BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] (2063 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 4147 0.0 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 118 7e-26 gi|163965366 nascent polypeptide-associated complex alpha subuni... 105 5e-22 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 103 2e-21 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 102 3e-21 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 102 5e-21 gi|50345997 E1A binding protein p300 [Homo sapiens] 101 7e-21 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 101 9e-21 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 100 1e-20 gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 100 1e-20 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 97 1e-19 gi|56549696 E1A binding protein p400 [Homo sapiens] 97 2e-19 gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 97 2e-19 gi|38158015 mastermind-like 3 [Homo sapiens] 96 4e-19 gi|116284392 mucin 2 precursor [Homo sapiens] 95 8e-19 gi|91982772 mucin 17 [Homo sapiens] 93 3e-18 gi|33286444 mastermind-like 2 [Homo sapiens] 91 9e-18 gi|150170670 piccolo isoform 2 [Homo sapiens] 88 1e-16 gi|150378539 piccolo isoform 1 [Homo sapiens] 88 1e-16 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 87 2e-16 gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 86 3e-16 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 85 6e-16 gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 84 1e-15 gi|47132519 Ras association and pleckstrin homology domains 1 is... 83 2e-15 gi|119943102 CREB binding protein isoform b [Homo sapiens] 82 4e-15 gi|119943104 CREB binding protein isoform a [Homo sapiens] 82 4e-15 gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] 82 4e-15 gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 82 5e-15 gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ... 82 7e-15 gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [... 82 7e-15 >gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] Length = 2063 Score = 4147 bits (10756), Expect = 0.0 Identities = 2063/2063 (100%), Positives = 2063/2063 (100%) Query: 1 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 60 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD Sbjct: 1 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 60 Query: 61 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 120 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR Sbjct: 61 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 120 Query: 121 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA 180 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA Sbjct: 121 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA 180 Query: 181 TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH 240 TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH Sbjct: 181 TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH 240 Query: 241 HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ 300 HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ Sbjct: 241 HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ 300 Query: 301 GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR 360 GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR Sbjct: 301 GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR 360 Query: 361 PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ 420 PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ Sbjct: 361 PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ 420 Query: 421 PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV 480 PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV Sbjct: 421 PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV 480 Query: 481 QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT 540 QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT Sbjct: 481 QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT 540 Query: 541 PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSG 600 PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSG Sbjct: 541 PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSG 600 Query: 601 VPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQ 660 VPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQ Sbjct: 601 VPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQ 660 Query: 661 MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ 720 MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ Sbjct: 661 MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ 720 Query: 721 MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQV 780 MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQV Sbjct: 721 MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQV 780 Query: 781 MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNS 840 MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNS Sbjct: 781 MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNS 840 Query: 841 ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHF 900 ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHF Sbjct: 841 ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHF 900 Query: 901 GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSG 960 GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSG Sbjct: 901 GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSG 960 Query: 961 PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ 1020 PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ Sbjct: 961 PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ 1020 Query: 1021 PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMV 1080 PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMV Sbjct: 1021 PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMV 1080 Query: 1081 SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA 1140 SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA Sbjct: 1081 SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA 1140 Query: 1141 PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV 1200 PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV Sbjct: 1141 PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV 1200 Query: 1201 AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL 1260 AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL Sbjct: 1201 AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL 1260 Query: 1261 PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA 1320 PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA Sbjct: 1261 PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA 1320 Query: 1321 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP 1380 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP Sbjct: 1321 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP 1380 Query: 1381 LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE 1440 LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE Sbjct: 1381 LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE 1440 Query: 1441 LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGA 1500 LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGA Sbjct: 1441 LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGA 1500 Query: 1501 PNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLV 1560 PNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLV Sbjct: 1501 PNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLV 1560 Query: 1561 HPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL 1620 HPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL Sbjct: 1561 HPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL 1620 Query: 1621 QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA 1680 QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA Sbjct: 1621 QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA 1680 Query: 1681 APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATP 1740 APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATP Sbjct: 1681 APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATP 1740 Query: 1741 VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNS 1800 VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNS Sbjct: 1741 VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNS 1800 Query: 1801 PGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT 1860 PGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT Sbjct: 1801 PGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT 1860 Query: 1861 APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT 1920 APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT Sbjct: 1861 APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT 1920 Query: 1921 LVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTAL 1980 LVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTAL Sbjct: 1921 LVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTAL 1980 Query: 1981 QASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSR 2040 QASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSR Sbjct: 1981 QASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSR 2040 Query: 2041 PASASSSTKDITSAVQSKRRKSK 2063 PASASSSTKDITSAVQSKRRKSK Sbjct: 2041 PASASSSTKDITSAVQSKRRKSK 2063 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 118 bits (295), Expect = 7e-26 Identities = 393/1683 (23%), Positives = 588/1683 (34%), Gaps = 344/1683 (20%) Query: 250 RQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQ---QLQARPPQQHQQQQPQGIRPQF 306 R+ A+ +L+ +QQ + Q+Q Q ++QQ++ + R QQ QQQQ Q + Q Sbjct: 3554 REFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQH 3613 Query: 307 TA-----PTQVP----VPPGWNQLPSGALQPP--PAQGSLGTMTANQGWKKAPLPGPMQQ 355 +A P+Q P PG LP LQPP P G G + G LPG Sbjct: 3614 SAVLALSPSQSPRLLTKLPG-QLLPGHGLQPPQGPPGGQAGGLRLTPG--GMALPG---- 3666 Query: 356 QLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNP-GQFTAPQMKSLQGGPS-- 412 P P QQ Q ++ P G F + GP Sbjct: 3667 ------------QPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSR 3714 Query: 413 -----RVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQN---NPLP 464 ++ Q+ L K QQ + Q QQQ GP N P P Sbjct: 3715 LLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQ-QQQQGPGVQTNQALGPKP 3773 Query: 465 QGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQA 524 QG P S G +VQQ + QPP QGPQ + LG + G Sbjct: 3774 QGLMPPSSHQGL--LVQQ---------LSPQPP-QGPQGM---LGPAQVAVLQQQHPGAL 3818 Query: 525 NPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSL 584 P QV T + +PQL A Q G + Q Q Q H Sbjct: 3819 GPQGPHRQVLMTQSRV---LSSPQL-AQQGQGLMGHRLVTAQQQQQQQQH---------- 3864 Query: 585 MGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNP 644 QQ +G+ + S M Q +Q MG QQ+ Q Q +QQQ L Sbjct: 3865 --------QQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQL--QQQQQLQQQQQLQQ 3914 Query: 645 QNPMILSRAQLMPQGQMMVNPPSQNL-GPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQG 703 Q L + Q + Q Q+ Q L Q++ +Q L QQ Q Q Q Sbjct: 3915 QQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQ 3974 Query: 704 QVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPG-PAQ-IMRGPTPNMQGNMVQFTGQ 761 LL Q+ +++ Q Q Q Q + PG PA+ + +P G + TG+ Sbjct: 3975 MGLLNQS---RTLLSPQQQ-------QQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGK 4024 Query: 762 MSGQMLPQ-QGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGD--PATTANNDVSLSQMM 818 + P PS QG L MA + G+ P+ + ++ + L Q Sbjct: 4025 EQNTVDPAVSSEATEGPST---HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQ 4081 Query: 819 PDVSIQQTNMVPP-HVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVN 877 P + PP + Q S H +G G + Q+ G + Sbjct: 4082 PQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGG-----------SHGQLGSGSS------ 4124 Query: 878 KDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRP 937 + S + L Q +S G + QN +P ++P + +T P Sbjct: 4125 ---SEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQN-----------NTGP 4170 Query: 938 AGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPP 997 QPP PG + SG LP P + Q+ QL +A Sbjct: 4171 -------QPPKPGP----VLQSGQGLPGVGIMP-----------TVGQLRAQLQGVLAKN 4208 Query: 998 PQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVS--QNVH 1055 PQ PQ QQQQ Q Q+Q QQ Q + Q+P + P+ Sbjct: 4209 PQLRHLSPQ----QQQQ----LQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQ 4260 Query: 1056 PPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQ 1115 P G P Q P+Q+ G+ P QGP +P P G+ S V Sbjct: 4261 PQLGGF-PGPQTGPLQELGAGP---RPQGPPRLPAPP-------------GALSTGPVL- 4302 Query: 1116 ESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSA 1175 P +P+ P +P P P+ +PS P +QL P + L Sbjct: 4303 -GPVHPTPPP-------------SSPQEPKRPSQLPS----PSSQL------PTEAQLPP 4338 Query: 1176 TQGATPQ-QPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEP 1234 T TP+ Q P P P +P T P+ P P+N + +P Sbjct: 4339 THPGTPKPQGPTLEPP-------PGRVSPAAAQLADTLFSKGLGPWDP--PDNLAETQKP 4389 Query: 1235 SEISLSPERLNASIAGLFP--PQINIPLPPRPN---LNRGFDQQGLNPTTLKAIGQAPSN 1289 + SL P L+ + P Q++I PR L ++ N + A G + Sbjct: 4390 EQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHL 4449 Query: 1290 LTMNPSNFA----TPQTHKLDSVVVNSGKQSN--------------SGATKRASPSNSRR 1331 L P + A + + +V +++G+ S +G ++ + S + Sbjct: 4450 LLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNK 4509 Query: 1332 SSPGSSRKTTPSPGRQNSKAPKLTLAS---------QTNAALLQNVELPRNVLVSPTPLA 1382 + + TP P R + +L + + + ALL+ ++ ++L PL Sbjct: 4510 EDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLL----PLT 4565 Query: 1383 NPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQ---NSQSRKEQVNI 1439 P + +F SL P S C SQ R + Sbjct: 4566 EPAITANF---------------------------SLFAPFGSGCPVNGQSQLRGAFGSG 4598 Query: 1440 ELKAVPAQEVKMVVPEDQSKKDGQPSD--PNKLPSVEENK-NLVSPA--MREAPTSLSQL 1494 L P +++ + S PS P PSV++ N V+P+ + E P + Sbjct: 4599 ALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASA 4658 Query: 1495 LDNSGAPNVT--IKPPGLTDLEVTPPVVSGEDLKKA---------SVIPTLQDLSSSKEP 1543 D+ A T +K L TPP ED++ S++P +SS E Sbjct: 4659 RDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVP-----ASSPES 4713 Query: 1544 SNSLNLPHSNELCSSLVHPELSEVSSNVAPSIP----PVM--SRPVSSSSISTP--LPPN 1595 P L S E S V P IP PV ++P + + P LP Sbjct: 4714 ILGEEAPRFPHLGSGRWEQE-DRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLP-- 4770 Query: 1596 QITVFV--TSNPITTSANTSAALPTHLQSALMSTV----VTMPNAGSKVMVSEGQSAAQS 1649 +T + + ++ SAA +L +++ + +PN+ +V+ E S A++ Sbjct: 4771 -VTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNS-YEVLFPE--SPARA 4826 Query: 1650 NARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFS 1709 P+ + ++G P T P ++ L P + L I +K Sbjct: 4827 GTEPK--KGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVL--PGYTLKSQLDILSLLKQE 4882 Query: 1710 S-APVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNP 1768 S AP PP S + + R L A P + PSPP + P+ PP + + EL P Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQL----SAPPPEEPSPPPSPLAPSPASPPTEPLVEL-P 4937 Query: 1769 DE--ASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQI 1826 E A P V + LP + S P P G P K KG K ++ Sbjct: 4938 TEPLAEPPV-----PSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGVRWKRLRL 4992 Query: 1827 LLT 1829 LLT Sbjct: 4993 LLT 4995 Score = 106 bits (265), Expect = 2e-22 Identities = 288/1282 (22%), Positives = 451/1282 (35%), Gaps = 215/1282 (16%) Query: 79 ESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSVQIEGEGAINLA 138 ++ KLK+ + + + ++ E ++A+ N+Q + Q + A+ LA Sbjct: 3560 DAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAV-LA 3618 Query: 139 LAQNRSQDV--RMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMA 196 L+ ++S + ++ G + G+ ++ G P G+ + PGG M Sbjct: 3619 LSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGL---------RLTPGG-----MAL 3664 Query: 197 PGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVN-RQMNPA 255 PG QP P ++ L+ QQ S +GSLA P P ++ R + P Sbjct: 3665 PG-----QPGGP-------FLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPD 3712 Query: 256 NF----PQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRP-QFTAP- 309 + QLQ QQQ+ Q Q+ QQQQQQQQQQQ L + Q QQQQ G++ Q P Sbjct: 3713 SRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPK 3772 Query: 310 TQVPVPPGWNQ-LPSGALQPPPAQGSLGTM-TANQGWKKAPLPGPMQQQLQARPSLATVQ 367 Q +PP +Q L L P P QG G + A + PG + Q R L T Sbjct: 3773 PQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQS 3832 Query: 368 TPSHPPPPYPFG----------SQQASQAHTNFPQMSNPGQFTAPQ-MKSLQGGPSRVPT 416 P G +QQ Q + Q S G Q + S G P Sbjct: 3833 RVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQ 3892 Query: 417 PL-QQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG 475 P+ L + QQ Q QQQ + Q L Q QQ + Sbjct: 3893 PMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQ 3952 Query: 476 RNPMVQQGNVPPNFMVMQQQ--------------PPNQGPQSLHPGLGGMPKRLPPGFSA 521 + QQ F QQQ P Q Q + G G K L S Sbjct: 3953 QQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSP 4012 Query: 522 GQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQ 581 G P + T +S A + + G G M P ++ Sbjct: 4013 GALGPTLLLTGKEQNTVDPAVSSEATE---GPSTHQGGPLAIGTTPESMATE---PGEVK 4066 Query: 582 PSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVP--------SQG 633 PSL G ++Q PQ S++Q Q PP +L G QQ V S G Sbjct: 4067 PSLSG-----DSQLLLVQPQPQPQPSSLQLQ----PPLRLPGQQQQQVSLLHTAGGGSHG 4117 Query: 634 Q--------------MVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTP 679 Q ++ Q P +++ L PQ M+ P N GP P + P Sbjct: 4118 QLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGP 4177 Query: 680 PKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNK----QQFNTQNQSN 735 Q + P + Q Q +L +NP + + Q Q + Q+ Q+Q+ Sbjct: 4178 VLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAV 4237 Query: 736 VMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGI----QG--QVLR 789 P Q T +QG ++ Q+ G PQ GP+ Q +G QG ++ Sbjct: 4238 RQTPPYQEPGTQTSPLQG-LLGCQPQLGGFPGPQTGPL-----QELGAGPRPQGPPRLPA 4291 Query: 790 PPG---PSPHMAQQHGDPATTANNDVSLSQMMPDVSIQ---QTNMVPPHVQAMQGNSASG 843 PPG P + H P ++ + +P S Q + + P H + + Sbjct: 4292 PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTL 4351 Query: 844 NHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVN 903 G +P + S G P P + P QS + GH Sbjct: 4352 EPPPGR----VSPAAAQLADTLFSKGLGPWDPPDNLAETQKP-----EQSSLVPGHLDQV 4402 Query: 904 NKQNNTNANKPKKKKPPR-----------KKKNSQQDLNTPDT----------RPAG--- 939 N Q A++ K+ PR K++ + + + P T AG Sbjct: 4403 NGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLL 4462 Query: 940 ---LEEADQPPLP---GEQGINLDNSG---PKLPEFSNRPPGYPSQPVEQRPLQQMPPQL 990 L A L G +G+ + +G KL + G PS + + + P+ Sbjct: 4463 LQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPK- 4521 Query: 991 MQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPV 1050 P+ Q+ + +++ ++ + +Q + + L+ +P + Sbjct: 4522 -------PKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEP---AITA 4571 Query: 1051 SQNVHPPRG---PLNPDSQRMPMQQSGSVPV------MVSLQGPASVPPSPDKQRMPMPV 1101 + ++ P G P+N SQ SG++P + + S PP+P P Sbjct: 4572 NFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPP--- 4628 Query: 1102 NTPLGSNSRKMVYQESP-----QNPSSSPLAEMASLPEASGSEAPS------VPGGPNNM 1150 TP S +KMV +P ++P + A + SE S +P P+N Sbjct: 4629 -TPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQ 4687 Query: 1151 PSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAP--TQTSR 1208 V M + SP S ++P+ S+ FP++ + Q R Sbjct: 4688 TEDV-------RMESDEDSDSPDSIVPASSPE-----SILGEEAPRFPHLGSGRWEQEDR 4735 Query: 1209 PKTP-NRASPRPYYPQTPNNRP 1229 +P PR P P+ +P Sbjct: 4736 ALSPVIPLIPRASIPVFPDTKP 4757 Score = 84.0 bits (206), Expect = 1e-15 Identities = 185/826 (22%), Positives = 287/826 (34%), Gaps = 139/826 (16%) Query: 931 NTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRP---PGYPSQPVEQRPLQQMP 987 +TP P L A Q G ++ P + +P G +P + PL + Sbjct: 379 DTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEM 438 Query: 988 PQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ----PQSQQQQQQQQQMMMMLMMQQDP 1043 P L PPP+ P P+ PP S+ P+ + + + +++ P Sbjct: 439 PLL-----PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESP 493 Query: 1044 KSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNT 1103 S P PL+P + P P L P PPSP + P++ Sbjct: 494 LS--------PPPEESPLSPPPESSPFSPLEESP----LSPPEESPPSP---ALETPLSP 538 Query: 1104 PLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMM 1163 P ++ ++ESP +P LP + EA + P P Sbjct: 539 PPEASPLSPPFEESPLSPPPE------ELPTSPPPEASRLSPPPEESP------------ 580 Query: 1164 TGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQ 1223 P P SP+S A+ PP P S ++ P + SR P SP Sbjct: 581 MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPM----S 636 Query: 1224 TPNNRPPSTEPSEIS-LSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKA 1282 P P + P E+S LSP + ++ L PP PL P P + P Sbjct: 637 PPPEESPMSPPPEVSRLSPLPV---VSRLSPPPEESPLSPPPE-----ESPTSPPPEASR 688 Query: 1283 IGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTP 1342 + P + +P +P + + +++ + + P RS G P Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSE-GPHLSPRP 747 Query: 1343 SPGRQNSKAPKLTLASQTNAA-LLQNVELPRNVLVSPTPLANPPVPGSF----PNNSGLN 1397 + + + L+ Q L E P V P +P G P L+ Sbjct: 748 EEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLS 807 Query: 1398 PQNSTVSVAAVGG---VVEDNKESLNVPQDSD-CQNSQSRKEQVNIELKAVPAQEVKMVV 1453 PQ ++ V + +ES PQ + C + + + ++ EL+ P Sbjct: 808 PQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPL------- 860 Query: 1454 PEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDL 1513 + + P +P + P+ EE P SLS LL G P + PG Sbjct: 861 ---SPRPEKPPEEPGQCPAPEELPLFPPP----GEPSLSPLL---GEP--ALSEPG---- 904 Query: 1514 EVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVA- 1572 PP+ S +P LS S EPS S L + L P LS + + A Sbjct: 905 --EPPL---------SPLPEELPLSPSGEPSLSPQLMPPDPL-----PPPLSPIITAAAP 948 Query: 1573 PSIPPV--MSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVT 1630 P++ P+ + P + S P P + T AN + P + ++ Sbjct: 949 PALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEP-------VPPMIL 1001 Query: 1631 MPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQ---VMKGSQPS--TIPAAPLTT 1685 P+ GS V A P + P+ S ++Q V + S PS + PA PL+ Sbjct: 1002 PPSPGSPV----------GPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSV 1051 Query: 1686 NSGLMP----PSVAVVGPLHIPQNIKFSSAPVP---PNALSSSPAP 1724 S L P V+ LH + K S P P+A S P+P Sbjct: 1052 PSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSP 1097 Score = 72.0 bits (175), Expect = 6e-12 Identities = 152/718 (21%), Positives = 250/718 (34%), Gaps = 106/718 (14%) Query: 930 LNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQ 989 L P+ P + P P + L +LP + S+P+E+ PL P + Sbjct: 441 LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE 500 Query: 990 LMQHVAPPPQPPQQQP------QPQLPQQQQPPPPS-------QPQSQQQQQQQQQMMMM 1036 +P PP+ P P P ++ PP P+ P++ ++ + Sbjct: 501 -----SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLS 555 Query: 1037 LMMQQDPKSVRLPVSQNVHPP-RGPLNPDSQRMPMQQSGSVPVMVS--LQGPASVPPS-- 1091 ++ P S S+ PP P++P + PM + + P S PP Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615 Query: 1092 -----PDKQRM-PMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASL---PEASGSEAPS 1142 P+ R+ P P ++P+ + P+ SPL ++ L PE S P Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP- 674 Query: 1143 VPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPP----VNSLPSSHGHHFP 1198 P P+ P + P P SP S +P PP + SLP P Sbjct: 675 ----PEESPTS---PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP 727 Query: 1199 NVAAPTQTSRPKTPNRASPRPYYPQ-TPNNRPPSTEP--SEISLSPERLNASIAGLFPPQ 1255 P R + P+ SPRP P +P P P E LSP+ + + Sbjct: 728 LPEEPQLCPRSEGPH-LSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP 786 Query: 1256 INIPLPPRPNLNRGFDQQGLNPTT----LKAIGQAPSNLTMNPSNFATPQTHKLDSVVVN 1311 P P+L+ ++ L+P T L + + P + +PQ+ + + Sbjct: 787 HLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE--EPCLSP 844 Query: 1312 SGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGR--------QNSKAPKLTLASQTNAA 1363 ++S+ P + R P P+P + S +P L + + Sbjct: 845 RPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPG 904 Query: 1364 LLQNVELPRNVLVSPT--PLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNV 1421 LP + +SP+ P +P + P L+P + + A+ + E + Sbjct: 905 EPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGE-LEYPFGA 963 Query: 1422 PQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVS 1481 DSD ++ A P E + P + + D +P P LP + V Sbjct: 964 KGDSDPESP-----------LAAPILETPISPPPEANCTDPEPVPPMILPPSPGSP--VG 1010 Query: 1482 PA----MREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDL 1537 PA M P S LL +S P + PP + +PP + S I + + Sbjct: 1011 PASPILMEPLPPQCSPLLQHSLVPQNS--PPS----QCSPPALPLSVPSPLSPIGKVVGV 1064 Query: 1538 SSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSS--SSISTPLP 1593 S E L E +VS P++ P + P+ S +S P P Sbjct: 1065 SDEAE----------------LHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAP 1106 Score = 57.0 bits (136), Expect = 2e-07 Identities = 123/502 (24%), Positives = 175/502 (34%), Gaps = 81/502 (16%) Query: 929 DLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPP 988 +L TPD A L P G+ L P P P PS P RP P Sbjct: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP--PPAQALAPSPPSHPDIFRPGSYTDP 2377 Query: 989 QLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ--PQSQQQQQQQQQMMMMLMMQQDPKSV 1046 + P PQPP + LP + P P P S Q Q Q P + Sbjct: 2378 YAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSS----------SQSPLTP 2427 Query: 1047 RLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPM-PVNTPL 1105 R P+S P P+ P Q P S PPS + R P P++ P Sbjct: 2428 R-PLSAEAFCP-SPVTPRFQS---------------PDPYSRPPSRPQSRDPFAPLHKPP 2470 Query: 1106 GSNSRKMVYQE-SPQNPSSSPLAEMASLPEASGSEA-PSVPGGPNNMPSHVVLPQNQLMM 1163 ++ ++ S + S A+LP E VP G P+ V P + Sbjct: 2471 RPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSG--QPPNFVRSPGTGAFV 2528 Query: 1164 TGPKPGPSPLSATQGATPQQPPV--NSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYY 1221 P P G +PPV LP HG + PT +P++ N Y Sbjct: 2529 GTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPT-LGKPQSTN-------Y 2580 Query: 1222 PQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPP---RPNLNRGFDQQG---- 1274 N PS P S + ++ L PP + P P P L+ G Q+ Sbjct: 2581 TVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITS 2640 Query: 1275 -----LNPTTLKAIGQAPSNL--TMNPSNFATPQT--------HKLDSVVVNSGKQSNSG 1319 +P T A + L T +P QT +L +++ Q N+ Sbjct: 2641 PVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTL 2700 Query: 1320 ATKR--ASPSNSRRSSPGSSRKTTPSPG-RQNSKAPKLTLASQTNAALLQNVELPRNVLV 1376 ++ A+ + PGS SP Q S+ +Q ++L V LP Sbjct: 2701 RQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSL---VGLP----- 2752 Query: 1377 SPTPLANPPV-PGSFPNNSGLN 1397 P+ L+ P + PGSFP++ L+ Sbjct: 2753 -PSKLSGPILGPGSFPSDDRLS 2773 Score = 54.3 bits (129), Expect = 1e-06 Identities = 176/916 (19%), Positives = 290/916 (31%), Gaps = 129/916 (14%) Query: 372 PPPPYPFGSQQASQAHTNF-PQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPAS 430 PP P GS + A T F + P + L+ VP P L K P Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166 Query: 431 SPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV---------Q 481 P+ P + + PP P P P +P + PM+ Q Sbjct: 2167 VPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPS----PTGAPAQPPMLGASSRPGAGQ 2222 Query: 482 QGN---VPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTA 538 G PP Q P+ + P L + PG G+A+ + + Sbjct: 2223 PGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLL--------S 2274 Query: 539 TTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGT 598 P L+ + GA P S+GPPN+ ++ + T Sbjct: 2275 PPPFGESRKALEVKKEEL-----GASSP------SYGPPNLGFVDSPSSGTHLGGLELKT 2323 Query: 599 SGVPQVNLSNMQGQ-----------PQQGPPSQLMGMHQQIVPS-------QGQMVQQQG 640 V + L+ Q PQ+ PP+Q + P Q Sbjct: 2324 PDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL 2383 Query: 641 TLNPQNPMILSRAQLMPQG-------QMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMA 693 T PQ P S L P+ ++ +P SQ+ SP +TP P + Sbjct: 2384 TPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSP--LTPRPLSAEAFCPSPVT 2441 Query: 694 PHNQMMGPQGQVLLQ---QNPMIEQIMTNQMQGNKQQFNTQNQSNVMPG----PAQIMRG 746 P Q P + + ++P + Q + F + ++ G PA + G Sbjct: 2442 PRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAG 2501 Query: 747 PTPNMQG--------NMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMA 798 P + N V+ G +G + P+ + Q +G L+PP P P + Sbjct: 2502 PAGELHAKVPSGQPPNFVRSPG--TGAFVGTPSPMRFTFPQAVGEPS--LKPPVPQPGLP 2557 Query: 799 QQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFS 858 HG + + ++ N H +SG+ +G+S P S Sbjct: 2558 PPHGINSHFGPGPTLGKPQSTNYTVATGNF---HPSGSPLGPSSGSTGESYGLSPLRPPS 2614 Query: 859 ----GAPNGN----QMSCGQNPGF--PVNK----DVTLTSPLLVNLLQSDISAGHFGVNN 904 AP+G+ Q G PV K + S L L G G++ Sbjct: 2615 VLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQ 2674 Query: 905 KQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLP 964 + + + ++ +++ + L A A PP G G + S P Sbjct: 2675 TELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPP--GSWGA--EPSSPAFE 2730 Query: 965 EFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQ 1024 + S + + + P +L + P P + +PPPP+ P S Sbjct: 2731 QLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDD------RLSRPPPPATPSSM 2784 Query: 1025 QQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQG 1084 +Q Q+ P +P PL Q++ QQ + + Sbjct: 2785 DVNSRQLVGGSQAFYQRAP-----------YPGSLPLQQQQQQLWQQQQATAATSMRFAM 2833 Query: 1085 PASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSP---LAEMASLPEASGSEAP 1141 A P +P + + +PL S ++ P + P + ++ + G Sbjct: 2834 SARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGT 2893 Query: 1142 SVPG-GPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHG--HHFP 1198 PG GP P + ++ + P A G PQ+P P + H P Sbjct: 2894 PFPGQGPPQRPRFYPVSEDPHRLA---PEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTP 2950 Query: 1199 NVAAPTQTSRPKTPNR 1214 + PT + + NR Sbjct: 2951 HTKGPTLPTGLELVNR 2966 Score = 53.9 bits (128), Expect = 2e-06 Identities = 166/724 (22%), Positives = 245/724 (33%), Gaps = 166/724 (22%) Query: 185 PPGGNVSSSMMAPGPNP------ELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAP 238 PP G+V PGP+ +L P+ P +Q + DP GL P AP Sbjct: 2145 PPAGSV------PGPDSPGELFLKLPPQVP---AQVPSQDPF--GLAPAYPLEPRFPTAP 2193 Query: 239 PHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPP--QQHQQ 296 P +P P PA P L + Q + PP +HQ Sbjct: 2194 PTYPPYPSPTGA---PAQPPMLGASSRPGAGQPGE------------FHTTPPGTPRHQP 2238 Query: 297 QQPQG-IRPQFTAPTQVPVPP----GWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPG 351 P ++P+ + + VP G + L PPP G Sbjct: 2239 STPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPF-------------------G 2279 Query: 352 PMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAP------QMK 405 ++ L+ + +PS+ PP F +S H ++ P F AP Q++ Sbjct: 2280 ESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVE 2339 Query: 406 SLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGS---PASSPTVNQTQQQMGPR-----P 457 G P SP S P F+ GS P + P + Q P P Sbjct: 2340 PQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALP 2399 Query: 458 PQNNPLPQGFQQPVS----SPGRNPMVQQ---------GNVPPNFMVMQ--QQPPNQGPQ 502 P++ P + P S S ++P+ + V P F +PP++ PQ Sbjct: 2400 PRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR-PQ 2458 Query: 503 SLHP--GLGGMPKRLPP--GFSAGQ-ANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQH 557 S P L P+ PP F AG A+ + G P+ P ++ + Q Sbjct: 2459 SRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNF 2518 Query: 558 AGGQGAGP------------PQNQMQVSHGPPNMMQPSLMGIHG-NMNNQQAGTSGVPQ- 603 G G PQ + S PP + QP L HG N + T G PQ Sbjct: 2519 VRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPP-VPQPGLPPPHGINSHFGPGPTLGKPQS 2577 Query: 604 VNLSNMQG--QPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQM 661 N + G P P + PS G + G + P +L P G + Sbjct: 2578 TNYTVATGNFHPSGSP----------LGPSSGSTGESYGLSPLRPPSVLPPP--APDGSL 2625 Query: 662 --MVNPPSQNLG---PSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQG------QVLLQQN 710 + + SQ G P +R P M S + P Q G G + Q+ Sbjct: 2626 PYLSHGASQRSGITSPVEKREDPGTGMGSSLATAEL-PGTQDPGMSGLSQTELEKQRQRQ 2684 Query: 711 PMIEQIMTNQMQGN--KQQFNTQNQSNVMPGP-------------AQIMRGPTPNMQGNM 755 + E ++ Q+Q N +Q+ T + GP Q+ RG TP Sbjct: 2685 RLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTP------ 2738 Query: 756 VQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPG-PSPHMAQQHGDPATTANNDVSL 814 F G L V PS+ + G +L P PS + PAT ++ DV+ Sbjct: 2739 --FAGTQDKSSL-----VGLPPSK---LSGPILGPGSFPSDDRLSRPPPPATPSSMDVNS 2788 Query: 815 SQMM 818 Q++ Sbjct: 2789 RQLV 2792 Score = 50.4 bits (119), Expect = 2e-05 Identities = 146/738 (19%), Positives = 245/738 (33%), Gaps = 100/738 (13%) Query: 199 PNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFP 258 P PE P +P P + P S L + P+ L H +P+ + P Sbjct: 442 PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEES 501 Query: 259 QLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGW 318 L + ++ ++ A + + P F + P+ P Sbjct: 502 PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF---EESPLSPPP 558 Query: 319 NQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQA-RPSLATVQTPSHPPPPYP 377 +LP+ PPP L P PM +A R ++P PPP Sbjct: 559 EELPT---SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615 Query: 378 FGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQ 437 S + + P +P + P +S P V P ++ SP S Sbjct: 616 PLSPPPEASRLSPPPEDSP--MSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673 Query: 438 GSPASSPTVNQTQQQMGPRPPQNNPL-PQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQP 496 P SPT + PP+++P P P S P + ++ + + ++P Sbjct: 674 -PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732 Query: 497 --------PNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQG-------QVPSTTATTP 541 P+ P+ P L P+ P S P+ VP +P Sbjct: 733 QLCPRSEGPHLSPRPEEPHLSPRPEE--PHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP 790 Query: 542 GNSGAPQLQANQNVQHAGGQGAGP-----PQN-----QMQVSHGPPNMMQPSLMGIHGNM 591 G P L H Q P P+ Q + SH P +P L + Sbjct: 791 QAEG-PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCL-----SP 844 Query: 592 NNQQAGTSGVPQVNLSNMQGQPQQGP--------PSQLMGMHQQIVPSQGQMVQQQGTLN 643 +++ S P++ + +P++ P P +L PS ++ + Sbjct: 845 RPEESHLS--PELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902 Query: 644 PQNPMIL---SRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMG 700 P P + L P G+ ++P P P ++P +++ P ++P ++ Sbjct: 903 PGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP---IITAAAPPALSPLGELEY 959 Query: 701 PQGQV--LLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMP-----------GPAQ-IMRG 746 P G ++P+ I+ + + N + V P GPA I+ Sbjct: 960 PFGAKGDSDPESPLAAPILETPI-SPPPEANCTDPEPVPPMILPPSPGSPVGPASPILME 1018 Query: 747 PTPNMQGNMVQFT--------GQMSGQMLPQQGPVNNSP-SQVMGIQGQVLRPPGPSPHM 797 P P ++Q + Q S LP P SP +V+G+ + + + Sbjct: 1019 PLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKV 1078 Query: 798 AQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPF 857 ++ PA + L M D+S + P + + FSG G AP Sbjct: 1079 SEPE-CPALEPSATSPLPSPMGDLSCPAPSPAP-----------ALDDFSGLGED-TAPL 1125 Query: 858 SG--APNGNQMSCGQNPG 873 G AP G+Q GQ PG Sbjct: 1126 DGIDAP-GSQPEPGQTPG 1142 Score = 48.5 bits (114), Expect = 7e-05 Identities = 94/431 (21%), Positives = 154/431 (35%), Gaps = 64/431 (14%) Query: 1372 RNVLVSPTPLAN---PPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNV--PQDSD 1426 R+V TP+ + PP PG P + + + VA G + S+ P Sbjct: 359 RSVAEQHTPVCSRFSPPEPGDTPTD-----EPDALYVACQGQPKGGHVTSMQPKEPGPLQ 413 Query: 1427 CQNSQSRKEQVNIE--LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAM 1484 C+ K V +E L+A +E+ ++ P ++S P + P E ++ +SP Sbjct: 414 CEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASR--LSPPP 471 Query: 1485 REAPTS-------LSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDL 1537 E P S LS+ L+ S PP + L P L+++ + P Sbjct: 472 EELPASPLPEALHLSRPLEESPLS----PPPEESPLSPPPESSPFSPLEESPLSPP---- 523 Query: 1538 SSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQI 1597 PS +L P S +S + P E + P P S P +S +S P + + Sbjct: 524 -EESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPT-SPPPEASRLSPPPEESPM 581 Query: 1598 TVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFIT 1657 + +P++ S P +S L P +S A++ + P+ + Sbjct: 582 SPPPEESPMSPPPEASRLFPPFEESPLSPPPEESP-------LSPPPEASRLSPPPED-S 633 Query: 1658 PVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNA 1717 P+ P P +P PP V+ + PL + + PP Sbjct: 634 PM------------SPPPEESPMSP--------PPEVSRLSPLPVVSRLS-----PPPEE 668 Query: 1718 LSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNT 1777 SP P P +SR +P SP P+ PP + P E SP + Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL 728 Query: 1778 SADQNTLPSSQ 1788 + P S+ Sbjct: 729 PEEPQLCPRSE 739 Score = 39.7 bits (91), Expect = 0.031 Identities = 86/379 (22%), Positives = 133/379 (35%), Gaps = 66/379 (17%) Query: 185 PPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQ 244 P G + S+ + G +P L+P + P D P LS S SG +P Sbjct: 2593 PLGPSSGSTGESYGLSP-LRPPSVLPPPAPDGSLPYLS----HGASQRSGITSPVEKRED 2647 Query: 245 P-VSVNRQMNPANFPQLQQQ-----QQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQ 298 P + + A P Q Q + ++Q+Q+Q+ ++ +QQ+Q +Q ++ Sbjct: 2648 PGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETA 2707 Query: 299 PQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGS---LGTMTANQ--GWKKAPLPGPM 353 A V P W PS ++G GT + G + L GP Sbjct: 2708 A-------AAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGP- 2759 Query: 354 QQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQF---TAPQMKSLQGG 410 + S + S PPPP S N Q+ Q AP Sbjct: 2760 ---ILGPGSFPSDDRLSRPPPP-----ATPSSMDVNSRQLVGGSQAFYQRAPY------- 2804 Query: 411 PSRVPTPLQQPHLTNKSPASSPSSFQQGSPA---SSPTVNQTQQQMG----------PRP 457 P +P QQ L + A++ +S + A S+P +Q +G P P Sbjct: 2805 PGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGP 2864 Query: 458 PQNNPLPQGFQQPVS---------SPGRNPMVQQGNVP-PNFMVMQQQPPNQGPQSLHP- 506 + P P G Q + PG P QG P F + + P P+ L Sbjct: 2865 GEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGL 2924 Query: 507 GLGGMPKRLPPGFSAGQAN 525 + G+P + P A + N Sbjct: 2925 AVSGLPPQKPSAPPAPELN 2943 Score = 39.3 bits (90), Expect = 0.040 Identities = 147/751 (19%), Positives = 249/751 (33%), Gaps = 146/751 (19%) Query: 325 ALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQ--------LQARPSLATV---QTPSHPP 373 A Q P G + +M + PGP+Q + +Q P L + P PP Sbjct: 391 ACQGQPKGGHVTSMQPKE-------PGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPP 443 Query: 374 PPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPS 433 P S ++ T+ P ++ +P + L P +P L +SP S P Sbjct: 444 PEESPLSPPPEESPTSPPPEASR---LSPPPEELPASP--LPEALHLSRPLEESPLSPPP 498 Query: 434 SFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVS--------------SPGRNPM 479 SP + ++ PP+ +P + P+S SP P Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP 558 Query: 480 VQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTAT 539 + PP PP + P S P P PP A + P F + + Sbjct: 559 EELPTSPPPEASRLSPPPEESPMS--PPPEESPMSPPP--EASRLFPPFEESPLSPPPEE 614 Query: 540 TPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMN------- 592 +P +P +A++ PP + +S PP + + S + + ++ Sbjct: 615 SP---LSPPPEASRLSPPPEDSPMSPPPEESPMS-PPPEVSRLSPLPVVSRLSPPPEESP 670 Query: 593 ----NQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPM 648 +++ TS P+ S + P+ P S P + ++ +P P Sbjct: 671 LSPPPEESPTSPPPEA--SRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP- 727 Query: 649 ILSRAQLMPQGQ---MMVNPPSQNLGPSPQ--RMTPPKQ--MLSQQ-------------- 687 + QL P+ + + P +L P P+ ++P + LS Q Sbjct: 728 LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPH 787 Query: 688 -GPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRG 746 PQ PH + PQ + L +P E+ + + +S++ P + Sbjct: 788 LSPQAEGPH---LSPQPEE-LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843 Query: 747 PTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPAT 806 P P + ++ + P++ P P Q + L PP P ++ G+PA Sbjct: 844 PRPE-ESHLSPELEKPPLSPRPEKPP--EEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL 900 Query: 807 TANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQM 866 + + LS + ++ + + Q M + ++ AP + +P G Sbjct: 901 SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPP--LSPIITAAAPPALSPLGEL- 957 Query: 867 SCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNS 926 + P F D SPL +L++ IS PP Sbjct: 958 ---EYP-FGAKGDSDPESPLAAPILETPIS----------------------PP------ 985 Query: 927 QQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQM 986 + N D P + PP PG P P+ P+ PL Sbjct: 986 -PEANCTDPEP--VPPMILPPSPGS-------------------PVGPASPILMEPLPPQ 1023 Query: 987 PPQLMQH-VAPPPQPPQQQPQPQLPQQQQPP 1016 L+QH + P PP Q P LP P Sbjct: 1024 CSPLLQHSLVPQNSPPSQCSPPALPLSVPSP 1054 Score = 37.0 bits (84), Expect = 0.20 Identities = 36/145 (24%), Positives = 59/145 (40%), Gaps = 15/145 (10%) Query: 902 VNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPG-EQGINLDNSG 960 + KQ + +P +++ +++++S P + E P L G +Q ++L +G Sbjct: 3260 LQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAG 3319 Query: 961 PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLM-----------QHVAPPPQPPQQQPQPQL 1009 + P P P+QP Q++ P + QH PQQ QP L Sbjct: 3320 ARQPGLPQ--PLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVL 3377 Query: 1010 PQQQQ-PPPPSQPQSQQQQQQQQQM 1033 Q+ PPS QQ QQQ+ Sbjct: 3378 SQKPMGTMPPSMCMKPQQLAMQQQL 3402 Score = 34.7 bits (78), Expect = 0.99 Identities = 132/635 (20%), Positives = 207/635 (32%), Gaps = 116/635 (18%) Query: 603 QVNLSNMQGQPQQ--------GPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQ 654 Q+ + Q Q QQ GP + H+ PS QQQ +L + +R Sbjct: 3269 QLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGS-QQQLSLG----LAGARQP 3323 Query: 655 LMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIE 714 +PQ M PP+ L QR+ P M+S QG + H G Q ++ QQ Sbjct: 3324 GLPQPLMPTQPPAHAL---QQRLAPSMAMVSNQGHMLSGQH----GGQAGLVPQQ----- 3371 Query: 715 QIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVN 774 + Q +Q MP P+ M+ + Q++ P Sbjct: 3372 ---------SSQPVLSQKPMGTMP--------PSMCMKPQQLAMQQQLANSFFPD----- 3409 Query: 775 NSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQ 834 + + + + P M G A + ++ P ++ QQ +++ + Sbjct: 3410 ---TDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVA---PGMNRQQVSLLAQRLS 3463 Query: 835 AMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQ---NPGFPVNKDVTLTSPLLVNLL 891 + + +G G +A P N + Q N + L + + Sbjct: 3464 GGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQM 3523 Query: 892 QSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGE 951 Q + GV+ K K R K + ++ D L Q + + Sbjct: 3524 QLKVLEEQIGVHRKSRKALCAK------QRTAKKAGREFPEADAEKLKLVTEQQSKIQKQ 3577 Query: 952 QGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQ--PQL 1009 LD + E +N Y ++ +Q+ QQ Q QH A P Q P+ +L Sbjct: 3578 ----LDQVRKQQKEHTNLMAEYRNK--QQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKL 3631 Query: 1010 PQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGP-LNPD-SQR 1067 P Q P QP Q + + P + LP P GP LN +Q+ Sbjct: 3632 PGQLLPGHGLQPPQGPPGGQAGGLRL------TPGGMALP-----GQPGGPFLNTALAQQ 3680 Query: 1068 MPMQQSGSVPVMVSLQGPAS------------VPPSPDKQRMPMPVNTPLGSNSRKMVYQ 1115 Q SG SL GP+ P S Q + + ++K+ Q Sbjct: 3681 QQQQHSGGAG---SLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQ 3737 Query: 1116 ESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKP-GPSPLS 1174 + Q L ++A + + P V NQ + GPKP G P S Sbjct: 3738 QQQQQQQQHLLGQVAI--QQQQQQGPGV-------------QTNQAL--GPKPQGLMPPS 3780 Query: 1175 ATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRP 1209 + QG QQ G P A Q P Sbjct: 3781 SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHP 3815 Score = 32.7 bits (73), Expect = 3.8 Identities = 68/298 (22%), Positives = 95/298 (31%), Gaps = 56/298 (18%) Query: 1672 GSQPSTIPAAPLTTNSGLMPP-SVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGR 1730 GS PLT PP S + P +P + FS P P + SSS +P T R Sbjct: 2372 GSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSD-PFSRVPASPQSQSSSQSP--LTPR 2428 Query: 1731 PL----VLSSRATP--------VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTS 1778 PL S TP + PS P + P P H P + +A +TS Sbjct: 2429 PLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTS 2488 Query: 1779 ADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGS 1838 P++ L P + + P + G + T + + T Sbjct: 2489 LGAGGFPAA---------LPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFP 2539 Query: 1839 LEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTS------- 1891 GE PGL +++ P PTL K S Sbjct: 2540 QAVGEPSLKP---------PVPQPGLPPPHGINSHFG------PGPTLGKPQSTNYTVAT 2584 Query: 1892 -------SPVGPGTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIAS 1942 SP+GP + S G S G P S++ P + + S GI S Sbjct: 2585 GNFHPSGSPLGPSSGSTGESY--GLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITS 2640 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 105 bits (262), Expect = 5e-22 Identities = 219/1018 (21%), Positives = 333/1018 (32%), Gaps = 196/1018 (19%) Query: 870 QNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQD 929 + P P K S + ++ + G+ + A P PP K Sbjct: 898 EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPA-- 955 Query: 930 LNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQ 989 TP + A A PP P GP P P G P+ P P + P Sbjct: 956 --TPSPKWAPTPPAATPPSP--------KGGPATPS----PKGAPTPPAATPPSPKGGPA 1001 Query: 990 LMQHVAPPPQPPQQQPQPQ-------LPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQD 1042 P P P P+ P+ PP + P S + + Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL--------- 1052 Query: 1043 PKSV-RLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPV 1101 PK P + P GP P + P + + P GPA+ PSP MP P Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG--GPAT--PSPKGAPMP-PA 1107 Query: 1102 NTPLGSNSRKMV--YQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQN 1159 TP ++ +P P+++P + L AP+ P PS P+ Sbjct: 1108 ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA--TPPS----PKG 1161 Query: 1160 QLMMTGPKPGPSPLSATQGATPQQP---------------PVNSLPSSHGHHFPNVAAPT 1204 L PK P+ T ATP P P + PS G +A P+ Sbjct: 1162 GLATPPPKGAPT----TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG----GLATPS 1213 Query: 1205 QTSRPKTPNRASPRPYYP-QTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPR 1263 P TP P P TP+ + T P+ SP+ A+ PP P PP Sbjct: 1214 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT-----PPPKGAPTPPA 1268 Query: 1264 ---PNLNRGF----DQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQS 1316 P+L G + NP + T P TP S + G Sbjct: 1269 ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328 Query: 1317 NSGA---------TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQN 1367 GA + + +P+ + TTPS ++ P T + + A+ Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS-SKEGPTPPAATPSHKGGPAMTP- 1386 Query: 1368 VELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDC 1427 P+ P+P +P P P L+P+ + + G +K L P + Sbjct: 1387 -PSPKRGPAIPSPKGDPTSPAVIP----LSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441 Query: 1428 QNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNL-VSPAMRE 1486 ++ A P+ + +P +P P ++ + K +PA Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501 Query: 1487 APTSLSQLLDNSG--------------APNVTI----KPPGLTDLE-VTPPVVSGEDLKK 1527 APT L ++ +S AP T+ P L E + PP ++ KK Sbjct: 1502 APT-LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560 Query: 1528 ASVIPTLQDLS---SSKE--------PSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIP 1576 IPT ++ SSKE PS P EL L+ P ++ S AP+ P Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL---LIPPAVTSPSPKEAPT-P 1616 Query: 1577 PVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGS 1636 P ++ P +TP P TS P+T S+ + PT S T+P A Sbjct: 1617 PAVTPPSPEKGPATPAPKGT----PTSPPVTPSSLKDS--PTSPASVTCKMGATVPQASK 1670 Query: 1637 KVMVSEGQSAAQ------------------------------------------------ 1648 + +G +A + Sbjct: 1671 GLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPL 1730 Query: 1649 SNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKF 1708 S P + PV +SS + S P AP + + + A L P++ Sbjct: 1731 STVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASV 1790 Query: 1709 SSAPVPPNA--LSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSS------PVVPSHP 1758 S+AP PP + L+ SP P + + + SS ++ PS P + P++P P Sbjct: 1791 SAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEP 1848 Score = 103 bits (256), Expect = 2e-21 Identities = 239/1153 (20%), Positives = 363/1153 (31%), Gaps = 219/1153 (18%) Query: 195 MAPGPNP---ELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQ 251 +A P+P + P+T RP ++ + P P G+L+ P P V Sbjct: 790 LADSPSPLGVSVSPQTKRPPTKKGSAGP----------DTPIGNLSSPVSP-----VEAS 834 Query: 252 MNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQ 311 P N Q + PP P + P +P Sbjct: 835 FLPENSLSFQGSKDSPATTHSPT---------------PPSPKGAPTPSAVTP--LSPKG 877 Query: 312 VPVPPGWNQLPS---------GALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPS 362 V +PP PS G P P Q +MT++ K P P + + A PS Sbjct: 878 VTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAP--KGIPASPS 935 Query: 363 LATVQTPSHPPPPYPFGSQQASQAH--TNFPQMSNPGQFTAPQMKSLQGGPS----RVPT 416 TP PP P G P + P P S +G P+ P+ Sbjct: 936 PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS 995 Query: 417 PLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGR 476 P P + A +P + SP SP + P P P+G P Sbjct: 996 PKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055 Query: 477 NPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGM---PKRLPPGFSAGQANPNFMQGQV 533 P +P P GP + P L G P PP G A P+ + Sbjct: 1056 APTTPAATLP---------SPKGGPAT--PSLKGAPTPPAATPPSPKGGPATPSPKGAPM 1104 Query: 534 PSTTA--------TTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLM 585 P TP + GAP A GG PP+ P PS Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP----PSPK 1160 Query: 586 GIHGNMNNQQAGTSGVPQVNLSNMQG------------QPQQGPPSQLMGM------HQQ 627 G G G P + +G P PPS G+ Sbjct: 1161 G--GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1218 Query: 628 IVPSQGQMVQQQGTLNPQ---NPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQML 684 P+ + G P P + P+G PP P+P TPP Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG--APTPPAATPP---- 1272 Query: 685 SQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIM 744 S +G PH P V+ +P + T PG Sbjct: 1273 SLKGGLATPPHKG--APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330 Query: 745 RGPTPNMQGNMVQFTGQMSGQMLPQQGPVN----NSPSQVMGIQ----------GQVLRP 790 PTP V LP P + +PS G G + P Sbjct: 1331 GAPTP----PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386 Query: 791 PGP--SPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSG 848 P P P + GDP + A +S + P + + P + + + Sbjct: 1387 PSPKRGPAIPSPKGDPTSPAVIPLS-PKKAPATPVTREGAATPSKGDLTPPAVTPVSLK- 1444 Query: 849 HGMSFNAPFSGAPNGNQMSCGQNPGFPVNK-DVTLTSPLLVNLLQSDISAGHFGVNNKQN 907 AP + AP G P P +K D TL + Sbjct: 1445 -----KAPATSAPKG-------GPATPSSKGDPTLPA----------------------- 1469 Query: 908 NTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLP--E 965 P K+PP K+ + ++P PA P LP + +S ++P Sbjct: 1470 ---VTPPSPKEPPAPKQVATS--SSPKKAPATPAPMGAPTLPAV----IPSSPKEVPATP 1520 Query: 966 FSNRPPGYPSQPV--EQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQS 1023 S R P P+ + ++ P P + + + P P + P +P ++ P+ P S Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLAPKEAL--IPPAMTVPSPKKTPAIPTPKE--APATPSS 1576 Query: 1024 QQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQ 1083 ++ P +V + P+ L P + P + P Sbjct: 1577 KE--------------ASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP------ 1616 Query: 1084 GPASVPPSPDK-QRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPS 1142 PA PPSP+K P P TP ++SP +P+S A++P+A S+ Sbjct: 1617 -PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA--SKGLP 1673 Query: 1143 VPGGPNNMPSHVV--LPQNQLMMTGP-KPGPSPLSATQGATPQQPPVNSLPSSHGHHFPN 1199 GP + +V P++ ++T P + GP ++ + P P ++ S G Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTV 1733 Query: 1200 VAAP--------TQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGL 1251 AP ++T++ K + + P P P T + + P+ +AS++ Sbjct: 1734 APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAA 1793 Query: 1252 FPPQINIPLPPRP 1264 P +++PL P P Sbjct: 1794 PSPPVSLPLAPSP 1806 Score = 103 bits (256), Expect = 2e-21 Identities = 263/1246 (21%), Positives = 412/1246 (33%), Gaps = 209/1246 (16%) Query: 914 PKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNS----GPKLPEFSNR 969 P+ K+PP KK ++ PDT P G P P E +NS G K + Sbjct: 803 PQTKRPPTKKGSAG-----PDT-PIG--NLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854 Query: 970 PPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQ--------QPQPQLPQQQQPPPPSQP 1021 P PS P P PP + P + P P +Q P S Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914 Query: 1022 QSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRG-PLNPDSQRMPMQQSGSVP--- 1077 S ++ + + PK P + P+G P P + P + + P Sbjct: 915 SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK 974 Query: 1078 ---VMVSLQG----PASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQ-NPSSSPLAEM 1129 S +G PA+ PPSP K P +P G+ + V SP+ +P+++P + Sbjct: 975 GGPATPSPKGAPTPPAATPPSP-KGGPATP--SPKGAPTPPAVTPPSPKGSPAATPFPKG 1031 Query: 1130 ASLPEASGSEAPSVPGGPNNMPSHVVLPQNQ-----LMMTGPKPGPSPLSATQGATPQQP 1184 AS P A+ P P P+ LP+ + PK GP+ S TP Sbjct: 1032 ASTPPAA------TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP--- 1082 Query: 1185 PVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYP-QTPNNRPPSTEPSEISLSPER 1243 P + PS G A P+ P P P P TP ++ T P+ SP+ Sbjct: 1083 PAATPPSPKG----GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138 Query: 1244 LNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTH 1303 A+ P PP P PTT A +P PS P T Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198 Query: 1304 KLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAA 1363 + S G SP + +P + T PSP + P A T AA Sbjct: 1199 A-------ATPPSPKGGLATPSP----KGAPTTPAATPPSP-KGGLATPSPKGAPTTPAA 1246 Query: 1364 LLQNVELPRNVLVSPTPLANP--PVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNV 1421 P+P P P P P P + +A N + Sbjct: 1247 ------------TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294 Query: 1422 PQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVS 1481 P + K P+ + P + G P+ P P Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK----GAPTPPAVTP---------- 1340 Query: 1482 PAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTP-----PVVSGEDLKKASVIPTLQD 1536 P+ + PT + + G P G T TP P ++ K+ IP Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP---- 1396 Query: 1537 LSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQ 1596 S +P++ +P +S AP+ P V ++ S PP Sbjct: 1397 -SPKGDPTSPAVIP----------------LSPKKAPATP-VTREGAATPSKGDLTPPAV 1438 Query: 1597 ITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFI 1656 V + P T++ A P+ + V T P+ K + Q A S+ + Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLPAV-TPPSP--KEPPAPKQVATSSSPKKAPA 1495 Query: 1657 TPVFINSSSIIQVMKGSQPSTIPAAP---------------------LTTNSGLMPPSVA 1695 TP + + ++ V+ S P +PA P L L+PP++ Sbjct: 1496 TPAPMGAPTLPAVIPSS-PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT 1554 Query: 1696 VVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVP 1755 V P P AP P++ +S P + P +P +L PP +SP Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEASSPPAVT---PSTYKGAPSPKELLIPPAVTSPSPK 1611 Query: 1756 SHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSK 1815 P V +P++ + P + S+ SP SP S + Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP---TSPASVTCKMGATVPQA 1668 Query: 1816 GKGKVDKIG-----QILLTKACKK---VTGSLEKGEE-------------QYGADGETEG 1854 KG K G ++L+ A + +T KG + A ++G Sbjct: 1669 SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728 Query: 1855 QGLDTTAPG-LMGTEQLSTEL-----------------DSKTPTPPAPTLLKMTSSPVGP 1896 L T AP L+ ++ S++ +SK TP + Sbjct: 1729 P-LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPES 1787 Query: 1897 GTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGS 1956 + SA PS P +LP + + T + + + P G+ ES + L Sbjct: 1788 ASVSAAPS-PPVSLPLAPSPVPTLPPKQQFLPSSP-------GLVLESPSKPLAP---AD 1836 Query: 1957 HPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRR 2016 ELLP I P +S ++ ++ P+ +A I S + + + +K G Sbjct: 1837 EDELLPLIPPEP--ISGGVPFQSVLVNMPTPK---SAGIPVPTPSAKQPVTKNNKGSGTE 1891 Query: 2017 NSRTEE-PTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRK 2061 + E P + + +++ A+A + ++ A QS+ K Sbjct: 1892 SDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEK 1937 Score = 71.2 bits (173), Expect = 1e-11 Identities = 184/912 (20%), Positives = 300/912 (32%), Gaps = 134/912 (14%) Query: 288 ARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQ-LPSGALQPPPAQGSLGTMTANQGWKK 346 A P P+G P +P P+PP P G L PP +G+ T A K Sbjct: 1079 APTPPAATPPSPKG-GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137 Query: 347 APLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKS 406 L P + P+ P P G+ A P+ G P K Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK----GGLATPSPKG 1193 Query: 407 LQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQG 466 P+ P P + L SP +P+ +PA++P P+ P P+G Sbjct: 1194 APTTPAATP-PSPKGGLATPSPKGAPT-----TPAATPP--------SPKGGLATPSPKG 1239 Query: 467 FQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANP 526 ++ +P PP PP P SL GL P + G NP Sbjct: 1240 APTTPAATPPSPKGGPATPPPK---GAPTPPAATPPSLKGGLATPPHK-------GAPNP 1289 Query: 527 NFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMG 586 + P T GAP A G G PP+ + PP + PS G Sbjct: 1290 AVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG----APTPPAVTPPSPKG 1345 Query: 587 I----------HGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMV 636 G + P + +G P PPS G +PS Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG---PAIPSPKG-- 1400 Query: 637 QQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQR--MTPP--KQMLSQQGPQMM 692 +P +P ++ L P+ + P ++ +P + +TPP + ++ P Sbjct: 1401 ------DPTSPAVI---PLSPK-KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450 Query: 693 APHNQMMGP--QGQVLL--------QQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQ 742 AP P +G L ++ P +Q+ T+ K+ T PA Sbjct: 1451 APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS--SSPKKAPATPAPMGAPTLPAV 1508 Query: 743 IMRGP-----TPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHM 797 I P TP+ + + + T +L ++ P +P + + + P +P + Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPT----ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAI 1564 Query: 798 AQQHGDPATTANNDVSLSQMMPDVSIQ-----QTNMVPPHVQAMQGNSASGNHFSGHGMS 852 PAT ++ + S + + + + ++PP V + A Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624 Query: 853 FNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNL-LQSDISAGHFGVNNKQNNTNA 911 P + AP G S P P + + TSP V + + + G+ K+ T Sbjct: 1625 EKGPATPAPKGTPTS---PPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681 Query: 912 NK---------------PKKKKPPRKKKNSQQDLNTPDTRPAGLEE------ADQPPLPG 950 + P +K P KK ++ PD + A P LP Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLP- 1740 Query: 951 EQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLP 1010 + D+S + ++ P P P E + + + V P P+ P P Sbjct: 1741 ---VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPP 1797 Query: 1011 QQ---QQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQR 1067 P P+ P QQ +++ + P P ++ P P P S Sbjct: 1798 VSLPLAPSPVPTLPPKQQFLPSSPGLVL-----ESPSKPLAPADEDELLPLIPPEPISGG 1852 Query: 1068 MPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVN-----TPLGSNSRKMVYQESPQNPS 1122 +P Q SV V + A +P + P+ N T S+ +E + Sbjct: 1853 VPFQ---SVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQA 1909 Query: 1123 SSPLAEMASLPE 1134 ++ A++A+ E Sbjct: 1910 TTQQAQLAAAAE 1921 Score = 67.4 bits (163), Expect = 1e-10 Identities = 203/946 (21%), Positives = 301/946 (31%), Gaps = 127/946 (13%) Query: 1082 LQGPASVPPSPDKQRMPMPVNTPL-GSNSRKMVYQESPQNPSSSPLAEMASLPEASGS-E 1139 L+G S+ P + PL + S SPQN + +PLA + PE S Sbjct: 677 LEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQN-TCAPLATLVLAPEIPKSVP 735 Query: 1140 APSVPGG---PNNMPSHVVLPQNQL--MMTGPKPGP---SPLSATQGATPQQPPVNSLPS 1191 +PS+P P + + L + + PK P S SAT + + PS Sbjct: 736 SPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS 795 Query: 1192 SHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTP-NNRPPSTEPSEISLSPERLNASIAG 1250 G V+ QT RP T ++ P TP N P E S PE + S G Sbjct: 796 PLG-----VSVSPQTKRPPTKKGSAG----PDTPIGNLSSPVSPVEASFLPEN-SLSFQG 845 Query: 1251 L--FPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSV 1308 P + P PP P +G PT +P +T+ P TP L Sbjct: 846 SKDSPATTHSPTPPSP--------KGA-PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP 896 Query: 1309 VVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSP-GRQNSKAPK--LTLASQTNAALL 1365 K+ + + +P+ S SS + TP+P G S +PK T + T + Sbjct: 897 -----KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK 951 Query: 1366 QNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDS 1425 P P A PP P P +P+ + AA P Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATP--SPKGAPTPPAATP------------PSPK 997 Query: 1426 DCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMR 1485 + S K P+ + P G + P P + +P + Sbjct: 998 GGPATPSPKGAPTPPAVTPPSPKGS---PAATPFPKGASTPPAATPPSPKGSPAATPLPK 1054 Query: 1486 EAPTSLSQLLDN-SGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPS 1544 APT+ + L + G P T TPP G + + ++ P Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK 1114 Query: 1545 NSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSN 1604 L P AP+ P + P ++TP P T Sbjct: 1115 GGLATPPHKG-----------------APTTPAA-TPPSPKGGLATPPPKGAPTT----- 1151 Query: 1605 PITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSS 1664 P T + L T +T P + + + A + TP Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA---TPPSPKGG 1208 Query: 1665 SIIQVMKGSQPSTIPAAPLTTNSGLMPPSV--AVVGPLHIPQNIKFSSAPVPPNALSSSP 1722 KG+ P+T A P + GL PS A P P + K A PP + P Sbjct: 1209 LATPSPKGA-PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267 Query: 1723 APNIQTGRPLVLSSRATPVQ--LPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSAD 1780 A P + ATP P+P + P P K A+ + Sbjct: 1268 AAT----PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323 Query: 1781 QNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLE 1840 T P + T P P G P ++ KG T S + Sbjct: 1324 PGTPPPKGAPT---PPAVTPPSPKGTPTLPATTPSSKGG--------------PTTPSSK 1366 Query: 1841 KGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTAS 1900 +G A +G G T P + + + S P +P ++ P+ P A Sbjct: 1367 EGPTPPAATPSHKG-GPAMTPP----SPKRGPAIPSPKGDPTSPAVI-----PLSPKKAP 1416 Query: 1901 AGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPEL 1960 A P GA S + V + P T + GG A+ S G + + + Sbjct: 1417 ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG---DPTLPAVTPP 1473 Query: 1961 LPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEI 2006 P P+ V+ +S A+ A A++ S PKE+ Sbjct: 1474 SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI---PSSPKEV 1516 Score = 66.6 bits (161), Expect = 2e-10 Identities = 203/899 (22%), Positives = 318/899 (35%), Gaps = 155/899 (17%) Query: 1115 QESPQNPSSS---PLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPS 1171 QE PQ + + P++ S+ A G P++P P P+ P + P P PS Sbjct: 14 QELPQPQAETAVLPMSSALSVTAALGQPGPTLP--PPCSPAPQQCPLSAANQASPFPSPS 71 Query: 1172 PLSAT--QGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNR-ASPRPYYPQTPNNR 1228 +++T + PQ +LP P P P +P A P T Sbjct: 72 TIASTPLEVPFPQSSSGTALPLGTAPEAPTF-LPNLIGPPISPAALALASPMIAPTLKGT 130 Query: 1229 PPSTEP-SEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLN----PTTLKA- 1282 P S+ P + ++L+P + S A FPP + + PP + L+ P+ K Sbjct: 131 PSSSAPLALVALAPHSVQKSSA--FPPNL-LTSPPSVAVAESGSVITLSAPIAPSEPKTN 187 Query: 1283 IGQAPSNLTMNPSNFATP----QTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSR 1338 + + PS + NP +P T V + QS + + +P+ + + + Sbjct: 188 LNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVK 247 Query: 1339 KTTPS--------PGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSF 1390 TT S PG + K P S A L LP V+ S A P P F Sbjct: 248 DTTISSVLISPQNPGSLSLKGP----VSPPAALSLSTQSLP--VVTSSQKTAGPNTPPDF 301 Query: 1391 PNNSG--LNP--QNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPA 1446 P + G L P Q+S SV +G Q S ++ +V Sbjct: 302 PISLGSHLAPLHQSSFGSVQLLG------------------QTGPSALSDPTVKTISVDH 343 Query: 1447 QEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQL------------ 1494 P +S PS +P+ +V+P++ + P+++S + Sbjct: 344 SSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVAT 403 Query: 1495 ---------LDNSGAPNVTIKPP----------GLTDLEVT------------------- 1516 L +PN T P G T L VT Sbjct: 404 SFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCV 463 Query: 1517 -PPVVSG--EDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPE-LSEVSSNVA 1572 PP+ SG +++ S + + KEPS + + L PE L + S+V Sbjct: 464 SPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVL 523 Query: 1573 PSIPPVMS-RPVSSSSISTPLPPNQITVFVTSNP-ITTSANTSAALPTHLQSALMSTVVT 1630 P + V +S P P Q + +P + + QS S + Sbjct: 524 VKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIP 583 Query: 1631 MPNAGSKVMVSEGQSAAQSNARPQFITPVFINSS-SIIQVMKGSQPSTIPAAPLTTNSGL 1689 + + S G+ +P+ +NSS S+I+ + P + A PL S L Sbjct: 584 LSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDS--AGPL-LKSSL 640 Query: 1690 MPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCT 1749 + P+VA PL + + ++ A G + L+ + PV+ T Sbjct: 641 ITPTVAAF-PLESADPAGVAPTTAKGTSTYTTTASPFLEG-TVSLAPKNHPVK--EGTLT 696 Query: 1750 SSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRS 1809 + P+VP+ E P SPQ NT A TL +++P + S S Sbjct: 697 TLPLVPT------ASENCPVAPSPQ-NTCAPLATL-------VLAPEIPKSVPSPS--LP 740 Query: 1810 PVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQ 1869 P + G KVD I T A V S + + TE G TA GT Sbjct: 741 PAGTPPGTKKVDGISH---TSALAPVASSPK--------ECPTEDSGASATASS-KGT-- 786 Query: 1870 LSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLVPSELIS 1928 L+ DS P+P ++ T P SAGP P G L + V + + +P +S Sbjct: 787 LTYLADS--PSPLGVSVSPQTKRP-PTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLS 842 Score = 58.2 bits (139), Expect = 8e-08 Identities = 242/1163 (20%), Positives = 376/1163 (32%), Gaps = 188/1163 (16%) Query: 881 TLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGL 940 TL P Q +SA + +T A+ P + P+ + L T P L Sbjct: 44 TLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFL 103 Query: 941 EEADQPPL-PGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQ 999 PP+ P + P L G PS + P + + A PP Sbjct: 104 PNLIGPPISPAALALASPMIAPTLK-------GTPSSSAPLALVALAPHSVQKSSAFPPN 156 Query: 1000 PPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP-PR 1058 P + + S P + +PK+ V V P P+ Sbjct: 157 LLTSPPSVAVAESGSVITLSAP----------------IAPSEPKTNLNKVPSEVVPNPK 200 Query: 1059 GPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESP 1118 G +P + P+ G AS+P + + + +P ++ SP Sbjct: 201 GTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLA--IASPQVKDTTISSVLISP 258 Query: 1119 QNPSSSPLAEMASLPEASGSEAPSVP--------GGPNNMP-------SHVVLPQNQ--- 1160 QNP S L S P A S+P GPN P SH+ P +Q Sbjct: 259 QNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLA-PLHQSSF 317 Query: 1161 --LMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP---NVAAPTQTSRPKTPNRA 1215 + + G + GPS LS P ++ SS G +P +V P + P Sbjct: 318 GSVQLLG-QTGPSALS-----DPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATV 371 Query: 1216 SPRPYYPQTPNNRPPSTEPSEISLSPE-RLNASIAGLFPPQINIPLPPRPNLNRGFDQQG 1274 + P + + P + S I+ SP LN + + P ++ L PN + Sbjct: 372 AAFPVVAPSVDKGPSTI--SSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVA 429 Query: 1275 LNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSP 1334 P + ++G P +T NP A T + S S+ SN +SP Sbjct: 430 QMP--VSSVGTTPLVVT-NPCTIAAAPTTTFEVATCVSPPMSSGPI------SNIEPTSP 480 Query: 1335 GSSRKTTPSPGRQNSKAPKLTLASQTNAAL-----LQNVELPRNVLVS-PTPLANPPVPG 1388 + +P ++ S TL + L L+N LP +VLV PT VP Sbjct: 481 AALVMAPVAP-KEPSTQVATTLRIPVSPPLPDPEDLKN--LPSSVLVKFPTQKDLQTVPA 537 Query: 1389 SF------PNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELK 1442 S P +GL + + V P++S S S ++ + + Sbjct: 538 SLEGAPFSPAQAGLTTKKDPTVLPLVQA----------APKNSPSFQSTSSSPEIPLSPE 587 Query: 1443 AVPAQEVKMVVPEDQSKKDGQPSDPNKLP-SVEENKNLVSPAMREAPTSLSQLLDNS-GA 1500 A A++ + G+P+ P V + +++ P S LL +S Sbjct: 588 ATLAKK-----SLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLIT 642 Query: 1501 PNVTIKPPGLTD-LEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLN---------LP 1550 P V P D V P G + P L+ S ++ + +P Sbjct: 643 PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVP 702 Query: 1551 HSNELCSSLVHPE-----------LSEVSSNV-APSIPPVMSRP----VSSSSISTPLPP 1594 ++E C P+ E+ +V +PS+PP + P V S ++ L P Sbjct: 703 TASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP 762 Query: 1595 NQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMP-------NAGSKVMVSEGQSAA 1647 V S+P S A T ++ + P + +K ++ SA Sbjct: 763 ------VASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAG 816 Query: 1648 QSNARPQFITPV------FINSSSI-IQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGP- 1699 +PV F+ +S+ Q K S +T P + P +V + P Sbjct: 817 PDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876 Query: 1700 --------------LHIPQNIKFSSAPVPPNA-----LSSSPAPNIQTGRPLVLSSRATP 1740 +++P + + P P A SSSP T P + + +P Sbjct: 877 GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936 Query: 1741 VQLPSPPCTSSPVVPSHPPVQQVK-ELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTN 1799 P+PP + P P K P A+P P T P Sbjct: 937 KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT----PPAAT 992 Query: 1800 SPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDT 1859 P G +P S KG VT KG + Sbjct: 993 PPSPKGGPATP--SPKG------------APTPPAVTPPSPKGSPAATPFPKGASTPPAA 1038 Query: 1860 TAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVT 1919 T P G+ +T L PT PA TL P P A P+ P P+ T Sbjct: 1039 TPPSPKGS-PAATPLPKGAPTTPAATLPSPKGGPATPSLKGA-PTPPAATPPSPKGGPAT 1096 Query: 1920 TLVPSELISAVPTTKSNHGGIAS 1942 + T S GG+A+ Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLAT 1119 Score = 57.0 bits (136), Expect = 2e-07 Identities = 231/1032 (22%), Positives = 360/1032 (34%), Gaps = 175/1032 (16%) Query: 1004 QPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNP 1063 QP P LP P P P S Q + P V P S + Sbjct: 40 QPGPTLPPPCSPAPQQCPLS--AANQASPFPSPSTIASTPLEVPFPQSSS---------- 87 Query: 1064 DSQRMPMQQSGSVPVMV-SLQGPASVPPSPDKQRMPMPV------NTPLGSNSRKMV--- 1113 +P+ + P + +L GP P SP + P+ TP S +V Sbjct: 88 -GTALPLGTAPEAPTFLPNLIGP---PISPAALALASPMIAPTLKGTPSSSAPLALVALA 143 Query: 1114 ---YQES---PQN----PSSSPLAEMASLPEASGSEAPSVP-GGPNNMPSHVVLPQNQLM 1162 Q+S P N P S +AE S+ S APS P N +PS VV Sbjct: 144 PHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVV------- 196 Query: 1163 MTGPKPGPSPLSATQG-----ATPQ---QPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNR 1214 PK PSP TP Q V SLP + +A+P + T + Sbjct: 197 -PNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASP--QVKDTTISS 253 Query: 1215 ASPRPYYPQTPNNRPPSTEPSEISLSPERL-----NASIAGL-----FPPQINIPLPPRP 1264 P P + + + P + P+ +SLS + L + AG FP + L P Sbjct: 254 VLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLH 313 Query: 1265 NLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNS--GATK 1322 + G Q L T A+ P+ T++ + +T ++ V+ N AT Sbjct: 314 QSSFG-SVQLLGQTGPSALSD-PTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATV 371 Query: 1323 RASP--SNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP 1380 A P + S P + T SP + A +L+ T+ L SP Sbjct: 372 AAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKS----------SPNA 421 Query: 1381 LANPPVPGSFPNNS-GLNP--QNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQV 1437 + P+ P +S G P + ++AA + ++ P S + Sbjct: 422 TYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPIS-------- 473 Query: 1438 NIELKAVPAQEVKMVVPEDQSKKDGQ----PSDPNKLPSVEENKNLVSPAMREAPTSLSQ 1493 NIE + A + V P++ S + P P LP E+ KNL S + + PT Sbjct: 474 NIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSP-PLPDPEDLKNLPSSVLVKFPTQ--- 529 Query: 1494 LLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSN 1553 ++ P L +P K +V+P +Q P NS + ++ Sbjct: 530 -------KDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQ-----AAPKNSPSFQSTS 577 Query: 1554 ELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTS 1613 + PE + ++ +P + +P +SS+++PL N + ++ + A Sbjct: 578 SSPEIPLSPEATLAKKSLGEPLP--IGKP--ASSMTSPLGVNSSASVIKTD---SYAGPD 630 Query: 1614 AALPTHLQSALMSTVVTMP-----NAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQ 1668 +A P S + TV P AG ++G S + A P V + + Sbjct: 631 SAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKN--H 688 Query: 1669 VMKGSQPSTIPAAPLTTNSGLMPPS---------VAVVGPLHIPQNIKFSSAP---VPPN 1716 +K +T+P P + + + PS V+ P IP+++ S P PP Sbjct: 689 PVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAP-EIPKSVPSPSLPPAGTPPG 747 Query: 1717 A--------------LSSSP--APNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPV 1760 ++SSP P +G SS+ T L P SP+ S P Sbjct: 748 TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP---SPLGVSVSPQ 804 Query: 1761 QQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPV---SSSKGK 1817 + A P L S S S L NS G++ SP S + Sbjct: 805 TKRPPTKKGSAGPDTPI----GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860 Query: 1818 GKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSK 1877 K + + K VT ++ + +G T AP +++ K Sbjct: 861 PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920 Query: 1878 TPTPPAPTLLKMTSSPVGPGT--ASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKS 1935 PAP + + SP G T A+ PS GG S + P+ + P+ K Sbjct: 921 ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK-----WAPTPPAATPPSPK- 974 Query: 1936 NHGGIASESLAG 1947 GG A+ S G Sbjct: 975 --GGPATPSPKG 984 Score = 48.9 bits (115), Expect = 5e-05 Identities = 172/826 (20%), Positives = 286/826 (34%), Gaps = 126/826 (15%) Query: 1222 PQTPNNRP-PSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTL 1280 P T P P E + + +S + G P + P P P Q L+ Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQ------QCPLSAANQ 63 Query: 1281 KAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKT 1340 + +PS + P PQ+ ++ + + ++ + P S + +S Sbjct: 64 ASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMI 123 Query: 1341 TPS-PGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQ 1399 P+ G +S AP L L + ++ ++ P N+L SP +A ++ + P Sbjct: 124 APTLKGTPSSSAP-LALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPS 182 Query: 1400 NSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSK 1459 ++ V V N + P + VP V + S Sbjct: 183 EPKTNLNKVPSEVVPNPKGTPSPP---------------CIVSTVPYHCVTPMA----SI 223 Query: 1460 KDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPV 1519 + G S P P+ + SP +++ S S L+ ++++K P V+PP Sbjct: 224 QSGVASLPQTTPTT--TLAIASPQVKDTTIS-SVLISPQNPGSLSLKGP------VSPPA 274 Query: 1520 VSGEDLKKASVIPTLQDLSSSKEPSN---SLNLPHSNELCSSLVHPELSEVSSNVAPSIP 1576 + V+ + Q + P + SL + SS +L + A S P Sbjct: 275 ALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDP 334 Query: 1577 PVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQS-----ALMSTVVTM 1631 V + V SS P + + + T AA P S + +S++ Sbjct: 335 TVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCS 394 Query: 1632 PNAGSKVMVSEGQSAAQS-------NARPQFITPVFINSSSI-IQVMKGSQPSTIPAAPL 1683 P+ V S S S NA + + SS+ + + P TI AAP Sbjct: 395 PSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPT 454 Query: 1684 TTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQL 1743 TT + ++ PP +SS P NI+ P L + Sbjct: 455 TT--------------------FEVATCVSPP--MSSGPISNIEPTSPAALVMAPVAPKE 492 Query: 1744 PSPPCTSSPVVPSHPPVQQVKELN--PDEASPQVNTSADQNTLPSS-------------- 1787 PS ++ +P PP+ ++L P + T D T+P+S Sbjct: 493 PSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLT 552 Query: 1788 -QSTTMVSPLLTNSPGSSGNRRS-------PVSSSKGKGKVDKIGQILLTKACKKVTGSL 1839 + V PL+ +P +S + +S P+S K + + K +T L Sbjct: 553 TKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPL 612 Query: 1840 EKGEEQYGADGETEG-QGLDTTAP----GLMGTEQLSTELDSKTPTPPAPTLLKMTS--- 1891 G + +T+ G D+ P L+ + L+S P APT K TS Sbjct: 613 --GVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYT 670 Query: 1892 ---SPVGPGTASAGPS---LPGGALPTSVRSIVTTLVP--SELISAVPTTKSNHGGIASE 1943 SP GT S P + G L T LVP SE P+ ++ +A+ Sbjct: 671 TTASPFLEGTVSLAPKNHPVKEGTLTT------LPLVPTASENCPVAPSPQNTCAPLATL 724 Query: 1944 SLAGGLVEEKVGSHPELLPS-IAPSQNLVSKETSTTALQASVARPE 1988 LA + K P L P+ P V + T+AL + P+ Sbjct: 725 VLAPEI--PKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPK 768 Score = 35.8 bits (81), Expect = 0.45 Identities = 65/335 (19%), Positives = 99/335 (29%), Gaps = 39/335 (11%) Query: 162 EAGFPMASGPGIIR-MNNPATVMIPPGGNVSSSMMAPGP------NPELQPRTPRPASQS 214 EA P A P + +P ++IPP S AP P +PE P TP P Sbjct: 1578 EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637 Query: 215 DAMDPLLSGLHIQQQSHPS-----GSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQ 269 + S L S S G+ P P + P ++ + Sbjct: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA----KKGPTALKEVLVAPAPEST 1693 Query: 270 QQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPP 329 ++ Q ++ PP G + + P+ P A Sbjct: 1694 PIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD 1753 Query: 330 PAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTN 389 + G + + PL +++ +P A+V PP P A + Sbjct: 1754 ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPL-------APSP 1806 Query: 390 FPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQT 449 P + QF + PS+ P + L P P G P S VN Sbjct: 1807 VPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELL---PLIPPEPISGGVPFQSVLVNM- 1862 Query: 450 QQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGN 484 P P+ PV +P V + N Sbjct: 1863 ------------PTPKSAGIPVPTPSAKQPVTKNN 1885 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 103 bits (257), Expect = 2e-21 Identities = 258/1150 (22%), Positives = 362/1150 (31%), Gaps = 190/1150 (16%) Query: 140 AQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPP--GGNVSSSMMAP 197 AQ RS M+ P +G + A P S P M+ + P G N S P Sbjct: 353 AQQRSHHAPMS-PGSSGGGGQPLARTPQPSSP----MDQMGKMRPQPYGGTNPYSQQQGP 407 Query: 198 GPNPEL------QP---RTPR--PASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPV 246 P+ QP +TP+ P + + GL QQ P G P + Q Sbjct: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQ 467 Query: 247 S--VNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRP 304 + N+Q P QQQQ QQ Q Q QQQ Q++PPQ Q P +P Sbjct: 468 TPYYNQQS-----PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP 522 Query: 305 QFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLA 364 Q P P + S Q P +Q + + P QQQ +P+ + Sbjct: 523 SQPPHQQSPAP--YPSQQSTTQQHPQSQ---------PPYSQPQAQSPYQQQQPQQPAPS 571 Query: 365 TVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQ-------FTAPQMKSLQGGPSRVPTP 417 T+ + P P SQQ + + FP Q +AP M S +GG + Sbjct: 572 TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631 Query: 418 LQQ-----PHLT---NKSPASSPSSFQQG---SPASSPTVNQTQQQMGPRPPQNNPLPQG 466 LQ P L+ + P + + G S SS Q+ P P +P G Sbjct: 632 LQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPG 691 Query: 467 FQ----QPVSSPGRNPMVQQGNVPPNFMVMQQQPP----NQGPQSLHPGLGGMPKRLPPG 518 + PV SP + G + P + Q PP Q +HP + G Sbjct: 692 IRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRG 751 Query: 519 FSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPN 578 + Q NP Q+P ++ PG++ +P+ Q +GGQ H Sbjct: 752 YM--QRNP-----QMPQYSSPQPGSALSPR-------QPSGGQ-----------IHTGMG 786 Query: 579 MMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQ 638 Q + MG +G Q G P+ N P PS M + + GQM Q Sbjct: 787 SYQQNSMGSYGPQGGQYGPQGGYPR--QPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ 844 Query: 639 QGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQM 698 G + P + R G P N+ P Q G M P M Sbjct: 845 PG-IPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------------QVGSGMCPPPGGM 890 Query: 699 MGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVM-PGPAQIMRGPTPNMQGNMVQ 757 Q+ + + N +Q + NQ +M GP G N M+ Sbjct: 891 -----NRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPY---GQGINSMAGMIN 942 Query: 758 FTG---QMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSL 814 G M G M + SP ++MG+ L P + A G P T + + S Sbjct: 943 PQGPPYSMGGTMANNSAGMAASP-EMMGLGDVKLTPATKMNNKAD--GTPKTESKSKKSS 999 Query: 815 SQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGF 874 S + I + + G +M + F Sbjct: 1000 SSTTTNEKITKLYEL-----------------------------GGEPERKMWVDRYLAF 1030 Query: 875 PVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKN--------- 925 K + +T+ V D+ + V T NK KK + N Sbjct: 1031 TEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAAS 1090 Query: 926 --SQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPL 983 +Q + +E + PP + S PK+ S P G S Q P Sbjct: 1091 SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPS--PAGSGSMQGPQTPQ 1148 Query: 984 QQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQS-----QQQQQQQQQMMMMLM 1038 PP P P Q PP P +S Q Sbjct: 1149 STSSSMAEGGDLKPPTP------ASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKR 1202 Query: 1039 MQQDPKSVRLPVSQNVHPPRGPLNPDSQRMP----MQQSGSVPVMVSLQGPASVPPSP-D 1093 P P S N G ++ + + P + GS P M S QGP P Sbjct: 1203 NSMTPNPGYQP-SMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYS 1261 Query: 1094 KQRMPMPVNTPLGSNSRKMV---YQESPQNPSSSPLAEM---ASLPEASGSEAPSVPGGP 1147 + P N +G Y P P M A P S S P Sbjct: 1262 RAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSP 1321 Query: 1148 NNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTS 1207 + P PQ Q +TQG TP P S ++ V++P Sbjct: 1322 SRYP-----PQQQQQQQQRHDSYGNQFSTQG-TPSGSPFPSQQTTMYQQQQQVSSPAPLP 1375 Query: 1208 RPKTPNRASP 1217 RP NR SP Sbjct: 1376 RP-MENRTSP 1384 Score = 99.8 bits (247), Expect = 3e-20 Identities = 230/996 (23%), Positives = 346/996 (34%), Gaps = 186/996 (18%) Query: 937 PAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYP--SQPVEQRPLQQMPPQLMQHV 994 P+G + Q P +Q + + P +S +PP +QP Q+ Q PPQL Sbjct: 459 PSGYGQQGQTPYYNQQS---PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQ 515 Query: 995 AP----PPQPPQQQ-----PQPQLPQQQQP---PPPSQPQSQQ--QQQQQQQMMMMLMMQ 1040 P P QPP QQ P Q QQ P PP SQPQ+Q QQQQ QQ + Q Sbjct: 516 PPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQ 575 Query: 1041 -------QDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQG--------- 1084 Q +S + SQ PP L+ DS Q+ S P M S +G Sbjct: 576 QAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG---SQASSAPSMTSSKGGQEDMNLSL 632 Query: 1085 ---PASVPP-SPDKQRMPMPVN---TPLGSNSRKMVYQESPQNPSSSPLAEMAS--LPEA 1135 P+S+P S +PM +P S S Q NP+ SP + S LP Sbjct: 633 QSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGI 692 Query: 1136 SGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVN--SLPSSH 1193 G +PS G P ++ P + + G + P P S Q + P +N S+ Sbjct: 693 RG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG-QSDSIMHPSMNQSSIAQDR 750 Query: 1194 GHHFPNVAAPTQTSRPKTPNRASPR-PYYPQTPNNRPPSTEPSEISLSPERLNASIAGLF 1252 G+ N P Q S P+ + SPR P Q + S S P+ G + Sbjct: 751 GYMQRNPQMP-QYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGY 809 Query: 1253 PPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNS 1312 P Q N P N G+NP + A GQ + P P Sbjct: 810 PRQPNYNALPNANYPSAGMAGGINP--MGAGGQMHGQPGIPPYGTLPP------------ 855 Query: 1313 GKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPR 1372 G+ S++ R N P P PG N K + +A A +QN Sbjct: 856 GRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGY 915 Query: 1373 NVLVSPTPLANPPVPGSFPNNSG--LNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNS 1430 + + P G N+ +NPQ S +GG + +N + Sbjct: 916 PNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYS---MGGTMANNSAGM----------- 961 Query: 1431 QSRKEQVNI-ELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPT 1489 + E + + ++K PA ++ +K DG P E+K+ S + Sbjct: 962 AASPEMMGLGDVKLTPATKM-------NNKADGTPK--------TESKSKKSSSSTTTNE 1006 Query: 1490 SLSQLLDNSGAPNVTI-----------KPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLS 1538 +++L + G P + K G+T+L P V + L + +++++ Sbjct: 1007 KITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNL----PAVGRKPLDLYRLYVSVKEIG 1062 Query: 1539 SS---------KEPSNSLNLPHSNELCSSLVHPELS---------EVSSNVAPSIPPVMS 1580 +E + +LN+ S+ SSL + E + P I Sbjct: 1063 GLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAAD 1122 Query: 1581 RPVSSSSISTPLPPNQITVFVTSNPITTSAN----------TSAALPTHLQSALMSTVVT 1630 S I P P ++ P +TS++ T A+ P H Q + + Sbjct: 1123 SKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTP-HSQIPPLPGMSR 1181 Query: 1631 MPNAGSKVMVSEGQSAAQSNARPQFITPVF---INSSSIIQVMK--------GSQPSTIP 1679 + G + ++G + P + +N+S ++ M GS Sbjct: 1182 SNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPG 1241 Query: 1680 AAPLTT-----NSGLMPPSVAVVGP----------LHIPQNIKFSSAPVPPNALSSSPAP 1724 + P + N G+ P GP H P + P P Sbjct: 1242 SDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGI---GPEG 1298 Query: 1725 NIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPP-VQQVKELNPDEASPQVNTSADQNT 1783 N+ TG P P +PS P + +PP QQ ++ D Q +T + Sbjct: 1299 NMSTGAP-------QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSG 1351 Query: 1784 LP-SSQSTTMVSPLLTNS-----PGSSGNRRSPVSS 1813 P SQ TTM S P NR SP S Sbjct: 1352 SPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKS 1387 Score = 63.9 bits (154), Expect = 2e-09 Identities = 123/555 (22%), Positives = 189/555 (34%), Gaps = 83/555 (14%) Query: 972 GYPSQPVEQRPLQQMPPQLMQHVAPPP----QPPQQQPQPQLPQQQQPPPPSQPQSQQQQ 1027 G QP+ + P P M + P P P QQ P QQ P QP Q Sbjct: 368 GGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427 Query: 1028 QQQQQMMMMLMMQQDPKSVR--LPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGP 1085 Q+ + MQ +S L +Q + PP G P Q G P Sbjct: 428 QRYP-----MTMQGRAQSAMGGLSYTQQI-PPYGQQGPSGYG----QQGQTPYYNQQS-- 475 Query: 1086 ASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPG 1145 P P +Q+ P P + + YQ+ PQ S P + + P + P Sbjct: 476 ----PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ--SQPPQLQSSQPPYSQQPSQPPHQQ 529 Query: 1146 GPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQ 1205 P PS Q P P S Q PQQP ++L Q Sbjct: 530 SPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQ-------------Q 576 Query: 1206 TSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPN 1265 + P+ ++ S + Y Q PP E S+ S + +A P + + + Sbjct: 577 AAYPQPQSQQSQQTAYSQ--QRFPPPQELSQDSFGSQASSA-------PSMTSSKGGQED 627 Query: 1266 LNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRAS 1325 +N + P++L + + +L M +P + + G+QSN A Sbjct: 628 MNLSLQSR---PSSLPDLSGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNP-----AQ 678 Query: 1326 PSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPP 1385 S +SP PSP S A +Q+ + L +P N + PP Sbjct: 679 SPFSPHTSPHLPGIRGPSPSPVGSPAS----VAQSRSGPLSPAAVPGNQM--------PP 726 Query: 1386 VPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNS------QSRKEQVNI 1439 P S ++S ++P + S+A G ++ N + +PQ S Q Q Q++ Sbjct: 727 RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ---MPQYSSPQPGSALSPRQPSGGQIHT 783 Query: 1440 ELKAVPAQEVKMVVPE--DQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSL---SQL 1494 + + + P+ + G P PN + N N S M + Q+ Sbjct: 784 GMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNY--NALPNANYPSAGMAGGINPMGAGGQM 841 Query: 1495 LDNSGAPNVTIKPPG 1509 G P PPG Sbjct: 842 HGQPGIPPYGTLPPG 856 Score = 50.1 bits (118), Expect = 2e-05 Identities = 87/370 (23%), Positives = 124/370 (33%), Gaps = 83/370 (22%) Query: 372 PPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKS------LQGGPSRVPTPLQQPH--- 422 PP + + SQ P + G PQ +GG + PTP PH Sbjct: 1114 PPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQI 1173 Query: 423 -----LTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRN 477 ++ + +F GS ++ Q + M P P G+Q P N Sbjct: 1174 PPLPGMSRSNSVGIQDAFNDGSDSTF----QKRNSMTPNP--------GYQ-----PSMN 1216 Query: 478 PMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLP---PGFSAGQANPNFMQGQVP 534 G + PN+ P G ++ P P S+GQ PN G P Sbjct: 1217 TSDMMGRM--------SYEPNKDPY-------GSMRKAPGSDPFMSSGQ-GPNGGMGD-P 1259 Query: 535 STTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQ 594 + A PG G + Q+ + G P ++++ G +G GNM Sbjct: 1260 YSRAAGPG-LGNVAMGPRQHYPYGG------PYDRVRTEPG---------IGPEGNM--- 1300 Query: 595 QAGTSGVPQVNLSNMQGQPQQGP------PSQLMGMHQQIVPSQGQMVQQQGTLNPQNPM 648 ++G PQ NL M P G P Q QQ S G QGT P Sbjct: 1301 ---STGAPQPNL--MPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGT--PSGSP 1353 Query: 649 ILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQ 708 S+ M Q Q V+ P+ P R +P K G +M + Sbjct: 1354 FPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPV 1413 Query: 709 QNPMIEQIMT 718 Q PMI + +T Sbjct: 1414 QPPMIRRDIT 1423 Score = 34.7 bits (78), Expect = 0.99 Identities = 41/173 (23%), Positives = 56/173 (32%), Gaps = 20/173 (11%) Query: 154 GAGNSVRMEAGFPMASGPGI------IRMNNPA-----TVMIPPGGNVSSSMMAPGPNPE 202 G G + M + A+GPG+ R + P V PG +M P P Sbjct: 1249 GQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPN 1308 Query: 203 LQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQ 262 L P P S + P QQQ H S S + + FP Q Sbjct: 1309 LMPSNPDSGMYSPSRYPPQQQQQ-QQQRHDSYG--------NQFSTQGTPSGSPFPSQQT 1359 Query: 263 QQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVP 315 QQQQQ + + + ++ P H + Q P A P P Sbjct: 1360 TMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAP 1412 Score = 34.3 bits (77), Expect = 1.3 Identities = 54/243 (22%), Positives = 74/243 (30%), Gaps = 46/243 (18%) Query: 901 GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPL------PGEQGI 954 G+ + N+ + + +K+ Q +NT D E ++ P PG Sbjct: 1186 GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPF 1245 Query: 955 NLDNSGPK--LPEFSNRPPGYPSQPVEQRPLQQMP---PQLMQHVAPPPQP--------P 1001 GP + + +R G V P Q P P P P P Sbjct: 1246 MSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAP 1305 Query: 1002 QQQPQPQLPQQQQPPPPSQPQSQQQQQQQ----------------------QQMMMMLMM 1039 Q P P P P QQQQQQQ QQ M Sbjct: 1306 QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQ 1365 Query: 1040 QQ--DPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRM 1097 QQ P + P+ P + P +M Q PV S PA V P ++ + Sbjct: 1366 QQVSSPAPLPRPMENRTSPSKSPFLHSGMKM---QKAGPPVPASHIAPAPVQPPMIRRDI 1422 Query: 1098 PMP 1100 P Sbjct: 1423 TFP 1425 Score = 33.9 bits (76), Expect = 1.7 Identities = 76/410 (18%), Positives = 134/410 (32%), Gaps = 52/410 (12%) Query: 1532 PTLQDLSSSKEPSNSLNLPHSNELCSSLVHPEL------SEVSSNVAPSIPPVMSRPVSS 1585 P+ Q S+ P + P ++ S H + + ++ P P S+P + Sbjct: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQ 557 Query: 1586 SSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQS 1645 S P P ++ + AA P T + +S+ Sbjct: 558 SPYQQQQP---------QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608 Query: 1646 AAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAA-------PLTTNSGLMPPSVAVVG 1698 +Q+++ P + + + S+PS++P P+ T G + P V+ G Sbjct: 609 GSQASSAPSMTSSK--GGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE-GALSPGVSTSG 665 Query: 1699 PLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHP 1758 + Q + + A P + +S P I+ P + S A+ Q S P + + V + Sbjct: 666 -ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQM 724 Query: 1759 PVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKG 1818 P + + P +N S+ Q + + PGS+ + R P G Sbjct: 725 PPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTG 784 Query: 1819 KVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAP----------GLMGTE 1868 + + GS QYG G Q P G + Sbjct: 785 ---------MGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPM 835 Query: 1869 QLSTELDSKTPTPPAPTL-------LKMTSSPVGPGTASAGPSLPGGALP 1911 ++ + PP TL M + P GP A+ P + G P Sbjct: 836 GAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCP 885 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 102 bits (255), Expect = 3e-21 Identities = 262/1111 (23%), Positives = 370/1111 (33%), Gaps = 250/1111 (22%) Query: 200 NPELQPRTPRPA---SQSDAMDPLL----------SGLHIQQQS---HPSGSLAPPHHPM 243 +P + P TP P SQ MDP++ S H Q Q +P GS PP Sbjct: 440 HPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQR 499 Query: 244 QPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIR 303 P+ + + P +Q QQQ Q QQ QQ QQ P QQ QP + Sbjct: 500 YPIGIQGR-TPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ-----PYYSQQPQPPHL- 552 Query: 304 PQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSL 363 PP AQ LP QQ+ Q + + Sbjct: 553 ------------------------PPQAQY---------------LPSQSQQRYQPQQDM 573 Query: 364 ATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHL 423 + + PP G + + N Q P + L G +PT + Sbjct: 574 SQEGYGTRSQPPLAPG--KPNHEDLNLIQQERPSS-----LPDLSGSIDDLPTGTEATLS 626 Query: 424 TNKSPASSPSSF-QQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPV-SSPGRNPMVQ 481 + S + S SS Q +PA SP + P +P P G PV S+ R+ + Sbjct: 627 SAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVG--SPVGSNQSRSGPIS 684 Query: 482 QGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAG-QANPNFMQ-GQVPSTTAT 539 ++P + M Q P +Q S HP L P GF AG Q NP Q G + + Sbjct: 685 PASIPGSQMP-PQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSM 743 Query: 540 TPGNSGAPQLQAN-QNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGT 598 +P S Q+ A + Q + G ++GP Q S G GN + A Sbjct: 744 SPHPSPGGQMHAGISSFQQSNSSG----------TYGP----QMSQYGPQGNYSRPPA-Y 788 Query: 599 SGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQ 658 SGVP + S P MG+ S + QG P + L R MP Sbjct: 789 SGVPSASYSG---------PGPGMGI------SANNQMHGQGPSQPCGAVPLGR---MPS 830 Query: 659 GQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMT 718 M P N+ MTP +SQQG M P + + Q + + Q Sbjct: 831 AGMQNRPFPGNMSS----MTPSSPGMSQQGGPGMGPPMPTVNRKAQ---EAAAAVMQAAA 883 Query: 719 NQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPS 778 N Q + F NQS +M + + P N S M Q P + +P+ Sbjct: 884 NSAQSRQGSFPGMNQSGLMASSSPYSQ-PMNNS-----------SSLMNTQAPPYSMAPA 931 Query: 779 QVMGIQGQV----LRPPG----PSPHMA--QQHGDPATTANNDVSLSQMMPDVSIQQTNM 828 V V + PG P P A ++ G P + + S S +S T Sbjct: 932 MVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQ--GISQPPTPG 989 Query: 829 VPPHVQAMQGNSASGNHFSG-HGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLL 887 P M +SAS + F G S ++P G P + P P + T T + Sbjct: 990 NLPVPSPMSPSSASISSFHGDESDSISSP--GWP--------KTPSSPKSSSSTTTGEKI 1039 Query: 888 VNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPP 947 + + N+P++K + ++ +P + L + P Sbjct: 1040 TKVYEL-----------------GNEPERKLWVDRYLTFMEERGSP---VSSLPAVGKKP 1079 Query: 948 LPGEQ---------GINLDNSGPKLPEFS-NRPPGYPSQPVEQRPLQQMPP------QLM 991 L + G+ N K E + N G S Q + ++ Sbjct: 1080 LDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIE 1139 Query: 992 QHVAPPPQ---PPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRL 1048 + PPP+ + QP+L QPP P+ S Q Q Q M + Sbjct: 1140 RGEEPPPEVFSTGDTKKQPKL----QPPSPANSGSLQGPQTPQSTGSNSMAE-------- 1187 Query: 1049 PVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPAS-VPPSPDKQRMPMPVNTPLGS 1107 V ++ PP P Q PMQ G +S+ P S V S +R M N P Sbjct: 1188 -VPGDLKPPTPASTPHGQMTPMQ--GGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQ 1244 Query: 1108 N-SRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGP 1166 S V P P+ P M +P GS P + G MP N M Sbjct: 1245 GMSMPDVMGRMPYEPNKDPFGGMRKVP---GSSEPFMTQG--QMP-------NSSMQDMY 1292 Query: 1167 KPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPN 1226 PS + G +Q FP A+ + P Y Q P Sbjct: 1293 NQSPSGAMSNLGMGQRQ------------QFPYGASYDRRHEP----------YGQQYPG 1330 Query: 1227 NRPPSTEPSEISLSPERLNASIAGLFPPQIN 1257 PPS +P P GL+P Q N Sbjct: 1331 QGPPSGQPPYGGHQP--------GLYPQQPN 1353 Score = 89.0 bits (219), Expect = 4e-17 Identities = 310/1377 (22%), Positives = 451/1377 (32%), Gaps = 268/1377 (19%) Query: 260 LQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWN 319 LQQQ Q QQQQQQQQQQQQQQQQQQ + G PQ + P G Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQHPI--SNNNSLGGAGGGAPQPGPDMEQPQHGGAK 105 Query: 320 QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR---PSLATVQTPSHPPPPY 376 +G PP G ++ + P M + R P L + T PP Sbjct: 106 DSAAGGQADPP-----GPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGT-QQPPVAV 159 Query: 377 PFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPA----SSP 432 P G + P+ +N AP GGP P H +SP S Sbjct: 160 PGGGGGPAAV----PEFNNYYGSAAP----ASGGPGGRAGPCFDQHGGQQSPGMGMMHSA 211 Query: 433 SSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVM 492 S+ G+P S + + + G Q N P G+ +P + G Sbjct: 212 SAAAAGAPGSMDPLQNSHE--GYPNSQCNHYP-GYSRPGAGGGGG--------------- 253 Query: 493 QQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQAN 552 G S G GG G AG A + + A G G Sbjct: 254 --GGGGGGGGSGGGGGGG-------GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY---- 300 Query: 553 QNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQ 612 GG AG G MM P G + +G GQ Sbjct: 301 ------GGSSAGYGVLSSPRQQGGGMMMGPG----GGGAASLSKAAAGSAAGGFQRFAGQ 350 Query: 613 PQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQ--NPMILSRAQLMPQGQMMVNPPS--- 667 Q PS Q++ S M++ G P+ +P PQ Q + Sbjct: 351 NQH--PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGG 408 Query: 668 ----------QNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVL--LQQNPMIEQ 715 +++G +P Q+ M+P G G + Q +PM Sbjct: 409 QQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP-----GTPGPTMGRSQGSPMDPM 463 Query: 716 IMTN-QMQGNKQQFNTQ-NQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPV 773 +M Q+ G ++Q QS+ PG + GP G + G M+G PQQ Sbjct: 464 VMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQ--- 520 Query: 774 NNSPSQV--MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPP 831 P Q G+ G + G P+ +QQ P +Q +P S Q+ Sbjct: 521 -QMPPQYGQQGVSGYCQQ--GQQPYYSQQPQPPHLPPQ-----AQYLPSQSQQR------ 566 Query: 832 HVQAMQGNSASGNHFSGHGMSFNAPFS-GAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNL 890 Q Q S G+G P + G PN ++ Q D++ + L Sbjct: 567 -YQPQQDMSQ-----EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTG 620 Query: 891 LQSDISAGHFGVNNKQNNTNANKPKKKK-PPRKKKNSQQDLNTPDTRPAGLEEADQPPLP 949 ++ +S+ + + + + P + P + P P G Sbjct: 621 TEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVG---------- 670 Query: 950 GEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQL 1009 G N SGP P P QMPPQ PP + P L Sbjct: 671 SPVGSNQSRSGPISP--------------ASIPGSQMPPQ------PPGSQSESSSHPAL 710 Query: 1010 PQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP-PRGPLNPD-SQR 1067 Q P P + Q+ QM Q P S + HP P G ++ S Sbjct: 711 ---SQSPMPQERGFMAGTQRNPQMAQYGPQQTGP-------SMSPHPSPGGQMHAGISSF 760 Query: 1068 MPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLA 1127 SG+ +S GP G+ SR Y P S P Sbjct: 761 QQSNSSGTYGPQMSQYGPQ-------------------GNYSRPPAYSGVPSASYSGPGP 801 Query: 1128 EMA-SLPEASGSEAPSVPGGP---NNMPS----HVVLPQNQLMMTGPKPGPSPLSATQGA 1179 M S + PS P G MPS + P N MT PG S G Sbjct: 802 GMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQ-QGGPGM 860 Query: 1180 TPQQPPVNSLPSSHGHHFPNVAAPTQTSRP-------KTPNRASPRPY-YPQTPNNRPPS 1231 P P VN AA + SR ++ AS PY P ++ + Sbjct: 861 GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMN 920 Query: 1232 TEPSEISLSPERLNASIAG------LFPPQINIPLP----------PRPNLNRGFDQQGL 1275 T+ S++P +N+S A + P + +PLP P+P + + Sbjct: 921 TQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQP------ESKSK 974 Query: 1276 NPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNS--GKQSNSGATKRASPSNSRR-S 1332 + + + I Q P+ P N P S ++S G +S+S +SP + S Sbjct: 975 DSYSSQGISQPPT-----PGNLPVPSPMSPSSASISSFHGDESDS----ISSPGWPKTPS 1025 Query: 1333 SPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPN 1392 SP SS TT G + +K +L + + + + +P+++ P G P Sbjct: 1026 SPKSSSSTT--TGEKITKVYELGNEPERKLWVDRYLTFMEE---RGSPVSSLPAVGKKP- 1079 Query: 1393 NSGLNPQNSTVSVAAVGGVVEDNKE--------SLNVPQDSDCQNSQSRKE-------QV 1437 L+ V V +GG+ + NK +LNV S +S ++ + Sbjct: 1080 ---LDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFEC 1136 Query: 1438 NIELKAVPAQEVKMVVPEDQSKKDGQPSDPN--KLPSVEENKNLVSPAMREAPTSLSQLL 1495 IE P EV + K PS N L + ++ S +M E P L Sbjct: 1137 KIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLK--- 1193 Query: 1496 DNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHS 1552 P P G ++TP + G SV D+S S P + P++ Sbjct: 1194 ----PPTPASTPHG----QMTP--MQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNA 1240 Score = 72.8 bits (177), Expect = 3e-12 Identities = 224/1066 (21%), Positives = 338/1066 (31%), Gaps = 189/1066 (17%) Query: 106 ERLRILAQSNNQQLRDLG--ILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEA 163 E L ++ Q L DL I + E ++ A++ + S + + A + A Sbjct: 594 EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHA 653 Query: 164 GFPMASGPGIIRMNNPATVMIPPGGNVS-SSMMAPG--PNPELQPRTPRPASQSDAMDPL 220 ++S PG +P+ V P G N S S ++P P ++ P+ P S+S + L Sbjct: 654 SPHLSSIPG---GPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPAL 710 Query: 221 LSGLHIQQQSHPSGSLAPPHHPMQ-PVSVNRQMNPANFPQLQQQQQQQQQQQQQQQ---- 275 Q++ +G+ P P M+P P Q QQ Sbjct: 711 SQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYG 770 Query: 276 QQQQQQQQQQLQARPP-----------------------QQHQQ--QQPQGIRPQFTAPT 310 Q Q Q +RPP Q H Q QP G P P+ Sbjct: 771 PQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPS 830 Query: 311 --------------QVPVPPGWNQLPSGALQPP---------PAQGSLGTMTANQGW-KK 346 P PG +Q + PP A ++ AN ++ Sbjct: 831 AGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQ 890 Query: 347 APLPG-----------PMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSN 395 PG P Q + SL Q P + P S AS M + Sbjct: 891 GSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS---VGLADMMS 947 Query: 396 PGQFTAPQMKSLQGGPSRVPTP------------LQQPHLTNKSPASSPSSFQQGSPASS 443 PG+ P G P P + QP P SP S S SS Sbjct: 948 PGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSAS-ISS 1006 Query: 444 PTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQ----QPPNQ 499 +++ P P+ P+ + + + GN P + + + Sbjct: 1007 FHGDESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERG 1066 Query: 500 GPQSLHPGLGGMPKRLPPGF-------SAGQANPNFMQGQVPSTTATTPGNSGAPQLQAN 552 P S P +G P L + Q N N ++ + +S A L+ Sbjct: 1067 SPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLK-K 1125 Query: 553 QNVQHAGG------QGAGPPQNQMQV--SHGPPNMMQPSLMG---IHGNMNNQQAGTSGV 601 Q +Q+ +G PP + P + PS + G Q G++ + Sbjct: 1126 QYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSM 1185 Query: 602 PQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMI-LSRAQLMPQGQ 660 +V PP+ H Q+ P QG + T++ +P +S + + Sbjct: 1186 AEV-------PGDLKPPTPASTPHGQMTPMQGG---RSSTISVHDPFSDVSDSSFPKRNS 1235 Query: 661 MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ 720 M N P Q Q M+ P M G P+ G +V P + Q Sbjct: 1236 MTPNAPYQ------QGMSMPDVM----GRMPYEPNKDPFGGMRKVPGSSEPFMTQ----- 1280 Query: 721 MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQ---GNMVQFTGQMSGQMLPQQGPVNNSP 777 G + Q+ N P A G Q G + GQ P QGP + P Sbjct: 1281 --GQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQP 1338 Query: 778 SQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQ 837 G + P HM +G PA D+ Q S QQ M + Sbjct: 1339 PYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQY----SSQQQEMYNQY----- 1389 Query: 838 GNSASGNHFSGHGMSFNAPFSGA-PNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDIS 896 G +SG P G P Q PG + ++ LQS S Sbjct: 1390 -----GGSYSGPD---RRPIQGQYPYPYSRERMQGPGQIQTHGIP--PQMMGGPLQSSSS 1439 Query: 897 AGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINL 956 G Q N A + P + ++ P G +A PP PG +N Sbjct: 1440 EG------PQQNMWAARNDMPYPYQNRQG-----------PGGPTQA--PPYPG---MNR 1477 Query: 957 DNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQ--QQ 1014 + + N +PS +++P MQ + PPQP Q P P LP + Sbjct: 1478 TDDMMVPDQRINHESQWPSHVSQRQPYMSSSAS-MQPITRPPQPSYQTP-PSLPNHISRA 1535 Query: 1015 PPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGP 1060 P P S +S + + + + M+ +P SQ PP P Sbjct: 1536 PSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQP 1581 Score = 70.1 bits (170), Expect = 2e-11 Identities = 251/1147 (21%), Positives = 367/1147 (31%), Gaps = 255/1147 (22%) Query: 429 ASSPSSFQQGSPASS--PTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVP 486 A+S S GS A Q Q G P N L S G P + P Sbjct: 329 AASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAP 388 Query: 487 PNFMVMQQQPPNQGPQSLHPGLG----------GMPKRLPPGFSAGQANPNFMQGQVPST 536 P PP PQS G GM G A+P + Q S Sbjct: 389 P--------PPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSH 440 Query: 537 TATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQA 596 A +PG G G+ G P + M M +P L G+ N ++Q Sbjct: 441 PAMSPGTPGPTM-----------GRSQGSPMDPMV-------MKRPQLYGMGSNPHSQPQ 482 Query: 597 GTSGVPQVNLSNMQGQPQQGP-------PSQLMGMH---QQIVPSQGQM----VQQQG-- 640 +S P + PQ+ P P + GM QQ+ P GQ QQG Sbjct: 483 QSSPYPGGSYG--PPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ 540 Query: 641 ---TLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQ--RMTPPK----------QMLS 685 + PQ P + +AQ +P P Q++ R PP ++ Sbjct: 541 PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ 600 Query: 686 QQGPQMMAPHNQMMG--PQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQI 743 Q+ P + + + P G + + T+ + + P + I Sbjct: 601 QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI 660 Query: 744 MRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPH-MAQQHG 802 GP+P+ G+ V SG + P P + P Q G Q + P S M Q+ G Sbjct: 661 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 720 Query: 803 DPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPN 862 A T N QM A G +G S H Sbjct: 721 FMAGTQRN----PQM-----------------AQYGPQQTGPSMSPH----------PSP 749 Query: 863 GNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRK 922 G QM G ++ Q S+G +G Q N +PP Sbjct: 750 GGQMHAG------------------ISSFQQSNSSGTYGPQMSQYGPQGN---YSRPPAY 788 Query: 923 KKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDN----SGPKLPEFSNRPPGYPSQPV 978 P +G P PG GI+ +N GP P + PS + Sbjct: 789 S-------GVPSASYSG-------PGPG-MGISANNQMHGQGPSQPCGAVPLGRMPSAGM 833 Query: 979 EQRPLQQMPPQLMQHVAPPPQPPQQQ-------PQPQLPQQQQPPPPSQPQSQQQQQQQQ 1031 + RP P M + P QQ P P + ++ Q + Q+ Q + Sbjct: 834 QNRPF----PGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR 889 Query: 1032 QMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQS--GSVPVMVSLQGPASV- 1088 Q M Q + P SQ P+N S M Q P MV+ ASV Sbjct: 890 QGSFPGMNQSGLMASSSPYSQ-------PMNNSSSLMNTQAPPYSMAPAMVN-SSAASVG 941 Query: 1089 ---PPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPG 1145 SP + ++P+ PL ++ ++ + +PQ S S ++ S+ S P Sbjct: 942 LADMMSPGESKLPL----PLKADGKE---EGTPQPESKS--------KDSYSSQGISQPP 986 Query: 1146 GPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQ 1205 P N+P PSP+S P S+ S HG ++++P Sbjct: 987 TPGNLPV-----------------PSPMS---------PSSASISSFHGDESDSISSP-- 1018 Query: 1206 TSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPER-LNASIAGLFPPQINIPLPPRP 1264 PKTP +SP+ T + T+ E+ PER L F + P+ P Sbjct: 1019 -GWPKTP--SSPKSSSSTTTGEK--ITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLP 1073 Query: 1265 NL-NRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKR 1323 + + D L + G A N AT S +S K+ Sbjct: 1074 AVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFA 1133 Query: 1324 ASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPR----NVLVSPT 1379 R P +T K PKL S N+ LQ + P+ N + Sbjct: 1134 FECKIERGEEPPPEVFST----GDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVP 1189 Query: 1380 PLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNI 1439 PP P S P+ Q S +V D +S ++S N+ Sbjct: 1190 GDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNA--------- 1240 Query: 1440 ELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSG 1499 P Q+ M +P+ + P +PNK P MR+ P S + Sbjct: 1241 -----PYQQ-GMSMPDVMGR---MPYEPNKDP---------FGGMRKVPGSSEPFMTQGQ 1282 Query: 1500 APNVTIK 1506 PN +++ Sbjct: 1283 MPNSSMQ 1289 Score = 49.3 bits (116), Expect = 4e-05 Identities = 89/347 (25%), Positives = 120/347 (34%), Gaps = 40/347 (11%) Query: 145 QDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQ 204 QD+ P GA +++ M G R + P P G S G P L Sbjct: 1289 QDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLY 1348 Query: 205 PRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQ 264 P+ P D M + H + Q N+ + P + Q Sbjct: 1349 PQQPNYKRHMDGM------YGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQ 1402 Query: 265 QQQQQQQQQQQQQQQQQQQ-----QQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWN 319 Q +++ Q Q Q Q+ P Q + PQ + + A +P P Sbjct: 1403 GQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQ--QNMWAARNDMPYPYQNR 1460 Query: 320 QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFG 379 Q P G Q PP G T +P Q++ Q PSH P+ Sbjct: 1461 QGPGGPTQAPPYPGMNRT-------DDMMVP---DQRINHES-----QWPSHVSQRQPYM 1505 Query: 380 SQQAS-QAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQ-QPHLTNK-SPASSPSSFQ 436 S AS Q T PQ P T P SL SR P+P Q L N+ SP+ SP Sbjct: 1506 SSSASMQPITRPPQ---PSYQTPP---SLPNHISRAPSPASFQRSLENRMSPSKSPFLPS 1559 Query: 437 QGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSS-PGRNPMVQQ 482 PTV T Q GP PPQ P+ + P S P+++Q Sbjct: 1560 MKMQKVMPTV-PTSQVTGP-PPQPPPIRREITFPPGSVEASQPVLKQ 1604 Score = 38.9 bits (89), Expect = 0.053 Identities = 160/775 (20%), Positives = 255/775 (32%), Gaps = 130/775 (16%) Query: 1083 QGPASVPPSPDKQ-RMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAP 1141 Q P+ P+ ++ P P+ G + + +P P S P ++ A+ A+G + Sbjct: 352 QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQA 411 Query: 1142 SVPGGPNN---------MPSHVVLPQNQLMMTGP-KPGPSPLSATQGATPQQPPVNSLPS 1191 + G P+ Q P PGP+ + +QG+ P P V P Sbjct: 412 AAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPT-MGRSQGS-PMDPMVMKRPQ 469 Query: 1192 SHGHHFPNVAAPTQTSRPKT-PNRASPRP---YYPQTPNNRPPSTEPSEISLSPERLNAS 1247 +G S P + P ++SP P Y P P P + R + Sbjct: 470 LYG----------MGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQG--------RTPGA 511 Query: 1248 IAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDS 1307 +AG+ PQ +P G+ QQG P Q P + P P Sbjct: 512 MAGMQYPQQQMPPQYGQQGVSGYCQQGQQPY----YSQQPQPPHLPPQAQYLP------- 560 Query: 1308 VVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTP-SPGRQNSKAPKLTLASQTNAALLQ 1366 S + +R P +R P +PG+ N + L L Q + L Sbjct: 561 ----------SQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHE--DLNLIQQERPSSLP 608 Query: 1367 NV-----ELPRNV------LVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDN 1415 ++ +LP VS + + S P S +P S + GG Sbjct: 609 DLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPS- 667 Query: 1416 KESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEE 1475 P S ++QSR ++ ++P ++ P QS+ P+ ++ P +E Sbjct: 668 ------PVGSPVGSNQSRSGPISPA--SIPGSQMPPQPPGSQSESSSHPA-LSQSPMPQE 718 Query: 1476 NKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQ 1535 + ++ R P + P T ++P G + Sbjct: 719 -RGFMAGTQRN--------------PQMAQYGPQQTGPSMSPHPSPGGQMHAGI------ 757 Query: 1536 DLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPN 1595 SS + SNS S P++S+ S PP S V S+S S P P Sbjct: 758 ---SSFQQSNS----------SGTYGPQMSQYGPQGNYSRPPAYSG-VPSASYSGPGPGM 803 Query: 1596 QITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSA----AQSNA 1651 I+ + S A + SA M N S S G S Sbjct: 804 GISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPP 863 Query: 1652 RPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSA 1711 P +++++Q S S + P SGLM S P++ ++ + A Sbjct: 864 MPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQA 923 Query: 1712 P--------VPPNALSSSPAPNIQTGR---PLVLSSRATPVQLPSPPCTSSPVVPSHPPV 1760 P V +A S A + G PL L + P P S S Sbjct: 924 PPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGIS 983 Query: 1761 QQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSK 1815 Q N SP +SA ++ +S ++ SP +P S + S + K Sbjct: 984 QPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTGEK 1038 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 102 bits (253), Expect = 5e-21 Identities = 258/1163 (22%), Positives = 389/1163 (33%), Gaps = 247/1163 (21%) Query: 200 NPELQPRTPRPA---SQSDAMDPLL----------SGLHIQQQS---HPSGSLAPPHHPM 243 +P + P TP P SQ MDP++ S H Q Q +P GS PP Sbjct: 440 HPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQR 499 Query: 244 QPVSVNRQ----MNPANFPQLQQQQQ----------QQQQQQQQQQQQQQQQQQQQLQAR 289 P+ + + M +PQ Q Q QQ QQ QQ Q Q Q Sbjct: 500 YPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL 559 Query: 290 PPQQHQQQQPQGIRPQ--FTAPTQVPVPPG------------------------WNQLPS 323 P Q Q+ QPQ Q + +Q P+ PG + LP+ Sbjct: 560 PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPT 619 Query: 324 GALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATV----------------- 366 G + S T++QG + P P A P L+++ Sbjct: 620 GTEATLSSAVSASGSTSSQGDQSNPAQSPFSP--HASPHLSSIPGGPSPSPVGSPVGSNQ 677 Query: 367 ---------QTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTP 417 P PP P GSQ S +H P +S Q PQ + G R P Sbjct: 678 SRSGPISPASIPGSQMPPQPPGSQSESSSH---PALS---QSPMPQERGFMAGTQRNPQM 731 Query: 418 LQQ-PHLT--NKSPASSP--------SSFQQGSPASSPTVNQTQQQMGP-----RPPQNN 461 Q P T + SP SP SSFQQ + SS T Q GP RPP + Sbjct: 732 AQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSN--SSGTYGPQMSQYGPQGNYSRPPAYS 789 Query: 462 PLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSA 521 +P S PG + N M Q P+Q P P LG MP SA Sbjct: 790 GVPSA---SYSGPGPGMGISANN------QMHGQGPSQ-PCGAVP-LGRMP-------SA 831 Query: 522 GQANPNFMQGQVPSTTATTPGNS-------GAPQLQANQNVQHAGGQGAGPPQNQMQVSH 574 G N F G + S T ++PG S G P N+ Q A N Q Sbjct: 832 GMQNRPF-PGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQ 890 Query: 575 GP-PNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQL------MGMHQQ 627 G P M Q LM + +S +L N Q P P+ + +G+ Sbjct: 891 GSFPGMNQSGLMASSSPYSQPMNNSS-----SLMNTQAPPYSMAPAMVNSSAASVGLADM 945 Query: 628 IVPSQGQMV-------QQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPP 680 + P + ++ +++GT P++ S + G+ + LG P+R Sbjct: 946 MSPGESKLPLPLKADGKEEGTPQPESKSKKSSSS-TTTGEKITK--VYELGNEPERKLWV 1002 Query: 681 KQMLS----QQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNV 736 + L+ + P P +G + L + +++I Q NK + + +N+ Sbjct: 1003 DRYLTFMEERGSPVSSLP---AVGKKPLDLFRLYVCVKEI-GGLAQVNKNKKWRELATNL 1058 Query: 737 MPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPH 796 G + +++ +Q+ ++ + P S + L+PP P+ Sbjct: 1059 NVGTSS---SAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANS 1115 Query: 797 MAQQHGD-PATTANNDVSLSQMMPDVSIQQTNMVPPHVQ--AMQGNSASGNHFSGHGMSF 853 + Q P +T +N S++++ D+ T PH Q MQG +S +S Sbjct: 1116 GSLQGPQTPQSTGSN--SMAEVPGDLK-PPTPASTPHGQMTPMQGGRSS-------TISV 1165 Query: 854 NAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANK 913 + PFS + + FP +T +P + D+ NK K Sbjct: 1166 HDPFSDVSDSS---------FPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRK 1216 Query: 914 PKKKKPP-----RKKKNSQQDLNTPDTRPA----GLEEADQPPLPGEQGINLDNSGPKLP 964 P + +S QD+ A G+ + Q P + G + P Sbjct: 1217 VPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYP 1276 Query: 965 EFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQ 1024 P G P Q L P +H+ PP ++ + + Q SQ Sbjct: 1277 G-QGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQY-------SSQ 1328 Query: 1025 QQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGP-------LNPDSQRMPMQQSGSVP 1077 QQ+ Q + P + P + +GP + P P+Q S S Sbjct: 1329 QQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEG 1388 Query: 1078 VMVSL-----------------QGPASVPPSPDKQRMP--MPVNTPLGSNSR--KMVYQE 1116 ++ GP PP P R M + + S+ V Q Sbjct: 1389 PQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQR 1448 Query: 1117 SPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGP------ 1170 P SS+ + + P+ S PS+P + PS ++ P P Sbjct: 1449 QPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMK 1508 Query: 1171 -------SPLSATQGATPQQPPV 1186 P S G PQ PP+ Sbjct: 1509 MQKVMPTVPTSQVTGPPPQPPPI 1531 Score = 80.9 bits (198), Expect = 1e-14 Identities = 234/1039 (22%), Positives = 347/1039 (33%), Gaps = 185/1039 (17%) Query: 317 GWNQLPSGAL--------QPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQT 368 G NQ PSGA P P S G AP P P Q Q QA + A Sbjct: 349 GQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAA-- 406 Query: 369 PSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSP 428 G QQA+ M +P + Q Q+ H P Sbjct: 407 ----------GGQQAAAGMGLGKDMGAQYAAASPAWAAAQ----------QRSH-----P 441 Query: 429 ASSPSS------FQQGSPASSPTVNQTQQQMG------PRPPQNNPLPQGFQQPVSSPGR 476 A SP + QGSP P V + Q G +P Q++P P G P P R Sbjct: 442 AMSPGTPGPTMGRSQGSP-MDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP-PGPQR 499 Query: 477 NPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPST 536 P+ QG P MQ PQ G+ G ++ + + Q P +P Sbjct: 500 YPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQP----PHLPPQ 555 Query: 537 TATTPGNSGAPQLQANQNVQHAG-GQGAGPPQNQMQVSHGPPNMMQ----PSLMGIHGNM 591 P S + Q Q++ G G + PP + +H N++Q SL + G++ Sbjct: 556 AQYLPSQS-QQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSI 614 Query: 592 NNQQAGT-----SGVPQVNLSNMQG---QPQQGPPSQLMGMHQQIVPS-------QGQMV 636 ++ GT S V ++ QG P Q P S H +P + Sbjct: 615 DDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVG 674 Query: 637 QQQGTLNPQNPMILSRAQLMPQ----GQMMVNPPSQNLGPSPQRM-----TPPKQMLSQQ 687 Q P +P + +Q+ PQ + P+ + P PQ T ++Q Sbjct: 675 SNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQY 734 Query: 688 GPQM----MAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPG---- 739 GPQ M+PH P GQ+ + + + Q+ Q + P Sbjct: 735 GPQQTGPSMSPH---PSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGV 791 Query: 740 PAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRP-PGPSPHMA 798 P+ GP P M + QM GQ Q P P M G RP PG M Sbjct: 792 PSASYSGPGPGMG---ISANNQMHGQGPSQ--PCGAVPLGRMPSAGMQNRPFPGNMSSMT 846 Query: 799 QQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHG------MS 852 P + + MP V+ + +QA NSA S G M+ Sbjct: 847 P--SSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQA-AANSAQSRQGSFPGMNQSGLMA 903 Query: 853 FNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNAN 912 ++P+S P N S P + +P +VN SA G+ + + + Sbjct: 904 SSSPYS-QPMNNSSSLMNTQAPPYS-----MAPAMVN-----SSAASVGLADMMSPGESK 952 Query: 913 KPKKKK----------PPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPK 962 P K P K K S T + E ++P E+ + +D Sbjct: 953 LPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEP----ERKLWVDRYLTF 1008 Query: 963 LPEFSNRPPGYPSQPVEQRPLQQMPPQL-MQHVAPPPQPPQQQPQPQLPQQQQPPPPSQP 1021 + E + P+ V ++PL + ++ + Q + + +L S Sbjct: 1009 MEERGSPVSSLPA--VGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSA 1066 Query: 1022 QSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNP-DSQRMPMQQSGSVPVMV 1080 S ++Q Q + + + + PP + D+++ P Q S Sbjct: 1067 ASSLKKQYIQYLF----------AFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSG 1116 Query: 1081 SLQGPA--------SVPPSPDKQRMPMPVNTP-------LGSNSRKMVYQESPQNPSSSP 1125 SLQGP S+ P + P P +TP G S + + + S S Sbjct: 1117 SLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSS 1176 Query: 1126 LAEMASL-PEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPK--PGPSPLSATQGATPQ 1182 + S+ P A + S+P MP N+ G + PG S TQG P Sbjct: 1177 FPKRNSMTPNAPYQQGMSMPDVMGRMP----YEPNKDPFGGMRKVPGSSEPFMTQGQMPN 1232 Query: 1183 QPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRAS----PRPYYPQTPNNRPPSTEPSEIS 1238 + S N+ R + P AS PY Q P PPS +P Sbjct: 1233 SSMQDMYNQSPSGAMSNLG---MGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGG 1289 Query: 1239 LSPERLNASIAGLFPPQIN 1257 P GL+P Q N Sbjct: 1290 HQP--------GLYPQQPN 1300 Score = 79.7 bits (195), Expect = 3e-14 Identities = 241/1056 (22%), Positives = 337/1056 (31%), Gaps = 201/1056 (19%) Query: 260 LQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWN 319 LQQQ Q QQQQQQQQQQQQQQQQQQ + G PQ + P G Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQHPI--SNNNSLGGAGGGAPQPGPDMEQPQHGGAK 105 Query: 320 QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR---PSLATVQTPSHPPPPY 376 +G PP G ++ + P M + R P L + T PP Sbjct: 106 DSAAGGQADPP-----GPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGT-QQPPVAV 159 Query: 377 PFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPA----SSP 432 P G + P+ +N AP GGP P H +SP S Sbjct: 160 PGGGGGPAAV----PEFNNYYGSAAP----ASGGPGGRAGPCFDQHGGQQSPGMGMMHSA 211 Query: 433 SSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVM 492 S+ G+P S + + + G Q N P G+ +P + G Sbjct: 212 SAAAAGAPGSMDPLQNSHE--GYPNSQCNHYP-GYSRPGAGGGGG--------------- 253 Query: 493 QQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQAN 552 G S G GG G AG A + + A G G Sbjct: 254 --GGGGGGGGSGGGGGGG-------GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY---- 300 Query: 553 QNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQ 612 GG AG G MM P G + +G GQ Sbjct: 301 ------GGSSAGYGVLSSPRQQGGGMMMGPG----GGGAASLSKAAAGSAAGGFQRFAGQ 350 Query: 613 PQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQ--NPMILSRAQLMPQGQMMVNPPS--- 667 Q PS Q++ S M++ G P+ +P PQ Q + Sbjct: 351 NQH--PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGG 408 Query: 668 ----------QNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVL--LQQNPMIEQ 715 +++G +P Q+ M+P G G + Q +PM Sbjct: 409 QQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP-----GTPGPTMGRSQGSPMDPM 463 Query: 716 IMTN-QMQGNKQQFNTQ-NQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPV 773 +M Q+ G ++Q QS+ PG + GP G + G M+G PQQ Sbjct: 464 VMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQ--- 520 Query: 774 NNSPSQV--MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPP 831 P Q G+ G + G P+ +QQ P +Q +P S Q+ Sbjct: 521 -QMPPQYGQQGVSGYCQQ--GQQPYYSQQPQPPHLPPQ-----AQYLPSQSQQR------ 566 Query: 832 HVQAMQGNSASGNHFSGHGMSFNAPFS-GAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNL 890 Q Q S G+G P + G PN ++ Q D++ + L Sbjct: 567 -YQPQQDMSQ-----EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTG 620 Query: 891 LQSDISAGHFGVNNKQNNTNANKPKKKK-PPRKKKNSQQDLNTPDTRPAGLEEADQPPLP 949 ++ +S+ + + + + P + P + P P G Sbjct: 621 TEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVG---------- 670 Query: 950 GEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQL 1009 G N SGP P P QMPPQ PP + P L Sbjct: 671 SPVGSNQSRSGPISP--------------ASIPGSQMPPQ------PPGSQSESSSHPAL 710 Query: 1010 PQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP-PRGPLNPD-SQR 1067 Q P P + Q+ QM Q P S + HP P G ++ S Sbjct: 711 ---SQSPMPQERGFMAGTQRNPQMAQYGPQQTGP-------SMSPHPSPGGQMHAGISSF 760 Query: 1068 MPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLA 1127 SG+ +S GP G+ SR Y P S P Sbjct: 761 QQSNSSGTYGPQMSQYGPQ-------------------GNYSRPPAYSGVPSASYSGPGP 801 Query: 1128 EMA-SLPEASGSEAPSVPGGP---NNMPS----HVVLPQNQLMMTGPKPGPSPLSATQGA 1179 M S + PS P G MPS + P N MT PG S G Sbjct: 802 GMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQ-QGGPGM 860 Query: 1180 TPQQPPVNSLPSSHGHHFPNVAAPTQTSRP-------KTPNRASPRPY-YPQTPNNRPPS 1231 P P VN AA + SR ++ AS PY P ++ + Sbjct: 861 GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMN 920 Query: 1232 TEPSEISLSPERLNASIAG------LFPPQINIPLP 1261 T+ S++P +N+S A + P + +PLP Sbjct: 921 TQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLP 956 Score = 77.8 bits (190), Expect = 1e-13 Identities = 200/927 (21%), Positives = 322/927 (34%), Gaps = 151/927 (16%) Query: 748 TPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATT 807 +P QG + G + ++ GQ P G +P + Q P+ Sbjct: 312 SPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPM 371 Query: 808 ANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMS 867 S P+ S PP Q +A A G Q + Sbjct: 372 MR---SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGA----------------AAGGQQAA 412 Query: 868 CGQNPGFPVNKDVTLTSPLLVNLLQSD---ISAGHFGVNNKQNNTNANKPKKKKPPR--- 921 G G + SP Q +S G G ++ + P K P+ Sbjct: 413 AGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYG 472 Query: 922 --KKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDN------SGPKLPEFSNRPPGY 973 +SQ ++P P G + PP P I + +G + P+ PP Y Sbjct: 473 MGSNPHSQPQQSSP--YPGG---SYGPPGPQRYPIGIQGRTPGAMAGMQYPQ-QQMPPQY 526 Query: 974 PSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQM 1033 Q V Q P Q PP PPQ Q P QSQQ+ Q QQ Sbjct: 527 GQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPS-------------QSQQRYQPQQD- 572 Query: 1034 MMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPD 1093 M Q+ R PP P P+ + + + Q + L G P+ Sbjct: 573 -----MSQEGYGTR------SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGT 621 Query: 1094 KQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSH 1153 + + V+ ++S Q NP+ SP + AS P S S+PGGP+ P Sbjct: 622 EATLSSAVSASGSTSS-----QGDQSNPAQSPFSPHAS-PHLS-----SIPGGPSPSPVG 670 Query: 1154 VVLPQNQLMMTGPKPGP-SPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTP 1212 + NQ + GP SP S P QPP + SS + A +Q+ P+ Sbjct: 671 SPVGSNQ-----SRSGPISPASIPGSQMPPQPPGSQSESS------SHPALSQSPMPQER 719 Query: 1213 NRASPRPYYPQTPNNRPPSTEPSEISLSPE-----RLNASI--------AGLFPPQINIP 1259 + PQ P T P S+SP +++A I +G + PQ++ Sbjct: 720 GFMAGTQRNPQMAQYGPQQTGP---SMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMS-Q 775 Query: 1260 LPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSG 1319 P+ N +R G+ + G + ++ +N Q V G+ ++G Sbjct: 776 YGPQGNYSRPPAYSGVPSASYSGPG---PGMGISANNQMHGQGPSQPCGAVPLGRMPSAG 832 Query: 1320 ATKRASPSNSRR---SSPGSSRKTTPSPG-------RQNSKAPKLTLASQTNAALLQNVE 1369 R P N SSPG S++ P G R+ +A + + N+A + Sbjct: 833 MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGS 892 Query: 1370 LP----RNVLVSPTPLANPPVPGSFPNNSG--LNPQNSTVSVAAVGGVVEDNKESLNVPQ 1423 P ++ S +P + P NNS +N Q S+A +V + S+ + Sbjct: 893 FPGMNQSGLMASSSPYSQP------MNNSSSLMNTQAPPYSMAP--AMVNSSAASVGL-- 942 Query: 1424 DSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDP-NKLPSVEENKNLVSP 1482 +D + K + + LKA +E PE +SKK + K+ V E N P Sbjct: 943 -ADMMSPGESK--LPLPLKA-DGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGN--EP 996 Query: 1483 AMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKE 1542 + ++ G+P ++ G L++ V +K+ + + +E Sbjct: 997 ERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVC---VKEIGGLAQVNKNKKWRE 1053 Query: 1543 PSNSLNLPHSNELCSSLVHPELS-----EVSSNVAPSIPPVM---SRPVSSSSISTPLPP 1594 + +LN+ S+ SSL + E PP + + P P Sbjct: 1054 LATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPA 1113 Query: 1595 NQITVFVTSNPITTSANTSAALPTHLQ 1621 N ++ P +T +N+ A +P L+ Sbjct: 1114 NSGSLQGPQTPQSTGSNSMAEVPGDLK 1140 Score = 62.8 bits (151), Expect = 3e-09 Identities = 215/1033 (20%), Positives = 334/1033 (32%), Gaps = 176/1033 (17%) Query: 106 ERLRILAQSNNQQLRDLG--ILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEA 163 E L ++ Q L DL I + E ++ A++ + S + + A + A Sbjct: 594 EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHA 653 Query: 164 GFPMASGPGIIRMNNPATVMIPPGGNVS-SSMMAPG--PNPELQPRTPRPASQSDAMDPL 220 ++S PG +P+ V P G N S S ++P P ++ P+ P S+S + L Sbjct: 654 SPHLSSIPG---GPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPAL 710 Query: 221 LSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQ 280 Q++ +G+ +P +Q P+ P Q QQ Sbjct: 711 SQSPMPQERGFMAGT---QRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 767 Query: 281 QQQQQLQARPPQQHQQQQP--QGI-RPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGT 337 Q+ PQ + + P G+ ++ P NQ+ P LG Sbjct: 768 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR 827 Query: 338 MTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQ----- 392 M + G + P PG M + P ++ P PP P +++A +A Q Sbjct: 828 MPS-AGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPP-MPTVNRKAQEAAAAVMQAAANS 885 Query: 393 -MSNPGQFTAPQMKSLQGGPSRVPTPLQQPHL---TNKSPASSPSSFQQGSPASSPTVNQ 448 S G F L S P+ T P S + S AS + Sbjct: 886 AQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADM 945 Query: 449 TQ--QQMGPRPPQNNPLPQGFQQPVSSPGRNP-----------MVQQGNVPPNFMVMQQ- 494 + P P + + +G QP S ++ + + GN P + + + Sbjct: 946 MSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRY 1005 Query: 495 ---QPPNQGPQSLHPGLGGMPKRLPPGF-------SAGQANPNFMQGQVPSTTATTPGNS 544 P S P +G P L + Q N N ++ + +S Sbjct: 1006 LTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSS 1065 Query: 545 GAPQLQANQNVQHAGG------QGAGPPQNQMQV--SHGPPNMMQPSLMG---IHGNMNN 593 A L+ Q +Q+ +G PP + P + PS + G Sbjct: 1066 AASSLK-KQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTP 1124 Query: 594 QQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMI-LSR 652 Q G++ + +V PP+ H Q+ P QG + T++ +P +S Sbjct: 1125 QSTGSNSMAEV-------PGDLKPPTPASTPHGQMTPMQGG---RSSTISVHDPFSDVSD 1174 Query: 653 AQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPM 712 + + M N P Q Q M+ P M G P+ G +V P Sbjct: 1175 SSFPKRNSMTPNAPYQ------QGMSMPDVM----GRMPYEPNKDPFGGMRKVPGSSEPF 1224 Query: 713 IEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQ---GNMVQFTGQMSGQMLPQ 769 + Q G + Q+ N P A G Q G + GQ P Sbjct: 1225 MTQ-------GQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPG 1277 Query: 770 QGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMV 829 QGP + P G + P HM +G PA D+ Q S QQ M Sbjct: 1278 QGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQY----SSQQQEMY 1333 Query: 830 PPHVQAMQGNSASGNHFSGHGMSFNAPFSGA-PNGNQMSCGQNPGFPVNKDVTLTSPLLV 888 + G +SG P G P Q PG + ++ Sbjct: 1334 NQY----------GGSYSGPD---RRPIQGQYPYPYSRERMQGPGQIQTHGIP--PQMMG 1378 Query: 889 NLLQSDISAGH----FGVNNK-----QNNTNANKPKKKKPPRKKKNSQQDLNTPDTR--- 936 LQS S G + N QN P + PP N D+ PD R Sbjct: 1379 GPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQA-PPYPGMNRTDDMMVPDQRINH 1437 Query: 937 -----------------PAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVE 979 A ++ +PP P Q + P LP +R P S Sbjct: 1438 ESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQ------TPPSLPNHISRAPSPASF--- 1488 Query: 980 QRPLQQ---------MPPQLMQHV----------APPPQPPQQQPQPQLPQQQQPPPPSQ 1020 QR L+ +P MQ V PPPQP P + ++ PP S Sbjct: 1489 QRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQP------PPIRREITFPPGSV 1542 Query: 1021 PQSQQQQQQQQQM 1033 SQ +Q++++ Sbjct: 1543 EASQPVLKQRRKI 1555 Score = 60.5 bits (145), Expect = 2e-08 Identities = 167/785 (21%), Positives = 249/785 (31%), Gaps = 162/785 (20%) Query: 429 ASSPSSFQQGSPASS--PTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVP 486 A+S S GS A Q Q G P N L S G P + P Sbjct: 329 AASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAP 388 Query: 487 PNFMVMQQQPPNQGPQSLHPGLG----------GMPKRLPPGFSAGQANPNFMQGQVPST 536 P PP PQS G GM G A+P + Q S Sbjct: 389 P--------PPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSH 440 Query: 537 TATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQA 596 A +PG G G+ G P + M M +P L G+ N ++Q Sbjct: 441 PAMSPGTPGPTM-----------GRSQGSPMDPMV-------MKRPQLYGMGSNPHSQPQ 482 Query: 597 GTSGVPQVNLSNMQGQPQQGP-------PSQLMGMH---QQIVPSQGQM----VQQQG-- 640 +S P + PQ+ P P + GM QQ+ P GQ QQG Sbjct: 483 QSSPYPGGSYG--PPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ 540 Query: 641 ---TLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQ--RMTPPK----------QMLS 685 + PQ P + +AQ +P P Q++ R PP ++ Sbjct: 541 PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ 600 Query: 686 QQGPQMMAPHNQMMG--PQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQI 743 Q+ P + + + P G + + T+ + + P + I Sbjct: 601 QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI 660 Query: 744 MRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPH-MAQQHG 802 GP+P+ G+ V SG + P P + P Q G Q + P S M Q+ G Sbjct: 661 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 720 Query: 803 DPATTANNDVSLSQMMPDVSIQQTN-MVPPH----------VQAMQGNSASGNH---FSG 848 A T N M QQT + PH + + Q +++SG + S Sbjct: 721 FMAGTQRN-----PQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQ 775 Query: 849 HGMSFN----APFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNN 904 +G N +SG P+ + G PG ++ NN Sbjct: 776 YGPQGNYSRPPAYSGVPSASY--SGPGPGMGIS------------------------ANN 809 Query: 905 KQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLP 964 + + ++P P + + AG++ P PG N+ + P P Sbjct: 810 QMHGQGPSQPCGAVPLGRMPS------------AGMQNR---PFPG----NMSSMTPSSP 850 Query: 965 EFSNR--PPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQ---QQQPPPPS 1019 S + P P P R Q+ +MQ A Q +Q P + Q P S Sbjct: 851 GMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ-SRQGSFPGMNQSGLMASSSPYS 909 Query: 1020 QPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVM 1079 QP + LM Q P P N + M +P+ Sbjct: 910 QPMNNSSS---------LMNTQAPPYSMAPAMVN----SSAASVGLADMMSPGESKLPLP 956 Query: 1080 VSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSE 1139 + G P P+ + +T G K VY+ + + + E GS Sbjct: 957 LKADGKEEGTPQPESKSKKSSSSTTTGEKITK-VYELGNEPERKLWVDRYLTFMEERGSP 1015 Query: 1140 APSVP 1144 S+P Sbjct: 1016 VSSLP 1020 >gi|50345997 E1A binding protein p300 [Homo sapiens] Length = 2414 Score = 101 bits (252), Expect = 7e-21 Identities = 168/632 (26%), Positives = 218/632 (34%), Gaps = 119/632 (18%) Query: 260 LQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQP-------------QGIRPQF 306 ++Q+ +QQQ Q + QQ Q +++ +Q QQ P Q PQ Sbjct: 1809 IKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQT 1868 Query: 307 TAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATV 366 PT P P N +P P + G ++ + + P P Q T Sbjct: 1869 PQPTSQPQPTPPNSMPPYL----PRTQAAGPVSQGKAAGQVTPPTPPQ----------TA 1914 Query: 367 QTPSHPPPPYPFG-SQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTN 425 Q P PPP + Q +A QM++ F P + P + P +T Sbjct: 1915 QPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTR 1974 Query: 426 KSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNV 485 PS + P PT QQ P P PQ Q + P + Q G Sbjct: 1975 -----GPSGHLE--PGMGPT---GMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHG-- 2022 Query: 486 PPNFMVMQQQPPNQGPQSLHPGLGGMP-KRLPPGFSAGQANPNFM-----------QGQV 533 QP N PQ PGLG + L PG + QA N + Q QV Sbjct: 2023 ---------QPLNMAPQ---PGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQV 2070 Query: 534 PSTTATTPGNSGAPQLQ-----ANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIH 588 S P A Q AN N Q GQ G PQ Q + PP M P G+H Sbjct: 2071 LSILHANPQLLAAFIKQRAAKYANSNPQPIPGQ-PGMPQGQPGLQ--PPTM--PGQQGVH 2125 Query: 589 GN--MNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQN 646 N M N +GV + G PQQ P QL + P QM T+ Q Sbjct: 2126 SNPAMQNMNPMQAGVQRA------GLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQF 2179 Query: 647 PMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQG-QV 705 IL R Q+M Q Q P +GP MA HNQ PQG Sbjct: 2180 RDILRRQQMMQQQQQQGAGP--GIGPG------------------MANHNQFQQPQGVGY 2219 Query: 706 LLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQ---GNMVQFTGQM 762 QQ ++ M QGN Q Q+ A + +Q G+ VQ M Sbjct: 2220 PPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQ-PNPM 2278 Query: 763 SGQ--MLPQQGPVNNSPSQVM--GIQGQVLRP---PGPSPHMAQQHGDPATTANNDVSLS 815 S Q MLP Q + Q + + QV P P P P H P+ S Sbjct: 2279 SPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPH 2338 Query: 816 QMMPDVSIQQTNMVPPHVQAMQGNSASGNHFS 847 + P QT+ P + A Q N HF+ Sbjct: 2339 HVSP-----QTSSPHPGLVAAQANPMEQGHFA 2365 Score = 89.7 bits (221), Expect = 3e-17 Identities = 142/578 (24%), Positives = 196/578 (33%), Gaps = 100/578 (17%) Query: 166 PMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNP---ELQPRTPRPASQSDAMDPLLS 222 P G + A + PP ++ PGP P E+ + R A M Sbjct: 1888 PRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQM----- 1942 Query: 223 GLHIQQQSHPSGSLAPPHHPMQPVSVN-RQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQ 281 H+Q P PP PM P+ +N M L+ QQQ Q Sbjct: 1943 -AHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLP 2001 Query: 282 QQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTAN 341 Q QQLQ+ P+ Q +P AP G + L G + Q L T+ Sbjct: 2002 QPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTL--- 2058 Query: 342 QGWKKAPLPGPMQQQ-----LQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNP 396 ++P P+QQQ L A P L F Q+A++ + PQ P Sbjct: 2059 ----RSP-SSPLQQQQVLSILHANPQLLAA-----------FIKQRAAKYANSNPQ-PIP 2101 Query: 397 GQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPA-SSPSSFQQGSPASSPTVNQTQQQMGP 455 GQ P QG P P + + +PA + + Q G + Q QQQ+ Sbjct: 2102 GQPGMP-----QGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQL-- 2154 Query: 456 RPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRL 515 +PP PQ Q ++ N M Q + + QQ Q Q PG+G Sbjct: 2155 QPPMGGMSPQAQQMNMN---HNTMPSQFR---DILRRQQMMQQQQQQGAGPGIG------ 2202 Query: 516 PPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHG 575 PG + Q Q Q V + PPQ Q ++ H Sbjct: 2203 -------------------------PGMANHNQFQQPQGVGY-------PPQQQQRMQHH 2230 Query: 576 PPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQ--LMGMHQQIVPSQG 633 M Q + MG G + +G Q Q G P Q M Q ++P+Q Sbjct: 2231 MQQMQQGN-MGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQA 2289 Query: 634 QMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMA 693 Q QG Q P LS PQ P SQ SP P+ PQ + Sbjct: 2290 QSPHLQG---QQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSS 2346 Query: 694 PHNQMMGPQGQVLLQ-------QNPMIEQIMTNQMQGN 724 PH ++ Q + Q QN M+ Q+ +N N Sbjct: 2347 PHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMAN 2384 Score = 65.5 bits (158), Expect = 5e-10 Identities = 143/602 (23%), Positives = 195/602 (32%), Gaps = 79/602 (13%) Query: 465 QGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQA 524 QG P + P QQ P Q P PQ P MP LP +AG Sbjct: 1845 QGLPSPTPATPTTPTGQQPTTP------QTPQPTSQPQPTPPN--SMPPYLPRTQAAGPV 1896 Query: 525 NPNFMQGQV-PSTTATT--PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQ--------VS 573 + GQV P T T P G P +Q Q A Q QM + Sbjct: 1897 SQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQI---QRAAETQRQMAHVQIFQRPIQ 1953 Query: 574 HGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQG 633 H P M + MG+ N G SG +P GP GM QQ SQG Sbjct: 1954 HQMPPMTPMAPMGM--NPPPMTRGPSG---------HLEPGMGPT----GMQQQPPWSQG 1998 Query: 634 QMVQ-QQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRM-TPPKQMLSQQGPQM 691 + Q QQ P ++S AQ M P +G SP + T +Q L + Sbjct: 1999 GLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTL 2058 Query: 692 MAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRG-PTPN 750 +P + + Q +L NP + Q N Q PG Q G P Sbjct: 2059 RSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPG-QPGMPQGQPGLQPPT 2117 Query: 751 MQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANN 810 M G + M P Q V + Q Q+ P G AQQ N+ Sbjct: 2118 MPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQ-----MNMNH 2172 Query: 811 DVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQ 870 + SQ D+ +Q Q MQ G +G G+ G N NQ Q Sbjct: 2173 NTMPSQFR-DILRRQ--------QMMQQQQQQG---AGPGIG-----PGMANHNQFQQPQ 2215 Query: 871 NPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDL 930 G+P + + + + G+ G + + +++ QQ + Sbjct: 2216 GVGYPPQQQQRMQHHM------QQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQM 2269 Query: 931 NTP-DTRPAGLEE---ADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQM 986 +P P ++ +Q P QG + NS L P PS + +P Sbjct: 2270 GSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNS---LSNQVRSPQPVPSPRPQSQPPHSS 2326 Query: 987 PPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSV 1046 P MQ P P P PQ P + P Q Q M+ + +P Sbjct: 2327 PSPRMQ---PQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMA 2383 Query: 1047 RL 1048 L Sbjct: 2384 NL 2385 Score = 65.1 bits (157), Expect = 7e-10 Identities = 119/542 (21%), Positives = 191/542 (35%), Gaps = 115/542 (21%) Query: 590 NMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQI---VPSQGQMVQQQGTLNPQN 646 N NQQ G S +SNM P MG++ + PS +N QN Sbjct: 490 NQQNQQPGQSPQGMRPMSNMSASP--------MGVNGGVGVQTPSLLSDSMLHSAINSQN 541 Query: 647 PMILSRAQLMPQGQM--------------------------MVNPPSQNLGPSPQRMTPP 680 PM+ A + G M +V+ Q + P+P P Sbjct: 542 PMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPD----P 597 Query: 681 KQMLSQQGPQMMAPHNQMMGPQGQVLLQQ----NPMIEQIMTNQMQGNKQQFNTQNQSNV 736 + ++ ++A ++ G + + + + E+I Q + +++ + N+ Sbjct: 598 AALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNM 657 Query: 737 MP---GPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGP 793 +P G + P PNM GQ PQ G +N P ++R G Sbjct: 658 LPNAAGMVPVSMNPGPNM------------GQ--PQPGMTSNGPLP----DPSMIR--GS 697 Query: 794 SPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSF 853 P+ P + N +S P + +QT + H Q Q + N G+G Sbjct: 698 VPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGAL--NPPMGYGPRM 755 Query: 854 NAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANK 913 P + G + Q P +N +P S+G V+ Q ++++ Sbjct: 756 QQPSN---QGQFLPQTQFPSQGMNVTNIPLAP----------SSGQAPVSQAQMSSSSCP 802 Query: 914 PKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGI---NLDNSGPKLPEFSNRP 970 P + S ++ P L + P+P + G + P + P Sbjct: 803 VNSPIMPPGSQGSH--IHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIP 860 Query: 971 PGYPSQPVEQRPLQQMPP-QLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQ 1029 P+ P MPP Q + PPP+ P QLPQQ QP P+ P + Q QQQ Sbjct: 861 APVPTPPA-------MPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQ 913 Query: 1030 QQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVP 1089 P+S + + +V P PL P P+ Q VS++G S P Sbjct: 914 -------------PRS-QQSTAASVPTPTAPLLPPQPATPLSQPA-----VSIEGQVSNP 954 Query: 1090 PS 1091 PS Sbjct: 955 PS 956 Score = 63.5 bits (153), Expect = 2e-09 Identities = 97/384 (25%), Positives = 131/384 (34%), Gaps = 74/384 (19%) Query: 160 RMEAGFPMASGPGIIRMNNPATVMIPPG-GNVSSSMMAPGPNPE--LQP--RTPRPASQS 214 ++++G P + + + P + PG G V S + PG + LQ RT R S Sbjct: 2005 QLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSP 2064 Query: 215 DAMDPLLSGLHIQQQ---------------SHPSGSLAPPHHP-----MQPVSVNRQMNP 254 +LS LH Q S+P P P +QP ++ Q Sbjct: 2065 LQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGV 2124 Query: 255 ANFPQLQQQQQQQQQQQQQQQQQQQQQQQ------------QQLQ-------------AR 289 + P +Q Q Q+ QQQ QQQ QQ+ R Sbjct: 2125 HSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILR 2184 Query: 290 PPQQHQQQQPQGIRP----------QFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMT 339 Q QQQQ QG P QF P V PP Q +Q QG++G + Sbjct: 2185 RQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQ-QMQQGNMGQI- 2242 Query: 340 ANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQF 399 G L LQA Q P P P QQ P + Sbjct: 2243 ---GQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHM-----LPNQAQSPHL 2294 Query: 400 TAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQ-QMGPRPP 458 Q+ + R P P+ P ++ P SSPS Q P+ QT G Sbjct: 2295 QGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAA 2354 Query: 459 QNNPLPQGFQQPVSSPGRNPMVQQ 482 Q NP+ QG +SP +N M+ Q Sbjct: 2355 QANPMEQGH---FASPDQNSMLSQ 2375 Score = 58.5 bits (140), Expect = 6e-08 Identities = 142/635 (22%), Positives = 199/635 (31%), Gaps = 129/635 (20%) Query: 530 QGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIH- 588 Q +PS T TP Q Q PQ Q PPN M P L Sbjct: 1844 QQGLPSPTPATPTTPTGQQPTTPQT-----------PQPTSQPQPTPPNSMPPYLPRTQA 1892 Query: 589 -GNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNP 647 G ++ +A P Q P GPP + M QI + Q Q P Sbjct: 1893 AGPVSQGKAAGQVTPPTPPQTAQ-PPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRP 1951 Query: 648 MILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLL 707 + + P M +NPP GPS + P MGP G + Sbjct: 1952 IQHQMPPMTPMAPMGMNPPPMTRGPSGH----------------LEPG---MGPTG---M 1989 Query: 708 QQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRG-PTPNMQGNMVQFTGQMSGQM 766 QQ P Q +P P Q+ G P P M Sbjct: 1990 QQQPPWSQ-------------------GGLPQPQQLQSGMPRPAMMS------------- 2017 Query: 767 LPQQG-PVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQ 825 + Q G P+N +P +G G PG A Q+ T + S Q +SI Sbjct: 2018 VAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQN--LLRTLRSPSSPLQQQQVLSILH 2075 Query: 826 TN--MVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLT 883 N ++ ++ A+ N P G P Q G P + + Sbjct: 2076 ANPQLLAAFIKQRAAKYANSNP---------QPIPGQPGMPQGQPGLQPPTMPGQQGVHS 2126 Query: 884 SPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEA 943 +P + N+ G+ +Q P P+ ++ + P L Sbjct: 2127 NPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQ 2186 Query: 944 DQPPLPGEQGINLDNSGPKL-PEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQ 1002 +QG +GP + P +N Q V P QQ Q MQH Q Sbjct: 2187 QMMQQQQQQG-----AGPGIGPGMANHNQFQQPQGVGYPPQQQ---QRMQHHMQQMQQGN 2238 Query: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLN 1062 QLPQ + Q+ QQ+ QQQM PV N P+ + Sbjct: 2239 MGQIGQLPQALGAEAGASLQAYQQRLLQQQMGS-------------PVQPNPMSPQQHML 2285 Query: 1063 PDSQRMPMQQSGSVPVMVSLQ--GPASVP------------PSPDKQRMPMPVNTPLGSN 1108 P+ + P Q +P +S Q P VP PSP Q P P + ++ Sbjct: 2286 PNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTS 2345 Query: 1109 SRKMVYQESPQNP----------SSSPLAEMASLP 1133 S + NP +S L+++AS P Sbjct: 2346 SPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNP 2380 Score = 56.2 bits (134), Expect = 3e-07 Identities = 89/338 (26%), Positives = 118/338 (34%), Gaps = 41/338 (12%) Query: 183 MIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHP-----SGSLA 237 M+P + M PGPN QP+ P S DP + + Q P SG Sbjct: 657 MLPNAAGMVPVSMNPGPNMG-QPQ-PGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQ 714 Query: 238 PPHHPM-QPVSVNRQMNPA-NFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ 295 M QP V RQ P + QL Q + QQ Q Q L PQ Sbjct: 715 FGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFL----PQTQF 770 Query: 296 QQQPQGIRPQFTAPTQVPVPPGWNQLPSGA------LQPPPAQGSLGTMTANQGWKKAPL 349 Q + AP+ P Q+ S + + PP +QGS L Sbjct: 771 PSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGS--------HIHCPQL 822 Query: 350 PGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQG 409 P P Q P + TP H PP G+QQ P + P PQ ++L Sbjct: 823 PQPALHQNSPSPVPSRTPTPHHTPPS--IGAQQPPATTIPAPVPTPPAMPPGPQSQALHP 880 Query: 410 GPSRVPTP--LQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGF 467 P + PTP Q P S ++PS+ Q P P Q+ P P LP Sbjct: 881 PPRQTPTPPTTQLPQQVQPSLPAAPSADQ---PQQQPRSQQSTAASVPTPTA-PLLPPQP 936 Query: 468 QQPVSSPGRNPMVQQGNVPP------NFMVMQQQPPNQ 499 P+S P + Q N P N + ++ P+Q Sbjct: 937 ATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQ 974 Score = 54.3 bits (129), Expect = 1e-06 Identities = 222/1088 (20%), Positives = 347/1088 (31%), Gaps = 208/1088 (19%) Query: 190 VSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVN 249 ++ +++ PGP +P+ PA + A D GSL H + +N Sbjct: 1 MAENVVEPGPPSAKRPKLSSPALSASASD-----------GTDFGSLFDLEHDLPDELIN 49 Query: 250 R-QMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTA 308 ++ N + Q Q Q + +Q + + + P + Sbjct: 50 STELGLTNGGDINQLQTSLGMVQDAASKHKQLSELLRSGSSP----------NLNMGVGG 99 Query: 309 PTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQT 368 P QV + S A Q P G + +M + +A L P + P+ Q+ Sbjct: 100 PGQV--------MASQAQQSSPGLGLINSMVKSP-MTQAGLTSPNMGMGTSGPNQGPTQS 150 Query: 369 PSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQG--------GPSRVPTPLQQ 420 P +Q A +T NPG A + + G R +Q Sbjct: 151 TGMMNSPV---NQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGRQNMQY 207 Query: 421 PHLTNKSPASSPSS-FQQGSPASSPTVNQTQQQMGPRPPQ-------NNPLPQGFQ---- 468 P+ S + + QQGSP Q Q G R PQ NNP P G Sbjct: 208 PNPGMGSAGNLLTEPLQQGSP-------QMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQN 260 Query: 469 --QPVSSPGRNPMVQ-----QGNVPPNFMVMQQQP----PNQG----PQSLHPGLGGMPK 513 Q + + G +Q N+ P M + P PN G PQ PGL P Sbjct: 261 PGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLV-TPV 319 Query: 514 RLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQM--- 570 G A A+P + + + QAN V+ +N + Sbjct: 320 AQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 379 Query: 571 ---------QVSHGPPNMMQ------------PSLMGIH--GNMNNQQAGTSGVPQVNLS 607 QV+H + P + + G+ NQQ +G P V L Sbjct: 380 THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAP-VGLG 438 Query: 608 NMQ--GQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNP 665 N G QQ P+ + QI PS + L P +++ PQ Q N Sbjct: 439 NPSSLGVGQQSAPN--LSTVSQIDPSSIERAYAALGL----PYQVNQMPTQPQVQAK-NQ 491 Query: 666 PSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNK 725 +Q G SPQ M P M + MG G V +Q ++ M + ++ Sbjct: 492 QNQQPGQSPQGMRPMSNMSASP-----------MGVNGGVGVQTPSLLSDSMLHSAINSQ 540 Query: 726 QQFNTQNQSNVMPGPAQIMRGP-------------TPNMQGNMVQFTGQMSGQMLPQQGP 772 ++N S GP P T +++ ++V ++ + P P Sbjct: 541 NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVH---KLVQAIFPTPDP 597 Query: 773 VNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPD------------ 820 ++ + + + GD +ANN ++ + Sbjct: 598 AALKDRRMENLVA----------YARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEK 647 Query: 821 --VSIQQTNMVPPHVQAMQGNSASGNHFSGH--GMSFNAPF-------SGAPNGNQMSCG 869 +Q+ NM+P + + G + GM+ N P PN Sbjct: 648 RRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRIT 707 Query: 870 QNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQD 929 G +++ P +V + H G + A P PR ++ S Q Sbjct: 708 PQSGLNQFGQMSMAQPPIVPRQTPPLQ--HHG---QLAQPGALNPPMGYGPRMQQPSNQG 762 Query: 930 LNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQ--MP 987 P T+ P QG+N+ N P P P P+ MP Sbjct: 763 QFLPQTQ-----------FPS-QGMNVTNI-PLAPSSGQAPVSQAQMSSSSCPVNSPIMP 809 Query: 988 PQLM-QHVAPP--PQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPK 1044 P H+ P PQP Q P + P P P S QQ + + P Sbjct: 810 PGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPA-PVPTPPA 868 Query: 1045 SVRLPVSQNVHPP-RGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNT 1103 P SQ +HPP R P + ++P Q S+P S P P S +P T Sbjct: 869 MPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPT 928 Query: 1104 PLGSNSRKMVYQESPQNPSSSPLAEM---ASLPEASGSEAPSVPGGPNNMPSHVVLPQNQ 1160 + P P S P + S P ++ S + PS V + + Sbjct: 929 -------APLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAK 981 Query: 1161 LMMTGPKP 1168 + + P+P Sbjct: 982 MEVDQPEP 989 Score = 53.1 bits (126), Expect = 3e-06 Identities = 113/506 (22%), Positives = 171/506 (33%), Gaps = 104/506 (20%) Query: 971 PGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQ----------------- 1013 P P+ P Q+P PQ P P PP P P LP+ Q Sbjct: 1852 PATPTTPTGQQPTTPQTPQPTSQ--PQPTPPNSMP-PYLPRTQAAGPVSQGKAAGQVTPP 1908 Query: 1014 ------QPPPPSQP--------QSQQQQQQQQQMMMM------LMMQQDPKSVRLPVSQN 1053 QPP P P Q Q+ + Q+QM + + Q P + P+ N Sbjct: 1909 TPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMN 1968 Query: 1054 VHP----PRGPLNP-----DSQRMPMQQSGSVPVMVSLQG----PASVPPSPDKQRM--- 1097 P P G L P Q+ P G +P LQ PA + + Q + Sbjct: 1969 PPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMA 2028 Query: 1098 PMPVNTPLGSNSRK--MVYQESPQN------PSSSPLAEMASLPEASGSEAPSVPGGPNN 1149 P P +G + K V Q++ QN SSPL + L + P Sbjct: 2029 PQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVL--------SILHANPQL 2080 Query: 1150 MPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRP 1209 + + + + + P+P P QG QPP ++P G H N A Sbjct: 2081 LAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPP--TMPGQQGVH-SNPAMQNMNPMQ 2137 Query: 1210 KTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRG 1269 RA PQ +P +SP+ ++ P + R + + Sbjct: 2138 AGVQRAGLPQQQPQ------QQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQ 2191 Query: 1270 FDQQGLNPTTLKAIG-----QAPSNLTMNPSNFATPQTHKLDSVVVNSGK--------QS 1316 QQG P + Q P + P Q H N G+ + Sbjct: 2192 QQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGA 2251 Query: 1317 NSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPR---N 1373 +GA+ +A + GS + P +Q+ L +Q + LQ ++P N Sbjct: 2252 EAGASLQAYQQRLLQQQMGSPVQPNPMSPQQH------MLPNQAQSPHLQGQQIPNSLSN 2305 Query: 1374 VLVSPTPLANPPVPGSFPNNSGLNPQ 1399 + SP P+ +P P S P +S +P+ Sbjct: 2306 QVRSPQPVPSPR-PQSQPPHSSPSPR 2330 Score = 52.0 bits (123), Expect = 6e-06 Identities = 112/479 (23%), Positives = 159/479 (33%), Gaps = 105/479 (21%) Query: 1048 LPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGS 1107 +PVS N P G P M +G +P P+ + S Q MP + G Sbjct: 665 VPVSMNPGPNMGQPQPG-----MTSNGPLP------DPSMIRGSVPNQMMPR-ITPQSGL 712 Query: 1108 NS-RKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPN-NMPSHV--VLPQNQLMM 1163 N +M + P P +P + G+ P + GP PS+ LPQ Q Sbjct: 713 NQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPS 772 Query: 1164 TGPKPGPSPLSATQGATPQQP--------PVNSL---PSSHGHHFPNVAAPTQTSRPKTP 1212 G PL+ + G P PVNS P S G H P +P Sbjct: 773 QGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSP 832 Query: 1213 NRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINI--PLPPRPNLNRGF 1270 SP P TP++ PP SI PP I P+P P + G Sbjct: 833 ---SPVPSRTPTPHHTPP----------------SIGAQQPPATTIPAPVPTPPAMPPGP 873 Query: 1271 DQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSR 1330 Q L+P P TP T +L V Q + A A + Sbjct: 874 QSQALHPP---------------PRQTPTPPTTQLPQQV-----QPSLPAAPSADQPQQQ 913 Query: 1331 RSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSF 1390 S S+ + P+P T SQ ++ V +NPP S Sbjct: 914 PRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQV-------------SNPPSTSST 960 Query: 1391 P-NNSGLNPQNSTVSVAAVGGVVEDNKESLNV-PQD------SDCQNSQSRKEQVNIELK 1442 N+ + + + V + D E + P+D DC+ + E+ + ELK Sbjct: 961 EVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELK 1020 Query: 1443 AVPAQEVKMVVPEDQSKKDGQPSDP------NKLPSVEENKNLVSPAM----REAPTSL 1491 +E EDQ S P K+ EE + + P + R+ P SL Sbjct: 1021 TEIKEE------EDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESL 1073 Score = 47.4 bits (111), Expect = 1e-04 Identities = 56/234 (23%), Positives = 83/234 (35%), Gaps = 42/234 (17%) Query: 1675 PSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVL 1734 PS PA P TT +G P + P PQ P PPN++ P Q P+ Sbjct: 1848 PSPTPATP-TTPTGQQPTTPQTPQPTSQPQ-------PTPPNSMPPY-LPRTQAAGPVSQ 1898 Query: 1735 SSRATPVQLPSPPCTSSPVVPSHPP--------VQQVKELNPDEASPQVNTSADQNTLPS 1786 A V P+PP T+ P +P PP +Q+ E A Q+ Q+ +P Sbjct: 1899 GKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMP- 1957 Query: 1787 SQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQY 1846 T ++P+ N P + + G TG ++ Sbjct: 1958 --PMTPMAPMGMNPPPMTRGPSGHLEPGMGP------------------TGMQQQPPWSQ 1997 Query: 1847 GADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTAS 1900 G + + P +M Q L+ P P L ++ SP+ PGT S Sbjct: 1998 GGLPQPQQLQSGMPRPAMMSVAQHGQPLN----MAPQPGLGQVGISPLKPGTVS 2047 Score = 47.4 bits (111), Expect = 1e-04 Identities = 72/297 (24%), Positives = 96/297 (32%), Gaps = 105/297 (35%) Query: 177 NNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQ--QQSHPSG 234 +NP + PG + P P Q PA Q+ M+P+ +G+ Q P Sbjct: 2095 SNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQN--MNPMQAGVQRAGLPQQQPQQ 2152 Query: 235 SLAPPHHPMQPVSVNRQMNPANFP----------QLQQQQQQQ----------------- 267 L PP M P + MN P Q+ QQQQQQ Sbjct: 2153 QLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQ 2212 Query: 268 ---------QQQQQQQQQQQQQQQ-----------------------------QQQL--- 286 QQQQ+ Q QQ QQ QQQ+ Sbjct: 2213 QPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSP 2272 Query: 287 -QARP--PQQHQ------------QQQPQGIRPQFTAPTQVPVPPGWNQ----LPSGALQ 327 Q P PQQH QQ P + Q +P VP P +Q PS +Q Sbjct: 2273 VQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQ 2332 Query: 328 PPPAQGSLGTMTAN--------------QGWKKAPLPGPMQQQLQARPSLATVQTPS 370 P P+ + T++ QG +P M QL + P +A + S Sbjct: 2333 PQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGAS 2389 Score = 42.4 bits (98), Expect = 0.005 Identities = 151/697 (21%), Positives = 232/697 (33%), Gaps = 131/697 (18%) Query: 1160 QLMMTGPKPG---PSPLSATQGATPQQPPVNSL-PSSHGHHFPNVAAPTQTSRPKTPNRA 1215 Q ++TG G PS L Q + P V+ + PSS + + P Q ++ T + Sbjct: 427 QPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQV 486 Query: 1216 SPRPYYPQTPNNRPPSTEP-SEISLSPERLNASIAGLFPPQINIPL--------PPRPNL 1266 + Q P P P S +S SP +N + P ++ + P + Sbjct: 487 QAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSE 546 Query: 1267 NRGFDQQGLNPT-----TLKAIGQAPSNLTMNPSNFATPQTHKL--------DSVVVNSG 1313 N G PT T Q ++T + N HKL D + Sbjct: 547 NASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLV---HKLVQAIFPTPDPAALKDR 603 Query: 1314 KQSNSGATKRA------SPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQN 1367 + N A R +N+R + ++ + + L Q +L N Sbjct: 604 RMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQN---MLPN 660 Query: 1368 VELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDC 1427 V ++P P P PG N +P + + G V + PQ Sbjct: 661 AAGMVPVSMNPGPNMGQPQPGMTSNGPLPDP-------SMIRGSVPNQMMPRITPQSGLN 713 Query: 1428 QNSQSRKEQVNIELKAVP--------AQEVKMVVPEDQSKKDGQPSDPNK-LPSVE---E 1475 Q Q Q I + P AQ + P + QPS+ + LP + + Sbjct: 714 QFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQ 773 Query: 1476 NKNL----VSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVI 1531 N+ ++P+ +AP S +Q+ +S N I PPG + P + Sbjct: 774 GMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQ--------- 824 Query: 1532 PTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTP 1591 P L S S PS + PH P + + + V PP M P S + Sbjct: 825 PALHQNSPSPVPSRT-PTPHHTPPSIGAQQPPATTIPAPV--PTPPAM--PPGPQSQALH 879 Query: 1592 LPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNA 1651 PP Q T P TT LP +Q +L + SA Q Sbjct: 880 PPPRQ-----TPTPPTTQ------LPQQVQPSLPA----------------APSADQPQQ 912 Query: 1652 RPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSA 1711 +P+ SQ ST + P T + L+PP A PL P Sbjct: 913 QPR------------------SQQSTAASVP-TPTAPLLPPQPAT--PLSQPAVSIEGQV 951 Query: 1712 PVPPNALSSS-PAPNIQTGRPLVLSSRATPVQLPSP-PCTSSPVVPSHPPVQQVK--ELN 1767 PP+ S+ + I +P +++ P P + P S V+ K Sbjct: 952 SNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTE 1011 Query: 1768 PDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSS 1804 +E S ++ T + S S T SP +PG S Sbjct: 1012 TEERSTELKTEIKEEEDQPSTSATQSSP----APGQS 1044 Score = 38.5 bits (88), Expect = 0.069 Identities = 76/319 (23%), Positives = 109/319 (34%), Gaps = 53/319 (16%) Query: 998 PQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPP 1057 P P P QQ P QP SQ Q M L Q PVSQ Sbjct: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQ----AAGPVSQG--KA 1901 Query: 1058 RGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQES 1117 G + P + Q P +++ + + + QR V R + +Q Sbjct: 1902 AGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQI----FQRPIQHQMP 1957 Query: 1118 PQNPSSSPLAEMASLPEASGSEAPSVPG-GPNNMP-----SHVVLPQNQLMMTGPKPGPS 1171 P P +P+ M P G PG GP M S LPQ Q + +G P P+ Sbjct: 1958 PMTP-MAPMG-MNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSG-MPRPA 2014 Query: 1172 PLSATQGATP----QQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNN 1227 +S Q P QP + + S P P S + Sbjct: 2015 MMSVAQHGQPLNMAPQPGLGQVGIS----------------PLKPGTVSQQALQNLLRTL 2058 Query: 1228 RPPSTEPSE------ISLSPERLNASI---AGLFPPQINIPLPPRPNLNRGFDQQGLNPT 1278 R PS+ + + +P+ L A I A + P+P +P + +G Q GL P Sbjct: 2059 RSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQG--QPGLQPP 2116 Query: 1279 TL---KAIGQAPSNLTMNP 1294 T+ + + P+ MNP Sbjct: 2117 TMPGQQGVHSNPAMQNMNP 2135 Score = 33.5 bits (75), Expect = 2.2 Identities = 35/149 (23%), Positives = 56/149 (37%), Gaps = 21/149 (14%) Query: 1675 PSTIPAAPLTTNSGLMPPSVAVVGP--LHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPL 1732 P +P P + L PP P +PQ ++ S P P+A P Sbjct: 866 PPAMPPGP--QSQALHPPPRQTPTPPTTQLPQQVQ-PSLPAAPSADQPQQQPR------- 915 Query: 1733 VLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELN------PDEASPQVNTSADQNTLPS 1786 S ++T +P+P P P+ P Q + P +S +VN+ A P Sbjct: 916 --SQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQP- 972 Query: 1787 SQSTTMVSPLLTNSPGSSGNRRSPVSSSK 1815 SQ M + + + P + + +S SK Sbjct: 973 SQEVKMEAKMEVDQPEPADTQPEDISESK 1001 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 101 bits (251), Expect = 9e-21 Identities = 174/721 (24%), Positives = 247/721 (34%), Gaps = 118/721 (16%) Query: 140 AQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPP--GGNVSSSMMAP 197 AQ RS M+ P +G + A P S P M+ + P G N S P Sbjct: 353 AQQRSHHAPMS-PGSSGGGGQPLARTPQPSSP----MDQMGKMRPQPYGGTNPYSQQQGP 407 Query: 198 GPNPEL------QP---RTPR--PASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPV 246 P+ QP +TP+ P + + GL QQ P G P + Q Sbjct: 408 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQ 467 Query: 247 S--VNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRP 304 + N+Q P QQQQ QQ Q Q QQQ Q++PPQ Q P +P Sbjct: 468 TPYYNQQS-----PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP 522 Query: 305 QFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLA 364 Q P P + S Q P +Q + + P QQQ +P+ + Sbjct: 523 SQPPHQQSPAP--YPSQQSTTQQHPQSQ---------PPYSQPQAQSPYQQQQPQQPAPS 571 Query: 365 TVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQ-------FTAPQMKSLQGGPSRVPTP 417 T+ + P P SQQ + + FP Q +AP M S +GG + Sbjct: 572 TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631 Query: 418 LQQ-----PHLT---NKSPASSPSSFQQG---SPASSPTVNQTQQQMGPRPPQNNPLPQG 466 LQ P L+ + P + + G S SS Q+ P P +P G Sbjct: 632 LQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPG 691 Query: 467 FQ----QPVSSPGRNPMVQQGNVPPNFMVMQQQPP----NQGPQSLHPGLGGMPKRLPPG 518 + PV SP + G + P + Q PP Q +HP + G Sbjct: 692 IRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRG 751 Query: 519 FSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPN 578 + Q NP Q+P ++ PG++ +P+ Q +GGQ H Sbjct: 752 YM--QRNP-----QMPQYSSPQPGSALSPR-------QPSGGQ-----------IHTGMG 786 Query: 579 MMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQ 638 Q + MG +G Q G P+ N P PS M + + GQM Q Sbjct: 787 SYQQNSMGSYGPQGGQYGPQGGYPR--QPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ 844 Query: 639 QGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQM 698 G + P + R G P N+ P Q G M P M Sbjct: 845 PG-IPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------------QVGSGMCPPPGGM 890 Query: 699 MGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVM-PGPAQIMRGPTPNMQGNMVQ 757 Q+ + + N +Q + NQ +M GP G N M+ Sbjct: 891 -----NRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPY---GQGINSMAGMIN 942 Query: 758 FTG---QMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSL 814 G M G M + SP ++MG+ L P + A G P T + + S Sbjct: 943 PQGPPYSMGGTMANNSAGMAASP-EMMGLGDVKLTPATKMNNKAD--GTPKTESKSKKSS 999 Query: 815 S 815 S Sbjct: 1000 S 1000 Score = 99.0 bits (245), Expect = 4e-20 Identities = 223/970 (22%), Positives = 339/970 (34%), Gaps = 181/970 (18%) Query: 937 PAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYP--SQPVEQRPLQQMPPQLMQHV 994 P+G + Q P +Q + + P +S +PP +QP Q+ Q PPQL Sbjct: 459 PSGYGQQGQTPYYNQQS---PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQ 515 Query: 995 AP----PPQPPQQQ-----PQPQLPQQQQP---PPPSQPQSQQ--QQQQQQQMMMMLMMQ 1040 P P QPP QQ P Q QQ P PP SQPQ+Q QQQQ QQ + Q Sbjct: 516 PPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQ 575 Query: 1041 -------QDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQG--------- 1084 Q +S + SQ PP L+ DS Q+ S P M S +G Sbjct: 576 QAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG---SQASSAPSMTSSKGGQEDMNLSL 632 Query: 1085 ---PASVPP-SPDKQRMPMPVN---TPLGSNSRKMVYQESPQNPSSSPLAEMAS--LPEA 1135 P+S+P S +PM +P S S Q NP+ SP + S LP Sbjct: 633 QSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGI 692 Query: 1136 SGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVN--SLPSSH 1193 G +PS G P ++ P + + G + P P S Q + P +N S+ Sbjct: 693 RG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG-QSDSIMHPSMNQSSIAQDR 750 Query: 1194 GHHFPNVAAPTQTSRPKTPNRASPR-PYYPQTPNNRPPSTEPSEISLSPERLNASIAGLF 1252 G+ N P Q S P+ + SPR P Q + S S P+ G + Sbjct: 751 GYMQRNPQMP-QYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGY 809 Query: 1253 PPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNS 1312 P Q N P N G+NP + A GQ + P P Sbjct: 810 PRQPNYNALPNANYPSAGMAGGINP--MGAGGQMHGQPGIPPYGTLPP------------ 855 Query: 1313 GKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPR 1372 G+ S++ R N P P PG N K + +A A +QN Sbjct: 856 GRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGY 915 Query: 1373 NVLVSPTPLANPPVPGSFPNNSG--LNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNS 1430 + + P G N+ +NPQ S +GG + +N + Sbjct: 916 PNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYS---MGGTMANNSAGM----------- 961 Query: 1431 QSRKEQVNI-ELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPT 1489 + E + + ++K PA ++ +K DG P E+K+ S + Sbjct: 962 AASPEMMGLGDVKLTPATKM-------NNKADGTPK--------TESKSKKSSSSTTTNE 1006 Query: 1490 SLSQLLDNSGAPNVTI-----------KPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLS 1538 +++L + G P + K G+T+L P V + L + +++++ Sbjct: 1007 KITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNL----PAVGRKPLDLYRLYVSVKEIG 1062 Query: 1539 SS---------KEPSNSLNLPHSNELCSSLVHPELS---------EVSSNVAPSIPPVMS 1580 +E + +LN+ S+ SSL + E + P I Sbjct: 1063 GLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAAD 1122 Query: 1581 RPVSSSSISTPLPPNQITVFVTSNPITTSAN----------TSAALPTHLQSALMSTVVT 1630 S I P P ++ P +TS++ T A+ P H Q + + Sbjct: 1123 SKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTP-HSQIPPLPGMSR 1181 Query: 1631 MPNAGSKVMVSEGQSAAQSNARPQFITPVF---INSSSIIQVMK--------GSQPSTIP 1679 + G + ++G + P + +N+S ++ M GS Sbjct: 1182 SNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPG 1241 Query: 1680 AAPLTT-----NSGLMPPSVAVVGP----------LHIPQNIKFSSAPVPPNALSSSPAP 1724 + P + N G+ P GP H P + P P Sbjct: 1242 SDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGI---GPEG 1298 Query: 1725 NIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPP-VQQVKELNPDEASPQVNTSADQNT 1783 N+ TG P P +PS P + +PP QQ ++ D Q +T + Sbjct: 1299 NMSTGAP-------QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSG 1351 Query: 1784 LP-SSQSTTM 1792 P SQ TTM Sbjct: 1352 SPFPSQQTTM 1361 Score = 96.7 bits (239), Expect = 2e-19 Identities = 268/1206 (22%), Positives = 403/1206 (33%), Gaps = 221/1206 (18%) Query: 181 TVMIPPGGNVSSS------------MMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQ 228 T IPP G S +P P + P + +P SQ+ P S Q Sbjct: 448 TQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQP--SYQQQPQ 505 Query: 229 QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQ------QQQQQQQQQQQ 282 P + P + QP Q +PA +P Q QQ Q Q Q Q QQQQ Sbjct: 506 SQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQP 565 Query: 283 QQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQ 342 QQ + QQ QPQ + Q TA +Q PP +L + + S +MT+++ Sbjct: 566 QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPP-QELSQDSFGSQAS--SAPSMTSSK 622 Query: 343 GWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQA-------SQAHTNFPQMSN 395 G ++ M LQ+RPS ++ S P G++ A S ++ + SN Sbjct: 623 GGQE-----DMNLSLQSRPS--SLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSN 675 Query: 396 PGQ-----FTAPQMKSLQG-GPSRVPTP--LQQPHLTNKSPASSPSSFQQGSPASS---- 443 P Q T+P + ++G PS V +P + Q SPA+ P + P S Sbjct: 676 PAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDS 735 Query: 444 ---PTVNQTQ-------QQMGPRPPQ-NNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVM 492 P++NQ+ Q P+ PQ ++P P P G G+ N M Sbjct: 736 IMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGS 795 Query: 493 QQQPPNQ-GPQSLHP---GLGGMPK-RLPPGFSAGQANPNFMQGQ------VPSTTATTP 541 Q GPQ +P +P P AG NP GQ +P P Sbjct: 796 YGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPP 855 Query: 542 GN------SGAPQLQANQNVQHAGGQGAGPPQNQMQ--------VSH-----------GP 576 G P N+ G G PP M H G Sbjct: 856 GRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGY 915 Query: 577 PNMMQPSLMGI---HGNMNNQQAGTSGV--PQVNLSNMQGQPQQGPPS--QLMGMHQ-QI 628 PNM Q +MG +G N AG P ++ G + ++MG+ ++ Sbjct: 916 PNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKL 975 Query: 629 VPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQG 688 P+ + GT ++ S + ++ LG P+R + L+ Sbjct: 976 TPATKMNNKADGTPKTESKSKKSSSSTTTNEKIT---KLYELGGEPERKMWVDRYLAFTE 1032 Query: 689 PQMMAPHN----------------QMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQ----- 727 + M N + G + +N ++ TN G Sbjct: 1033 EKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSL 1092 Query: 728 ----------FNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSP 777 F + + P P + Q + + SG M Q P + S Sbjct: 1093 KKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSS 1152 Query: 778 SQVMGIQGQVLRPPGPS--PHMAQQHGDPATTANNDVSLSQMMPDVS---IQQTNMVPPH 832 S +G L+PP P+ PH +Q P + +N V + D S Q+ N + P+ Sbjct: 1153 SMA---EGGDLKPPTPASTPH-SQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPN 1208 Query: 833 --------VQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNP----GFPVNKDV 880 M G + + +G AP S MS GQ P G P ++ Sbjct: 1209 PGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDP----FMSSGQGPNGGMGDPYSR-- 1262 Query: 881 TLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGL 940 P L N+ +G + T +P + Q P +G+ Sbjct: 1263 -AAGPGLGNVAMGPRQHYPYGGPYDRVRT---EPGIGPEGNMSTGAPQPNLMPSNPDSGM 1318 Query: 941 EEADQ-PPLPGEQGINLDNSGPKLPEFSNRPPG--YPSQPVEQRPLQQMP---------- 987 + PP +Q +S P G +PSQ QQ Sbjct: 1319 YSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYG 1378 Query: 988 PQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVR 1047 P +H P Q Q QQQ PP QP SQQQ Q + + Sbjct: 1379 PPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPAT 1438 Query: 1048 LPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQR--MPMPVNTPL 1105 + P GP N + P Q + S PP + Q+ P + P+ Sbjct: 1439 ATAATERRPAGGPQN----QFPFQFG---------RDRVSAPPGTNAQQNMPPQMMGGPI 1485 Query: 1106 GSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMT- 1164 +++ V Q+ + + + +++G S P GP H V ++++ T Sbjct: 1486 QASAE--VAQQGTMWQGRNDMTYNYANRQSTG----SAPQGP---AYHGVNRTDEMLHTD 1536 Query: 1165 ------------GPKPGPSPLSATQGATPQQPPVN-SLPSSHGHHFPNVAAPTQTSRPKT 1211 G + P SA + PP N P S +H P V++P RP Sbjct: 1537 QRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRP-M 1595 Query: 1212 PNRASP 1217 NR SP Sbjct: 1596 ENRTSP 1601 Score = 63.9 bits (154), Expect = 2e-09 Identities = 123/555 (22%), Positives = 189/555 (34%), Gaps = 83/555 (14%) Query: 972 GYPSQPVEQRPLQQMPPQLMQHVAPPP----QPPQQQPQPQLPQQQQPPPPSQPQSQQQQ 1027 G QP+ + P P M + P P P QQ P QQ P QP Q Sbjct: 368 GGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427 Query: 1028 QQQQQMMMMLMMQQDPKSVR--LPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGP 1085 Q+ + MQ +S L +Q + PP G P Q G P Sbjct: 428 QRYP-----MTMQGRAQSAMGGLSYTQQI-PPYGQQGPSGYG----QQGQTPYYNQQS-- 475 Query: 1086 ASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPG 1145 P P +Q+ P P + + YQ+ PQ S P + + P + P Sbjct: 476 ----PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ--SQPPQLQSSQPPYSQQPSQPPHQQ 529 Query: 1146 GPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQ 1205 P PS Q P P S Q PQQP ++L Q Sbjct: 530 SPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQ-------------Q 576 Query: 1206 TSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPN 1265 + P+ ++ S + Y Q PP E S+ S + +A P + + + Sbjct: 577 AAYPQPQSQQSQQTAYSQ--QRFPPPQELSQDSFGSQASSA-------PSMTSSKGGQED 627 Query: 1266 LNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRAS 1325 +N + P++L + + +L M +P + + G+QSN A Sbjct: 628 MNLSLQSR---PSSLPDLSGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNP-----AQ 678 Query: 1326 PSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPP 1385 S +SP PSP S A +Q+ + L +P N + PP Sbjct: 679 SPFSPHTSPHLPGIRGPSPSPVGSPAS----VAQSRSGPLSPAAVPGNQM--------PP 726 Query: 1386 VPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNS------QSRKEQVNI 1439 P S ++S ++P + S+A G ++ N + +PQ S Q Q Q++ Sbjct: 727 RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ---MPQYSSPQPGSALSPRQPSGGQIHT 783 Query: 1440 ELKAVPAQEVKMVVPE--DQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSL---SQL 1494 + + + P+ + G P PN + N N S M + Q+ Sbjct: 784 GMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNY--NALPNANYPSAGMAGGINPMGAGGQM 841 Query: 1495 LDNSGAPNVTIKPPG 1509 G P PPG Sbjct: 842 HGQPGIPPYGTLPPG 856 Score = 63.9 bits (154), Expect = 2e-09 Identities = 155/683 (22%), Positives = 226/683 (33%), Gaps = 178/683 (26%) Query: 372 PPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKS------LQGGPSRVPTPLQQPH--- 422 PP + + SQ P + G PQ +GG + PTP PH Sbjct: 1114 PPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQI 1173 Query: 423 -----LTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRN 477 ++ + +F GS ++ Q + M P P G+Q P N Sbjct: 1174 PPLPGMSRSNSVGIQDAFNDGSDSTF----QKRNSMTPNP--------GYQ-----PSMN 1216 Query: 478 PMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLP---PGFSAGQANPNFMQGQVP 534 G + PN+ P G ++ P P S+GQ PN G P Sbjct: 1217 TSDMMGRM--------SYEPNKDPY-------GSMRKAPGSDPFMSSGQ-GPNGGMGD-P 1259 Query: 535 STTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQ 594 + A PG G + Q+ + G P ++++ G +G GNM Sbjct: 1260 YSRAAGPG-LGNVAMGPRQHYPYGG------PYDRVRTEPG---------IGPEGNM--- 1300 Query: 595 QAGTSGVPQVNLSNMQGQPQQGP------PSQLMGMHQQIVPSQGQMVQQQGTLNPQNPM 648 ++G PQ NL M P G P Q QQ S G QGT P Sbjct: 1301 ---STGAPQPNL--MPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGT--PSGSP 1353 Query: 649 ILSRAQLMPQGQMM--VNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVL 706 S+ M Q Q P GP +R +G P++ QGQ Sbjct: 1354 FPSQQTTMYQQQQQNYKRPMDGTYGPPAKR---------HEGEMYSVPYST---GQGQPQ 1401 Query: 707 LQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQM 766 QQ P + +Q Q P P Q N GN T + + Sbjct: 1402 QQQLPPAQPQPASQQQA------------AQPSPQQ----DVYNQYGNAYPATATAATER 1445 Query: 767 LPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQT 826 P GP N P Q + +V PPG + AQQ+ P QMM IQ + Sbjct: 1446 RPAGGPQNQFPFQFG--RDRVSAPPGTN---AQQNMPP-----------QMMGG-PIQAS 1488 Query: 827 NMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPL 886 V A QG G + M++N N+ S G P P V T Sbjct: 1489 AEV-----AQQGTMWQGR----NDMTYN-------YANRQSTGSAPQGPAYHGVNRTD-- 1530 Query: 887 LVNLLQSDISAGH-------------FGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTP 933 +L +D A H +G + P +PP +N +++P Sbjct: 1531 --EMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSP 1588 Query: 934 DTRPAGLEEADQPPLPG--EQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLM 991 P +E P G+ + +GP + P+ + P+Q PP + Sbjct: 1589 APLPRPMENRTSPSKSPFLHSGMKMQKAGPPV----------PASHIAPAPVQ--PPMIR 1636 Query: 992 QHVAPPPQPPQQQPQPQLPQQQQ 1014 + + PP + QP L Q+++ Sbjct: 1637 RDITFPP-GSVEATQPVLKQRRR 1658 Score = 58.5 bits (140), Expect = 6e-08 Identities = 98/407 (24%), Positives = 131/407 (32%), Gaps = 79/407 (19%) Query: 154 GAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQ 213 G G + M + A+GPG+ + P GG PG PE T P Sbjct: 1249 GQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPN 1308 Query: 214 SDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQ 273 +P SG +P +P PQ QQQQQQ+ Sbjct: 1309 LMPSNP------------DSGMYSPSRYP---------------PQQQQQQQQRHDSYGN 1341 Query: 274 QQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQ---FTAPTQ------VPVPPGWNQLPSG 324 Q Q ++ +QQQQ RP + P + VP Q Sbjct: 1342 QFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQ 1401 Query: 325 ALQPPPAQGSLGTMTANQGWKKAPLPGPMQ----QQLQARPSLATVQTPSHPPP------ 374 Q PPAQ A+Q ++A P P Q Q A P+ AT T P Sbjct: 1402 QQQLPPAQ----PQPASQ--QQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQF 1455 Query: 375 PYPFGSQQAS-----QAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPA 429 P+ FG + S A N P G A + QG + + + +S Sbjct: 1456 PFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTG 1515 Query: 430 SSPS-------------------SFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQP 470 S+P + +GS S T P PP P P +Q P Sbjct: 1516 SAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPP 1575 Query: 471 VSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPP 517 S P V P M + P++ P LH G+ M K PP Sbjct: 1576 PSMQNHIPQVSSPAPLPRPM-ENRTSPSKSP-FLHSGM-KMQKAGPP 1619 Score = 50.4 bits (119), Expect = 2e-05 Identities = 243/1158 (20%), Positives = 377/1158 (32%), Gaps = 207/1158 (17%) Query: 106 ERLRILAQSNNQQLRDLG--ILSVQIEGEGAINLALAQN--RSQDVRMNGPMGAGNSVRM 161 E + + QS L DL I + + EGA++ ++ + S + P + S Sbjct: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685 Query: 162 EAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDA-MDPL 220 P GP + +PA+V G +S + + P ++ PR P + QSD+ M P Sbjct: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAV---PGNQMPPRPP--SGQSDSIMHPS 740 Query: 221 LSGLHIQQ-----QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQ------ 269 ++ I Q Q +P P + QP S P+ Q+ QQ Sbjct: 741 MNQSSIAQDRGYMQRNPQ---MPQYSSPQPGSALSPRQPSG-GQIHTGMGSYQQNSMGSY 796 Query: 270 --QQQQQQQQQQQQQQQQLQARPPQQHQQQ------QPQGIRPQFTAPTQVP----VPPG 317 Q Q Q +Q A P + P G Q +P +PPG Sbjct: 797 GPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPG 856 Query: 318 WNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPS--HPPPP 375 ++ ++ P ++ M G P PG M ++ Q V S + PP Sbjct: 857 --RMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPG 914 Query: 376 YPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSF 435 YP Q T P G + M + QG P + + + A+SP Sbjct: 915 YP-NMNQGGMMGTGPPY--GQGINSMAGMINPQGPPYSMGGTMAN---NSAGMAASPEMM 968 Query: 436 QQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQ- 494 G +P + G P + + ++ + + G P M + + Sbjct: 969 GLGDVKLTPATKMNNKADGT-PKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRY 1027 Query: 495 ----QPPNQGPQSLHPGLGGMPKRLPPGFSA-------GQANPNFMQGQVPSTTATTPGN 543 + G +L P +G P L + + Q N N ++ + + Sbjct: 1028 LAFTEEKAMGMTNL-PAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSS 1086 Query: 544 SGAPQLQANQNVQHAGG------QGAGPPQNQMQVSHGP---PNMMQPSLMGIHGNMNNQ 594 S A L+ Q +Q +G PP + + P + PS G G+M Sbjct: 1087 SAASSLK-KQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAG-SGSMQGP 1144 Query: 595 QAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVP----SQGQMVQQQGTLNPQNPMIL 650 Q PQ S+M PP+ H QI P S+ V Q N Sbjct: 1145 QT-----PQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDG----- 1194 Query: 651 SRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQN 710 S + + M NP Q P G P+ G +++ Sbjct: 1195 SDSTFQKRNSMTPNPGYQ----------PSMNTSDMMGRMSYEPNKDPYGS-----MRKA 1239 Query: 711 PMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQ 770 P + M++ QG PG + GP Q P Sbjct: 1240 PGSDPFMSSG-QGPNGGMGDPYSRAAGPGLGNVAMGPR----------------QHYPYG 1282 Query: 771 GPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVP 830 GP + +V PG P G P +L PD + + P Sbjct: 1283 GPYD-----------RVRTEPGIGPEGNMSTGAPQP------NLMPSNPDSGMYSPSRYP 1325 Query: 831 PHVQAMQG--NSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLV 888 P Q Q + + GN FS G +PF QN P+ D T P Sbjct: 1326 PQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPM--DGTYGPP--- 1380 Query: 889 NLLQSDISAGHFG-VNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPP 947 + H G + + +T +P+ QQ L +PA ++A QP Sbjct: 1381 -------AKRHEGEMYSVPYSTGQGQPQ-----------QQQLPPAQPQPASQQQAAQPS 1422 Query: 948 LPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPL----QQMPPQL-MQHVAPPPQPPQ 1002 P + N ++ N P + E+RP Q P Q V+ PP Sbjct: 1423 -PQQDVYN---------QYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNA 1472 Query: 1003 QQPQPQLPQQQQPPPPSQPQSQQQ----QQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPR 1058 QQ P PQ P + + QQ Q + Q + + P V+ Sbjct: 1473 QQNMP--PQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTD 1530 Query: 1059 GPLNPD-------------SQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPL 1105 L+ D +++ P S VP M + P++ P P Q V++P Sbjct: 1531 EMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPM-TRPPPSNYQPPPSMQNHIPQVSSP- 1588 Query: 1106 GSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTG 1165 R M E+ +PS SP + +G P VP + P+ V P + +T Sbjct: 1589 APLPRPM---ENRTSPSKSPFLHSGMKMQKAG---PPVPAS-HIAPAPVQPPMIRRDITF 1641 Query: 1166 PKPGPSPLSATQGATPQQ 1183 P P + ATQ Q+ Sbjct: 1642 P---PGSVEATQPVLKQR 1656 Score = 47.4 bits (111), Expect = 1e-04 Identities = 93/425 (21%), Positives = 131/425 (30%), Gaps = 69/425 (16%) Query: 901 GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPL------PGEQGI 954 G+ + N+ + + +K+ Q +NT D E ++ P PG Sbjct: 1186 GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPF 1245 Query: 955 NLDNSGPK--LPEFSNRPPGYPSQPVEQRPLQQMP---PQLMQHVAPPPQP--------P 1001 GP + + +R G V P Q P P P P P Sbjct: 1246 MSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAP 1305 Query: 1002 QQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQ-------------------MMMMLMMQQD 1042 Q P P P P QQQQQQQ+ M QQ Sbjct: 1306 QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQ 1365 Query: 1043 PKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMP-- 1100 ++ + P+ PP + +P P L P S + P P Sbjct: 1366 QQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQ 1425 Query: 1101 -VNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPN---NMPSHVV- 1155 V G+ + + P+ P P G + S P G N NMP ++ Sbjct: 1426 DVYNQYGNAYPATATAATERRPAGGP---QNQFPFQFGRDRVSAPPGTNAQQNMPPQMMG 1482 Query: 1156 --------LPQNQLMMTGPKPGPSPLSATQ--GATPQQPPVNSLPSSHGHHFPNVAAPTQ 1205 + Q M G + Q G+ PQ P + + + + A + Sbjct: 1483 GPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHE 1542 Query: 1206 TSRPKTPNRASP-RPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLP-PR 1263 S P R P P P P RPP PS P N PQ++ P P PR Sbjct: 1543 GSWPSHGTRQPPYGPSAPVPPMTRPP---PSNYQPPPSMQN------HIPQVSSPAPLPR 1593 Query: 1264 PNLNR 1268 P NR Sbjct: 1594 PMENR 1598 Score = 33.9 bits (76), Expect = 1.7 Identities = 76/410 (18%), Positives = 134/410 (32%), Gaps = 52/410 (12%) Query: 1532 PTLQDLSSSKEPSNSLNLPHSNELCSSLVHPEL------SEVSSNVAPSIPPVMSRPVSS 1585 P+ Q S+ P + P ++ S H + + ++ P P S+P + Sbjct: 498 PSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQ 557 Query: 1586 SSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQS 1645 S P P ++ + AA P T + +S+ Sbjct: 558 SPYQQQQP---------QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608 Query: 1646 AAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAA-------PLTTNSGLMPPSVAVVG 1698 +Q+++ P + + + S+PS++P P+ T G + P V+ G Sbjct: 609 GSQASSAPSMTSSK--GGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE-GALSPGVSTSG 665 Query: 1699 PLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHP 1758 + Q + + A P + +S P I+ P + S A+ Q S P + + V + Sbjct: 666 -ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQM 724 Query: 1759 PVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKG 1818 P + + P +N S+ Q + + PGS+ + R P G Sbjct: 725 PPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTG 784 Query: 1819 KVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAP----------GLMGTE 1868 + + GS QYG G Q P G + Sbjct: 785 ---------MGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPM 835 Query: 1869 QLSTELDSKTPTPPAPTL-------LKMTSSPVGPGTASAGPSLPGGALP 1911 ++ + PP TL M + P GP A+ P + G P Sbjct: 836 GAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCP 885 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 100 bits (250), Expect = 1e-20 Identities = 97/283 (34%), Positives = 114/283 (40%), Gaps = 32/283 (11%) Query: 226 IQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQ 285 +QQQ L HH Q +Q QLQ QQQQQQQQQQQQQQQQ Q Q Sbjct: 210 LQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPP 269 Query: 286 LQARPPQQHQQQQPQGIRPQFTAP---TQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQ 342 +Q +PP Q Q P PQ TQ PP Q P A Q P+Q + T Sbjct: 270 IQ-QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA-QNQPSQLPPQSQTQPL 327 Query: 343 GWKKAPLPGPMQQQLQARPSLATVQTPS--HPPPPYPFGSQQASQAHT-NFPQMSNPG-- 397 + LPG Q L +P L V+ P PP P QQ + T QM PG Sbjct: 328 VSQAQALPG---QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQ 384 Query: 398 --QFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGP 455 Q + P + S P+P QQ P S Q G P+S P N + GP Sbjct: 385 VSQSSLPMLSS--------PSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSS---GP 433 Query: 456 RPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPN 498 P ++ LP QP SP P NF V P N Sbjct: 434 APSPSSFLPSPSPQPSQSP------VTARTPQNFSVPSPGPLN 470 Score = 92.0 bits (227), Expect = 5e-18 Identities = 130/457 (28%), Positives = 169/457 (36%), Gaps = 84/457 (18%) Query: 142 NRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSS-----SMMA 196 N+ ++ PM A S+ G P A GI +PP G S S+ A Sbjct: 71 NKKSQASVSDPMNALQSL---TGGPAAGAAGI---------GMPPRGPGQSLGGMGSLGA 118 Query: 197 PGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPAN 256 G +P S S P SG+ + S + +Q V++ +Q Sbjct: 119 MG----------QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQ 168 Query: 257 FPQLQQQQQQQQQQQQQQQQQQQQQ--QQQQLQARPPQQ---HQQQQPQGIRPQFTAPTQ 311 F Q QQ QQQQQQQQQQQ Q QQ QQQ QA QQ QQQQ Q + Q Sbjct: 169 FQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQ 228 Query: 312 VPVPPGWNQLPSGA---LQPPPAQGSLGTMTANQGWK-KAPLPGPMQQQLQARPSLATVQ 367 + QL A LQ Q Q + + P+ P QQ Q PS A Q Sbjct: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQ 288 Query: 368 -------TPSHPPPPYPFGSQQASQAHTNFPQMSN-----------PGQ--FTAPQMKSL 407 T H PPP P A + P S PGQ +T P +K + Sbjct: 289 QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFV 348 Query: 408 QGGPSRVPTPLQQPHLTNKSPA-SSPSSFQQGSPA-----------SSPTVNQTQQ--QM 453 + P V P QP + + A + + Q +P SSP+ Q Q Q Sbjct: 349 R-APMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQS 407 Query: 454 GPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPK 513 P PPQ +P P QP S P N P +F+ P+Q P + Sbjct: 408 MPPPPQPSPQP---GQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSP---------VTA 455 Query: 514 RLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQ 550 R P FS P PS+ + G+S A + Q Sbjct: 456 RTPQNFSVPSPGP-LNTPVNPSSVMSPAGSSQAEEQQ 491 Score = 68.2 bits (165), Expect = 8e-11 Identities = 83/340 (24%), Positives = 118/340 (34%), Gaps = 34/340 (10%) Query: 497 PNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQ-NV 555 P +GP G+G + P +GQ P G P + A + QLQ Q + Sbjct: 102 PPRGPGQSLGGMGSLGAMGQPMSLSGQPPPG-TSGMAPHSMAVVSTATPQTQLQLQQVAL 160 Query: 556 QHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQ 615 Q Q Q Q + Q M Q V Q Q Q QQ Sbjct: 161 QQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ---FQAVVQQQQQLQQQQQQQ 217 Query: 616 GPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQ 675 +L +QQ + Q Q +Q+ L Q + Q Q Q + P P Q Sbjct: 218 QHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQ 277 Query: 676 RMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSN 735 PP Q L QQ QM + PQ Q P + Q +Q+ Q +Q+ Sbjct: 278 PQPPPSQALPQQLQQMHHTQHHQPPPQ-----PQQPPVAQNQPSQLPPQSQTQPLVSQAQ 332 Query: 736 VMPG-------PAQIMRGPT--------PNMQGNMVQFTGQMSGQMLP-------QQGPV 773 +PG P + +R P P +Q + QM+ P+ Sbjct: 333 ALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPM 392 Query: 774 NNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVS 813 +SPS +Q PP P P + Q G P++ N++VS Sbjct: 393 LSSPSPGQQVQTPQSMPPPPQP--SPQPGQPSSQPNSNVS 430 Score = 65.5 bits (158), Expect = 5e-10 Identities = 86/341 (25%), Positives = 123/341 (36%), Gaps = 37/341 (10%) Query: 976 QPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMM 1035 Q +Q+ QQ +Q Q Q Q Q QQQ Q Q QQQQQQQQ ++ Sbjct: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLI 221 Query: 1036 MLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQ 1095 L Q+ + ++ Q + L Q+ QQ + Q P PP Q Sbjct: 222 KL-HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL-QAQPPIQQPPMQQPQ 279 Query: 1096 RMPMPVNTPLGSNSRKMVYQESPQNPSSSPLA--EMASLPEASG-----SEAPSVPGGPN 1148 P + + P P P+A + + LP S S+A ++PG Sbjct: 280 PPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPG--- 336 Query: 1149 NMPSHVVLPQNQLMMTGP--KPGPSPLSATQGATPQQPPVNSLPSS--HGHHFPNVAAPT 1204 Q++ T P K +P+ Q P QP V ++ VA Sbjct: 337 -----------QMLYTQPPLKFVRAPMVVQQ--PPVQPQVQQQQTAVQTAQAAQMVAPGV 383 Query: 1205 QTSRPKTPNRASPRP-YYPQTPNNRPPSTEPSEISLSPE---RLNASIAGLFPPQINIPL 1260 Q S+ P +SP P QTP + PP +PS P N S P +P Sbjct: 384 QVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS 443 Query: 1261 P-PRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATP 1300 P P+P+ + P P N +NPS+ +P Sbjct: 444 PSPQPSQS---PVTARTPQNFSVPSPGPLNTPVNPSSVMSP 481 Score = 60.8 bits (146), Expect = 1e-08 Identities = 101/438 (23%), Positives = 147/438 (33%), Gaps = 87/438 (19%) Query: 919 PPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPV 978 PPR S + + + + QPP PG G+ + + Sbjct: 102 PPRGPGQSLGGMGSLGAMGQPMSLSGQPP-PGTSGMAPHSMAVVSTATPQTQLQLQQVAL 160 Query: 979 EQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQ---QQQPPPPSQPQSQQQQQQQQQMMM 1035 +Q+ QQ Q Q Q QQQ Q Q Q QQQ Q Q Q QQQQQQQ + Sbjct: 161 QQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHL 220 Query: 1036 MLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQ 1095 + + Q+ + ++ Q + L Q+ QQ + + Q P PP Q Sbjct: 221 IKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA-QPPIQQPPMQQPQ 279 Query: 1096 RMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEM--ASLPEASG-----SEAPSVPGGPN 1148 P + + P P P+A+ + LP S S+A ++PG Sbjct: 280 PPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPG--- 336 Query: 1149 NMPSHVVLPQNQLMMTGPKPGPSPLSATQGA-TPQQPPVNSLPSSH------GHHFPNVA 1201 Q++ T P PL + QQPPV VA Sbjct: 337 -----------QMLYTQP-----PLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVA 380 Query: 1202 APTQTSRPKTPNRASPRP-YYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL 1260 Q S+ P +SP P QTP + PP +PS Sbjct: 381 PGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPS------------------------- 415 Query: 1261 PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPS----------------NFATPQTHK 1304 P+P Q P + + G APS + PS NF+ P Sbjct: 416 -PQPG------QPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGP 468 Query: 1305 LDSVVVNSGKQSNSGATK 1322 L++ V S S +G+++ Sbjct: 469 LNTPVNPSSVMSPAGSSQ 486 Score = 47.8 bits (112), Expect = 1e-04 Identities = 104/479 (21%), Positives = 149/479 (31%), Gaps = 88/479 (18%) Query: 556 QHAGGQGA-GPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQ 614 Q GG G+ G M +S PP P G+ + + ++ PQ L Q Q Sbjct: 108 QSLGGMGSLGAMGQPMSLSGQPP----PGTSGMAPH--SMAVVSTATPQTQLQLQQVALQ 161 Query: 615 QGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSP 674 Q Q QQ Q Q QQQ Q + + Q + Q Q + Sbjct: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQ---------- 211 Query: 675 QRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQS 734 +Q QQ + NQ Q Q LQ+ ++ Q Q +QQ Q Q Sbjct: 212 ------QQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ---QQQ- 261 Query: 735 NVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPS 794 Q ++ P Q M Q PQ P P Q+ + P P Sbjct: 262 -------QALQAQPPIQQPPMQQ----------PQPPPSQALPQQLQQMHHTQHHQPPPQ 304 Query: 795 PHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFN 854 P P N SQ+ P QT + QA+ G Sbjct: 305 PQ------QPPVAQNQP---SQLPPQ---SQTQPLVSQAQALPG---------------- 336 Query: 855 APFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKP 914 QM Q P V + + P + +Q +A + Sbjct: 337 ----------QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVS 386 Query: 915 KKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYP 974 + P + Q + TP + P + + QP P Q + +SGP S P P Sbjct: 387 QSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS--P 444 Query: 975 SQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQM 1033 S Q P+ PQ +P P P + P SQ + QQ + +Q+ Sbjct: 445 SPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVM----SPAGSSQAEEQQYLDKLKQL 499 Score = 41.2 bits (95), Expect = 0.011 Identities = 82/403 (20%), Positives = 140/403 (34%), Gaps = 72/403 (17%) Query: 1378 PTPLANPPVPGSFPNNSGLNPQNSTVSVAA----------VGGVVEDNKESLNVPQDSDC 1427 P L+ P PG+ SG+ P + V A V + ++ Q + Sbjct: 122 PMSLSGQPPPGT----SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL 177 Query: 1428 QNSQSRKEQVNIELK-AVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMRE 1486 Q Q +++Q + + + Q+ + VV + Q + Q + + +N+ + ++ Sbjct: 178 QQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQ 237 Query: 1487 APTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNS 1546 L + L+ PP+ P +Q +P S Sbjct: 238 LQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ----------PPMQQ----PQPPPS 283 Query: 1547 LNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPI 1606 LP +L ++ PP +P + + + LPP T P+ Sbjct: 284 QALPQ-----------QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQT-----QPL 327 Query: 1607 TTSANTSAALPTHLQSALMST----VVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFIN 1662 + A + Q L VV P + V + Q+A Q+ Q + P Sbjct: 328 VSQAQALPGQMLYTQPPLKFVRAPMVVQQPPV--QPQVQQQQTAVQTAQAAQMVAPGVQV 385 Query: 1663 SSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQ--------NIKFSSAPVP 1714 S S + ++ S PS P + T + PP P PQ N SS P P Sbjct: 386 SQSSLPML--SSPS--PGQQVQTPQSMPPP------PQPSPQPGQPSSQPNSNVSSGPAP 435 Query: 1715 -PNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPS 1756 P++ SP+P Q + V + +PSP ++PV PS Sbjct: 436 SPSSFLPSPSP--QPSQSPVTARTPQNFSVPSPGPLNTPVNPS 476 >gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] Length = 1336 Score = 100 bits (250), Expect = 1e-20 Identities = 150/573 (26%), Positives = 206/573 (35%), Gaps = 92/573 (16%) Query: 267 QQQQQQQQQQQQQQQQQQQLQARPP-----QQHQQQQPQGIRPQFTAPTQVPVPPGWNQL 321 +Q + +Q+Q + + +++ P + Q+ Q PQ P P+P + Q Sbjct: 448 EQLKLAMEQEQMGKDESNEIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQA 507 Query: 322 PSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQ 381 P PA + N + L + Q + +AT+Q ++P + Sbjct: 508 WMQNKVPIPAPNEV----LNDRKEDIKLEEKKKTQAEIEQEMATLQY-TNPQLLEQLKIE 562 Query: 382 QASQAHTNF--PQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGS 439 + +Q P S+ PQ QG S++P QQPH + + P + Sbjct: 563 RLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMN--------- 613 Query: 440 PASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQ--QQPP 497 QMGP PQ P G Q + G P+ Q G P FM Q Q PP Sbjct: 614 ----------MAQMGPPGPQGQFRPPGPQGQMGPQGP-PLHQGGGGPQGFMGPQGPQGPP 662 Query: 498 N--------QGPQSL--HPGLGG-MPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGA 546 GPQ + HPG G + + PPG M Q P G G Sbjct: 663 QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGP 722 Query: 547 PQLQANQNVQHAGGQGAGPPQNQ-MQVSHGPPNMM-QPSLMGIHGNMNNQQAGTSG-VPQ 603 P Q H G QG PP Q MQ GP M P GI G +Q G G V Q Sbjct: 723 PGPQG-----HLGPQG--PPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQ--GIQGPVSQ 773 Query: 604 VNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMV 663 L + + QGPP P + Q QG MI+ PQ Sbjct: 774 GPLMGLNPRGMQGPPG----------PRENQGPAPQG-------MIMGHP---PQEMRGP 813 Query: 664 NPPSQNLGPSPQRMTPPKQMLSQQGP----QMMAPHNQMMGPQGQVLLQQNPMIEQIMTN 719 +PP LG PQ M P+++ QGP M+ P ++ GP G QQ P + Sbjct: 814 HPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGS-QSQQGPPQGSLGPP 872 Query: 720 QMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQ 779 G + Q Q N GP +GP P Q G Q+G P Sbjct: 873 PQGGMQGPPGPQGQQNPARGP-HPSQGPIP-FQQQKTPLLGDGPRAPFNQEGQSTGPPPL 930 Query: 780 VMGI-----QGQV--LRP-PGPSPHMAQQHGDP 804 + G+ QG++ L P GP P+ G P Sbjct: 931 IPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPP 963 Score = 86.3 bits (212), Expect = 3e-16 Identities = 163/593 (27%), Positives = 218/593 (36%), Gaps = 124/593 (20%) Query: 249 NRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQ--------QQPQ 300 N+ PA L +++ + +++++ Q + +Q+ LQ PQ +Q +Q + Sbjct: 511 NKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQVE 570 Query: 301 GIRPQFTAPTQVPVP---PG---WNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQ 354 I+P ++ T + P PG +Q+P G QP P+Q M N GP Sbjct: 571 QIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQ----QMPMNMAQM-----GPPG 621 Query: 355 QQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRV 414 Q Q RP Q PP + G P F PQ QG P + Sbjct: 622 PQGQFRPPGPQGQMGPQGPPLHQGG--------------GGPQGFMGPQ--GPQGPPQGL 665 Query: 415 PTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSP 474 P P Q H P Q+ P Q GP PQ + PQG P P Sbjct: 666 PRP-QDMH--------GPQGMQRHPGPHGPLGPQ-----GPPGPQGSSGPQGHMGPQGPP 711 Query: 475 GRNPMVQQGNVPPNFMVMQQQPP----NQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQ 530 G QG++ P Q PP + GPQ PG GM P G +P+ +Q Sbjct: 712 G-----PQGHIGP------QGPPGPQGHLGPQG-PPGTQGMQGPPGPRGMQGPPHPHGIQ 759 Query: 531 GQVPSTTATTPGNSGAPQLQANQNVQHAGG--QGAGPPQNQMQVSHGPPNMMQPSLM-GI 587 G S P + G + +Q G + GP M + H P M P G+ Sbjct: 760 GGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGL 819 Query: 588 HGNMNNQQAGTSGVPQVNLSNMQGQPQQ----GPPSQLMGMHQQIVPSQGQMVQQQGTLN 643 G+ + G PQ + MQG P Q GPP +L G SQ Q QG+L Sbjct: 820 LGHGPQEMRG----PQ-EIRGMQGPPPQGSMLGPPQELRGP----PGSQSQQGPPQGSLG 870 Query: 644 PQNPMILSRAQLMPQGQMMVNP-----PSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQM 698 P P + PQGQ NP PSQ P Q+ TP L GP+ AP NQ Sbjct: 871 PP-PQGGMQGPPGPQGQQ--NPARGPHPSQGPIPFQQQKTP----LLGDGPR--APFNQ- 920 Query: 699 MGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPN---MQGNM 755 +GQ P+I + QG N PG +GP PN +G Sbjct: 921 ---EGQ-STGPPPLIPGLGQQGAQGRIPPLN--------PG-----QGPGPNKGDSRGPP 963 Query: 756 VQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPP----GPSPHMAQQHGDP 804 G MS + Q G + P + GQ R P GP P P Sbjct: 964 NHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRP 1016 Score = 57.4 bits (137), Expect = 1e-07 Identities = 103/384 (26%), Positives = 126/384 (32%), Gaps = 79/384 (20%) Query: 909 TNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSN 968 TN ++ K R + + + P + +G P PG+ GP S Sbjct: 551 TNPQLLEQLKIERLAQKQVEQIQPPPS--SGTPLLGPQPFPGQ--------GP----MSQ 596 Query: 969 RPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ----PQSQ 1024 P G+ QP P QQMP + Q P PQ + P PQ Q PP Q PQ Sbjct: 597 IPQGF-QQP---HPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGF 652 Query: 1025 QQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP-PRGPLNPDSQRMPMQQSGSVPVMVSLQ 1083 Q Q L QD + P HP P GPL P P SG M Sbjct: 653 MGPQGPQGPPQGLPRPQD---MHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHM---- 705 Query: 1084 GPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSV 1143 GP PP P P P G PQ P + M P G + P Sbjct: 706 GPQG-PPGPQGHIGPQGPPGPQG--------HLGPQGPPGT--QGMQGPPGPRGMQGPPH 754 Query: 1144 P----GGPNNMPSHVVLPQNQLM------MTGP-----KPGPSPLSATQGATPQQ----- 1183 P GGP + + Q LM M GP GP+P G PQ+ Sbjct: 755 PHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPH 814 Query: 1184 PPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTE---PSEISLS 1240 PP L GH + P + + P PQ P S P + SL Sbjct: 815 PPGGLL----GHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLG 870 Query: 1241 PERLNASIAGLFPPQINIPLPPRP 1264 P PPQ + PP P Sbjct: 871 P-----------PPQGGMQGPPGP 883 Score = 55.8 bits (133), Expect = 4e-07 Identities = 79/336 (23%), Positives = 103/336 (30%), Gaps = 36/336 (10%) Query: 925 NSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQ 984 + Q +N P G + +PP G QG + GP L + P G+ Q P Q Sbjct: 607 SQQMPMNMAQMGPPGPQGQFRPP--GPQG-QMGPQGPPLHQGGGGPQGFMGPQGPQGPPQ 663 Query: 985 QMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ----PQSQQQQQQQQQMMMMLMMQ 1040 +P H PQ Q+ P P P Q PP Q PQ Q + Q Sbjct: 664 GLPRPQDMH---GPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQ 720 Query: 1041 QDPKSVRL------PVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASV------ 1088 P P +Q + P GP P G P +QGP S Sbjct: 721 GPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGG-PGSQGIQGPVSQGPLMGL 779 Query: 1089 -------PPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAP 1141 PP P + + P P +G ++M P EM E G + P Sbjct: 780 NPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGP 839 Query: 1142 SVPGGPNNMPSHVVLPQNQLMMTGPKP---GPSPLSATQGATPQQPPVNSLPSSHGHHFP 1198 G P + P GP GP P QG Q N H P Sbjct: 840 PPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGP 899 Query: 1199 NVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEP 1234 P Q + P+ + + PP P Sbjct: 900 ---IPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIP 932 Score = 36.2 bits (82), Expect = 0.34 Identities = 69/245 (28%), Positives = 82/245 (33%), Gaps = 61/245 (24%) Query: 170 GPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQ 229 G G M P + G SM+ GP EL R P P SQS QQ Sbjct: 821 GHGPQEMRGPQEIRGMQGPPPQGSML--GPPQEL--RGP-PGSQS-------------QQ 862 Query: 230 SHPSGSLA-PPHHPMQ-PVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQ 287 P GSL PP MQ P Q NPA P Q QQQ+ L Sbjct: 863 GPPQGSLGPPPQGGMQGPPGPQGQQNPARGP------------HPSQGPIPFQQQKTPLL 910 Query: 288 ARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPP--PAQGSLGTMTANQGWK 345 P+ Q+ Q P P+ PG Q + PP P QG N+G Sbjct: 911 GDGPRAPFNQEGQSTGPP-------PLIPGLGQQGAQGRIPPLNPGQGP----GPNKGDS 959 Query: 346 KAP---LPGPMQQQLQARPSLATVQTPSHPPPPYPF-------GSQQASQAHTNFP-QMS 394 + P GPM ++ + P H P PF G H +FP S Sbjct: 960 RGPPNHHMGPMSERRHEQSG-----GPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFS 1014 Query: 395 NPGQF 399 P F Sbjct: 1015 RPDDF 1019 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 97.4 bits (241), Expect = 1e-19 Identities = 229/1006 (22%), Positives = 341/1006 (33%), Gaps = 176/1006 (17%) Query: 924 KNSQQDL---NTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQ 980 ++SQQ + + D P+ + PP+ +G L S P L + +P P PV Sbjct: 629 QSSQQSVMLGSLADAAPSPAQCVCSPPV--SEGPVLPQSLPSLGAYQ-QPTAAPGLPVGS 685 Query: 981 RPLQQMPPQLMQHVAPPPQ------PPQQQPQPQLPQQ-----QQPPPPSQPQSQQQQQQ 1029 P PP L QH P PP P P P Q QQPPP +QP Q Sbjct: 686 VPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLA 745 Query: 1030 QQQMMMMLMMQQDPKSVRLPVSQNVHP--------PRGPLNPDSQRMP-MQQSGSVPVMV 1080 Q ++ + + P SQ P P+ PL P +Q P M VP + Sbjct: 746 PQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPIT 805 Query: 1081 SLQGPASVPPS-PDKQRMPMPVNTPLGSNSRKMVYQESPQNPS-SSPLAEMASLPEASGS 1138 L G +PP+ PD +P P S ++ PS ++PL + Sbjct: 806 PLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL------PSLAAPLPPASPALPLQAV 859 Query: 1139 EAPSVPGGPNNMPSHVVLPQN----QLMMTGPKPGPSPLS------------ATQGATPQ 1182 + P PG P MP ++P L+ P PG + LS A PQ Sbjct: 860 KLPHPPGAPLAMPCRTIVPNAPATIPLLAVAP-PGVAALSIHSAVAQLPGQPVYPAAFPQ 918 Query: 1183 QPPVNSLPSSHGHHFPNV-AAPTQTSRPKTPNR-----ASPRPYYPQTPNNRPPSTEPSE 1236 P + PS H H N+ A P Q + P P P+P P P P T P + Sbjct: 919 MAPTDVPPSPH-HTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQ 977 Query: 1237 ISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSN 1296 L P+ + + PPQ +P+ P P Q L A L +P+ Sbjct: 978 PVLPPQPM-LPPQPVLPPQPALPVRPEPL------QPHLPEQAAPAATPGSQILLGHPAP 1030 Query: 1297 FATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTL 1356 +A ++ +V V + + P+ S T S Q+ TL Sbjct: 1031 YAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATL 1090 Query: 1357 ASQTNAALLQNVELPRNVLVSPTPLAN----------------PPVPGSFPNNSGLN--- 1397 N L + SP P P +P S + G + Sbjct: 1091 LPPANPPLPGGPG-----IASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTS 1145 Query: 1398 --PQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPE 1455 + + A GG +E + + + ++ Q R + + + V KMV + Sbjct: 1146 GKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQ 1205 Query: 1456 DQS--------KKDGQPSDPNKLPSVEENKNLVSPAMRE------------APTSLSQLL 1495 ++ K D P+++ + + + A RE A LS+ Sbjct: 1206 LETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDT 1265 Query: 1496 DNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNE- 1554 D + PP L+ T + +GE+ ++ S + P N+ H+ + Sbjct: 1266 DADRGSDPGTSPPHLS----TCGLGTGEESRQ----------SQANAPVYQQNVLHTGKR 1311 Query: 1555 ---LCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTP----LPPNQITVFVTSNPIT 1607 +C HP S +P + P+ S P +S S P L + F+ S + Sbjct: 1312 WFIICPVAEHPAPEAPES--SPPL-PLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLL 1368 Query: 1608 TSA---NTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNA-------RPQFIT 1657 + A N A P L + V +P G+ S A A PQ +T Sbjct: 1369 SQAGPSNPPGAPPAPLAPS-SPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLT 1427 Query: 1658 PVFINSSSIIQVMKGS---QPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVP 1714 S + + + QP + AP T P A P+ P+P Sbjct: 1428 SELETSQPLAETHEAPLAVQPLVVGLAPCTP-----APEAASTRDASAPRE------PLP 1476 Query: 1715 PNALSSSP---APNIQTGRPLVLSSRATPV------QLPSPPCTSSPVVPSHPPVQQVKE 1765 P A SP P G+P L A QLPSPP P VP PP Sbjct: 1477 PPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPL--GPTVPPQPP----SA 1530 Query: 1766 LNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPV 1811 L D P +T+ S + P SS + +PV Sbjct: 1531 LESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPV 1576 Score = 50.4 bits (119), Expect = 2e-05 Identities = 105/440 (23%), Positives = 145/440 (32%), Gaps = 86/440 (19%) Query: 288 ARPP--QQHQQQQPQGIRPQFTAPTQVPVPPGWNQ-LPSGALQPPPAQGSLGTMTANQGW 344 A PP QQH P P+ P+P G Q P G PP AQ Sbjct: 690 ACPPSLQQHFPDPAMSFAPVLPPPS-TPMPTGPGQPAPPGQQPPPLAQ------------ 736 Query: 345 KKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQM 404 P P+ Q L +P + P H PP SQ + A QM AP Sbjct: 737 -----PTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQ-----APLQ 786 Query: 405 KSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQ---------QQMGP 455 Q P P P+ P P + A+ P V Q P Sbjct: 787 PLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAP 846 Query: 456 RPPQNNPLPQGFQQPVSSPGRNPMVQQ-----GNVPPNFMVMQQQPPNQGPQSLHPGLGG 510 PP + LP + PG P+ N P ++ PP S+H + Sbjct: 847 LPPASPALPLQAVKLPHPPGA-PLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQ 905 Query: 511 MPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQM 570 +P + P + A A P VP + T QN++ Q A PPQ + Sbjct: 906 LPGQ--PVYPA--AFPQMAPTDVPPSPHHTV-----------QNMRATPPQPALPPQPTL 950 Query: 571 QVSHGPPNMM---QPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGP-PSQLMGMHQ 626 PP + QP+L PQ L +P Q P Q M Q Sbjct: 951 -----PPQPVLPPQPTL----------------PPQPVLPPQPTRPPQPVLPPQPMLPPQ 989 Query: 627 QIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPS----QNLGPSPQRMTPPKQ 682 ++P Q + + L P P + A P Q+++ P+ P PP Sbjct: 990 PVLPPQPALPVRPEPLQPHLPEQAAPA-ATPGSQILLGHPAPYAVDVAAQVPTVPVPPAA 1048 Query: 683 MLSQQGPQMMAPHNQMMGPQ 702 +LS P+++ P + PQ Sbjct: 1049 VLSPPLPEVLLPAAPELLPQ 1068 Score = 48.1 bits (113), Expect = 9e-05 Identities = 148/674 (21%), Positives = 221/674 (32%), Gaps = 124/674 (18%) Query: 920 PRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVE 979 P + QQD+ +PD +A PP+P + + Y +Q + Sbjct: 548 PALQPKEQQDVGSPD-------KARGPPVPLQVQVT-----------------YHAQAGQ 583 Query: 980 QRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMM 1039 P + P+ QH+ PP P Q QQ +M+ + Sbjct: 584 PGPPEPEEPEADQHLLPPTLPTSATSLAS--DSTFDSGQGSTVYSDSQSSQQSVMLGSLA 641 Query: 1040 QQDPKSVRLPVSQNVHPPRGPLNPDS--QRMPMQQSGSVPVMVSLQGPA-SVPPS----- 1091 P + S V GP+ P S QQ + P + PA + PPS Sbjct: 642 DAAPSPAQCVCSPPV--SEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHF 699 Query: 1092 PDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMP 1151 PD PV P + Q +P PLA+ LP+ + P VP P +P Sbjct: 700 PDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQ-PVVPLQP--VP 756 Query: 1152 SHV---VLPQNQL---MMTGPKPGP-SPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPT 1204 H+ + P +Q+ P P +PL PQ PP+ +P Sbjct: 757 PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVP-------------- 802 Query: 1205 QTSRPKTPNRA--SPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPP-------- 1254 P TP P P P P P + SP + S+A PP Sbjct: 803 ----PITPLAGIDGLPPALPDLPTATVPPVPPPQY-FSPAVILPSLAAPLPPASPALPLQ 857 Query: 1255 QINIPLPPRPNLNRGFDQQGLN-PTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSG 1313 + +P PP L N P T+ + AP + + A Q G Sbjct: 858 AVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQL---------PG 908 Query: 1314 KQSNSGATKRASPSN---SRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVEL 1370 + A + +P++ S + + R T P P + P+ TL Q L L Sbjct: 909 QPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQP----ALPPQPTLPPQ--PVLPPQPTL 962 Query: 1371 PRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNS 1430 P ++ P P PP P P L PQ V + E L + Sbjct: 963 PPQPVLPPQP-TRPPQP-VLPPQPMLPPQ----PVLPPQPALPVRPEPLQPHLPEQAAPA 1016 Query: 1431 QSRKEQVNIELKAVPAQEVKMVVP----------EDQSKKDGQPSDPNKLPSVEENKNLV 1480 + Q+ + A A +V VP + P+ P LP + V Sbjct: 1017 ATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATV 1076 Query: 1481 SPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSS 1540 S +++ PT + LL PP L P + S + +V P ++ +S Sbjct: 1077 SASVQSVPTQTATLL-----------PPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQ 1125 Query: 1541 KEPSNSLNLPHSNE 1554 +P LP S E Sbjct: 1126 DKPP---GLPQSCE 1136 Score = 47.4 bits (111), Expect = 1e-04 Identities = 74/282 (26%), Positives = 101/282 (35%), Gaps = 48/282 (17%) Query: 232 PSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPP 291 P G A H + + PA FPQ+ Q + Q A PP Sbjct: 891 PPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQP----ALPP 946 Query: 292 QQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPG 351 Q QP + PQ T P Q +PP + P L P P Sbjct: 947 QPTLPPQPV-LPPQPTLPPQPVLPPQPTRPPQPVLPPQPML------------------- 986 Query: 352 PMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQ--MSNPGQFT---APQMKS 406 P Q L +P+L P P P P +QA+ A T Q + +P + A Q+ + Sbjct: 987 PPQPVLPPQPAL-----PVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPT 1041 Query: 407 LQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPR-----PPQNN 461 + P+ V +P L +P P P+S TV+ + Q + + PP N Sbjct: 1042 VPVPPAAVLSPPLPEVLLPAAPELLPQF-----PSSLATVSASVQSVPTQTATLLPPANP 1096 Query: 462 PLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQS 503 PLP G ++SP P VQ P Q P PQS Sbjct: 1097 PLPGG--PGIASP--CPTVQLTVEPVQEEQASQDKPPGLPQS 1134 Score = 42.4 bits (98), Expect = 0.005 Identities = 78/303 (25%), Positives = 102/303 (33%), Gaps = 48/303 (15%) Query: 992 QHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVS 1051 + + P QP +QQ + + PP P Q Q Q Q P+ Sbjct: 544 ERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQ--------PGPPEPEEPEAD 595 Query: 1052 QNVHPPRGPLNPDSQRMP-----------MQQSGSVPVMVSLQGPASVPPSPDKQRMPMP 1100 Q++ PP P + S S S V L A PSP + P Sbjct: 596 QHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPP 655 Query: 1101 VNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEAS-GSEAPSVPGG--PNNMPSHVVLP 1157 V+ E P P S P P A+ G SVP P ++ H P Sbjct: 656 VS-------------EGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDP 702 Query: 1158 QNQLMMTGPKPG-PSPLSATQGATP-QQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRA 1215 P P P P Q A P QQPP + P+ P V AP Q P P Sbjct: 703 AMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTP----LPQVLAP-QPVVPLQPVPP 757 Query: 1216 SPRPYY-PQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQG 1274 PY P + P +P ++ +P + A + PP IP+ P G D G Sbjct: 758 HLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPP---IPVVPPITPLAGID--G 812 Query: 1275 LNP 1277 L P Sbjct: 813 LPP 815 Score = 40.0 bits (92), Expect = 0.024 Identities = 80/346 (23%), Positives = 132/346 (38%), Gaps = 44/346 (12%) Query: 1702 IPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQ 1761 +P SAP + LSS P+ + L+ S+A P P P +P+ PS PPV Sbjct: 1338 LPPEASQDSAPYK-DQLSSKEQPSFLASQQLL--SQAGPSNPPGAP--PAPLAPSSPPVT 1392 Query: 1762 QVKELNPDEASPQVNTSADQNTLPSSQS------TTMVSPLLTNSPGSSGNRRSPVSSSK 1815 + + D A+P +T + + +SQ+ + S L T+ P + +P++ Sbjct: 1393 ALPQ---DGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAE-THEAPLAVQP 1448 Query: 1816 ---GKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLST 1872 G + T+ L + T L AP L + Sbjct: 1449 LVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVS 1508 Query: 1873 ELDSKTPTPPAPTLLKMTSSPVGPGTASA---GPSLPGGALPTSVRSIVTTLVPSELISA 1929 S+ P+PP L T P P + GP G + ++++S+ L Sbjct: 1509 LATSQLPSPP----LGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEH 1564 Query: 1930 VPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTALQASVARPEL 1989 VPT+ ++ AG VE VG L + Q + +A P + Sbjct: 1565 VPTSSAS---------AGTPVE--VGDRDFTLEPLRGDQ------PRSEVCGGDLALPPV 1607 Query: 1990 EVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHR 2035 A VSG+ P+ +VEKS++ R + E+ T +S + E+ R Sbjct: 1608 PKEA--VSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPR 1651 Score = 36.6 bits (83), Expect = 0.26 Identities = 109/487 (22%), Positives = 160/487 (32%), Gaps = 86/487 (17%) Query: 408 QGGPSRVPTPLQQPHL------TNKSPASSPSSFQQGSPASSPTVNQTQQQM-------- 453 Q GP P HL T+ + +S S+F G ++ + +Q+ QQ Sbjct: 583 QPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLAD 642 Query: 454 ----------------GPRPPQNNPLPQGFQQPVSSPGR----------NPMVQQGNVPP 487 GP PQ+ P +QQP ++PG P +QQ P Sbjct: 643 AAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDP 702 Query: 488 NFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAP 547 PP P PG P + PP + P + Q P + Sbjct: 703 AMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPY 762 Query: 548 QLQANQNVQHAGGQGAGPPQNQMQ-VSHGPPNMMQ-PSLMGIHGNMNNQQAGTSGVPQVN 605 A+Q A + PQ +Q ++ PP M P + I AG G+P Sbjct: 763 LAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPI-----TPLAGIDGLPPAL 817 Query: 606 LSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNP 665 PP Q I+PS L P +P + +A +P +P Sbjct: 818 PDLPTATVPPVPPPQYFS-PAVILPSLA------APLPPASPALPLQAVKLP------HP 864 Query: 666 PSQNLGPSPQRMTP------PKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTN 719 P L + + P P ++ G ++ H+ + GQ + P M Sbjct: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVY---PAAFPQMAP 921 Query: 720 QMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQ--QGPVNNSP 777 QN P PA + P Q T + PQ + P P Sbjct: 922 TDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLP 981 Query: 778 SQVMGIQGQVLRPPGPS---------PHMAQQHGDPATTANNDVSLSQMMP---DVSIQ- 824 Q M + Q + PP P+ PH+ +Q PA T + + L P DV+ Q Sbjct: 982 PQPM-LPPQPVLPPQPALPVRPEPLQPHLPEQ-AAPAATPGSQILLGHPAPYAVDVAAQV 1039 Query: 825 QTNMVPP 831 T VPP Sbjct: 1040 PTVPVPP 1046 Score = 34.7 bits (78), Expect = 0.99 Identities = 52/216 (24%), Positives = 70/216 (32%), Gaps = 19/216 (8%) Query: 374 PPYPFGSQQASQAHTNFP---QMSNPGQ--FTAPQMKSLQGGPSRVPTPLQQPHLTNKSP 428 PP P S + + P Q+S+ Q F A Q Q GPS P P L SP Sbjct: 1331 PPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAP-LAPSSP 1389 Query: 429 ASSPSSFQQGSPASS----PTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGN 484 + +PA+S P Q GP PQ QP++ P+ Q Sbjct: 1390 PVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQP- 1448 Query: 485 VPPNFMVMQQQPPNQGPQSLHPGLGGMPKR-LPPGFSAGQANPNFMQGQVPSTTATTPGN 543 +V+ P P++ P+ LPP + Q + P Sbjct: 1449 -----LVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAA 1503 Query: 544 SGAPQLQANQNVQHAGGQGA--GPPQNQMQVSHGPP 577 GA L +Q G PP GPP Sbjct: 1504 VGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP 1539 Score = 33.9 bits (76), Expect = 1.7 Identities = 97/444 (21%), Positives = 156/444 (35%), Gaps = 61/444 (13%) Query: 947 PLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQ 1006 P P E D S P+ P P P Q L Q P L V Q P Sbjct: 1458 PAP-EAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPS 1516 Query: 1007 PQLPQQQQPPPPSQPQSQQQ-------------QQQQQQMMMMLMMQQDPKSVRLPVSQN 1053 P L P PPS +S + + +++ +L + P S S + Sbjct: 1517 PPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTS-----SAS 1571 Query: 1054 VHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMV 1113 P + D P++ G P G ++PP P K+ + V P + + Sbjct: 1572 AGTPVEVGDRDFTLEPLR--GDQPRSEVCGGDLALPPVP-KEAVSGRVQLP------QPL 1622 Query: 1114 YQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNN------MPSHVV--LPQNQLMMTG 1165 ++S P+ + E + + +P G + SHVV +PQ+ Sbjct: 1623 VEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVR 1682 Query: 1166 P-KPGPSPLSATQ-GATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNR---ASPRPY 1220 P + P+ + G + +PP + + + G Q S P+T SPR Sbjct: 1683 PARVEPTDRDGGEAGESSAEPPPSDMGTVGG----------QASHPQTLGARALGSPRKR 1732 Query: 1221 YPQTPNNRPPST--EPSEISLSPERLNASIAGL---FPPQINI-PLPPRPNLNRGFDQQG 1274 Q + P T S +S E AS L PP + + P P++ + Sbjct: 1733 PEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQ 1792 Query: 1275 LNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSP 1334 + +G+ S+ + + A P K S+ V+ + K+A+ R S Sbjct: 1793 TASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGD--FVKKATAFLQRPSRA 1850 Query: 1335 GSSRKTTPSPGRQNSKAPKLTLAS 1358 GS TPS R K P +++ S Sbjct: 1851 GSLGPETPS--RVGMKVPTISVTS 1872 Score = 33.1 bits (74), Expect = 2.9 Identities = 43/191 (22%), Positives = 70/191 (36%), Gaps = 30/191 (15%) Query: 1658 PVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNA 1717 P F+ S ++ S P P APL +S PP A+ P S+ P P + Sbjct: 1359 PSFLASQQLLSQAGPSNPPGAPPAPLAPSS---PPVTALPQDGAAPAT---STMPEPASG 1412 Query: 1718 LSSSP---------APNIQTGRPLVLSSRA----TPVQLPSPPCTSSP--------VVPS 1756 +S ++T +PL + A P+ + PCT +P P Sbjct: 1413 TASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPR 1472 Query: 1757 HPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSP--GSSGNRRSPVS-S 1813 P E +P +PQ LP++ ++ SP G + + P + Sbjct: 1473 EPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALE 1532 Query: 1814 SKGKGKVDKIG 1824 S G+G ++G Sbjct: 1533 SDGEGPPPRVG 1543 >gi|56549696 E1A binding protein p400 [Homo sapiens] Length = 3122 Score = 96.7 bits (239), Expect = 2e-19 Identities = 157/595 (26%), Positives = 224/595 (37%), Gaps = 112/595 (18%) Query: 152 PMGA--GNS-VRMEAGFPMASGPGII-RMNNPAT--VMIPPGGNVSSSMMAPGPNPEL-- 203 P GA GN V AG P A+ I R+ +P + PGG+ + ++ P P Sbjct: 2589 PTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVG 2648 Query: 204 QPRTPRPASQSDAMDPLLSGL-----------HIQQQSHPSGSLAPPHHPMQPVSV-NRQ 251 P T P S A + + ++ P+ SL P V + + Sbjct: 2649 SPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKT 2708 Query: 252 MNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQ 311 + PA+F L+QQQQQQQQQQQQQQQQQQQQQQQQ QQQQ Q T +Q Sbjct: 2709 ITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQ---------QQQQ------QTTTTSQ 2753 Query: 312 VPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSH 371 V VP G Q P ++G +T L +Q+LQ P Q S Sbjct: 2754 VQVPQ-----IQGQAQSPAQIKAVGKLTPEH------LIKMQKQKLQMPPQPPPPQAQSA 2802 Query: 372 PPPPYPFGSQQASQAHTNFPQMSNP--GQFTAPQMKSLQGGP----------SRVPTPLQ 419 PP P Q SQ PQ +P TAP+ +L G +RVPT Sbjct: 2803 PPQPTAQVQVQTSQP----PQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQL 2858 Query: 420 QPHLTNKSPASSPSSFQQGSP--ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRN 477 Q ++ A P+ P S P + + P + QP + G+ Sbjct: 2859 QAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQT 2918 Query: 478 PMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTT 537 + Q ++ + QQ Q K + P + G P +Q ++ + Sbjct: 2919 VVAQPVHMQQLLKLKQQAVQQQ-------------KAIQPQAAQG---PAAVQQKITAQQ 2962 Query: 538 ATTPGNSGAPQLQANQNVQHAG-----GQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMN 592 TTPG A Q V +A Q P +Q Q G + + + Sbjct: 2963 ITTPG--------AQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVV 3014 Query: 593 NQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQI-----VPSQGQMVQQQGTLNPQNP 647 QQ + + QV ++ Q PQ +Q QQ+ V + Q+VQQ+ L Q Sbjct: 3015 QQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQK--LIQQQV 3072 Query: 648 MILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGP-QMMAPHNQMMGP 701 + + A L G P+P ++ SQQ QM P ++ P Sbjct: 3073 VTTASAPLQTPG-----------APNPAQVPASSDSPSQQPKLQMRVPAVRLKTP 3116 Score = 62.0 bits (149), Expect = 6e-09 Identities = 151/700 (21%), Positives = 248/700 (35%), Gaps = 112/700 (16%) Query: 951 EQGINLDNSGPKLPEFSNRPPGYPS--------QPVEQRPLQQMPPQLMQHVAPPPQPPQ 1002 E GIN D P + S R Q +Q + Q PP Q PP QPP Sbjct: 2463 ESGINYDKPLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPP 2522 Query: 1003 QQPQPQLPQQQQP--PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGP 1060 PQPQ Q P PP QPQ Q Q Q Q Q + Q ++ S V Sbjct: 2523 PLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQ--PAITTGGSAAVLAGTIK 2580 Query: 1061 LNPDSQRMPM-QQSGSVPVMVSLQGPASVPPSPDKQRMPMPV-----NTPLGSNSRKMVY 1114 + MP SG+V V PA+ S +K R+ PV TP GS ++V+ Sbjct: 2581 TSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINK-RLASPVAPGALTTPGGSAPAQVVH 2639 Query: 1115 QESPQNPSSSPLA---EMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPS 1171 + P SP ++ S+ G A + ++ + V+ N + P Sbjct: 2640 TQPPPRAVGSPATATPDLVSMATTQGVRAVT------SVTASAVVTTNLTPVQTPARSLV 2693 Query: 1172 PLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPS 1231 P +Q Q P P+ HF + Q + + + + Q + + Sbjct: 2694 P-QVSQATGVQLPGKTITPA----HFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQT 2748 Query: 1232 TEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLT 1291 T S++ + PQI Q +P +KA+G+ Sbjct: 2749 TTTSQVQV--------------PQI--------------QGQAQSPAQIKAVGK------ 2774 Query: 1292 MNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRK------TTPSPG 1345 + P + Q KL Q+ S + + + S P + T P PG Sbjct: 2775 LTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPG 2834 Query: 1346 R-------QNSKAPKLTL--ASQTNAALLQNVELPRNVLVSPTPLANPP---VPGSFPNN 1393 N + +LT SQ A + P+ V+ LA PP VP + ++ Sbjct: 2835 ALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVA---LAKPPVVSVPAAVVSS 2891 Query: 1394 SGLN--PQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKM 1451 G+ P N A+G + +++ V Q Q K+Q + KA+ Q + Sbjct: 2892 PGVTTLPMNVAGISVAIGQPQKAAGQTV-VAQPVHMQQLLKLKQQAVQQQKAIQPQAAQG 2950 Query: 1452 VVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMRE--APTSLSQLLDNSGAPNVTIKPPG 1509 Q Q + P V PA++ T +SQ +GA V Sbjct: 2951 PAAVQQKITAQQITTPGAQQKV---AYAAQPALKTQFLTTPISQAQKLAGAQQVQ----- 3002 Query: 1510 LTDLEVT--PPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSS---LVHPEL 1564 T ++V P VV ++ + + ++Q ++S+ + ++ + + + + P + Sbjct: 3003 -TQIQVAKLPQVV-----QQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAV 3056 Query: 1565 SEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSN 1604 + + V + +S+ + TP PN V +S+ Sbjct: 3057 TATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASSD 3096 Score = 54.3 bits (129), Expect = 1e-06 Identities = 148/700 (21%), Positives = 237/700 (33%), Gaps = 107/700 (15%) Query: 199 PNPELQPRTPRP-------ASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHP---MQP--- 245 P E + + RP A +A L H +G +PP P M P Sbjct: 2394 PREEGKSKNNRPLRTSQIYAQDENATHTQLYTSHFDLMKMTAGKRSPPIKPLLGMNPFQK 2453 Query: 246 ------------VSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQ---QQQQLQARP 290 ++ ++ + P L+ ++ ++++ QQ+ QQ Q Q +P Sbjct: 2454 NPKHASVLAESGINYDKPLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQP 2513 Query: 291 PQQHQQQQPQGIRPQFTAPTQVPVPPGWNQ---LPSGALQPPPAQGSLGTMTA-NQGWKK 346 P QQ P +PQ A +Q P P Q P QP P Q A G Sbjct: 2514 PPPPQQPPPPLPQPQ-AAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSA 2572 Query: 347 APLPGPMQQQL--QARPSLA----TVQTPSHPPPPYPFGSQQASQAHTNFP-QMSNPGQF 399 A L G ++ + + P+ A + P F S A P ++ PG Sbjct: 2573 AVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGS 2632 Query: 400 TAPQMKSLQGGPSRVPTP-LQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPP 458 Q+ Q P V +P P L + + + + ++ T N T Q P Sbjct: 2633 APAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQ----TP 2688 Query: 459 QNNPLPQGFQQP-VSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPP 517 + +PQ Q V PG+ P +F +++QQ Q Q Sbjct: 2689 ARSLVPQVSQATGVQLPGKT------ITPAHFQLLRQQQQQQQQQQQ------------- 2729 Query: 518 GFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPP 577 Q Q Q TT PQ+Q GQ P Q + P Sbjct: 2730 --QQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQ---------GQAQSPAQIKAVGKLTPE 2778 Query: 578 NMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQ 637 ++++ + P + +Q Q Q P Q + P G ++ Sbjct: 2779 HLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLT 2838 Query: 638 QQGTLNPQNPMI--LSRAQLMPQGQMMVN--PPSQNLGPSPQRMTPPKQMLSQQG----P 689 N Q + + +QL QGQM P+Q P ++ P ++S G P Sbjct: 2839 GTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLP 2898 Query: 690 QMMAPHNQMMG-PQ---GQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMR 745 +A + +G PQ GQ ++ Q ++Q++ + Q +QQ Q Q+ GPA + + Sbjct: 2899 MNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQA--AQGPAAVQQ 2956 Query: 746 G------PTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQ 799 TP Q V + Q + + P++ + Q Q P + Q Sbjct: 2957 KITAQQITTPGAQ-QKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQ 3015 Query: 800 QHGDPATTANNDVSLSQMMPDVSI---------QQTNMVP 830 Q P + S SQ ++ QQ M+P Sbjct: 3016 QQ-TPVASIQQVASASQQASPQTVALTQATAAGQQVQMIP 3054 Score = 52.8 bits (125), Expect = 4e-06 Identities = 183/840 (21%), Positives = 255/840 (30%), Gaps = 187/840 (22%) Query: 350 PGPMQQQLQ---ARPSLATVQTPSHP-PPPYPFG--------------SQQASQAHTNFP 391 P +Q QLQ A P + P+HP PPP P S Q Q P Sbjct: 7 PQNVQHQLQRSRACPGSEGEEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQIQQLMNRSP 66 Query: 392 QMSNPGQFTAPQMKSLQGGPSRV---PTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQ 448 T + + GG ++ P PL P ++ P F+ GSP+ + Sbjct: 67 ATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHGSPSYIQVTSP 126 Query: 449 TQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQG-------- 500 QQ+ + P QP PG+ + P + + P G Sbjct: 127 LSQQVQTQSP---------TQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLV 177 Query: 501 -PQSLHPGLGGMPKRLPPGFSAGQANPNFMQG-----QVPSTTATT-PGNSGAPQLQANQ 553 SL P GG F G QG Q P T T P Q+ Sbjct: 178 RQISLSPSSGGHFV-----FQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGG 232 Query: 554 NVQHAGGQ------GAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLS 607 + H G Q GAG +QP H N S + Q L Sbjct: 233 TIHHLGPQSPAAAGGAG---------------LQPLASPSHITTANLPPQISSIIQGQLV 277 Query: 608 NMQGQPQQGPP-SQLMGMHQQ---IVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMV 663 Q Q QGPP + +G + ++P G G +P P SR + P + Sbjct: 278 QQQ-QVLQGPPLPRPLGFERTPGVLLPGAGG-AAGFGMTSPPPPTSPSRTAVPPGLSSLP 335 Query: 664 NPPSQNLGPSP-----QRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMT 718 N G + + P ++Q Q + H Q M +V + +IE Sbjct: 336 LTSVGNTGMKKVPKKLEEIPPASPEMAQMRKQCLDYHYQEMQALKEVFKEY--LIELFFL 393 Query: 719 NQMQGNKQQFNTQNQSNVMPGPA-----------------------------QIMRGPTP 749 QGN F + + P A Q + G Sbjct: 394 QHFQGNMMDFLAFKKKHYAPLQAYLRQNDLDIEEEEEEEEEEEEKSEVINDEQALAGSLV 453 Query: 750 NMQGNMVQFTGQMSGQMLPQQGPVNNS--PSQVMGIQGQVLRPPGPSPHMAQQHGDPATT 807 G+ V+ Q +P G S P +G QG V + PG Sbjct: 454 AGAGSTVETDLFKRQQAMPSTGMAEQSKRPRLEVGHQGVVFQHPG--------------- 498 Query: 808 ANNDVSLSQMMPDVSIQQTNMVP-PHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQM 866 A+ V L Q+MP Q M P P + G S + P +G P N Sbjct: 499 ADAGVPLQQLMPTA---QGGMPPTPQAAQLAGQRQSQQQYD--------PSTGPPVQNAA 547 Query: 867 S----CGQNPGF--PVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPP 920 S Q PG P S L Q + + N P P Sbjct: 548 SLHTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPP- 606 Query: 921 RKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEF--SNRPPGYPSQPV 978 L P ++PA L A P PG+ + LP+ S R P P+ P Sbjct: 607 ------SSQLPIPPSQPAQL--ALHVPTPGKVQVQASQLS-SLPQMVASTRLPVDPAPPC 657 Query: 979 EQRPLQQMPPQLMQHVA---PPPQPPQQQP--QPQLPQQQQPPP------------PSQP 1021 RPL + V+ P P P + P +P + P P++P Sbjct: 658 -PRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKP 716 Query: 1022 QSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNP----DSQRMPMQQSGSVP 1077 QS Q Q QD + ++ + VH L +R+P Q P Sbjct: 717 QSPAQNATSSQ-----DSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPRP 771 Score = 48.9 bits (115), Expect = 5e-05 Identities = 178/826 (21%), Positives = 278/826 (33%), Gaps = 171/826 (20%) Query: 644 PQNPMI-LSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQ 702 PQN L R++ P + P N PSP P S PQ +P Q+ Sbjct: 7 PQNVQHQLQRSRACPGSEGEEQPAHPNPPPSPAAPFAPSA--SPSAPQ--SPSYQI---- 58 Query: 703 GQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQG--------- 753 Q L+ ++P Q + +Q Q + P P P+P G Sbjct: 59 -QQLMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPL-----PSPTSPGFQFSAQPRR 112 Query: 754 ------NMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATT 807 + +Q T +S Q + Q P SP +Q PGP + ++ Sbjct: 113 FEHGSPSYIQVTSPLS-QQVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCS-----SSP 166 Query: 808 ANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHF---SGHGMSFNAPFSGAPNGN 864 V S ++ +S+ + +SG HF G G++ A G Sbjct: 167 TGGFVDASVLVRQISL---------------SPSSGGHFVFQDGSGLTQIA------QGA 205 Query: 865 QMSCGQNPGFPV-------NKDVTLTSPLLVNL-LQSDISAGHFGVN---NKQNNTNANK 913 Q+ Q+PG P+ ++ T + + +L QS +AG G+ + + T AN Sbjct: 206 QVQL-QHPGTPITVRERRPSQPHTQSGGTIHHLGPQSPAAAGGAGLQPLASPSHITTANL 264 Query: 914 PKKKKPPRKKKNSQQDL---NTPDTRPAGLEEADQPPLPGEQGI-NLDNSGPKLPEFSNR 969 P + + + QQ P RP G E LPG G + P P +R Sbjct: 265 PPQISSIIQGQLVQQQQVLQGPPLPRPLGFERTPGVLLPGAGGAAGFGMTSPPPPTSPSR 324 Query: 970 ---PPGYPSQP---VEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQS 1023 PPG S P V ++++P +L + PP P Q + Q + + Sbjct: 325 TAVPPGLSSLPLTSVGNTGMKKVPKKLEE--IPPASPEMAQMRKQCLDYHYQEMQALKEV 382 Query: 1024 QQQ--------QQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGS 1075 ++ Q Q MM L + K P+ + + + + ++ S Sbjct: 383 FKEYLIELFFLQHFQGNMMDFLAFK---KKHYAPLQAYLRQNDLDIEEEEEEEEEEEEKS 439 Query: 1076 VPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1135 + D+Q + + GS +++ PS+ +AE + P Sbjct: 440 EVIN-------------DEQALAGSLVAGAGSTVETDLFKRQQAMPSTG-MAEQSKRPRL 485 Query: 1136 SGSEAPSV---PGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSS 1192 V PG +P ++P Q G P TPQ + S Sbjct: 486 EVGHQGVVFQHPGADAGVPLQQLMPTAQ--------GGMP------PTPQAAQLAGQRQS 531 Query: 1193 HGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPS-------EISLSPERLN 1245 + P+ P Q N AS PQ P PP+ P+ + + P+ + Sbjct: 532 QQQYDPSTGPPVQ-------NAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVE 584 Query: 1246 ASIAGLFP-----PQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFAT- 1299 A P P + IP PP L Q P L P + + S ++ Sbjct: 585 AQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQ----PAQLALHVPTPGKVQVQASQLSSL 640 Query: 1300 PQTHKLDSVVVNSGKQSNSGATKRASPSNSRRS-SPGSSRKTTPSPGRQNSKAPKLTLAS 1358 PQ + V+ + R P++S S +P S PSP R +P +S Sbjct: 641 PQMVASTRLPVDP-----APPCPRPLPTSSTSSLAPVSGSGPGPSPAR---SSPVNRPSS 692 Query: 1359 QTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVS 1404 TN AL SP P V S P QN+T S Sbjct: 693 ATNKAL------------SPVTSRTPGVVASAPTKPQSPAQNATSS 726 Score = 48.9 bits (115), Expect = 5e-05 Identities = 64/266 (24%), Positives = 98/266 (36%), Gaps = 34/266 (12%) Query: 982 PLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPP--PPSQPQSQQQQQQQQQMMMMLMM 1039 PLQQ+ P + P PQ Q Q Q QQ P PP Q + Q L Sbjct: 504 PLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQ-----LPG 558 Query: 1040 QQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPM 1099 + P V + L Q ++ + + V Q P P+P ++P+ Sbjct: 559 RLPPAGVPTAALSSA------LQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPI 612 Query: 1100 PVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPE-ASGSEAPSVPGGPNNMPSHVVLPQ 1158 P + P ++ ++++SLP+ + + P P P P Sbjct: 613 PPSQP-----AQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTS 667 Query: 1159 NQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPR 1218 + ++G PGPSP ++ PVN PSS N A TSR TP + Sbjct: 668 SLAPVSGSGPGPSPARSS--------PVNR-PSS----ATNKALSPVTSR--TPGVVASA 712 Query: 1219 PYYPQTPNNRPPSTEPSEISLSPERL 1244 P PQ+P S++ S E++ Sbjct: 713 PTKPQSPAQNATSSQDSSQDTLTEQI 738 Score = 45.4 bits (106), Expect = 6e-04 Identities = 62/245 (25%), Positives = 87/245 (35%), Gaps = 32/245 (13%) Query: 231 HPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQ-----QQQQQQQQQQQQ 285 HP P + P + QL Q+Q QQQ Q Q Sbjct: 496 HPGADAGVPLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQ 555 Query: 286 LQARPPQQ-----------HQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGS 334 L R P QQPQ + Q Q+PV +P A PP +Q Sbjct: 556 LPGRLPPAGVPTAALSSALQFAQQPQVVEAQ--TQLQIPVKTQQPNVPIPA--PPSSQLP 611 Query: 335 LGTMTANQGWKKAPLPGPMQQQLQARPSL----ATVQTPSHPPPPYPFGSQQASQAHTNF 390 + Q P PG +Q Q SL A+ + P P PP P + + ++ Sbjct: 612 IPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCP--RPLPTSSTSSL 669 Query: 391 PQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSP---ASSPSSFQQGSPASSPTVN 447 +S G +P S PS P +T+++P AS+P+ Q SPA + T + Sbjct: 670 APVSGSGPGPSPARSSPVNRPSSATNKALSP-VTSRTPGVVASAPTKPQ--SPAQNATSS 726 Query: 448 QTQQQ 452 Q Q Sbjct: 727 QDSSQ 731 Score = 40.8 bits (94), Expect = 0.014 Identities = 80/340 (23%), Positives = 112/340 (32%), Gaps = 51/340 (15%) Query: 901 GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLE-EADQPPLPGEQGINLDNS 959 G+ NK A KKK PRK P RPA + +A + P + G + Sbjct: 1380 GLENKITRHEAELLSKKKIPRKLMEEISTSAAPAARPAAAKLKASRLFQPVQYGQKPEGR 1439 Query: 960 GPKLPEFSNRPP----GYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP 1015 P S PP + Q PL+ PP + + P+ Q Q Sbjct: 1440 TVAFP--STHPPRTAAPTTASAAPQGPLRGRPP--IATFSANPEAKAAAAPFQTSQASAS 1495 Query: 1016 PPPSQPQSQQQQQQQQQMMMMLMMQ---------QDPKSVRLP---VSQNVHPPRGPLNP 1063 P QP S L Q Q P + P Q+ P R L Sbjct: 1496 APRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVLPS 1555 Query: 1064 DSQ-RMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPS 1122 +Q R+P + + + S+ GP S P+ PV + + + + Q + Sbjct: 1556 QAQARLPSGEVVKIAQLASITGPQSRVAQPE-----TPVTLQFQGSKFTLSHSQLRQLTA 1610 Query: 1123 SSPLAEMASLPEASGSEAPSVPGGPN-NMPSHVVLP--------QNQLMMTGPKPGPSPL 1173 PL S+ + S PG P P VV+ L P GPSP Sbjct: 1611 GQPLQLQGSV-----LQIVSAPGQPYLRAPGPVVMQTVSQAGAVHGALGSKPPAGGPSPA 1665 Query: 1174 SAT-QGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTP 1212 T Q P + VN+L V P S+P +P Sbjct: 1666 PLTPQVGVPGRVAVNALA---------VGEPGTASKPASP 1696 Score = 40.4 bits (93), Expect = 0.018 Identities = 61/246 (24%), Positives = 80/246 (32%), Gaps = 69/246 (28%) Query: 297 QQPQGIRPQF--TAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQ 354 Q+P+G F T P + P + P G L+ P + T +AN K A P Sbjct: 1434 QKPEGRTVAFPSTHPPRTAAPTTASAAPQGPLRGRPP---IATFSANPEAKAAAAPFQTS 1490 Query: 355 QQLQARP------SLATVQTPSHP----------------PPPYPFGSQQASQAHTNFPQ 392 Q + P + +T +P+HP PPP P A+ + Sbjct: 1491 QASASAPRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPSHAAGQSALPQR 1550 Query: 393 MSNPGQFTA----------PQMKSLQGGPSRVPTP-----------------LQQPHLTN 425 + P Q A Q+ S+ G SRV P Q LT Sbjct: 1551 LVLPSQAQARLPSGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTA 1610 Query: 426 KSPASSPSSFQQ-----GSP---ASSPTVNQTQQQ-------MGPRPPQNNPLPQGFQQP 470 P S Q G P A P V QT Q +G +PP P P Sbjct: 1611 GQPLQLQGSVLQIVSAPGQPYLRAPGPVVMQTVSQAGAVHGALGSKPPAGGPSPAPLTPQ 1670 Query: 471 VSSPGR 476 V PGR Sbjct: 1671 VGVPGR 1676 Score = 40.0 bits (92), Expect = 0.024 Identities = 90/400 (22%), Positives = 148/400 (37%), Gaps = 50/400 (12%) Query: 413 RVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRP--PQNNPLPQGFQQP 470 ++P L + T+ +PA+ P++ + + V Q+ G P +P Sbjct: 1397 KIPRKLMEEISTSAAPAARPAAAKLKASRLFQPVQYGQKPEGRTVAFPSTHPPRTAAPTT 1456 Query: 471 VSSPGRNPMVQQGNVP-PNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFM 529 S+ + P+ +G P F + P P+ P S+ A+P Sbjct: 1457 ASAAPQGPL--RGRPPIATFSANPEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHP 1514 Query: 530 QGQVPSTTA--TTPGNSGAPQLQANQNVQHAGGQGAGPPQ----NQMQVSHGPPNMMQ-P 582 TTA +TPG PQ QA HA GQ A P + +Q Q +++ Sbjct: 1515 AKLRAQTTAQASTPGQP-PPQPQAPS---HAAGQSALPQRLVLPSQAQARLPSGEVVKIA 1570 Query: 583 SLMGIHGNMNNQQAGTSGVP------QVNLSNMQ-GQPQQGPPSQLMGMHQQIVPSQGQM 635 L I G + + V + LS+ Q Q G P QL G QIV + GQ Sbjct: 1571 QLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQP 1630 Query: 636 VQQQGTLNPQNPMILSRAQL--MPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMA 693 L P+++ G + PP+ GPSP +TP + P +A Sbjct: 1631 Y-----LRAPGPVVMQTVSQAGAVHGALGSKPPAG--GPSPAPLTPQVGV-----PGRVA 1678 Query: 694 PHNQMMGPQGQVLLQQNPM---IEQIMTNQMQGNKQQFNTQNQSNVMPGPA---QIMRGP 747 + +G G +P+ ++ T ++ Q N+ P ++R Sbjct: 1679 VNALAVGEPGTASKPASPIGGPTQEEKTRLLKERLDQIYLVNERRCSQAPVYGRDLLRIC 1738 Query: 748 TPNMQGNMVQFTGQMSGQMLPQQGPVNN------SPSQVM 781 G VQ+ G + G+ + GP ++ SPS++M Sbjct: 1739 ALPSHGR-VQWRGSLDGRRGKEAGPAHSYTSSSESPSELM 1777 Score = 39.3 bits (90), Expect = 0.040 Identities = 53/218 (24%), Positives = 83/218 (38%), Gaps = 39/218 (17%) Query: 1620 LQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIP 1679 L+ V P A + V + + AQ P TP + Q + PST P Sbjct: 485 LEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPP---TPQAAQLAGQRQSQQQYDPSTGP 541 Query: 1680 AAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSS----PAPNI---QTGRPL 1732 P+ + L P + G L A VP ALSS+ P + QT + Sbjct: 542 --PVQNAASLHTPLPQLPGRL--------PPAGVPTAALSSALQFAQQPQVVEAQTQLQI 591 Query: 1733 VLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSAD------------ 1780 + ++ V +P+PP + P+ PS P + P + Q + + Sbjct: 592 PVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPV 651 Query: 1781 ------QNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVS 1812 LP+S ST+ ++P+ + PG S R SPV+ Sbjct: 652 DPAPPCPRPLPTS-STSSLAPVSGSGPGPSPARSSPVN 688 Score = 33.5 bits (75), Expect = 2.2 Identities = 80/388 (20%), Positives = 136/388 (35%), Gaps = 40/388 (10%) Query: 1445 PAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNV- 1503 P Q+ +P+ Q+ P+ P + + + P +AP + G+ V Sbjct: 2516 PPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVL 2575 Query: 1504 --TIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVH 1561 TIK +T + VSG ++ T+ + ++ S + L S +L Sbjct: 2576 AGTIKT-SVTGTSMPTGAVSGN-----VIVNTIAGVPAATFQSINKRLA-SPVAPGALTT 2628 Query: 1562 PELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITV-------FVTSNPITTSANTSA 1614 P S + V PP R V S + +TP + T VT++ + T+ T Sbjct: 2629 PGGSAPAQVVHTQPPP---RAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPV 2685 Query: 1615 ALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQ 1674 P +S + G + + Q Q + Q Q + Q Sbjct: 2686 QTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQ 2745 Query: 1675 PSTIPAA----PLTTNSGLMPPSVAVVG---PLHI----PQNIKFSSAPVPPNALSSSPA 1723 T + P P + VG P H+ Q ++ P PP A S+ P Sbjct: 2746 QQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQ 2805 Query: 1724 P----NIQTGR-PLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPD--EASPQVN 1776 P +QT + P S + T V P P + ++ V ++ + +A Q+ Sbjct: 2806 PTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQ 2865 Query: 1777 TSADQNTLPSSQSTTMVS--PLLTNSPG 1802 T A Q + +VS + +SPG Sbjct: 2866 TQAPQPAQVALAKPPVVSVPAAVVSSPG 2893 Score = 31.6 bits (70), Expect = 8.4 Identities = 49/195 (25%), Positives = 78/195 (40%), Gaps = 28/195 (14%) Query: 1576 PPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAG 1635 PPV + ++S+ TPLP + + +AAL + LQ A VV Sbjct: 541 PPVQN----AASLHTPLPQ-------LPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQ- 588 Query: 1636 SKVMVSEGQSAAQSNARPQFITPV----------FINSSSIIQVMKGSQPSTIPAAPLTT 1685 ++ V Q A P P+ + + +QV + SQ S++P +T Sbjct: 589 LQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQV-QASQLSSLPQMVAST 647 Query: 1686 NSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRA-TPVQLP 1744 +P A P +P + S APV + SPA + RP +++A +PV Sbjct: 648 R---LPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSATNKALSPVTSR 704 Query: 1745 SP-PCTSSPVVPSHP 1758 +P S+P P P Sbjct: 705 TPGVVASAPTKPQSP 719 >gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] Length = 788 Score = 96.7 bits (239), Expect = 2e-19 Identities = 110/350 (31%), Positives = 139/350 (39%), Gaps = 53/350 (15%) Query: 226 IQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQ 285 +QQQ L HH Q +Q QLQ QQQQQQQQQQQQQQQQ Q Q Sbjct: 210 LQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPP 269 Query: 286 LQARPPQQHQQQQPQGIRPQFTAP---TQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQ 342 +Q +PP Q Q P PQ TQ PP Q P A Q P+Q + T Sbjct: 270 IQ-QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA-QNQPSQLPPQSQTQPL 327 Query: 343 GWKKAPLPGPMQQQLQARPSLATVQTPS--HPPPPYPFGSQQASQAHTNFPQMSNPGQFT 400 + LPG Q L +P L V+ P PP P QQ + T + Q Sbjct: 328 VSQAQALPG---QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQT-----AQAAQMV 379 Query: 401 APQMKSL-----QGG------------PSRVPT---PLQQPHLTNKSPASSPSSFQQGSP 440 AP ++ + QGG S +P+ PL + + S +S P SP Sbjct: 380 APGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLP---MLSSP 436 Query: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQG 500 + V QT Q M P PPQ +P P QP S P N P +F+ P+Q Sbjct: 437 SPGQQV-QTPQSM-PPPPQPSPQP---GQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQS 491 Query: 501 PQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQ 550 P + R P FS P PS+ + G+S A + Q Sbjct: 492 P---------VTARTPQNFSVPSPGP-LNTPVNPSSVMSPAGSSQAEEQQ 531 Score = 90.1 bits (222), Expect = 2e-17 Identities = 135/478 (28%), Positives = 172/478 (35%), Gaps = 79/478 (16%) Query: 142 NRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSS-----SMMA 196 N+ ++ PM A S+ G P A GI +PP G S S+ A Sbjct: 71 NKKSQASVSDPMNALQSL---TGGPAAGAAGI---------GMPPRGPGQSLGGMGSLGA 118 Query: 197 PGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPAN 256 G +P S S P SG+ + S + +Q V++ +Q Sbjct: 119 MG----------QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQ 168 Query: 257 FPQLQQQQQQQQQQQQQQQQQQQQQ--QQQQLQARPPQQ---HQQQQPQGIRPQFTAPTQ 311 F Q QQ QQQQQQQQQQQ Q QQ QQQ QA QQ QQQQ Q + Q Sbjct: 169 FQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQ 228 Query: 312 VPVPPGWNQLPSGA---LQPPPAQGSLGTMTANQGWK-KAPLPGPMQQQLQARPSLATVQ 367 + QL A LQ Q Q + + P+ P QQ Q PS A Q Sbjct: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQ 288 Query: 368 -------TPSHPPPPYPFGSQQASQAHTNFPQMSN-----------PGQ--FTAPQMKSL 407 T H PPP P A + P S PGQ +T P +K + Sbjct: 289 QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFV 348 Query: 408 QGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGF 467 + P V P QP + + A + Q + + Q G P Sbjct: 349 R-APMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAV 407 Query: 468 QQPVSSP---GRNPMVQ--QGNVPPNFMVMQQQPPN--QGPQSLHPGLGGMPKRLPPGFS 520 SS GR PM Q Q ++P M+ P Q PQS+ P P+ PG Sbjct: 408 SAIPSSSIPLGRQPMAQVSQSSLP---MLSSPSPGQQVQTPQSMPPPPQPSPQ---PGQP 461 Query: 521 AGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPN 578 + Q N N G PS ++ P S P A PQN S GP N Sbjct: 462 SSQPNSNVSSGPAPSPSSFLPSPSPQPS---------QSPVTARTPQNFSVPSPGPLN 510 Score = 65.1 bits (157), Expect = 7e-10 Identities = 89/361 (24%), Positives = 123/361 (34%), Gaps = 45/361 (12%) Query: 976 QPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQ----------- 1024 Q +Q LQQ Q Q Q QQ + QQQQ Q Q Q Sbjct: 170 QQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQ 229 Query: 1025 QQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQG 1084 Q QQQQQQ+ + +Q + + Q P Q+ PMQQ P Q Sbjct: 230 QIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQ 289 Query: 1085 PASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSS-----PLAEMASLPEASGSE 1139 + + Q P P P+ N + +S P S P + + P Sbjct: 290 LQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVR 349 Query: 1140 APSVPGGPNNMP--------------SHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPP 1185 AP V P P + +V P Q++ G + A P Sbjct: 350 APMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRA---RFPPTTA 406 Query: 1186 VNSLPSSHGHHFPNVAAP-TQTSRPKTPNRASPRP-YYPQTPNNRPPSTEPSEISLSPE- 1242 V+++PSS P P Q S+ P +SP P QTP + PP +PS P Sbjct: 407 VSAIPSS---SIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSS 463 Query: 1243 --RLNASIAGLFPPQINIPLP-PRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFAT 1299 N S P +P P P+P+ + P P N +NPS+ + Sbjct: 464 QPNSNVSSGPAPSPSSFLPSPSPQPSQS---PVTARTPQNFSVPSPGPLNTPVNPSSVMS 520 Query: 1300 P 1300 P Sbjct: 521 P 521 Score = 60.1 bits (144), Expect = 2e-08 Identities = 153/703 (21%), Positives = 240/703 (34%), Gaps = 101/703 (14%) Query: 924 KNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPL 983 K SQ ++ P L+ P G GI + GP G QP+ L Sbjct: 72 KKSQASVSDPMN---ALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMS---L 125 Query: 984 QQMPPQLMQHVAP---------PPQPP---------QQQPQPQLPQQQQPPPPSQPQSQQ 1025 PP +AP PQ QQQ Q Q QQQQ Q Q QQ Sbjct: 126 SGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAA--LQQQQQQ 183 Query: 1026 QQQQQQQMMMMLMMQQDPKSV----RLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVS 1081 QQQQQ Q M QQ V +L Q L+ +Q+ QQ + + Sbjct: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ 243 Query: 1082 L---QGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGS 1138 L Q +Q+ + P+ + + PQ P S L + L + + Sbjct: 244 LQLQQQQQQQQQQQQQQQQALQAQPPI-----QQPPMQQPQPPPSQALPQ--QLQQMHHT 296 Query: 1139 EAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP 1198 + P P P + QNQ P+ PL + A P Q P Sbjct: 297 QHHQPPPQPQQPP----VAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKF----- 347 Query: 1199 NVAAPTQTSRPKTPNRASPRPYYPQTPNNR---PPSTEPSEISLSPERLNASIAGLFPPQ 1255 V AP +P + + QT P + +L+ ++ I FPP Sbjct: 348 -VRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMH--IRARFPPT 404 Query: 1256 INIPLPPRPNLNRGFDQQG-LNPTTLKAIGQ-APSNLTMNPSNFATPQTHKLDSVVVNSG 1313 + P ++ G ++ ++L + +P P + P +S Sbjct: 405 TAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ 464 Query: 1314 KQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRN 1373 SN + SPS+ PSP Q S++P A QN +P Sbjct: 465 PNSNVSSGPAPSPSS-----------FLPSPSPQPSQSP-------VTARTPQNFSVP-- 504 Query: 1374 VLVSPTPLANPPVPGSFPNNSG---LNPQNSTVSVAAVGGVVED-----NKESLNVPQDS 1425 SP PL P P S + +G Q + + +E NK N + Sbjct: 505 ---SPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKK 561 Query: 1426 DCQNSQSRKEQVNIELKAVPAQEV-KMVVPEDQSKKD-GQPSDPNKLPSVEENKNLVSPA 1483 D +S + + K P + + K + ++ K D P+ P + + L P Sbjct: 562 DLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPL 621 Query: 1484 MREAPTSLSQLLDNSGAPNVTIKPPGLTDLE---VTPPVVSG-----EDLKKASVIPTLQ 1535 + ++ + N + P +T + +T PVV ED ++ S+ LQ Sbjct: 622 LDAVLANIRSPVFNHSLYRTFV--PAMTAIHGPPITAPVVCTRKRRLEDDERQSIPSVLQ 679 Query: 1536 DLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPV 1578 + +P +NL S+ + VH + ++ PS+PP+ Sbjct: 680 GEVARLDPKFLVNLDPSHCSNNGTVH-LICKLDDKDLPSVPPL 721 Score = 53.5 bits (127), Expect = 2e-06 Identities = 95/419 (22%), Positives = 134/419 (31%), Gaps = 52/419 (12%) Query: 425 NKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQG----FQQPVSSPGRNPMV 480 +++ S P + Q S P M PR P + G QP+S G+ P Sbjct: 74 SQASVSDPMNALQ-SLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPG 132 Query: 481 QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT 540 G P + V+ P Q L Q Q Q + Sbjct: 133 TSGMAPHSMAVVSTATPQTQLQLQQVAL------------QQQQQQQQFQQQQQAALQQQ 180 Query: 541 PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGN----MNNQQA 596 Q QA Q+ Q Q Q+Q Q L+ +H + QQ Sbjct: 181 QQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQ----QQQQHLIKLHHQNQQQIQQQQQ 236 Query: 597 GTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLM 656 + Q+ L Q Q QQ Q + Q Q M Q Q P + + + Q M Sbjct: 237 QLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQ---PPPSQALPQQLQQM 293 Query: 657 PQGQMMVNPPSQNLGPSPQR---MTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMI 713 Q PP P Q PP+ Q A QM+ Q + + PM+ Sbjct: 294 HHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMV 353 Query: 714 EQIMTNQMQGNKQQF---NTQNQSNVMPGPAQIMRG-------------PTPNMQ---GN 754 Q Q Q +QQ Q V PG I PT + + Sbjct: 354 VQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSS 413 Query: 755 MVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVS 813 + Q Q+ P+ +SPS +Q PP P P + Q G P++ N++VS Sbjct: 414 SIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP--SPQPGQPSSQPNSNVS 470 Score = 52.8 bits (125), Expect = 4e-06 Identities = 116/502 (23%), Positives = 161/502 (32%), Gaps = 94/502 (18%) Query: 556 QHAGGQGA-GPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQ 614 Q GG G+ G M +S PP P G+ + + ++ PQ L Q Q Sbjct: 108 QSLGGMGSLGAMGQPMSLSGQPP----PGTSGMAPH--SMAVVSTATPQTQLQLQQVALQ 161 Query: 615 QGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSP 674 Q Q QQ Q Q QQQ Q + + Q + Q Q + Sbjct: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQ---------- 211 Query: 675 QRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQS 734 +Q QQ + NQ Q Q LQ+ ++ Q Q +QQ Q Sbjct: 212 ------QQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQ 265 Query: 735 NVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQM------LPQQGPV-NNSPSQV------- 780 P M+ P P + Q QM PQQ PV N PSQ+ Sbjct: 266 AQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325 Query: 781 -MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQT--------NMVPP 831 + Q Q L P + Q A V + P V QQT MV P Sbjct: 326 PLVSQAQAL----PGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAP 381 Query: 832 HVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLL 891 VQ + A G GM A F P +S + P+ + + + Sbjct: 382 GVQMITEALAQG------GMHIRARF---PPTTAVSAIPSSSIPLGRQP------MAQVS 426 Query: 892 QSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGE 951 QS + P + Q + TP + P + + QP P Sbjct: 427 QSSL-----------------------PMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSS 463 Query: 952 QGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQ 1011 Q + +SGP S P PS Q P+ PQ +P P P + Sbjct: 464 QPNSNVSSGPAPSPSSFLPS--PSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVM-- 519 Query: 1012 QQQPPPPSQPQSQQQQQQQQQM 1033 P SQ + QQ + +Q+ Sbjct: 520 --SPAGSSQAEEQQYLDKLKQL 539 Score = 45.4 bits (106), Expect = 6e-04 Identities = 93/486 (19%), Positives = 169/486 (34%), Gaps = 66/486 (13%) Query: 1378 PTPLANPPVPGSFPNNSGLNPQNSTVSVAA----------VGGVVEDNKESLNVPQDSDC 1427 P L+ P PG+ SG+ P + V A V + ++ Q + Sbjct: 122 PMSLSGQPPPGT----SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL 177 Query: 1428 QNSQSRKEQVNIELK-AVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMRE 1486 Q Q +++Q + + + Q+ + VV + Q + Q + + +N+ + ++ Sbjct: 178 QQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQ 237 Query: 1487 APTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNS 1546 L + L+ PP+ P +Q +P S Sbjct: 238 LQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ----------PPMQQ----PQPPPS 283 Query: 1547 LNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPI 1606 LP +L ++ PP +P + + + LPP T P+ Sbjct: 284 QALPQ-----------QLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQT-----QPL 327 Query: 1607 TTSANTSAALPTHLQSALMST----VVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFIN 1662 + A + Q L VV P + V + Q+A Q+ Q + P Sbjct: 328 VSQAQALPGQMLYTQPPLKFVRAPMVVQQPPV--QPQVQQQQTAVQTAQAAQMVAP---G 382 Query: 1663 SSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSP 1722 I + + P TT +P S +G + Q + SS P + SSP Sbjct: 383 VQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQ-VSQSSLP-----MLSSP 436 Query: 1723 APNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQN 1782 +P Q P + P P P + S P P SP S Sbjct: 437 SPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLP---SPSPQPSQSPV 493 Query: 1783 TLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGK--VDKIGQI-LLTKACKKVTGSL 1839 T + Q+ ++ SP N+P + + SP SS+ + + +DK+ Q+ + +++ + Sbjct: 494 TARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKI 553 Query: 1840 EKGEEQ 1845 +K E++ Sbjct: 554 DKNEDR 559 >gi|38158015 mastermind-like 3 [Homo sapiens] Length = 1133 Score = 95.9 bits (237), Expect = 4e-19 Identities = 183/786 (23%), Positives = 254/786 (32%), Gaps = 145/786 (18%) Query: 166 PMASGPGIIRMNN----PATVMIPPGGNVSSS---MMAPGPNPELQPRTPRPASQSDAMD 218 P +SGP ++ P+ P N +SS P Q TP A Sbjct: 378 PSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNG 437 Query: 219 PLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQ 278 LL+ + SG +A P M P QL+Q QQQQ+ + QQ+Q Sbjct: 438 YLLNPAAVTVAGSASGPVAVPSSDMSPAE-----------QLKQMAAQQQQRAKLMQQKQ 486 Query: 279 QQQQQQQLQARPPQQHQQQQPQGIRPQFT--APTQVPVPPGWN-QLPSGALQPPPAQGSL 335 QQQQQQQ Q + QQ QQQQ ++ P P + + P+ + P A + Sbjct: 487 QQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNN- 545 Query: 336 GTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSH----PPPPYPFGSQQASQAHTNFP 391 + P+ PM LQ + ++ +H P G+ ++ H N Sbjct: 546 ----------QNPIVPPMANNLQ-KTTMNNYLPQNHMNMINQQPNNLGTNSLNKQH-NIL 593 Query: 392 QMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQ 451 N T P R+ P+ P NK+P QQ Q QQ Sbjct: 594 TYGN----TKPLTHFNADLSQRMTPPVANP---NKNPLMPYIQQQQ----------QQQQ 636 Query: 452 QMGPRPPQNNPLPQGFQQPVSSPGRNP-----MVQQG--NVPPNFMVMQQQPPNQGPQSL 504 Q + Q P P Q P + + M Q+G N P + + Q P L Sbjct: 637 QQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGL 696 Query: 505 HPGLGGMPKRLPPG-----FSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAG 559 G M +PPG A A P F+ Q + QL Q Q Sbjct: 697 PRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLR 756 Query: 560 GQGAGPPQ-------NQMQVSHGPPNMMQP------------------SLMGIHGNMNNQ 594 Q Q Q+Q SH P +QP + + Q Sbjct: 757 EQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQ 816 Query: 595 QAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQ---IVPSQGQMVQQQGTLNPQNPMILS 651 TS + N M P Q P + Q + P Q G N M Sbjct: 817 SMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMT-- 874 Query: 652 RAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMA--------------PHNQ 697 QM+ +P + + + P+Q S QG M++ H Q Sbjct: 875 --------QMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQ 926 Query: 698 MMGPQGQVL--LQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPN----- 750 M GP GQ L Q P ++ +M QG Q Q MPG GP N Sbjct: 927 MKGPVGQALPRPQAPPRLQSLMGTVQQG--AQSWQQRSLQGMPGRTSGELGPFNNGASYP 984 Query: 751 MQGNMVQFTGQMSGQMLPQQ------GPVNNSPSQVMGIQGQVLRPPGPSPHMAQ----- 799 +Q + T Q Q L Q G V MG Q P A+ Sbjct: 985 LQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARPMVMS 1044 Query: 800 --QHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPF 857 G P A + Q +P S ++ QA + N+ ++ G F Sbjct: 1045 GLSQGVPGMPAFSQPPAQQQIPSGSFAPSS----QSQAYERNAPQDVSYNYSGDGAGGSF 1100 Query: 858 SGAPNG 863 G P+G Sbjct: 1101 PGLPDG 1106 Score = 50.4 bits (119), Expect = 2e-05 Identities = 77/353 (21%), Positives = 113/353 (32%), Gaps = 44/353 (12%) Query: 913 KPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPG 972 +P PP ++ L + + PA P P N P+ P ++ P Sbjct: 377 RPSSSGPPFSTVSTATSLPSVASTPAA-------PNPASSPANCAVQSPQTPNQAHTPGQ 429 Query: 973 YPSQPVEQRPLQQMPPQLMQHVAPP------PQPPQQQPQPQLPQQQQPPPPSQPQSQQQ 1026 P +P L + + P P +Q + QQQQ Q + QQQ Sbjct: 430 APPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQ 489 Query: 1027 QQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPA 1086 QQQQQQ QQ S + + PP P P + Q P Sbjct: 490 QQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPI 549 Query: 1087 SVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASL-------------P 1133 P + + Q+ M N L N M+ Q+ P N ++ L + ++ Sbjct: 550 VPPMANNLQKTTM--NNYLPQNHMNMINQQ-PNNLGTNSLNKQHNILTYGNTKPLTHFNA 606 Query: 1134 EASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSH 1193 + S P V PN P + Q Q Q QQPP L + Sbjct: 607 DLSQRMTPPV-ANPNKNPLMPYIQQQQQQQQ---------QQQQQQQQQQPPPPQLQAPR 656 Query: 1194 GHHFPNVAAPTQTSRPKTPNR-----ASPRPYYPQTPNNRPPSTEPSEISLSP 1241 H + + N+ A P Q P P +T P + S+ P Sbjct: 657 AHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPP 709 Score = 50.1 bits (118), Expect = 2e-05 Identities = 156/750 (20%), Positives = 248/750 (33%), Gaps = 147/750 (19%) Query: 639 QGTLNPQNPMILSRAQLMPQGQMM--VNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHN 696 Q P N +L+ A + G V PS ++ P+ Q KQM +QQ Sbjct: 429 QAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQL----KQMAAQQ--------- 475 Query: 697 QMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMV 756 Q + L Q +Q Q Q +QQ Q SN + + GP + G Sbjct: 476 -----QQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPL--GPPSSPYGAAF 528 Query: 757 QFTGQMSGQMLPQ----QGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDV 812 S M PQ Q P+ P +Q + P HM + P N + Sbjct: 529 TAEKPNSPMMYPQAFNNQNPI--VPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSL 586 Query: 813 SLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNP 872 + +Q N++ GN+ HF+ P PN N Sbjct: 587 N----------KQHNILT------YGNTKPLTHFNADLSQRMTPPVANPNKN-------- 622 Query: 873 GFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNT 932 PL+ + Q +Q + +++ PP + + + L+ Sbjct: 623 ------------PLMPYIQQQQ---------QQQQQQQQQQQQQQPPPPQLQAPRAHLS- 660 Query: 933 PDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGY---PSQPVEQRPL------ 983 E+ + L ++G+ N+P Y PS EQ P+ Sbjct: 661 --------EDQKRLLLMKQKGV------------MNQPMAYAALPSHGQEQHPVGLPRTT 700 Query: 984 ----QQMPPQL--MQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML 1037 +PP M A P P QPQ +Q + Q +QQ+QQ Sbjct: 701 GPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQ 760 Query: 1038 MMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQ----SGSVPVMVSLQGPASVPPSPD 1093 QQ + + Q H PR L P P+QQ GS + +++ A++ Sbjct: 761 QQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAAL----- 815 Query: 1094 KQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSH 1153 M + + N+ M S + + A + + A S P+ G NM + Sbjct: 816 ---QSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTG 872 Query: 1154 VVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVN---SLPSSHGHH-FPNVAAPTQTSRP 1209 + M+ P ++ Q P+QP + S G N A Q + Sbjct: 873 MT-----QMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQM 927 Query: 1210 KTP-NRASPRPYYPQ-------TPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLP 1261 K P +A PRP P T S + + P R + + G F + PL Sbjct: 928 KGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGEL-GPFNNGASYPLQ 986 Query: 1262 P-RPNLNRGFDQQGL-------NPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSG 1313 +P L + QGL N T++ + A M PS T + +V++ Sbjct: 987 AGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARPMVMSGL 1046 Query: 1314 KQSNSGATKRASPSNSRRSSPGSSRKTTPS 1343 Q G + P ++ GS ++ S Sbjct: 1047 SQGVPGMPAFSQPPAQQQIPSGSFAPSSQS 1076 Score = 35.0 bits (79), Expect = 0.76 Identities = 68/320 (21%), Positives = 114/320 (35%), Gaps = 50/320 (15%) Query: 1488 PTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASV-IPTLQDLSSSKEPSNS 1546 P L L N P + + G +DLE + ++ +DLK+ + PT D S + Sbjct: 237 PGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSET------ 290 Query: 1547 LNLPHSNELCS--SLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSN 1604 +L + N+L S +L E E+ +A ++P + + + P + + T Sbjct: 291 -SLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEP-EFSQPATET 348 Query: 1605 PITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSS 1664 P++ + + + P+H A + S ARP P F S Sbjct: 349 PLSQESASVKSDPSHSPFAHV-------------------SMGSPQARPSSSGPPFSTVS 389 Query: 1665 SIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQ-NIKFSSAPVPPNALSSSPA 1723 + S PS + + P N P + AV P Q + + P P N +PA Sbjct: 390 TAT-----SLPS-VASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPA 443 Query: 1724 PNIQTGRPLVLSSRATPVQLPSPPCTSSPVV-------PSHPPVQQVKELNPDEASPQVN 1776 V S + PV +PS + + + + Q K+ + Q Sbjct: 444 ------AVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQ 497 Query: 1777 TSADQNTLPSSQSTTMVSPL 1796 Q S T+ SPL Sbjct: 498 QQQQQQQQQHSNQTSNWSPL 517 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 94.7 bits (234), Expect = 8e-19 Identities = 212/1014 (20%), Positives = 330/1014 (32%), Gaps = 141/1014 (13%) Query: 961 PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ 1020 P P + PP P+ P P PPP P P + PPP + Sbjct: 1399 PSPPTTTPSPP--PTSTTTLPPTTTPSPPTTTTTTPPPTTT---PSPPITTTTTPPPTTT 1453 Query: 1021 PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPP--RGPLNPDSQRMPMQQSGSVPV 1078 P P+S PP P P + P + S P Sbjct: 1454 PSP-------------------------PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPT 1488 Query: 1079 MVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGS 1138 + P + PSP P TP+ + P + SP + P + + Sbjct: 1489 TTTTTPPPTTTPSP-------PTTTPITPPASTTTL---PPTTTPSPPTTTTTTPPPTTT 1538 Query: 1139 EAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP 1198 +P S LP T P P P+ + T PP + PS P Sbjct: 1539 PSPPTTTPITPPTSTTTLPPT----TTPSPPPTTTTTPPPTTTPSPPTTTTPSP-----P 1589 Query: 1199 NVAA----PTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNAS---IAGL 1251 + PT T P T +P P +P P T P+ + P S Sbjct: 1590 TITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1649 Query: 1252 FPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN-LTMNPSNFATPQTHKLDSVVV 1310 PP P PP + TT PS+ +T PS T T + Sbjct: 1650 TPPPTTTPSPPTTTT----PSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTT- 1704 Query: 1311 NSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVEL 1370 +S T +PS++ SP + TTPSP S P T+ + L Sbjct: 1705 -----PSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS-PPTTTMTT-----------L 1747 Query: 1371 PRNVLVSP---TPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVP-QDSD 1426 P SP TPL P +F S P V + G ++ K + + P D++ Sbjct: 1748 PPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTE 1807 Query: 1427 CQNSQSRKE-QVNIELKA-----VPAQEVKMVVPEDQS------KKDGQPSDPNKLP-SV 1473 NI +A VP ++ V D S +D +P + + Sbjct: 1808 LIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCL 1867 Query: 1474 EENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTP-PVVSGEDLKKASVIP 1532 N+ PT+++ + P T P T VTP P +G + I Sbjct: 1868 NYEINVQCCECVTQPTTMTTTTTENPTPPTT--TPITTTTTVTPTPTPTGTQTPTTTPIT 1925 Query: 1533 TLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPL 1592 T ++ + P+ + P + + ++ + P+ + P+++++ TP Sbjct: 1926 TTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPT 1979 Query: 1593 PPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNAR 1652 P T T+ PITT T+ PT + + T + V + + Q+ Sbjct: 1980 PTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2036 Query: 1653 PQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAP 1712 T + + G+Q T TT P P P + P Sbjct: 2037 TPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2093 Query: 1713 VPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEAS 1772 P + +P T P+ ++ TP P+P T +P P+ + P + Sbjct: 2094 TPTPTGTQTP-----TTTPITTTTTVTPT--PTPTGTQTPTT---TPITTTTTVTP---T 2140 Query: 1773 PQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKV-DKIGQILLTKA 1831 P + T P + +TT V+P T + G+ +P++++ G T Sbjct: 2141 PTPTGTQTPTTTPIT-TTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2198 Query: 1832 CKKVTGSLEKGEEQYGADGETEGQGLDTT----APGLMGTEQLS----TELDSKTPTP-P 1882 T ++ G T TT P GT+ + T + TPTP P Sbjct: 2199 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2258 Query: 1883 APTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLV---PSELISAVPTT 1933 T T+ T + P+ G PT+ TT V P+ + PTT Sbjct: 2259 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2312 Score = 65.9 bits (159), Expect = 4e-10 Identities = 135/756 (17%), Positives = 247/756 (32%), Gaps = 63/756 (8%) Query: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESP---QNPSSSP 1125 P P + +V P+P P TP+ + + + +P Q P+++P Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTP 3579 Query: 1126 LAEMASL---PEASGSEAPSVPG-------GPNNMPSHVVLPQNQLMMTGPKPGPSPLSA 1175 + ++ P +G++ P+ P P+ P + T P+P + Sbjct: 3580 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TP 3638 Query: 1176 TQGATPQQPPVNSL------PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 T TP P+ + P+ G P P T+ TP +P P QTP P Sbjct: 3639 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTP---TPTPTGTQTPTTTP 3694 Query: 1230 PSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN 1289 +T + ++ +P P + P P PTT Sbjct: 3695 ITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVT 3748 Query: 1290 LTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKT-TPSPGRQN 1348 T P+ TP T + + + + +G +P+ + ++ + T TP+ + Sbjct: 3749 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTP 3805 Query: 1349 SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAV 1408 + P T + T + P ++ T P + P +T +V Sbjct: 3806 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3865 Query: 1409 GGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 + P + + + P V P P+ Sbjct: 3866 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-T 3923 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT-------IKPPGLTDLEVTP-PVV 1520 + + +P + PT+ + P T P T VTP P Sbjct: 3924 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3983 Query: 1521 SGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS 1580 +G + I T ++ + P+ + P + + ++ + P+ + Sbjct: 3984 TGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPT-----T 4037 Query: 1581 RPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMV 1640 P+++++ TP P T T+ PITT T+ PT + + T + V Sbjct: 4038 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 4094 Query: 1641 SEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPL 1700 + + Q+ T + + G+Q T TT P P Sbjct: 4095 TPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4151 Query: 1701 HIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPV 1760 P + P P + +P T P+ ++ TP P+ T P S P+ Sbjct: 4152 TTPITTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPI 4206 Query: 1761 QQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPL 1796 ++ NP S TS ++ P ++STT++S L Sbjct: 4207 AELTTSNPPPESSTPQTSRSTSS-PLTESTTLLSTL 4241 Score = 61.2 bits (147), Expect = 1e-08 Identities = 139/784 (17%), Positives = 259/784 (33%), Gaps = 67/784 (8%) Query: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESP---QNPSSSP 1125 P P + +V P+P P TP+ + + + +P Q P+++P Sbjct: 3544 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTP 3602 Query: 1126 LAEMASL---PEASGSEAPSVPG-------GPNNMPSHVVLPQNQLMMTGPKPGPSPLSA 1175 + ++ P +G++ P+ P P+ P + T P+P + Sbjct: 3603 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TP 3661 Query: 1176 TQGATPQQPPVNSL------PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 T TP P+ + P+ G P P T+ TP +P P QTP P Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTP---TPTPTGTQTPTTTP 3717 Query: 1230 PSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN 1289 +T + ++ +P P + P P PTT Sbjct: 3718 ITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVT 3771 Query: 1290 LTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKT-TPSPGRQN 1348 T P+ TP T + + + + +G +P+ + ++ + T TP+ + Sbjct: 3772 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTP 3828 Query: 1349 SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAV 1408 + P T + T + P ++ T P + P +T +V Sbjct: 3829 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3888 Query: 1409 GGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 + P + + + P V P P+ Sbjct: 3889 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-T 3946 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT-------IKPPGLTDLEVTP-PVV 1520 + + +P + PT+ + P T P T VTP P Sbjct: 3947 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4006 Query: 1521 SGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS 1580 +G + I T ++ + P+ + P + + ++ + P+ + Sbjct: 4007 TGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPT-----T 4060 Query: 1581 RPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMV 1640 P+++++ TP P T T+ PITT T+ PT + + T + V Sbjct: 4061 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 4117 Query: 1641 SEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQ-PSTIPAAPLTTNSGLMPPS---VAV 1696 + + Q+ T + + G+Q P+T P TT + P+ Sbjct: 4118 TPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4174 Query: 1697 VGPLHIPQNIKFSSAPV-----PPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCT-S 1750 P+ + + P PP S++P + T P SS + S P T S Sbjct: 4175 TTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES 4234 Query: 1751 SPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSP 1810 + ++ + PP ++ P T++ +TL STT P ++G+ +P Sbjct: 4235 TTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP 4294 Query: 1811 VSSS 1814 S+ Sbjct: 4295 TPST 4298 Score = 57.4 bits (137), Expect = 1e-07 Identities = 91/421 (21%), Positives = 151/421 (35%), Gaps = 50/421 (11%) Query: 1525 LKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVS 1584 + K P+ + S P+++ LP + ++ +P I + P + Sbjct: 1392 MDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPT 1451 Query: 1585 SSSISTPLPPNQITVFVTSNPITTSA--NTSAALPTHLQSALMSTVVTMPNAGSKVMVSE 1642 + TP PP I+ T P TT + T+ + PT S +T T P Sbjct: 1452 T----TPSPP--ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPT-------- 1497 Query: 1643 GQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMP---PSVAVVGP 1699 + P TP+ +S+ P+T P+ P TT + P PS P Sbjct: 1498 ------TTPSPPTTTPITPPASTTTL-----PPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1546 Query: 1700 LHIPQN---IKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPS 1756 + P + + ++ P PP +++P P P + + +PP T++P P+ Sbjct: 1547 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPT 1606 Query: 1757 HPPVQQVKELNPDEAS------PQVNTSADQNTLPSSQSTTMVS--PLLTNSPGSSGNRR 1808 P + P T+ T PS TT + P T SP ++ Sbjct: 1607 TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666 Query: 1809 SPV-SSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGT 1867 P+ +++ I T + T + + T TT P T Sbjct: 1667 PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPT 1726 Query: 1868 EQLSTELDSKTPTPPAPTLLKM----TSSPVGPGTASAGPSL-PGGALPTSVRSIVTTLV 1922 ++T + TP+PP T+ + TSSP+ T PS+ P P S + T V Sbjct: 1727 -TMTTPSPTTTPSPPTTTMTTLPPTTTSSPL--TTTPLPPSITPPTFSPFSTTTPTTPCV 1783 Query: 1923 P 1923 P Sbjct: 1784 P 1784 Score = 55.1 bits (131), Expect = 7e-07 Identities = 165/906 (18%), Positives = 294/906 (32%), Gaps = 85/906 (9%) Query: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESP---QNPSSSP 1125 P P + +V P+P P TP+ + + + +P Q P+++P Sbjct: 1934 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTP 1992 Query: 1126 LAEMASL---PEASGSEAPSVPG-------GPNNMPSHVVLPQNQLMMTGPKPGPSPLSA 1175 + ++ P +G++ P+ P P+ P + T P+P + Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TP 2051 Query: 1176 TQGATPQQPPVNSL------PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 T TP P+ + P+ G P P T+ TP +P P QTP P Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTP---TPTPTGTQTPTTTP 2107 Query: 1230 PSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN 1289 +T + ++ +P P + P P PTT Sbjct: 2108 ITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVT 2161 Query: 1290 LTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKT-TPSPGRQN 1348 T P+ TP T + + + + +G +P+ + ++ + T TP+ + Sbjct: 2162 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTP 2218 Query: 1349 SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAV 1408 + P T + T + P ++ T P + P +T +V Sbjct: 2219 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2278 Query: 1409 GGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 + P + + + P V P P+ Sbjct: 2279 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-T 2336 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT-------IKPPGLTDLEVTP-PVV 1520 + + +P + PT+ + P T P T VTP P Sbjct: 2337 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2396 Query: 1521 SGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS 1580 +G + I T ++ + P+ + P + + ++ + P+ + Sbjct: 2397 TGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPT-----T 2450 Query: 1581 RPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMV 1640 P+++++ TP P T T+ PITT T+ PT + + T + V Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507 Query: 1641 SEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPL 1700 + + Q+ T + + G+Q T TT P P Sbjct: 2508 TPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2564 Query: 1701 HIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPV 1760 P + P P + +P T P+ ++ TP P+P T +P P+ Sbjct: 2565 TTPITTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPT--PTPTGTQTPTT---TPI 2614 Query: 1761 QQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKV 1820 + P +P + T P + +TT V+P T + G+ +P++++ Sbjct: 2615 TTTTTVTP---TPTPTGTQTPTTTPIT-TTTTVTPTPTPT-GTQTPTTTPITTTTTVTPT 2669 Query: 1821 -DKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT----APGLMGTEQLS---- 1871 G T T ++ G T TT P GT+ + Sbjct: 2670 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2729 Query: 1872 TELDSKTPTP-PAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLV---PSELI 1927 T + TPTP P T T+ T + P+ G PT+ TT V P+ Sbjct: 2730 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2789 Query: 1928 SAVPTT 1933 + PTT Sbjct: 2790 TQTPTT 2795 Score = 55.1 bits (131), Expect = 7e-07 Identities = 165/906 (18%), Positives = 294/906 (32%), Gaps = 85/906 (9%) Query: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESP---QNPSSSP 1125 P P + +V P+P P TP+ + + + +P Q P+++P Sbjct: 2118 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTP 2176 Query: 1126 LAEMASL---PEASGSEAPSVPG-------GPNNMPSHVVLPQNQLMMTGPKPGPSPLSA 1175 + ++ P +G++ P+ P P+ P + T P+P + Sbjct: 2177 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TP 2235 Query: 1176 TQGATPQQPPVNSL------PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 T TP P+ + P+ G P P T+ TP +P P QTP P Sbjct: 2236 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTP---TPTPTGTQTPTTTP 2291 Query: 1230 PSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN 1289 +T + ++ +P P + P P PTT Sbjct: 2292 ITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVT 2345 Query: 1290 LTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKT-TPSPGRQN 1348 T P+ TP T + + + + +G +P+ + ++ + T TP+ + Sbjct: 2346 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTP 2402 Query: 1349 SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAV 1408 + P T + T + P ++ T P + P +T +V Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2462 Query: 1409 GGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 + P + + + P V P P+ Sbjct: 2463 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-T 2520 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT-------IKPPGLTDLEVTP-PVV 1520 + + +P + PT+ + P T P T VTP P Sbjct: 2521 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2580 Query: 1521 SGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS 1580 +G + I T ++ + P+ + P + + ++ + P+ + Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPT-----T 2634 Query: 1581 RPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMV 1640 P+++++ TP P T T+ PITT T+ PT + + T + V Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2691 Query: 1641 SEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPL 1700 + + Q+ T + + G+Q T TT P P Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2748 Query: 1701 HIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPV 1760 P + P P + +P T P+ ++ TP P+P T +P P+ Sbjct: 2749 TTPITTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPT--PTPTGTQTPTT---TPI 2798 Query: 1761 QQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKV 1820 + P +P + T P + +TT V+P T + G+ +P++++ Sbjct: 2799 TTTTTVTP---TPTPTGTQTPTTTPIT-TTTTVTPTPTPT-GTQTPTTTPITTTTTVTPT 2853 Query: 1821 -DKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT----APGLMGTEQLS---- 1871 G T T ++ G T TT P GT+ + Sbjct: 2854 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2913 Query: 1872 TELDSKTPTP-PAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLV---PSELI 1927 T + TPTP P T T+ T + P+ G PT+ TT V P+ Sbjct: 2914 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2973 Query: 1928 SAVPTT 1933 + PTT Sbjct: 2974 TQTPTT 2979 Score = 55.1 bits (131), Expect = 7e-07 Identities = 165/906 (18%), Positives = 294/906 (32%), Gaps = 85/906 (9%) Query: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESP---QNPSSSP 1125 P P + +V P+P P TP+ + + + +P Q P+++P Sbjct: 2302 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTP 2360 Query: 1126 LAEMASL---PEASGSEAPSVPG-------GPNNMPSHVVLPQNQLMMTGPKPGPSPLSA 1175 + ++ P +G++ P+ P P+ P + T P+P + Sbjct: 2361 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TP 2419 Query: 1176 TQGATPQQPPVNSL------PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 T TP P+ + P+ G P P T+ TP +P P QTP P Sbjct: 2420 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTP---TPTPTGTQTPTTTP 2475 Query: 1230 PSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN 1289 +T + ++ +P P + P P PTT Sbjct: 2476 ITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVT 2529 Query: 1290 LTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKT-TPSPGRQN 1348 T P+ TP T + + + + +G +P+ + ++ + T TP+ + Sbjct: 2530 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTP 2586 Query: 1349 SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAV 1408 + P T + T + P ++ T P + P +T +V Sbjct: 2587 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2646 Query: 1409 GGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 + P + + + P V P P+ Sbjct: 2647 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-T 2704 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT-------IKPPGLTDLEVTP-PVV 1520 + + +P + PT+ + P T P T VTP P Sbjct: 2705 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2764 Query: 1521 SGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS 1580 +G + I T ++ + P+ + P + + ++ + P+ + Sbjct: 2765 TGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPT-----T 2818 Query: 1581 RPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMV 1640 P+++++ TP P T T+ PITT T+ PT + + T + V Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2875 Query: 1641 SEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPL 1700 + + Q+ T + + G+Q T TT P P Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2932 Query: 1701 HIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPV 1760 P + P P + +P T P+ ++ TP P+P T +P P+ Sbjct: 2933 TTPITTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPT--PTPTGTQTPTT---TPI 2982 Query: 1761 QQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKV 1820 + P +P + T P + +TT V+P T + G+ +P++++ Sbjct: 2983 TTTTTVTP---TPTPTGTQTPTTTPIT-TTTTVTPTPTPT-GTQTPTTTPITTTTTVTPT 3037 Query: 1821 -DKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT----APGLMGTEQLS---- 1871 G T T ++ G T TT P GT+ + Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3097 Query: 1872 TELDSKTPTP-PAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLV---PSELI 1927 T + TPTP P T T+ T + P+ G PT+ TT V P+ Sbjct: 3098 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3157 Query: 1928 SAVPTT 1933 + PTT Sbjct: 3158 TQTPTT 3163 Score = 55.1 bits (131), Expect = 7e-07 Identities = 165/906 (18%), Positives = 294/906 (32%), Gaps = 85/906 (9%) Query: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESP---QNPSSSP 1125 P P + +V P+P P TP+ + + + +P Q P+++P Sbjct: 2486 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTP 2544 Query: 1126 LAEMASL---PEASGSEAPSVPG-------GPNNMPSHVVLPQNQLMMTGPKPGPSPLSA 1175 + ++ P +G++ P+ P P+ P + T P+P + Sbjct: 2545 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TP 2603 Query: 1176 TQGATPQQPPVNSL------PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 T TP P+ + P+ G P P T+ TP +P P QTP P Sbjct: 2604 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTP---TPTPTGTQTPTTTP 2659 Query: 1230 PSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN 1289 +T + ++ +P P + P P PTT Sbjct: 2660 ITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVT 2713 Query: 1290 LTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKT-TPSPGRQN 1348 T P+ TP T + + + + +G +P+ + ++ + T TP+ + Sbjct: 2714 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTP 2770 Query: 1349 SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAV 1408 + P T + T + P ++ T P + P +T +V Sbjct: 2771 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2830 Query: 1409 GGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 + P + + + P V P P+ Sbjct: 2831 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-T 2888 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT-------IKPPGLTDLEVTP-PVV 1520 + + +P + PT+ + P T P T VTP P Sbjct: 2889 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2948 Query: 1521 SGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS 1580 +G + I T ++ + P+ + P + + ++ + P+ + Sbjct: 2949 TGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPT-----T 3002 Query: 1581 RPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMV 1640 P+++++ TP P T T+ PITT T+ PT + + T + V Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3059 Query: 1641 SEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPL 1700 + + Q+ T + + G+Q T TT P P Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3116 Query: 1701 HIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPV 1760 P + P P + +P T P+ ++ TP P+P T +P P+ Sbjct: 3117 TTPITTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPT--PTPTGTQTPTT---TPI 3166 Query: 1761 QQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKV 1820 + P +P + T P + +TT V+P T + G+ +P++++ Sbjct: 3167 TTTTTVTP---TPTPTGTQTPTTTPIT-TTTTVTPTPTPT-GTQTPTTTPITTTTTVTPT 3221 Query: 1821 -DKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT----APGLMGTEQLS---- 1871 G T T ++ G T TT P GT+ + Sbjct: 3222 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3281 Query: 1872 TELDSKTPTP-PAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLV---PSELI 1927 T + TPTP P T T+ T + P+ G PT+ TT V P+ Sbjct: 3282 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3341 Query: 1928 SAVPTT 1933 + PTT Sbjct: 3342 TQTPTT 3347 Score = 55.1 bits (131), Expect = 7e-07 Identities = 165/906 (18%), Positives = 294/906 (32%), Gaps = 85/906 (9%) Query: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESP---QNPSSSP 1125 P P + +V P+P P TP+ + + + +P Q P+++P Sbjct: 2670 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTP 2728 Query: 1126 LAEMASL---PEASGSEAPSVPG-------GPNNMPSHVVLPQNQLMMTGPKPGPSPLSA 1175 + ++ P +G++ P+ P P+ P + T P+P + Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TP 2787 Query: 1176 TQGATPQQPPVNSL------PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 T TP P+ + P+ G P P T+ TP +P P QTP P Sbjct: 2788 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTP---TPTPTGTQTPTTTP 2843 Query: 1230 PSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN 1289 +T + ++ +P P + P P PTT Sbjct: 2844 ITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVT 2897 Query: 1290 LTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKT-TPSPGRQN 1348 T P+ TP T + + + + +G +P+ + ++ + T TP+ + Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTP 2954 Query: 1349 SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAV 1408 + P T + T + P ++ T P + P +T +V Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3014 Query: 1409 GGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 + P + + + P V P P+ Sbjct: 3015 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-T 3072 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT-------IKPPGLTDLEVTP-PVV 1520 + + +P + PT+ + P T P T VTP P Sbjct: 3073 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3132 Query: 1521 SGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS 1580 +G + I T ++ + P+ + P + + ++ + P+ + Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPT-----T 3186 Query: 1581 RPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMV 1640 P+++++ TP P T T+ PITT T+ PT + + T + V Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3243 Query: 1641 SEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPL 1700 + + Q+ T + + G+Q T TT P P Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3300 Query: 1701 HIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPV 1760 P + P P + +P T P+ ++ TP P+P T +P P+ Sbjct: 3301 TTPITTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPT--PTPTGTQTPTT---TPI 3350 Query: 1761 QQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKV 1820 + P +P + T P + +TT V+P T + G+ +P++++ Sbjct: 3351 TTTTTVTP---TPTPTGTQTPTTTPIT-TTTTVTPTPTPT-GTQTPTTTPITTTTTVTPT 3405 Query: 1821 -DKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT----APGLMGTEQLS---- 1871 G T T ++ G T TT P GT+ + Sbjct: 3406 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3465 Query: 1872 TELDSKTPTP-PAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLV---PSELI 1927 T + TPTP P T T+ T + P+ G PT+ TT V P+ Sbjct: 3466 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3525 Query: 1928 SAVPTT 1933 + PTT Sbjct: 3526 TQTPTT 3531 Score = 55.1 bits (131), Expect = 7e-07 Identities = 165/906 (18%), Positives = 294/906 (32%), Gaps = 85/906 (9%) Query: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESP---QNPSSSP 1125 P P + +V P+P P TP+ + + + +P Q P+++P Sbjct: 2854 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTP 2912 Query: 1126 LAEMASL---PEASGSEAPSVPG-------GPNNMPSHVVLPQNQLMMTGPKPGPSPLSA 1175 + ++ P +G++ P+ P P+ P + T P+P + Sbjct: 2913 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TP 2971 Query: 1176 TQGATPQQPPVNSL------PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 T TP P+ + P+ G P P T+ TP +P P QTP P Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTP---TPTPTGTQTPTTTP 3027 Query: 1230 PSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN 1289 +T + ++ +P P + P P PTT Sbjct: 3028 ITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVT 3081 Query: 1290 LTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKT-TPSPGRQN 1348 T P+ TP T + + + + +G +P+ + ++ + T TP+ + Sbjct: 3082 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTP 3138 Query: 1349 SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAV 1408 + P T + T + P ++ T P + P +T +V Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3198 Query: 1409 GGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 + P + + + P V P P+ Sbjct: 3199 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-T 3256 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT-------IKPPGLTDLEVTP-PVV 1520 + + +P + PT+ + P T P T VTP P Sbjct: 3257 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3316 Query: 1521 SGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS 1580 +G + I T ++ + P+ + P + + ++ + P+ + Sbjct: 3317 TGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPT-----T 3370 Query: 1581 RPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMV 1640 P+++++ TP P T T+ PITT T+ PT + + T + V Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3427 Query: 1641 SEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPL 1700 + + Q+ T + + G+Q T TT P P Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3484 Query: 1701 HIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPV 1760 P + P P + +P T P+ ++ TP P+P T +P P+ Sbjct: 3485 TTPITTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPT--PTPTGTQTPTT---TPI 3534 Query: 1761 QQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKV 1820 + P +P + T P + +TT V+P T + G+ +P++++ Sbjct: 3535 TTTTTVTP---TPTPTGTQTPTTTPIT-TTTTVTPTPTPT-GTQTPTTTPITTTTTVTPT 3589 Query: 1821 -DKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT----APGLMGTEQLS---- 1871 G T T ++ G T TT P GT+ + Sbjct: 3590 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3649 Query: 1872 TELDSKTPTP-PAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLV---PSELI 1927 T + TPTP P T T+ T + P+ G PT+ TT V P+ Sbjct: 3650 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3709 Query: 1928 SAVPTT 1933 + PTT Sbjct: 3710 TQTPTT 3715 Score = 55.1 bits (131), Expect = 7e-07 Identities = 165/906 (18%), Positives = 294/906 (32%), Gaps = 85/906 (9%) Query: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESP---QNPSSSP 1125 P P + +V P+P P TP+ + + + +P Q P+++P Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTP 3096 Query: 1126 LAEMASL---PEASGSEAPSVPG-------GPNNMPSHVVLPQNQLMMTGPKPGPSPLSA 1175 + ++ P +G++ P+ P P+ P + T P+P + Sbjct: 3097 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TP 3155 Query: 1176 TQGATPQQPPVNSL------PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 T TP P+ + P+ G P P T+ TP +P P QTP P Sbjct: 3156 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTP---TPTPTGTQTPTTTP 3211 Query: 1230 PSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN 1289 +T + ++ +P P + P P PTT Sbjct: 3212 ITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVT 3265 Query: 1290 LTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKT-TPSPGRQN 1348 T P+ TP T + + + + +G +P+ + ++ + T TP+ + Sbjct: 3266 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTP 3322 Query: 1349 SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAV 1408 + P T + T + P ++ T P + P +T +V Sbjct: 3323 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3382 Query: 1409 GGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 + P + + + P V P P+ Sbjct: 3383 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-T 3440 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT-------IKPPGLTDLEVTP-PVV 1520 + + +P + PT+ + P T P T VTP P Sbjct: 3441 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3500 Query: 1521 SGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS 1580 +G + I T ++ + P+ + P + + ++ + P+ + Sbjct: 3501 TGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPT-----T 3554 Query: 1581 RPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMV 1640 P+++++ TP P T T+ PITT T+ PT + + T + V Sbjct: 3555 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3611 Query: 1641 SEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPL 1700 + + Q+ T + + G+Q T TT P P Sbjct: 3612 TPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3668 Query: 1701 HIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPV 1760 P + P P + +P T P+ ++ TP P+P T +P P+ Sbjct: 3669 TTPITTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPT--PTPTGTQTPTT---TPI 3718 Query: 1761 QQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKV 1820 + P +P + T P + +TT V+P T + G+ +P++++ Sbjct: 3719 TTTTTVTP---TPTPTGTQTPTTTPIT-TTTTVTPTPTPT-GTQTPTTTPITTTTTVTPT 3773 Query: 1821 -DKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT----APGLMGTEQLS---- 1871 G T T ++ G T TT P GT+ + Sbjct: 3774 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3833 Query: 1872 TELDSKTPTP-PAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLV---PSELI 1927 T + TPTP P T T+ T + P+ G PT+ TT V P+ Sbjct: 3834 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3893 Query: 1928 SAVPTT 1933 + PTT Sbjct: 3894 TQTPTT 3899 Score = 45.4 bits (106), Expect = 6e-04 Identities = 114/606 (18%), Positives = 198/606 (32%), Gaps = 64/606 (10%) Query: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESP---QNPSSSP 1125 P P + +V P+P P TP+ + + + +P Q P+++P Sbjct: 3728 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTP 3786 Query: 1126 LAEMASL---PEASGSEAPSVPG-------GPNNMPSHVVLPQNQLMMTGPKPGPSPLSA 1175 + ++ P +G++ P+ P P+ P + T P+P + Sbjct: 3787 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TP 3845 Query: 1176 TQGATPQQPPVNSL------PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 T TP P+ + P+ G P P T+ TP +P P QTP P Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTP---TPTPTGTQTPTTTP 3901 Query: 1230 PSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN 1289 +T + ++ +P P + P P PTT Sbjct: 3902 ITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVT 3955 Query: 1290 LTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKT-TPSPGRQN 1348 T P+ TP T + + + + +G +P+ + ++ + T TP+ + Sbjct: 3956 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTP 4012 Query: 1349 SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAV 1408 + P T + T + P ++ T P + P +T +V Sbjct: 4013 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4072 Query: 1409 GGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 + P + + + P V P P+ Sbjct: 4073 P-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-T 4130 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT-------IKPPGLTDLEVTP-PVV 1520 + + +P + PT+ + P T P T VTP P Sbjct: 4131 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4190 Query: 1521 SGEDLKKASVIPT--LQDLSSSKEP----------SNSLNLPHSNELCSSLVHPELSEVS 1568 +G + T + +L++S P S S L S L S+L P E++ Sbjct: 4191 TGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTL--PPAIEMT 4248 Query: 1569 SNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPI--TTSANTSAALPTHLQSALMS 1626 S PS P + P ++S T PP T P TT+ ++SA P+ +Q+ S Sbjct: 4249 STAPPSTP---TAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTS 4305 Query: 1627 TVVTMP 1632 P Sbjct: 4306 AWTPTP 4311 Score = 45.1 bits (105), Expect = 7e-04 Identities = 148/805 (18%), Positives = 255/805 (31%), Gaps = 97/805 (12%) Query: 1154 VVLPQNQLMMTGPKPGP---SPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPK 1210 V P T P P +P++ T TP P + + P T+ Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT--------TTPITTTTTV 1930 Query: 1211 TPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGF 1270 TP +P P QTP P +T + ++ +P P + P P Sbjct: 1931 TP---TPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT----- 1981 Query: 1271 DQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSR 1330 PTT T P+ TP T + + + + +G +P+ + Sbjct: 1982 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTP 2038 Query: 1331 RSSPGSSRKT-TPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGS 1389 ++ + T TP+ + + P T + T + P ++ T P + Sbjct: 2039 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2098 Query: 1390 FPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEV 1449 P +T +V P + Q + P Sbjct: 2099 GTQTPTTTPITTTTTVTPT-------------PTPTGTQTPTT-----------TPITTT 2134 Query: 1450 KMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT----- 1504 V P P+ + + +P + PT+ + P T Sbjct: 2135 TTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2193 Query: 1505 --IKPPGLTDLEVTP-PVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVH 1561 P T VTP P +G + I T ++ + P+ + P + + ++ Sbjct: 2194 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTV 2252 Query: 1562 PELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQ 1621 + P+ + P+++++ TP P T T+ PITT T+ PT Sbjct: 2253 TPTPTPTGTQTPT-----TTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTP 2304 Query: 1622 SALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAA 1681 + + T + V + + Q+ T + + G+Q T Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPI 2361 Query: 1682 PLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPV 1741 TT P P P + P P + +P T P+ ++ TP Sbjct: 2362 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPT 2416 Query: 1742 QLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSP 1801 P+P T +P P+ + P +P + T P + +TT V+P T + Sbjct: 2417 --PTPTGTQTPTT---TPITTTTTVTP---TPTPTGTQTPTTTPIT-TTTTVTPTPTPT- 2466 Query: 1802 GSSGNRRSPVSSSKGKGKV-DKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT 1860 G+ +P++++ G T T ++ G T TT Sbjct: 2467 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2526 Query: 1861 ----APGLMGTEQLS----TELDSKTPTP-PAPTLLKMTSSPVGPGTASAGPSLPGGALP 1911 P GT+ + T + TPTP P T T+ T + P+ G P Sbjct: 2527 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2586 Query: 1912 TSVRSIVTTLV---PSELISAVPTT 1933 T+ TT V P+ + PTT Sbjct: 2587 TTTPITTTTTVTPTPTPTGTQTPTT 2611 Score = 40.4 bits (93), Expect = 0.018 Identities = 56/242 (23%), Positives = 73/242 (30%), Gaps = 28/242 (11%) Query: 309 PTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQT 368 PT P PP P+ PP T T + P P P + T T Sbjct: 1402 PTTTPSPP-----PTSTTTLPP------TTTPSPPTTTTTTPPPTTTP---SPPITTTTT 1447 Query: 369 PSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSP 428 P PP S S T P + T P + P T P T P Sbjct: 1448 P----PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPP 1503 Query: 429 ASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPN 488 ++P + PAS+ T+ T P P P P ++ P +PP Sbjct: 1504 TTTPIT----PPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1559 Query: 489 FMVMQQQPP---NQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSG 545 PP P + P PP + P P+TT TTP + Sbjct: 1560 --TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSP-PTTTTTTPPPTT 1616 Query: 546 AP 547 P Sbjct: 1617 TP 1618 Score = 39.3 bits (90), Expect = 0.040 Identities = 59/250 (23%), Positives = 81/250 (32%), Gaps = 46/250 (18%) Query: 304 PQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSL 363 P T T P P P+G Q P T T P P P Q + Sbjct: 4085 PITTTTTVTPTPT-----PTGT-QTPTTTPITTTTTVT------PTPTPTGTQTPTTTPI 4132 Query: 364 ATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHL 423 T T + P P P G+Q + T P + P+ PT Q P Sbjct: 4133 TTTTTVT--PTPTPTGTQTPT---------------TTPITTTTTVTPTPTPTGTQTPTT 4175 Query: 424 T------NKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRN 477 T +P +P+ Q G P + T + PP+++ PQ + SSP Sbjct: 4176 TPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESS-TPQ-TSRSTSSPLTE 4233 Query: 478 PMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTT 537 +PP + PP+ P + GG PP + T Sbjct: 4234 STTLLSTLPPAIEMTSTAPPST-PTAPTTTSGGHTLSPPPSTTTSPPG--------TPTR 4284 Query: 538 ATTPGNSGAP 547 TT G+S AP Sbjct: 4285 GTTTGSSSAP 4294 Score = 38.1 bits (87), Expect = 0.090 Identities = 53/246 (21%), Positives = 78/246 (31%), Gaps = 27/246 (10%) Query: 309 PTQVPVPPGWNQL--PSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATV 366 PT P PP + P+ PP T P P P+ T Sbjct: 1496 PTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1555 Query: 367 QTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNK 426 P+ P P P + + T P + P + + P+ P+P P T Sbjct: 1556 LPPTTTPSPPP--TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSP---PTTTTT 1610 Query: 427 SPA-----SSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQ 481 +P S P++ P S+ T+ T P P P P ++ +P + Sbjct: 1611 TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPIT 1670 Query: 482 QGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTP 541 P PP P S + P PP + +P P TT TTP Sbjct: 1671 TTTTP---------PPTTTPSS---PITTTPS--PPTTTMTTPSPTTTPSS-PITTTTTP 1715 Query: 542 GNSGAP 547 ++ P Sbjct: 1716 SSTTTP 1721 Score = 36.2 bits (82), Expect = 0.34 Identities = 37/158 (23%), Positives = 48/158 (30%), Gaps = 8/158 (5%) Query: 309 PTQVPVPPGWNQL--PSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATV 366 PT P PP + P+ PP T P P + P T Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673 Query: 367 QTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMK-SLQGGPSRVPTPLQQPH-LT 424 P P P + + T M+ P T P + PS TP P +T Sbjct: 1674 TPPPTTTPSSPITTTPSPPTTT----MTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMT 1729 Query: 425 NKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNP 462 SP ++PS PT + P PP P Sbjct: 1730 TPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP 1767 Score = 32.7 bits (73), Expect = 3.8 Identities = 56/243 (23%), Positives = 85/243 (34%), Gaps = 31/243 (12%) Query: 997 PPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP 1056 PP P +L PP S PQ+ + L+ P ++ + + P Sbjct: 4197 PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTL-PPAIEM---TSTAP 4252 Query: 1057 PRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQE 1116 P P P + SG + S P +P + T GS+S Sbjct: 4253 PSTPTAPTT------TSGGHTLSPPPSTTTSPPGTPTR-------GTTTGSSS------- 4292 Query: 1117 SPQNPSSSPLAEMASLPEASGSEAPSV--PGGPNNMPSHVVLPQNQLMMTGPKPGPSPLS 1174 +P + A P + PS+ G PS V++ L T PG + Sbjct: 4293 APTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLI-CCVLNDTYYAPGEEVYN 4351 Query: 1175 ATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYP-QTPNNRPPSTE 1233 T G T + S F N + P+ S TP++++P P P TP+ P T+ Sbjct: 4352 GTYGDTCY---FVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTK 4408 Query: 1234 PSE 1236 P E Sbjct: 4409 PPE 4411 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 92.8 bits (229), Expect = 3e-18 Identities = 231/1161 (19%), Positives = 403/1161 (34%), Gaps = 153/1161 (13%) Query: 958 NSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPP----QPPQQQPQPQLPQQQ 1013 +S P PE + P S+ PL MP M+ + P + P Q Sbjct: 195 SSSPTTPESTTIPKSTNSEG--STPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQ 252 Query: 1014 QPPPP----------SQPQSQQQQQQQQQMMMMLMMQQD-------PKSVRLPVSQNVHP 1056 P S P + + +ML++ + P + +PV + Sbjct: 253 ASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEA 312 Query: 1057 PRGPLNPDSQRMPMQQ--SGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVY 1114 P + +P GS P+ + PAS P + + + TP+ +++ Sbjct: 313 SSSPTTAEGTSIPTSTYTEGSTPLTST---PASTMPVATSEMSTLSI-TPVDTSTLVTTS 368 Query: 1115 QESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMP-SHVVLPQNQLMMTGPKPGPSPL 1173 E P+++ M + + GS + NMP S +++ ++ T P S Sbjct: 369 TEPSSLPTTAEATSMLTSTLSEGSTPLT------NMPVSTILVASSEASTTSTIPVDSKT 422 Query: 1174 SATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRP--KTPNRASPRPYYPQTP-NNRPP 1230 T + P + +S P+ + TS P TP +S TP +++ Sbjct: 423 FVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQ 482 Query: 1231 STEPSEISLSPERLNA-SIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSN 1289 T +E S SP S+ P + + PL ++ +T+ S Sbjct: 483 VTTSTEASSSPPTAEVNSMPTSTPSEGSTPLT------------SMSVSTMPVASSEAST 530 Query: 1290 LTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNS 1349 L+ P + +TP V S + S+S T + + S GS+ T + Sbjct: 531 LSTTPVDTSTP--------VTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLV 582 Query: 1350 KAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVG 1409 + + + S T A V S T +P S + G + +VS V Sbjct: 583 VSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVA 642 Query: 1410 GVVEDNKESLNVPQDSDCQNS-QSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 + V ++ S ++ E ++P E + P + Sbjct: 643 SSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTS----TYTEGSTPLTSMPVNTT 698 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKA 1528 + S E + +P P + S +S P T E + P+ S K Sbjct: 699 LVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTL 758 Query: 1529 SVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSI 1588 LS++ +++ + CS S S + P + S PVS + + Sbjct: 759 LTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPV 818 Query: 1589 STPLPPNQITVFVTSN-PITTSANTSA--------ALPTHLQSALMSTVVTMPNAGSKVM 1639 ++P T V SN P+TTS S+ ++PT S + + +MP S + Sbjct: 819 TSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMP--VSTTL 876 Query: 1640 VSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGP 1699 V+ + S TPV + + ++P T+ MP S G Sbjct: 877 VATSAISTLSTTPVDTSTPV-------------TNSTEARSSPTTSEGTSMPTSTPGEGS 923 Query: 1700 LHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRAT-----------PVQLPS--- 1745 + ++ S+ PV + + A + T P+ S+ AT P PS Sbjct: 924 TPL-TSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGT 982 Query: 1746 PPCTSSPV---VPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPG 1802 P TS+PV + ++ + D +P ++ + P+++ T+M P T S G Sbjct: 983 TPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSM--PTSTPSEG 1040 Query: 1803 SSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGE-------TEGQ 1855 S+ R PVS++ VT + ADG +EG Sbjct: 1041 STPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGS 1100 Query: 1856 GLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGP-SLPGGALPTSV 1914 T+ P + T + + S T P T + +T+S AS+ P + G ++PTS Sbjct: 1101 TPLTSVP--VSTRLVVSSEASTLSTTPVDTSIPVTTST----EASSSPTTAEGTSIPTSP 1154 Query: 1915 RSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKE 1974 S TT + S +S S +++ + SK Sbjct: 1155 PSEGTTPLASMPVSTTLVVSSEANTLSTTPVD-------------------------SKT 1189 Query: 1975 TSTTALQASVARPELEVNAAIVS--GQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVEN 2032 T+ +AS P EV + S G+ S P + P + +E T+++ V+ Sbjct: 1190 QVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTP---VASSEASTLSTSPVDT 1246 Query: 2033 GHRKRSSRPASASSSTKDITS 2053 +S S+S +T + TS Sbjct: 1247 STPVTTSAETSSSPTTAEGTS 1267 Score = 92.4 bits (228), Expect = 4e-18 Identities = 233/1092 (21%), Positives = 391/1092 (35%), Gaps = 181/1092 (16%) Query: 1075 SVPVMVSLQGPASVPPSPDKQRMPMPVN----TPLGSNSRKMVYQESPQNPSSSPLAEMA 1130 S P+ S Q +S P +P+ +P N TPL S + S + + Sbjct: 185 STPLTTSTQASSS-PTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEI 243 Query: 1131 SLP---EASGSEAPSVPGGP---NNMPSHVVLPQNQL---MMTGPKPGPSPLSATQGATP 1181 S P A S +P+ GP N+ PS P ++ +M S LS T AT Sbjct: 244 STPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATN 303 Query: 1182 QQPPVNSLPSSHGHHFPNVAAPTQT-SRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLS 1240 ++ SS + PT T + TP ++P P ++E S +S++ Sbjct: 304 IPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVA------TSEMSTLSIT 357 Query: 1241 PERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATP 1300 P + + P++L +A S LT S +TP Sbjct: 358 PVDTSTLVT-----------------------TSTEPSSLPTTAEATSMLTSTLSEGSTP 394 Query: 1301 QTHKLDSVVVNSGKQSNSGAT------KRASPSNSRRSSPGSSRKT-----TPSPGRQ-- 1347 T+ S ++ + ++++ +T + ++ SSP ++ T TPS G Sbjct: 395 LTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPL 454 Query: 1348 NSKAPKLTLASQTNAALLQN--VELPRNVLVSPTPLANPP------VPGSFPNNSGLNPQ 1399 S T + + A+ L V+ V S ++PP +P S P+ Sbjct: 455 TSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLT 514 Query: 1400 NSTVSVAAVGGVVEDNKE------SLNVPQDSDCQNSQSRKEQVNIELKAVPAQ------ 1447 + +VS V S V S+ +S + E +I + P++ Sbjct: 515 SMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPT-STPSEGSTPLT 573 Query: 1448 ----EVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNV 1503 ++VV + S P+D N + + S S + + P Sbjct: 574 NMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEAS-----------SSSTTAEGTSMPTS 622 Query: 1504 TIKPPG--LTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVH 1561 T G +T + V+ +V+ + S P SN+ + SS Sbjct: 623 TYSERGTTITSMSVSTTLVASSEASTLSTTPV---------DSNTPVTTSTEATSSSTTA 673 Query: 1562 PELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFV-TSNPITTSANTSAALPTHL 1620 S +S P+ S PV+++ +++ T V TS P+TTS S++ PT Sbjct: 674 EGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSS-PTTA 732 Query: 1621 QSALMSTVVTMPNAGSKVMVSEGQSAA---QSNARPQFITPVFINSSSIIQVMKGSQPST 1677 A M T + P+ GS + S S S A TP+ ++ P+T Sbjct: 733 DGASMPT--STPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTT 790 Query: 1678 -----IPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNA-------LSSSPAPN 1725 +P + + S L+ + P+ P+ S+ PV N+ +SSSP P Sbjct: 791 TEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPA 850 Query: 1726 IQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNP---DEASPQVNTSADQN 1782 T P S P TS PV + + L+ D ++P N++ ++ Sbjct: 851 EGTSMPTSTYSEGRT------PLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARS 904 Query: 1783 TLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKG 1842 + +S+ T+M P T GS+ P S++ + VT S E Sbjct: 905 SPTTSEGTSM--PTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEAT 962 Query: 1843 EEQYGADGETEGQGLDTTAPGLMGTEQLSTELD------------SKTPTPPAPTLLKMT 1890 A EG + T+ P T ST + S TP L T Sbjct: 963 SSPTTA----EGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTST 1018 Query: 1891 SSPVGPGTASAGPSLPG-----GALPTSVRSIVTTLVPSELISAVPTTKSN-------HG 1938 + P TA G S+P G+ P + + TT+V S S + TT ++ + Sbjct: 1019 EASSPPPTAE-GTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYS 1077 Query: 1939 GIASESLAGGLVEEKVGSHPE---LLPSIAPSQNL-VSKETS-------------TTALQ 1981 +S S ++ E L S+ S L VS E S TT+ + Sbjct: 1078 QASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTE 1137 Query: 1982 ASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSRP 2041 AS + P +I + SE + + +E T+++ V++ + +S Sbjct: 1138 AS-SSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE 1196 Query: 2042 ASASSSTKDITS 2053 AS+ T ++TS Sbjct: 1197 ASSPPPTAEVTS 1208 Score = 91.7 bits (226), Expect = 7e-18 Identities = 213/1067 (19%), Positives = 374/1067 (35%), Gaps = 107/1067 (10%) Query: 995 APPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNV 1054 +PPP P + P P S + + P PV+ Sbjct: 1022 SPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTL----STTPADTSTPVTTYS 1077 Query: 1055 HPPRGPLNPDSQRMPMQ--QSGSVPV--------MVSLQGPASVPPSPDKQRMPMPVNTP 1104 D MP GS P+ +V +++ +P +P+ +T Sbjct: 1078 QASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTE 1137 Query: 1105 LGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMT 1164 S+ P +P S +AS+P S V N + + V + Q+ + Sbjct: 1138 ASSSPTTAEGTSIPTSPPSEGTTPLASMPV---STTLVVSSEANTLSTTPVDSKTQVATS 1194 Query: 1165 GPKPGPSPLSATQGATPQQPPVNSLP--SSHGHHFPNVAAPTQTSRPKTPNRASPRPYYP 1222 P P + P S P S H P ++ T + ++P Sbjct: 1195 TEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSA 1254 Query: 1223 QTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPN--LNRGFDQQG------ 1274 +T ++ P + E + + S +++ P + P + L D +G Sbjct: 1255 ETSSS-PTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSN 1313 Query: 1275 ------------LNPTTLKAIGQAP-SNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGAT 1321 PT+ + G+ P +++ +N + A+ L + V++ + Sbjct: 1314 EVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTE 1373 Query: 1322 KRASPSNSRRSS-PGS--SRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLV-- 1376 +SP+ S +S P S S TTP S P ++ + T +A + P Sbjct: 1374 ACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEA 1433 Query: 1377 --SPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRK 1434 SPT +P S P+ ++ VS V + V +S S + Sbjct: 1434 TSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTA-- 1491 Query: 1435 EQVNIELKAVPAQEVKMVVP---EDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAP-TS 1490 + PA+ + + E + P + S E N +PA+ P T+ Sbjct: 1492 ----VSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTT 1547 Query: 1491 LSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLP 1550 SQ + + T TP ++ + V+ + + S+ + + Sbjct: 1548 YSQASSSPTTADGTSMQTSTYSEGSTP--LTSLPVSTMLVVSSEANTLSTTPIDSKTQVT 1605 Query: 1551 HSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSN-PITTS 1609 S E SS S S + P + S PVS++ +++P T V SN P+ TS Sbjct: 1606 ASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITS 1665 Query: 1610 ANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQV 1669 S++ PT + M T ++ + S+A T NS+ + Sbjct: 1666 TEVSSS-PTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPV--- 1721 Query: 1670 MKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTG 1729 + + ++P T+ MP S G + +I S+ PV + S+ A I T Sbjct: 1722 ---TTSTEARSSPTTSEGTSMPNSTPSEGTTPLT-SIPVSTTPVLSSEASTLSATPIDTS 1777 Query: 1730 RPLVLSSRATP-------VQLPSP-------PCTSSPVVPSHPPVQQVKELNP---DEAS 1772 P+ S+ AT +P+ P TS+PV + + L+ D S Sbjct: 1778 TPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNS 1837 Query: 1773 PQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKAC 1832 P V ++A ++ ++ T++ + T S GS+ PVS++ Sbjct: 1838 PVVTSTAVSSSPTPAEGTSIATS--TPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTS 1895 Query: 1833 KKVTGSLEKGEEQYGADGET-------EGQGLDTTAPGLMGTEQLSTELDSKTPT----- 1880 VT + ADG + EG+ T+ P + T S+E+++ + T Sbjct: 1896 TPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIP-VSTTTVASSEINTLSTTLADTR 1954 Query: 1881 PPAPTLLKMTSSPV-GPGTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGG 1939 P T + +SSP GT+ P+ G+ P + + TTLV S S + TT + Sbjct: 1955 TPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTST 2014 Query: 1940 IASESLAGGLVEEKVGSHPELLPSIAPSQN---LVSKETSTTALQAS 1983 A+ S G G + + PS+ L STT + +S Sbjct: 2015 PATTSTEGSSSPTTAGG--TSIQTSTPSERTTPLAGMPVSTTLVVSS 2059 Score = 85.5 bits (210), Expect = 5e-16 Identities = 218/983 (22%), Positives = 359/983 (36%), Gaps = 129/983 (13%) Query: 1075 SVPVMVSLQGPASVPPSPDKQRM----PMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMA 1130 S PV S + +S P + + M P +TPL S + S + + S A Sbjct: 2720 STPVTTSAEASSS-PTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDT 2778 Query: 1131 SLPEASGSEAPSVP------GGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQP 1184 S+P + +EA S P P + PS P +T +P+++++ T Sbjct: 2779 SIPVTTSTEASSSPTTAEVTSMPTSTPSETSTP-----LTSMPVNHTPVASSEAGTLSTT 2833 Query: 1185 PVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERL 1244 PV++ + T T +P A T + +S +P Sbjct: 2834 PVDT----------STPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVAS 2883 Query: 1245 N-ASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTH 1303 + AS P +IP+ + +PTT + S PS +TP T Sbjct: 2884 SEASTLSTTPVDTSIPVTTST-------EGSSSPTTAEGTSMPIST----PSEVSTPLTS 2932 Query: 1304 KLDSVVVNSGKQSN----------SGATKRASPSNSRRSSPGSS-------RKTTPSPGR 1346 L S V +G +++ + T A S+S ++ G+S + TP Sbjct: 2933 ILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSM 2992 Query: 1347 QNSKAP----KLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNST 1402 S P + + S+T A V SPT +P S P + G P S Sbjct: 2993 SVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTP-SEGSTPLTS- 3050 Query: 1403 VSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVV---PEDQSK 1459 + V+ + + P DS+ S + PA+ M + E + Sbjct: 3051 IPVSTTPVAIPEASTLSTTPVDSNSPVVTS----TEVSSSPTPAEGTSMPISTYSEGSTP 3106 Query: 1460 KDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPV 1519 G P + S + +P P + S +S + P T E + P Sbjct: 3107 LTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTP- 3165 Query: 1520 VSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVM 1579 ++ + V+ + S+ S + S E SS S +S + + P+ Sbjct: 3166 LTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLT 3225 Query: 1580 SRPVSSSSISTPLPPNQITVFVTSN-PITTSANTSAALPTHLQSALMSTVVTMPNAGSKV 1638 S PVS++ +++ T V SN P+TTS S++ PT + M T + P+ GS Sbjct: 3226 SVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPT-AEGTSMPT--STPSEGSTP 3282 Query: 1639 MVS---EGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVA 1695 + S + A S TP + + V SQ S+ P P+ + MP S Sbjct: 3283 LTSMPVSTTTVASSETSTLSTTP----ADTSTPVTTYSQASSSP--PIADGTS-MPTSTY 3335 Query: 1696 VVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVP 1755 G + N+ FS+ PV + S+ + T P+ S+ A+ SP +P Sbjct: 3336 SEGSTPL-TNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEAS----LSPTTAEGTSIP 3390 Query: 1756 SHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMV--SPLLTNSPGSSGNRRSPVSS 1813 + P + L S S++ NTL STT V + L+T S +S SP + Sbjct: 3391 TSSPSEGTTPLASMPVSTTPVVSSEVNTL----STTPVDSNTLVTTSTEASS---SPTIA 3443 Query: 1814 SKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTE 1873 G L T + + L +E L TT ST Sbjct: 3444 E---------GTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTT------PVDTSTP 3488 Query: 1874 LDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTT 1933 + + +PT +PT ++TS P T++AG G+ P + + TT V S S + TT Sbjct: 3489 VTTSSPTNSSPTTAEVTSMP----TSTAGE----GSTPLTNMPVSTTPVASSEASTLSTT 3540 Query: 1934 --KSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQ--NLVSKETSTTALQASV-ARPE 1988 SN +S + +V + PS S ++ T T+ +AS + P Sbjct: 3541 PVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPS 3600 Query: 1989 LE----VNAAIVSGQSSEPKEIV 2007 ++ V + S + P E++ Sbjct: 3601 VDRSTPVTTSTQSNSTPTPPEVI 3623 Score = 85.1 bits (209), Expect = 6e-16 Identities = 219/1039 (21%), Positives = 372/1039 (35%), Gaps = 156/1039 (15%) Query: 1085 PASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPS----------SSPLAEMASLPE 1134 P S P MPV+T L +S +P + S SS AE S+P Sbjct: 3155 PTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPT 3214 Query: 1135 ASGSEA----PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLP 1190 ++ SE SVP +N P V + ++ T P +PL+ + A+ +S P Sbjct: 3215 STPSEGMTPLTSVP--VSNTP--VASSEASILSTTPVDSNTPLTTSTEAS------SSPP 3264 Query: 1191 SSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAG 1250 ++ G P + P++ S P T S S+E S +S +P + + Sbjct: 3265 TAEGTSMPT-STPSEGSTPLTSMPVS---------TTTVASSETSTLSTTPADTSTPVTT 3314 Query: 1251 LFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAP------SNLTMNPSNFATPQTHK 1304 + P+ ++ +G P T + P S L+ P + +TP T Sbjct: 3315 YSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTS 3374 Query: 1305 LDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAAL 1364 ++ + + + S T SSP S TTP S P ++S+ N Sbjct: 3375 TEASLSPTTAEGTSIPT----------SSP--SEGTTPLASMPVSTTP--VVSSEVNTLS 3420 Query: 1365 LQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQD 1424 V+ V S ++P + G + ST S + L++ Sbjct: 3421 TTPVDSNTLVTTSTEASSSPTIA------EGTSLPTSTTS---------EGSTPLSIMPL 3465 Query: 1425 SDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAM 1484 S + S ++ P D S S N P+ E ++ + Sbjct: 3466 STTPVASSEASTLS-------------TTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTA 3512 Query: 1485 REAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQ----DLSSS 1540 E T L+ + S P + + L+ V + +S TLQ +S+ Sbjct: 3513 GEGSTPLTNM-PVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTP 3571 Query: 1541 KEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITV- 1599 E S+SL + S + SE S+ PS+ S+ S STP PP IT+ Sbjct: 3572 SEGSSSLTT-----MLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLP 3626 Query: 1600 FVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFIT-P 1658 T + ++T T + + T T+P S +++ Q + S P+ T P Sbjct: 3627 MSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQ-VSSSPVTPEGTTMP 3685 Query: 1659 VFINSSSIIQVMKGSQPST---IPAAPLTTNSG--LMPPSVAVVGPLHIPQNIKFSSAPV 1713 ++ S +GS P T + +T++ G L PSV P+ SSA + Sbjct: 3686 IWTPS-------EGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATL 3738 Query: 1714 PPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASP 1773 +S S I T +L S + P +S+P +PS + + +SP Sbjct: 3739 DSTTMSVSMPMEISTLGTTILVSTTPVTRFPE---SSTPSIPSVYTSMSMTTASEGSSSP 3795 Query: 1774 ---------QVNTSADQNTLPSSQSTTMVSPLLTNSPGSS-------GNRRSPVSSSKGK 1817 ++T+++++TL +T ++SP+ SP + G+ +P+ +S Sbjct: 3796 TTLEGTTTMPMSTTSERSTL---LTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKA 3852 Query: 1818 GKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETE--GQGLDTTAPGLMGTEQLSTELD 1875 G ++ + S T G + +T P T + Sbjct: 3853 GSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDT 3912 Query: 1876 SKTPTPPAPTLLKMTSSPVG--PGTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTT 1933 + TPT P T + ++ G PGT PS P + V T V + +I+ +T Sbjct: 3913 ASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVIT---ST 3969 Query: 1934 KSNHGGIASESLAGGLVEEKVGSHPELLP---------SIAPSQNLVSKETSTTALQASV 1984 + N +S S K + P + S APS + TT+ Sbjct: 3970 ELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLS 4029 Query: 1985 ARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSRPASA 2044 A + ++ ++ P +S P S T PT S+ P ++ Sbjct: 4030 ATSTPHTSTSV----TTRPVTPSSESSRPSTITSHTIPPTFPP-------AHSSTPPTTS 4078 Query: 2045 SSSTKDITSAVQSKRRKSK 2063 +SST AV + ++K Sbjct: 4079 ASSTTVNPEAVTTMTTRTK 4097 Score = 84.7 bits (208), Expect = 8e-16 Identities = 206/951 (21%), Positives = 358/951 (37%), Gaps = 113/951 (11%) Query: 1063 PDSQRMPMQQSGSVPVM---VSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQ 1119 P + P++ S+PV V+ +++ +P P+ +T + S+ Sbjct: 1450 PSEGKTPLK---SIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAI 1506 Query: 1120 NPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGA 1179 + S + S+P ++ + A S + P+ P P + ++ Q + Sbjct: 1507 STPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTS 1566 Query: 1180 TPQQ--PPVNSLP-------SSHGHHFPN--------VAAPTQTSRPKTPNRASPRPYYP 1222 T + P+ SLP SS + V A T+ S T +S Sbjct: 1567 TYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTI--- 1623 Query: 1223 QTPNNRPPSTEPSEISLSPERL-NASIAGLFPPQINIPLPPRPNLNRG-FDQQGLN-PTT 1279 TP+ P +S +P AS P N P+ ++ +G + PT+ Sbjct: 1624 STPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTS 1683 Query: 1280 LKAIGQAP-SNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSS-PGS- 1336 G+ P +++T+ + A+ L + V++ + R+SP+ S +S P S Sbjct: 1684 TYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNST 1743 Query: 1337 -SRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELP----RNVLVSPTPLANPPVPGSFP 1391 S TTP S P L+ + T +A + P SPT +P S Sbjct: 1744 PSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTS-T 1802 Query: 1392 NNSGLNPQNST-VSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVK 1450 + G+ P ST VS V + V +S S + + PA+ Sbjct: 1803 LSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTA------VSSSPTPAEGTS 1856 Query: 1451 MVVP---EDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAP-TSLSQL------LDNSGA 1500 + E + P + S E N +PA+ P T+ +Q+ D S Sbjct: 1857 IATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSM 1916 Query: 1501 PNVTIKP--PGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSS 1558 P T + P LT + V+ V+ ++ S TL D + + + + +S Sbjct: 1917 PTSTPREGRPPLTSIPVSTTTVASSEINTLST--TLADTRTPVTTYSQASSSPTTADGTS 1974 Query: 1559 LVHPELSEVSSNVAPSIPPVMSRPVSSSSI-STPLPPNQITVFVTSNPITTSANTSAA-- 1615 + P SE S+ P+ S P+S++ + S+ T TS P TTS S++ Sbjct: 1975 MPTPAYSEGST-------PLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPT 2027 Query: 1616 ------LPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQS--NARPQFITPVFINSSSII 1667 + T S + + MP + + V+ SEG + + + +++ Q +SS+ Sbjct: 2028 TAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATA 2087 Query: 1668 QVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNA-------LSS 1720 + + + +PL T+ L VA P+ S+ PV N+ +SS Sbjct: 2088 EGSSMTISAPSEGSPLLTSIPLSTTPVAS------PEASTLSTTPVDSNSPVITSTEVSS 2141 Query: 1721 SPAPNIQTG-RPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSA 1779 SP P T + S R TP L S P +++ V S + + D ++P N++ Sbjct: 2142 SPIPTEGTSMQTSTYSDRRTP--LTSMPVSTTVVASS--AISTLSTTPVDTSTPVTNSTE 2197 Query: 1780 DQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSL 1839 +++ +S+ T+M P T S GS+ PVS+ VT S Sbjct: 2198 ARSSPTTSEGTSM--PTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTST 2255 Query: 1840 EKGEEQYGADGET-------EGQGLDTTAP---GLMGTEQLST----ELDSKTPTPPAPT 1885 E A+G + EG T+ P L+ ++ST +DS TP + Sbjct: 2256 EATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTE 2315 Query: 1886 LLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSN 1936 + P GT+ + G P + + TT+V S S + TT ++ Sbjct: 2316 A--SSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPAD 2364 Score = 78.6 bits (192), Expect = 6e-14 Identities = 215/981 (21%), Positives = 361/981 (36%), Gaps = 170/981 (17%) Query: 1075 SVPVMVSLQGPASVPPS---------PDKQRMP---MPVNTPLGSNSRKMVYQESPQNP- 1121 S P S +G +S + P ++ P MPV+T L +S +P + Sbjct: 2013 STPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSK 2072 Query: 1122 ---------SSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSP 1172 SSS AE +S+ ++ SE + + V P+ + T P SP Sbjct: 2073 TQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSP 2132 Query: 1173 LSA----------TQGATPQ-------QPPVNSLPSSHGHHFPNVAA-----PTQTSRPK 1210 + T+G + Q + P+ S+P S + + P TS P Sbjct: 2133 VITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPV 2192 Query: 1211 TPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGF 1270 T N R + P++ PSE S P ++P+ P + Sbjct: 2193 T-NSTEARSSPTTSEGTSMPTSTPSEGST--------------PFTSMPVSTMPVVTSEA 2237 Query: 1271 DQQGLNP-------TTLKAIGQAPSNL--TMNPSNFATPQTHKLDSVVVNSGKQSNSG-A 1320 P TT +P+ T P++ + T L S+ V+ +NS + Sbjct: 2238 STLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVS 2297 Query: 1321 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLA-----------SQTNAALLQNVE 1369 T +P +S S+ ++P P + + P T + S T A + Sbjct: 2298 TLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETST 2357 Query: 1370 LPRNVLVSPTPLANPPVPGSFPNNS------------GLNPQNSTVSVAAVGGVVEDNKE 1417 L + TP+ GS P + G P S V V+ + V + Sbjct: 2358 LSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTS-VPVSTMPVVSSEAST 2416 Query: 1418 SLNVPQDSDCQ---NSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVE 1474 P D+ ++++ E ++P E + P + S E Sbjct: 2417 HSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPS----EGTTPLASMPVSTTPVVSSE 2472 Query: 1475 ENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTL 1534 +P P + S +S I P T E + + S P Sbjct: 2473 AGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEA 2532 Query: 1535 QDLSSSKEPSNSLNLPHSNELCSSLVHPE-LSEVSSNVAPSIPPVMSRPVSSSSISTPLP 1593 LS++ SNS + S E+ SS E S +S + P+ S PVS+ +++ Sbjct: 2533 STLSTTPVDSNS-PVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEA 2591 Query: 1594 PNQITVFV-TSNPITTSANTSAALPTHLQSAL-MSTVVTMPNAGSKVMVSEGQSAAQSNA 1651 T V TS P+TTS TS++ T +++ +ST + + + ++VS A S A Sbjct: 2592 STLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVST-MPVASSEA 2650 Query: 1652 RPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIP-QNIKFSS 1710 TPV ++ +++ G+ S P T MP S G P NI S+ Sbjct: 2651 STLSTTPV--DTRTLVTTSTGTSSS-----PTTAEGSSMPTSTP--GERSTPLTNILVST 2701 Query: 1711 APVPPNALSSSPAPNIQTGRPLVLSSRA---------TPVQLPSPPCTSSP---VVPSHP 1758 + + S+ + T P+ S+ A T +++ +P S+P ++ S Sbjct: 2702 TLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTL 2761 Query: 1759 PVQQVKELNPDEASPQVNTSADQNTLP--------SSQSTTMVSPLLTNSPGSSGN---- 1806 PV EAS V+T+A ++P SS +T V+ + T++P + Sbjct: 2762 PVAS------SEAS-TVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTS 2814 Query: 1807 ---RRSPVSSSKGKGKVDKIGQILLT--KACKKVTGSLEKGEEQYGADG-------ETEG 1854 +PV+SS+ G + T VT S + A+G +EG Sbjct: 2815 MPVNHTPVASSEA-------GTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEG 2867 Query: 1855 QGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSV 1914 L T+ P + T +++ S T P T + +T+S G +S+ + G ++P S Sbjct: 2868 STLLTSIP--VSTTPVASSEASTLSTTPVDTSIPVTTSTEG---SSSPTTAEGTSMPIST 2922 Query: 1915 RSIVTTLVPSELISAVPTTKS 1935 S V+T + S L+S VP S Sbjct: 2923 PSEVSTPLTSILVSTVPVAGS 2943 Score = 77.4 bits (189), Expect = 1e-13 Identities = 173/914 (18%), Positives = 321/914 (35%), Gaps = 147/914 (16%) Query: 997 PPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP 1056 PP P + P S P S + + P PV+ Sbjct: 3263 PPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTL----STTPADTSTPVTTYSQA 3318 Query: 1057 PRGPLNPDSQRMPMQ--QSGSVPV--MVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKM 1112 P D MP GS P+ M P + P+ +TP+ +++ Sbjct: 3319 SSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEAS 3378 Query: 1113 VYQESPQN---PSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPG 1169 + + + P+SSP L S P V N + S + N L+ T + Sbjct: 3379 LSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTL-STTPVDSNTLVTTSTEAS 3437 Query: 1170 PSPLSA----------TQGATPQQ-PPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPR 1218 SP A ++G+TP P+++ P + P TS P T + Sbjct: 3438 SSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTS----- 3492 Query: 1219 PYYPQTPNNRPPSTEPSEISLSPERLNASIAGL-FPPQINIPLPPRPNLNRGFDQQGLNP 1277 +P N P+T +E++ P S AG P N+P+ P + P Sbjct: 3493 -----SPTNSSPTT--AEVTSMP----TSTAGEGSTPLTNMPVSTTPVASSEASTLSTTP 3541 Query: 1278 -------TTLKAIGQAPSNLTMNPSNFATPQ--THKLDSVVVNSGKQSNSGATKRASPSN 1328 T+ +P+ L + +TP + L +++++S ++S A+ ++PS Sbjct: 3542 VDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSV 3601 Query: 1329 SRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVS--------PTP 1380 R + +S ++ +P ++ S+ + L +V +S P Sbjct: 3602 DRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVD 3661 Query: 1381 LANPPVPGSFPNNSGLNPQNSTVSV--------------AAVGGVVEDNKESLNVPQ--- 1423 + P + + ++S + P+ +T+ + + V +L+ P Sbjct: 3662 TSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVT 3721 Query: 1424 ------------DSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLP 1471 S +S + + +E+ + + P + + PS P+ Sbjct: 3722 STPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYT 3781 Query: 1472 SVE---ENKNLVSPAMREAPTSL--------SQLLDNSGAPNVTIKPPGLTDLEVTPPVV 1520 S+ ++ SP E T++ S LL +++ P TPP Sbjct: 3782 SMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGD 3841 Query: 1521 SGEDLKKASV-----IP---TLQDLSSSKEPSNSLN-------LPHSNELCSSLVHPELS 1565 + L ++ IP T +S + E S L LP S S P L Sbjct: 3842 TSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPL- 3900 Query: 1566 EVSSNVAPSI-----PPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL 1620 + S+ PS P + S S+ T T+F+ S P+T+S T+ P Sbjct: 3901 DTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSS--TADVFPA-T 3957 Query: 1621 QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA 1680 A+ + V+T + S + + S + +F TP ++ + V + PST Sbjct: 3958 TGAVSTPVITSTELNTPSTSSSSTTTSFSTTK-EFTTPAMTTAAPLTYVTMSTAPST--- 4013 Query: 1681 APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPA-PNIQTGRPLVLSSRAT 1739 P TT+ G + + +S P ++++ P P+ ++ RP ++S Sbjct: 4014 -PRTTSRGCTTSA----------STLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTI 4062 Query: 1740 PVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTN 1799 P P P+H + +P+ T+ T PS+++T+ + T Sbjct: 4063 PPTFP----------PAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTA 4112 Query: 1800 SPGSSGNRRSPVSS 1813 P ++ + +P S+ Sbjct: 4113 VPTNTTIKSNPTST 4126 Score = 61.6 bits (148), Expect = 8e-09 Identities = 135/649 (20%), Positives = 248/649 (38%), Gaps = 67/649 (10%) Query: 1469 KLPSVEENKNLVSPAM---REAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDL 1525 ++ S+E + +P + R PT S+ S + + T+ P D +P G D+ Sbjct: 90 EMTSIESSVTSDTPGVSSTRMTPTE-SRTTSESTSDSTTLFPSSTEDTS-SPTTPEGTDV 147 Query: 1526 KKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVH------PELSEVSSNVAPSIPPVM 1579 ++ P+ + +SS+ ++ LP S E +SL + P + ++ +P+ P Sbjct: 148 PMST--PSEESISSTMAFVSTAPLP-SFEAYTSLTYKVDMSTPLTTSTQASSSPTTPEST 204 Query: 1580 SRPVSSSSI-STPLPP-----------NQITVFVT----SNPITTSANTSAALPTHLQSA 1623 + P S++S STPL IT+ T S P+T SA S++ PT + Sbjct: 205 TIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSS-PTTAEGP 263 Query: 1624 LMSTVVTMPNAGSKVMVSEGQSA---AQSNARPQFITPVFINSSSIIQVMKGSQPST--- 1677 +S + P+ GS + S S A TP N I S P+T Sbjct: 264 SLSN--SAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEG 321 Query: 1678 --IPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNAL-SSSPAPNIQTGRPLVL 1734 IP + T S + + A P+ + S PV + L ++S P+ Sbjct: 322 TSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEAT 381 Query: 1735 SSRATPVQLPSPPCTSSPVVPSHPPVQQVKELN--PDEASPQVNTSADQNTLPSSQSTTM 1792 S + + S P T+ PV + + P ++ V T+++ ++ P++ T Sbjct: 382 SMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTS 441 Query: 1793 V--------SPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLT--KACKKVTGSLEKG 1842 + S LT+ P S+ S +S+ VD Q+ + + T + Sbjct: 442 IATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSM 501 Query: 1843 EEQYGADGETEGQGLDTTAPGLMGTEQ---LSTELDSKTPTPPAPTLLKMTSSPVGPGTA 1899 ++G T + + + +E +T +D+ TP + +++P G Sbjct: 502 PTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIP 561 Query: 1900 SAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGG-IASESLAGGLVEEKVGSHP 1958 ++ PS G+ P + + T LV S S TT ++ + + S A G+ Sbjct: 562 TSTPS--EGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSM 619 Query: 1959 ELLPSIAPSQNLVSKETSTTALQASVA-----RPELEVNAAIVSGQSSEPKEIVEKSKIP 2013 + S STT + +S A P S +++ E + +P Sbjct: 620 PTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMP 679 Query: 2014 GRRNSRTEEPTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRKS 2062 ++ TE T + N SS ++ S++ D ++ V + S Sbjct: 680 --TSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEAS 726 Score = 40.0 bits (92), Expect = 0.024 Identities = 39/142 (27%), Positives = 54/142 (38%), Gaps = 12/142 (8%) Query: 334 SLGTMTANQGWKKAPLPG-PMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQ 392 S+ T TA +G PL P+ A +T+ T + S QAS + Sbjct: 3506 SMPTSTAGEG--STPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATL-- 3561 Query: 393 MSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQ 452 Q T +M + G S + T L S AS+PS+ S+P TQ Sbjct: 3562 -----QVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPST--PSVDRSTPVTTSTQSN 3614 Query: 453 MGPRPPQNNPLPQGFQQPVSSP 474 P PP+ LP VS+P Sbjct: 3615 STPTPPEVITLPMSTPSEVSTP 3636 Score = 32.7 bits (73), Expect = 3.8 Identities = 35/149 (23%), Positives = 51/149 (34%), Gaps = 12/149 (8%) Query: 326 LQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQ 385 L P S T+ + +P + PS T S P P S +AS Sbjct: 1357 LSTTPVDNSTPVTTSTEACS-SPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEAST 1415 Query: 386 AHTNFPQMSNPGQFTAPQMKSLQGG---------PSRVPTPLQQPHLTNKSPASSPSSFQ 436 S PG +A S PS TPL+ ++N A+S +S Sbjct: 1416 LSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTL 1475 Query: 437 QGSP--ASSPTVNQTQQQMGPRPPQNNPL 463 +P ++SP V T P P + + Sbjct: 1476 STTPVDSNSPVVTSTAVSSSPTPAEGTSI 1504 >gi|33286444 mastermind-like 2 [Homo sapiens] Length = 1156 Score = 91.3 bits (225), Expect = 9e-18 Identities = 168/696 (24%), Positives = 232/696 (33%), Gaps = 128/696 (18%) Query: 145 QDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQ 204 Q M G G ++ A + +GP V++ S P+P ++ Sbjct: 493 QSSPMPGVAGGSGQSKVMANYMYKAGPSA--QGGHLDVLMQQKPQDLSRSFINNPHPAME 550 Query: 205 PRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQ 264 PR L + Q + S+ P + + +Q Q QQQQ Sbjct: 551 PRQGNTKP--------LFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQ----QQQQQQ 598 Query: 265 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSG 324 QQQQQQQQQQQQQQQQQQQQQ Q+ Q QQQQ I Q Q Q Sbjct: 599 QQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQ 658 Query: 325 ALQPPPAQGSLGTMT-ANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQA 383 Q S + +Q ++PLP LQ + L +Q Y QQ Sbjct: 659 QQQQQQQPSSQPAQSLPSQPLLRSPLP------LQQKLLLQQMQNQPIAGMGYQVSQQQR 712 Query: 384 SQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASS 443 H S GQ T GPS P P P+ + S S Q Sbjct: 713 QDQH------SVVGQNT---------GPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKK 757 Query: 444 PTVNQ----------TQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQ 493 T+ + QQQM + P Q + +S P PP++ + Sbjct: 758 QTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQ-INRHLSRP-----------PPDYKDQR 805 Query: 494 QQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPN-FMQGQVPSTTATTPGNS------GA 546 + N P + + G G S N N + V + T TP +S G Sbjct: 806 RNVGNMQPTAQYSG----------GSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGT 855 Query: 547 PQLQANQNVQHAGGQGAGP-----------PQNQMQVSHGP---------PNMMQPSLMG 586 + VQ+ G G P NQ+ P P M +P +G Sbjct: 856 RMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLG 915 Query: 587 IHGNMN--NQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNP 644 N N AG+ G Q N+ PP + + + Q+GT + Sbjct: 916 PSNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGT-SK 974 Query: 645 QNPMILSRAQLMPQGQMMVNPPSQNLGP-------SPQRMTPPKQMLSQQGPQMMAPHNQ 697 Q + S P G P+Q+L S + + PP Q+ M P NQ Sbjct: 975 QQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTP---AVQMRPMNQ 1031 Query: 698 M--------MGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPG--PAQIMRGP 747 M MGP + L+ N + QI+ N Q ++ N P P+ P Sbjct: 1032 MSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNF---P 1088 Query: 748 TPNMQGNMVQFTGQMS-------GQMLPQQGPVNNS 776 +PN Q T S Q GP NS Sbjct: 1089 SPNQSSRAFQGTDHSSDLAFDFLSQQNDNMGPALNS 1124 Score = 71.2 bits (173), Expect = 1e-11 Identities = 233/1110 (20%), Positives = 369/1110 (33%), Gaps = 198/1110 (17%) Query: 364 ATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQ---MKSLQGGPSRVPTPLQQ 420 AT T + PPPP P ASQA P Q + S G S QQ Sbjct: 97 ATAATTTAPPPP-PAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQ 155 Query: 421 PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSP------ 474 P PAS+P Q+ S + + ++Q+ P N+ P GF Sbjct: 156 P------PASTPGD-QRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRV 208 Query: 475 GRNPMVQQGNVPPN---------FMVMQQQP---PNQGPQSLHPGLGGMPKRLPPGFSAG 522 G N QG + N + M Q P N P H G+ F+ G Sbjct: 209 GENLSAGQGGLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGL-------FNMG 261 Query: 523 QANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQP 582 G+ S + G + N+ G Q P ++ + N+ P Sbjct: 262 LKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQEL--FNELTNISVP 319 Query: 583 SLMGIH-GNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGT 641 + + NM N ++L Q Q+ P + M + ++ S+ QG Sbjct: 320 PMSDLELENMINATIKQDDPFNIDLGQ---QSQRSTPRPSLPMEKIVIKSEYSPGLTQG- 375 Query: 642 LNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGP 701 P G + PPS GP+ + LS P P +Q Sbjct: 376 ---------------PSGSPQLRPPSA--GPA---FSMANSALSTSSPIPSVPQSQAQPQ 415 Query: 702 QGQVLLQQNP---------MIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQ 752 G + P ++QI N+ Q + Q + Q GP+P Sbjct: 416 TGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPF 475 Query: 753 GNMVQFTGQMSGQML--PQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQ---QHGDPATT 807 G + GQ PQ P+ V G GQ S MA + G A Sbjct: 476 GQE-KIPSPSFGQQTFSPQSSPMPG----VAGGSGQ-------SKVMANYMYKAGPSAQG 523 Query: 808 ANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMS 867 + DV + Q D+S N P ++ QGN+ HF+ + P S P+ N+ S Sbjct: 524 GHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMP-SVLPSQNKPS 582 Query: 868 C--------------GQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNK----QNNT 909 Q + QS ISA Q Sbjct: 583 LLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQ 642 Query: 910 NANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEAD---QPPLPGEQGINLDNSGPKLPEF 966 + ++++ ++++ QQ P ++PA + + PLP +Q + L + Sbjct: 643 QQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQ-------QM 695 Query: 967 SNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQP-PQQQPQP--------QLPQQQQPPP 1017 N+P V Q+ Q + Q+ P P P P P Q QQ Sbjct: 696 QNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMG 755 Query: 1018 PSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVP 1077 Q +Q +Q+QQ+++ M D + + N H R P + QR + G++ Sbjct: 756 KKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQR---RNVGNMQ 812 Query: 1078 VMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASG 1137 G +S Q + PV+T + P+SS L+ + G Sbjct: 813 PTAQYSGGSSTISLNSNQALANPVST------------HTILTPNSSLLS------TSHG 854 Query: 1138 SEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHF 1197 + PS+ NM + LP NQ P+ S T G +N L Sbjct: 855 TRMPSLSTAVQNMGMYGNLPCNQ---------PNTYSVTSG-------MNQL-------- 890 Query: 1198 PNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQIN 1257 TQ PK P P RPP+ PS N ++A + Sbjct: 891 ------TQQRNPKQLLANQNNPMMP-----RPPTLGPSN--------NNNVATFGAGSVG 931 Query: 1258 IPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSN 1317 RPNL T+ I ++ T P+ + T K + ++G + Sbjct: 932 NSQQLRPNLTHSMASMPPQRTSNVMI----TSNTTAPNWASQEGTSKQQEALTSAGVRFP 987 Query: 1318 SGATKRASPSNSRRSSPGSSR--KTTPSPGRQNSKAPKLTLASQTNAALLQNVELP-RNV 1374 +G +P+ S + + GS + + +P Q + A ++ +Q + L P R + Sbjct: 988 TGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTLNGQTMGPLRGL 1047 Query: 1375 LVSPTPLANPPVPGSFPNNSGLNPQNSTVS 1404 + P L+ +P + +GLN + ++ Sbjct: 1048 NLRPNQLSTQILPNLNQSGTGLNQSRTGIN 1077 Score = 69.7 bits (169), Expect = 3e-11 Identities = 191/847 (22%), Positives = 283/847 (33%), Gaps = 140/847 (16%) Query: 292 QQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQ-PPPAQGSLGTMTANQGWKKAPLP 350 QQ Q+ P+ P + PG Q PSG+ Q PP+ G +M + +P+P Sbjct: 346 QQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIP 405 Query: 351 GPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGG 410 Q Q Q P AS+A ++ ++S+ Q Q+ + + Sbjct: 406 SVPQSQAQ------------------PQTGSGASRALPSWQEVSHAQQL--KQIAANRQQ 445 Query: 411 PSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQP 470 +R+ QQ TN S S S SP GP + P P F Q Sbjct: 446 HARMQQHQQQHQPTNWSALPS-------SAGPSP---------GPFGQEKIPSP-SFGQQ 488 Query: 471 VSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQ 530 SP +PM VM GP + L + ++ P S +F+ Sbjct: 489 TFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSR-----SFIN 543 Query: 531 GQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGN 590 P+ GN+ P N + Q Q+ P+ +PSL+ Sbjct: 544 NPHPA-MEPRQGNT-KPLFHFNSD------------QANQQMPSVLPSQNKPSLLHYTQQ 589 Query: 591 MNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMIL 650 QQ Q Q Q QQ Q QQ S Q QQQ +++ Q Sbjct: 590 QQQQQQ-----QQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQ 644 Query: 651 SRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQN 710 + Q Q Q Q PS Q P Q L Q P + +P + LQQ Sbjct: 645 QQQQQQQQQQQQQQQQQQQQQPSSQ----PAQSLPSQ-PLLRSP----------LPLQQK 689 Query: 711 PMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQ 770 +++Q+ + G Q + Q + + Q GP+P+ TG SG M QQ Sbjct: 690 LLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQ-NTGPSPSPNPCSNPNTG--SGYMNSQQ 746 Query: 771 GPVNNSPSQVMG----IQGQVLRPPGPSPHMAQQHGDPATTANNDV---SLSQMMPDVSI 823 +N Q+MG +Q Q++ Q D A D LS+ PD Sbjct: 747 SLLN---QQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKD 803 Query: 824 QQTNM--VPPHVQ--------AMQGNSASGNHFSGHG-MSFNAPFSGAPNGNQM------ 866 Q+ N+ + P Q ++ N A N S H ++ N+ +G +M Sbjct: 804 QRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTA 863 Query: 867 --SCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKK 924 + G P N+ T + +N L N KQ N N P +PP Sbjct: 864 VQNMGMYGNLPCNQPNTYSVTSGMNQLTQQ-------RNPKQLLANQNNPMMPRPPTLGP 916 Query: 925 NSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSN-RPPGYPSQPVEQRPL 983 ++ ++ T G + +P L + SN P + SQ + Sbjct: 917 SNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQ 976 Query: 984 QQMP------PQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML 1037 + + P P Q QQ Q Q+ PP+Q Q + QM L Sbjct: 977 EALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTL 1036 Query: 1038 MMQQDPKSVRLPVSQNVHPPRG----PLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPD 1093 Q + P RG P +Q +P + S G + PPS Sbjct: 1037 N------------GQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTG-INQPPSLT 1083 Query: 1094 KQRMPMP 1100 P P Sbjct: 1084 PSNFPSP 1090 Score = 63.9 bits (154), Expect = 2e-09 Identities = 139/658 (21%), Positives = 217/658 (32%), Gaps = 121/658 (18%) Query: 949 PGEQGINLDNSGPKLPE-----FSNRP-PGYPSQPVEQRPL---------QQMPPQLMQH 993 P QG +LD + P+ F N P P + +PL QQMP L Sbjct: 519 PSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQ 578 Query: 994 VAPP----PQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLP 1049 P Q QQQ Q Q QQQQ Q Q QQQQQQQQQ + QQ +S Sbjct: 579 NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISA 638 Query: 1050 VSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNS 1109 Q + Q+ QQ P PA PS R P+P+ Sbjct: 639 QQQQQQQQQQQQQQQQQQQQQQQQQQQP----SSQPAQSLPSQPLLRSPLPL-------Q 687 Query: 1110 RKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPG 1169 +K++ Q+ P + +++ H V+ QN TGP P Sbjct: 688 QKLLLQQMQNQPIAGMGYQVSQ---------------QQRQDQHSVVGQN----TGPSPS 728 Query: 1170 PSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 P+P S PN + S+ N + + + Sbjct: 729 PNPCSN----------------------PNTGSGYMNSQQSLLN----QQLMGKKQTLQR 762 Query: 1230 PSTEPSEISLSPERLNASIAGLFP-PQIN--IPLPPRPNLNRGFDQQGLNPTTLKAIGQA 1286 E + L +++ A + P QIN + PP ++ + + PT + G + Sbjct: 763 QIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSS 822 Query: 1287 PSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGR 1346 +L N + TH + + NS S S T+ S S + ++ P Sbjct: 823 TISLNSNQALANPVSTHTI--LTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNT 880 Query: 1347 QNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVA 1406 + + L Q N P+ +L + P P P+N N+ V+ Sbjct: 881 YSVTSGMNQLTQQRN---------PKQLLANQNNPMMPRPPTLGPSN------NNNVATF 925 Query: 1407 AVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVV------PEDQSKK 1460 G V NSQ + + + ++P Q V+ + + + Sbjct: 926 GAGSV----------------GNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQ 969 Query: 1461 DGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPG-LTDLEVTPPV 1519 +G L S +PA SL Q + + + PP LT P+ Sbjct: 970 EGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPM 1029 Query: 1520 VSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPP 1577 + L+ L+ ++ LP+ N+ + L S N PS+ P Sbjct: 1030 NQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGL---NQSRTGINQPPSLTP 1084 Score = 60.8 bits (146), Expect = 1e-08 Identities = 156/705 (22%), Positives = 220/705 (31%), Gaps = 156/705 (22%) Query: 197 PGPNPELQPRTPRPA-----SQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQ 251 P +P+L+P + PA S P+ S Q Q + Q VS Sbjct: 376 PSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVS---- 431 Query: 252 MNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQ 311 QQ +Q +QQ + QQ Q QQHQ Sbjct: 432 ------------HAQQLKQIAANRQQHARMQQHQ------QQHQ---------------- 457 Query: 312 VPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLA-TVQTPS 370 P W+ LPS A P PGP Q+ PS +P Sbjct: 458 ---PTNWSALPSSA---------------------GPSPGPFGQEKIPSPSFGQQTFSPQ 493 Query: 371 HPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRV-----PTPLQQPHLTN 425 P P G S+ N+ + P S QGG V P L + + N Sbjct: 494 SSPMPGVAGGSGQSKVMANYMYKAGP---------SAQGGHLDVLMQQKPQDLSRSFINN 544 Query: 426 KSPASSPSSFQQGS--PASSPTVNQTQQQM-GPRPPQNNPLPQGFQQPVSSPGRNPMVQQ 482 PA P +QG+ P +Q QQM P QN P + Q + QQ Sbjct: 545 PHPAMEP---RQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQ 601 Query: 483 GNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPG 542 QQQ Q QS SA Q Q Q S +A Sbjct: 602 QQQQQQQQQQQQQQQQQQQQS--------------SISAQQ-----QQQQQSSISAQQQQ 642 Query: 543 NSGAPQLQANQNVQHAGGQGAGPPQNQMQVS-------HGPPNMMQPSLMGIHGNMNNQQ 595 Q Q Q Q Q P +Q S P + Q L+ M NQ Sbjct: 643 QQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLL---QQMQNQP 699 Query: 596 AGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVP------SQGQMVQQQGTLNP----- 644 G +S Q Q Q Q G P G M QQ LN Sbjct: 700 IAGMG---YQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGK 756 Query: 645 ----QNPMILSRAQLMPQGQMMVNPPSQNLGPSPQ-----RMTPPKQMLSQQGPQMMAPH 695 Q ++ + QL+ Q QM+ + ++ + P Q PP ++ M P Sbjct: 757 KQTLQRQIMEQKQQLLLQQQMLAD--AEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPT 814 Query: 696 NQMMGPQGQVLLQQN-PMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQI-----MRGPTP 749 Q G + L N + + T+ + + + MP + M G P Sbjct: 815 AQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLP 874 Query: 750 NMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTAN 809 Q N T M+ L QQ +P Q++ Q + P P+ + + A Sbjct: 875 CNQPNTYSVTSGMN--QLTQQ----RNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAG 928 Query: 810 NDVSLSQMMPDVSIQQTNMVPPHVQ--AMQGNSASGNHFSGHGMS 852 + + Q+ P+++ +M P + N+ + N S G S Sbjct: 929 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTS 973 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 87.8 bits (216), Expect = 1e-16 Identities = 310/1521 (20%), Positives = 498/1521 (32%), Gaps = 325/1521 (21%) Query: 227 QQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQ------ 280 ++Q P G + PP P + +Q P P LQQ + QQ ++ + Q Sbjct: 198 KEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDP-LQQDGTPKSISSQQPEKIKSQPPGTGK 256 Query: 281 ------QQQQQLQARPPQQHQQQQPQ----------GIRPQFTAPTQVPVPPGWNQLPSG 324 Q Q A+ P Q +PQ ++P +P++ P+ Q P+ Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPI-----QQPTP 311 Query: 325 ALQPPPAQGSLGTMTANQGWKKAPL-PGPMQQQLQARPSLATVQTPSHP-----PPPYPF 378 PPAQ G + G K P P + + L +P TV+ P P PP P Sbjct: 312 G--KPPAQ-QPGHEKSQPGPAKPPAQPSGLTKPLAQQP--GTVKPPVQPPGTTKPPAQPL 366 Query: 379 GSQQ--ASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQ 436 G + A Q + P PG P L QP K+PA Q Sbjct: 367 GPAKPPAQQTGSEKPSSEQPG-----------------PKALAQPPGVGKTPA------Q 403 Query: 437 QGSPASSPTVNQTQQQMG-PRPPQNNPLPQGFQQPVSSPG--RNPMVQQGNVPPNFMVMQ 493 Q PA PT QQ+G P+P P G Q P +PG + P+ Q G P Q Sbjct: 404 QPGPAKPPT-----QQVGTPKPLAQQP---GLQSPAKAPGPTKTPVQQPG--PGKIPAQQ 453 Query: 494 QQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQ 553 P Q P PP G A P Q PG + P Q Sbjct: 454 AGPGKTSAQQTGP-------TKPPSQLPGPAKPPPQQ----------PGPAKPPPQQPG- 495 Query: 554 NVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQP 613 A PP Q + PP P+ + QQ G++ P + + Sbjct: 496 --------SAKPPSQQPGSTKPPPQQPGPA------KPSPQQPGSTKPPSQQPGSAKPSA 541 Query: 614 QQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPS 673 QQ P++ Q P V Q G+ P P +S P + PPSQ L + Sbjct: 542 QQPSPAK-PSAQQSTKP-----VSQTGSGKPLQPPTVS-----PSAK---QPPSQGLPKT 587 Query: 674 PQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQV--LLQQNPMIEQIMTNQMQGNKQQFNTQ 731 + ++L + A N Q V L NP + Q Sbjct: 588 ICPLCNTTELLLHVPEK--ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRA 645 Query: 732 NQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPP 791 ++ P P+ P P ++ V T +S + PQ P SP + + + + P Sbjct: 646 LGGDLAPVPS----SPQPKLKTAPVTTTSAVS-KSSPQ--PQQTSPKKDAAPKQDLSKAP 698 Query: 792 GPS--PHMAQQ---HGDPATTANNDV---SLSQMMP----------------DVSIQQTN 827 P P + +Q HG P+ A SLS+ P D +Q Sbjct: 699 EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPK 758 Query: 828 MVPPHVQAMQGNSASGN-HFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPV--NKDVTLTS 884 MV P + +SA+ + A P S + FP K S Sbjct: 759 MVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDS 818 Query: 885 PLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEAD 944 + H G +++ P +KK KK ++ PD +P + + Sbjct: 819 KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS-PKPDAKPMP-KGSP 876 Query: 945 QPPLP---GEQGINLDNSGPKLPEFSNR-----------PPGYPSQPVEQRPLQ------ 984 PP P Q + PK E S R P P+ P E + Sbjct: 877 TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936 Query: 985 QMPPQLMQHVAPPPQP-PQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDP 1043 + Q ++ QP P Q P P +Q P P P SQ Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP----------------- 979 Query: 1044 KSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPS-----PDKQRMP 1098 P S PP ++ +P+++ P L+ A P+ +K+ P Sbjct: 980 -----PKSTGQAPP-----APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029 Query: 1099 MPVNTPLGSNSRKMV----YQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHV 1154 + + L + +K V ++SP+ S+ PL + +E P N + Sbjct: 1030 IKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK---------TELNIGSKDPPNFNTCT 1080 Query: 1155 VLPQNQLMMTGPKPGP----------------SPLSATQGATPQQPPVNSLPSSHGHHFP 1198 + G P P +S G + PP S P + Sbjct: 1081 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKA-----S 1135 Query: 1199 NVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINI 1258 + PT++S KT A P + TE ++ L + S+ Sbjct: 1136 PMPVPTESSSQKT---AVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSME--------- 1183 Query: 1259 PLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNS 1318 +PP ++ ++ L A+ + P+ KL + Sbjct: 1184 KIPPMVTTDQKQEESKLEKDKASALQEKK----------PLPEEKKLIPEEEKIRSEEKK 1233 Query: 1319 GATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSP 1378 + P+ + ++ + P + + ++ +A + L+ P+ V Sbjct: 1234 PLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEK----LEGRVAPKTVQEGK 1289 Query: 1379 TPLAN-PPVPGSFPNNSGLNPQNSTVSV--------AAVGGVVEDNKESLNVPQD-SDCQ 1428 P +P P + +T ++ A VE KE D SD Sbjct: 1290 QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTS 1349 Query: 1429 NSQSRK------------EQVNIELKAVPA------QEVKMVVPEDQSKKDGQPSDPNKL 1470 +SQ K + ++ L +P+ +++ + +D ++ PS P+ L Sbjct: 1350 SSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDL 1409 Query: 1471 PSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPV-------VSGE 1523 +E ++S +A T + + P+ + P D E T + +S E Sbjct: 1410 AKLE--STVLSILEAQASTLADEKSEKKTQPH-EVSPEQPKDQEKTQSLSETLEITISEE 1466 Query: 1524 DLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPV 1583 ++K+ S +E ++ ++ SS H E SE ++ P S Sbjct: 1467 EIKE-----------SQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEE 1515 Query: 1584 SSSSISTPLPPNQITVFVTSN 1604 SS S ++P+P + V S+ Sbjct: 1516 SSESENSPVPQRKRRTSVGSS 1536 Score = 87.4 bits (215), Expect = 1e-16 Identities = 322/1521 (21%), Positives = 503/1521 (33%), Gaps = 290/1521 (19%) Query: 649 ILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQ 708 ++ + Q P+G ++ PP Q PPK + QQGP G+ LQ Sbjct: 195 VVQKEQGKPEG--IIKPPLQQ--------QPPKPIPKQQGP-------------GRDPLQ 231 Query: 709 QNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLP 768 Q+ + I + Q + K Q PG + ++GPT Q + + Q P Sbjct: 232 QDGTPKSISSQQPEKIKSQ---------PPGTGKPIQGPTQTPQTDHAKLPLQRDASR-P 281 Query: 769 QQG-----------PVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQM 817 Q P SPS+ Q +PP P + PA L++ Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341 Query: 818 MPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVN 877 + QQ V P VQ P A Q + + P Sbjct: 342 LA----QQPGTVKPPVQPPGTTKPPAQ-----------PLGPAKPPAQQTGSEKPSSEQP 386 Query: 878 KDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNS------QQDLN 931 L P V T A +P KPP ++ + Q L Sbjct: 387 GPKALAQPPGVG------------------KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428 Query: 932 TPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLM 991 +P P + Q P PG+ I +GP + S + G P++P Q P PP Sbjct: 429 SPAKAPGPTKTPVQQPGPGK--IPAQQAGPG--KTSAQQTG-PTKPPSQLPGPAKPPPQQ 483 Query: 992 QHVAPPPQPPQQQPQPQLPQQQQP----PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVR 1047 P +PP QQP P QQP PPP QP + QQ P S + Sbjct: 484 PG---PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ------------PGSTK 528 Query: 1048 LPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQG----PASVPPS---PDKQRMPMP 1100 P SQ + S P Q + PV + G P +V PS P Q +P Sbjct: 529 -PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT 587 Query: 1101 VNTPLGSNSRKMVYQESP--------------------QNPSSSPLAEM----ASLPEAS 1136 + PL + + +++ NP + + E + A Sbjct: 588 I-CPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRAL 646 Query: 1137 GSEAPSVPGGPN--------NMPSHVVLPQNQLMMTGPKPGPSPLSATQGA--TPQQPPV 1186 G + VP P S V Q T PK +P A + PP+ Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706 Query: 1187 NSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNA 1246 P+ HG P P+ + + P P P E S+ E+ A Sbjct: 707 VKQPTLHGSPSAKAKQP-----PEADSLSKPAP--------------PKEPSVPSEQDKA 747 Query: 1247 SIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLD 1306 +A P Q + P D + T K PS+ + + T K D Sbjct: 748 PVADDKPKQPKMVKPTT-------DLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLKTD 798 Query: 1307 SVVVNSGKQSNSGATKRASPSNSRR-SSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALL 1365 S QS ++ SP +S+ P S K PG P Q + Sbjct: 799 SA---KPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG------PSSESKGQKQVDPV 849 Query: 1366 QNVELPR--NVLVSPTPLANPPVPGSFPNNSGLNP---QNSTVSVAAVGGVVEDNKESLN 1420 Q E P+ +SP P A P GS P G P Q + + + SLN Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPKGS-PTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908 Query: 1421 VPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLV 1480 + +D SQ Q + K + GQP ++ K Sbjct: 909 LGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ-- 966 Query: 1481 SPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSS 1540 +PA + PTS AP K + P E KA PT++ + Sbjct: 967 APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLE--PKAEQAPTVKRTETE 1024 Query: 1541 KEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSS--SISTPLPPNQIT 1598 K+P P + S P+ + + + + S P + P+ + +I + PPN T Sbjct: 1025 KKP------PPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078 Query: 1599 VFVTSN-----------PITTSANTSAALPTHLQSAL---MSTVVTMPNAGSKVMVSEGQ 1644 N P T L Q A+ + + MP A S S Sbjct: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP 1138 Query: 1645 SAAQSNARPQFITP-VFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIP 1703 +S+++ + P V + +V ++ + T + +PP V Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVT-------- 1190 Query: 1704 QNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQV 1763 + + L A +Q +PL + P + P++ P + Sbjct: 1191 -----TDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPED 1245 Query: 1764 KELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKI 1823 K+L P+ TSA P Q ++ + + R +P + +GK K+ Sbjct: 1246 KKL-----LPEAKTSA-----PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKM 1295 Query: 1824 GQI------LLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELD-S 1876 + L K K T ++ K + Q + D PG TE+ + D S Sbjct: 1296 EGLPSGTPQSLPKEDDKTTKTI-KEQPQPPCTAKP-----DQVEPGKEKTEKEDDKSDTS 1349 Query: 1877 KTPTPPAPTLLKMTSSPVGPGTASAG--PSLPGGALPTSVRSIVTTLVPSELI-SAVPTT 1933 + P +P L T ++S G PSL +PT + I+ L + P++ Sbjct: 1350 SSQQPKSPQGLSDTGYSSDGISSSLGEIPSL----IPTDEKDILKGLKKDSFSQESSPSS 1405 Query: 1934 KSNHGGIAS------ESLAGGLVEEKVGSHPELLP-SIAPSQNLVSKETSTTALQASVAR 1986 S+ + S E+ A L +EK S + P ++P Q ++T + + + Sbjct: 1406 PSDLAKLESTVLSILEAQASTLADEK--SEKKTQPHEVSPEQPKDQEKTQSLSETLEITI 1463 Query: 1987 PELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPT-----VASESVENGHRKRSSRP 2041 E E+ KE E+ K +++S+ + P+ SE V++ +R Sbjct: 1464 SEEEI------------KESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYD 1511 Query: 2042 ASASSSTKDITSAVQSKRRKS 2062 + SS + + Q KRR S Sbjct: 1512 SVEESSESENSPVPQRKRRTS 1532 Score = 84.7 bits (208), Expect = 8e-16 Identities = 321/1524 (21%), Positives = 510/1524 (33%), Gaps = 284/1524 (18%) Query: 308 APTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQ 367 +P+ +P G + L + M+ QG K +P + PS+ Q Sbjct: 31 SPSHTAIPAGM-EADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAES----PSMHRKQ 85 Query: 368 T--PSHPP-----PPYPF-----GSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP 415 SHPP PP P G ++ T + PG+ +P SL+ SR Sbjct: 86 ELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR--SPSTISLKESKSR-- 141 Query: 416 TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVS--- 472 T L++ H ++ P S A S VN+ NP S Sbjct: 142 TDLKEEHKSSMMPGFL--SEVNALSAVSSVVNKF-----------NPFDLISDSEASQEE 188 Query: 473 SPGRNPMVQQGNVPPNFMV---MQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFM 529 + + +VQ+ P ++ +QQQPP P+ PG + + P + Q P + Sbjct: 189 TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQ-QPEKI 247 Query: 530 QGQVPSTTATTPGNSGAPQLQ-ANQNVQHAGGQGAGPPQNQMQVSHGP---PNMMQPSLM 585 + Q P T G + PQ A +Q + P Q + G P++ PS Sbjct: 248 KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR---PQTKQADIVRGESVKPSLPSPSKP 304 Query: 586 GIHGNMNNQQAGTSGVPQVNLSNMQGQPQQG-PPSQLMGMHQQIVPSQGQM---VQQQGT 641 I QQ P + + QP PP+Q G+ + + G + VQ GT Sbjct: 305 PI------QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT 358 Query: 642 -------LNPQNPMILSRAQLMPQGQM-----MVNPP------SQNLGPSP---QRMTPP 680 L P P P + + PP +Q GP+ Q++ P Sbjct: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418 Query: 681 KQMLSQQGPQMMAPHNQMMGPQGQVLLQQNP-MIEQIMTNQMQGNKQQFNTQNQSNVMPG 739 K + Q G Q A + GP + Q P I + + QQ + +PG Sbjct: 419 KPLAQQPGLQSPA---KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475 Query: 740 PAQI---MRGPT--PNMQGNMVQFTGQMSGQMLP---QQGPVNNSP---------SQVMG 782 PA+ GP P Q + Q G P Q GP SP SQ G Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535 Query: 783 IQGQVLRPPGPSPHMAQQHGDPATTANNDVSL-------------SQMMPDVSIQQTNM- 828 + P P+ AQQ P + + L SQ +P N Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595 Query: 829 -----VPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQN----------PG 873 VP S G + N + ++C P Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655 Query: 874 FPVNK----DVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQD 929 P K VT TS + + Q ++ KQ+ + A +PKK P K+ Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715 Query: 930 LNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPP---GYPSQPVEQRPLQQM 986 + +P + +P P E P +P ++ P P QP +P + Sbjct: 716 PSAKAKQPPEADSLSKPAPPKE---------PSVPSEQDKAPVADDKPKQPKMVKPTTDL 766 Query: 987 PPQLMQHVAPPPQPPQQQPQPQLPQQQQPP--PPSQPQSQQQQQQQQQMMMMLMMQQDPK 1044 P P + Q Q ++ PP S SQ +++ D K Sbjct: 767 VSS--SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-----DSK 819 Query: 1045 SVRLPVSQN---VHP-PRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMP 1100 ++ P S + HP P Q P+Q+ + + P PD + PMP Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEE-----PKKAQTKMSPKPDAK--PMP 872 Query: 1101 VNTPLGSNSRKMVYQESP---QNPSSSPLAEMASLPEASGSEAP---------SVPGGPN 1148 +P R Q P Q+P + SL S ++AP +V G Sbjct: 873 KGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932 Query: 1149 NMPSHVVLPQNQLMMTGPKPGPSPLSA-----TQGATPQQPPVNSLPSSHGHHFP----- 1198 + + + L+ T +PGP S Q P QPP + P P Sbjct: 933 GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992 Query: 1199 NVAAPTQTSRP---KTPNRASPRPYYPQTPNNR--PPSTEPSEISLSPER--LNASIAGL 1251 ++ +T P K +A P +T + PP + ++ P++ L + Sbjct: 993 SIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS 1052 Query: 1252 FPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVN 1311 P+ PL + LN G T + Q + NP TP ++ + Sbjct: 1053 PKPESTCPL-CKTELNIGSKDPPNFNTCTECKNQVCNLCGFNP----TPHLTEIQEWLCL 1107 Query: 1312 SGKQSNSGATKRASPSNSRRSSPGSSRKTTPSP-GRQNSKAPKLTLASQTNAALLQNVEL 1370 + + T+RA G RK P+P G + S P T +S A+ V+L Sbjct: 1108 NCQ------TQRAISGQL-----GDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKL 1156 Query: 1371 PRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLN-------VPQ 1423 + Q V A ++E KE+L+ V Sbjct: 1157 -------------------------VKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTT 1191 Query: 1424 DSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQS--KKDGQPSDPNKLPSVEENKNLVS 1481 D + S+ K++ + + P E K ++PE++ ++ +P K P+ E+K L+ Sbjct: 1192 DQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPT-PEDKKLLP 1250 Query: 1482 PAMREAPTS------------LSQLLDNSGAPNVT-------IKPPGLTDLEVTPPVVSG 1522 A AP + L+ AP K GL TP + Sbjct: 1251 EAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP--SGTPQSLPK 1308 Query: 1523 EDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS-R 1581 ED K I + +P E + S+ SS+ P P +S Sbjct: 1309 EDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTE-----KEDDKSDTSSSQQPKSPQGLSDT 1363 Query: 1582 PVSSSSISTPL-------PPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNA 1634 SS IS+ L P ++ + + S +S + P+ L + L STV+++ A Sbjct: 1364 GYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDL-AKLESTVLSILEA 1422 Query: 1635 GSKVMVSEGQSAAQSNARPQFITP 1658 + + E ++ +P ++P Sbjct: 1423 QASTLADE---KSEKKTQPHEVSP 1443 Score = 77.4 bits (189), Expect = 1e-13 Identities = 255/1264 (20%), Positives = 421/1264 (33%), Gaps = 212/1264 (16%) Query: 187 GGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPV 246 G +V S+ +P P QP +P +Q Q H P P QP Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQ--------------QPGHEKSQPGPAKPPAQPS 336 Query: 247 SVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPP-QQHQQQQPQGIRPQ 305 + + + QQ + Q + Q A+PP QQ ++P +P Sbjct: 337 GLTKPL---------AQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP- 386 Query: 306 FTAPTQVPVPPGWNQLPS---GALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPS 362 P + PPG + P+ G +PP Q A Q ++P P Sbjct: 387 --GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP---------- 434 Query: 363 LATVQTPSHPPPPYPFGSQQASQAHTNFPQMSN---PGQFTAP-QMKSLQGGPSRVPTPL 418 +TP P P +QQA T+ Q P Q P + Q GP++ P Sbjct: 435 -GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP-- 491 Query: 419 QQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNP--LPQGFQQPVSSPGR 476 QQP + K P+ P S + P QQ +PP P QQP SP + Sbjct: 492 QQPG-SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP--SPAK 548 Query: 477 NPMVQQGNVPPNFMVMQQ--QPPNQGPQSLHPGLGGMPKRLPPGFSAGQ--------ANP 526 P QQ P + + QPP P + P G+PK + P + + AN Sbjct: 549 -PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANF 607 Query: 527 NFMQGQVPSTTATTPGNSGAPQLQ-------ANQNVQHAGGQGAGP----PQNQMQ---- 571 N + +T + G + P L N ++ A G P PQ +++ Sbjct: 608 NTCT-ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666 Query: 572 -----VSHGPPNMMQPSL---MGIHGNMNNQQAGTSGVPQVNLSNMQGQPQ---QGPP-- 618 VS P Q S +++ P V + G P + PP Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726 Query: 619 ---SQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNP--PSQNL-GP 672 S+ + VPS+ Q M+ L+ P PS + Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786 Query: 673 SPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIM-----TNQMQGNKQQ 727 + ++ TPP + S + Q P + + P + + +I+ +++ +G KQ Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV 846 Query: 728 FNTQNQSNVMPGPAQIMRGPTPNMQ-----GNMVQFTGQMSGQML--PQQGPVNNSPSQV 780 Q + P AQ P P+ + +GQ + PQQ P S+ Sbjct: 847 DPVQKKEE--PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRR 904 Query: 781 MGIQ-GQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGN 839 + G + P P Q+ SQ +S PH Q+ G Sbjct: 905 FSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS--TAGQPGPHSQSGPG- 961 Query: 840 SASGNHFSGHGMSFNAPFSGAP--------NGNQMSCGQNPGFPVNKDVTLTSPLLVNLL 891 AP AP G S GQ P P K + + Sbjct: 962 ---------------APMKQAPAPSQPPTSQGPPKSTGQAPPAPA-KSIPVKKETKAPAA 1005 Query: 892 QSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQP----P 947 + K+ T +KK PP K S P LE++ +P P Sbjct: 1006 EKLEPKAEQAPTVKRTET-----EKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060 Query: 948 LPGEQGINLDNSGPKLPEFSNRPP---------GYPSQP----------VEQRPLQQMPP 988 L + +N+ + P P F+ G+ P + + + + Sbjct: 1061 LCKTE-LNIGSKDP--PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISG 1117 Query: 989 QL--MQHVAPPPQPPQQQPQP---QLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDP 1043 QL ++ + P P P+ P P + Q+ PP ++Q+Q+ + +++++ Sbjct: 1118 QLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEK-- 1175 Query: 1044 KSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNT 1103 V+ +S PP + + +++ + + P P+++++ +P Sbjct: 1176 --VKETLSMEKIPPMVTTDQKQEESKLEKDKASALQ-------EKKPLPEEKKL-IPEEE 1225 Query: 1104 PLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMM 1163 + S +K + +E P L LPEA S P ++ Q Q+ Sbjct: 1226 KIRSEEKKPLLEEKKPTPEDKKL-----LPEAKTS-------APEEQKHDLLKSQVQIAE 1273 Query: 1164 TGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP---NVAAPTQTSRPKTPNRASPRPY 1220 + +P + +G P Q + LPS P + T +P+ P A P Sbjct: 1274 EKLEGRVAPKTVQEGKQP-QTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQV 1332 Query: 1221 YP----QTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLN 1276 P + T S+ SP+ L S G I+ L P+L ++ L Sbjct: 1333 EPGKEKTEKEDDKSDTSSSQQPKSPQGL--SDTGYSSDGISSSLGEIPSLIPTDEKDILK 1390 Query: 1277 PTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGS 1336 + Q S +PS+ A ++ L + + ++ + K+ P P Sbjct: 1391 GLKKDSFSQESS--PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKD 1448 Query: 1337 SRKT 1340 KT Sbjct: 1449 QEKT 1452 Score = 50.4 bits (119), Expect = 2e-05 Identities = 153/742 (20%), Positives = 237/742 (31%), Gaps = 134/742 (18%) Query: 152 PMGAGNSVRMEAGF--PMASGPGIIRMNNPATVMIPPG-GNVSSSMMAPGPNPELQPRTP 208 P+G + G P + PG P + PPG G + P P Q TP Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPG------PKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418 Query: 209 RPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQ 268 +P +Q + P+ + P P+Q Q P P Q + Sbjct: 419 KPLAQQPGLQS------------PAKAPGPTKTPVQ------QPGPGKIPAQQAGPGKTS 460 Query: 269 QQQQQQQQQQQQ--------QQQQQLQARPPQQHQQQQPQGIRPQFTAPT-QVPVPPGWN 319 QQ + Q QQ PPQQ +P +P T P Q P P + Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520 Query: 320 QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQ-TPSHPPPPYPF 378 G+ +PP Q +A Q P P Q +P T P PP P Sbjct: 521 PQQPGSTKPPSQQPGSAKPSAQQ-----PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPS 575 Query: 379 GSQQASQA--------------HTNFPQMSNPGQFTAPQ--MKSLQG-GPSRVPTPL--- 418 Q SQ + P+ +N T Q + SL G P+ T + Sbjct: 576 AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEW 635 Query: 419 -----QQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSS 473 Q A PSS Q + T + P+P Q +P + S Sbjct: 636 LCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS 695 Query: 474 PGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQV 533 P ++ PP +LH K+ P S + P + V Sbjct: 696 KAPEP--------------KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP-KEPSV 740 Query: 534 PSTTATTPGNSGAPQ----------LQANQNVQHAGGQGAGPPQNQMQVSHGPP---NMM 580 PS P P+ L ++ + + Q+Q + PP + Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800 Query: 581 QPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQ-QIVPSQGQMVQQQ 639 +PS + +P+ S+ + GP S+ G Q V + + + Q Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIPR-PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ 859 Query: 640 GTLNPQNPMILSRAQLMPQGQMMVNPPSQNLG---PSPQRMTPPKQMLSQ----QGPQMM 692 ++P+ A+ MP+G P G P+PQ+ P++ + G Sbjct: 860 TKMSPK-----PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD 914 Query: 693 APHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQ 752 AP +Q PQ + +T ++ G +Q SN++ Q P P+ Q Sbjct: 915 APKSQPTTPQ------------ETVTGKLFGFGASIFSQ-ASNLISTAGQ----PGPHSQ 957 Query: 753 GNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDV 812 M P Q P + P + G PP P+ + + A A Sbjct: 958 SGP---GAPMKQAPAPSQPPTSQGPPKSTG-----QAPPAPAKSIPVKKETKAPAAEKLE 1009 Query: 813 SLSQMMPDVSIQQTNMVPPHVQ 834 ++ P V +T PP ++ Sbjct: 1010 PKAEQAPTVKRTETEKKPPPIK 1031 Score = 45.4 bits (106), Expect = 6e-04 Identities = 103/461 (22%), Positives = 159/461 (34%), Gaps = 80/461 (17%) Query: 1477 KNLVSPAMREAPTS-LSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQ 1535 K V PA E+P+ Q LD+S P + +PP P + L K+ T + Sbjct: 68 KGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPD-------PGRPAQPGLSKSRTTDTFR 120 Query: 1536 DLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPN 1595 S K P S P + L S +L E + + +P +S + S++S+ + Sbjct: 121 --SEQKLPGRS---PSTISLKESKSRTDLKE--EHKSSMMPGFLSEVNALSAVSSVVNKF 173 Query: 1596 QITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQF 1655 ++ + + T + ++ P Q + Q Sbjct: 174 NPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQD 233 Query: 1656 ITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPP 1715 TP I+S QP I + P T + GP PQ A +P Sbjct: 234 GTPKSISSQ---------QPEKIKSQPPGTGKPIQ-------GPTQTPQT---DHAKLPL 274 Query: 1716 NALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQV 1775 +S P QT + ++ + LPSP S PP+QQ P P Sbjct: 275 QRDASRP----QTKQADIVRGESVKPSLPSP---------SKPPIQQPTPGKPPAQQPGH 321 Query: 1776 NTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKV 1835 S P +Q + + P L PG+ P ++K + +G K + Sbjct: 322 EKSQPGPAKPPAQPSGLTKP-LAQQPGTVKPPVQPPGTTKPPAQ--PLGP---AKPPAQQ 375 Query: 1836 TGSLEKGEEQYGADGETEGQGLDTT-----APGLMGTEQLST----------ELDSKTPT 1880 TGS + EQ G + G+ T P T+Q+ T + +K P Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435 Query: 1881 P-------PAPTLLKMTSSPVGPGTASA---GPSLPGGALP 1911 P P P K+ + GPG SA GP+ P LP Sbjct: 436 PTKTPVQQPGPG--KIPAQQAGPGKTSAQQTGPTKPPSQLP 474 Score = 44.7 bits (104), Expect = 0.001 Identities = 78/334 (23%), Positives = 122/334 (36%), Gaps = 52/334 (15%) Query: 971 PGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP--PPPSQPQSQQQQQ 1028 P S P + RP + + PPP PP P P P P PPP+ P+ + Sbjct: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPK 2440 Query: 1029 QQQQM-------------MMMLMMQQDPKSVRLPVSQ--NVHPPRGPLNPDS-------- 1065 ++ + + L +S LPV++ PP P P S Sbjct: 2441 KKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFT 2500 Query: 1066 -----QRMPMQQSGSVPVM-VSLQGPASVPPSPDKQRMPMPVNTPL-GSNSRKMVYQESP 1118 + P+ +P + + Q P + P P + + L S K+ SP Sbjct: 2501 HRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSP 2560 Query: 1119 QNP---SSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPS-PLS 1174 +P SSP + PS PG P + + +Q + + P PS L Sbjct: 2561 LSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSA------SQAITSWPLGSPSKDLV 2614 Query: 1175 ATQGATPQQPPVNSLP---SSHGHHFPNVAAPTQTSRPKT-PNRASPRPYYPQTPNNRPP 1230 + + PPV ++ SS + + A T ++ P T P+ P T + Sbjct: 2615 SVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAP----TSVTQFL 2670 Query: 1231 STEPSEISLSPERLNASIAGLFPPQINIPLPPRP 1264 +TE S+ +S R A GL I+I +PP P Sbjct: 2671 TTEVSKTEVSATRSTAPSVGL--SSISITIPPEP 2702 Score = 38.1 bits (87), Expect = 0.090 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%) Query: 261 QQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQ 320 Q++++Q Q +Q+ QQQ Q +Q+Q Q HQQ + Q IR + Q P Sbjct: 3271 QEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIY----QYNYDPSGTA 3326 Query: 321 LPSGALQPPPAQGSLGTMTANQGW 344 P + +G + +Q W Sbjct: 3327 SPQTTTEQAILEGQYAALEGSQFW 3350 Score = 32.3 bits (72), Expect = 4.9 Identities = 30/112 (26%), Positives = 38/112 (33%), Gaps = 14/112 (12%) Query: 208 PRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQ 267 PR A Q++ I Q+ L PP P + P P QQ Sbjct: 3856 PRTAPQTEFSQ------FIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHF 3909 Query: 268 QQQQQQQQQQQQQQQQQQLQA-----RPPQQHQQQQPQGIRPQFTAPTQVPV 314 +QQ QQ Q Q QA PQ PQ P + P+Q+ V Sbjct: 3910 EQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQ---PSYQLPSQMMV 3958 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 87.8 bits (216), Expect = 1e-16 Identities = 310/1521 (20%), Positives = 498/1521 (32%), Gaps = 325/1521 (21%) Query: 227 QQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQ------ 280 ++Q P G + PP P + +Q P P LQQ + QQ ++ + Q Sbjct: 198 KEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDP-LQQDGTPKSISSQQPEKIKSQPPGTGK 256 Query: 281 ------QQQQQLQARPPQQHQQQQPQ----------GIRPQFTAPTQVPVPPGWNQLPSG 324 Q Q A+ P Q +PQ ++P +P++ P+ Q P+ Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPI-----QQPTP 311 Query: 325 ALQPPPAQGSLGTMTANQGWKKAPL-PGPMQQQLQARPSLATVQTPSHP-----PPPYPF 378 PPAQ G + G K P P + + L +P TV+ P P PP P Sbjct: 312 G--KPPAQ-QPGHEKSQPGPAKPPAQPSGLTKPLAQQP--GTVKPPVQPPGTTKPPAQPL 366 Query: 379 GSQQ--ASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQ 436 G + A Q + P PG P L QP K+PA Q Sbjct: 367 GPAKPPAQQTGSEKPSSEQPG-----------------PKALAQPPGVGKTPA------Q 403 Query: 437 QGSPASSPTVNQTQQQMG-PRPPQNNPLPQGFQQPVSSPG--RNPMVQQGNVPPNFMVMQ 493 Q PA PT QQ+G P+P P G Q P +PG + P+ Q G P Q Sbjct: 404 QPGPAKPPT-----QQVGTPKPLAQQP---GLQSPAKAPGPTKTPVQQPG--PGKIPAQQ 453 Query: 494 QQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQ 553 P Q P PP G A P Q PG + P Q Sbjct: 454 AGPGKTSAQQTGP-------TKPPSQLPGPAKPPPQQ----------PGPAKPPPQQPG- 495 Query: 554 NVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQP 613 A PP Q + PP P+ + QQ G++ P + + Sbjct: 496 --------SAKPPSQQPGSTKPPPQQPGPA------KPSPQQPGSTKPPSQQPGSAKPSA 541 Query: 614 QQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPS 673 QQ P++ Q P V Q G+ P P +S P + PPSQ L + Sbjct: 542 QQPSPAK-PSAQQSTKP-----VSQTGSGKPLQPPTVS-----PSAK---QPPSQGLPKT 587 Query: 674 PQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQV--LLQQNPMIEQIMTNQMQGNKQQFNTQ 731 + ++L + A N Q V L NP + Q Sbjct: 588 ICPLCNTTELLLHVPEK--ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRA 645 Query: 732 NQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPP 791 ++ P P+ P P ++ V T +S + PQ P SP + + + + P Sbjct: 646 LGGDLAPVPS----SPQPKLKTAPVTTTSAVS-KSSPQ--PQQTSPKKDAAPKQDLSKAP 698 Query: 792 GPS--PHMAQQ---HGDPATTANNDV---SLSQMMP----------------DVSIQQTN 827 P P + +Q HG P+ A SLS+ P D +Q Sbjct: 699 EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPK 758 Query: 828 MVPPHVQAMQGNSASGN-HFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPV--NKDVTLTS 884 MV P + +SA+ + A P S + FP K S Sbjct: 759 MVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDS 818 Query: 885 PLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEAD 944 + H G +++ P +KK KK ++ PD +P + + Sbjct: 819 KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS-PKPDAKPMP-KGSP 876 Query: 945 QPPLP---GEQGINLDNSGPKLPEFSNR-----------PPGYPSQPVEQRPLQ------ 984 PP P Q + PK E S R P P+ P E + Sbjct: 877 TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936 Query: 985 QMPPQLMQHVAPPPQP-PQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDP 1043 + Q ++ QP P Q P P +Q P P P SQ Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP----------------- 979 Query: 1044 KSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPS-----PDKQRMP 1098 P S PP ++ +P+++ P L+ A P+ +K+ P Sbjct: 980 -----PKSTGQAPP-----APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029 Query: 1099 MPVNTPLGSNSRKMV----YQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHV 1154 + + L + +K V ++SP+ S+ PL + +E P N + Sbjct: 1030 IKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK---------TELNIGSKDPPNFNTCT 1080 Query: 1155 VLPQNQLMMTGPKPGP----------------SPLSATQGATPQQPPVNSLPSSHGHHFP 1198 + G P P +S G + PP S P + Sbjct: 1081 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKA-----S 1135 Query: 1199 NVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINI 1258 + PT++S KT A P + TE ++ L + S+ Sbjct: 1136 PMPVPTESSSQKT---AVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSME--------- 1183 Query: 1259 PLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNS 1318 +PP ++ ++ L A+ + P+ KL + Sbjct: 1184 KIPPMVTTDQKQEESKLEKDKASALQEKK----------PLPEEKKLIPEEEKIRSEEKK 1233 Query: 1319 GATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSP 1378 + P+ + ++ + P + + ++ +A + L+ P+ V Sbjct: 1234 PLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEK----LEGRVAPKTVQEGK 1289 Query: 1379 TPLAN-PPVPGSFPNNSGLNPQNSTVSV--------AAVGGVVEDNKESLNVPQD-SDCQ 1428 P +P P + +T ++ A VE KE D SD Sbjct: 1290 QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTS 1349 Query: 1429 NSQSRK------------EQVNIELKAVPA------QEVKMVVPEDQSKKDGQPSDPNKL 1470 +SQ K + ++ L +P+ +++ + +D ++ PS P+ L Sbjct: 1350 SSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDL 1409 Query: 1471 PSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPV-------VSGE 1523 +E ++S +A T + + P+ + P D E T + +S E Sbjct: 1410 AKLE--STVLSILEAQASTLADEKSEKKTQPH-EVSPEQPKDQEKTQSLSETLEITISEE 1466 Query: 1524 DLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPV 1583 ++K+ S +E ++ ++ SS H E SE ++ P S Sbjct: 1467 EIKE-----------SQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEE 1515 Query: 1584 SSSSISTPLPPNQITVFVTSN 1604 SS S ++P+P + V S+ Sbjct: 1516 SSESENSPVPQRKRRTSVGSS 1536 Score = 87.4 bits (215), Expect = 1e-16 Identities = 322/1521 (21%), Positives = 503/1521 (33%), Gaps = 290/1521 (19%) Query: 649 ILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQ 708 ++ + Q P+G ++ PP Q PPK + QQGP G+ LQ Sbjct: 195 VVQKEQGKPEG--IIKPPLQQ--------QPPKPIPKQQGP-------------GRDPLQ 231 Query: 709 QNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLP 768 Q+ + I + Q + K Q PG + ++GPT Q + + Q P Sbjct: 232 QDGTPKSISSQQPEKIKSQ---------PPGTGKPIQGPTQTPQTDHAKLPLQRDASR-P 281 Query: 769 QQG-----------PVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQM 817 Q P SPS+ Q +PP P + PA L++ Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341 Query: 818 MPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVN 877 + QQ V P VQ P A Q + + P Sbjct: 342 LA----QQPGTVKPPVQPPGTTKPPAQ-----------PLGPAKPPAQQTGSEKPSSEQP 386 Query: 878 KDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNS------QQDLN 931 L P V T A +P KPP ++ + Q L Sbjct: 387 GPKALAQPPGVG------------------KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428 Query: 932 TPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLM 991 +P P + Q P PG+ I +GP + S + G P++P Q P PP Sbjct: 429 SPAKAPGPTKTPVQQPGPGK--IPAQQAGPG--KTSAQQTG-PTKPPSQLPGPAKPPPQQ 483 Query: 992 QHVAPPPQPPQQQPQPQLPQQQQP----PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVR 1047 P +PP QQP P QQP PPP QP + QQ P S + Sbjct: 484 PG---PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ------------PGSTK 528 Query: 1048 LPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQG----PASVPPS---PDKQRMPMP 1100 P SQ + S P Q + PV + G P +V PS P Q +P Sbjct: 529 -PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT 587 Query: 1101 VNTPLGSNSRKMVYQESP--------------------QNPSSSPLAEM----ASLPEAS 1136 + PL + + +++ NP + + E + A Sbjct: 588 I-CPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRAL 646 Query: 1137 GSEAPSVPGGPN--------NMPSHVVLPQNQLMMTGPKPGPSPLSATQGA--TPQQPPV 1186 G + VP P S V Q T PK +P A + PP+ Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706 Query: 1187 NSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNA 1246 P+ HG P P+ + + P P P E S+ E+ A Sbjct: 707 VKQPTLHGSPSAKAKQP-----PEADSLSKPAP--------------PKEPSVPSEQDKA 747 Query: 1247 SIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLD 1306 +A P Q + P D + T K PS+ + + T K D Sbjct: 748 PVADDKPKQPKMVKPTT-------DLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLKTD 798 Query: 1307 SVVVNSGKQSNSGATKRASPSNSRR-SSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALL 1365 S QS ++ SP +S+ P S K PG P Q + Sbjct: 799 SA---KPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG------PSSESKGQKQVDPV 849 Query: 1366 QNVELPR--NVLVSPTPLANPPVPGSFPNNSGLNP---QNSTVSVAAVGGVVEDNKESLN 1420 Q E P+ +SP P A P GS P G P Q + + + SLN Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPKGS-PTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908 Query: 1421 VPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLV 1480 + +D SQ Q + K + GQP ++ K Sbjct: 909 LGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ-- 966 Query: 1481 SPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSS 1540 +PA + PTS AP K + P E KA PT++ + Sbjct: 967 APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLE--PKAEQAPTVKRTETE 1024 Query: 1541 KEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSS--SISTPLPPNQIT 1598 K+P P + S P+ + + + + S P + P+ + +I + PPN T Sbjct: 1025 KKP------PPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078 Query: 1599 VFVTSN-----------PITTSANTSAALPTHLQSAL---MSTVVTMPNAGSKVMVSEGQ 1644 N P T L Q A+ + + MP A S S Sbjct: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP 1138 Query: 1645 SAAQSNARPQFITP-VFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIP 1703 +S+++ + P V + +V ++ + T + +PP V Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVT-------- 1190 Query: 1704 QNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQV 1763 + + L A +Q +PL + P + P++ P + Sbjct: 1191 -----TDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPED 1245 Query: 1764 KELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKI 1823 K+L P+ TSA P Q ++ + + R +P + +GK K+ Sbjct: 1246 KKL-----LPEAKTSA-----PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKM 1295 Query: 1824 GQI------LLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELD-S 1876 + L K K T ++ K + Q + D PG TE+ + D S Sbjct: 1296 EGLPSGTPQSLPKEDDKTTKTI-KEQPQPPCTAKP-----DQVEPGKEKTEKEDDKSDTS 1349 Query: 1877 KTPTPPAPTLLKMTSSPVGPGTASAG--PSLPGGALPTSVRSIVTTLVPSELI-SAVPTT 1933 + P +P L T ++S G PSL +PT + I+ L + P++ Sbjct: 1350 SSQQPKSPQGLSDTGYSSDGISSSLGEIPSL----IPTDEKDILKGLKKDSFSQESSPSS 1405 Query: 1934 KSNHGGIAS------ESLAGGLVEEKVGSHPELLP-SIAPSQNLVSKETSTTALQASVAR 1986 S+ + S E+ A L +EK S + P ++P Q ++T + + + Sbjct: 1406 PSDLAKLESTVLSILEAQASTLADEK--SEKKTQPHEVSPEQPKDQEKTQSLSETLEITI 1463 Query: 1987 PELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPT-----VASESVENGHRKRSSRP 2041 E E+ KE E+ K +++S+ + P+ SE V++ +R Sbjct: 1464 SEEEI------------KESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYD 1511 Query: 2042 ASASSSTKDITSAVQSKRRKS 2062 + SS + + Q KRR S Sbjct: 1512 SVEESSESENSPVPQRKRRTS 1532 Score = 84.7 bits (208), Expect = 8e-16 Identities = 321/1524 (21%), Positives = 510/1524 (33%), Gaps = 284/1524 (18%) Query: 308 APTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQ 367 +P+ +P G + L + M+ QG K +P + PS+ Q Sbjct: 31 SPSHTAIPAGM-EADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAES----PSMHRKQ 85 Query: 368 T--PSHPP-----PPYPF-----GSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP 415 SHPP PP P G ++ T + PG+ +P SL+ SR Sbjct: 86 ELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR--SPSTISLKESKSR-- 141 Query: 416 TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVS--- 472 T L++ H ++ P S A S VN+ NP S Sbjct: 142 TDLKEEHKSSMMPGFL--SEVNALSAVSSVVNKF-----------NPFDLISDSEASQEE 188 Query: 473 SPGRNPMVQQGNVPPNFMV---MQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFM 529 + + +VQ+ P ++ +QQQPP P+ PG + + P + Q P + Sbjct: 189 TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQ-QPEKI 247 Query: 530 QGQVPSTTATTPGNSGAPQLQ-ANQNVQHAGGQGAGPPQNQMQVSHGP---PNMMQPSLM 585 + Q P T G + PQ A +Q + P Q + G P++ PS Sbjct: 248 KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR---PQTKQADIVRGESVKPSLPSPSKP 304 Query: 586 GIHGNMNNQQAGTSGVPQVNLSNMQGQPQQG-PPSQLMGMHQQIVPSQGQM---VQQQGT 641 I QQ P + + QP PP+Q G+ + + G + VQ GT Sbjct: 305 PI------QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT 358 Query: 642 -------LNPQNPMILSRAQLMPQGQM-----MVNPP------SQNLGPSP---QRMTPP 680 L P P P + + PP +Q GP+ Q++ P Sbjct: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418 Query: 681 KQMLSQQGPQMMAPHNQMMGPQGQVLLQQNP-MIEQIMTNQMQGNKQQFNTQNQSNVMPG 739 K + Q G Q A + GP + Q P I + + QQ + +PG Sbjct: 419 KPLAQQPGLQSPA---KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475 Query: 740 PAQI---MRGPT--PNMQGNMVQFTGQMSGQMLP---QQGPVNNSP---------SQVMG 782 PA+ GP P Q + Q G P Q GP SP SQ G Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535 Query: 783 IQGQVLRPPGPSPHMAQQHGDPATTANNDVSL-------------SQMMPDVSIQQTNM- 828 + P P+ AQQ P + + L SQ +P N Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595 Query: 829 -----VPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQN----------PG 873 VP S G + N + ++C P Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655 Query: 874 FPVNK----DVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQD 929 P K VT TS + + Q ++ KQ+ + A +PKK P K+ Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715 Query: 930 LNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPP---GYPSQPVEQRPLQQM 986 + +P + +P P E P +P ++ P P QP +P + Sbjct: 716 PSAKAKQPPEADSLSKPAPPKE---------PSVPSEQDKAPVADDKPKQPKMVKPTTDL 766 Query: 987 PPQLMQHVAPPPQPPQQQPQPQLPQQQQPP--PPSQPQSQQQQQQQQQMMMMLMMQQDPK 1044 P P + Q Q ++ PP S SQ +++ D K Sbjct: 767 VSS--SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-----DSK 819 Query: 1045 SVRLPVSQN---VHP-PRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMP 1100 ++ P S + HP P Q P+Q+ + + P PD + PMP Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEE-----PKKAQTKMSPKPDAK--PMP 872 Query: 1101 VNTPLGSNSRKMVYQESP---QNPSSSPLAEMASLPEASGSEAP---------SVPGGPN 1148 +P R Q P Q+P + SL S ++AP +V G Sbjct: 873 KGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932 Query: 1149 NMPSHVVLPQNQLMMTGPKPGPSPLSA-----TQGATPQQPPVNSLPSSHGHHFP----- 1198 + + + L+ T +PGP S Q P QPP + P P Sbjct: 933 GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992 Query: 1199 NVAAPTQTSRP---KTPNRASPRPYYPQTPNNR--PPSTEPSEISLSPER--LNASIAGL 1251 ++ +T P K +A P +T + PP + ++ P++ L + Sbjct: 993 SIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS 1052 Query: 1252 FPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVN 1311 P+ PL + LN G T + Q + NP TP ++ + Sbjct: 1053 PKPESTCPL-CKTELNIGSKDPPNFNTCTECKNQVCNLCGFNP----TPHLTEIQEWLCL 1107 Query: 1312 SGKQSNSGATKRASPSNSRRSSPGSSRKTTPSP-GRQNSKAPKLTLASQTNAALLQNVEL 1370 + + T+RA G RK P+P G + S P T +S A+ V+L Sbjct: 1108 NCQ------TQRAISGQL-----GDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKL 1156 Query: 1371 PRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLN-------VPQ 1423 + Q V A ++E KE+L+ V Sbjct: 1157 -------------------------VKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTT 1191 Query: 1424 DSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQS--KKDGQPSDPNKLPSVEENKNLVS 1481 D + S+ K++ + + P E K ++PE++ ++ +P K P+ E+K L+ Sbjct: 1192 DQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPT-PEDKKLLP 1250 Query: 1482 PAMREAPTS------------LSQLLDNSGAPNVT-------IKPPGLTDLEVTPPVVSG 1522 A AP + L+ AP K GL TP + Sbjct: 1251 EAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP--SGTPQSLPK 1308 Query: 1523 EDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS-R 1581 ED K I + +P E + S+ SS+ P P +S Sbjct: 1309 EDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTE-----KEDDKSDTSSSQQPKSPQGLSDT 1363 Query: 1582 PVSSSSISTPL-------PPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNA 1634 SS IS+ L P ++ + + S +S + P+ L + L STV+++ A Sbjct: 1364 GYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDL-AKLESTVLSILEA 1422 Query: 1635 GSKVMVSEGQSAAQSNARPQFITP 1658 + + E ++ +P ++P Sbjct: 1423 QASTLADE---KSEKKTQPHEVSP 1443 Score = 77.4 bits (189), Expect = 1e-13 Identities = 255/1264 (20%), Positives = 421/1264 (33%), Gaps = 212/1264 (16%) Query: 187 GGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPV 246 G +V S+ +P P QP +P +Q Q H P P QP Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQ--------------QPGHEKSQPGPAKPPAQPS 336 Query: 247 SVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPP-QQHQQQQPQGIRPQ 305 + + + QQ + Q + Q A+PP QQ ++P +P Sbjct: 337 GLTKPL---------AQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP- 386 Query: 306 FTAPTQVPVPPGWNQLPS---GALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPS 362 P + PPG + P+ G +PP Q A Q ++P P Sbjct: 387 --GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP---------- 434 Query: 363 LATVQTPSHPPPPYPFGSQQASQAHTNFPQMSN---PGQFTAP-QMKSLQGGPSRVPTPL 418 +TP P P +QQA T+ Q P Q P + Q GP++ P Sbjct: 435 -GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP-- 491 Query: 419 QQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNP--LPQGFQQPVSSPGR 476 QQP + K P+ P S + P QQ +PP P QQP SP + Sbjct: 492 QQPG-SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP--SPAK 548 Query: 477 NPMVQQGNVPPNFMVMQQ--QPPNQGPQSLHPGLGGMPKRLPPGFSAGQ--------ANP 526 P QQ P + + QPP P + P G+PK + P + + AN Sbjct: 549 -PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANF 607 Query: 527 NFMQGQVPSTTATTPGNSGAPQLQ-------ANQNVQHAGGQGAGP----PQNQMQ---- 571 N + +T + G + P L N ++ A G P PQ +++ Sbjct: 608 NTCT-ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666 Query: 572 -----VSHGPPNMMQPSL---MGIHGNMNNQQAGTSGVPQVNLSNMQGQPQ---QGPP-- 618 VS P Q S +++ P V + G P + PP Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726 Query: 619 ---SQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNP--PSQNL-GP 672 S+ + VPS+ Q M+ L+ P PS + Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786 Query: 673 SPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIM-----TNQMQGNKQQ 727 + ++ TPP + S + Q P + + P + + +I+ +++ +G KQ Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV 846 Query: 728 FNTQNQSNVMPGPAQIMRGPTPNMQ-----GNMVQFTGQMSGQML--PQQGPVNNSPSQV 780 Q + P AQ P P+ + +GQ + PQQ P S+ Sbjct: 847 DPVQKKEE--PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRR 904 Query: 781 MGIQ-GQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGN 839 + G + P P Q+ SQ +S PH Q+ G Sbjct: 905 FSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS--TAGQPGPHSQSGPG- 961 Query: 840 SASGNHFSGHGMSFNAPFSGAP--------NGNQMSCGQNPGFPVNKDVTLTSPLLVNLL 891 AP AP G S GQ P P K + + Sbjct: 962 ---------------APMKQAPAPSQPPTSQGPPKSTGQAPPAPA-KSIPVKKETKAPAA 1005 Query: 892 QSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQP----P 947 + K+ T +KK PP K S P LE++ +P P Sbjct: 1006 EKLEPKAEQAPTVKRTET-----EKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060 Query: 948 LPGEQGINLDNSGPKLPEFSNRPP---------GYPSQP----------VEQRPLQQMPP 988 L + +N+ + P P F+ G+ P + + + + Sbjct: 1061 LCKTE-LNIGSKDP--PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISG 1117 Query: 989 QL--MQHVAPPPQPPQQQPQP---QLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDP 1043 QL ++ + P P P+ P P + Q+ PP ++Q+Q+ + +++++ Sbjct: 1118 QLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEK-- 1175 Query: 1044 KSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNT 1103 V+ +S PP + + +++ + + P P+++++ +P Sbjct: 1176 --VKETLSMEKIPPMVTTDQKQEESKLEKDKASALQ-------EKKPLPEEKKL-IPEEE 1225 Query: 1104 PLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMM 1163 + S +K + +E P L LPEA S P ++ Q Q+ Sbjct: 1226 KIRSEEKKPLLEEKKPTPEDKKL-----LPEAKTS-------APEEQKHDLLKSQVQIAE 1273 Query: 1164 TGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP---NVAAPTQTSRPKTPNRASPRPY 1220 + +P + +G P Q + LPS P + T +P+ P A P Sbjct: 1274 EKLEGRVAPKTVQEGKQP-QTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQV 1332 Query: 1221 YP----QTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLN 1276 P + T S+ SP+ L S G I+ L P+L ++ L Sbjct: 1333 EPGKEKTEKEDDKSDTSSSQQPKSPQGL--SDTGYSSDGISSSLGEIPSLIPTDEKDILK 1390 Query: 1277 PTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGS 1336 + Q S +PS+ A ++ L + + ++ + K+ P P Sbjct: 1391 GLKKDSFSQESS--PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKD 1448 Query: 1337 SRKT 1340 KT Sbjct: 1449 QEKT 1452 Score = 50.4 bits (119), Expect = 2e-05 Identities = 153/742 (20%), Positives = 237/742 (31%), Gaps = 134/742 (18%) Query: 152 PMGAGNSVRMEAGF--PMASGPGIIRMNNPATVMIPPG-GNVSSSMMAPGPNPELQPRTP 208 P+G + G P + PG P + PPG G + P P Q TP Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPG------PKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418 Query: 209 RPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQ 268 +P +Q + P+ + P P+Q Q P P Q + Sbjct: 419 KPLAQQPGLQS------------PAKAPGPTKTPVQ------QPGPGKIPAQQAGPGKTS 460 Query: 269 QQQQQQQQQQQQ--------QQQQQLQARPPQQHQQQQPQGIRPQFTAPT-QVPVPPGWN 319 QQ + Q QQ PPQQ +P +P T P Q P P + Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520 Query: 320 QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQ-TPSHPPPPYPF 378 G+ +PP Q +A Q P P Q +P T P PP P Sbjct: 521 PQQPGSTKPPSQQPGSAKPSAQQ-----PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPS 575 Query: 379 GSQQASQA--------------HTNFPQMSNPGQFTAPQ--MKSLQG-GPSRVPTPL--- 418 Q SQ + P+ +N T Q + SL G P+ T + Sbjct: 576 AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEW 635 Query: 419 -----QQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSS 473 Q A PSS Q + T + P+P Q +P + S Sbjct: 636 LCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS 695 Query: 474 PGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQV 533 P ++ PP +LH K+ P S + P + V Sbjct: 696 KAPEP--------------KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP-KEPSV 740 Query: 534 PSTTATTPGNSGAPQ----------LQANQNVQHAGGQGAGPPQNQMQVSHGPP---NMM 580 PS P P+ L ++ + + Q+Q + PP + Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800 Query: 581 QPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQ-QIVPSQGQMVQQQ 639 +PS + +P+ S+ + GP S+ G Q V + + + Q Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIPR-PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ 859 Query: 640 GTLNPQNPMILSRAQLMPQGQMMVNPPSQNLG---PSPQRMTPPKQMLSQ----QGPQMM 692 ++P+ A+ MP+G P G P+PQ+ P++ + G Sbjct: 860 TKMSPK-----PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD 914 Query: 693 APHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQ 752 AP +Q PQ + +T ++ G +Q SN++ Q P P+ Q Sbjct: 915 APKSQPTTPQ------------ETVTGKLFGFGASIFSQ-ASNLISTAGQ----PGPHSQ 957 Query: 753 GNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDV 812 M P Q P + P + G PP P+ + + A A Sbjct: 958 SGP---GAPMKQAPAPSQPPTSQGPPKSTG-----QAPPAPAKSIPVKKETKAPAAEKLE 1009 Query: 813 SLSQMMPDVSIQQTNMVPPHVQ 834 ++ P V +T PP ++ Sbjct: 1010 PKAEQAPTVKRTETEKKPPPIK 1031 Score = 45.4 bits (106), Expect = 6e-04 Identities = 103/461 (22%), Positives = 159/461 (34%), Gaps = 80/461 (17%) Query: 1477 KNLVSPAMREAPTS-LSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQ 1535 K V PA E+P+ Q LD+S P + +PP P + L K+ T + Sbjct: 68 KGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPD-------PGRPAQPGLSKSRTTDTFR 120 Query: 1536 DLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPN 1595 S K P S P + L S +L E + + +P +S + S++S+ + Sbjct: 121 --SEQKLPGRS---PSTISLKESKSRTDLKE--EHKSSMMPGFLSEVNALSAVSSVVNKF 173 Query: 1596 QITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQF 1655 ++ + + T + ++ P Q + Q Sbjct: 174 NPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQD 233 Query: 1656 ITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPP 1715 TP I+S QP I + P T + GP PQ A +P Sbjct: 234 GTPKSISSQ---------QPEKIKSQPPGTGKPIQ-------GPTQTPQT---DHAKLPL 274 Query: 1716 NALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQV 1775 +S P QT + ++ + LPSP S PP+QQ P P Sbjct: 275 QRDASRP----QTKQADIVRGESVKPSLPSP---------SKPPIQQPTPGKPPAQQPGH 321 Query: 1776 NTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKV 1835 S P +Q + + P L PG+ P ++K + +G K + Sbjct: 322 EKSQPGPAKPPAQPSGLTKP-LAQQPGTVKPPVQPPGTTKPPAQ--PLGP---AKPPAQQ 375 Query: 1836 TGSLEKGEEQYGADGETEGQGLDTT-----APGLMGTEQLST----------ELDSKTPT 1880 TGS + EQ G + G+ T P T+Q+ T + +K P Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435 Query: 1881 P-------PAPTLLKMTSSPVGPGTASA---GPSLPGGALP 1911 P P P K+ + GPG SA GP+ P LP Sbjct: 436 PTKTPVQQPGPG--KIPAQQAGPGKTSAQQTGPTKPPSQLP 474 Score = 44.7 bits (104), Expect = 0.001 Identities = 78/334 (23%), Positives = 122/334 (36%), Gaps = 52/334 (15%) Query: 971 PGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP--PPPSQPQSQQQQQ 1028 P S P + RP + + PPP PP P P P P PPP+ P+ + Sbjct: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPK 2440 Query: 1029 QQQQM-------------MMMLMMQQDPKSVRLPVSQ--NVHPPRGPLNPDS-------- 1065 ++ + + L +S LPV++ PP P P S Sbjct: 2441 KKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFT 2500 Query: 1066 -----QRMPMQQSGSVPVM-VSLQGPASVPPSPDKQRMPMPVNTPL-GSNSRKMVYQESP 1118 + P+ +P + + Q P + P P + + L S K+ SP Sbjct: 2501 HRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSP 2560 Query: 1119 QNP---SSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPS-PLS 1174 +P SSP + PS PG P + + +Q + + P PS L Sbjct: 2561 LSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSA------SQAITSWPLGSPSKDLV 2614 Query: 1175 ATQGATPQQPPVNSLP---SSHGHHFPNVAAPTQTSRPKT-PNRASPRPYYPQTPNNRPP 1230 + + PPV ++ SS + + A T ++ P T P+ P T + Sbjct: 2615 SVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAP----TSVTQFL 2670 Query: 1231 STEPSEISLSPERLNASIAGLFPPQINIPLPPRP 1264 +TE S+ +S R A GL I+I +PP P Sbjct: 2671 TTEVSKTEVSATRSTAPSVGL--SSISITIPPEP 2702 Score = 38.1 bits (87), Expect = 0.090 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 4/84 (4%) Query: 261 QQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQ 320 Q++++Q Q +Q+ QQQ Q +Q+Q Q HQQ + Q IR + Q P Sbjct: 3271 QEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIY----QYNYDPSGTA 3326 Query: 321 LPSGALQPPPAQGSLGTMTANQGW 344 P + +G + +Q W Sbjct: 3327 SPQTTTEQAILEGQYAALEGSQFW 3350 Score = 32.3 bits (72), Expect = 4.9 Identities = 30/112 (26%), Positives = 38/112 (33%), Gaps = 14/112 (12%) Query: 208 PRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQ 267 PR A Q++ I Q+ L PP P + P P QQ Sbjct: 3856 PRTAPQTEFSQ------FIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHF 3909 Query: 268 QQQQQQQQQQQQQQQQQQLQA-----RPPQQHQQQQPQGIRPQFTAPTQVPV 314 +QQ QQ Q Q QA PQ PQ P + P+Q+ V Sbjct: 3910 EQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQ---PSYQLPSQMMV 3958 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 87.0 bits (214), Expect = 2e-16 Identities = 234/1008 (23%), Positives = 346/1008 (34%), Gaps = 225/1008 (22%) Query: 1007 PQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDS- 1065 P+ P +PPPP P + + ++ R P+++ G P+S Sbjct: 27 PRPPGSPRPPPPVTPAA------------LRVLGAAGAVGRKPLAERAGGIGGATIPESA 74 Query: 1066 -QRMPMQQSGSVPVMVSLQGPASVPPS--------PDKQRMPMPVNT-----------PL 1105 + P + +G+ S + PAS PP+ P K P PV++ PL Sbjct: 75 PRAGPTRSAGT-----SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129 Query: 1106 GSNSRKMVYQ---------ESPQNPSSS--------------PLAEMASLPEASGSE--- 1139 G ++ + E+P+ + S P MA A+G+E Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189 Query: 1140 ---APSV-PGGPNNMPSHVVLPQNQLMMTGPKPG-------------PSPLSATQGATPQ 1182 APS P P P V ++ T P P P+ S + ATP Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249 Query: 1183 QPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQ-TPNNRPPSTEPSEISLSP 1241 P S PS+ G AP S+PK + RP PQ TP + + +S SP Sbjct: 250 SSPARSGPSARG----TPRAPAHPSQPKPKGLQALRP--PQVTPPRKDAAPALGPLSSSP 303 Query: 1242 ---ERLNASIAGLFPPQIN------IPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTM 1292 + + A PP N LPP P L +P+ AP +L Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS-------APPSLQT 356 Query: 1293 NPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAP 1352 PS ATP + S+ + S T P S S + PSP +S Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQT--IPPIQVPHSLTSPSLQAPPSPLALSSLQA 414 Query: 1353 KLTLASQTNAALLQNVEL-PRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGV 1411 +L S T A + + PR S L +P P S P +S Sbjct: 415 TTSLGSPTLQATHSFLTMSPRQTQAS---LTSPSRPASTPPDS----------------- 454 Query: 1412 VEDNKESLNVPQDSDCQNSQS-RKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKL 1470 + L++P Q S S ++ L P Q + + S P + Sbjct: 455 -PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLA----SHSPQAPLSSLIM 509 Query: 1471 PSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASV 1530 P +E +L P+++ P SL+ P L +L P ++ L+ AS Sbjct: 510 PPLETQSSLAPPSLQTPPASLT--------------TPPLENL----PSLAPPPLQTASA 551 Query: 1531 IPTLQDLSSSKEPSN-SLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSIS 1589 T L + P+ L P S + PE + P PP ++ P S Sbjct: 552 PLTTPHLETPPCPAPCPLQAPPSP---LTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608 Query: 1590 TPL-----PPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQ 1644 PL PP Q + P+ + A+ P L P A + + V Q Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPP------LSPLATPSPQAPNALAVHLLQ 662 Query: 1645 SAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQ 1704 + P P S P++ P +P T PPS+A PL +P Sbjct: 663 APFSPPPSPPVQAPF-------------SPPASPPVSPSATPPSQAPPSLA-APPLQVPP 708 Query: 1705 NIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVK 1764 S PP + S++P P Q PL A P+Q+P P S P+ PS P +V Sbjct: 709 ----SPPASPPMSPSATPPP--QAPPPLA----APPLQVPPSPPASPPMSPSATPPPRVP 758 Query: 1765 ELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIG 1824 P A+P + PS ++ +SPL P + +P + G Sbjct: 759 ---PLLAAPPLQVP------PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG 809 Query: 1825 QILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPA- 1883 Q + + L Q AP ++ L P+PPA Sbjct: 810 QAPFSPSASLPMSPLATPPPQ---------------APPVLAAPLLQV-----PPSPPAS 849 Query: 1884 PTLLKMTSSPV-GPGTASAGP----SLPGGALPTSVRSIVTTLVPSEL 1926 PTL P GP T+ +GP +L G P RS +TL +L Sbjct: 850 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 897 Score = 84.7 bits (208), Expect = 8e-16 Identities = 228/953 (23%), Positives = 348/953 (36%), Gaps = 128/953 (13%) Query: 1086 ASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGS-EAPSVP 1144 ++ PSP +R P SR + S P SSP S P A G+ AP+ P Sbjct: 216 STTEPSPAARRRPSAGGGLQRPASRSL---SSSATPLSSPAR---SGPSARGTPRAPAHP 269 Query: 1145 GGPNNMPSHVVLPQNQLMMTGPK----PGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV 1200 P + P +T P+ P PLS++ ATP + P N Sbjct: 270 SQPKPKGLQALRPPQ---VTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD---NA 323 Query: 1201 AAPTQTSRPKTPNRASPRPYYPQTPNNRPPS--TEPSEISLSPERLNASIAGLFPPQINI 1258 A P + P +P A+P P P +P+ PPS T PS + P + PP + Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPSPS-APPSLQTLPSPPATPPSQA--------PPSMTT 374 Query: 1259 P-LPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNP----SNFATPQTHKLDSVVVNSG 1313 P + P+L Q + T ++ PS L ++ ++ +P S + S Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434 Query: 1314 KQSNSGATKRASPSNSRRSSPGSSRKTT--PSPGRQNSKAPKLT-LASQTNAALLQNVEL 1370 +Q+ + T + P+++ SP + SP Q S +P ++ L+S LQ + Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL-- 492 Query: 1371 PRNVLVSPTPLA--NPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQ 1428 + L S +P A + + S L P + A++ +N SL P Q Sbjct: 493 --SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP---LQ 547 Query: 1429 NSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAP 1488 + + ++E PA P P P E ++ +P + P Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQA-----------PPSPLTTPPPETPSSIATPPPQAPP 596 Query: 1489 TSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLN 1548 S L +P ++ P T PP ++ L+ P LS PS Sbjct: 597 ALASPPLQGLPSPPLS---PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA- 652 Query: 1549 LPHSNELCSSLVHPELSEVSSNV--APSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPI 1606 N L L+ S S AP PP S PVS S+ PP+Q + + P+ Sbjct: 653 ---PNALAVHLLQAPFSPPPSPPVQAPFSPPA-SPPVSPSAT----PPSQAPPSLAAPPL 704 Query: 1607 TTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQ----SNARPQFITPVFIN 1662 + A+ P SA P A + V A+ S P + P+ Sbjct: 705 QVPPSPPASPPMS-PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL-- 761 Query: 1663 SSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAV--VGPLHIPQNIKFSSAPVPPNA-LS 1719 ++ +QV S P+++P +PL PP++A + L P AP P+A L Sbjct: 762 AAPPLQVPP-SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 820 Query: 1720 SSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDE--ASPQVNT 1777 SP P VL++ V PSPP + + P PP PD + P++ Sbjct: 821 MSPLATPPPQAPPVLAAPLLQVP-PSPPASPTLQAPRRPPTP-----GPDTSVSGPRLTL 874 Query: 1778 SADQNTLP---SSQSTTMVSPLLTNSPGSSGNR----RSPVSSSKGKGKVDKIGQILLTK 1830 + P S S+T+ P L S+ + R S +G L Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA- 933 Query: 1831 ACKKVTGSLEKGEEQYGADGETEGQGL---DTTAPGLMGTEQLSTELDSKTP--TPPAPT 1885 AC S +G A G L T PG + L T +++ P PAP Sbjct: 934 ACHPAAWS--RGPAPPLAFRGAPGAPLPWPPATGPG--SADGLCTIYETEGPESATPAPG 989 Query: 1886 LLKMTSSP----------VGPGTASAGP------SLPGGALPTSV--RSIVTTLVPSELI 1927 L SP G G +S P LP GAL SV + TL+ + Sbjct: 990 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE 1049 Query: 1928 SAVPTTKSNHGGIASESLAGG----LVEEKVGSHPELLPSIAPSQNLVSKETS 1976 A + GG + GG L + ++G ELL + S+ ++ TS Sbjct: 1050 GAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTS 1102 Score = 83.2 bits (204), Expect = 2e-15 Identities = 166/720 (23%), Positives = 252/720 (35%), Gaps = 104/720 (14%) Query: 755 MVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQ--VLRPPGPSPHMAQQHGDPATTANNDV 812 + + G + G +P+ P P++ G + RPP A G+ A A N Sbjct: 58 LAERAGGIGGATIPESAP-RAGPTRSAGTSSRNPASRPP------ASGRGERAPPAKNTS 110 Query: 813 SLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGA--PNGNQMSCGQ 870 P + T P +G S G + AP A + + G Sbjct: 111 PGPVSSPGRASGTTR---PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP 167 Query: 871 NPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDL 930 PG P SP + +S + G+ + P + PRK +S + Sbjct: 168 TPGTP--------SPAMAR--RSRAAGTEVGLPRPAPSARPRPPTEG--PRKSVSSASEH 215 Query: 931 NTPDTRPAGLEEADQP---PLPGEQGINLDNSGPKLPEFSN-------RPPGYPSQPVEQ 980 +T + PA P + ++ + P S R P +PSQP + Sbjct: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275 Query: 981 -----RPLQQMPPQ--LMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQM 1033 RP Q PP+ + P P P P + + PPP + Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335 Query: 1034 MMMLMMQQDPKSVRLPVSQNVHP-----PRGPLNPDSQRMPMQQSGSVPVMVSLQGPASV 1088 + + P S P S P P P PMQ S+ + +Q P S+ Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395 Query: 1089 PPSPDKQRMPMPV-------NTPLGSNSRKMVYQ-------------ESPQNPSSS---- 1124 SP Q P P+ T LGS + + + SP P+S+ Sbjct: 396 -TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454 Query: 1125 -PLAEMASLP-----EASGSEAPSVPGGP---------NNMPSH-VVLPQNQLMMTGPKP 1168 PL SLP + S S A S P +++ SH P + L+M + Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514 Query: 1169 GPS---PLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYY-PQT 1224 S P T A+ PP+ +LPS +AP T +TP +P P P + Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS 574 Query: 1225 PNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQ--QGLNPTTLKA 1282 P PP PS I+ P + ++A PP +P PP L Q L L+A Sbjct: 575 PLTTPPPETPSSIATPPPQAPPALAS--PPLQGLPSPPLSPLATPPPQAPPXLALPPLQA 632 Query: 1283 IGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTP 1342 P++ ++P +PQ +V + S + +P + S P S T P Sbjct: 633 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 692 Query: 1343 SPGRQNSKAPKLTLASQTNAA--LLQNVELPRNVLVSPTPLANPP--VPGSFPNNSGLNP 1398 S + AP L + A+ + + P +P PLA PP VP S P + ++P Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ---APPPLAAPPLQVPPSPPASPPMSP 749 Score = 76.6 bits (187), Expect = 2e-13 Identities = 221/1023 (21%), Positives = 333/1023 (32%), Gaps = 204/1023 (19%) Query: 423 LTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQN-NPLPQGFQQPVSSPGRNPMVQ 481 + NK + + + A +P + + PRPP P + GR P+ + Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60 Query: 482 Q-GNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANP---NFMQGQVPS-- 535 + G + + + P GP P PP G+ P N G V S Sbjct: 61 RAGGI--GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118 Query: 536 --TTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQM------QVSHGP-PNMMQPSLMG 586 + T PG G L+ + A G+ P+ + + GP P P++ Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA- 177 Query: 587 IHGNMNNQQAGTS-GVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQ 645 ++ AGT G+P+ S P +GP + + T P Sbjct: 178 ----RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS------------ASEHSTTEP- 220 Query: 646 NPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQM-LSQQGPQMMAPHNQMMGPQGQ 704 +P R G + P S++L S ++ P + S +G H P+G Sbjct: 221 SPAARRRPSA---GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277 Query: 705 VLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGP--TPNMQGNMVQFTGQM 762 L+ P + T + + P + P TP+ G + Sbjct: 278 QALRP-PQV----------------TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP 320 Query: 763 SGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPS-PHMAQQHGDPATTANNDVSLSQMMPDV 821 P + SP + L PP PS P Q P T + S P + Sbjct: 321 DNAATPLPATLPPSPPLATPLP---LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377 Query: 822 SIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVT 881 + P +Q S +P AP Sbjct: 378 QAPPSLQTIPPIQVPH--------------SLTSPSLQAP-------------------- 403 Query: 882 LTSPLLVNLLQSDISAG-------HFGVNNKQNNTNANKPKKKKPPRKKKNS---QQDLN 931 SPL ++ LQ+ S G H + T A+ +P +S Q L+ Sbjct: 404 -PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462 Query: 932 TPDTRP--AGLEEADQP---PL---PGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPL 983 P + P L A P PL P + +L + P+ P S P +Q P Sbjct: 463 LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPS 522 Query: 984 QQMPP--------QLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMM 1035 Q PP + + +APPP P P + PP P+ Q + Sbjct: 523 LQTPPASLTTPPLENLPSLAPPPLQTASAPLTT-PHLETPPCPAPCPLQAPPSP-----L 576 Query: 1036 MLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQ 1095 + P S+ P PP+ P P P+Q S P+ P + PP Sbjct: 577 TTPPPETPSSIATP------PPQAP--PALASPPLQGLPSPPL-----SPLATPPPQAPP 623 Query: 1096 RMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVV 1155 + +P PL Q P P+S PL+ +A+ PS P PN + H Sbjct: 624 XLALP---PL---------QAPPSPPASPPLSPLAT---------PS-PQAPNALAVH-- 659 Query: 1156 LPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRA 1215 L+ P PSP + P PPV+ + P++AAP P P A Sbjct: 660 -----LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP--A 712 Query: 1216 SPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPR-PNLNRGFDQQG 1274 SP P +P+ PP P ++ P ++ S P + PPR P L Sbjct: 713 SP----PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL-------- 760 Query: 1275 LNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSP 1334 L L+ P++L M+P PQ + S + +P + S P Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 820 Query: 1335 GSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLA--NPPVPGSFPN 1392 S T P AP L ++P + SPT A PP PG + Sbjct: 821 MSPLATPPPQAPPVLAAPLL--------------QVPPSPPASPTLQAPRRPPTPGPDTS 866 Query: 1393 NSG 1395 SG Sbjct: 867 VSG 869 Score = 70.9 bits (172), Expect = 1e-11 Identities = 200/915 (21%), Positives = 289/915 (31%), Gaps = 139/915 (15%) Query: 143 RSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPG-PNP 201 R+ GP+G +R+ A +A G P + G +S PG P+P Sbjct: 119 RASGTTRPGPLGQ-KGLRISAEETVARGKAT---EAPKRSALSAGARRDTSGPTPGTPSP 174 Query: 202 ELQPRT---------PRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQM 252 + R+ PRPA + P + S S A H +P R+ Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPT-------EGPRKSVSSASEHSTTEPSPAARRR 227 Query: 253 NPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGI---RPQFTAP 309 A + + + + R P Q +P+G+ RP P Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287 Query: 310 TQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATV--- 366 + P L S L P G+ PLP L P LAT Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT----LPPSPPLATPLPL 343 Query: 367 --QTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLT 424 +PS PP S A+ P M+ P P ++++ P +VP L P L Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP--PIQVPHSLTSPSLQ 401 Query: 425 NKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGN 484 + SS Q + SPT+ T + P Q Q ++SP R + Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT-------QASLTSPSR-----PAS 449 Query: 485 VPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNS 544 PP+ PP Q P SL P + L P S + Q S+ A S Sbjct: 450 TPPD------SPPLQAPLSL-PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLA-----S 497 Query: 545 GAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQV 604 +PQ + + P + Q S PP++ P A + P Sbjct: 498 HSPQAPLSSLIM---------PPLETQSSLAPPSLQTP------------PASLTTPPLE 536 Query: 605 NLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQ-----GTLNPQNPMILSRAQLMPQG 659 NL ++ P Q + L H + P Q T P+ P S A PQ Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS--SIATPPPQA 594 Query: 660 -QMMVNPPSQNLGPSP---QRMTPPKQMLSQQG-PQMMAPHNQMMGPQGQVLLQQNPMIE 714 + +PP Q L PSP TPP Q P + AP + P L +P Sbjct: 595 PPALASPPLQGL-PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653 Query: 715 QIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVN 774 + + Q+ P P+ ++ P F+ S + P P + Sbjct: 654 NALAVHLL----------QAPFSPPPSPPVQAP----------FSPPASPPVSPSATPPS 693 Query: 775 NSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQ 834 +P + QV P SP M+ P+ T P + VPP Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMS-----PSATPPPQAPPPLAAPPL------QVPPSPP 742 Query: 835 AMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNP--GFPVNKDVTLTSPLLVNLLQ 892 A S S AP P S +P P L +P L L Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802 Query: 893 SDIS---AGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLP 949 S F + + P + PP Q +P P L+ +PP P Sbjct: 803 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT-LQAPRRPPTP 861 Query: 950 GEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQ----QP 1005 G + SGP+L PG P P P L H + P++ Sbjct: 862 GP---DTSVSGPRLT--LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916 Query: 1006 QPQLPQQQQPPPPSQ 1020 P+ PPP ++ Sbjct: 917 GPEGGAAASPPPDAE 931 Score = 67.8 bits (164), Expect = 1e-10 Identities = 203/964 (21%), Positives = 296/964 (30%), Gaps = 147/964 (15%) Query: 324 GALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQA 383 G PP S G +++ PGP+ Q+ + TV P Sbjct: 100 GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG 159 Query: 384 SQAHTNFPQMSNPGQFTAPQMKSL--QGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPA 441 ++ T+ P P A + ++ + G R P P +P + P S SS + S Sbjct: 160 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR-PAPSARPRPPTEGPRKSVSSASEHSTT 218 Query: 442 S-SPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQG 500 SP + G + P+SSP R+ +G P QP +G Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT--PRAPAHPSQPKPKG 276 Query: 501 PQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGG 560 Q+L P P+ PP A A G + S+ TP SG A Sbjct: 277 LQALRP-----PQVTPPRKDAAPA-----LGPLSSSPLATPSPSGTKARPVPPPDNAATP 326 Query: 561 QGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQ 620 A P + + P + P ++ + + P +M P Q PPS Sbjct: 327 LPATLPPSPPLAT---PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSL 383 Query: 621 LMGMHQQIVPSQGQMVQQQGTLN-PQNPMILSRAQLMPQ-GQMMVNPPSQNLGPSPQR-- 676 Q I P Q +L P +P+ LS Q G + L SP++ Sbjct: 384 -----QTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438 Query: 677 --MTPPKQMLSQ--QGPQMMAPHNQMMGPQGQVLLQQ--NPMIEQIMTNQMQGNKQQFNT 730 +T P + S P + AP + P Q L +P+ + + +Q + Sbjct: 439 ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498 Query: 731 QNQ----SNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQ 786 Q S +MP P++Q T + LP P + Sbjct: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL-ENLPSLAPPPLQTASAPLTTPH 557 Query: 787 VLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHF 846 + PP P+P Q P TT + S P PP +Q + S Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP-LQGLPSPPLS---- 612 Query: 847 SGHGMSFNAPFSGAPNGNQMSCGQNP----GFPVNKDVTLTSP-----LLVNLLQSDISA 897 P AP + Q P P + SP L V+LLQ+ S Sbjct: 613 -----PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 667 Query: 898 GHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLD 957 PP + P + PA PP+ Sbjct: 668 ---------------------PP------SPPVQAPFSPPAS------PPV--------- 685 Query: 958 NSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQ--PPQQQPQPQLPQQQQP 1015 P S PP + P++ P P + PPPQ PP P Q+P Sbjct: 686 --SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743 Query: 1016 PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGS 1075 PP P + + + + LP+S PP P P + P Q+ Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP--PQAPPALATPPLQALP 801 Query: 1076 VPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1135 P S G A PS P+ P + P +P +SP + P Sbjct: 802 SP-PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860 Query: 1136 SGSE------------APSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQ------ 1177 G + AP P P+ PS ++GP SAT Sbjct: 861 PGPDTSVSGPRLTLALAPGPPPPPSRSPSST--------LSGPDLAGHSSSATSTPEELR 912 Query: 1178 --------GATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 GA PP L + H AA ++ P R +P P P P Sbjct: 913 GYDSGPEGGAAASPPPDAELAACH------PAAWSRGPAPPLAFRGAPGAPLPWPPATGP 966 Query: 1230 PSTE 1233 S + Sbjct: 967 GSAD 970 Score = 58.2 bits (139), Expect = 8e-08 Identities = 163/776 (21%), Positives = 272/776 (35%), Gaps = 122/776 (15%) Query: 1072 QSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMA- 1130 ++G+ + + P + P P P P TP + + PLAE A Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAA-----LRVLGAAGAVGRKPLAERAG 63 Query: 1131 -----SLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGP---KPGPSPLSATQGATPQ 1182 ++PE++ P+ G ++ P + P P P+S+ P Sbjct: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS-----PG 118 Query: 1183 QPPVNSLPSSHGHHFPNVAAPTQTSRPKT---PNRASPRPYYPQTPNNRPPSTEPSEISL 1239 + + P G ++A +R K P R++ + + P T PS Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT-PSPAMA 177 Query: 1240 SPERLNASIAGLFPPQINI-PLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFA 1298 R + GL P + P PP K++ A + T PS A Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPR-------------KSVSSASEHSTTEPSPAA 224 Query: 1299 TPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRK----TTPSP-GRQNSKAPK 1353 + + + + +S AT +SP+ S S+ G+ R + P P G Q + P+ Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284 Query: 1354 LTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVE 1413 +T + A L + SP+ PVP P ++ P +T+ + Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP---PPDNAATPLPATLPPSPPLAT-- 339 Query: 1414 DNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSV 1473 L P S + Q+ L + PA P + P +P + Sbjct: 340 --PLPLAPPSPSAPPSLQT--------LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI 389 Query: 1474 EENKNLVSPAMREAPTSLS----QLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKAS 1529 + +L SP+++ P+ L+ Q + G+P + LT S Sbjct: 390 QVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT----------------MS 433 Query: 1530 VIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMS----RPVSS 1585 T L+S P+++ P S L + L P + ++++P++ P+ S P+ + Sbjct: 434 PRQTQASLTSPSRPASTP--PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA 491 Query: 1586 -SSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQ 1644 SS+++ P ++ + T S+ +L T S + +P+ + Q Sbjct: 492 LSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL----Q 547 Query: 1645 SAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIP- 1703 +A+ P TP P P +PLTT P S+A P P Sbjct: 548 TASAPLTTPHLETPP----------CPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597 Query: 1704 -QNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLP-----SPPCTSSPVVP-- 1755 + P PP + ++P P Q L L P P SP T SP P Sbjct: 598 LASPPLQGLPSPPLSPLATPPP--QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655 Query: 1756 ----------SHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSP 1801 S PP V+ ASP V+ SA T PS ++ +P L P Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA---TPPSQAPPSLAAPPLQVPP 708 Score = 44.3 bits (103), Expect = 0.001 Identities = 104/445 (23%), Positives = 140/445 (31%), Gaps = 74/445 (16%) Query: 149 MNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTP 208 + P S ++A F + P + P + PP + P P P P +P Sbjct: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS-QAPPSLAAPPLQVPPSP-PASPPMSP 718 Query: 209 RPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANF--PQLQQQQQQ 266 A PL + Q PS +PP M P + P P LQ Sbjct: 719 SATPPPQAPPPLAAP---PLQVPPSPPASPP---MSPSATPPPRVPPLLAAPPLQVPPSP 772 Query: 267 QQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGAL 326 + Q L A PP Q P P Q P P + LP L Sbjct: 773 PASLPMSPLAKPPPQAPPAL-ATPPLQALPSPPASF------PGQAPFSPSAS-LPMSPL 824 Query: 327 QPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQA 386 PP Q L P+ Q + P+ T+Q P PP P P S Sbjct: 825 ATPPPQAP------------PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS------ 866 Query: 387 HTNFPQMSNPGQFTAPQMKSLQGGPSRVP-TPLQQPHLT--NKSPASSPSSFQ------Q 437 +S P + T PSR P + L P L + S S+P + + Sbjct: 867 ------VSGP-RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919 Query: 438 GSPASSPTVNQTQQQMGPRPPQNNPLPQ-GFQQPVSSPGRNPMVQQGNVPPNFMVMQQQP 496 G A+SP + P P P F+ +P P + + Sbjct: 920 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE-- 977 Query: 497 PNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQN-- 554 +GP+S P G + PG S G+A G S+ + G L A Q Sbjct: 978 -TEGPESATPAPGALDPGPSPGTSGGKAAAG--AGAGASSRSPKQARLGELPLGALQASV 1034 Query: 555 VQH--------------AGGQGAGP 565 VQH AGG G GP Sbjct: 1035 VQHLLSRTLLLAAAEGAAGGSGGGP 1059 Score = 31.6 bits (70), Expect = 8.4 Identities = 69/335 (20%), Positives = 110/335 (32%), Gaps = 54/335 (16%) Query: 1719 SSSPAPNIQTGRPLVLSSRA--TPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVN 1776 +S P P + + SRA T V LP P ++ P P+ P + V Sbjct: 164 TSGPTPGTPSPA-MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA---------- 212 Query: 1777 TSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVT 1836 S STT SP P + G + P S S L+ + ++ Sbjct: 213 ---------SEHSTTEPSPAARRRPSAGGGLQRPASRS-------------LSSSATPLS 250 Query: 1837 GSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGP 1896 G G T + P G + L + AP L ++SSP+ Sbjct: 251 SPARSGPSARG----TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306 Query: 1897 GTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGS 1956 + S + P + + TL PS + A P + A SL + + S Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPL-ATPLPLAPPSPSAPPSL------QTLPS 359 Query: 1957 HPELLPSIAPSQNLVSKETSTTALQA--------SVARPELEVNAAIVSGQSSEPKEIVE 2008 P PS AP + +LQ S+ P L+ + ++ S + + Sbjct: 360 PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419 Query: 2009 KSKIPGRRNSRTEEPTVASESVENGHRKRSSRPAS 2043 + + T P S+ + R S+ P S Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454 >gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] Length = 1499 Score = 86.3 bits (212), Expect = 3e-16 Identities = 264/1249 (21%), Positives = 403/1249 (32%), Gaps = 268/1249 (21%) Query: 163 AGFPMASGPGIIRMNNPAT----VMIPPGGNVSSSMMAPGPNPELQPRT--------PRP 210 AG P + P + PA +PP G S PN T P Sbjct: 296 AGTPQSQPPPLPPPPPPAPGSAPPALPPEGPPEDSSQDLAPNSVGAASTGGGTGGTHPNT 355 Query: 211 ASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQ 270 + + A +PL G PS + P N Q + L ++Q + +++ Sbjct: 356 PTATTANNPLPPG------GDPSSAPGPALLGEAAAPGNGQRSLVGSEGLSKEQLEHRER 409 Query: 271 QQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPP 330 Q + ++ + + P + P G + P Q P PP QPP Sbjct: 410 SLQTLRDIERLLLRSGETEP----FLKGPPGGAGEGGPPAQAPPPPQ---------QPPT 456 Query: 331 AQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNF 390 A S G KK P+Q + SL H P +P G Q + Sbjct: 457 APPS--------GLKK--YEEPLQSMISQTQSLGGPPL-EHEVPGHPPGGDMGQQMNMMI 505 Query: 391 PQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQ 450 ++ P+ + + LQ+ + K P Sbjct: 506 QRLGQDS--LTPEQVAWR--------KLQEEYYEEKRRKEEQIGLHGSRPLQDMMGMGGM 555 Query: 451 QQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGG 510 GP PP ++ + + + R PM Q M ++ PP GP+ G Sbjct: 556 MVRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDP-----MQLRGGPPFPGPR-----FPG 605 Query: 511 MPKRLPPGFSAGQANP-----NFMQGQVPSTTATTPG--NSGAPQLQANQNVQHAGGQGA 563 + PGF Q+ P N MQ V T G P A + + GGQG Sbjct: 606 NQIQRVPGFGGMQSMPMEVPMNAMQRPVRPGMGWTEDLPPMGGPSNFAQNTMPYPGGQGE 665 Query: 564 GPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMG 623 + +++ L+ + G +G G Q ++M Sbjct: 666 A---ERFMTPRVREELLRHQLLEKRSMGMQRPLGMAG---------SGMGQSMEMERMMQ 713 Query: 624 MHQQIVPSQ--GQMVQQQGTLNPQNPMILS--RAQLMP----QGQMMVNPP--------- 666 H+Q+ P+ GQM +G M R L P G V+PP Sbjct: 714 AHRQMDPAMFPGQMAGGEGLAGTPMGMEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMN 773 Query: 667 -----SQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQM 721 + N+ + Q MTP +QML Q +M P +MGPQG + + Q + M Sbjct: 774 MNVNMNMNMNLNVQ-MTPQQQMLMSQ--KMRGP-GDLMGPQGLSPEEMARVRAQNSSGVM 829 Query: 722 QGNKQ-----QFNTQNQSNVM--PGPAQIMR---GPTPNM----QGNMVQF---TGQMSG 764 G ++ QF Q Q GP Q M G T +M Q +M T ++S Sbjct: 830 GGPQKMLMPSQFPNQGQQGFSGGQGPYQAMSQDMGNTQDMFSPDQSSMPMSNVGTTRLSH 889 Query: 765 QMLPQQGPVNNSPSQVMGIQGQVL-RPPGPSPHMAQQHGDPATTANNDVSLSQM-MPDVS 822 LP P +N P V + L R P Q G P +LSQ+ P V+ Sbjct: 890 MPLP---PASNPPGTVHSAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVT 946 Query: 823 IQQTNMVPPHVQAMQGNSASGN--------HFSGHGMSFNAPFSGAPNG--NQMSCGQNP 872 N+ P + S N G +S +P +G+P+ + +P Sbjct: 947 SPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLGSSLSVRSP-TGSPSRLKSPSMAVPSP 1005 Query: 873 GFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNT 932 G+ + + SP + Q + N + T +N + PP ++S Sbjct: 1006 GWVASPKTAMPSPGVSQNKQPPL-------NMNSSTTLSNMEQGTLPPSGPRSSSSA--P 1056 Query: 933 PDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQ 992 P P+GL P LP F++ P PSQ PL M Q+ + Sbjct: 1057 PANPPSGL------------------MNPSLP-FTSSPDPTPSQ----NPLSLMMTQMSK 1093 Query: 993 HVAPPPQP-----------PQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQ 1041 + P P + P P PPPP Q QM + Q Sbjct: 1094 YAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQMHLNSAAAQ 1153 Query: 1042 DPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPV 1101 P + LP Q PL S + P ++ PSP Sbjct: 1154 SPMGMNLPGQQ-------PL-------------------SHEPPPAMLPSP--------- 1178 Query: 1102 NTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNM--PSHVVLPQN 1159 TPLGSN + P + + P++ + VP M P + P Sbjct: 1179 -TPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHG 1237 Query: 1160 QLMMTGPKPG--------PSPLSATQGATPQQPPVNSLPSSH----------GHHFP--- 1198 + TG G PS ++ P QPP P H G +P Sbjct: 1238 AMAPTGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQQHLMGKAMAGRMGDAYPPGV 1297 Query: 1199 --------------NVAAPTQTSRPK--------TPNRASPRPYYPQTPNNRPPSTEPSE 1236 V PT T P+ + +S Y+P++ N P + P+ Sbjct: 1298 LPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNL 1357 Query: 1237 ISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQ 1285 ++ + + A PP LP + + RG + +P + +G+ Sbjct: 1358 HLMNLQNMMAEQTPSRPPN----LPGQQGVQRGLNMSMCHPGQMSLLGR 1402 Score = 81.3 bits (199), Expect = 9e-15 Identities = 134/546 (24%), Positives = 186/546 (34%), Gaps = 106/546 (19%) Query: 219 PLLSGLHIQQQSHPSGSLAPPHHPMQ--PVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQ 276 P LS +H + PS +L P P Q P+ P PQ+ + + Sbjct: 935 PTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLGSSLSVRSPTGSPSR 994 Query: 277 QQQQQQQ----------QQLQARPPQQHQQQQPQGIRPQFTAPT--QVPVPPGWNQLPSG 324 + + P +Q P + T Q +PP + S Sbjct: 995 LKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSS 1054 Query: 325 ALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQ---------ARPS--------LATVQ 367 A PPA G M + + +P P P Q L A PS + T+ Sbjct: 1055 A---PPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIA 1111 Query: 368 T---------PSHPPPPYPFGS------QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPS 412 T P PPPP P GS Q SQ H N +P P + L P Sbjct: 1112 TSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPP 1171 Query: 413 RV----PTPLQQP---HLTNKSPASSPSSFQQGSPASSPTVNQ------TQQQMGPRPPQ 459 PTPL H + P + +P ++N + QM P PP+ Sbjct: 1172 PAMLPSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPR 1231 Query: 460 NNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPG--------LGGM 511 P G P G P +QQ + P + + PNQ P + P G M Sbjct: 1232 LQQ-PHGAMAPTGGGGGGPGLQQ-HYPSGMALPPEDLPNQPPGPMPPQQHLMGKAMAGRM 1289 Query: 512 PKRLPPGFSAGQAN----PNFMQGQVPSTTATTPGNSGA--PQLQANQNVQHAGGQGAGP 565 PPG G A+ P + P+ T + P + + +Q+ P Sbjct: 1290 GDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQP 1349 Query: 566 P------------QNQM--QVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQG 611 P QN M Q PPN+ P G+ +N Q++L G Sbjct: 1350 PKAQPPNLHLMNLQNMMAEQTPSRPPNL--PGQQGVQRGLNMSMCHPG---QMSLLGRTG 1404 Query: 612 -QPQQGPPSQLMGMHQQIV-PSQGQMVQQQGTLNPQNPM---ILSRA--QLMPQGQMMVN 664 PQQG G+HQ ++ P QG M QQ L Q + + S+ L PQG +M Sbjct: 1405 VPPQQGMVPH--GLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYSQPPHMLSPQGSLMGP 1462 Query: 665 PPSQNL 670 PP QNL Sbjct: 1463 PPQQNL 1468 Score = 76.3 bits (186), Expect = 3e-13 Identities = 252/1176 (21%), Positives = 384/1176 (32%), Gaps = 193/1176 (16%) Query: 440 PASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQ 499 P S+P+ Q Q P PP P +PG P PP P + Sbjct: 290 PLSTPSAGTPQSQPPPLPPP----------PPPAPGSAPPALPPEGPPEDSSQDLAPNSV 339 Query: 500 GPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAG 559 G S G GG P +A AN G PS +A P G N G Sbjct: 340 GAASTGGGTGGTHPNTP---TATTANNPLPPGGDPS-SAPGPALLGEAAAPGNGQRSLVG 395 Query: 560 GQGAGPPQ-----NQMQVSHGPPNMM------QPSLMGIHGNMNNQQAGTSGVPQVNLSN 608 +G Q +Q ++ +P L G G AG G P + Sbjct: 396 SEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGG-----AGEGGPP----AQ 446 Query: 609 MQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQM--MVNPP 666 PQQ P + G+ + P Q + Q Q P P+ P G M +N Sbjct: 447 APPPPQQPPTAPPSGLKKYEEPLQSMISQTQSLGGP--PLEHEVPGHPPGGDMGQQMNMM 504 Query: 667 SQNLGPSPQRMTPPK---QMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQG 723 Q LG +TP + + L ++ + + +G G LQ + +M ++G Sbjct: 505 IQRLG--QDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGSRPLQDMMGMGGMM---VRG 559 Query: 724 NKQQFNTQNQSNVMPGPAQIMRGPT----------------PNMQGNMVQFTGQMSG-QM 766 ++++ PG +RGP P GN +Q G Q Sbjct: 560 PPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRGGPPFPGPRFPGNQIQRVPGFGGMQS 619 Query: 767 LPQQGPVNNSPSQVM-GIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDV--SI 823 +P + P+N V G+ PP P Q+ P + M P V + Sbjct: 620 MPMEVPMNAMQRPVRPGMGWTEDLPPMGGPSNFAQNTMPYPGGQGEAE-RFMTPRVREEL 678 Query: 824 QQTNMVPPHVQAMQ---GNSASG--------NHFSGHGMSFNAPFSGAPNGNQMSCGQNP 872 + ++ MQ G + SG H A F G G + G Sbjct: 679 LRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMMQAHRQMDPAMFPGQMAGGEGLAGTPM 738 Query: 873 GFPVNKDVTLTSPLL----VNLLQSDISAGHFGVN-NKQNNTNANKPKKKKPPRKKKNSQ 927 G L SP + + + + G+ +N N N N N + P ++ SQ Sbjct: 739 GMEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQ 798 Query: 928 QDLNTPDTR-PAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVE-----QR 981 + D P GL + + + + P+ P +P+Q + Q Sbjct: 799 KMRGPGDLMGPQGLSPEEMARVRAQNSSGVMGG----PQKMLMPSQFPNQGQQGFSGGQG 854 Query: 982 PLQQMPPQL--MQHVAPPPQ---PPQQQPQPQLPQQQQPP---PPSQPQSQQQQ---QQQ 1030 P Q M + Q + P Q P +L PP PP S + ++ Sbjct: 855 PYQAMSQDMGNTQDMFSPDQSSMPMSNVGTTRLSHMPLPPASNPPGTVHSAPNRGLGRRP 914 Query: 1031 QQMMMMLMMQQDP--KSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASV 1088 + + + P ++ P VH P + + P S VP+ P++ Sbjct: 915 SDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPL------PSAN 968 Query: 1089 PPSPDKQRM----PMPVNTPLGSNSRKMVYQESPQNPS--SSPLAEMASLPEASGSEAPS 1142 PP P K + V +P GS SR + +P +SP M S P S ++ P Sbjct: 969 PPGPLKSPQVLGSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPS-PGVSQNKQP- 1026 Query: 1143 VPGGPNNMPSHVVL---PQNQLMMTGPKPGPS--PLSATQGATPQQPPVNSLPSSHGHHF 1197 P NM S L Q L +GP+ S P + G P S P Sbjct: 1027 ----PLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPSQN 1082 Query: 1198 PNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQIN 1257 P TQ S+ P S P Y +N + S+ L P+R L PP Sbjct: 1083 PLSLMMTQMSKYAMP---SSTPLY----HNAIKTIATSDDELLPDR------PLLPP--- 1126 Query: 1258 IPLPPR---PNLNRGFDQQ-------GLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDS 1307 P PP+ P ++ Q +P + GQ P + P+ +P T + Sbjct: 1127 -PPPPQGSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSP-TPLGSN 1184 Query: 1308 VVVNSGKQSNSGATKRASPSNSRRSSPG-------------SSRKTTPSPGRQNSKAPKL 1354 + ++ Q G P NS +PG SS + P P R + Sbjct: 1185 IPLHPNAQGTGG-----PPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAM 1239 Query: 1355 TLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVED 1414 P + + P L N P PG P PQ + A G + + Sbjct: 1240 APTGGGGGGPGLQQHYPSGMALPPEDLPNQP-PGPMP------PQQHLMGKAMAGRMGDA 1292 Query: 1415 NKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVE 1474 + +P + N E + +P ++ ++P + +PS + Sbjct: 1293 YPPGV-LPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSE------KPSSTLQYFPKS 1345 Query: 1475 ENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGL 1510 EN+ P + P L N A +PP L Sbjct: 1346 ENQ----PPKAQPPNLHLMNLQNMMAEQTPSRPPNL 1377 Score = 75.1 bits (183), Expect = 7e-13 Identities = 190/848 (22%), Positives = 264/848 (31%), Gaps = 155/848 (18%) Query: 234 GSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQ 293 G L+PP V+ M P N Q QQQ Q P Sbjct: 747 GLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDL 806 Query: 294 HQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPP--PAQGSLGTMTANQGWKKAPLPG 351 PQG+ P+ A + G P L P P QG G G Sbjct: 807 ---MGPQGLSPEEMARVRAQNSSGVMGGPQKMLMPSQFPNQGQQGFSGGQ---------G 854 Query: 352 PMQQQLQARPSLATVQTPSHPPPPYP-FGSQQASQAHTNFPQMSNP-GQFTAPQMKSLQG 409 P Q Q + + +P P G+ + S H P SNP G + + L Sbjct: 855 PYQAMSQDMGNTQDMFSPDQSSMPMSNVGTTRLS--HMPLPPASNPPGTVHSAPNRGLGR 912 Query: 410 GPSRVPTPLQQPHLTNKSPASSPSSFQQGSP-ASSPTVN----QTQQQMGPRPPQNNPLP 464 PS + + Q SP+ Q SP +SP+ N QT QM P P N P P Sbjct: 913 RPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGP 972 Query: 465 QGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQA 524 Q + S + + P P L +P PG+ A Sbjct: 973 LKSPQVLGSS-----------------LSVRSPTGSPSRLKSPSMAVPS---PGWVAS-- 1010 Query: 525 NPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGG---QGAGPPQNQMQVSHGPPNMMQ 581 P T +PG S Q N N QG PP S PP Sbjct: 1011 ---------PKTAMPSPGVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPA--- 1058 Query: 582 PSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMG-MHQQIVPSQGQMVQQQG 640 N +G S+ P Q P S +M M + +PS + Sbjct: 1059 -----------NPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYH--- 1104 Query: 641 TLNPQNPMILSRAQLMPQGQMMVNPPS-QNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMM 699 N + S +L+P ++ PP Q GP P + L+ Q Sbjct: 1105 --NAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQMHLNSAAAQ--------- 1153 Query: 700 GPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFT 759 P G L Q P+ + P PA + P+P G+ + Sbjct: 1154 SPMGMNLPGQQPLSHE----------------------PPPAML---PSPTPLGSNIPLH 1188 Query: 760 GQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMP 819 G GP NS G + P GP P S SQMMP Sbjct: 1189 PNAQGT----GGPPQNSMMMAPGGPDSLNAPCGPVP-----------------SSSQMMP 1227 Query: 820 DVSIQQTNMVPPHVQAMQGNSA-SGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNK 878 PP +Q G A +G G G+ + P SG + Q PG P+ Sbjct: 1228 ---------FPPRLQQPHGAMAPTGGGGGGPGLQQHYP-SGMALPPEDLPNQPPG-PMPP 1276 Query: 879 DVTLTSPLLVNLLQSDISAGHF-GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRP 937 L + + G GV + N+ ++ + P + + P +P Sbjct: 1277 QQHLMGKAMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRI-IPSEKP 1335 Query: 938 AGL-----EEADQPPLPGEQGINLDNSGPKLPEFS-NRPPGYPSQPVEQRPLQQMP--PQ 989 + + +QPP ++L N + E + +RPP P Q QR L P Sbjct: 1336 SSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLNMSMCHPG 1395 Query: 990 LMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLP 1049 M + PPQQ P Q PP +QQ +Q + + P + P Sbjct: 1396 QMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYSQPPHMLSP 1455 Query: 1050 VSQNVHPP 1057 + PP Sbjct: 1456 QGSLMGPP 1463 Score = 65.9 bits (159), Expect = 4e-10 Identities = 136/619 (21%), Positives = 205/619 (33%), Gaps = 130/619 (21%) Query: 131 GEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNV 190 G G ++ + Q+ ++V + PMG GN + M M MN V + P + Sbjct: 745 GRGLLSPPMGQSGLREV--DPPMGPGN-LNMNMNVNM-------NMNMNLNVQMTPQQQM 794 Query: 191 SSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNR 250 S GP + P+ P + + + SG + P + Sbjct: 795 LMSQKMRGPGDLMGPQGLSPEEMARV-----------RAQNSSGVMGGPQ---------K 834 Query: 251 QMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPT 310 + P+ FP QQ Q Q Q Q P Q G T + Sbjct: 835 MLMPSQFPNQGQQGFSGGQGPYQAMSQDMGNTQDMFS--PDQSSMPMSNVGT----TRLS 888 Query: 311 QVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPS 370 +P+PP N P G + P N+G + P + P + +++P+ Sbjct: 889 HMPLPPASN--PPGTVHSAP----------NRGLGRRPSDLTISINQMGSPGMGHLKSPT 936 Query: 371 HPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPAS 430 SQ H+ P +++P + +KS Q VP P P KSP Sbjct: 937 ------------LSQVHS--PLVTSP----SANLKSPQTPSQMVPLPSANPPGPLKSPQV 978 Query: 431 SPSSFQQGSPASSPTVNQTQQQMGPRP-----PQN-NPLP---QGFQQPVSSPGRNPM-- 479 SS SP SP+ ++ P P P+ P P Q Q P++ + Sbjct: 979 LGSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTTLSN 1038 Query: 480 VQQGNVPPNFMVMQQQPPNQGPQS--LHPGL------GGMPKRLPPGFSAGQANPNFMQG 531 ++QG +PP+ P P S ++P L P + P Q + M Sbjct: 1039 MEQGTLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPS 1098 Query: 532 QVP------STTATT----------------PGNSGAPQLQANQNVQHAGGQGAGPPQ-- 567 P T AT+ P SG + + H A P Sbjct: 1099 STPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQMHLNSAAAQSPMGM 1158 Query: 568 ---NQMQVSHGPPNMMQPSLMGIHGN--MNNQQAGTSGVPQVNLSNMQGQPQQ-GPPSQL 621 Q +SH PP M PS + N ++ GT G PQ ++ G P P Sbjct: 1159 NLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGP 1218 Query: 622 MGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPK 681 + Q++P ++ Q G + P G P Q PS M P Sbjct: 1219 VPSSSQMMPFPPRLQQPHGA-------------MAPTGGGGGGPGLQQHYPS--GMALPP 1263 Query: 682 QMLSQQGPQMMAPHNQMMG 700 + L Q P M P +MG Sbjct: 1264 EDLPNQPPGPMPPQQHLMG 1282 Score = 53.1 bits (126), Expect = 3e-06 Identities = 105/466 (22%), Positives = 146/466 (31%), Gaps = 106/466 (22%) Query: 139 LAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSM---M 195 ++QN+ + MN N ME G SGP R ++ A PP G ++ S+ Sbjct: 1020 VSQNKQPPLNMNSSTTLSN---MEQGTLPPSGP---RSSSSAPPANPPSGLMNPSLPFTS 1073 Query: 196 APGPNPELQPRTPRPASQSDAMDPLLSGLHIQ--QQSHPSGSLAPPHHPMQPVSVNRQMN 253 +P P P P + S P + L+ + S P P+ P Q + Sbjct: 1074 SPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGS 1133 Query: 254 PANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQ--------------HQQQQP 299 Q Q Q QQ L PP H Q Sbjct: 1134 GPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNAQG 1193 Query: 300 QGIRPQFT------APTQVPVPPGWNQLPSGALQ---PPPAQGSLGTMTANQGWKKAPLP 350 G PQ + P + P G +PS + PP Q G M G P Sbjct: 1194 TGGPPQNSMMMAPGGPDSLNAPCG--PVPSSSQMMPFPPRLQQPHGAMAPTGGGGGGP-- 1249 Query: 351 GPMQQQLQARPSLATVQTPSHPPPPYP-----FGSQQASQAHTNFPQMSNPGQFTAPQMK 405 +QQ + +L P+ PP P P G A + +P PG + Sbjct: 1250 -GLQQHYPSGMALPPEDLPNQPPGPMPPQQHLMGKAMAGRMGDAYPPGVLPGVASVLNDP 1308 Query: 406 SLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASS--------PTV------NQTQQ 451 L PT + + L+ P+ PSS Q P S P + N + Sbjct: 1309 ELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAE 1368 Query: 452 QMGPRPP--------------------------------QNNPLPQGFQQPVSSPGRNPM 479 Q RPP Q +P G Q V SP + M Sbjct: 1369 QTPSRPPNLPGQQGVQRGLNMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLM 1428 Query: 480 VQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQAN 525 QQ NFM+M+Q+ G+GG PP + Q + Sbjct: 1429 TQQ-----NFMLMKQR-----------GVGGEVYSQPPHMLSPQGS 1458 Score = 43.9 bits (102), Expect = 0.002 Identities = 55/202 (27%), Positives = 80/202 (39%), Gaps = 34/202 (16%) Query: 1044 KSVRLPVSQNVHP--PRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPV 1101 ++ +LP+S++ P P GP P R G G VP P Q + + Sbjct: 195 QTTQLPLSESSVPGAPHGP--PPGLRPDAPGGGG--------GGGGVPGKPPSQFVYV-F 243 Query: 1102 NTPLGSNSRKMVYQESPQNPSSSPLA-EMASLPEASGSEAPSVPGGPNNMPSHVV---LP 1157 T L + + + V Q + S LA ++P A +AP VP P +P P Sbjct: 244 TTHLANTAAEAVLQ----GRADSILAYHQQNVPRAKLDQAPKVPPTPEPLPLSTPSAGTP 299 Query: 1158 QNQLMMTGPKPGPSPLSATQGATPQQPPVNS----LPSSHGHHFPNVAAPTQTSRPKTPN 1213 Q+Q P P P+P SA P+ PP +S P+S G + T + P TP Sbjct: 300 QSQPPPLPPPPPPAPGSAPPALPPEGPPEDSSQDLAPNSVG--AASTGGGTGGTHPNTPT 357 Query: 1214 RASPRPYYPQTPNNRPPSTEPS 1235 + N PP +PS Sbjct: 358 ATTAN-------NPLPPGGDPS 372 Score = 40.8 bits (94), Expect = 0.014 Identities = 47/184 (25%), Positives = 73/184 (39%), Gaps = 18/184 (9%) Query: 1619 HLQSALMSTV----VTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQ 1674 HL+S +S V VT P+A K + Q +A P P + S ++ GS Sbjct: 931 HLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANP----PGPLKSPQVL----GSS 982 Query: 1675 PSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVL 1734 S +P + S L PS+AV P + +P +S + P + L Sbjct: 983 LSV--RSPTGSPSRLKSPSMAVPSPGWVAS----PKTAMPSPGVSQNKQPPLNMNSSTTL 1036 Query: 1735 SSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVS 1794 S+ PS P +SS P++PP + P +SP S + +L +Q + Sbjct: 1037 SNMEQGTLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAM 1096 Query: 1795 PLLT 1798 P T Sbjct: 1097 PSST 1100 Score = 39.3 bits (90), Expect = 0.040 Identities = 44/144 (30%), Positives = 59/144 (40%), Gaps = 17/144 (11%) Query: 1673 SQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPL 1732 + PS +P T + + PS GPL PQ L SS + TG P Sbjct: 946 TSPSANLKSPQTPSQMVPLPSANPPGPLKSPQ------------VLGSSLSVRSPTGSPS 993 Query: 1733 VLSSRATPVQLPSPPCTSSP--VVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQST 1790 L S + V PSP +SP +PS P V Q K+ + S ++ +Q TLP S Sbjct: 994 RLKSPSMAV--PSPGWVASPKTAMPS-PGVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPR 1050 Query: 1791 TMVSPLLTNSPGSSGNRRSPVSSS 1814 + S N P N P +SS Sbjct: 1051 SSSSAPPANPPSGLMNPSLPFTSS 1074 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 85.1 bits (209), Expect = 6e-16 Identities = 219/1032 (21%), Positives = 359/1032 (34%), Gaps = 160/1032 (15%) Query: 1050 VSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNS 1109 V + PR L+P S P Q S + P P P+ +T + Sbjct: 1109 VHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSP 1168 Query: 1110 RKMVYQESPQNPSSSPLAEMASL----PEASG---SEAPSVPGGPNNMPSHVVLPQNQLM 1162 P + ++S +E +++ P+ASG S A S G + + P + + Sbjct: 1169 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 1228 Query: 1163 MTGP----KPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRP-KTPNRASP 1217 T P PG S S T ++P+ P P+S + T S+P T + SP Sbjct: 1229 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP 1288 Query: 1218 RPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNP 1277 P +E S S R ++ +FP + Sbjct: 1289 ------ASTTTPGLSEESTTVYSSSR-GSTETTVFP----------------------HS 1319 Query: 1278 TTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGS- 1336 TT G+ P+ P A+ T SG S A SP++++ P + Sbjct: 1320 TTTSVHGEEPTTFHSRP---ASTHTTLFTEDSTTSGLTEESTAFP-GSPASTQTGLPATL 1375 Query: 1337 -----SRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFP 1391 ++T P S KL+ A T + L+ R +SP+ +PGS P Sbjct: 1376 TTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSR---LSPSSTETTTLPGS-P 1431 Query: 1392 NNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKM 1451 L+ +++T + P+ D S PA Sbjct: 1432 TTPSLSEKSTTFYTS---------------PRSPDATLS--------------PATTTSS 1462 Query: 1452 VVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLT 1511 V E+ S QP + + A ++ T+ D S P + G T Sbjct: 1463 GVSEESSTSHSQPGSTH------------TTAFPDSTTT----SDLSQEPTTSHSSQGST 1506 Query: 1512 DLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNV 1571 + ++P + L + S SS + + LP + + S LV E S + + Sbjct: 1507 EATLSPGSTTASSLGQQST-----TFHSSPGDTETTLLP-DDTITSGLV--EASTPTHSS 1558 Query: 1572 APSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTM 1631 S+ ++ P SS+S + +S+ T S + A P + + S + Sbjct: 1559 TGSLHTTLT-PASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSST 1617 Query: 1632 PN---AGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSG 1688 P + S + + + ++ P + S V+ G +P+T P + +T + Sbjct: 1618 PTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVG-EPTTSPISSGSTETT 1676 Query: 1689 LMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLP-SPP 1747 +P S G ++ F S+P P+ + SPA +G V T P S Sbjct: 1677 ALPGSTTTAGLSE--KSTTFYSSPRSPDT-TLSPASTTSSG---VSEESTTSHSRPGSTH 1730 Query: 1748 CTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLT---NSPGSS 1804 T+ P + P V Q E +SP S D P S + + + P T +SPGS+ Sbjct: 1731 TTAFPGSTTMPGVSQ--ESTASHSSP---GSTDTTLSPGSTTASSLGPESTTFHSSPGST 1785 Query: 1805 GNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGL 1864 P +++ L +A V S G T QG TT Sbjct: 1786 ETTLLPDNTTASG----------LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 1835 Query: 1865 MGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSV-RSIVTTLVP 1923 ++ P PP T + S G+ S+ P+ A T++ RS +T V Sbjct: 1836 PSSK-------DTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVH 1888 Query: 1924 SELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTALQAS 1983 S + A TT S + S GLVEE H S +Q + E+ST + ++ Sbjct: 1889 SSPV-ATATTPS-----PARSTTSGLVEESTAYH----SSPGSTQTMHFPESSTASGRSE 1938 Query: 1984 VARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSRPAS 2043 +R +S S +VE+ T S +G S ++ Sbjct: 1939 ESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR----SEEST 1994 Query: 2044 ASSSTKDITSAV 2055 AS S++D T + Sbjct: 1995 ASHSSQDATGTI 2006 Score = 82.0 bits (201), Expect = 5e-15 Identities = 217/1031 (21%), Positives = 359/1031 (34%), Gaps = 158/1031 (15%) Query: 1050 VSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNS 1109 V + PR L+P S P Q S + P P P+ +T + Sbjct: 3749 VHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSP 3808 Query: 1110 RKMVYQESPQNPSSSPLAEMASL----PEASG---SEAPSVPGGPNNMPSHVVLPQNQLM 1162 P + ++S +E +++ P+ASG S A S G + + P + + Sbjct: 3809 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 3868 Query: 1163 MTGP----KPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPR 1218 T P PG S S T ++P+ P P+S + T S+P + ++ Sbjct: 3869 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS-THSTVS 3927 Query: 1219 PYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPT 1278 P TP ST + S SP ++ FP T Sbjct: 3928 PASTTTPGLSEEST--TVYSSSPGSTETTV---FP----------------------RST 3960 Query: 1279 TLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGS-- 1336 T + P+ P A+ T SG S A SP++++ P + Sbjct: 3961 TTSVRREEPTTFHSRP---ASTHTTLFTEDSTTSGLTEESTAFP-GSPASTQTGLPATLT 4016 Query: 1337 ----SRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPN 1392 ++T P S KL+ A T + L+ R +SP+ +PGS P Sbjct: 4017 TADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSR---LSPSSTETTTLPGS-PT 4072 Query: 1393 NSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMV 1452 L+ +++T + P+ D S PA Sbjct: 4073 TPSLSEKSTTFYTS---------------PRSPDATLS--------------PATTTSSG 4103 Query: 1453 VPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTD 1512 V E+ S QP + + A ++ T+ S P + G T+ Sbjct: 4104 VSEESSTSHSQPGSTH------------TTAFPDSTTTSGL----SQEPTTSHSSQGSTE 4147 Query: 1513 LEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVA 1572 ++P + L + S SS + + LP + + S LV E S + + Sbjct: 4148 ATLSPGSTTASSLGQQST-----TFHSSPGDTETTLLP-DDTITSGLV--EASTPTHSST 4199 Query: 1573 PSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMP 1632 S+ ++ P SS+S + +S+ T S ++ A+P + + S + P Sbjct: 4200 GSLHTTLT-PASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTP 4258 Query: 1633 N---AGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGL 1689 + S + + + ++ P + S V+ G +P+T P + +T + Sbjct: 4259 TTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVG-EPTTSPISSGSTETTA 4317 Query: 1690 MPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLP-SPPC 1748 +P S G ++ F S+P P+ + SPA +G V T P S Sbjct: 4318 LPGSTTTAGLSE--KSTTFYSSPRSPDT-TLSPASTTSSG---VSEESTTSHSRPGSMHT 4371 Query: 1749 TSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLT---NSPGSSG 1805 T+ P + P V Q E +SP S D P S + + + P T +SPGS+ Sbjct: 4372 TAFPSSTTMPGVSQ--ESTASHSSP---GSTDTTLSPGSTTASSLGPESTTFHSSPGSTE 4426 Query: 1806 NRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLM 1865 P +++ L +A V S G T QG TT Sbjct: 4427 TTLLPDNTTASG----------LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWP 4476 Query: 1866 GTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSV-RSIVTTLVPS 1924 ++ TP PP T + S G+ S+ P+ A T++ RS +T V S Sbjct: 4477 NSK-------DTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHS 4529 Query: 1925 ELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTALQASV 1984 + A TT S + S GLVEE H S +Q + E++TT+ + Sbjct: 4530 SPV-ATATTPS-----PARSTTSGLVEESTTYH----SSPGSTQTMHFPESNTTSGRGEE 4579 Query: 1985 ARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSRPASA 2044 + +S S +VE+ T S +G S ++A Sbjct: 4580 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR----SEESTA 4635 Query: 2045 SSSTKDITSAV 2055 S S++D T + Sbjct: 4636 SHSSQDATGTI 4646 Score = 79.0 bits (193), Expect = 5e-14 Identities = 216/1031 (20%), Positives = 355/1031 (34%), Gaps = 158/1031 (15%) Query: 1050 VSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNS 1109 V + PR L+P S P Q S + P P P+ +T + Sbjct: 2666 VHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSP 2725 Query: 1110 RKMVYQESPQNPSSSPLAEMASL----PEASG---SEAPSVPGGPNNMPSHVVLPQNQLM 1162 P + ++S +E +++ P+ASG S A S G + + P + + Sbjct: 2726 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 2785 Query: 1163 MTGP----KPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPR 1218 T P PG S S T ++P+ P P+S + T S+P + ++ Sbjct: 2786 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS-THSTVS 2844 Query: 1219 PYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPT 1278 P TP ST + S SP ++ FP T Sbjct: 2845 PASTTTPGLSEEST--TVYSSSPGSTETTV---FP----------------------RST 2877 Query: 1279 TLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGS-- 1336 T G+ P+ P A+ T SG S A SP++++ P + Sbjct: 2878 TTSVRGEEPTTFHSRP---ASTHTTLFTEDSTTSGLTEESTAFP-GSPASTQTGLPATLT 2933 Query: 1337 ----SRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPN 1392 ++T P S L+ A T + L+ R +SP+ +PGS P Sbjct: 2934 TADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSR---LSPSSTETTTLPGS-PT 2989 Query: 1393 NSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMV 1452 L+ +++T + P+ D S PA Sbjct: 2990 TPSLSEKSTTFYTS---------------PRSPDATLS--------------PATTTSSG 3020 Query: 1453 VPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTD 1512 V E+ S QP + + A ++ T+ S P + G T+ Sbjct: 3021 VSEESSTSHSQPGSTH------------TTAFPDSTTTSGL----SQEPTASHSSQGSTE 3064 Query: 1513 LEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVA 1572 ++P + L + S SS + + LP + + S LV E S + + Sbjct: 3065 ATLSPGSTTASSLGQQST-----TFHSSPGDTETTLLP-DDTITSGLV--EASTPTHSST 3116 Query: 1573 PSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMP 1632 S+ ++ P SS+S + +S+ T S + A P + + S + P Sbjct: 3117 GSLHTTLT-PASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP 3175 Query: 1633 N---AGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGL 1689 + S + + + ++ P + S V+ G +P+T P + +T + Sbjct: 3176 TTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVG-EPTTSPISSGSTETTA 3234 Query: 1690 MPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLP-SPPC 1748 +P S G ++ F S+P P+ + SPA +G V T P S Sbjct: 3235 LPGSTTTAGLSE--KSTTFYSSPRSPDT-TLSPASTTSSG---VSEESTTSHSRPGSTHT 3288 Query: 1749 TSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLT---NSPGSSG 1805 T+ P + P V Q E +SP S D P S + + + P T + PGS+ Sbjct: 3289 TAFPGSTTMPGVSQ--ESTASHSSP---GSTDTTLSPGSTTASSLGPESTTFHSGPGSTE 3343 Query: 1806 NRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLM 1865 P +++ L +A V S G T QG TT Sbjct: 3344 TTLLPDNTTASG----------LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWP 3393 Query: 1866 GTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSV-RSIVTTLVPS 1924 ++ TP PP T + S G+ S+ P+ A T++ RS +T V S Sbjct: 3394 NSK-------DTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHS 3446 Query: 1925 ELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTALQASV 1984 + A TT S + S GLVEE H S +Q + E+ TT+ + Sbjct: 3447 SPV-ATATTPS-----PARSTTSGLVEESTTYH----SSPGSTQTMHFPESDTTSGRGEE 3496 Query: 1985 ARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSRPASA 2044 + +S S +VE+ T S +G S ++A Sbjct: 3497 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR----SEESTA 3552 Query: 2045 SSSTKDITSAV 2055 S S++D T + Sbjct: 3553 SHSSQDATGTI 3563 Score = 73.2 bits (178), Expect = 3e-12 Identities = 227/1098 (20%), Positives = 381/1098 (34%), Gaps = 155/1098 (14%) Query: 1050 VSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNS 1109 V + PR L+P S P Q S + P P P+ +T + Sbjct: 2192 VHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSP 2251 Query: 1110 RKMVYQESPQNPSSSPLAEMASL----PEASG---SEAPSVPGGPNNMPSHVVLPQNQLM 1162 P + ++S +E +++ P+ASG S A S G + + P + + Sbjct: 2252 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 2311 Query: 1163 MTGP----KPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPR 1218 T P PG S S T ++P+ P P+S + T S+P + ++ Sbjct: 2312 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS-THSTVS 2370 Query: 1219 PYYPQTPNNRPPSTE-------PSEISLSPERLNASIAGLFPPQINI-PLPPRPNL-NRG 1269 P TP ST +E ++ P S+ G P + P L Sbjct: 2371 PASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTED 2430 Query: 1270 FDQQGLNPTTLKAIGQAPSNLTMNPSNFAT----------PQTHKLDSVVVNSGKQSNSG 1319 GL + G S T P+ T P + ++ + + SG Sbjct: 2431 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2490 Query: 1320 ATKRASPSNSRRSS------PGSSRKTTPSPGRQNS------KAPKLTL--ASQTNAALL 1365 ++PS SS PGS TTPS +++ ++P TL A+ T++ + Sbjct: 2491 LVGESTPSRLSPSSTETTTLPGS--PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVS 2548 Query: 1366 QNVELPRNVLVSPTPLANP---PVPG----SFPNNSGLNPQNSTVSVAA--VGGVVEDNK 1416 + + S A P PG S ++S ++T+ A+ G +++ Sbjct: 2549 EESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST 2608 Query: 1417 ESLNVPQDSDCQNSQSRKE-----QVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLP 1471 S + P +D S Q + + P + P+ + + Sbjct: 2609 TSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHS 2668 Query: 1472 SVEENKNLVSPAMREAP----------TSLSQLLDNSGAPNVTIKP----------PGLT 1511 S + +SPA +P T + P+ P PG T Sbjct: 2669 STGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 2728 Query: 1512 DLEVTP--PVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSS 1569 P SG +K+++ + D S + S E +S + P +E+++ Sbjct: 2729 PTTHFPASSTTSGHS-EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 2787 Query: 1570 NVAPSIPPVMSRPVSSSSISTPLPPNQI--TVFVTSNPITTSANTSAALPTHLQSALMST 1627 + P +S S++ S+P P +TS + + TS + P S + Sbjct: 2788 LPGSTTTPGLSE-ASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2846 Query: 1628 VVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNS 1687 T P +SE + S++ T VF S++ ++G +P+T + P +T++ Sbjct: 2847 STTTPG------LSEESTTVYSSSPGSTETTVFPRSTT--TSVRGEEPTTFHSRPASTHT 2898 Query: 1688 GLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPP 1747 L ++ S A SPA + QTG P L++ + + P Sbjct: 2899 TL------------FTEDSTTSGLTEESTAFPGSPA-STQTGLPATLTTADLGEESTTFP 2945 Query: 1748 CTSSPVVPSHPPVQQ-----VKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPG 1802 +S + P + V E P SP +S + TLP S +T +S T Sbjct: 2946 SSSGSTGTTLSPARSTTSGLVGESTPSRLSP---SSTETTTLPGSPTTPSLSEKSTTFYT 3002 Query: 1803 SSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGL--DTT 1860 S RSP ++ L+ A +G E+ + G T TT Sbjct: 3003 SP---RSPDAT--------------LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTT 3045 Query: 1861 APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT 1920 GL S T +P T+S +G + + S PG T + Sbjct: 3046 TSGLSQEPTASHSSQGSTEATLSPG--STTASSLGQQSTTFHSS-PG---DTETTLLPDD 3099 Query: 1921 LVPSELISAVPTTKSNHGGI-----ASESLAGGLVEEKV-----GSHPELLPSIAPSQNL 1970 + S L+ A T S+ G + + S + GL EE S + PS P Sbjct: 3100 TITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS-PPGTTA 3158 Query: 1971 VSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESV 2030 E STT + P +A+ + SE V S PG + PT ++ SV Sbjct: 3159 APVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS--PGATGTAL-FPTRSATSV 3215 Query: 2031 ENGHRKRSSRPASASSST 2048 G S + ++ +T Sbjct: 3216 LVGEPTTSPISSGSTETT 3233 Score = 66.2 bits (160), Expect = 3e-10 Identities = 216/1029 (20%), Positives = 358/1029 (34%), Gaps = 165/1029 (16%) Query: 1089 PPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSS--SPLAEMASLPEASGSEAPSVPGG 1146 P S + +P TP + + + SP++P + SP +S S + S PG Sbjct: 2502 PSSTETTTLPGSPTTP-SLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGS 2560 Query: 1147 PNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQT 1206 + P + PG S S T ++P LP+S P+ + T Sbjct: 2561 THT----TAFPDSTTT-----PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 2611 Query: 1207 SRP-KTPNRASP-----------RPYYPQTPNNR-----PPSTEPSEISLSPERLNASIA 1249 S P T SP + +P + P ST S I + R+++S Sbjct: 2612 SSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 2671 Query: 1250 GLFPPQINIPLPPRPNLNRGFDQQG----LNPTTLKAIGQAPS--------NLTMNPSNF 1297 P+ L P + + G + +P + PS + T + S Sbjct: 2672 S---PRTT--LSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG 2726 Query: 1298 ATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLA 1357 +TP TH + SG S T S ++ ++P S+ TT GR S +++ Sbjct: 2727 STPTTH-FPASSTTSGHSEKS--TIFHSSPDASGTTPSSAHSTT--SGRGESTTSRISPG 2781 Query: 1358 SQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKE 1417 S L + P S T ++P P + L+P + T Sbjct: 2782 STEITTLPGSTTTPGLSEASTTFYSSPRSP-----TTTLSPASMT--------------- 2821 Query: 1418 SLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENK 1477 SL V ++S SQ + PA + E+ + S P + + Sbjct: 2822 SLGVGEESTTSRSQPGSTHSTVS----PASTTTPGLSEESTTV--YSSSPGSTETTVFPR 2875 Query: 1478 NLVSPAMREAPTSLSQLLDNSGAPNVT--IKPPGLTDLEVTPPVVSGEDLKKASVIPTLQ 1535 + + E PT+ ++ T GLT+ P G + +P Sbjct: 2876 STTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP---GSPASTQTGLPA-- 2930 Query: 1536 DLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPP- 1594 L+++ S P S+ + + P S S V S P +S P S+ + + P P Sbjct: 2931 TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLS-PSSTETTTLPGSPT 2989 Query: 1595 -----NQITVFVTS--------NPITTSAN--TSAALPTHLQSALMSTVVTMPNAGSKVM 1639 + T F TS +P TT+++ + + +H Q T P++ + Sbjct: 2990 TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT-TAFPDSTTTSG 3048 Query: 1640 VSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGP 1699 +S+ +A+ S+ Q T ++ S G Q +T ++P T + L+P G Sbjct: 3049 LSQEPTASHSS---QGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGL 3105 Query: 1700 LHIPQNIKFSSAPVPPNAL-SSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHP 1758 + S+ + +SS + +Q S ++ PSPP T++ V Sbjct: 3106 VEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPV---- 3161 Query: 1759 PVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKG 1818 V P ++P + SA TL S+ +T V +SPG++G P S+ Sbjct: 3162 EVSTTYHSRP-SSTPTTHFSASSTTLGRSEESTTVH----SSPGATGTALFPTRSATS-- 3214 Query: 1819 KVDKIGQILLTKACKKVTGSLEKGE-EQYGADGETEGQGLDTTAPGLMGTEQLSTELDSK 1877 + T + G E G T GL + + + S Sbjct: 3215 ----------VLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 3264 Query: 1878 TPTPPAPTLLKMTSSPVGPG----------TASAGPSLPGGALPTSVRSIVTTLVPSELI 1927 T + + T+S PG T G S A +S S TTL P Sbjct: 3265 ASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTT 3324 Query: 1928 --SAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTALQASVA 1985 S P + + H G S + LLP + L+ ++T + +S Sbjct: 3325 ASSLGPESTTFHSGPGS-------------TETTLLPDNTTASGLLE---ASTPVHSSTG 3368 Query: 1986 RPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVE---NGHRKRSSRPA 2042 P ++ A G ++ E P +++ PT S VE H SS P Sbjct: 3369 SPHTTLSPA---GSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPT 3425 Query: 2043 ---SASSST 2048 SASS+T Sbjct: 3426 THFSASSTT 3434 Score = 65.9 bits (159), Expect = 4e-10 Identities = 196/889 (22%), Positives = 308/889 (34%), Gaps = 121/889 (13%) Query: 1115 QESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVV---LPQNQLMMTGPKPGPS 1171 +ES + SS LP S PSV G ++ PS + + L + KPG S Sbjct: 578 EESKASHSSPDAMATTVLPAGS---TPSVLVG-DSTPSPISSGSMETTALPGSTTKPGLS 633 Query: 1172 PLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRP-KTPNRASP----RPYYPQTPN 1226 S T ++P+ P LP+S + + T SRP T A P P Q Sbjct: 634 EKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQEST 693 Query: 1227 NRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQA 1286 S P++ +LSP AS G P + G TTL Sbjct: 694 ASHSSPGPTDTTLSPGSTTASSLG-------------PEYTTFHSRPGSTETTL-----L 735 Query: 1287 PSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGR 1346 P N T + A+ H S S +G+T R S + S P SS+ T P+P Sbjct: 736 PDNTTASGLLEASMPVH--SSTRSPHTTLSPAGSTTRQGESTTFHSWP-SSKDTRPAPPT 792 Query: 1347 QNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLN-PQNSTVSV 1405 S + + S + + + + S + S + ++ P++ T S Sbjct: 793 TTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG 852 Query: 1406 AAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPS 1465 G S S ++ S + + P P+ + Sbjct: 853 R---GEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 909 Query: 1466 DPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDL 1525 S + +V PA ++ S LL S T P+ SG Sbjct: 910 STASHSSQDATGTIVLPAR----STTSVLLGES----------------TTSPISSGS-- 947 Query: 1526 KKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSS 1585 + + +P E S + HS+ + S SS V+ SRP Sbjct: 948 METTALPGSTTTPGLSERSTTF---HSSPRSPATTLSPASTTSSGVSEESTTSRSRP--- 1001 Query: 1586 SSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQS 1645 S T P+ T S TTS ++ + T L A ST + P+ S S S Sbjct: 1002 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA--STTTSGPSQESTTSHSSSGS 1059 Query: 1646 AAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQN 1705 T ++ S + G + +T + P +T++ L P S G + Sbjct: 1060 -----------TDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTR 1108 Query: 1706 IKFSSAPVPPNALS--SSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQV 1763 + SS P LS SS +P +Q + A+ PSPP T++ PV++ Sbjct: 1109 V-HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT------APVEES 1161 Query: 1764 KELNPDEAS-PQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPV-SSSKGKGKVD 1821 + S P + A T S+ +T + +SP +SG S S++ G+G Sbjct: 1162 TTYHRSPGSTPTTHFPASSTTSGHSEKST----IFHSSPDASGTTPSSAHSTTSGRG--- 1214 Query: 1822 KIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTP 1881 + T + G + T G TT PGL + ST S +P Sbjct: 1215 -----------ESTTSRISPGSTEI-----TTLPG-STTTPGL---SEASTTFYS-SPRS 1253 Query: 1882 PAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIA 1941 P TL + + +G G S G+ ++V S +T P + S+ G Sbjct: 1254 PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV-SPASTTTPGLSEESTTVYSSSRGSTE 1312 Query: 1942 SESLAGGLVEEKVGSHPELLPSIAPSQN--LVSKETSTTAL-QASVARP 1987 + G P S S + L +++++T+ L + S A P Sbjct: 1313 TTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP 1361 Score = 53.9 bits (128), Expect = 2e-06 Identities = 201/966 (20%), Positives = 335/966 (34%), Gaps = 131/966 (13%) Query: 1102 NTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNN--MPSHVVLPQN 1159 +TP S++ + +P + +S+ L E ++ ++ S + + P P+ +P V + Sbjct: 4192 STPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYH 4251 Query: 1160 QLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHH-FPNVAAPTQTSRPKTPNRASPR 1218 + P S S T G + + V+S P + G FP +A + T SP Sbjct: 4252 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPT---TSPI 4308 Query: 1219 PYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLN-- 1276 P ST + +S +S P + L P + G ++ Sbjct: 4309 SSGSTETTALPGSTTTAGLSEKSTTFYSS-----PRSPDTTLSPASTTSSGVSEESTTSH 4363 Query: 1277 --PTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSP 1334 P ++ PS+ TM + + +H + ++ A+ S + SSP Sbjct: 4364 SRPGSMHTTA-FPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSP 4422 Query: 1335 GSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNS 1394 GS+ +TT P N+ A L AS + + + S T S+PN+ Sbjct: 4423 GST-ETTLLP--DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSK 4479 Query: 1395 GLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQS---RKEQVNIELKAV------- 1444 P T + A V + + P +S + +E + V Sbjct: 4480 DTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 4539 Query: 1445 PAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVT 1504 PA+ + E+ + P + E N S E+ TS +S + Sbjct: 4540 PARSTTSGLVEESTTYHSSPGSTQTMHFPESNTT--SGRGEESTTS------HSSTTHTI 4591 Query: 1505 IKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNE-LCSSLVHPE 1563 P T V P S ++ D S++ S HS++ ++V P Sbjct: 4592 SSAPSTTSALVEEPT-SYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 4650 Query: 1564 LSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALP------ 1617 S S + S + P+SS S+ T P T S TT ++ ++ P Sbjct: 4651 RSTTSVLLGEST----TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSA 4706 Query: 1618 -----------THLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSI 1666 T + S+ ++T T A S +S A ++ T F SS+ Sbjct: 4707 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTA 4766 Query: 1667 IQVMKGSQPS------TIPAAPLTTNSGLMPP-----SVAVVGPLHIPQNIKFSSAPVPP 1715 + S+ S TI + P TT++ + P S + H P++ S Sbjct: 4767 SGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEES 4826 Query: 1716 NALSSSPAPNIQTGRP--------------LVLSSRATPVQLPSPPCTSSPVVPSHPPVQ 1761 A SSP N T P +S + L S T P + + + Sbjct: 4827 TASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATT--PGLSAKSTIL 4884 Query: 1762 QVKELNPDEA-SPQVNTSAD----------------QNTLPSSQSTTMVSPLLT---NSP 1801 +PD+ SP TS+ P+S +T+ +S T + P Sbjct: 4885 YSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKP 4944 Query: 1802 GSSGNRRSPVSSSKGKGKVD------KIGQILLT--KACKKVTGSLEKGEEQYGADGETE 1853 GS+ SP S + + + G L T A V G E+ Y + G TE Sbjct: 4945 GSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTE 5004 Query: 1854 GQGLDTTAPGLMGTEQLSTELDSKTPTPPAP----TLL--KMTSSPVG-PGTASAGPSLP 1906 TTA + +S TP P +P T+L +T++ +G TA S Sbjct: 5005 -----TTA--FSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDA 5057 Query: 1907 GGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSH--PELLPSI 1964 G P RS + LV + + + + S GL EE H P +I Sbjct: 5058 TGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTI 5117 Query: 1965 APSQNL 1970 +++L Sbjct: 5118 VSTESL 5123 Score = 50.8 bits (120), Expect = 1e-05 Identities = 200/1008 (19%), Positives = 342/1008 (33%), Gaps = 192/1008 (19%) Query: 1106 GSNSRKMVYQESPQNPSSSPLAEMASLPE---ASGSEAPSVPGGPNNMPSHVVLPQNQLM 1162 GS + + Q+S SS E LP+ SG S P + H L Sbjct: 1513 GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASST 1572 Query: 1163 MTGPKPGPSPLSA---TQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRP 1219 G + + + + TP P + P + T SRP + +P Sbjct: 1573 SAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVE--------VSTTYHSRPSS----TPTT 1620 Query: 1220 YYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQ----INIPLPPRPNLNRGFDQQGL 1275 ++ + S E + + SP A+ LFP + + + P ++ G + Sbjct: 1621 HFSASSTTLGRSEESTTVHSSP---GATGTALFPTRSATSVLVGEPTTSPISSGSTETTA 1677 Query: 1276 NPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSS-- 1333 P + G + + T +++P++ ++ ++SG ++ ++ S+SR S Sbjct: 1678 LPGSTTTAGLSEKSTTF----YSSPRS---PDTTLSPASTTSSGVSEESTTSHSRPGSTH 1730 Query: 1334 ----------PGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLAN 1383 PG S+++T S S L+ S T ++L P Sbjct: 1731 TTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSL------------GPESTTF 1778 Query: 1384 PPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNK---ESLNVPQDSDCQNSQSRKEQVNIE 1440 PGS + L P N+T S G++E + S P + + ++ + Sbjct: 1779 HSSPGS--TETTLLPDNTTAS-----GLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 1831 Query: 1441 LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTS----LSQLLD 1496 ++ P S KD P+ P + E + PT+ S L Sbjct: 1832 FQSWP------------SSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG 1879 Query: 1497 NSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELC 1556 S P T +P + L + S SS + +++ P S+ Sbjct: 1880 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTA-----YHSSPGSTQTMHFPESSTAS 1934 Query: 1557 SSLVHPELSEVSSNVAPSIPP-----VMSRPVS-----SSSISTPLP------------- 1593 S S+ S PP ++ P S S+ +T P Sbjct: 1935 GRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 1994 Query: 1594 --------------PNQITVFV-----TSNPITTSANTSAALP------------THLQS 1622 P + T V T++PI++ + + ALP T S Sbjct: 1995 ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHS 2054 Query: 1623 ALMSTVVTMPNAGSKVMVSEGQSAAQSNARP-QFITPVFINSSSIIQVMKGSQPSTIPAA 1681 + S T+ A S + + S++RP T F +S++ + + S +T ++ Sbjct: 2055 SPRSPATTLSPA-STTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHS--TTSHSS 2111 Query: 1682 PLTTNSGLMPPSVAVVGPLH-------IPQNIKFSSAPVPPNALS---------SSPA-- 1723 P +T++ L+P S GP P + + +P ALS SSP Sbjct: 2112 PGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGST 2171 Query: 1724 -----PNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTS 1778 P+ T +V +S SP T SP + P +Q E++ Sbjct: 2172 HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQ-------GESTAFQTHP 2224 Query: 1779 ADQNTLPSSQSTTMV----SPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKK 1834 A +T PS ST S SPGS+ P SS+ G +K + Sbjct: 2225 ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT-SGHSEKSTIFHSSPDASG 2283 Query: 1835 VTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPV 1894 T S A T G+G TT+ G+ +++T S T + SSP Sbjct: 2284 TTPS--------SAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 2335 Query: 1895 GPGTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKV 1954 P T + S+ +L S + P S V + G++ ES + Sbjct: 2336 SPTTTLSPASMT--SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTT--VYSSSP 2391 Query: 1955 GSHPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSE 2002 GS + P+ ++ +E +T + + L + SG + E Sbjct: 2392 GSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 2439 Score = 49.3 bits (116), Expect = 4e-05 Identities = 216/1065 (20%), Positives = 367/1065 (34%), Gaps = 164/1065 (15%) Query: 1089 PPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSS--SPLAEMASLPEASGSEAPSVPGG 1146 P S + +P TP + + + SP++P + SP +S S + S PG Sbjct: 2976 PSSTETTTLPGSPTTP-SLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGS 3034 Query: 1147 PNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQ-PPVNSLPSSHGHHFPNV-AAPT 1204 +H + +G P+ ++QG+T P ++ SS G ++P Sbjct: 3035 -----THTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPG 3089 Query: 1205 QTSRPKTPNRASPRPYYP-QTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPR 1263 T P+ TP + ST +L+P +++ AGL P Sbjct: 3090 DTETTLLPDDTITSGLVEASTPTHS--STGSLHTTLTPA--SSTSAGLQEESTTFQSWPS 3145 Query: 1264 PNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTH-KLDSVVVNSGKQSNS---- 1318 + D P T A + + PS+ TP TH S + ++S + Sbjct: 3146 SS-----DTTPSPPGTTAAPVEVSTTYHSRPSS--TPTTHFSASSTTLGRSEESTTVHSS 3198 Query: 1319 -GATKRAS-PSNSRRSSPGSSRKTTP--SPGRQNSKAPKLTLASQTNAALLQNVELPRNV 1374 GAT A P+ S S T+P S + + P T + + PR+ Sbjct: 3199 PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 3258 Query: 1375 LVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRK 1434 + +P + S + + + ST + A G V Q+S +S Sbjct: 3259 DTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG-----VSQESTASHSSPGS 3313 Query: 1435 EQVNIELKAVPAQEVKMVVPEDQSKKDGQPS-DPNKLPSVEENKNLVSPAMREAPTSLSQ 1493 + + A + PE + G S + LP N + + EA T + Sbjct: 3314 TDTTLSPGSTTASSLG---PESTTFHSGPGSTETTLLPD-----NTTASGLLEASTPVHS 3365 Query: 1494 LLDNSGAPNVTIKPPGLT----------------DLEVTPPVVSGEDLKKA-------SV 1530 ++G+P+ T+ P G T D PP + ++ + S Sbjct: 3366 ---STGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSS 3422 Query: 1531 IPTLQDLSSSKE--PSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSI 1588 PT +SS S HS+ + ++ +S + S P S+ ++ Sbjct: 3423 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTM 3482 Query: 1589 STP-------------LPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVT-MPNA 1634 P + T ++S P TTSA PT S+ ST T P++ Sbjct: 3483 HFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--PTSYHSSPGSTATTHFPDS 3540 Query: 1635 GSKVMVSEGQSAAQSNARP--------QFITPVFINSSSIIQVMKGSQPST-IPAAPLTT 1685 + SE +A+ S+ + T V + S+ + GS +T +P + TT Sbjct: 3541 STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS--TT 3598 Query: 1686 NSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPS 1745 GL S F S+P P A + SPA +G V T P Sbjct: 3599 TPGLSEKSTT------------FHSSPRSP-ATTLSPASTTSSG---VSEESTTSHSRPG 3642 Query: 1746 -------PPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLT 1798 P T++P + H +SP S D LP+S +T+ S T Sbjct: 3643 STHTTAFPDSTTTPGLSRHSTTSH--------SSPG---STDTTLLPASTTTSGSSQEST 3691 Query: 1799 NSPGSSGNRRSPVSSSKGKGKVDKIGQ-------------ILLTKACKKVTGSLEKGEEQ 1845 S SSG+ + + S G GQ L +G +E Sbjct: 3692 TSHSSSGS--TDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV 3749 Query: 1846 YGADG--ETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTA--SA 1901 + + G T +T+PGL G + T T P+P ++PV T + Sbjct: 3750 HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPP--STATAPVEESTTYHRS 3807 Query: 1902 GPSLPGGALP----TSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSH 1957 S P P TS S +T+ S ++ T S H ++ S G ++ Sbjct: 3808 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAH---STTSGRGESTTSRISPG 3864 Query: 1958 PELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRN 2017 + ++ S ++T +S P ++ A ++ + +S+ PG + Sbjct: 3865 STEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQ-PGSTH 3923 Query: 2018 SRTEEPTVASESV-ENGHRKRSSRPASASSSTKDITSAVQSKRRK 2061 S + + + E SS P S ++ ++ +R + Sbjct: 3924 STVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREE 3968 Score = 48.9 bits (115), Expect = 5e-05 Identities = 190/941 (20%), Positives = 318/941 (33%), Gaps = 183/941 (19%) Query: 1094 KQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASG--SEAPSVPGGPNNMP 1151 K MP P P +++ + S +PSS+P ++ G E+ +V P Sbjct: 1839 KDTMPAP---PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP---- 1891 Query: 1152 SHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLP-SSHGHHFPNVAAPT------ 1204 + T P P+ S T G + +S P S+ HFP + + Sbjct: 1892 ----------VATATTPSPAR-STTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEES 1940 Query: 1205 QTSRPKTPNRASPRPYY-------PQTPNNRPPSTEPSEI---SLSPERLNASIAGLFPP 1254 +TS T + S P P + ++ P ST + S + R S A Sbjct: 1941 RTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 2000 Query: 1255 QIN--IPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATP----------QT 1302 I LP R + L +T I T P + TP + Sbjct: 2001 DATGTIVLPARSTTS-----VLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSS 2055 Query: 1303 HKLDSVVVNSGKQSNSGATKRASPSNSRRSS------------PGSSRKTTPSPGRQNSK 1350 + + ++ ++SG ++ ++ S+SR S PG SR +T S S Sbjct: 2056 PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 2115 Query: 1351 APKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGG 1410 L AS T + Q + SP PGS S Q ST ++ G Sbjct: 2116 DTTLLPASTTTSGPSQESTTSHS---SPGSTDTALSPGSTTALSF--GQESTTFHSSPGS 2170 Query: 1411 ----VVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSD 1466 + D+ S + + S +S + + + PA + + + P+ Sbjct: 2171 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS----PASSTSPGLQGESTAFQTHPAS 2226 Query: 1467 PNKLPS--------VEEN--------------------------KNLVSPAMREA----P 1488 + PS VEE+ K+ + + +A P Sbjct: 2227 THTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP 2286 Query: 1489 TSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLN 1548 +S G + PG T++ P + L +AS SS + P+ +L+ Sbjct: 2287 SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTT----FYSSPRSPTTTLS 2342 Query: 1549 LPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITT 1608 +S+ + E S + S P VS +S +TP + T +S+P +T Sbjct: 2343 P-------ASMTSLGVGE-ESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGST 2394 Query: 1609 SANTSAALPT-----------HLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFIT 1657 PT H + A T + ++ + + E + S A Q Sbjct: 2395 ETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGL 2454 Query: 1658 PVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNA 1717 P + ++ + G + +T P++ +T + L P G + + S + Sbjct: 2455 PATLTTADL-----GEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTT 2509 Query: 1718 LSSSP-APNIQTGRPLVLSSRATPVQLPSPPCTSSPVVP-------SHPPVQQVKELNPD 1769 L SP P++ +S +P SP T+S V S P Sbjct: 2510 LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS 2569 Query: 1770 EASPQVNT-SADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILL 1828 +P ++ S ++ P S TT LL S +SG + +S G D Sbjct: 2570 TTTPGLSRHSTTSHSSPGSTDTT----LLPASTTTSGPSQESTTSHSSPGSTD------- 2618 Query: 1829 TKACKKVTGSLEKGEEQ---YGADGETEGQGL--DTTAPGLMGTEQLSTELDSKTPTPPA 1883 T T +L G+E + + G T TT+ G++ + ST + S T +P Sbjct: 2619 TALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIV---EASTRVHSSTGSP-- 2673 Query: 1884 PTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLVPS 1924 + T SP +S P L G + T PS Sbjct: 2674 ----RTTLSP----ASSTSPGLQGESTTFQTHPASTHTTPS 2706 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 84.3 bits (207), Expect = 1e-15 Identities = 152/583 (26%), Positives = 205/583 (35%), Gaps = 152/583 (26%) Query: 200 NPELQPRTPRPA---SQSDAMDPLL----------SGLHIQQQS---HPSGSLAPPHHPM 243 +P + P TP P SQ MDP++ S H Q Q +P GS PP Sbjct: 440 HPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQR 499 Query: 244 QPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQP---- 299 P+ + + A Q QQQ ++ PPQ QQ Sbjct: 500 YPIGIQGRTPGA----------MAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQ 549 Query: 300 QGIRPQFTAPTQVP-VPPGWNQLPSGA---LQPPPAQGSLGTMTANQGWKKAPL-PG-PM 353 QG +P ++ Q P +PP LPS + QP G T +Q PL PG P Sbjct: 550 QGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQ----PPLAPGKPN 605 Query: 354 QQQL----QARPSLATVQTPSHPPPPYPFGSQ-------QASQAHTNFPQMSNPGQ---- 398 + L Q RPS ++ S P G++ AS + ++ SNP Q Sbjct: 606 HEDLNLIQQERPS--SLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFS 663 Query: 399 -FTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRP 457 +P + S+ GGPS P+P+ GSP V Q + GP Sbjct: 664 PHASPHLSSIPGGPS--PSPV-------------------GSP-----VGSNQSRSGPIS 697 Query: 458 PQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPP 517 P + P G Q P PG +Q S HP L P Sbjct: 698 PASIP---GSQMPPQPPG----------------------SQSESSSHPALSQSPMPQER 732 Query: 518 GFSAG-QANPNFMQ-GQVPSTTATTPGNSGAPQLQAN-QNVQHAGGQGAGPPQNQMQVSH 574 GF AG Q NP Q G + + +P S Q+ A + Q + G ++ Sbjct: 733 GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG----------TY 782 Query: 575 GPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQ 634 GP Q S G GN + A SGVP + S P MG+ S Sbjct: 783 GP----QMSQYGPQGNYSRPPA-YSGVPSASYSG---------PGPGMGI------SANN 822 Query: 635 MVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAP 694 + QG P + L R MP M P N+ MTP +SQQG M P Sbjct: 823 QMHGQGPSQPCGAVPLGR---MPSAGMQNRPFPGNM----SSMTPSSPGMSQQGGPGMGP 875 Query: 695 HNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVM 737 + + Q + + Q N Q + F NQS +M Sbjct: 876 PMPTVNRKAQ---EAAAAVMQAAANSAQSRQGSFPGMNQSGLM 915 Score = 83.6 bits (205), Expect = 2e-15 Identities = 245/1062 (23%), Positives = 335/1062 (31%), Gaps = 200/1062 (18%) Query: 260 LQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWN 319 LQQQ Q QQQQQQQQQQQQQQQQQQ Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQ---------------------------------- 73 Query: 320 QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFG 379 P SLG AP PGP +Q Q + + PP P Sbjct: 74 -------HPISNNNSLGGAGGG-----APQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL 121 Query: 380 SQQASQAHTNFPQMSNP--GQFTAPQMKSL--QGGPSRVP----TPLQQPHLTNKSPASS 431 S+ + P+M P G++ P + +L Q P VP P P N +++ Sbjct: 122 SKPGDEDDAP-PKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180 Query: 432 PSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG-RNPMVQQGNVPPNFM 490 P+S G A P + Q G + P + +PG +P+ PN Sbjct: 181 PASGGPGGRA-GPCFD---QHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236 Query: 491 VMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQ 550 N P PG GG G G G +GA Sbjct: 237 C------NHYPGYSRPGAGG------GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAA 284 Query: 551 ANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQ 610 A AGG G G S G + P G G G +LS Sbjct: 285 AAAAAAAAGGGGGGGYGGS---SAGYGVLSSPRQQG-----GGMMMGPGGGGAASLSKAA 336 Query: 611 GQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNL 670 G + G +Q PS Q +P +PM+ S P+ PP Sbjct: 337 AGSAAGGFQRFAGQNQH--PSGATPTLNQLLTSP-SPMMRSYGGSYPEYSSPSAPP---- 389 Query: 671 GPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNT 730 PP Q SQ A Q + L ++ + + QQ + Sbjct: 390 -------PPPSQPQSQAAAAGAAAGGQQAA--AGMGLGKDMGAQYAAASPAWAAAQQRSH 440 Query: 731 QNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRP 790 S PGP QG+ + Q+ ++ P Q G P Sbjct: 441 PAMSPGTPGPTM------GRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP 494 Query: 791 PGPSPH-MAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGH 849 PGP + + Q P A Q D + ++T + P QG SG+ Sbjct: 495 PGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQG-------VSGY 547 Query: 850 GMSFNAP-FSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNN---- 904 P +S P Q P P + Q D+S +G + Sbjct: 548 CQQGQQPYYSQQP--------QPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPL 599 Query: 905 ---KQNNTNANKPKKKKPPRKKKNSQQDLN-TPDTRPAGLEE--ADQPPLPGEQGINLDN 958 K N+ + N ++++P +S DL+ + D P G E + G D Sbjct: 600 APGKPNHEDLNLIQQERP-----SSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQ 654 Query: 959 SGPKLPEFS-------NRPPGYPS-----QPVEQRPLQQMP--PQLMQHVAPPPQPPQQQ 1004 S P FS + PG PS PV + P P + PPQPP Q Sbjct: 655 SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQ 714 Query: 1005 PQPQL-PQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP-PRGPLN 1062 + P Q P P + Q+ QM Q P S + HP P G ++ Sbjct: 715 SESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGP-------SMSPHPSPGGQMH 767 Query: 1063 PD-SQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNP 1121 S SG+ +S GP G+ SR Y P Sbjct: 768 AGISSFQQSNSSGTYGPQMSQYGPQ-------------------GNYSRPPAYSGVPSAS 808 Query: 1122 SSSPLAEMA-SLPEASGSEAPSVPGGP---NNMPS----HVVLPQNQLMMTGPKPGPSPL 1173 S P M S + PS P G MPS + P N MT PG S Sbjct: 809 YSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQ- 867 Query: 1174 SATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRP-------KTPNRASPRPY-YPQTP 1225 G P P VN AA + SR ++ AS PY P Sbjct: 868 QGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNN 927 Query: 1226 NNRPPSTEPSEISLSPERLNASIAG------LFPPQINIPLP 1261 ++ +T+ S++P +N+S A + P + +PLP Sbjct: 928 SSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLP 969 Score = 75.9 bits (185), Expect = 4e-13 Identities = 165/730 (22%), Positives = 266/730 (36%), Gaps = 114/730 (15%) Query: 933 PDTRPAGLEEADQPPLPGEQGINLDNSGPKL--PEFSNRPPGYPSQPVEQRPLQQMPPQL 990 P P G++ + G Q +SG F PP Y Q V Q P Sbjct: 497 PQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYY 556 Query: 991 MQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPV 1050 Q PP PPQ Q P QSQQ+ Q QQ M Q+ R Sbjct: 557 SQQPQPPHLPPQAQYLPS-------------QSQQRYQPQQD------MSQEGYGTR--- 594 Query: 1051 SQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSR 1110 PP P P+ + + + Q + L G P+ + + V+ ++S Sbjct: 595 ---SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS- 650 Query: 1111 KMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGP 1170 Q NP+ SP + AS P S S+PGGP+ P + NQ + GP Sbjct: 651 ----QGDQSNPAQSPFSPHAS-PHLS-----SIPGGPSPSPVGSPVGSNQ-----SRSGP 695 Query: 1171 -SPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229 SP S P QPP + SS + A +Q+ P+ + PQ P Sbjct: 696 ISPASIPGSQMPPQPPGSQSESS------SHPALSQSPMPQERGFMAGTQRNPQMAQYGP 749 Query: 1230 PSTEPSEISLSPE-----RLNASI--------AGLFPPQINIPLPPRPNLNRGFDQQGLN 1276 T P S+SP +++A I +G + PQ++ P+ N +R G+ Sbjct: 750 QQTGP---SMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMS-QYGPQGNYSRPPAYSGVP 805 Query: 1277 PTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRR---SS 1333 + G + ++ +N Q V G+ ++G R P N SS Sbjct: 806 SASYSGPG---PGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSS 862 Query: 1334 PGSSRKTTPSPG-------RQNSKAPKLTLASQTNAALLQNVELP----RNVLVSPTPLA 1382 PG S++ P G R+ +A + + N+A + P ++ S +P + Sbjct: 863 PGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYS 922 Query: 1383 NPPVPGSFPNNSG--LNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE 1440 P NNS +N Q S+A +V + S+ + +D + K + + Sbjct: 923 QP------MNNSSSLMNTQAPPYSMAP--AMVNSSAASVGL---ADMMSPGESK--LPLP 969 Query: 1441 LKAVPAQEVKMVVPEDQSKKDGQPSDP-NKLPSVEENKNLVSPAMREAPTSLSQLLDNSG 1499 LKA +E PE +SKK + K+ V E N P + ++ G Sbjct: 970 LKA-DGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGN--EPERKLWVDRYLTFMEERG 1026 Query: 1500 APNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSL 1559 +P ++ G L++ V +K+ + + +E + +LN+ S+ SSL Sbjct: 1027 SPVSSLPAVGKKPLDLFRLYVC---VKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSL 1083 Query: 1560 VHPELS-----EVSSNVAPSIPPVM---SRPVSSSSISTPLPPNQITVFVTSNPITTSAN 1611 + E PP + + P P N ++ P +T +N Sbjct: 1084 KKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSN 1143 Query: 1612 TSAALPTHLQ 1621 + A +P L+ Sbjct: 1144 SMAEVPGDLK 1153 Score = 74.7 bits (182), Expect = 9e-13 Identities = 234/1038 (22%), Positives = 350/1038 (33%), Gaps = 170/1038 (16%) Query: 317 GWNQLPSGAL--------QPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATV-- 366 G NQ PSGA P P S G AP P P Q Q QA + A Sbjct: 349 GQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGG 408 Query: 367 -QTPSHPPPPYPFGSQ--QASQAHTNFPQMSNPGQ---FTAPQMKSLQGGPSRVPTPLQQ 420 Q + G+Q AS A Q S+P P M QG P P +++ Sbjct: 409 QQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMD-PMVMKR 467 Query: 421 PHL--TNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNP 478 P L +P S P QQ SP + GP PQ P+ + P + G Sbjct: 468 PQLYGMGSNPHSQP---QQSSPYPGGS-------YGPPGPQRYPIGIQGRTPGAMAGMQY 517 Query: 479 MVQQGNVPPNFM-VMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTT 537 QQ + + PP G Q G+ G ++ + + Q P +P Sbjct: 518 PQQQDSGDATWKETFWLMPPQYGQQ----GVSGYCQQGQQPYYSQQPQP----PHLPPQA 569 Query: 538 ATTPGNSGAPQLQANQNVQHAG-GQGAGPPQNQMQVSHGPPNMMQ----PSLMGIHGNMN 592 P S + Q Q++ G G + PP + +H N++Q SL + G+++ Sbjct: 570 QYLPSQS-QQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSID 628 Query: 593 NQQAGT-----SGVPQVNLSNMQG---QPQQGPPSQLMGMHQQIVPS-------QGQMVQ 637 + GT S V ++ QG P Q P S H +P + Sbjct: 629 DLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGS 688 Query: 638 QQGTLNPQNPMILSRAQLMPQ----GQMMVNPPSQNLGPSPQRM-----TPPKQMLSQQG 688 Q P +P + +Q+ PQ + P+ + P PQ T ++Q G Sbjct: 689 NQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYG 748 Query: 689 PQM----MAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPG----P 740 PQ M+PH P GQ+ + + + Q+ Q + P P Sbjct: 749 PQQTGPSMSPH---PSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVP 805 Query: 741 AQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRP-PGPSPHMAQ 799 + GP P M + QM GQ Q P P M G RP PG M Sbjct: 806 SASYSGPGPGMG---ISANNQMHGQGPSQ--PCGAVPLGRMPSAGMQNRPFPGNMSSMTP 860 Query: 800 QHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHG------MSF 853 P + + MP V+ + +QA NSA S G M+ Sbjct: 861 --SSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQA-AANSAQSRQGSFPGMNQSGLMAS 917 Query: 854 NAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANK 913 ++P+S P N S P + +P +VN SA G+ + + + Sbjct: 918 SSPYS-QPMNNSSSLMNTQAPPYS-----MAPAMVN-----SSAASVGLADMMSPGESKL 966 Query: 914 PKKKK----------PPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKL 963 P K P K K S T + E ++P E+ + +D + Sbjct: 967 PLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEP----ERKLWVDRYLTFM 1022 Query: 964 PEFSNRPPGYPSQPVEQRPLQQMPPQL-MQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQ 1022 E + P+ V ++PL + ++ + Q + + +L S Sbjct: 1023 EERGSPVSSLPA--VGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAA 1080 Query: 1023 SQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNP-DSQRMPMQQSGSVPVMVS 1081 S ++Q Q + + + + PP + D+++ P Q S S Sbjct: 1081 SSLKKQYIQYLF----------AFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGS 1130 Query: 1082 LQGPA--------SVPPSPDKQRMPMPVNTP-------LGSNSRKMVYQESPQNPSSSPL 1126 LQGP S+ P + P P +TP G S + + + S S Sbjct: 1131 LQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSF 1190 Query: 1127 AEMASL-PEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPK--PGPSPLSATQGATPQQ 1183 + S+ P A + S+P MP N+ G + PG S TQG P Sbjct: 1191 PKRNSMTPNAPYQQGMSMPDVMGRMP----YEPNKDPFGGMRKVPGSSEPFMTQGQMPNS 1246 Query: 1184 PPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRAS----PRPYYPQTPNNRPPSTEPSEISL 1239 + S N+ R + P AS PY Q P PPS +P Sbjct: 1247 SMQDMYNQSPSGAMSNLG---MGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGH 1303 Query: 1240 SPERLNASIAGLFPPQIN 1257 P GL+P Q N Sbjct: 1304 QP--------GLYPQQPN 1313 Score = 73.2 bits (178), Expect = 3e-12 Identities = 212/1014 (20%), Positives = 334/1014 (32%), Gaps = 138/1014 (13%) Query: 106 ERLRILAQSNNQQLRDLG--ILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEA 163 E L ++ Q L DL I + E ++ A++ + S + + A + A Sbjct: 607 EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHA 666 Query: 164 GFPMASGPGIIRMNNPATVMIPPGGNVS-SSMMAPG--PNPELQPRTPRPASQSDAMDPL 220 ++S PG +P+ V P G N S S ++P P ++ P+ P S+S + L Sbjct: 667 SPHLSSIPG---GPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPAL 723 Query: 221 LSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQ 280 Q++ +G+ +P +Q P+ P Q QQ Sbjct: 724 SQSPMPQERGFMAGT---QRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 780 Query: 281 QQQQQLQARPPQQHQQQQP--QGI-RPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGT 337 Q+ PQ + + P G+ ++ P NQ+ P LG Sbjct: 781 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR 840 Query: 338 MTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQ----- 392 M + G + P PG M + P ++ P PP P +++A +A Q Sbjct: 841 MPS-AGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPP-MPTVNRKAQEAAAAVMQAAANS 898 Query: 393 -MSNPGQFTAPQMKSLQGGPSRVPTPLQQPHL---TNKSPASSPSSFQQGSPASSPTVNQ 448 S G F L S P+ T P S + S AS + Sbjct: 899 AQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADM 958 Query: 449 TQ--QQMGPRPPQNNPLPQGFQQPVSSPGRNP-----------MVQQGNVPPNFMVMQQ- 494 + P P + + +G QP S ++ + + GN P + + + Sbjct: 959 MSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRY 1018 Query: 495 ---QPPNQGPQSLHPGLGGMPKRLPPGF-------SAGQANPNFMQGQVPSTTATTPGNS 544 P S P +G P L + Q N N ++ + +S Sbjct: 1019 LTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSS 1078 Query: 545 GAPQLQANQNVQHAGG------QGAGPPQNQMQV--SHGPPNMMQPSLMG---IHGNMNN 593 A L+ Q +Q+ +G PP + P + PS + G Sbjct: 1079 AASSLK-KQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTP 1137 Query: 594 QQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMI-LSR 652 Q G++ + +V PP+ H Q+ P QG + T++ +P +S Sbjct: 1138 QSTGSNSMAEV-------PGDLKPPTPASTPHGQMTPMQGG---RSSTISVHDPFSDVSD 1187 Query: 653 AQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPM 712 + + M N P Q Q M+ P M G P+ G +V P Sbjct: 1188 SSFPKRNSMTPNAPYQ------QGMSMPDVM----GRMPYEPNKDPFGGMRKVPGSSEPF 1237 Query: 713 IEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQ---GNMVQFTGQMSGQMLPQ 769 + Q G + Q+ N P A G Q G + GQ P Sbjct: 1238 MTQ-------GQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPG 1290 Query: 770 QGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMV 829 QGP + P G + P HM +G PA D+ Q S QQ M Sbjct: 1291 QGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQY----SSQQQEMY 1346 Query: 830 PPHVQAMQGNSASGNHFSGHGMSFNAPFSGA-PNGNQMSCGQNPGFPVNKDVTLTSPLLV 888 + G +SG P G P Q PG + ++ Sbjct: 1347 NQY----------GGSYSGPD---RRPIQGQYPYPYSRERMQGPGQIQTHGIP--PQMMG 1391 Query: 889 NLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPL 948 LQS S G Q N A + P + ++ P G +A PP Sbjct: 1392 GPLQSSSSEG------PQQNMWAARNDMPYPYQNRQG-----------PGGPTQA--PPY 1432 Query: 949 PGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQ 1008 PG +N + + N +PS +++P MQ + PPQP Q P P Sbjct: 1433 PG---MNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSAS-MQPITRPPQPSYQTP-PS 1487 Query: 1009 LPQQ--QQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGP 1060 LP + P P S +S + + + + M+ +P SQ PP P Sbjct: 1488 LPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQP 1541 Score = 49.3 bits (116), Expect = 4e-05 Identities = 89/347 (25%), Positives = 120/347 (34%), Gaps = 40/347 (11%) Query: 145 QDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQ 204 QD+ P GA +++ M G R + P P G S G P L Sbjct: 1249 QDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLY 1308 Query: 205 PRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQ 264 P+ P D M + H + Q N+ + P + Q Sbjct: 1309 PQQPNYKRHMDGM------YGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQ 1362 Query: 265 QQQQQQQQQQQQQQQQQQQ-----QQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWN 319 Q +++ Q Q Q Q+ P Q + PQ + + A +P P Sbjct: 1363 GQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQ--QNMWAARNDMPYPYQNR 1420 Query: 320 QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFG 379 Q P G Q PP G T +P Q++ Q PSH P+ Sbjct: 1421 QGPGGPTQAPPYPGMNRT-------DDMMVP---DQRINHES-----QWPSHVSQRQPYM 1465 Query: 380 SQQAS-QAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQ-QPHLTNK-SPASSPSSFQ 436 S AS Q T PQ P T P SL SR P+P Q L N+ SP+ SP Sbjct: 1466 SSSASMQPITRPPQ---PSYQTPP---SLPNHISRAPSPASFQRSLENRMSPSKSPFLPS 1519 Query: 437 QGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSS-PGRNPMVQQ 482 PTV T Q GP PPQ P+ + P S P+++Q Sbjct: 1520 MKMQKVMPTV-PTSQVTGP-PPQPPPIRREITFPPGSVEASQPVLKQ 1564 Score = 41.2 bits (95), Expect = 0.011 Identities = 94/394 (23%), Positives = 131/394 (33%), Gaps = 50/394 (12%) Query: 1015 PPPPSQPQSQQQQQQQ----QQMMMMLMMQQDPKSVRLPVS-------QNVHPPRGPLNP 1063 PPPPSQPQSQ QQ + + +D + S Q HP P P Sbjct: 389 PPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTP 448 Query: 1064 DSQRMPMQQSGSVPVMV---SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQN 1120 Q S P+++ L G S P S +Q P P + P Sbjct: 449 GPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGS------------YGPPG 496 Query: 1121 PSSSPLAEMASLPEA-SGSEAPSV--PGGPNNMPSHVVLP--QNQLMMTG-PKPGPSPLS 1174 P P+ P A +G + P G + ++P Q ++G + G P Sbjct: 497 PQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYY 556 Query: 1175 ATQGATPQQPP-VNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTE 1233 + Q P PP LPS + P Q + S P P PN+ + Sbjct: 557 SQQPQPPHLPPQAQYLPSQSQQRY----QPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLI 612 Query: 1234 PSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQG--LNPTTLKAIGQAPSNLT 1291 E S L+ SI L P L + + QG NP A +L+ Sbjct: 613 QQERPSSLPDLSGSIDDL-PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLS 671 Query: 1292 MNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRR--SSPGSSRKTTPSPGRQNS 1349 P P + S V QS SG AS S+ PGS +++ P S Sbjct: 672 SIPGG---PSPSPVGSPV--GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQS 726 Query: 1350 KAPK---LTLASQTNAALLQNVELPRNVLVSPTP 1380 P+ +Q N + Q +SP P Sbjct: 727 PMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP 760 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 83.2 bits (204), Expect = 2e-15 Identities = 163/679 (24%), Positives = 229/679 (33%), Gaps = 144/679 (21%) Query: 925 NSQQDLNTPDTRPAGLEEADQPPLP-----GEQGINLDNSGPKLPEFSNRPPGYPSQPVE 979 ++Q D DT+PAG + ++G L+ S E NRP P+ Sbjct: 551 SNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLS 610 Query: 980 QRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMM---- 1035 +P P Q P P PP P P P PPPP QS M + Sbjct: 611 PQPKIVTPYTASQPSPPLPPPPPPPPPPP-PPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669 Query: 1036 ---------------------MLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSG 1074 ++ Q + +P + V PP P P + M Q Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLK 729 Query: 1075 SVPVMVSLQ--------------------GPASVPPSP------DKQRMPMPVNTPLGSN 1108 P SL P + PP P Q P P+ T Sbjct: 730 PAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPT 789 Query: 1109 SRK----MVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMT 1164 S K +V Q +P P + P+ P S P P P LP+ Q Sbjct: 790 STKTVAPVVTQAAPPTP-TPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCA 848 Query: 1165 GPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQT 1224 KP PSPLS PV S+ FP PT + P + P PQ+ Sbjct: 849 --KPPPSPLS----------PVPSVVKQIASQFP--PPPTPPAMESQPLKPVPANVAPQS 894 Query: 1225 PN--NRPPSTEPSEI-----SLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNP 1277 P P +PS I P +S+ PP +P PP P Sbjct: 895 PPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP------------- 941 Query: 1278 TTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSS-PGS 1336 P A+P K S + K S+ G K+ P+ R SS S Sbjct: 942 ----------------PPPTASPTPDKSGSPGKKTSKTSSPGG-KKPPPTPQRNSSIKSS 984 Query: 1337 SRKTTPSPGRQ--NSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNS 1394 S P P R +S K T +++ + + + P A PP PG N S Sbjct: 985 SGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETL----------PPPAAPPKPGKL-NLS 1033 Query: 1395 GLN----PQNSTVSVAA--VGGVVEDN-KESLNVPQDSDCQNSQSRKE--QVNIELKAV- 1444 G+N Q VS A + G +D+ E + P DSD E IE+ AV Sbjct: 1034 GVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVF 1093 Query: 1445 ---PAQEVKMVVPEDQ--SKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQL--LDN 1497 + +V +V P+ Q SK + + P P ++ L + E PT + + + Sbjct: 1094 SGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPT 1153 Query: 1498 SGAPNVTIKPPGLTDLEVT 1516 S +++++P L DL T Sbjct: 1154 SPKSSLSVQPGFLADLNRT 1172 Score = 67.4 bits (163), Expect = 1e-10 Identities = 171/797 (21%), Positives = 262/797 (32%), Gaps = 143/797 (17%) Query: 112 AQSNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGP 171 +QSN+ D G+ Q G ++ S+ + + + RME+ Sbjct: 546 SQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMES-------- 597 Query: 172 GIIRMNNPATVMIPPGG---NVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQ 228 MN P T ++PP + + A P+P L P P P P L Sbjct: 598 ----MNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPL--PS 651 Query: 229 QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQA 288 QS PS A P + + +LQ Q + Q Q + Q Sbjct: 652 QSAPSAGSAAPMF----------VKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQI 701 Query: 289 RPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAP 348 P P G+ P P P PP L+P P SL +A P Sbjct: 702 LVP-------PNGVVP----PPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSA-------P 743 Query: 349 LPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQ 408 P Q+Q +A P PP P P Q + P ++ + AP + Q Sbjct: 744 PPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTST-KTVAPVVT--Q 800 Query: 409 GGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGF- 467 P PTP K PA P+S+ SP + P P PP P Q F Sbjct: 801 AAP---PTPTPPVPPAKKQPAF-PASYIPPSPPTPPV---------PVPPPTLPKQQSFC 847 Query: 468 -QQPVSSPGRNPMV-----QQGNVPPNFMVMQQQP-----PNQGPQSLHPGLGGMPKRLP 516 + P S P V Q PP M+ QP N PQS P + PK P Sbjct: 848 AKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQS-PPAVKAKPKWQP 906 Query: 517 -------PGFSAGQANPNFM------------QGQVPSTTATTPGNSGAPQLQANQNVQH 557 P F + + P T + TP SG+P + ++ Sbjct: 907 SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSP 966 Query: 558 AGGQGAGPPQNQMQVSHGP----PNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQP 613 G + PQ + P +PS+ + SG P P Sbjct: 967 GGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFT--PPAESGSPSKETLPPPAAP 1024 Query: 614 QQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPS 673 + L G++ +P V QQG ++ + P++ R + +PPS + P Sbjct: 1025 PKPGKLNLSGVN---LPG----VLQQGCVSAKAPVLSGRGK--DSVVEFPSPPSDSDFPP 1075 Query: 674 PQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQ 733 P PP+ L ++ A + P+ V+ NP +Q ++ + Sbjct: 1076 P----PPETELPLPPIEIPAVFSGNTSPKVAVV---NPQPQQWSKMSVKKAPPPTRPKRN 1128 Query: 734 SNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGP 793 + A+I PT ++PQ V SP + +Q PG Sbjct: 1129 DSTRLTQAEISEQPT--------------MATVVPQ---VPTSPKSSLSVQ------PGF 1165 Query: 794 SPHMAQQHGDPATTANNDVS--LSQMMPDVSIQQTNMVPPHVQAM---QGNSASGNHFSG 848 + + + T + +S +S+ P ++ + PP + + Q G+H SG Sbjct: 1166 LADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISG 1225 Query: 849 HGMSFNAPFSGAPNGNQ 865 + P P +Q Sbjct: 1226 YATLRRGPPPAPPKRDQ 1242 Score = 42.4 bits (98), Expect = 0.005 Identities = 48/192 (25%), Positives = 77/192 (40%), Gaps = 17/192 (8%) Query: 914 PKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGY 973 P PP+ K + +N P G A P L G +G + P P S+ PP Sbjct: 1019 PPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSG-RGKDSVVEFPSPPSDSDFPPPP 1077 Query: 974 PSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQ-QQPPPPSQPQSQQ-----QQ 1027 P + P+ ++P + +P QPQ ++ PPP++P+ Q Sbjct: 1078 PETELPLPPI-EIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQA 1136 Query: 1028 QQQQQMMMMLMMQQDPKSVRLPVSQNVHPP-RGPLNPDSQRMPMQQSGSVPVMVSLQGPA 1086 + +Q M ++ Q P S + +S V P LN QR + + GS+ +S P Sbjct: 1137 EISEQPTMATVVPQVPTSPKSSLS--VQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPT 1194 Query: 1087 ------SVPPSP 1092 ++PP P Sbjct: 1195 ATMDDMALPPPP 1206 Score = 36.6 bits (83), Expect = 0.26 Identities = 61/286 (21%), Positives = 95/286 (33%), Gaps = 41/286 (14%) Query: 1539 SSKEPSNSLNLPHSNELCSSLVHPELSE--VSSNVAPSIPPVMSRPVSSSSISTPLPPNQ 1596 SSK S+N P+++ + P++ +S +P +PP P P PP Sbjct: 590 SSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPL 649 Query: 1597 ITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNA----GSKVMVSEGQSAAQSNAR 1652 P ++ + +A P ++ ST+ + NA G+ + + Sbjct: 650 --------PSQSAPSAGSAAPMFVK---YSTITRLQNASQHSGALFKPPTPPVMQSQSVK 698 Query: 1653 PQFITPVFINSSSIIQVMKGSQP-----------STIPAAPLTTNSGLMPPSVAVVGPLH 1701 PQ + P + ++ P P AP PP + + H Sbjct: 699 PQILVP----PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQH 754 Query: 1702 IPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQ 1761 I Q + P PP +P P +PLV T + +P T + PPV Sbjct: 755 ITQVAPPTPPPPPP---IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVP 811 Query: 1762 QVKELNPDEAS------PQVNTSADQNTLPSSQSTTMVSPLLTNSP 1801 K+ AS P TLP QS P SP Sbjct: 812 PAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSP 857 Score = 35.0 bits (79), Expect = 0.76 Identities = 114/529 (21%), Positives = 171/529 (32%), Gaps = 111/529 (20%) Query: 1349 SKAPKLTLASQTNAAL--------LQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQN 1400 S +L ASQ + AL +Q+ + +LV P + PP P P G Sbjct: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG----- 722 Query: 1401 STVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKK 1460 ++ + + C S + LK Q + V P Sbjct: 723 ----------------SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP 766 Query: 1461 DGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTI------KPPGLTDLE 1514 P P LP K LV+ + +++ ++ + P T K P Sbjct: 767 ---PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASY 823 Query: 1515 VTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPE----------L 1564 + P + +P Q + PS +P + +S P L Sbjct: 824 IPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPL 883 Query: 1565 SEVSSNVAPSIPPVM---------SRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAA 1615 V +NVAP PP + S PV S P PP VF P A Sbjct: 884 KPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPP-PPESSLVFPPPPPSPVPAPPPPP 942 Query: 1616 LPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQP 1675 PT T + G K + + PQ + I SSS + + +P Sbjct: 943 PPT-----ASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS--IKSSSGAEHPEPKRP 995 Query: 1676 S--------TIPAAPLTTNSGLMPPSVAVVGP-------LHIP----QNIKFSSAPV--- 1713 S T PA + + +PP A P +++P Q + APV Sbjct: 996 SVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSG 1055 Query: 1714 ----------PPNALSSSPAPNIQTGRPLVLSSRATPVQLPS--PPCTSSPVVPSHPPVQ 1761 P + S P P +T PL P+++P+ TS V +P Q Sbjct: 1056 RGKDSVVEFPSPPSDSDFPPPPPETELPL------PPIEIPAVFSGNTSPKVAVVNPQPQ 1109 Query: 1762 QVKELN----PDEASPQVNTSADQNTLPSSQSTTM--VSPLLTNSPGSS 1804 Q +++ P P+ N S S+ TM V P + SP SS Sbjct: 1110 QWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSS 1158 >gi|119943102 CREB binding protein isoform b [Homo sapiens] Length = 2404 Score = 82.4 bits (202), Expect = 4e-15 Identities = 155/575 (26%), Positives = 213/575 (37%), Gaps = 82/575 (14%) Query: 270 QQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTA-----PTQVPVPPGWNQLPSG 324 +QQQ Q + QQ Q ++ R + + PQ P T+ PTQ P P Q P Sbjct: 1813 RQQQIQ--HRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTP---QTPQP 1867 Query: 325 ALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPP--PYPFGSQQ 382 QP P+ S+ + G+ P +P T Q P+ PPP P P + Sbjct: 1868 PAQPQPSPVSM----SPAGFPSVARTQPPTTVSTGKP---TSQVPAPPPPAQPPPAAVEA 1920 Query: 383 ASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPAS--SPSSFQQGSP 440 A Q Q + + S+ G + + TP Q +P S P Q P Sbjct: 1921 ARQIEREAQQQQH--LYRVNINNSMPPGRTGMGTPGSQ-----MAPVSLNVPRPNQVSGP 1973 Query: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQG 500 P++ Q Q P PQ P+P G +PV S M Q V M Q P + Sbjct: 1974 V-MPSMPPGQWQQAPL-PQQQPMP-GLPRPVIS-----MQAQAAVAGPRMPSVQPPRSIS 2025 Query: 501 PQSLHPGLGGM-----PKRLPPGFSAGQANPNFMQGQVPSTT----ATTPGNSGAPQLQA 551 P +L L + P++ + ++NP M + T A PG P LQ+ Sbjct: 2026 PSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQS 2085 Query: 552 NQNVQHAGGQGAGPP-QNQMQVSHGPPNMMQPSLMGIHGNMNNQ-QAGTSGVP--QVNLS 607 +Q G P QN + G P P G +N Q QA P N++ Sbjct: 2086 QPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMA 2145 Query: 608 NMQGQPQQGPPSQLM-GMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPP 666 +M Q ++ QL+ QQ Q Q QQQG+ M PQG P Sbjct: 2146 SMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPA 2205 Query: 667 SQNLGPSPQRMTPPKQMLSQQGPQM--MAPHNQMMGPQGQVLL--QQNPMIEQIMTN--- 719 Q QRM +Q L QG M MA +G GQ L P I+Q + Sbjct: 2206 MQ----QQQRM---QQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRIL 2258 Query: 720 QMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQM---------LPQQ 770 Q Q KQQ + Q N M ++ G Q +S Q+ PQ Sbjct: 2259 QQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQS 2318 Query: 771 GPVNNSPSQVMGIQGQVLRPPGPSP-HMAQQHGDP 804 P ++SPS + P PSP H++ Q G P Sbjct: 2319 QPPHSSPSPRI--------QPQPSPHHVSPQTGSP 2345 Score = 79.3 bits (194), Expect = 4e-14 Identities = 99/345 (28%), Positives = 130/345 (37%), Gaps = 48/345 (13%) Query: 183 MIPPGGNVSSSMMAPGPNPELQPRTPR-PASQSDAMDPLLSGLHIQQQS----HPSGS-- 235 M P G S M P P QP A Q+ P G+ QQQ+ +P G Sbjct: 2077 MQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRP---GVPPQQQAMGGLNPQGQAL 2133 Query: 236 --LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQ--LQARPP 291 + P H+P MNP L++Q QQQQQQQQQQQQQQQQQQ + Sbjct: 2134 NIMNPGHNPNMA-----SMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMA 2188 Query: 292 QQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPG 351 Q QQPQG PP Q P S+G M A G Sbjct: 2189 GHGQFQQPQG---------PGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMG-------- 2231 Query: 352 PMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFT--APQMKSLQG 409 Q +P L TP+ Q+ Q Q+ +PGQ +PQ L G Sbjct: 2232 --QLGQMGQPGLGADSTPNIQQAL----QQRILQQQQMKQQIGSPGQPNPMSPQQHMLSG 2285 Query: 410 GPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQ-GFQ 468 P P QQ + + SP+ Q P S P + ++ P+P ++ PQ G Sbjct: 2286 QPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSP 2345 Query: 469 QPVSSPGRNPMVQQ---GNVPPNFMVMQQQPPNQGPQSLHPGLGG 510 P + + Q GN + M+ Q P++ S L G Sbjct: 2346 HPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVG 2390 Score = 78.6 bits (192), Expect = 6e-14 Identities = 217/952 (22%), Positives = 332/952 (34%), Gaps = 185/952 (19%) Query: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQG 500 ASSP Q +P N +S+ G++P+ Q + P+ + +Q G Sbjct: 91 ASSPVQQGLGGQAQGQPNSAN------MASLSAMGKSPLSQGDSSAPS--LPKQAASTSG 142 Query: 501 P-----QSLHPGLG---GMPKRLPPGFSAGQA---NPNFMQGQVPSTTATTPGNS---GA 546 P Q+L+P G+ P G N NF Q P + G+S A Sbjct: 143 PTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTH-PGLLNSNSGHSLINQA 201 Query: 547 PQLQA---NQNVQHAG-GQGAGPPQNQMQVSHGPPNMMQPSLMGI------HGNMNNQQA 596 Q QA N ++ AG G+GAG P + +++ +L + H +N QA Sbjct: 202 SQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQA 261 Query: 597 GTSGVPQVNLSNMQ---GQPQQ---GPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMIL 650 G G+ ++ ++ GQP G P G++ Q+ Q MV T P + Sbjct: 262 G--GMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQS-MVNSLPTF-PTDIKNT 317 Query: 651 SRAQLMPQGQMMVNP---PSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLL 707 S + QM + P+Q + P ++++ QQ ++ H + Q Sbjct: 318 SVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAH------KCQRRE 371 Query: 708 QQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQF-TGQMSGQM 766 Q N + + K N I+ P +Q + TGQ + Sbjct: 372 QANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQAILGSPASGIQNTIGSVGTGQQNATS 431 Query: 767 LPQQGPVNNSPSQ----VMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVS 822 L P++ S Q +G+ P+M Q +Q+ P V Sbjct: 432 LSNPNPIDPSSMQRAYAALGL-----------PYMNQPQ-------------TQLQPQVP 467 Query: 823 IQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTL 882 QQ H Q N N N P G ++ Q P +++ Sbjct: 468 GQQPAQPQTHQQMRTLNPLGNN-------PMNIPAGG------ITTDQQPPNLISESALP 514 Query: 883 TSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKK-KNSQQDLNTPDTRPAGLE 941 TS N L +D G N+ T + P P + + T D R + Sbjct: 515 TSLGATNPLMND------GSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVH 568 Query: 942 EADQPPLPGEQGINL-DNSGPKLPEFSNRPPG--YPS-------------------QPVE 979 + Q P L D L ++ + G Y S + +E Sbjct: 569 KLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELE 628 Query: 980 QRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMM 1039 ++ ++ Q + P P QP P +PQ Q PP+ P S + Q M Sbjct: 629 EKRRSRLHKQGILGNQPALPAPGAQP-PVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFN 687 Query: 1040 QQDPKSVRLPVSQNVHPPRGP--LNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRM 1097 +V+LP P GP +P + + M GSVP M ++ PS RM Sbjct: 688 PMSLGNVQLP-----QAPMGPRAASPMNHSVQMNSMGSVPGM-------AISPS----RM 731 Query: 1098 PMPVNTPLGSNSRKMVYQES------PQN--PSSSPLAE--MASLPEASGSEAPSVPGGP 1147 P P N +G+++ M+ Q PQN PSSS M P +G VPG Sbjct: 732 PQPPNM-MGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAA 790 Query: 1148 NNMPSHVVLPQNQLMMTGP------KPGPSPLSATQGATPQQ---PPVNSLPSSHGHHFP 1198 P +++ PQ + P P P P S G Q PP G P Sbjct: 791 LPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPP--------GMTPP 842 Query: 1199 NVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINI 1258 AAPTQ S P + + +P P TP + P +T+ + S + A+ PQ Sbjct: 843 QPAAPTQPSTPVSSSGQTPTP----TPGSVPSATQ----TQSTPTVQAAAQAQVTPQPQT 894 Query: 1259 PLPPRPNLNRGFDQQGLNP-------TTLKAIGQAPSNLTMNPSNFATPQTH 1303 P+ P QQ P T L + N PS+ A+ +T+ Sbjct: 895 PVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETN 946 Score = 78.6 bits (192), Expect = 6e-14 Identities = 139/552 (25%), Positives = 184/552 (33%), Gaps = 119/552 (21%) Query: 225 HIQQQSHPSGSLAPPHHPMQPVSVNR-------------QMNPANFPQLQQQQ------- 264 ++ QQS PS + APP P Q S + M+PA FP + + Q Sbjct: 1838 NVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVST 1897 Query: 265 ---------------------QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIR 303 + +Q +++ QQQQ + + PP + G Sbjct: 1898 GKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPP----GRTGMGTP 1953 Query: 304 PQFTAPTQVPVPPGWNQLPSGALQP--PPAQGSLGTMTANQGWKKAPLPGPMQQQLQARP 361 AP + VP NQ+ SG + P PP Q W++APLP Q Q P Sbjct: 1954 GSQMAPVSLNVPRP-NQV-SGPVMPSMPPGQ-----------WQQAPLP-----QQQPMP 1995 Query: 362 SLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQP 421 L P P S QA A P+M S+Q S P+ LQ Sbjct: 1996 GL-----------PRPVISMQAQAA------------VAGPRMPSVQPPRSISPSALQDL 2032 Query: 422 HLTNKSPASSPSSFQQ-------GSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSP 474 T KSP SSP QQ + + Q + P P P QP P Sbjct: 2033 LRTLKSP-SSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQP 2091 Query: 475 GRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKR------LPPGFSAGQA--NP 526 P + Q N MQ P G +GG+ + + PG + A NP Sbjct: 2092 --QPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNP 2149 Query: 527 NFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHG----PPNMMQP 582 + + Q Q Q AG G Q Q G PP M Q Sbjct: 2150 QYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQ 2209 Query: 583 SLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPS--QLMGMHQQIVPSQGQMVQQQG 640 M H + G L M GQP G S + QQ + Q QM QQ G Sbjct: 2210 QRMQQHLPLQGSSMGQMAAQMGQLGQM-GQPGLGADSTPNIQQALQQRILQQQQMKQQIG 2268 Query: 641 TLNPQNPMILSRAQLMPQGQMMVNP-PSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMM 699 + NPM S Q M GQ + P Q + S + PQ PH+ Sbjct: 2269 SPGQPNPM--SPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHS--- 2323 Query: 700 GPQGQVLLQQNP 711 P ++ Q +P Sbjct: 2324 SPSPRIQPQPSP 2335 Score = 72.8 bits (177), Expect = 3e-12 Identities = 154/601 (25%), Positives = 212/601 (35%), Gaps = 93/601 (15%) Query: 381 QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQ----QPHLTNKSPASSPSSFQ 436 + A+ N PQ S P +AP Q PS TP QP + SPA PS + Sbjct: 1830 RMATMNTRNVPQQSLPSPTSAPPGTPTQQ-PSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888 Query: 437 QGSPASSPTVNQTQQQMGPRPPQ----------------------------NNPLPQGFQ 468 P + T T Q P PP NN +P G + Sbjct: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPG-R 1947 Query: 469 QPVSSPGRNPMVQQGNVP-PNFM---VMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQA 524 + +PG NVP PN + VM PP Q Q+ P MP LP + QA Sbjct: 1948 TGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMP-GLPRPVISMQA 2006 Query: 525 NPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQ--MQVSHGPPNMMQP 582 ++PS P S +P A Q++ + P Q Q + + P +M Sbjct: 2007 QAAVAGPRMPS---VQPPRSISP--SALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAA 2061 Query: 583 SLMGIHGNMNNQQAGTSGVPQVNLSNMQG-QPQQG----PPSQLMGMHQQIVPSQGQMVQ 637 + Q G PQ L + G QPQ G P Q + Q VP G Q Sbjct: 2062 FIKQRTAKYVANQPGMQ--PQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQ 2119 Query: 638 QQ--GTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPH 695 QQ G LNPQ + +M G NP ++ P + M +Q+L QQ Q Sbjct: 2120 QQAMGGLNPQGQAL----NIMNPGH---NPNMASMNPQYREML-RRQLLQQQQQQQQQQQ 2171 Query: 696 NQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPG--PAQIMRGPTPNMQG 753 Q QG M M G+ Q Q P Q M+ P Sbjct: 2172 QQQQQQQGSA----------GMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGS 2221 Query: 754 NMVQFTGQMS--GQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANND 811 +M Q QM GQM +++P+ +Q ++L+ M QQ G P N Sbjct: 2222 SMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQ----QQQMKQQIGSPGQP--NP 2275 Query: 812 VSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQN 871 +S Q M Q +++ + S S S + P S P+ + Q Sbjct: 2276 MSPQQHMLSGQPQASHLPGQQI----ATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQP 2331 Query: 872 PGFP--VNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQD 929 P V+ P L + S I GH G N +Q +A P+ P R +S+ Sbjct: 2332 QPSPHHVSPQTGSPHPGLAVTMASSIDQGHLG-NPEQ---SAMLPQLNTPSRSALSSELS 2387 Query: 930 L 930 L Sbjct: 2388 L 2388 Score = 65.9 bits (159), Expect = 4e-10 Identities = 116/530 (21%), Positives = 168/530 (31%), Gaps = 113/530 (21%) Query: 235 SLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQH 294 SL+ P+ P+ P S+ R P + Q Q Q Q Q QQ Q Q QQ P + Sbjct: 431 SLSNPN-PIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNN 489 Query: 295 QQ----------QQPQGIRPQFTAPTQVPVP-----PGWNQLPSGALQPPPAQGSLGTMT 339 QQP + + PT + G N G L P + Sbjct: 490 PMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTG 549 Query: 340 ANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQ-------ASQAHTNFPQ 392 +GW + + Q L++ VQ P P ++ A + + + Sbjct: 550 VRKGWHEH-----VTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYE 604 Query: 393 MSNPGQ----FTAPQMKSLQ-----------------GGPSRVPTPLQQPHLTNKSPASS 431 +N A ++ +Q G +P P QP + ++ Sbjct: 605 SANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVR 664 Query: 432 PSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNV------ 485 P + P + V+Q P N LPQ P ++ N VQ ++ Sbjct: 665 PPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGM 724 Query: 486 ---------PPNFMV-----MQQQPPNQG---PQSLHPGLGGMPKRLPPGFSAGQANPNF 528 PPN M M Q P Q PQ+ P G + G A Sbjct: 725 AISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGA---MSVGMGQPPAQTGV 781 Query: 529 MQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIH 588 QGQVP P N PQ Q PP Q + PP Sbjct: 782 SQGQVPGAALPNPLNMLGPQ----------ASQLPCPPVTQSPLHPTPP----------- 820 Query: 589 GNMNNQQAGTSGVPQVNLSNMQGQ--PQQGPPSQ----LMGMHQQIVPSQGQMVQQQGTL 642 + +G+P + + G PQ P+Q + Q P+ G + T Sbjct: 821 -----PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQ 875 Query: 643 NPQNPMILSRAQLMPQGQMMVNPP------SQNLGPSPQRMTPPKQMLSQ 686 + ++AQ+ PQ Q V PP S P+P PP LSQ Sbjct: 876 STPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQ 925 Score = 62.8 bits (151), Expect = 3e-09 Identities = 126/475 (26%), Positives = 165/475 (34%), Gaps = 79/475 (16%) Query: 128 QIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMA----SGPGIIRMNNPATVM 183 QIE E A Q V +N M G + G MA + P +++ P Sbjct: 1923 QIERE-----AQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPS 1977 Query: 184 IPPGGNVSSSMMAPGPNPELQPRTPRPA----SQSDAMDPLLSGLHIQQQSHPSG----- 234 +PPG AP P + P PRP +Q+ P + + + PS Sbjct: 1978 MPPG----QWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLL 2033 Query: 235 -SLAPPHHPMQPVSVNR--QMNP---------------ANFPQLQQQQQQQQQQQQQQQ- 275 +L P P Q V + NP AN P +Q Q Q Q Q Q Sbjct: 2034 RTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQP 2093 Query: 276 ---QQQQQQQQQQLQA---RPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPP 329 QQ Q +QA RP QQQ G+ PQ A + PG N P+ A P Sbjct: 2094 GMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALN--IMNPGHN--PNMASMNP 2149 Query: 330 PAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLA-------TVQTPSHPPPPYPFGSQQ 382 + L Q ++ QQQ Q +A Q P P YP QQ Sbjct: 2150 QYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQP-QGPGGYPPAMQQ 2208 Query: 383 ASQAHTNFP-QMSNPGQFTAPQMKSL----QGGPSRVPTPLQQPHLTNKSPASSPSSFQQ 437 + + P Q S+ GQ A QM L Q G TP Q L + Q Sbjct: 2209 QQRMQQHLPLQGSSMGQMAA-QMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQI 2267 Query: 438 GSPASSPTVNQTQQQMGPRPPQNNPLP-QGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQP 496 GSP P QQ M PQ + LP Q +S+ R+P Q P Q QP Sbjct: 2268 GSP-GQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRP------QSQP 2320 Query: 497 PNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQA 551 P+ P P + P G +P V ++ G+ G P+ A Sbjct: 2321 PHSSPS---PRIQPQPSPHHVSPQTGSPHPGL---AVTMASSIDQGHLGNPEQSA 2369 Score = 60.8 bits (146), Expect = 1e-08 Identities = 141/596 (23%), Positives = 203/596 (34%), Gaps = 97/596 (16%) Query: 720 QMQGNKQQFNTQNQSNV----MPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNN 775 Q Q +++ T N NV +P P G TP Q + Q T Q Q PQ PV+ Sbjct: 1823 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPG-TPTQQPSTPQ-TPQPPAQ--PQPSPVSM 1878 Query: 776 SPS---QVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPH 832 SP+ V Q G PA V ++ + + QQ ++ + Sbjct: 1879 SPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVN 1938 Query: 833 VQAMQGNSASGNHFSGHGMSFNAPFS-GAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLL 891 + +G G M AP S P NQ+S P P + +PL Sbjct: 1939 INNSMPPGRTGMGTPGSQM---APVSLNVPRPNQVSGPVMPSMPPGQ--WQQAPLPQQQP 1993 Query: 892 QSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGE 951 + + + P + P ++ QDL P+ P + Sbjct: 1994 MPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSS-------PQQQQ 2046 Query: 952 QGINLDNSGPKLPE----------FSNRP-----PGYPSQP-------VEQRPLQQMPPQ 989 Q +N+ S P+L +N+P PG SQP + Q+P Q Sbjct: 2047 QVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNA 2106 Query: 990 LMQHVAPPPQPPQQQ------PQ-------------------PQLPQQQQPPPPSQPQSQ 1024 + V P PPQQQ PQ PQ + + Q Q Q Sbjct: 2107 MQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQ 2166 Query: 1025 QQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPP-RGPLNPDSQRMPMQQSGSVPVMVSLQ 1083 QQQQQQQQ QQ S + H + P P MQQ + + LQ Sbjct: 2167 QQQQQQQQ-------QQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQ 2219 Query: 1084 GPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSV 1143 G + + ++ LG++S + Q Q + + + + GS Sbjct: 2220 GSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQR-----ILQQQQMKQQIGS----- 2269 Query: 1144 PGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAP 1203 PG PN M PQ Q M++G +P S L Q AT V S P+ P P Sbjct: 2270 PGQPNPMS-----PQ-QHMLSG-QPQASHLPGQQIATSLSNQVRS-PAPVQSPRPQSQPP 2321 Query: 1204 TQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIP 1259 + P+ + SP PQT + P S+ L PQ+N P Sbjct: 2322 HSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTP 2377 Score = 49.3 bits (116), Expect = 4e-05 Identities = 144/657 (21%), Positives = 210/657 (31%), Gaps = 145/657 (22%) Query: 559 GGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPP 618 G G G QN +S+ PN + PS M + G+P +N Q QPQ P Sbjct: 420 GSVGTGQ-QNATSLSN--PNPIDPSSM-------QRAYAALGLPYMNQPQTQLQPQV--P 467 Query: 619 SQLMGMHQQIVPSQGQMVQQQGTLNP--QNPMILSRAQLMPQGQMMVNPPSQNLGPSPQR 676 Q P+Q Q QQ TLNP NPM N P+ + Q Sbjct: 468 GQQ--------PAQPQTHQQMRTLNPLGNNPM---------------NIPAGGITTDQQ- 503 Query: 677 MTPPKQMLSQQGPQMMAPHNQMMGP---QGQV-LLQQNPMIEQIMTNQMQGNKQQFNTQN 732 PP + P + N +M G + L P + ++ + TQ+ Sbjct: 504 --PPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQD 561 Query: 733 QSNVMPGPAQIMRGPTPNMQG-------NMVQFTGQMSGQM------------------- 766 + + PTP+ N+V + ++ G M Sbjct: 562 LRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIY 621 Query: 767 -------------LPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVS 813 L +QG + N P+ L PG P + Q P N +S Sbjct: 622 KIQKELEEKRRSRLHKQGILGNQPA---------LPAPGAQPPVIPQ-AQPVRPPNGPLS 671 Query: 814 LSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPG 873 L VS + P + +Q A G +P + + N M G PG Sbjct: 672 LPVNRMQVSQGMNSFNPMSLGNVQLPQAP------MGPRAASPMNHSVQMNSM--GSVPG 723 Query: 874 FPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKK--PPRKKKNSQQDLN 931 ++ P ++ NN A P + + P + +S ++ Sbjct: 724 MAISPSRMPQPPNMMGA--------------HTNNMMAQAPAQSQFLPQNQFPSSSGAMS 769 Query: 932 TPDTRPAGLEEADQPPLPGEQGIN-LDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQL 990 +P Q +PG N L+ GP+ + P PV Q PL PP Sbjct: 770 VGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQL-------PCPPVTQSPLHPTPPPA 822 Query: 991 --------MQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQD 1042 +QH PP P PQP P QP P Q + Q Sbjct: 823 STAAGMPSLQHTTPPGMTP---PQPAAP--TQPSTPVSSSGQTPTPTPGSVPSATQTQST 877 Query: 1043 PKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVN 1102 P +Q P+ P+ P S P Q S P V Q P P S + V Sbjct: 878 PTVQAAAQAQVTPQPQTPVQPPSVATP-QSSQQQPTPVHAQ-PPGTPLSQAAASIDNRVP 935 Query: 1103 TPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQN 1159 TP +S S Q P+ EM + +A +E PG P ++ ++ Sbjct: 936 TP---SSVASAETNSQQPGPDVPVLEMKTETQAEDTEPD--PGESKGEPRSEMMEED 987 Score = 48.9 bits (115), Expect = 5e-05 Identities = 85/345 (24%), Positives = 118/345 (34%), Gaps = 67/345 (19%) Query: 982 PLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQ 1041 P Q +P APP P QQ PQ PQ PP+QPQ + Q Sbjct: 1840 PQQSLPSPTS---APPGTPTQQPSTPQTPQ-----PPAQPQPSPVSMSPAGFPSVARTQP 1891 Query: 1042 DPK-SVRLPVSQNVHPPRGPLNPDS--------QRMPMQQSGSVPVMVSLQGPASVPP-- 1090 S P SQ PP P + +R QQ V ++ S+PP Sbjct: 1892 PTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNIN----NSMPPGR 1947 Query: 1091 ----SPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGG 1146 +P Q P+ +N P N S P+ M S+P +AP Sbjct: 1948 TGMGTPGSQMAPVSLNVP-------------RPNQVSGPV--MPSMPPGQWQQAPLPQQQ 1992 Query: 1147 P-NNMPSHVVLPQNQLMMTGPK-PGPSP---------------LSATQGATPQQPPVNSL 1189 P +P V+ Q Q + GP+ P P L + QQ +N L Sbjct: 1993 PMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNIL 2052 Query: 1190 PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIA 1249 S+ + T P P+P P +P + SL + LNA A Sbjct: 2053 KSNPQLMAAFIKQRTAKYVANQPG-MQPQPGLQSQPGMQPQPGMHQQPSL--QNLNAMQA 2109 Query: 1250 GLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNP 1294 G+ P + PP+ G + QG + G P+ +MNP Sbjct: 2110 GVPRPGV----PPQQQAMGGLNPQG-QALNIMNPGHNPNMASMNP 2149 Score = 48.5 bits (114), Expect = 7e-05 Identities = 93/431 (21%), Positives = 147/431 (34%), Gaps = 82/431 (19%) Query: 1126 LAEMASLPEASGSEAPSVPGGPNNMPSH--VVLPQNQLMMTGPKPGPSPLSATQGATPQQ 1183 L +LP A G++ P +P P + + LP N++ ++ +P+S PQ Sbjct: 641 LGNQPALP-APGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQA 699 Query: 1184 P--PVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPN------NRPPSTEPS 1235 P P + P +H + S P A PQ PN N + P+ Sbjct: 700 PMGPRAASPMNH--------SVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPA 751 Query: 1236 EISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPS 1295 + P+ S +G + + PP Q G++ GQ P NP Sbjct: 752 QSQFLPQNQFPSSSGAM--SVGMGQPPA--------QTGVSQ------GQVPGAALPNPL 795 Query: 1296 NFATPQTHKLDSVVVNSGKQSNS---GATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAP 1352 N PQ +L V + +T PS + PG T P P + Sbjct: 796 NMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPG---MTPPQPAAPTQPST 852 Query: 1353 KLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVV 1412 ++ + QT PT P PGS P ++ TV AA V Sbjct: 853 PVSSSGQT-----------------PT-----PTPGSVP-SATQTQSTPTVQAAAQAQVT 889 Query: 1413 EDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPS 1472 + + P + Q+SQ + V+ + P + + D + P+ + S Sbjct: 890 PQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASI-------DNRVPTPSSVAS 942 Query: 1473 VEENKNLVSP--AMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASV 1530 E N P + E T +Q D P + P +E EDL+ AS Sbjct: 943 AETNSQQPGPDVPVLEMKTE-TQAEDTEPDPGESKGEPRSEMME--------EDLQGASQ 993 Query: 1531 IPTLQDLSSSK 1541 + D++ K Sbjct: 994 VKEETDIAEQK 1004 Score = 43.5 bits (101), Expect = 0.002 Identities = 84/390 (21%), Positives = 120/390 (30%), Gaps = 73/390 (18%) Query: 204 QPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQ 263 QP P P +Q + Q P+G L+ P + MQ NP + +Q Sbjct: 644 QPALPAPGAQPPVIP------QAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP 697 Query: 264 QQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPS 323 Q + A P H Q + PG PS Sbjct: 698 QAPMGPR-----------------AASPMNHSVQM-----------NSMGSVPGMAISPS 729 Query: 324 GALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQA 383 QPP G+ N +AP Q Q PS + + PP G Q Sbjct: 730 RMPQPPNMMGA----HTNNMMAQAPAQSQFLPQNQF-PSSSGAMSVGMGQPPAQTGVSQG 784 Query: 384 SQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASS 443 P NP PQ L P Q P PAS+ + + Sbjct: 785 QVPGAALP---NPLNMLGPQASQLP-----CPPVTQSPLHPTPPPASTAAGMPSLQHTTP 836 Query: 444 PTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQS 503 P + Q +P + P+ Q P +PG P Q P Q PQ+ Sbjct: 837 PGMTPPQPAAPTQP--STPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQT 894 Query: 504 -LHPGLGGMPK----------RLPPGFSAGQANPNF-MQGQVPSTTATTPGNSGAP---- 547 + P P+ PPG QA + + PS+ A+ NS P Sbjct: 895 PVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDV 954 Query: 548 -------QLQANQNVQHAGGQGAGPPQNQM 570 + QA ++ + G+ G P+++M Sbjct: 955 PVLEMKTETQA-EDTEPDPGESKGEPRSEM 983 Score = 42.0 bits (97), Expect = 0.006 Identities = 74/332 (22%), Positives = 123/332 (37%), Gaps = 44/332 (13%) Query: 1576 PPVM--SRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPN 1633 PPV+ ++PV + LP N++ V N + + LP A M P Sbjct: 654 PPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP----QAPMGPRAASPM 709 Query: 1634 AGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGS--QPSTIPAAPLTTNSGLMP 1691 S M S G + + + P + + +M + Q +P ++SG M Sbjct: 710 NHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMS 769 Query: 1692 PSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPL-VLSSRATPVQLPSPPCTS 1750 VG P S VP AL PN PL +L +A+ QLP PP T Sbjct: 770 -----VGMGQPPAQTGVSQGQVPGAAL-----PN-----PLNMLGPQAS--QLPCPPVTQ 812 Query: 1751 SPVVPSHPP------VQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSS 1804 SP+ P+ PP + ++ P +P + Q + P S S +P + P ++ Sbjct: 813 SPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSAT 872 Query: 1805 GNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGL 1864 + +P + + +V Q T + + ++Q + PG Sbjct: 873 QTQSTPTVQAAAQAQVTPQPQ---TPVQPPSVATPQSSQQQ--------PTPVHAQPPG- 920 Query: 1865 MGTEQLSTELDSKTPTPPAPTLLKMTSSPVGP 1896 Q + +D++ PTP + + S GP Sbjct: 921 TPLSQAAASIDNRVPTPSSVASAETNSQQPGP 952 Score = 40.8 bits (94), Expect = 0.014 Identities = 195/971 (20%), Positives = 312/971 (32%), Gaps = 140/971 (14%) Query: 734 SNVMPGPAQIMRGPTPNMQGNMVQFTGQ-----MSGQMLPQQGPVNNSPSQVMGIQGQVL 788 S++ PG + +P QG Q GQ M+ + P++ S + Q Sbjct: 80 SSINPGIGNVSAS-SPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAA 138 Query: 789 RPPGPSPHMAQQHGDPATT----ANNDVSLSQMMPDV----SIQQTNMVPPHVQAMQGNS 840 GP+P +Q A A + + SQ P + + QT+ P + + G+S Sbjct: 139 STSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTH--PGLLNSNSGHS 196 Query: 841 ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQ--SDISAG 898 G N A G G +P +S +L L S G Sbjct: 197 LINQASQGQAQVMNGSLGAAGRGR----GAGMPYPTPAMQGASSSVLAETLTQVSPQMTG 252 Query: 899 HFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAG--LEEADQPPLPGEQGINL 956 H G+N Q A T +T P G +A P+ G G+N Sbjct: 253 HAGLNTAQAGGMAKMGI----------------TGNTSPFGQPFSQAGGQPM-GATGVN- 294 Query: 957 DNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQ-- 1014 P+L + P+ P + + V P Q Q + Q Sbjct: 295 ----PQLASKQSMVNSLPTFPTDIKNTS---------VTNVPNMSQMQTSVGIVPTQAIA 341 Query: 1015 PPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSG 1074 P + P+ ++ QQQ +++ Q + V P + M Q+G Sbjct: 342 TGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG 401 Query: 1075 SVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMA-SLP 1133 + L PAS Q V T G + + +P +PSS A A LP Sbjct: 402 KACQAI-LGSPAS-----GIQNTIGSVGT--GQQNATSLSNPNPIDPSSMQRAYAALGLP 453 Query: 1134 EASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKP-GPSPLSATQGA--TPQQPP----V 1186 + + P P P+ PQ M P G +P++ G T QQPP Sbjct: 454 YMNQPQTQLQPQVPGQQPAQ---PQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISE 510 Query: 1187 NSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNA 1246 ++LP+S G P + + + T + P P + R E L ++ Sbjct: 511 SALPTSLGATNPLMNDGSNSGNIGTLSTI-PTAAPPSSTGVRKGWHEHVTQDLRSHLVHK 569 Query: 1247 SIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLD 1306 + +FP L R N L A + +N H L Sbjct: 570 LVQAIFPTPDPAALKDRRMEN------------LVAYAKKVEGDMYESANSRDEYYHLLA 617 Query: 1307 SVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQ 1366 + K+ R + P P+PG Q P+ N L Sbjct: 618 EKIYKIQKELEEKRRSRLHKQGILGNQPA-----LPAPGAQPPVIPQAQPVRPPNGPL-- 670 Query: 1367 NVELPRNVL--------VSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKES 1418 LP N + +P L N +P + +P N +V + ++G V Sbjct: 671 --SLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISP 728 Query: 1419 LNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKD--------GQPS----- 1465 +PQ + + + N + PAQ +P++Q GQP Sbjct: 729 SRMPQPPNMMGAHT-----NNMMAQAPAQS--QFLPQNQFPSSSGAMSVGMGQPPAQTGV 781 Query: 1466 DPNKLP--SVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGE 1523 ++P ++ N++ P + P P G+ L+ T P Sbjct: 782 SQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTP 841 Query: 1524 DLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPV 1583 A P+ SS + P+ P + S+ V + + P PV Sbjct: 842 PQPAAPTQPSTPVSSSGQTPT-----PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPV 896 Query: 1584 SSSSISTPLPPNQITVFVTSNPITTSANTSAA-----LPTHLQSALMSTVVTMPNAGSKV 1638 S++TP Q V + P T + +AA +PT S++ S G V Sbjct: 897 QPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPT--PSSVASAETNSQQPGPDV 954 Query: 1639 MVSEGQSAAQS 1649 V E ++ Q+ Sbjct: 955 PVLEMKTETQA 965 Score = 37.4 bits (85), Expect = 0.15 Identities = 45/168 (26%), Positives = 59/168 (35%), Gaps = 23/168 (13%) Query: 1644 QSAAQSNARPQFITPVFINSSSIIQ----VMKGSQPSTIPAAPLTTNSGLMPPSVAVVGP 1699 Q AQ P ++P S + Q V G S +PA P PP AV Sbjct: 1866 QPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQ----PPPAAVEAA 1921 Query: 1700 LHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQL--PSPPCTSSPVVPSH 1757 I + + N +S P G P S+ PV L P P S PV+PS Sbjct: 1922 RQIEREAQQQQHLYRVNINNSMPPGRTGMGTP---GSQMAPVSLNVPRPNQVSGPVMPSM 1978 Query: 1758 PPVQQVKELNPDE----------ASPQVNTSADQNTLPSSQSTTMVSP 1795 PP Q + P + S Q + +PS Q +SP Sbjct: 1979 PPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISP 2026 >gi|119943104 CREB binding protein isoform a [Homo sapiens] Length = 2442 Score = 82.4 bits (202), Expect = 4e-15 Identities = 155/575 (26%), Positives = 213/575 (37%), Gaps = 82/575 (14%) Query: 270 QQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTA-----PTQVPVPPGWNQLPSG 324 +QQQ Q + QQ Q ++ R + + PQ P T+ PTQ P P Q P Sbjct: 1851 RQQQIQ--HRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTP---QTPQP 1905 Query: 325 ALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPP--PYPFGSQQ 382 QP P+ S+ + G+ P +P T Q P+ PPP P P + Sbjct: 1906 PAQPQPSPVSM----SPAGFPSVARTQPPTTVSTGKP---TSQVPAPPPPAQPPPAAVEA 1958 Query: 383 ASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPAS--SPSSFQQGSP 440 A Q Q + + S+ G + + TP Q +P S P Q P Sbjct: 1959 ARQIEREAQQQQH--LYRVNINNSMPPGRTGMGTPGSQ-----MAPVSLNVPRPNQVSGP 2011 Query: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQG 500 P++ Q Q P PQ P+P G +PV S M Q V M Q P + Sbjct: 2012 V-MPSMPPGQWQQAPL-PQQQPMP-GLPRPVIS-----MQAQAAVAGPRMPSVQPPRSIS 2063 Query: 501 PQSLHPGLGGM-----PKRLPPGFSAGQANPNFMQGQVPSTT----ATTPGNSGAPQLQA 551 P +L L + P++ + ++NP M + T A PG P LQ+ Sbjct: 2064 PSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQS 2123 Query: 552 NQNVQHAGGQGAGPP-QNQMQVSHGPPNMMQPSLMGIHGNMNNQ-QAGTSGVP--QVNLS 607 +Q G P QN + G P P G +N Q QA P N++ Sbjct: 2124 QPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMA 2183 Query: 608 NMQGQPQQGPPSQLM-GMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPP 666 +M Q ++ QL+ QQ Q Q QQQG+ M PQG P Sbjct: 2184 SMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPA 2243 Query: 667 SQNLGPSPQRMTPPKQMLSQQGPQM--MAPHNQMMGPQGQVLL--QQNPMIEQIMTN--- 719 Q QRM +Q L QG M MA +G GQ L P I+Q + Sbjct: 2244 MQ----QQQRM---QQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRIL 2296 Query: 720 QMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQM---------LPQQ 770 Q Q KQQ + Q N M ++ G Q +S Q+ PQ Sbjct: 2297 QQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQS 2356 Query: 771 GPVNNSPSQVMGIQGQVLRPPGPSP-HMAQQHGDP 804 P ++SPS + P PSP H++ Q G P Sbjct: 2357 QPPHSSPSPRI--------QPQPSPHHVSPQTGSP 2383 Score = 79.3 bits (194), Expect = 4e-14 Identities = 99/345 (28%), Positives = 130/345 (37%), Gaps = 48/345 (13%) Query: 183 MIPPGGNVSSSMMAPGPNPELQPRTPR-PASQSDAMDPLLSGLHIQQQS----HPSGS-- 235 M P G S M P P QP A Q+ P G+ QQQ+ +P G Sbjct: 2115 MQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRP---GVPPQQQAMGGLNPQGQAL 2171 Query: 236 --LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQ--LQARPP 291 + P H+P MNP L++Q QQQQQQQQQQQQQQQQQQ + Sbjct: 2172 NIMNPGHNPNMA-----SMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMA 2226 Query: 292 QQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPG 351 Q QQPQG PP Q P S+G M A G Sbjct: 2227 GHGQFQQPQG---------PGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMG-------- 2269 Query: 352 PMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFT--APQMKSLQG 409 Q +P L TP+ Q+ Q Q+ +PGQ +PQ L G Sbjct: 2270 --QLGQMGQPGLGADSTPNIQQAL----QQRILQQQQMKQQIGSPGQPNPMSPQQHMLSG 2323 Query: 410 GPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQ-GFQ 468 P P QQ + + SP+ Q P S P + ++ P+P ++ PQ G Sbjct: 2324 QPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSP 2383 Query: 469 QPVSSPGRNPMVQQ---GNVPPNFMVMQQQPPNQGPQSLHPGLGG 510 P + + Q GN + M+ Q P++ S L G Sbjct: 2384 HPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVG 2428 Score = 78.6 bits (192), Expect = 6e-14 Identities = 139/552 (25%), Positives = 184/552 (33%), Gaps = 119/552 (21%) Query: 225 HIQQQSHPSGSLAPPHHPMQPVSVNR-------------QMNPANFPQLQQQQ------- 264 ++ QQS PS + APP P Q S + M+PA FP + + Q Sbjct: 1876 NVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVST 1935 Query: 265 ---------------------QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIR 303 + +Q +++ QQQQ + + PP + G Sbjct: 1936 GKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPP----GRTGMGTP 1991 Query: 304 PQFTAPTQVPVPPGWNQLPSGALQP--PPAQGSLGTMTANQGWKKAPLPGPMQQQLQARP 361 AP + VP NQ+ SG + P PP Q W++APLP Q Q P Sbjct: 1992 GSQMAPVSLNVPRP-NQV-SGPVMPSMPPGQ-----------WQQAPLP-----QQQPMP 2033 Query: 362 SLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQP 421 L P P S QA A P+M S+Q S P+ LQ Sbjct: 2034 GL-----------PRPVISMQAQAA------------VAGPRMPSVQPPRSISPSALQDL 2070 Query: 422 HLTNKSPASSPSSFQQ-------GSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSP 474 T KSP SSP QQ + + Q + P P P QP P Sbjct: 2071 LRTLKSP-SSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQP 2129 Query: 475 GRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKR------LPPGFSAGQA--NP 526 P + Q N MQ P G +GG+ + + PG + A NP Sbjct: 2130 --QPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNP 2187 Query: 527 NFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHG----PPNMMQP 582 + + Q Q Q AG G Q Q G PP M Q Sbjct: 2188 QYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQ 2247 Query: 583 SLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPS--QLMGMHQQIVPSQGQMVQQQG 640 M H + G L M GQP G S + QQ + Q QM QQ G Sbjct: 2248 QRMQQHLPLQGSSMGQMAAQMGQLGQM-GQPGLGADSTPNIQQALQQRILQQQQMKQQIG 2306 Query: 641 TLNPQNPMILSRAQLMPQGQMMVNP-PSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMM 699 + NPM S Q M GQ + P Q + S + PQ PH+ Sbjct: 2307 SPGQPNPM--SPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHS--- 2361 Query: 700 GPQGQVLLQQNP 711 P ++ Q +P Sbjct: 2362 SPSPRIQPQPSP 2373 Score = 72.8 bits (177), Expect = 3e-12 Identities = 225/1026 (21%), Positives = 340/1026 (33%), Gaps = 208/1026 (20%) Query: 361 PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPT-PLQ 419 P + V S P G Q Q P +N +A L G S P+ P Q Sbjct: 84 PGIGNVSASS--PVQQGLGGQAQGQ-----PNSANMASLSAMGKSPLSQGDSSAPSLPKQ 136 Query: 420 QPHLTNKSPASSPS-----SFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSP 474 + +PA+S + Q G SSP +QT GP N Q ++S Sbjct: 137 AASTSGPTPAASQALNPQAQKQVGLATSSPATSQT----GPGICMNANFNQTHPGLLNSN 192 Query: 475 GRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPN-FMQGQV 533 + ++ Q + QG + G G R G AG P MQG Sbjct: 193 SGHSLINQAS--------------QGQAQVMNGSLGAAGR---GRGAGMPYPTPAMQGAS 235 Query: 534 PSTTATTPGNSGAPQL--QANQNVQHAGGQGA----------GPPQNQMQVSHGPPNMMQ 581 S A T +PQ+ A N AGG G P +Q + Sbjct: 236 SSVLAETL-TQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVN 294 Query: 582 PSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGP-----PSQLMGMHQQIVPSQGQMV 636 P L +N+ + + +++N+ Q P+Q + P + +++ Sbjct: 295 PQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLI 354 Query: 637 QQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPH- 695 QQQ L R Q + + P + + MT Q G H Sbjct: 355 QQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTH-----CQAGKACQVAHC 409 Query: 696 ---NQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQ 752 Q++ P+ + K + +NQ ++ PA ++ ++ Sbjct: 410 ASSRQIISHWKNCTRHDCPVCLPL--------KNASDKRNQQTILGSPASGIQNTIGSVG 461 Query: 753 GNMVQFTGQMSGQMLPQQGPVNNSPSQ----VMGIQGQVLRPPGPSPHMAQQHGDPATTA 808 TGQ + L P++ S Q +G+ P+M Q Sbjct: 462 ------TGQQNATSLSNPNPIDPSSMQRAYAALGL-----------PYMNQPQ------- 497 Query: 809 NNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSC 868 +Q+ P V QQ H Q N N N P G ++ Sbjct: 498 ------TQLQPQVPGQQPAQPQTHQQMRTLNPLGNN-------PMNIPAGG------ITT 538 Query: 869 GQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKK-KNSQ 927 Q P +++ TS N L +D G N+ T + P P + Sbjct: 539 DQQPPNLISESALPTSLGATNPLMND------GSNSGNIGTLSTIPTAAPPSSTGVRKGW 592 Query: 928 QDLNTPDTRPAGLEEADQPPLPGEQGINL-DNSGPKLPEFSNRPPG--YPS--------- 975 + T D R + + Q P L D L ++ + G Y S Sbjct: 593 HEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYH 652 Query: 976 ----------QPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQ 1025 + +E++ ++ Q + P P QP P +PQ Q PP+ P S Sbjct: 653 LLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQP-PVIPQAQPVRPPNGPLSLP 711 Query: 1026 QQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGP--LNPDSQRMPMQQSGSVPVMVSLQ 1083 + Q M +V+LP P GP +P + + M GSVP M Sbjct: 712 VNRMQVSQGMNSFNPMSLGNVQLP-----QAPMGPRAASPMNHSVQMNSMGSVPGM---- 762 Query: 1084 GPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQES------PQN--PSSSPLAE--MASLP 1133 ++ PS RMP P N +G+++ M+ Q PQN PSSS M P Sbjct: 763 ---AISPS----RMPQPPNM-MGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPP 814 Query: 1134 EASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGP------KPGPSPLSATQGATPQQ---P 1184 +G VPG P +++ PQ + P P P P S G Q P Sbjct: 815 AQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTP 874 Query: 1185 PVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERL 1244 P G P AAPTQ S P + + +P P TP + P +T+ + S + Sbjct: 875 P--------GMTPPQPAAPTQPSTPVSSSGQTPTP----TPGSVPSATQ----TQSTPTV 918 Query: 1245 NASIAGLFPPQINIPLPPRPNLNRGFDQQGLNP-------TTLKAIGQAPSNLTMNPSNF 1297 A+ PQ P+ P QQ P T L + N PS+ Sbjct: 919 QAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSV 978 Query: 1298 ATPQTH 1303 A+ +T+ Sbjct: 979 ASAETN 984 Score = 72.8 bits (177), Expect = 3e-12 Identities = 154/601 (25%), Positives = 212/601 (35%), Gaps = 93/601 (15%) Query: 381 QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQ----QPHLTNKSPASSPSSFQ 436 + A+ N PQ S P +AP Q PS TP QP + SPA PS + Sbjct: 1868 RMATMNTRNVPQQSLPSPTSAPPGTPTQQ-PSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1926 Query: 437 QGSPASSPTVNQTQQQMGPRPPQ----------------------------NNPLPQGFQ 468 P + T T Q P PP NN +P G + Sbjct: 1927 TQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPG-R 1985 Query: 469 QPVSSPGRNPMVQQGNVP-PNFM---VMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQA 524 + +PG NVP PN + VM PP Q Q+ P MP LP + QA Sbjct: 1986 TGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMP-GLPRPVISMQA 2044 Query: 525 NPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQ--MQVSHGPPNMMQP 582 ++PS P S +P A Q++ + P Q Q + + P +M Sbjct: 2045 QAAVAGPRMPS---VQPPRSISP--SALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAA 2099 Query: 583 SLMGIHGNMNNQQAGTSGVPQVNLSNMQG-QPQQG----PPSQLMGMHQQIVPSQGQMVQ 637 + Q G PQ L + G QPQ G P Q + Q VP G Q Sbjct: 2100 FIKQRTAKYVANQPGMQ--PQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQ 2157 Query: 638 QQ--GTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPH 695 QQ G LNPQ + +M G NP ++ P + M +Q+L QQ Q Sbjct: 2158 QQAMGGLNPQGQAL----NIMNPGH---NPNMASMNPQYREML-RRQLLQQQQQQQQQQQ 2209 Query: 696 NQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPG--PAQIMRGPTPNMQG 753 Q QG M M G+ Q Q P Q M+ P Sbjct: 2210 QQQQQQQGSA----------GMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGS 2259 Query: 754 NMVQFTGQMS--GQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANND 811 +M Q QM GQM +++P+ +Q ++L+ M QQ G P N Sbjct: 2260 SMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQ----QQQMKQQIGSPGQP--NP 2313 Query: 812 VSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQN 871 +S Q M Q +++ + S S S + P S P+ + Q Sbjct: 2314 MSPQQHMLSGQPQASHLPGQQI----ATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQP 2369 Query: 872 PGFP--VNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQD 929 P V+ P L + S I GH G N +Q +A P+ P R +S+ Sbjct: 2370 QPSPHHVSPQTGSPHPGLAVTMASSIDQGHLG-NPEQ---SAMLPQLNTPSRSALSSELS 2425 Query: 930 L 930 L Sbjct: 2426 L 2426 Score = 62.8 bits (151), Expect = 3e-09 Identities = 126/475 (26%), Positives = 165/475 (34%), Gaps = 79/475 (16%) Query: 128 QIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMA----SGPGIIRMNNPATVM 183 QIE E A Q V +N M G + G MA + P +++ P Sbjct: 1961 QIERE-----AQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPS 2015 Query: 184 IPPGGNVSSSMMAPGPNPELQPRTPRPA----SQSDAMDPLLSGLHIQQQSHPSG----- 234 +PPG AP P + P PRP +Q+ P + + + PS Sbjct: 2016 MPPG----QWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLL 2071 Query: 235 -SLAPPHHPMQPVSVNR--QMNP---------------ANFPQLQQQQQQQQQQQQQQQ- 275 +L P P Q V + NP AN P +Q Q Q Q Q Q Sbjct: 2072 RTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQP 2131 Query: 276 ---QQQQQQQQQQLQA---RPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPP 329 QQ Q +QA RP QQQ G+ PQ A + PG N P+ A P Sbjct: 2132 GMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALN--IMNPGHN--PNMASMNP 2187 Query: 330 PAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLA-------TVQTPSHPPPPYPFGSQQ 382 + L Q ++ QQQ Q +A Q P P YP QQ Sbjct: 2188 QYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQP-QGPGGYPPAMQQ 2246 Query: 383 ASQAHTNFP-QMSNPGQFTAPQMKSL----QGGPSRVPTPLQQPHLTNKSPASSPSSFQQ 437 + + P Q S+ GQ A QM L Q G TP Q L + Q Sbjct: 2247 QQRMQQHLPLQGSSMGQMAA-QMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQI 2305 Query: 438 GSPASSPTVNQTQQQMGPRPPQNNPLP-QGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQP 496 GSP P QQ M PQ + LP Q +S+ R+P Q P Q QP Sbjct: 2306 GSP-GQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRP------QSQP 2358 Query: 497 PNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQA 551 P+ P P + P G +P V ++ G+ G P+ A Sbjct: 2359 PHSSPS---PRIQPQPSPHHVSPQTGSPHPGL---AVTMASSIDQGHLGNPEQSA 2407 Score = 60.8 bits (146), Expect = 1e-08 Identities = 141/596 (23%), Positives = 203/596 (34%), Gaps = 97/596 (16%) Query: 720 QMQGNKQQFNTQNQSNV----MPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNN 775 Q Q +++ T N NV +P P G TP Q + Q T Q Q PQ PV+ Sbjct: 1861 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPG-TPTQQPSTPQ-TPQPPAQ--PQPSPVSM 1916 Query: 776 SPS---QVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPH 832 SP+ V Q G PA V ++ + + QQ ++ + Sbjct: 1917 SPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVN 1976 Query: 833 VQAMQGNSASGNHFSGHGMSFNAPFS-GAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLL 891 + +G G M AP S P NQ+S P P + +PL Sbjct: 1977 INNSMPPGRTGMGTPGSQM---APVSLNVPRPNQVSGPVMPSMPPGQ--WQQAPLPQQQP 2031 Query: 892 QSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGE 951 + + + P + P ++ QDL P+ P + Sbjct: 2032 MPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSS-------PQQQQ 2084 Query: 952 QGINLDNSGPKLPE----------FSNRP-----PGYPSQP-------VEQRPLQQMPPQ 989 Q +N+ S P+L +N+P PG SQP + Q+P Q Sbjct: 2085 QVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNA 2144 Query: 990 LMQHVAPPPQPPQQQ------PQ-------------------PQLPQQQQPPPPSQPQSQ 1024 + V P PPQQQ PQ PQ + + Q Q Q Sbjct: 2145 MQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQ 2204 Query: 1025 QQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPP-RGPLNPDSQRMPMQQSGSVPVMVSLQ 1083 QQQQQQQQ QQ S + H + P P MQQ + + LQ Sbjct: 2205 QQQQQQQQ-------QQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQ 2257 Query: 1084 GPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSV 1143 G + + ++ LG++S + Q Q + + + + GS Sbjct: 2258 GSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQR-----ILQQQQMKQQIGS----- 2307 Query: 1144 PGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAP 1203 PG PN M PQ Q M++G +P S L Q AT V S P+ P P Sbjct: 2308 PGQPNPMS-----PQ-QHMLSG-QPQASHLPGQQIATSLSNQVRS-PAPVQSPRPQSQPP 2359 Query: 1204 TQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIP 1259 + P+ + SP PQT + P S+ L PQ+N P Sbjct: 2360 HSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTP 2415 Score = 49.3 bits (116), Expect = 4e-05 Identities = 144/657 (21%), Positives = 210/657 (31%), Gaps = 145/657 (22%) Query: 559 GGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPP 618 G G G QN +S+ PN + PS M + G+P +N Q QPQ P Sbjct: 458 GSVGTGQ-QNATSLSN--PNPIDPSSM-------QRAYAALGLPYMNQPQTQLQPQV--P 505 Query: 619 SQLMGMHQQIVPSQGQMVQQQGTLNP--QNPMILSRAQLMPQGQMMVNPPSQNLGPSPQR 676 Q P+Q Q QQ TLNP NPM N P+ + Q Sbjct: 506 GQQ--------PAQPQTHQQMRTLNPLGNNPM---------------NIPAGGITTDQQ- 541 Query: 677 MTPPKQMLSQQGPQMMAPHNQMMGP---QGQV-LLQQNPMIEQIMTNQMQGNKQQFNTQN 732 PP + P + N +M G + L P + ++ + TQ+ Sbjct: 542 --PPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQD 599 Query: 733 QSNVMPGPAQIMRGPTPNMQG-------NMVQFTGQMSGQM------------------- 766 + + PTP+ N+V + ++ G M Sbjct: 600 LRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIY 659 Query: 767 -------------LPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVS 813 L +QG + N P+ L PG P + Q P N +S Sbjct: 660 KIQKELEEKRRSRLHKQGILGNQPA---------LPAPGAQPPVIPQ-AQPVRPPNGPLS 709 Query: 814 LSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPG 873 L VS + P + +Q A G +P + + N M G PG Sbjct: 710 LPVNRMQVSQGMNSFNPMSLGNVQLPQAP------MGPRAASPMNHSVQMNSM--GSVPG 761 Query: 874 FPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKK--PPRKKKNSQQDLN 931 ++ P ++ NN A P + + P + +S ++ Sbjct: 762 MAISPSRMPQPPNMMGA--------------HTNNMMAQAPAQSQFLPQNQFPSSSGAMS 807 Query: 932 TPDTRPAGLEEADQPPLPGEQGIN-LDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQL 990 +P Q +PG N L+ GP+ + P PV Q PL PP Sbjct: 808 VGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQL-------PCPPVTQSPLHPTPPPA 860 Query: 991 --------MQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQD 1042 +QH PP P PQP P QP P Q + Q Sbjct: 861 STAAGMPSLQHTTPPGMTP---PQPAAP--TQPSTPVSSSGQTPTPTPGSVPSATQTQST 915 Query: 1043 PKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVN 1102 P +Q P+ P+ P S P Q S P V Q P P S + V Sbjct: 916 PTVQAAAQAQVTPQPQTPVQPPSVATP-QSSQQQPTPVHAQ-PPGTPLSQAAASIDNRVP 973 Query: 1103 TPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQN 1159 TP +S S Q P+ EM + +A +E PG P ++ ++ Sbjct: 974 TP---SSVASAETNSQQPGPDVPVLEMKTETQAEDTEPD--PGESKGEPRSEMMEED 1025 Score = 48.9 bits (115), Expect = 5e-05 Identities = 85/345 (24%), Positives = 118/345 (34%), Gaps = 67/345 (19%) Query: 982 PLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQ 1041 P Q +P APP P QQ PQ PQ PP+QPQ + Q Sbjct: 1878 PQQSLPSPTS---APPGTPTQQPSTPQTPQ-----PPAQPQPSPVSMSPAGFPSVARTQP 1929 Query: 1042 DPK-SVRLPVSQNVHPPRGPLNPDS--------QRMPMQQSGSVPVMVSLQGPASVPP-- 1090 S P SQ PP P + +R QQ V ++ S+PP Sbjct: 1930 PTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNIN----NSMPPGR 1985 Query: 1091 ----SPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGG 1146 +P Q P+ +N P N S P+ M S+P +AP Sbjct: 1986 TGMGTPGSQMAPVSLNVP-------------RPNQVSGPV--MPSMPPGQWQQAPLPQQQ 2030 Query: 1147 P-NNMPSHVVLPQNQLMMTGPK-PGPSP---------------LSATQGATPQQPPVNSL 1189 P +P V+ Q Q + GP+ P P L + QQ +N L Sbjct: 2031 PMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNIL 2090 Query: 1190 PSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIA 1249 S+ + T P P+P P +P + SL + LNA A Sbjct: 2091 KSNPQLMAAFIKQRTAKYVANQPG-MQPQPGLQSQPGMQPQPGMHQQPSL--QNLNAMQA 2147 Query: 1250 GLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNP 1294 G+ P + PP+ G + QG + G P+ +MNP Sbjct: 2148 GVPRPGV----PPQQQAMGGLNPQG-QALNIMNPGHNPNMASMNP 2187 Score = 48.5 bits (114), Expect = 7e-05 Identities = 93/431 (21%), Positives = 147/431 (34%), Gaps = 82/431 (19%) Query: 1126 LAEMASLPEASGSEAPSVPGGPNNMPSH--VVLPQNQLMMTGPKPGPSPLSATQGATPQQ 1183 L +LP A G++ P +P P + + LP N++ ++ +P+S PQ Sbjct: 679 LGNQPALP-APGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQA 737 Query: 1184 P--PVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPN------NRPPSTEPS 1235 P P + P +H + S P A PQ PN N + P+ Sbjct: 738 PMGPRAASPMNH--------SVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPA 789 Query: 1236 EISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPS 1295 + P+ S +G + + PP Q G++ GQ P NP Sbjct: 790 QSQFLPQNQFPSSSGAM--SVGMGQPPA--------QTGVSQ------GQVPGAALPNPL 833 Query: 1296 NFATPQTHKLDSVVVNSGKQSNS---GATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAP 1352 N PQ +L V + +T PS + PG T P P + Sbjct: 834 NMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPG---MTPPQPAAPTQPST 890 Query: 1353 KLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVV 1412 ++ + QT PT P PGS P ++ TV AA V Sbjct: 891 PVSSSGQT-----------------PT-----PTPGSVP-SATQTQSTPTVQAAAQAQVT 927 Query: 1413 EDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPS 1472 + + P + Q+SQ + V+ + P + + D + P+ + S Sbjct: 928 PQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASI-------DNRVPTPSSVAS 980 Query: 1473 VEENKNLVSP--AMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASV 1530 E N P + E T +Q D P + P +E EDL+ AS Sbjct: 981 AETNSQQPGPDVPVLEMKTE-TQAEDTEPDPGESKGEPRSEMME--------EDLQGASQ 1031 Query: 1531 IPTLQDLSSSK 1541 + D++ K Sbjct: 1032 VKEETDIAEQK 1042 Score = 43.5 bits (101), Expect = 0.002 Identities = 84/390 (21%), Positives = 120/390 (30%), Gaps = 73/390 (18%) Query: 204 QPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQ 263 QP P P +Q + Q P+G L+ P + MQ NP + +Q Sbjct: 682 QPALPAPGAQPPVIP------QAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP 735 Query: 264 QQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPS 323 Q + A P H Q + PG PS Sbjct: 736 QAPMGPR-----------------AASPMNHSVQM-----------NSMGSVPGMAISPS 767 Query: 324 GALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQA 383 QPP G+ N +AP Q Q PS + + PP G Q Sbjct: 768 RMPQPPNMMGA----HTNNMMAQAPAQSQFLPQNQF-PSSSGAMSVGMGQPPAQTGVSQG 822 Query: 384 SQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASS 443 P NP PQ L P Q P PAS+ + + Sbjct: 823 QVPGAALP---NPLNMLGPQASQLP-----CPPVTQSPLHPTPPPASTAAGMPSLQHTTP 874 Query: 444 PTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQS 503 P + Q +P + P+ Q P +PG P Q P Q PQ+ Sbjct: 875 PGMTPPQPAAPTQP--STPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQT 932 Query: 504 -LHPGLGGMPK----------RLPPGFSAGQANPNF-MQGQVPSTTATTPGNSGAP---- 547 + P P+ PPG QA + + PS+ A+ NS P Sbjct: 933 PVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDV 992 Query: 548 -------QLQANQNVQHAGGQGAGPPQNQM 570 + QA ++ + G+ G P+++M Sbjct: 993 PVLEMKTETQA-EDTEPDPGESKGEPRSEM 1021 Score = 42.0 bits (97), Expect = 0.006 Identities = 74/332 (22%), Positives = 123/332 (37%), Gaps = 44/332 (13%) Query: 1576 PPVM--SRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPN 1633 PPV+ ++PV + LP N++ V N + + LP A M P Sbjct: 692 PPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP----QAPMGPRAASPM 747 Query: 1634 AGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGS--QPSTIPAAPLTTNSGLMP 1691 S M S G + + + P + + +M + Q +P ++SG M Sbjct: 748 NHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMS 807 Query: 1692 PSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPL-VLSSRATPVQLPSPPCTS 1750 VG P S VP AL PN PL +L +A+ QLP PP T Sbjct: 808 -----VGMGQPPAQTGVSQGQVPGAAL-----PN-----PLNMLGPQAS--QLPCPPVTQ 850 Query: 1751 SPVVPSHPP------VQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSS 1804 SP+ P+ PP + ++ P +P + Q + P S S +P + P ++ Sbjct: 851 SPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSAT 910 Query: 1805 GNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGL 1864 + +P + + +V Q T + + ++Q + PG Sbjct: 911 QTQSTPTVQAAAQAQVTPQPQ---TPVQPPSVATPQSSQQQ--------PTPVHAQPPG- 958 Query: 1865 MGTEQLSTELDSKTPTPPAPTLLKMTSSPVGP 1896 Q + +D++ PTP + + S GP Sbjct: 959 TPLSQAAASIDNRVPTPSSVASAETNSQQPGP 990 Score = 37.4 bits (85), Expect = 0.15 Identities = 45/168 (26%), Positives = 59/168 (35%), Gaps = 23/168 (13%) Query: 1644 QSAAQSNARPQFITPVFINSSSIIQ----VMKGSQPSTIPAAPLTTNSGLMPPSVAVVGP 1699 Q AQ P ++P S + Q V G S +PA P PP AV Sbjct: 1904 QPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQ----PPPAAVEAA 1959 Query: 1700 LHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQL--PSPPCTSSPVVPSH 1757 I + + N +S P G P S+ PV L P P S PV+PS Sbjct: 1960 RQIEREAQQQQHLYRVNINNSMPPGRTGMGTP---GSQMAPVSLNVPRPNQVSGPVMPSM 2016 Query: 1758 PPVQQVKELNPDE----------ASPQVNTSADQNTLPSSQSTTMVSP 1795 PP Q + P + S Q + +PS Q +SP Sbjct: 2017 PPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISP 2064 Score = 36.6 bits (83), Expect = 0.26 Identities = 116/580 (20%), Positives = 189/580 (32%), Gaps = 75/580 (12%) Query: 1106 GSNSRKMVYQESPQNPSSSPLAEMA-SLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMT 1164 G + + +P +PSS A A LP + + P P P+ PQ M Sbjct: 463 GQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQ---PQTHQQMR 519 Query: 1165 GPKP-GPSPLSATQGA--TPQQPP----VNSLPSSHGHHFPNVAAPTQTSRPKTPNRASP 1217 P G +P++ G T QQPP ++LP+S G P + + + T + P Sbjct: 520 TLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTI-P 578 Query: 1218 RPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNP 1277 P + R E L ++ + +FP L R N Sbjct: 579 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMEN---------- 628 Query: 1278 TTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSS 1337 L A + +N H L + K+ R + P Sbjct: 629 --LVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPA-- 684 Query: 1338 RKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVL--------VSPTPLANPPVPGS 1389 P+PG Q P+ N L LP N + +P L N +P + Sbjct: 685 ---LPAPGAQPPVIPQAQPVRPPNGPL----SLPVNRMQVSQGMNSFNPMSLGNVQLPQA 737 Query: 1390 FPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEV 1449 +P N +V + ++G V +PQ + + + N + PAQ Sbjct: 738 PMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT-----NNMMAQAPAQS- 791 Query: 1450 KMVVPEDQSKKD--------GQPS-----DPNKLP--SVEENKNLVSPAMREAPTSLSQL 1494 +P++Q GQP ++P ++ N++ P + P Sbjct: 792 -QFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQ 850 Query: 1495 LDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNE 1554 P G+ L+ T P A P+ SS + P+ P Sbjct: 851 SPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT-----PTPGS 905 Query: 1555 LCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSA 1614 + S+ V + + P PV S++TP Q V + P T + +A Sbjct: 906 VPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAA 965 Query: 1615 A-----LPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQS 1649 A +PT S++ S G V V E ++ Q+ Sbjct: 966 ASIDNRVPT--PSSVASAETNSQQPGPDVPVLEMKTETQA 1003 >gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] Length = 1426 Score = 82.4 bits (202), Expect = 4e-15 Identities = 291/1303 (22%), Positives = 429/1303 (32%), Gaps = 236/1303 (18%) Query: 199 PNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPAN-- 256 P P + P+PA+ +D G ++ + PS P+ P P N Sbjct: 256 PTPPIPAPAPKPAAPPRPLDRESPG--VENKLIPSVGSPASSTPLPPDGTGPNSTPNNRA 313 Query: 257 -FPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRP-QFTAPTQVPV 314 P Q + + L P Q+Q R Q Q + Sbjct: 314 VTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRML 373 Query: 315 PPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPP 374 P + +GA P Q G + G +K P GP+Q + SL P P Sbjct: 374 FPDEKEF-TGAQSGGPQQNP-GVL---DGPQKKP-EGPIQAMMAQSQSLG-----KGPGP 422 Query: 375 PYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQG--GPSRVP--TP-------LQQPHL 423 G+ Q H + P +P + P M S G GP + TP LQQ Sbjct: 423 RTDVGAPFGPQGHRDVP--FSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFY 480 Query: 424 TNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVS--SPGRNPMVQ 481 K QQ S + Q GPR P P P +PG Sbjct: 481 EEKRRKQEQVVVQQCS-----LQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFS 535 Query: 482 QGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTP 541 G P+ + + P HP + G RLP GF AG N VP+ A+ P Sbjct: 536 DGINMPHSLPPRGMAP-------HPNMPGSQMRLP-GF-AGMINSEMEGPNVPNP-ASRP 585 Query: 542 GNSGA------PQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQ 595 G SG P++ +N G +GP + + P+ G+ M QQ Sbjct: 586 GLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERF----------PNPQGLSEEMFQQQ 635 Query: 596 AGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQL 655 Q+ L PP M + I PS N MI + Sbjct: 636 LAEK---QLGL----------PPGMAM---EGIRPSM-----------EMNRMIPGSQRH 668 Query: 656 MPQGQMMVNPPSQNLGP-SPQRMTPPKQMLSQQGPQMMAPHNQM-MGPQGQVLLQQN--- 710 M G + P GP SP R PK + Q GP + G +G V L N Sbjct: 669 MEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGS 728 Query: 711 --PMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLP 768 MI Q M G ++ + + M PAQ P P + ++ G LP Sbjct: 729 NSQMIPQKMREAGAGPEEMLKLRPGGSDML-PAQQKMVPLPFGEHPQQEY-GMGPRPFLP 786 Query: 769 Q-QGPVNNSPSQVMGIQGQVLRPPGP----SPHMAQQHGDPATTANNDVSLSQMMP---- 819 QGP +NS G++ + P GP + ++ P ++N SL+ P Sbjct: 787 MSQGPGSNS-----GLRN-LREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRG 840 Query: 820 ------DVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPG 873 D+S+ + + P + ++ + +P G+P+GN S P Sbjct: 841 LGRKPLDISVAGSQVHSPGINPLKSPTMH---------QVQSPMLGSPSGNLKS----PQ 887 Query: 874 FPVNKDVTLTSPLLVNLLQSDI---SAGHFGVNNKQNNTNANKP---KKKKPPRKKKNSQ 927 P L P ++S SA V+ K + A P KPP + Sbjct: 888 TPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIP 947 Query: 928 QDLNTPDTRPA-----GLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQP-VEQR 981 + P T + +E PP Q +++ G LP S+ P P +P + Q Sbjct: 948 PNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPG-SLP--SSTPYTMPPEPTLSQN 1004 Query: 982 PLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMM------ 1035 PL M ++ + P P + PP++ + M + Sbjct: 1005 PLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPR 1064 Query: 1036 ---------------MLMMQQDPKSVRLP----VSQNVHPPRGPLNPD-SQRMPMQQSGS 1075 M M Q S ++P V N+ P P+ P P+ GS Sbjct: 1065 ISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGS 1124 Query: 1076 VPVMVSLQG----PASVPP--SPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEM 1129 + QG P PP SP +Q +P P N P G + P PL Sbjct: 1125 QEPPMVPQGRMGFPQGFPPVQSPPQQ-VPFPHNGPSGGQGS---FPGGMGFPGEGPLGRP 1180 Query: 1130 ASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSL 1189 ++LP++S A PGGP S VL + PS + +P + Sbjct: 1181 SNLPQSSADAALCKPGGPGGPDSFTVLGNSM---------PSVFTDPDLQEVIRPGATGI 1231 Query: 1190 PSSHGHHFPNVAAPTQT----SRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLN 1245 P P+QT R + P R P+ P + + E + R+ Sbjct: 1232 PEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQA------PRMG 1285 Query: 1246 ASIAGLFPP----QINIPLPPRPNLNRGFDQQGLNPTTLKAIGQ----APSNLTMNPSNF 1297 ++ G+ P +IPL P++ G NP A Q P + M+P+ Sbjct: 1286 LALPGMGGPGPVGTPDIPLGTAPSM------PGHNPMRPPAFLQQGMMGPHHRMMSPAQS 1339 Query: 1298 ATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLA 1357 P L SN A P R + T P P +P + ++ Sbjct: 1340 TMPGQPTL---------MSNPAAAVGMIPGKDRGP---AGLYTHPGP----VGSPGMMMS 1383 Query: 1358 SQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQN 1400 Q QN+ +P + P +A G F G NP N Sbjct: 1384 MQGMMGPQQNIMIPPQ--MRPRGMAADVGMGGFSQGPG-NPGN 1423 Score = 82.0 bits (201), Expect = 5e-15 Identities = 241/1097 (21%), Positives = 370/1097 (33%), Gaps = 202/1097 (18%) Query: 364 ATVQTPSHPPPP---YPFGSQQASQAHTNF--PQMSNPGQFTAPQMKSLQGGPSRVPTPL 418 AT TP+ P Y F ++ A++A Q+ F + + + S P Sbjct: 163 ATEPTPAQKTPAKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNT 222 Query: 419 QQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNP 478 Q L N P Q +PA+ + ++ P PP P P+ P +P Sbjct: 223 QISALRNDP---KPLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESP 279 Query: 479 MVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTA 538 V+ +P P + P LPP + + PN A Sbjct: 280 GVENKLIP-----SVGSPASSTP-------------LPPDGTGPNSTPN--------NRA 313 Query: 539 TTPGNSGAPQLQANQNVQHAGGQGAGPPQ---------NQMQVSHGPPNM--MQPSLMGI 587 TP + G+ A+ +G P +Q Q+ H ++ ++ + Sbjct: 314 VTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRML 373 Query: 588 HGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNP 647 + SG PQ N + G PQ+ P P Q M Q Q P Sbjct: 374 FPDEKEFTGAQSGGPQQNPGVLDG-PQKKPEG----------PIQAMMAQSQSLGKGPGP 422 Query: 648 MILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLL 707 A PQG +++ SP M PP ++ Q + H M P+ L Sbjct: 423 RTDVGAPFGPQGH-------RDVPFSPDEMVPPS--MNSQSGTIGPDHLDHMTPEQIAWL 473 Query: 708 Q-QNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQM 766 + Q E+ Q Q QQ + Q+ GP ++RGP P Q M G G Sbjct: 474 KLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQ--MTPSEGWAPGGT 531 Query: 767 LPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQT 826 P +N S L P G +PH N S ++ + + Sbjct: 532 EPFSDGINMPHS---------LPPRGMAPH-----------PNMPGSQMRLPGFAGMINS 571 Query: 827 NMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQ----NPG----FP--- 875 M P+V N AS SG + P P+G GQ PG FP Sbjct: 572 EMEGPNVP----NPASRPGLSGVSWPDDVP--KIPDGRNFPPGQGIFSGPGRGERFPNPQ 625 Query: 876 -----------VNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKK 924 K + L + + ++ + ++++ N P + P + Sbjct: 626 GLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGP 685 Query: 925 NSQQDLNTPDTRPAGL---EEADQPPLP-GEQG-----INLDNSGPKLPEFSNRPPGYPS 975 S + P P + E + +P G +G +N+ ++ +P+ P Sbjct: 686 LSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPE 745 Query: 976 QPVEQRP--LQQMPPQLMQHVAPPPQPPQQQ----PQPQLPQQQQPPPPSQPQSQQQQQQ 1029 + ++ RP +P Q P + PQQ+ P+P LP Q P S ++ ++ Sbjct: 746 EMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIG 805 Query: 1030 QQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVP 1089 Q + P LP++ + +P P QR G P+ +S+ G Sbjct: 806 PDQRTNSRLSHMPP----LPLNPSSNPTSLNTAPPVQR----GLGRKPLDISVAGSQVHS 857 Query: 1090 P--SPDKQRMPMPVNTP-LGSNSRKMVYQESPQNPSSSPLAEMASLPEASGS-EAPSVPG 1145 P +P K V +P LGS S + +SPQ PS LA M + P A+ S ++P V G Sbjct: 858 PGINPLKSPTMHQVQSPMLGSPSGNL---KSPQTPSQ--LAGMLAGPAAAASIKSPPVLG 912 Query: 1146 GPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQ 1205 P H+ P P PSP + P Q P +P PN AP Sbjct: 913 SAAASPVHLKSPS--------LPAPSPGWTSSPKPPLQSP--GIP-------PNHKAPL- 954 Query: 1206 TSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPN 1265 ASP PP T S+ +I G P +PP P Sbjct: 955 -------TMASPAMLGNVESGGPPPPTASQPASV-------NIPGSLPSSTPYTMPPEPT 1000 Query: 1266 LNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRAS 1325 L++ NP ++ + S FA P + L + + S+ + S Sbjct: 1001 LSQ-------NPLSI---------MMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARS 1044 Query: 1326 PS-NSRRSSPGSSRKT-TPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLAN 1383 P+ S + PG T P N P TL+ L + N + SP + Sbjct: 1045 PNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSH----SNQMPSPNAVGP 1100 Query: 1384 PPVPGSFPNNSGLNPQN 1400 P P GL N Sbjct: 1101 NIPPHGVPMGPGLMSHN 1117 Score = 52.4 bits (124), Expect = 5e-06 Identities = 242/1195 (20%), Positives = 396/1195 (33%), Gaps = 213/1195 (17%) Query: 822 SIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVT 881 S Q+ + PP V + GN + FS G + P+ C G K Sbjct: 22 SKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPS----PCDSKSGGHTPK--A 75 Query: 882 LTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTP--DTRPAG 939 L P G G+ N N K K+++ Q+D TP D+ Sbjct: 76 LPGP-----------GGSMGLKNGAGNGAKGKGKRERSISADSFDQRDPGTPNDDSDIKE 124 Query: 940 LEEADQPPLPGEQGI--NLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQL------- 990 AD Q ++ S P S+ P + E P Q+ P ++ Sbjct: 125 CNSADHIKSQDSQHTPHSMTPSNATAPR-SSTPSHGQTTATEPTPAQKTPAKVVYVFSTE 183 Query: 991 ---------------------MQHVAPPPQPPQQQP-QPQLPQQQQPPPPSQPQSQQQQQ 1028 +Q+++ P Q+ + P P Q Sbjct: 184 MANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDPKPLPQQPPAPAN 243 Query: 1029 QQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASV 1088 Q Q +Q P P+ P P P + P ++ +P S+ PAS Sbjct: 244 QDQNSSQNTRLQPTP-----PIPAPAPKPAAPPRPLDRESPGVENKLIP---SVGSPASS 295 Query: 1089 PPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPN 1148 P +P P + + + V S + SSS + P S E P++ P+ Sbjct: 296 TP------LPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPD 349 Query: 1149 NMPSHVVLPQNQLMMT---------------------GPKPGPSPLSATQGATPQQPPVN 1187 + + + + + T GP+ P L Q + P+ Sbjct: 350 GLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQ--KKPEGPIQ 407 Query: 1188 SLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLN-- 1245 ++ + T P P P+ P PPS ++ P+ L+ Sbjct: 408 AMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPD--EMVPPSMNSQSGTIGPDHLDHM 465 Query: 1246 --ASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQ------APSNLTMNPSNF 1297 IA L Q R Q L + G P M PS Sbjct: 466 TPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEG 525 Query: 1298 ATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLA 1357 P + S +N +S + +P + PGS + G NS+ + Sbjct: 526 WAPGGTEPFSDGIN---MPHSLPPRGMAP---HPNMPGSQMRLPGFAGMINSEMEGPNVP 579 Query: 1358 SQTNAALLQNVELPRNVLVSPTPLANPPVPG---------SFPNNSGLNPQNSTVSVAAV 1408 + + L V P +V P PP G FPN GL+ + +A Sbjct: 580 NPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLA-- 637 Query: 1409 GGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPN 1468 ++ L +P + + P+ E+ ++P S++ +P + Sbjct: 638 -------EKQLGLPPGMAMEGIR-------------PSMEMNRMIP--GSQRHMEPGNNP 675 Query: 1469 KLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKA 1528 P + L SP+ + P + + + P G+ +V V G + + Sbjct: 676 IFPRIPVEGPL-SPSRGDFPKGIPPQMGPGRELEFGMVPSGMKG-DVNLNVNMGSN---S 730 Query: 1529 SVIP-TLQDLSSSKE------PSNSLNLPHSNELCSSLV--HPELSEVSSNVAPSIPPVM 1579 +IP +++ + E P S LP ++ HP+ E P +P M Sbjct: 731 QMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQ-QEYGMGPRPFLP--M 787 Query: 1580 SRPVSSSS----ISTPLPPNQITVFVTSN----PITTSAN-TSAALPTHLQSALMSTVVT 1630 S+ S+S + P+ P+Q T S+ P+ S+N TS +Q L + Sbjct: 788 SQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLD 847 Query: 1631 MPNAGSKVMVSEGQSAAQSNARPQFITPVFIN-SSSIIQVMKGSQPSTIPAAPLTTNSGL 1689 + AGS+V S G + +S Q +P+ + S ++ SQ + + A P S Sbjct: 848 ISVAGSQVH-SPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIK 906 Query: 1690 MPPSV--AVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLPSPP 1747 PP + A P+H +K S P P +SSP P +Q+ P + + P+ + SP Sbjct: 907 SPPVLGSAAASPVH----LKSPSLPAPSPGWTSSPKPPLQS--PGIPPNHKAPLTMASPA 960 Query: 1748 CTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTM-VSPLLTNSPGSSGN 1806 + V PP P AS + + +LPSS TM P L+ +P S Sbjct: 961 MLGN-VESGGPP--------PPTASQPASVNI-PGSLPSSTPYTMPPEPTLSQNPLS--- 1007 Query: 1807 RRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGAD----GETEGQGLDTTAP 1862 + S+ L A K V S + + G G++T P Sbjct: 1008 ----IMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNP 1063 Query: 1863 GLMGTEQLSTELDSKTPTPPAPTLLKM------TSSPVGPGTASAGPSLPGGALP 1911 + G P P PTL M + S P + GP++P +P Sbjct: 1064 RISG----------PNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGVP 1108 Score = 37.7 bits (86), Expect = 0.12 Identities = 85/462 (18%), Positives = 145/462 (31%), Gaps = 61/462 (13%) Query: 1073 SGSVPVMVSLQGPASVPPSPDKQRMPMP--VNTPLGSNSRKMVYQESPQNPSSSPLAEMA 1130 S + V S G P ++ M P V +P G+ + + S+ ++ + Sbjct: 3 SSNPKVRSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPS 62 Query: 1131 SLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNS-- 1188 SG P GP N G + + P P +S Sbjct: 63 PCDSKSGGHTPKALPGPGGSMGLKNGAGNGAKGKGKRERSISADSFDQRDPGTPNDDSDI 122 Query: 1189 --------LPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISL- 1239 + S H P+ P+ + P+ S P + QT P + + + Sbjct: 123 KECNSADHIKSQDSQHTPHSMTPSNATAPR-----SSTPSHGQTTATEPTPAQKTPAKVV 177 Query: 1240 ---SPERLNASIAGLFPPQINIPLPPR-PNLNRGFDQQGLNP--TTLKAIGQAPSNLTMN 1293 S E N + + Q+ + N++ ++ P T + A+ P L Sbjct: 178 YVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDPKPLPQQ 237 Query: 1294 PSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSR-RSSPGSSRKTTPSPGRQNSKAP 1352 P A + + + + A K A+P R SPG K PS G S P Sbjct: 238 PPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTP 297 Query: 1353 KLTLASQTNAALLQNVELPRNVLVSP------TPLANPPVPGSFPNNSGLNPQNSTVSVA 1406 + N+ P N V+P + A+P P P +SG P Sbjct: 298 LPPDGTGPNST-------PNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPP-------- 342 Query: 1407 AVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSD 1466 + +N + L+ Q + S + +M+ P+++ Q Sbjct: 343 ----TLGENPDGLSQEQLEHRERSLQTLRDIQ-----------RMLFPDEKEFTGAQSGG 387 Query: 1467 PNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPP 1508 P + P V + +A + SQ L P + P Sbjct: 388 PQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAP 429 >gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo sapiens] Length = 2036 Score = 82.0 bits (201), Expect = 5e-15 Identities = 219/1029 (21%), Positives = 357/1029 (34%), Gaps = 157/1029 (15%) Query: 1050 VSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNS 1109 V + PR L+P S P Q S + P P P+ +T + Sbjct: 596 VHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSP 655 Query: 1110 RKMVYQESPQNPSSSPLAEMASL----PEASG---SEAPSVPGGPNNMPSHVVLPQNQLM 1162 P + ++S +E +++ P+ASG S A S G + + P + + Sbjct: 656 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 715 Query: 1163 MTGP----KPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRP-KTPNRASP 1217 T P PG S S T ++P+ P P+S + T S+P T + SP Sbjct: 716 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP 775 Query: 1218 RPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNP 1277 P +E S S R ++ +FP + Sbjct: 776 ------ASTTTPGLSEESTTVYSSSR-GSTETTVFP----------------------HS 806 Query: 1278 TTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGS- 1336 TT G+ P+ P A+ T SG S A SP++++ P + Sbjct: 807 TTTSVHGEEPTTFHSRP---ASTHTTLFTEDSTTSGLTEESTAFP-GSPASTQTGLPATL 862 Query: 1337 -----SRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFP 1391 ++T P S KL+ A T + L+ R +SP+ +PGS P Sbjct: 863 TTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSR---LSPSSTETTTLPGS-P 918 Query: 1392 NNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKM 1451 L+ +++T + P+ D S PA Sbjct: 919 TTPSLSEKSTTFYTS---------------PRSPDATLS--------------PATTTSS 949 Query: 1452 VVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLT 1511 V E+ S QP + + A ++ T+ D S P + G T Sbjct: 950 GVSEESSTSHSQPGSTH------------TTAFPDSTTT----SDLSQEPTTSHSSQGST 993 Query: 1512 DLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNV 1571 + ++P + L + S SS + + LP + + S LV E S + + Sbjct: 994 EATLSPGSTTASSLGQQST-----TFHSSPGDTETTLLP-DDTITSGLV--EASTPTHSS 1045 Query: 1572 APSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTM 1631 S+ ++ P SS+S + +S+ T S + A P + + S + Sbjct: 1046 TGSLHTTLT-PASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSST 1104 Query: 1632 PN---AGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSG 1688 P + S + + + ++ P + S V+ G +P+T P + +T + Sbjct: 1105 PTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVG-EPTTSPISSGSTETT 1163 Query: 1689 LMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLP-SPP 1747 +P S G ++ F S+P P+ + SPA +G V T P S Sbjct: 1164 ALPGSTTTAGLSE--KSTTFYSSPRSPDT-TLSPASTTSSG---VSEESTTSHSRPGSTH 1217 Query: 1748 CTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLT---NSPGSS 1804 T+ P + P V Q E +SP S D P S + + + P T +SPGS+ Sbjct: 1218 TTAFPGSTTMPGVSQ--ESTASHSSP---GSTDTTLSPGSTTASSLGPESTTFHSSPGST 1272 Query: 1805 GNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGL 1864 P +++ L +A V S G T QG TT Sbjct: 1273 ETTLLPDNTTASG----------LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 1322 Query: 1865 MGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSV-RSIVTTLVP 1923 ++ P PP T + S G+ S+ P+ A T++ RS +T V Sbjct: 1323 PSSK-------DTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVH 1375 Query: 1924 SELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTALQAS 1983 S + A TT S + S GLVEE H S +Q + E+ST + ++ Sbjct: 1376 SSPV-ATATTPS-----PARSTTSGLVEESTAYH----SSPGSTQTMHFPESSTASGRSE 1425 Query: 1984 VARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSRPAS 2043 +R +S S +VE+ + + T ES R S + Sbjct: 1426 ESRTSHSSTTHTISSPPSTTSALVEE-PTSYHSSPGSIATTHFPESSTTSGRSEESTASH 1484 Query: 2044 ASSSTKDIT 2052 +S T IT Sbjct: 1485 SSPDTNGIT 1493 Score = 65.9 bits (159), Expect = 4e-10 Identities = 196/889 (22%), Positives = 308/889 (34%), Gaps = 121/889 (13%) Query: 1115 QESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVV---LPQNQLMMTGPKPGPS 1171 +ES + SS LP S PSV G ++ PS + + L + KPG S Sbjct: 65 EESKASHSSPDAMATTVLPAGS---TPSVLVG-DSTPSPISSGSMETTALPGSTTKPGLS 120 Query: 1172 PLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRP-KTPNRASP----RPYYPQTPN 1226 S T ++P+ P LP+S + + T SRP T A P P Q Sbjct: 121 EKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQEST 180 Query: 1227 NRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQA 1286 S P++ +LSP AS G P + G TTL Sbjct: 181 ASHSSPGPTDTTLSPGSTTASSLG-------------PEYTTFHSRPGSTETTL-----L 222 Query: 1287 PSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGR 1346 P N T + A+ H S S +G+T R S + S P SS+ T P+P Sbjct: 223 PDNTTASGLLEASMPVH--SSTRSPHTTLSPAGSTTRQGESTTFHSWP-SSKDTRPAPPT 279 Query: 1347 QNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLN-PQNSTVSV 1405 S + + S + + + + S + S + ++ P++ T S Sbjct: 280 TTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG 339 Query: 1406 AAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPS 1465 G S S ++ S + + P P+ + Sbjct: 340 R---GEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 396 Query: 1466 DPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDL 1525 S + +V PA ++ S LL S T P+ SG Sbjct: 397 STASHSSQDATGTIVLPAR----STTSVLLGES----------------TTSPISSGS-- 434 Query: 1526 KKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSS 1585 + + +P E S + HS+ + S SS V+ SRP Sbjct: 435 METTALPGSTTTPGLSERSTTF---HSSPRSPATTLSPASTTSSGVSEESTTSRSRP--- 488 Query: 1586 SSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQS 1645 S T P+ T S TTS ++ + T L A ST + P+ S S S Sbjct: 489 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA--STTTSGPSQESTTSHSSSGS 546 Query: 1646 AAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQN 1705 T ++ S + G + +T + P +T++ L P S G + Sbjct: 547 -----------TDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTR 595 Query: 1706 IKFSSAPVPPNALS--SSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQV 1763 + SS P LS SS +P +Q + A+ PSPP T++ PV++ Sbjct: 596 V-HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT------APVEES 648 Query: 1764 KELNPDEAS-PQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPV-SSSKGKGKVD 1821 + S P + A T S+ +T + +SP +SG S S++ G+G Sbjct: 649 TTYHRSPGSTPTTHFPASSTTSGHSEKST----IFHSSPDASGTTPSSAHSTTSGRG--- 701 Query: 1822 KIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTP 1881 + T + G + T G TT PGL + ST S +P Sbjct: 702 -----------ESTTSRISPGSTEI-----TTLPG-STTTPGL---SEASTTFYS-SPRS 740 Query: 1882 PAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIA 1941 P TL + + +G G S G+ ++V S +T P + S+ G Sbjct: 741 PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV-SPASTTTPGLSEESTTVYSSSRGSTE 799 Query: 1942 SESLAGGLVEEKVGSHPELLPSIAPSQN--LVSKETSTTAL-QASVARP 1987 + G P S S + L +++++T+ L + S A P Sbjct: 800 TTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP 848 >gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo sapiens] Length = 898 Score = 81.6 bits (200), Expect = 7e-15 Identities = 135/528 (25%), Positives = 194/528 (36%), Gaps = 69/528 (13%) Query: 265 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSG 324 QQQQQQ QQQQQQ QQ QQQQLQ + QQ Q Q Q + Q +P Q P+P S Sbjct: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ--SPPQAPLP----MAVSR 57 Query: 325 ALQPPPAQGSLGTMTANQGWKKAP-LPGPMQQQLQARPSLATVQTPSHPPPPYPFGS--- 380 L P Q L + QG A L G M Q+ L + + PP Y Sbjct: 58 GLPPQQPQQPLLNL---QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTM 114 Query: 381 QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSP 440 A+ + M++PG PS P L P+L P ++ S P Sbjct: 115 PTATLGNLRGYGMASPG----------LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164 Query: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQP--VSSPGRNPMVQQGNVPPNFMVMQQQPPN 498 P +N +Q + R PQ P S + V+ + PP +P Sbjct: 165 VGVP-MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223 Query: 499 QGP--QSLHPGLGGMPKRL------PPGFSAGQANPNFMQGQVPSTTATTPGN-SGAPQL 549 P Q L P + K P A + ++ T PG Q Sbjct: 224 DTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 283 Query: 550 QANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNM 609 QA V Q P + QP ++ + + +Q P++ ++ Sbjct: 284 QARMTVPK---QTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQ-----PRIPSTDT 335 Query: 610 QGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQN 669 Q QP+ +Q + +V Q Q+ P + A+ Q Q V P + + Sbjct: 336 QVQPKLQKQAQTQTSPEHLVLQQKQV----------QPQLQQEAEPQKQVQPQVQPQAHS 385 Query: 670 LGPSPQRMTPPKQMLSQQGPQMM-APHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQF 728 GP ++ + L Q PQ+ H+Q P QV LQ + +Q+ T Q Sbjct: 386 QGPRQVQLQQEAEPLKQVQPQVQPQAHSQ---PPRQVQLQ---LQKQVQTQ----TYPQV 435 Query: 729 NTQNQSNVMP---GPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPV 773 +TQ Q +V P PAQ+ P Q + T + P+Q PV Sbjct: 436 HTQAQPSVQPQEHPPAQV--SVQPPEQTHEQPHTQPQVSLLAPEQTPV 481 Score = 58.5 bits (140), Expect = 6e-08 Identities = 113/483 (23%), Positives = 154/483 (31%), Gaps = 96/483 (19%) Query: 250 RQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQL-----QARPPQQHQQ-------- 296 +Q+ QLQQQQ QQQQ Q QQ QQ Q L + PPQQ QQ Sbjct: 15 QQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGT 74 Query: 297 -----------------QQPQGI----RPQFTAPTQVPVPP--------GWNQLPSGALQ 327 QQ QG+ P T T P G+ G Sbjct: 75 NSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAA 134 Query: 328 PPPAQGSLGTMTANQGWKKA---------PLPGPM----------QQQLQARPSLATVQT 368 P L T Q + +A P+ PM Q QAR S +T Sbjct: 135 PSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPN 194 Query: 369 ---------PSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQ 419 P P GS++A++ P+M P P R P P Sbjct: 195 RKDSSSQTMPVEDKSDPPEGSEEAAE-----PRMDTPEDQDLPPCPEDIAKEKRTPAPEP 249 Query: 420 QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPM 479 +P ++ PA S ++ + P Q Q+ +P +P+ Q +P P Sbjct: 250 EPCEASELPAKRLRSSEEPTEKEPP----GQLQVKAQPQARMTVPKQTQ----TPDLLPE 301 Query: 480 VQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTAT 539 + V P F Q Q P + ++ P + V Sbjct: 302 ALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQV 361 Query: 540 TP--GNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLM-GIHGNMNNQ-- 594 P PQ Q VQ GP Q Q+Q P +QP + H Q Sbjct: 362 QPQLQQEAEPQKQVQPQVQ-PQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420 Query: 595 -----QAGTSGVPQVNLSNMQG-QPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNP-QNP 647 Q T PQV+ QPQ+ PP+Q+ + Q Q L P Q P Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480 Query: 648 MIL 650 +++ Sbjct: 481 VVV 483 Score = 52.0 bits (123), Expect = 6e-06 Identities = 63/270 (23%), Positives = 99/270 (36%), Gaps = 34/270 (12%) Query: 175 RMNNPATVMIPP-GGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPS 233 RM+ P +PP +++ P P PE P S+ L + P Sbjct: 222 RMDTPEDQDLPPCPEDIAKEKRTPAPEPE-------PCEASELPAKRLRSSEEPTEKEPP 274 Query: 234 GSLAPPHHPMQPVSVNRQMNPAN----------FPQLQQQQQQQQQQQQQQQQQQQQQQQ 283 G L P ++V +Q + P+ Q + Q Q Q Q Q Q + Sbjct: 275 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334 Query: 284 QQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQG 343 Q+Q + +Q Q Q P+ Q V P QL A Q + +QG Sbjct: 335 TQVQPKLQKQAQTQ----TSPEHLVLQQKQVQP---QLQQEAEPQKQVQPQVQPQAHSQG 387 Query: 344 WKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHT-NFPQMSNPGQFTAP 402 ++ L + Q +P VQ +H PP Q Q T +PQ+ Q P Sbjct: 388 PRQVQLQQEAEPLKQVQPQ---VQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQ---P 441 Query: 403 QMKSLQGGPSRVPTPLQQPHLTNKSPASSP 432 ++ + P++V +Q P T++ P + P Sbjct: 442 SVQPQEHPPAQV--SVQPPEQTHEQPHTQP 469 Score = 51.2 bits (121), Expect = 1e-05 Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 16/155 (10%) Query: 197 PGPNPELQPRTPRPASQSDAMDPLLSGL-----HIQQQSHPSGSLAPPHHPMQ----PVS 247 P + ++QP+ + A + + L+ +QQ++ P + P P P Sbjct: 331 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQ 390 Query: 248 VNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFT 307 V Q Q+Q Q Q Q Q +Q Q Q Q+Q Q Q PQ H Q QP ++PQ Sbjct: 391 VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTY-PQVHTQAQP-SVQPQEH 448 Query: 308 APTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQ 342 P QV V P P + P Q + + Q Sbjct: 449 PPAQVSVQP-----PEQTHEQPHTQPQVSLLAPEQ 478 Score = 48.9 bits (115), Expect = 5e-05 Identities = 76/291 (26%), Positives = 112/291 (38%), Gaps = 34/291 (11%) Query: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML--MMQQDPKSVRLP--VSQNVHPPR 1058 QQ Q QL QQQQ Q Q QQQQ QQQ ++ L ++QQ P LP VS+ + PP+ Sbjct: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL-PPQ 62 Query: 1059 GP----LNPDSQRMPMQQSGSV----PVMVSLQGP---ASVPPSPDKQRMPMPVNTPLGS 1107 P LN +GS+ ++ LQG A P + D + MP T LG+ Sbjct: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTAT-LGN 121 Query: 1108 NSRKMVYQESPQNPSSSPLAEMAS------LPEAS-----GSEAPSVPGGPNNMPSHVVL 1156 + PS +P ++A+ P+A+ G VP P+ Sbjct: 122 LRGYGMASPGLAAPSLTP-PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 Query: 1157 PQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRAS 1216 PQ Q T P+ ++ P + + S P + P P P + Sbjct: 181 PQKQ-ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239 Query: 1217 PRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPP-QINIPLPPRPNL 1266 +TP P E SE+ R + PP Q+ + P+ + Sbjct: 240 KE---KRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 287 Score = 47.8 bits (112), Expect = 1e-04 Identities = 110/499 (22%), Positives = 171/499 (34%), Gaps = 94/499 (18%) Query: 683 MLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQ 742 M SQQ Q + Q + Q LQQ + +Q + Q+Q QQ Q P P Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-QLQQLLQQSPPQ-----APLPMA 54 Query: 743 IMRG-PTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQG--QVLRPPG------- 792 + RG P Q ++ G S +L G + + +QG Q PP Sbjct: 55 VSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGLDQFAMPPATYDTAGL 112 Query: 793 ---------------PSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHV---- 833 SP +A P A +L Q P + +Q+ + PP V Sbjct: 113 TMPTATLGNLRGYGMASPGLAAPSLTPPQLAT--PNLQQFFPQAT-RQSLLGPPPVGVPM 169 Query: 834 --------------QAMQGNSASGNHFSGHGMSFNA-PFSGAPNGNQ------MSCGQNP 872 QA +S + N + S P G++ M ++ Sbjct: 170 NPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ 229 Query: 873 GFP-----VNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKP---KKKKPPRKKK 924 P + K+ +P S++ A + + + T P + K P+ + Sbjct: 230 DLPPCPEDIAKEKRTPAPEPEPCEASELPAKR--LRSSEEPTEKEPPGQLQVKAQPQARM 287 Query: 925 NSQQDLNTPDTRPAGLE----EADQPPLPGEQGINLDNSGPKLPEFSNR-PPGYPSQPVE 979 + TPD P LE QP + Q + P++P + P Q Sbjct: 288 TVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQT 347 Query: 980 QR-------PLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQ 1032 Q +Q+ PQL Q PQ+Q QPQ+ Q P Q Q QQ+ + +Q Sbjct: 348 QTSPEHLVLQQKQVQPQLQQEA-----EPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQ 402 Query: 1033 MMMMLMMQ---QDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVP 1089 + + Q Q P+ V+L + + V P + +Q P VS+Q P Sbjct: 403 VQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTH 462 Query: 1090 PSPDKQ---RMPMPVNTPL 1105 P Q + P TP+ Sbjct: 463 EQPHTQPQVSLLAPEQTPV 481 Score = 43.5 bits (101), Expect = 0.002 Identities = 31/117 (26%), Positives = 48/117 (41%), Gaps = 7/117 (5%) Query: 199 PNPELQPRT-PRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANF 257 P ++QP+ P+ SQ + +QQ++ P + P P RQ+ Sbjct: 371 PQKQVQPQVQPQAHSQGPRQ------VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQ 424 Query: 258 PQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPV 314 Q+Q Q Q Q Q Q Q+ Q+ +PP+Q +Q + AP Q PV Sbjct: 425 KQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 481 Score = 41.2 bits (95), Expect = 0.011 Identities = 125/593 (21%), Positives = 199/593 (33%), Gaps = 100/593 (16%) Query: 1019 SQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPV 1078 SQ Q QQ QQQQQQ+ + Q Q+ +QQ + + Sbjct: 3 SQQQQQQLQQQQQQLQQLQQQQ------------------------LQQQQLQQQQLLQL 38 Query: 1079 MVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGS 1138 LQ SP + +PM V+ L PQ P PL + G+ Sbjct: 39 QQLLQ------QSPPQAPLPMAVSRGL-----------PPQQP-QQPLLNL------QGT 74 Query: 1139 EAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP 1198 + S+ G +M +L Q QL P T G T + +L +G P Sbjct: 75 NSASLLNG--SMLQRALLLQ-QLQGLDQFAMPPATYDTAGLTMPTATLGNL-RGYGMASP 130 Query: 1199 NVAAPTQTSRPKTPNRASP--RPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQI 1256 +AAP+ T P A+P + ++PQ P + ++P + N S PQ Sbjct: 131 GLAAPSLT----PPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN---PQK 183 Query: 1257 NIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQS 1316 NR P K+ S P TP+ L + K+ Sbjct: 184 QARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP-RMDTPEDQDLPPCPEDIAKEK 242 Query: 1317 NSGATK----RASPSNSRRSSPGSSRKTTPSPGRQNSKA---PKLTLASQTNAALLQNVE 1369 + A + AS ++R PG+ KA ++T+ QT L Sbjct: 243 RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDL---- 298 Query: 1370 LPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQN 1429 LP + P P V L Q S D + + + + Q Sbjct: 299 LPEALEAQVLPRFQPRV---------LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 349 Query: 1430 S------QSRKEQVNIELKAVPAQEVKMVVPEDQSKKDG-------QPSDPNKLPSVEEN 1476 S Q ++ Q ++ +A P ++V+ V + Q+ G Q ++P K + Sbjct: 350 SPEHLVLQQKQVQPQLQQEAEPQKQVQPQV-QPQAHSQGPRQVQLQQEAEPLKQVQPQVQ 408 Query: 1477 KNLVSPAMREAPTSLSQLLDNSGAPNV-TIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQ 1535 S R+ L + + P V T P + E P VS + ++ P Q Sbjct: 409 PQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 468 Query: 1536 DLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSI 1588 S P + + H +C + P+ E + ++P + VS I Sbjct: 469 PQVSLLAPEQTPVVVH---VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEI 518 Score = 39.3 bits (90), Expect = 0.040 Identities = 110/513 (21%), Positives = 173/513 (33%), Gaps = 102/513 (19%) Query: 591 MNNQQAGTSGVPQVNLSNMQGQPQQGPPSQL--MGMHQQIVPSQGQ--MVQQQGTLNPQ- 645 + QQ + Q L +Q QQ PP M + + + P Q Q ++ QGT + Sbjct: 20 LQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASL 79 Query: 646 -NPMILSRAQLMPQGQMM--------------VNPPSQNLG-------PSPQRMTPPKQM 683 N +L RA L+ Q Q + + P+ LG SP P Sbjct: 80 LNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAP---- 135 Query: 684 LSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQI 743 S PQ+ P+ Q PQ P + N Q N N Q Q A+ Sbjct: 136 -SLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQ-------ART 187 Query: 744 MRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRP-----------PG 792 TPN + + Q T + + P +G + ++ + Q L P P Sbjct: 188 SSSTTPNRKDSSSQ-TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPA 246 Query: 793 PSPHMAQQHGDPATTANNDVSLSQMMPDVSIQ-----QTNMVPPHV--------QAMQGN 839 P P + PA + ++ P +Q Q M P +A++ Sbjct: 247 PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQ 306 Query: 840 SASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGH 899 F + A Q+ P P T P L Q+ S H Sbjct: 307 VLP--RFQPRVLQVQA---------QVQSQTQPRIPSTD--TQVQPKLQKQAQTQTSPEH 353 Query: 900 FGVNNKQNNTNANK---PKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINL 956 + KQ + P+K+ P+ Q ++ R L++ +P L Sbjct: 354 LVLQQKQVQPQLQQEAEPQKQVQPQV----QPQAHSQGPRQVQLQQEAEP---------L 400 Query: 957 DNSGPKL-PEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP 1015 P++ P+ ++PP ++++ Q PQ+ P Q PQ+ P P Q Sbjct: 401 KQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQ-PQEHP----PAQVSV 455 Query: 1016 PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRL 1048 PP Q Q Q Q + +L +Q P V + Sbjct: 456 QPPEQTHEQPHTQPQ---VSLLAPEQTPVVVHV 485 Score = 38.5 bits (88), Expect = 0.069 Identities = 61/305 (20%), Positives = 104/305 (34%), Gaps = 31/305 (10%) Query: 976 QPVEQRPLQQ---MPPQLMQHVAPPPQPPQQQPQPQLPQQQQPP-PPSQPQSQQQQQQQQ 1031 Q ++Q+ LQQ QL+Q Q P Q P P + PP P QP Q Sbjct: 18 QQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSA 77 Query: 1032 QMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSV----PVMVSLQGPAS 1087 ++ M+Q+ +L P + MP G++ L P+ Sbjct: 78 SLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSL 137 Query: 1088 VPP---SPDKQRM-----------PMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLP 1133 PP +P+ Q+ P PV P+ + + S +NP ++ P Sbjct: 138 TPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQ----FNLSGRNPQKQARTSSSTTP 193 Query: 1134 EASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSH 1193 S + ++P + P + M P+ P A ++ P Sbjct: 194 NRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCE 253 Query: 1194 GHHFP--NVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGL 1251 P + + + + + P + + PQ P T+ + L PE L A + Sbjct: 254 ASELPAKRLRSSEEPTEKEPPGQLQVKA-QPQARMTVPKQTQTPD--LLPEALEAQVLPR 310 Query: 1252 FPPQI 1256 F P++ Sbjct: 311 FQPRV 315 >gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo sapiens] Length = 898 Score = 81.6 bits (200), Expect = 7e-15 Identities = 135/528 (25%), Positives = 194/528 (36%), Gaps = 69/528 (13%) Query: 265 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSG 324 QQQQQQ QQQQQQ QQ QQQQLQ + QQ Q Q Q + Q +P Q P+P S Sbjct: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ--SPPQAPLP----MAVSR 57 Query: 325 ALQPPPAQGSLGTMTANQGWKKAP-LPGPMQQQLQARPSLATVQTPSHPPPPYPFGS--- 380 L P Q L + QG A L G M Q+ L + + PP Y Sbjct: 58 GLPPQQPQQPLLNL---QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTM 114 Query: 381 QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSP 440 A+ + M++PG PS P L P+L P ++ S P Sbjct: 115 PTATLGNLRGYGMASPG----------LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164 Query: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQP--VSSPGRNPMVQQGNVPPNFMVMQQQPPN 498 P +N +Q + R PQ P S + V+ + PP +P Sbjct: 165 VGVP-MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223 Query: 499 QGP--QSLHPGLGGMPKRL------PPGFSAGQANPNFMQGQVPSTTATTPGN-SGAPQL 549 P Q L P + K P A + ++ T PG Q Sbjct: 224 DTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 283 Query: 550 QANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNM 609 QA V Q P + QP ++ + + +Q P++ ++ Sbjct: 284 QARMTVPK---QTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQ-----PRIPSTDT 335 Query: 610 QGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQN 669 Q QP+ +Q + +V Q Q+ P + A+ Q Q V P + + Sbjct: 336 QVQPKLQKQAQTQTSPEHLVLQQKQV----------QPQLQQEAEPQKQVQPQVQPQAHS 385 Query: 670 LGPSPQRMTPPKQMLSQQGPQMM-APHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQF 728 GP ++ + L Q PQ+ H+Q P QV LQ + +Q+ T Q Sbjct: 386 QGPRQVQLQQEAEPLKQVQPQVQPQAHSQ---PPRQVQLQ---LQKQVQTQ----TYPQV 435 Query: 729 NTQNQSNVMP---GPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPV 773 +TQ Q +V P PAQ+ P Q + T + P+Q PV Sbjct: 436 HTQAQPSVQPQEHPPAQV--SVQPPEQTHEQPHTQPQVSLLAPEQTPV 481 Score = 58.5 bits (140), Expect = 6e-08 Identities = 113/483 (23%), Positives = 154/483 (31%), Gaps = 96/483 (19%) Query: 250 RQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQL-----QARPPQQHQQ-------- 296 +Q+ QLQQQQ QQQQ Q QQ QQ Q L + PPQQ QQ Sbjct: 15 QQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGT 74 Query: 297 -----------------QQPQGI----RPQFTAPTQVPVPP--------GWNQLPSGALQ 327 QQ QG+ P T T P G+ G Sbjct: 75 NSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAA 134 Query: 328 PPPAQGSLGTMTANQGWKKA---------PLPGPM----------QQQLQARPSLATVQT 368 P L T Q + +A P+ PM Q QAR S +T Sbjct: 135 PSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPN 194 Query: 369 ---------PSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQ 419 P P GS++A++ P+M P P R P P Sbjct: 195 RKDSSSQTMPVEDKSDPPEGSEEAAE-----PRMDTPEDQDLPPCPEDIAKEKRTPAPEP 249 Query: 420 QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPM 479 +P ++ PA S ++ + P Q Q+ +P +P+ Q +P P Sbjct: 250 EPCEASELPAKRLRSSEEPTEKEPP----GQLQVKAQPQARMTVPKQTQ----TPDLLPE 301 Query: 480 VQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTAT 539 + V P F Q Q P + ++ P + V Sbjct: 302 ALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQV 361 Query: 540 TP--GNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLM-GIHGNMNNQ-- 594 P PQ Q VQ GP Q Q+Q P +QP + H Q Sbjct: 362 QPQLQQEAEPQKQVQPQVQ-PQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420 Query: 595 -----QAGTSGVPQVNLSNMQG-QPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNP-QNP 647 Q T PQV+ QPQ+ PP+Q+ + Q Q L P Q P Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480 Query: 648 MIL 650 +++ Sbjct: 481 VVV 483 Score = 52.0 bits (123), Expect = 6e-06 Identities = 63/270 (23%), Positives = 99/270 (36%), Gaps = 34/270 (12%) Query: 175 RMNNPATVMIPP-GGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPS 233 RM+ P +PP +++ P P PE P S+ L + P Sbjct: 222 RMDTPEDQDLPPCPEDIAKEKRTPAPEPE-------PCEASELPAKRLRSSEEPTEKEPP 274 Query: 234 GSLAPPHHPMQPVSVNRQMNPAN----------FPQLQQQQQQQQQQQQQQQQQQQQQQQ 283 G L P ++V +Q + P+ Q + Q Q Q Q Q Q + Sbjct: 275 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334 Query: 284 QQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQG 343 Q+Q + +Q Q Q P+ Q V P QL A Q + +QG Sbjct: 335 TQVQPKLQKQAQTQ----TSPEHLVLQQKQVQP---QLQQEAEPQKQVQPQVQPQAHSQG 387 Query: 344 WKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHT-NFPQMSNPGQFTAP 402 ++ L + Q +P VQ +H PP Q Q T +PQ+ Q P Sbjct: 388 PRQVQLQQEAEPLKQVQPQ---VQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQ---P 441 Query: 403 QMKSLQGGPSRVPTPLQQPHLTNKSPASSP 432 ++ + P++V +Q P T++ P + P Sbjct: 442 SVQPQEHPPAQV--SVQPPEQTHEQPHTQP 469 Score = 51.2 bits (121), Expect = 1e-05 Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 16/155 (10%) Query: 197 PGPNPELQPRTPRPASQSDAMDPLLSGL-----HIQQQSHPSGSLAPPHHPMQ----PVS 247 P + ++QP+ + A + + L+ +QQ++ P + P P P Sbjct: 331 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQ 390 Query: 248 VNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFT 307 V Q Q+Q Q Q Q Q +Q Q Q Q+Q Q Q PQ H Q QP ++PQ Sbjct: 391 VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTY-PQVHTQAQP-SVQPQEH 448 Query: 308 APTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQ 342 P QV V P P + P Q + + Q Sbjct: 449 PPAQVSVQP-----PEQTHEQPHTQPQVSLLAPEQ 478 Score = 48.9 bits (115), Expect = 5e-05 Identities = 76/291 (26%), Positives = 112/291 (38%), Gaps = 34/291 (11%) Query: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML--MMQQDPKSVRLP--VSQNVHPPR 1058 QQ Q QL QQQQ Q Q QQQQ QQQ ++ L ++QQ P LP VS+ + PP+ Sbjct: 4 QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL-PPQ 62 Query: 1059 GP----LNPDSQRMPMQQSGSV----PVMVSLQGP---ASVPPSPDKQRMPMPVNTPLGS 1107 P LN +GS+ ++ LQG A P + D + MP T LG+ Sbjct: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTAT-LGN 121 Query: 1108 NSRKMVYQESPQNPSSSPLAEMAS------LPEAS-----GSEAPSVPGGPNNMPSHVVL 1156 + PS +P ++A+ P+A+ G VP P+ Sbjct: 122 LRGYGMASPGLAAPSLTP-PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180 Query: 1157 PQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRAS 1216 PQ Q T P+ ++ P + + S P + P P P + Sbjct: 181 PQKQ-ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239 Query: 1217 PRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPP-QINIPLPPRPNL 1266 +TP P E SE+ R + PP Q+ + P+ + Sbjct: 240 KE---KRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 287 Score = 47.8 bits (112), Expect = 1e-04 Identities = 110/499 (22%), Positives = 171/499 (34%), Gaps = 94/499 (18%) Query: 683 MLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQ 742 M SQQ Q + Q + Q LQQ + +Q + Q+Q QQ Q P P Sbjct: 1 MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-QLQQLLQQSPPQ-----APLPMA 54 Query: 743 IMRG-PTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQG--QVLRPPG------- 792 + RG P Q ++ G S +L G + + +QG Q PP Sbjct: 55 VSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGLDQFAMPPATYDTAGL 112 Query: 793 ---------------PSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHV---- 833 SP +A P A +L Q P + +Q+ + PP V Sbjct: 113 TMPTATLGNLRGYGMASPGLAAPSLTPPQLAT--PNLQQFFPQAT-RQSLLGPPPVGVPM 169 Query: 834 --------------QAMQGNSASGNHFSGHGMSFNA-PFSGAPNGNQ------MSCGQNP 872 QA +S + N + S P G++ M ++ Sbjct: 170 NPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ 229 Query: 873 GFP-----VNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKP---KKKKPPRKKK 924 P + K+ +P S++ A + + + T P + K P+ + Sbjct: 230 DLPPCPEDIAKEKRTPAPEPEPCEASELPAKR--LRSSEEPTEKEPPGQLQVKAQPQARM 287 Query: 925 NSQQDLNTPDTRPAGLE----EADQPPLPGEQGINLDNSGPKLPEFSNR-PPGYPSQPVE 979 + TPD P LE QP + Q + P++P + P Q Sbjct: 288 TVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQT 347 Query: 980 QR-------PLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQ 1032 Q +Q+ PQL Q PQ+Q QPQ+ Q P Q Q QQ+ + +Q Sbjct: 348 QTSPEHLVLQQKQVQPQLQQEA-----EPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQ 402 Query: 1033 MMMMLMMQ---QDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVP 1089 + + Q Q P+ V+L + + V P + +Q P VS+Q P Sbjct: 403 VQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTH 462 Query: 1090 PSPDKQ---RMPMPVNTPL 1105 P Q + P TP+ Sbjct: 463 EQPHTQPQVSLLAPEQTPV 481 Score = 43.5 bits (101), Expect = 0.002 Identities = 31/117 (26%), Positives = 48/117 (41%), Gaps = 7/117 (5%) Query: 199 PNPELQPRT-PRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANF 257 P ++QP+ P+ SQ + +QQ++ P + P P RQ+ Sbjct: 371 PQKQVQPQVQPQAHSQGPRQ------VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQ 424 Query: 258 PQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPV 314 Q+Q Q Q Q Q Q Q+ Q+ +PP+Q +Q + AP Q PV Sbjct: 425 KQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 481 Score = 41.2 bits (95), Expect = 0.011 Identities = 125/593 (21%), Positives = 199/593 (33%), Gaps = 100/593 (16%) Query: 1019 SQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPV 1078 SQ Q QQ QQQQQQ+ + Q Q+ +QQ + + Sbjct: 3 SQQQQQQLQQQQQQLQQLQQQQ------------------------LQQQQLQQQQLLQL 38 Query: 1079 MVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGS 1138 LQ SP + +PM V+ L PQ P PL + G+ Sbjct: 39 QQLLQ------QSPPQAPLPMAVSRGL-----------PPQQP-QQPLLNL------QGT 74 Query: 1139 EAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP 1198 + S+ G +M +L Q QL P T G T + +L +G P Sbjct: 75 NSASLLNG--SMLQRALLLQ-QLQGLDQFAMPPATYDTAGLTMPTATLGNL-RGYGMASP 130 Query: 1199 NVAAPTQTSRPKTPNRASP--RPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQI 1256 +AAP+ T P A+P + ++PQ P + ++P + N S PQ Sbjct: 131 GLAAPSLT----PPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN---PQK 183 Query: 1257 NIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQS 1316 NR P K+ S P TP+ L + K+ Sbjct: 184 QARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP-RMDTPEDQDLPPCPEDIAKEK 242 Query: 1317 NSGATK----RASPSNSRRSSPGSSRKTTPSPGRQNSKA---PKLTLASQTNAALLQNVE 1369 + A + AS ++R PG+ KA ++T+ QT L Sbjct: 243 RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDL---- 298 Query: 1370 LPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQN 1429 LP + P P V L Q S D + + + + Q Sbjct: 299 LPEALEAQVLPRFQPRV---------LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 349 Query: 1430 S------QSRKEQVNIELKAVPAQEVKMVVPEDQSKKDG-------QPSDPNKLPSVEEN 1476 S Q ++ Q ++ +A P ++V+ V + Q+ G Q ++P K + Sbjct: 350 SPEHLVLQQKQVQPQLQQEAEPQKQVQPQV-QPQAHSQGPRQVQLQQEAEPLKQVQPQVQ 408 Query: 1477 KNLVSPAMREAPTSLSQLLDNSGAPNV-TIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQ 1535 S R+ L + + P V T P + E P VS + ++ P Q Sbjct: 409 PQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 468 Query: 1536 DLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSI 1588 S P + + H +C + P+ E + ++P + VS I Sbjct: 469 PQVSLLAPEQTPVVVH---VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEI 518 Score = 39.3 bits (90), Expect = 0.040 Identities = 110/513 (21%), Positives = 173/513 (33%), Gaps = 102/513 (19%) Query: 591 MNNQQAGTSGVPQVNLSNMQGQPQQGPPSQL--MGMHQQIVPSQGQ--MVQQQGTLNPQ- 645 + QQ + Q L +Q QQ PP M + + + P Q Q ++ QGT + Sbjct: 20 LQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASL 79 Query: 646 -NPMILSRAQLMPQGQMM--------------VNPPSQNLG-------PSPQRMTPPKQM 683 N +L RA L+ Q Q + + P+ LG SP P Sbjct: 80 LNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAP---- 135 Query: 684 LSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQI 743 S PQ+ P+ Q PQ P + N Q N N Q Q A+ Sbjct: 136 -SLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQ-------ART 187 Query: 744 MRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRP-----------PG 792 TPN + + Q T + + P +G + ++ + Q L P P Sbjct: 188 SSSTTPNRKDSSSQ-TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPA 246 Query: 793 PSPHMAQQHGDPATTANNDVSLSQMMPDVSIQ-----QTNMVPPHV--------QAMQGN 839 P P + PA + ++ P +Q Q M P +A++ Sbjct: 247 PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQ 306 Query: 840 SASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGH 899 F + A Q+ P P T P L Q+ S H Sbjct: 307 VLP--RFQPRVLQVQA---------QVQSQTQPRIPSTD--TQVQPKLQKQAQTQTSPEH 353 Query: 900 FGVNNKQNNTNANK---PKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINL 956 + KQ + P+K+ P+ Q ++ R L++ +P L Sbjct: 354 LVLQQKQVQPQLQQEAEPQKQVQPQV----QPQAHSQGPRQVQLQQEAEP---------L 400 Query: 957 DNSGPKL-PEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP 1015 P++ P+ ++PP ++++ Q PQ+ P Q PQ+ P P Q Sbjct: 401 KQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQ-PQEHP----PAQVSV 455 Query: 1016 PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRL 1048 PP Q Q Q Q + +L +Q P V + Sbjct: 456 QPPEQTHEQPHTQPQ---VSLLAPEQTPVVVHV 485 Score = 38.5 bits (88), Expect = 0.069 Identities = 61/305 (20%), Positives = 104/305 (34%), Gaps = 31/305 (10%) Query: 976 QPVEQRPLQQ---MPPQLMQHVAPPPQPPQQQPQPQLPQQQQPP-PPSQPQSQQQQQQQQ 1031 Q ++Q+ LQQ QL+Q Q P Q P P + PP P QP Q Sbjct: 18 QQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSA 77 Query: 1032 QMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSV----PVMVSLQGPAS 1087 ++ M+Q+ +L P + MP G++ L P+ Sbjct: 78 SLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSL 137 Query: 1088 VPP---SPDKQRM-----------PMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLP 1133 PP +P+ Q+ P PV P+ + + S +NP ++ P Sbjct: 138 TPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQ----FNLSGRNPQKQARTSSSTTP 193 Query: 1134 EASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSH 1193 S + ++P + P + M P+ P A ++ P Sbjct: 194 NRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCE 253 Query: 1194 GHHFP--NVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGL 1251 P + + + + + P + + PQ P T+ + L PE L A + Sbjct: 254 ASELPAKRLRSSEEPTEKEPPGQLQVKA-QPQARMTVPKQTQTPD--LLPEALEAQVLPR 310 Query: 1252 FPPQI 1256 F P++ Sbjct: 311 FQPRV 315 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.125 0.358 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 104,133,539 Number of Sequences: 37866 Number of extensions: 6776856 Number of successful extensions: 89913 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 545 Number of HSP's successfully gapped in prelim test: 1865 Number of HSP's that attempted gapping in prelim test: 33075 Number of HSP's gapped (non-prelim): 27186 length of query: 2063 length of database: 18,247,518 effective HSP length: 118 effective length of query: 1945 effective length of database: 13,779,330 effective search space: 26800796850 effective search space used: 26800796850 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.