKADA 334
+RI ++ ++T+ K K+ + + ++E K L +K KL ++EK
Sbjct: 450 ERIREREKKMREEEETMREQEEKMQKQEENMW-EQEEKEWQQQRLPEQKEKLWEQEKMQE 508
Query: 335 LEAKKKEKEDKEKKREEL----KKIVEEERLKKKEEKERLKVEREKEREKL------REE 384
E K E+E+K + +EE+ KK+ +E+++++E++ + E+ +++E+ R E
Sbjct: 509 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERME 568
Query: 385 KRKYVEYLKQWSKPREDMECDDLKE 409
K+ + K W + + E + ++E
Sbjct: 569 KKTQEQEKKTWDQEEKMREEERMRE 593
Score = 35.8 bits (81), Expect = 0.33
Identities = 31/104 (29%), Positives = 62/104 (59%), Gaps = 7/104 (6%)
Query: 303 KATKERDK-LLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEE-R 360
K ER K LL Q + +L E + R++ + E +KK ++ +EK + +++ E+E +
Sbjct: 252 KRKLERAKFLLPQVQTNTLQEE---MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 308
Query: 361 LKKKEEKERLKVEREKEREK-LREEKRKYVEYLKQWSKPREDME 403
++++EEK + +R +E+EK LRE++++ E K+ + E M+
Sbjct: 309 MREQEEKMWRQEKRLREQEKELREQEKELREQ-KELREQEEQMQ 351
Score = 35.0 bits (79), Expect = 0.57
Identities = 31/128 (24%), Positives = 63/128 (49%), Gaps = 15/128 (11%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
QE+ + ++ + + ++++KL + E+M+ EK + EK E K + +E+K
Sbjct: 753 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ--EKIWEQEEKMRDQEEKMRGQEEKM 810
Query: 347 KKREELKKIVEEERLKKKEEK------------ERLKVEREKEREKLREEKRKYVEYLKQ 394
+ +EE K +EE++ +EEK E++ + EK EK++ ++ K E ++
Sbjct: 811 RGQEE-KMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEK 869
Query: 395 WSKPREDM 402
E M
Sbjct: 870 MRGQEEKM 877
Score = 33.9 bits (76), Expect = 1.3
Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 26/137 (18%)
Query: 300 YRSKATKERDKLLKQEEMKSLAFEKAKLKR-EKADALEAKKKEKEDKEKKREELKKIVE- 357
Y + TKERD L + ++ E+ K K E + L + EK + + +ELK+ +E
Sbjct: 198 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLER 257
Query: 358 --------------EERLKKKEE--KERLKVEREKER-----EKLREEKRKYVEY-LKQW 395
EE +++EE ++ K+ +++E+ E+LRE++ K E K W
Sbjct: 258 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMW 317
Query: 396 SKPREDMECDDLKELPE 412
+ + E + KEL E
Sbjct: 318 RQEKRLREQE--KELRE 332
Score = 33.5 bits (75), Expect = 1.6
Identities = 37/134 (27%), Positives = 70/134 (52%), Gaps = 18/134 (13%)
Query: 293 NKQTLASYRSKATKERDKLLKQEEMKS---LAFEKAKLKREKADALEAKKKE---KEDKE 346
N T + K + ++KL E KS L ++ K K E+A L + + +E+
Sbjct: 216 NTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMW 275
Query: 347 KKREELKKIVEEERLKKKEEK-----ERLKVEREKERE---KLREEKRKYVEYLKQWSKP 398
++ EEL++ +E++++K+EEK ERL+ + K RE K+ ++++ E K+ +
Sbjct: 276 RQEEELRE--QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELRE- 332
Query: 399 REDMECDDLKELPE 412
++ E + KEL E
Sbjct: 333 -QEKELREQKELRE 345
Score = 32.7 bits (73), Expect = 2.8
Identities = 18/76 (23%), Positives = 39/76 (51%)
Query: 1196 RPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEE 1255
R ++R R + R E + E+ M +++++ EE+ +EE+ + ++++ QEE
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Query: 1256 EEVSLPKRGRPQVRLP 1271
+ ++ Q RLP
Sbjct: 646 KMWEQEEKMWEQQRLP 661
Score = 32.0 bits (71), Expect = 4.8
Identities = 18/113 (15%), Positives = 54/113 (47%)
Query: 1178 VRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQ 1237
+R K + + E + + + +++ +++ + + +E +++ + E EEE
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEET 465
Query: 1238 SEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQE 1290
E+E ++++ E++ E+EE ++ P+ + + + K+ +Q+E
Sbjct: 466 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518
Score = 31.6 bits (70), Expect = 6.2
Identities = 28/165 (16%), Positives = 71/165 (43%), Gaps = 12/165 (7%)
Query: 1194 ECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQ 1253
E + +++ ++ +++ E ++++ + ++ + E+E Q +E+E ++ + E+ +
Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMR 365
Query: 1254 EEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGR 1313
E+EE K R + RL + + R Q++ R ++ + K
Sbjct: 366 EQEE----KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 421
Query: 1314 SLRKINSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKR 1358
+ K+ E K ++ + TR +Q + E + R K+
Sbjct: 422 QVEKMR-----EEKKMQEQEKKTRDQEEKMQEE---ERIREREKK 458
Score = 31.6 bits (70), Expect = 6.2
Identities = 17/62 (27%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Query: 1198 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEE--GQSEEEEYEVEQDEDDSQEE 1255
+++ R + R E E+ M G+++++ G EE+ GQ E+ E +++ E+ +E+
Sbjct: 807 EEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ 866
Query: 1256 EE 1257
EE
Sbjct: 867 EE 868
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 65.5 bits (158), Expect = 4e-10
Identities = 33/85 (38%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
Query: 1451 SWPFLKLVS--KIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEY 1508
+WPF K V + + DY DIIK P+ ++ I+ K+ EY+ A EF D+ LMFSNC++Y
Sbjct: 373 AWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKY 432
Query: 1509 NPRNTSEAKAGTRLQAFFHIQAQKL 1533
NP + +LQ F ++ K+
Sbjct: 433 NPPDHEVVAMARKLQDVFEMRFAKM 457
Score = 58.5 bits (140), Expect = 5e-08
Identities = 34/118 (28%), Positives = 64/118 (54%), Gaps = 4/118 (3%)
Query: 1395 SKLSLQESESKRRCRKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQLVVE-LVRHDDSWP 1453
S++S +++++ + S P P + ++ ++L ++V++ L +H +WP
Sbjct: 24 SQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQ-TNQLQYLLRVVLKTLWKHQFAWP 82
Query: 1454 FLKLVS--KIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
F + V K+ +PDYY IIK P+ + I++++ Y A E I D MF+NC+ YN
Sbjct: 83 FQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYN 140
Score = 44.3 bits (103), Expect = 0.001
Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 11/151 (7%)
Query: 261 PDDPPTFIFSPANRRRGRPPKRIHI---SQEDNVANKQTLASYRSKATKERDKLLK--QE 315
P++P + SPA PP ++ S + + + S + +ER + L QE
Sbjct: 461 PEEPVVAVSSPAVP----PPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQE 516
Query: 316 EMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVERE 375
++K++ + A L + + + + KKKEK+ KEKK+E+ K+ E E KK + KE + +
Sbjct: 517 QLKAVHEQLAALSQPQQN--KPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTK 574
Query: 376 KEREKLREEKRKYVEYLKQWSKPREDMECDD 406
K +K +K P + E +D
Sbjct: 575 KNNSSNSNVSKKEPAPMKSKPPPTYESEEED 605
Score = 31.2 bits (69), Expect = 8.2
Identities = 22/89 (24%), Positives = 47/89 (52%), Gaps = 5/89 (5%)
Query: 332 ADALEAKKKEKEDKEKKREELKKIVE-EERLKKKEEKERLKVEREKEREKLREEKRKYVE 390
+D+ +D E++R + ++ E +E+LK E+ + ++ + K +E+ +K E
Sbjct: 490 SDSSSDSDSSTDDSEEERAQ--RLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK--E 545
Query: 391 YLKQWSKPREDMECDDLKELPEPTPVKTR 419
K+ K +E++E + + EP P KT+
Sbjct: 546 KKKEKHKRKEEVEENKKSKAKEPPPKKTK 574
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 65.5 bits (158), Expect = 4e-10
Identities = 33/85 (38%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
Query: 1451 SWPFLKLVS--KIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEY 1508
+WPF K V + + DY DIIK P+ ++ I+ K+ EY+ A EF D+ LMFSNC++Y
Sbjct: 373 AWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKY 432
Query: 1509 NPRNTSEAKAGTRLQAFFHIQAQKL 1533
NP + +LQ F ++ K+
Sbjct: 433 NPPDHEVVAMARKLQDVFEMRFAKM 457
Score = 58.5 bits (140), Expect = 5e-08
Identities = 34/118 (28%), Positives = 64/118 (54%), Gaps = 4/118 (3%)
Query: 1395 SKLSLQESESKRRCRKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQLVVE-LVRHDDSWP 1453
S++S +++++ + S P P + ++ ++L ++V++ L +H +WP
Sbjct: 24 SQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQ-TNQLQYLLRVVLKTLWKHQFAWP 82
Query: 1454 FLKLVS--KIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
F + V K+ +PDYY IIK P+ + I++++ Y A E I D MF+NC+ YN
Sbjct: 83 FQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYN 140
Score = 44.3 bits (103), Expect = 0.001
Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 11/151 (7%)
Query: 261 PDDPPTFIFSPANRRRGRPPKRIHI---SQEDNVANKQTLASYRSKATKERDKLLK--QE 315
P++P + SPA PP ++ S + + + S + +ER + L QE
Sbjct: 461 PEEPVVAVSSPAVP----PPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQE 516
Query: 316 EMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVERE 375
++K++ + A L + + + + KKKEK+ KEKK+E+ K+ E E KK + KE + +
Sbjct: 517 QLKAVHEQLAALSQPQQN--KPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTK 574
Query: 376 KEREKLREEKRKYVEYLKQWSKPREDMECDD 406
K +K +K P + E +D
Sbjct: 575 KNNSSNSNVSKKEPAPMKSKPPPTYESEEED 605
Score = 37.4 bits (85), Expect = 0.11
Identities = 26/126 (20%), Positives = 58/126 (46%), Gaps = 7/126 (5%)
Query: 626 TLVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREE---AAARIRKRKEEKLKEQEQKM 682
T S+ D E + R+ ++ + LKA+ E+E+ R+R R++E EQ ++
Sbjct: 1216 TAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRA 1275
Query: 683 KEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKR 742
E+ + +E +Q+ +++++ ++ + T Q + Q D+ + KR
Sbjct: 1276 HEEARRRQEQQQQQRQEQ----QQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKR 1331
Query: 743 GRRGKR 748
+ +R
Sbjct: 1332 EQERRR 1337
Score = 33.5 bits (75), Expect = 1.6
Identities = 18/73 (24%), Positives = 42/73 (57%), Gaps = 2/73 (2%)
Query: 315 EEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVER 374
E+ + A EK + REKA +A+ EKE + ++E ++ +E+ L++ R
Sbjct: 1225 EQFRRAAREKEE--REKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRR 1282
Query: 375 EKEREKLREEKRK 387
++++++ R+E+++
Sbjct: 1283 QEQQQQQRQEQQQ 1295
Score = 32.7 bits (73), Expect = 2.8
Identities = 22/128 (17%), Positives = 57/128 (44%), Gaps = 6/128 (4%)
Query: 273 NRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKA 332
++++ P + ++ + N + AS K K F +A ++E+
Sbjct: 1178 DKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEER 1237
Query: 333 DALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYL 392
+ + E +KEK+R + +ER++ +E+++ L+ R E R ++++ +
Sbjct: 1238 EKALKAQAEHAEKEKER------LRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQ 1291
Query: 393 KQWSKPRE 400
+Q + ++
Sbjct: 1292 EQQQQQQQ 1299
Score = 31.2 bits (69), Expect = 8.2
Identities = 22/89 (24%), Positives = 47/89 (52%), Gaps = 5/89 (5%)
Query: 332 ADALEAKKKEKEDKEKKREELKKIVE-EERLKKKEEKERLKVEREKEREKLREEKRKYVE 390
+D+ +D E++R + ++ E +E+LK E+ + ++ + K +E+ +K E
Sbjct: 490 SDSSSDSDSSTDDSEEERAQ--RLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK--E 545
Query: 391 YLKQWSKPREDMECDDLKELPEPTPVKTR 419
K+ K +E++E + + EP P KT+
Sbjct: 546 KKKEKHKRKEEVEENKKSKAKEPPPKKTK 574
>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
Length = 1544
Score = 64.7 bits (156), Expect = 7e-10
Identities = 23/52 (44%), Positives = 35/52 (67%)
Query: 1151 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSR 1202
C +C D + ++LCDGCD +HT+C+ P L VP+GDW CP+C ++ S+
Sbjct: 312 CLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSK 363
Score = 33.5 bits (75), Expect = 1.6
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 5/52 (9%)
Query: 1152 KICR-KKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEG--DWFCPECRPKQR 1200
KIC +K A M+ C+ C HT CV + ++ +G W CP CR ++
Sbjct: 1177 KICLCQKAPAAPMIQCELCRDAFHTSCV--AVPSISQGLRIWLCPHCRRSEK 1226
>gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive
domain 1B (RBP2-like), partial [Homo sapiens]
Length = 977
Score = 64.7 bits (156), Expect = 7e-10
Identities = 23/52 (44%), Positives = 35/52 (67%)
Query: 1151 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSR 1202
C +C D + ++LCDGCD +HT+C+ P L VP+GDW CP+C ++ S+
Sbjct: 312 CLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSK 363
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 64.7 bits (156), Expect = 7e-10
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 35/107 (32%)
Query: 1151 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRP 1210
C++C++ G+ ++LCD C R +H C+ P+L PEG W CP C
Sbjct: 382 CEVCQQGGE---IILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC--------------- 423
Query: 1211 SLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEE 1257
E +G + E + EEEEYE E +E+ +EEE+
Sbjct: 424 -----------------EKEGVQWEAKEEEEEYEEEGEEEGEKEEED 453
Score = 51.2 bits (121), Expect = 8e-06
Identities = 16/45 (35%), Positives = 27/45 (60%), Gaps = 3/45 (6%)
Query: 1151 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPEC 1195
C++C+ G+ ++ CD C +H +C+ P L +P G+W CP C
Sbjct: 459 CRVCKDGGE---LLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 64.7 bits (156), Expect = 7e-10
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 35/107 (32%)
Query: 1151 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRP 1210
C++C++ G+ ++LCD C R +H C+ P+L PEG W CP C
Sbjct: 382 CEVCQQGGE---IILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC--------------- 423
Query: 1211 SLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEE 1257
E +G + E + EEEEYE E +E+ +EEE+
Sbjct: 424 -----------------EKEGVQWEAKEEEEEYEEEGEEEGEKEEED 453
Score = 51.2 bits (121), Expect = 8e-06
Identities = 16/45 (35%), Positives = 27/45 (60%), Gaps = 3/45 (6%)
Query: 1151 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPEC 1195
C++C+ G+ ++ CD C +H +C+ P L +P G+W CP C
Sbjct: 459 CRVCKDGGE---LLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 64.7 bits (156), Expect = 7e-10
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 35/107 (32%)
Query: 1151 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRP 1210
C++C++ G+ ++LCD C R +H C+ P+L PEG W CP C
Sbjct: 441 CEVCQQGGE---IILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC--------------- 482
Query: 1211 SLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEE 1257
E +G + E + EEEEYE E +E+ +EEE+
Sbjct: 483 -----------------EKEGVQWEAKEEEEEYEEEGEEEGEKEEED 512
Score = 51.2 bits (121), Expect = 8e-06
Identities = 16/45 (35%), Positives = 27/45 (60%), Gaps = 3/45 (6%)
Query: 1151 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPEC 1195
C++C+ G+ ++ CD C +H +C+ P L +P G+W CP C
Sbjct: 518 CRVCKDGGE---LLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 559
Score = 37.7 bits (86), Expect = 0.087
Identities = 18/48 (37%), Positives = 30/48 (62%), Gaps = 2/48 (4%)
Query: 1210 PSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEE 1257
P + +E+ E+ + E++E + EEEG EEEE DEDD ++++E
Sbjct: 4 PLRDEEEEEEEMVVSEEEEEE--EEEGDEEEEEEVEAADEDDEEDDDE 49
Score = 31.6 bits (70), Expect = 6.2
Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Query: 689 LKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKR 748
L+++E+ ++ + EEE E+ + E ++ E + D+D E++DD G RG R
Sbjct: 5 LRDEEEEEE--EMVVSEEEEEEEEEGDEEEEEEVEAADED--DEEDDDEGVLGRGPGHDR 60
Query: 749 GQN 751
G++
Sbjct: 61 GRD 63
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 64.3 bits (155), Expect = 9e-10
Identities = 34/148 (22%), Positives = 80/148 (54%)
Query: 641 LRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTAD 700
+R+ +++ R + +E+E R+++KL+EQE++M+E++EK+ E E++ +
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 701 ISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQE 760
+ +E ++ + ++ EQK DQ+ ++D+ K R ++ + +E QE
Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQE 390
Query: 761 QINCVTREPLTADEEEALKQEHQRKEKE 788
+ RE +EEE ++++ ++ +K+
Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQ 418
Score = 59.3 bits (142), Expect = 3e-08
Identities = 38/147 (25%), Positives = 77/147 (52%), Gaps = 4/147 (2%)
Query: 642 RQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADI 701
++ K E E+ +K REE + + +EEK++EQE+KM+E++EK+ E E++ +
Sbjct: 552 QEEKMREEERMREREKKMREEE--EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 702 SIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQ 761
+ E+E + ++ E K EQ+E+ + E++ K + ++ + ++ QE+
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQ--EEKMQEQEEKMWEQEEKMREQEEKMREQEE 667
Query: 762 INCVTREPLTADEEEALKQEHQRKEKE 788
E + EE+ QE + +E+E
Sbjct: 668 KMQGQEEKMREQEEKMQGQEEKMREQE 694
Score = 58.2 bits (139), Expect = 6e-08
Identities = 40/158 (25%), Positives = 83/158 (52%), Gaps = 4/158 (2%)
Query: 641 LRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTAD 700
LR+ ++E RE K + ++E+ + +EEK++EQE+KM ++E+L E E++ +
Sbjct: 292 LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351
Query: 701 ISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGR-RGKRGQNGFKEFTRQ 759
+ ++E ++ ++ E++ +Q+ + E E+ +R R R K+ + + Q
Sbjct: 352 QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQ 411
Query: 760 EQINCVTREPLTADEEEALKQEHQRKEKELL---EKIQ 794
E+ E + EE+ +Q+ ++KE L EK+Q
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
Score = 58.2 bits (139), Expect = 6e-08
Identities = 41/157 (26%), Positives = 85/157 (54%), Gaps = 13/157 (8%)
Query: 645 KQEFRELKAEQHRKEREEAA---ARIRKRKE-----EKLKEQEQKMKEKQEKLKEDEQ-- 694
+QE + K E++ E+EE R+ ++KE EK++EQE+K+ E++EK+++ E+
Sbjct: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469
Query: 695 ---RNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQN 751
+ + E+E + ++ + +D EQK DQ+ ++D+ K R ++ +
Sbjct: 470 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM 529
Query: 752 GFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKE 788
+E +E+ +E T D+EE +++E + +E+E
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Score = 56.2 bits (134), Expect = 2e-07
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 14/158 (8%)
Query: 651 LKAEQHRKERE--EAAARIRK------RKEEKLKEQEQKMKEKQEKLKEDEQRNSTADIS 702
L+ E R+E E E +IRK R+EE+L+EQE KM+E++EK++ E+R +
Sbjct: 232 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKE 291
Query: 703 IGEEEREDFDTSIESKDTEQKELDQDMVTEDEDD--PGSHKRGRRGKRGQNGFKEFTRQE 760
+ E+E+E + + EQ + ++ + E E+ K R+ +R K+ QE
Sbjct: 292 LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351
Query: 761 QINCVTREPLTADEEEALKQEHQRKEKELL----EKIQ 794
Q E + +E ++E + +E+E + EK+Q
Sbjct: 352 QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQ 389
Score = 55.5 bits (132), Expect = 4e-07
Identities = 38/148 (25%), Positives = 79/148 (53%), Gaps = 10/148 (6%)
Query: 641 LRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTAD 700
+R+ +++ RE E+ +E+EE + +EEK++EQE+KM E++EK++E E++ +
Sbjct: 562 MREREKKMRE--EEEMMREQEEKM----QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 701 ISIGEEEREDFDTSIESKDTEQKELDQD----MVTEDEDDPGSHKRGRRGKRGQNGFKEF 756
+ E+E ED E EQ+E Q+ M ++E ++ R + G +E
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675
Query: 757 TRQEQINCVTREPLTADEEEALKQEHQR 784
R+++ +E ++EE ++ + ++
Sbjct: 676 MREQEEKMQGQEEKMREQEEKMRGQEEK 703
Score = 53.9 bits (128), Expect = 1e-06
Identities = 29/127 (22%), Positives = 73/127 (57%), Gaps = 4/127 (3%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEM---KSLAFEKAKLKREKADALEAKKKEKE 343
Q++ + ++ + K ++ +K+ QEEM + + + K++ ++ E ++K ++
Sbjct: 438 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD 497
Query: 344 DKEKKREELKKIVEE-ERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDM 402
++K ++ +++ E+ ERL++KEE+ R + + ++ EK+REEK+ + K W + +
Sbjct: 498 QEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMR 557
Query: 403 ECDDLKE 409
E + ++E
Sbjct: 558 EEERMRE 564
Score = 53.1 bits (126), Expect = 2e-06
Identities = 34/109 (31%), Positives = 68/109 (62%), Gaps = 3/109 (2%)
Query: 306 KERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKE 365
+E DK+ +QEEM EK + + EK E K +E+E+K +++EE K +EE+++++E
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE-KMQGQEEKMREQE 680
Query: 366 EKERLKVEREKER-EKLR-EEKRKYVEYLKQWSKPREDMECDDLKELPE 412
EK + + E+ +E+ EK+R +E++ + + K W + + ++++E E
Sbjct: 681 EKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEE 729
Score = 52.0 bits (123), Expect = 4e-06
Identities = 32/135 (23%), Positives = 72/135 (53%), Gaps = 13/135 (9%)
Query: 278 RPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEM-----KSLAFEKAKLKR--- 329
R K++ +E ++ + K ++ +K+ +QEE K + ++ K++
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 330 ---EKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVE--REKEREKLREE 384
E+ + L K++ ++EK E+ +K+ EEER++++E+K R + E RE+E + ++E
Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
Query: 385 KRKYVEYLKQWSKPR 399
+ + + K+W + R
Sbjct: 420 ENMWEQEEKEWQQQR 434
Score = 51.6 bits (122), Expect = 6e-06
Identities = 41/175 (23%), Positives = 89/175 (50%), Gaps = 22/175 (12%)
Query: 639 DILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNST 698
+++R+ +++ +E E+ +E+EE +EEK++EQE+KM E++EK+ E E+ +
Sbjct: 574 EMMREQEEKMQE--QEEKMREQEEK----MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
Query: 699 AD----ISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFK 754
+ + EE+ ++ + + ++ + +E ++ M ++E G ++ R + G +
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687
Query: 755 EFTR--------QEQINCVTREPLTADEEEALKQEHQRKEKELL----EKIQSAI 797
E R QE+ E + EE+ QE R+++E + EK+Q +
Sbjct: 688 EKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL 742
Score = 50.4 bits (119), Expect = 1e-05
Identities = 35/151 (23%), Positives = 76/151 (50%), Gaps = 24/151 (15%)
Query: 281 KRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKK 340
K+I +E ++ L K ++ +K+ +QE K L ++ +L+ ++ + E KK
Sbjct: 248 KKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE--KRLREQEKELREQEKELREQKKL 305
Query: 341 EKEDKEKKREELKKIVEEERLKKKEEK---------ERLKVEREKER------------- 378
+++++ + +E K +EE+++++EEK E+ K RE+E+
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365
Query: 379 EKLREEKRKYVEYLKQWSKPREDMECDDLKE 409
E+LRE++ + E K W + + E + ++E
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIRE 396
Score = 50.1 bits (118), Expect = 2e-05
Identities = 36/147 (24%), Positives = 83/147 (56%), Gaps = 9/147 (6%)
Query: 642 RQAKQEFRELKAEQHRKEREEAAARIRK-RKEEKLKEQEQKMKEKQEKLKEDEQRNSTAD 700
R +Q+ R + E+ +E+E+ + K ++EE+++E+E+KM+E++E ++E E++ +
Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
Query: 701 ISIGEEEREDFDTSIESKDTEQKE--LDQDMVTEDEDDPGSHKRGRRGKRGQNG-FKEFT 757
++ E+E +++ + + EQKE +Q+ + E E+ + R + G K+
Sbjct: 420 ENMWEQEEKEWQ---QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 476
Query: 758 RQEQINCVTREPLTADEEEALKQEHQR 784
RQE++ +E ++EE ++ + Q+
Sbjct: 477 RQEKMR--EQEDQMWEQEEKMRDQEQK 501
Score = 50.1 bits (118), Expect = 2e-05
Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 6/126 (4%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
QE+ + ++ + K +E + + +QEE EK + + EK E K +E+E+K
Sbjct: 552 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM 611
Query: 347 KKREELKKIVEEERLKKKEEKERLKVERE----KEREKLREEKRKYVEYLKQWSKPREDM 402
++EE K+ E+E K +E+E + E+E ++ EK+ E++ K E ++ + E M
Sbjct: 612 WEQEE--KMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669
Query: 403 ECDDLK 408
+ + K
Sbjct: 670 QGQEEK 675
Score = 49.7 bits (117), Expect = 2e-05
Identities = 32/122 (26%), Positives = 69/122 (56%), Gaps = 8/122 (6%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKE--- 343
QE+ + + + + +E+ K+ +QEE K +K + + +K E K +E+E
Sbjct: 505 QEERMWEQDERLREKEERMREQKKMWQQEE-KMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 344 DKEKKREELKKIVEEERLKKKEEKERLKVEREK---EREKLREEKRK-YVEYLKQWSKPR 399
++EKK E ++++ E+ K +E++E+++ + EK + EK++E++ K + + K W +
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623
Query: 400 ED 401
ED
Sbjct: 624 ED 625
Score = 49.3 bits (116), Expect = 3e-05
Identities = 32/120 (26%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
+E ++ + K ++ +K+ +QEE EK + + EK E K +E+E+K
Sbjct: 638 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKM 697
Query: 347 KKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDD 406
+ +EE K +EE++ +EEK + E ++ E++R++K K E L P + C +
Sbjct: 698 RGQEE-KMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL-----PEHEERCSE 751
Score = 48.9 bits (115), Expect = 4e-05
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 8/125 (6%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKED-- 344
QE + ++ + K +E+ KL +QEE EK + EK E K +E+
Sbjct: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340
Query: 345 ----KEKKREELKKIVEEERLKKKEEKERLKVEREKEREKL--REEKRKYVEYLKQWSKP 398
K+ + +E K +EER+ +++E+ R K ER +E+EK+ +EEK + E +++ K
Sbjct: 341 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400
Query: 399 REDME 403
+ E
Sbjct: 401 MREEE 405
Score = 48.1 bits (113), Expect = 6e-05
Identities = 33/98 (33%), Positives = 55/98 (56%), Gaps = 2/98 (2%)
Query: 306 KERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKE 365
K RD+ K + + +E+ + REK + + +KK + +EK REE K +E++ +E
Sbjct: 494 KMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQE 553
Query: 366 EKERLKVEREKERE-KLREEKRKYVEYLKQWSKPREDM 402
EK R + ER +ERE K+REE+ E ++ + E M
Sbjct: 554 EKMR-EEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Score = 48.1 bits (113), Expect = 6e-05
Identities = 29/120 (24%), Positives = 67/120 (55%), Gaps = 7/120 (5%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
QE+ + ++ K + +K+ ++E M+ + K++ E+ E ++K +E +E
Sbjct: 532 QEEKMREEKKTQEQEKKTWDQEEKMREEERMRE---REKKMREEEEMMREQEEKMQEQEE 588
Query: 347 KKREELKKIVE-EERLKKKEEK---ERLKVEREKEREKLREEKRKYVEYLKQWSKPREDM 402
K RE+ +K+ E EE+++++EEK + K+ ++E +K++E++ E ++ + E M
Sbjct: 589 KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM 648
Score = 47.0 bits (110), Expect = 1e-04
Identities = 34/172 (19%), Positives = 84/172 (48%), Gaps = 16/172 (9%)
Query: 634 IEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRK------EEKLKEQEQKMKEKQE 687
I D ++ Q K+ +R+ K + + E ++R ++ EE++ EQ+++++EK+E
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE 521
Query: 688 KLKE-----DEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKR 742
+++E ++ + E+E++ +D + ++ E+ + + E+E+
Sbjct: 522 RMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE-----MM 576
Query: 743 GRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEKIQ 794
+ ++ Q ++ QE+ E + EE+ +QE + E+E +K+Q
Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/118 (25%), Positives = 70/118 (59%), Gaps = 4/118 (3%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
QE+ + +++ + + E+D+ L+++E + +K + EK + +KK +E ++
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK---MREEKKTQEQEK 547
Query: 347 KKREELKKIVEEERLKKKEEKERLKVEREKER-EKLREEKRKYVEYLKQWSKPREDME 403
K ++ +K+ EEER++++E+K R + E +E+ EK++E++ K E ++ + E M+
Sbjct: 548 KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ 605
Score = 47.0 bits (110), Expect = 1e-04
Identities = 33/134 (24%), Positives = 70/134 (52%), Gaps = 4/134 (2%)
Query: 278 RPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEA 337
R +R+ ++ ++ + K ++ +K+ +QEE EK + + EK E
Sbjct: 557 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 616
Query: 338 KKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKER---EKLREEKRKYVEYLKQ 394
K E+E+++K +E+ + + E+E K +E++E++ + EK R EK+RE++ K ++
Sbjct: 617 KMWEQEEEDKMQEQEEMMWEQEE-KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675
Query: 395 WSKPREDMECDDLK 408
+ E M+ + K
Sbjct: 676 MREQEEKMQGQEEK 689
Score = 46.2 bits (108), Expect = 2e-04
Identities = 36/154 (23%), Positives = 76/154 (49%), Gaps = 7/154 (4%)
Query: 641 LRQAKQEFRELKA--EQHRKEREEAAARIRKRK----EEKLKEQEQKMKEKQEKLKEDEQ 694
LR+ ++ RE + EQ K +EE R R++K EE ++EQE+KM +KQE+ +++
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM-QKQEENMWEQE 426
Query: 695 RNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFK 754
+ E++ + ++ + E+ ++ + + E+ G K+ R ++ +
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486
Query: 755 EFTRQEQINCVTREPLTADEEEALKQEHQRKEKE 788
+ QE+ + + EE +Q+ + +EKE
Sbjct: 487 QMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE 520
Score = 45.4 bits (106), Expect = 4e-04
Identities = 38/166 (22%), Positives = 84/166 (50%), Gaps = 20/166 (12%)
Query: 642 RQAKQEFRELKAEQHRKEREEAAARIRK--------RKEEKLKEQEQKMKEKQEKLKEDE 693
+ +QE + + E+ +++EE + +K +E+++ EQE+KM+++++K+ + E
Sbjct: 447 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
Query: 694 QRNSTADISIGEE-----EREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKR 748
+R D + E+ E++ E E+K +Q+ T D+++ + R +R
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE-----KMREEER 561
Query: 749 GQNGFKEFTRQEQINCVTREPLTADEEEALKQEHQRKEKELLEKIQ 794
+ K+ +E++ E + EE+ +QE + E+E EK+Q
Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE--EKMQ 605
Score = 45.1 bits (105), Expect = 5e-04
Identities = 27/133 (20%), Positives = 72/133 (54%), Gaps = 10/133 (7%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
Q++ + K+ + K ++ +K+ ++E ++ + K++ E+ E ++K ++ +E
Sbjct: 364 QDERLREKEERMREQEKMWEQEEKMQEEERIRE---REKKMREEEETMREQEEKMQKQEE 420
Query: 347 KKREELKKIVEEERLKKKEEK----ERLKVEREK---EREKLREEKRKYVEYLKQWSKPR 399
E+ +K +++RL +++EK E+++ + EK + EK+R+++ + + K W + +
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480
Query: 400 EDMECDDLKELPE 412
+ D + E E
Sbjct: 481 MREQEDQMWEQEE 493
Score = 45.1 bits (105), Expect = 5e-04
Identities = 29/116 (25%), Positives = 66/116 (56%), Gaps = 9/116 (7%)
Query: 281 KRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKK 340
+++ +E ++ + K ++ +K+ +QEE E+ K++ ++ E ++K
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEK 640
Query: 341 EKEDKEKKREELKKIVE-EERLKKKEEK-----ERLKVEREK---EREKLREEKRK 387
+E +EK E+ +K+ E EE+++++EEK E+++ + EK + EK+RE++ K
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEK 696
Score = 44.7 bits (104), Expect = 7e-04
Identities = 37/158 (23%), Positives = 79/158 (50%), Gaps = 24/158 (15%)
Query: 281 KRIHISQEDNVANKQTLASYRSKATKERDKLLKQEE----MKSLAFEKAKL-KREKADAL 335
+RI ++ ++T+ K K+ + + +QEE + L +K KL ++EK
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 336 EAKKKEKEDKEKKREEL----KKIVEEERLKKKEEK-----ERLKVEREK---------- 376
E K E+E+K + +EE+ KK+ +E+++++E++ E+++ + +K
Sbjct: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE 511
Query: 377 EREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPT 414
+ E+LRE++ + E K W + + E +E + T
Sbjct: 512 QDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Score = 44.7 bits (104), Expect = 7e-04
Identities = 37/155 (23%), Positives = 77/155 (49%), Gaps = 5/155 (3%)
Query: 642 RQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADI 701
++ K +E K + E R+R+ KEE+++EQ+ KM +++EK++E+++
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLRE-KEERMREQK-KMWQQEEKMREEKKTQEQEKK 548
Query: 702 SIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQ 761
+ +EE+ + + ++ + +E +++M+ E E+ + R + + +E QEQ
Sbjct: 549 TWDQEEKMREEERMREREKKMRE-EEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ 607
Query: 762 INCV--TREPLTADEEEALKQEHQRKEKELLEKIQ 794
+ E + EEE QE + E EK+Q
Sbjct: 608 EEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ 642
Score = 44.3 bits (103), Expect = 0.001
Identities = 35/146 (23%), Positives = 70/146 (47%), Gaps = 12/146 (8%)
Query: 279 PPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEE----MKSLAFEKAKLKREKADA 334
P + + QE+ ++ L K K+ +K+ +QEE + E+ + R +
Sbjct: 225 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKR 284
Query: 335 LEAKKKEKEDKEKKREELKKIVE--------EERLKKKEEKERLKVEREKEREKLREEKR 386
L ++KE ++EK+ E KK+ E EE++ ++EEK R + E+ +E+ E+
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
Query: 387 KYVEYLKQWSKPREDMECDDLKELPE 412
K + +Q + +E+ + + L E
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLRE 370
Score = 44.3 bits (103), Expect = 0.001
Identities = 30/111 (27%), Positives = 67/111 (60%), Gaps = 10/111 (9%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
QE + +++ + + +E+++ ++++E +E+ + +E+ E +KK +E++E
Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMREQEK---MWEQEEKMQEEERIREREKKMREEEE 406
Query: 347 KKREELKKI-VEEERLKKKEEKE----RLKVEREK--EREKLREEKRKYVE 390
RE+ +K+ +EE + ++EEKE RL ++EK E+EK++E++ K E
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 457
Score = 43.5 bits (101), Expect = 0.002
Identities = 29/153 (18%), Positives = 81/153 (52%), Gaps = 6/153 (3%)
Query: 641 LRQAKQEFRELKAEQHRKERE-EAAARIRKRKE----EKLKEQEQKMKEKQEKLKEDEQR 695
L + K++ E + Q ++E+ E +IR ++E EK +++KM+E+++++ E E++
Sbjct: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
Query: 696 NSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKE 755
+ + ++E ++ ++ E++ +Q + + E+ K+ + ++ +E
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE 554
Query: 756 FTRQEQINCVTREPLTADEEEALKQEHQRKEKE 788
R+E+ RE +EEE ++++ ++ +++
Sbjct: 555 KMREEE-RMREREKKMREEEEMMREQEEKMQEQ 586
Score = 40.8 bits (94), Expect = 0.010
Identities = 31/113 (27%), Positives = 56/113 (49%), Gaps = 7/113 (6%)
Query: 301 RSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEER 360
R + K RD+ + E EK + RE+ E ++K +E++ + E K EEE
Sbjct: 348 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEET 407
Query: 361 LKKKEEK-----ERLKVEREKE--REKLREEKRKYVEYLKQWSKPREDMECDD 406
++++EEK E + + EKE +++L E+K K E K + + E ++
Sbjct: 408 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Score = 40.0 bits (92), Expect = 0.018
Identities = 27/128 (21%), Positives = 68/128 (53%), Gaps = 12/128 (9%)
Query: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
QE+ + +++ + K ++ +K+ +QE+ EK + + +K E + E++++
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQ-EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL 516
Query: 347 KKREEL-----------KKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQW 395
+++EE +K+ EE++ +++E+K + E+ +E E++RE ++K E +
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576
Query: 396 SKPREDME 403
+ E M+
Sbjct: 577 REQEEKMQ 584
Score = 39.7 bits (91), Expect = 0.023
Identities = 33/104 (31%), Positives = 63/104 (60%), Gaps = 10/104 (9%)
Query: 303 KATKERDK-LLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEE-R 360
K ER K LL Q + +L E + R++ + E +KK ++ +EK + +++ E+E +
Sbjct: 214 KRKLERAKFLLPQVQTNTLQEE---MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 270
Query: 361 LKKKEEKERLKVEREKEREK-LREEKRKYVEYLKQWSKPREDME 403
++++EEK R + +R +E+EK LRE++++ L++ K RE E
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKE----LREQKKLREQEE 310
Score = 39.3 bits (90), Expect = 0.030
Identities = 29/139 (20%), Positives = 76/139 (54%), Gaps = 7/139 (5%)
Query: 275 RRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADA 334
++ R + + QE+ + ++ + + E+++ ++++E K E+ ++E+ D
Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK 626
Query: 335 LEAKKKEK-EDKEKKREELKKIVEEERLKKK-EEKERLKVEREK---EREKLREEKRKYV 389
++ +++ E +EK +E+ +K+ E+E +K E++E+++ + EK + EK+RE++ K
Sbjct: 627 MQEQEEMMWEQEEKMQEQEEKMWEQE--EKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Query: 390 EYLKQWSKPREDMECDDLK 408
++ + E M + K
Sbjct: 685 GQEEKMREQEEKMRGQEEK 703
Score = 36.2 bits (82), Expect = 0.25
Identities = 23/98 (23%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Query: 281 KRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKK 340
+++ +E ++ + K ++ +K+ QEE EK + + EK E K
Sbjct: 653 EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMW 712
Query: 341 EKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKER 378
+E+K +EE+++ +EER++ ++EK + ++ +ER
Sbjct: 713 GQEEKMWGQEEMRE--KEERIRDQKEKMQERLPEHEER 748
Score = 35.4 bits (80), Expect = 0.43
Identities = 37/134 (27%), Positives = 71/134 (52%), Gaps = 18/134 (13%)
Query: 293 NKQTLASYRSKATKERDKLLKQEEMKS---LAFEKAKLKREKADALEAKKKE---KEDKE 346
N T + K + ++KL E KS L ++ K K E+A L + + +E+
Sbjct: 178 NTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMW 237
Query: 347 KKREELKKIVEEERLKKKEEK-----ERLKVEREKERE---KLREEKRKYVEYLKQWSKP 398
++ EEL++ +E++++K+EEK ERL+ + K RE K+R ++++ E K+ +
Sbjct: 238 RQEEELRE--QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELRE- 294
Query: 399 REDMECDDLKELPE 412
++ E + K+L E
Sbjct: 295 -QEKELREQKKLRE 307
Score = 33.5 bits (75), Expect = 1.6
Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 21/121 (17%)
Query: 300 YRSKATKERDKLLKQEEMKSLAFEKAKLKR-EKADALEAKKKEKEDKEKKREELKKIVE- 357
Y + TKERD L + ++ E+ K K E + L + EK + + +ELK+ +E
Sbjct: 160 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLER 219
Query: 358 --------------EERLKKKEE-KERLKVEREKEREKLREEKRKYVEYLKQWSKPREDM 402
EE +++EE +E+ K R++E + R+E+R +Q K RE
Sbjct: 220 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER----LREQEGKMREQE 275
Query: 403 E 403
E
Sbjct: 276 E 276
Score = 32.3 bits (72), Expect = 3.7
Identities = 19/86 (22%), Positives = 43/86 (50%), Gaps = 10/86 (11%)
Query: 1183 KTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDV----------EDSMGGEDDEVDGD 1232
KT + + E R ++R +++ + E +E + E+ M +++++
Sbjct: 548 KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ 607
Query: 1233 EEEGQSEEEEYEVEQDEDDSQEEEEV 1258
EE+ +EE+ +++ED QE+EE+
Sbjct: 608 EEKMWEQEEKMWEQEEEDKMQEQEEM 633
Score = 32.3 bits (72), Expect = 3.7
Identities = 17/72 (23%), Positives = 40/72 (55%), Gaps = 3/72 (4%)
Query: 1194 ECRPKQRSRRLSSRQRPSLESDEDV---EDSMGGEDDEVDGDEEEGQSEEEEYEVEQDED 1250
E + +++ ++ ++ E +E + E+ M G+++++ G EE+ +EE E E+
Sbjct: 673 EEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIR 732
Query: 1251 DSQEEEEVSLPK 1262
D +E+ + LP+
Sbjct: 733 DQKEKMQERLPE 744
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,291,434
Number of Sequences: 37866
Number of extensions: 3160633
Number of successful extensions: 74221
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1034
Number of HSP's successfully gapped in prelim test: 1127
Number of HSP's that attempted gapping in prelim test: 19611
Number of HSP's gapped (non-prelim): 28772
length of query: 1556
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1440
effective length of database: 13,855,062
effective search space: 19951289280
effective search space used: 19951289280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.