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Search of human proteins with 31543452
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31543452 PX domain containing serine/threonine kinase [Homo
sapiens]
(578 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31543452 PX domain containing serine/threonine kinase [Homo s... 1162 0.0
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 64 3e-10
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 64 3e-10
gi|23238244 sorting nexin 16 isoform a [Homo sapiens] 61 2e-09
gi|23238246 sorting nexin 16 isoform a [Homo sapiens] 61 2e-09
gi|17864088 sorting nexin 13 [Homo sapiens] 54 4e-07
gi|195947369 junction-mediating and regulatory protein [Homo sap... 54 5e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 53 9e-07
gi|150378539 piccolo isoform 1 [Homo sapiens] 53 9e-07
gi|24797143 sorting nexin 14 isoform b [Homo sapiens] 52 2e-06
gi|24797145 sorting nexin 14 isoform a [Homo sapiens] 52 2e-06
gi|154091028 sorting nexin 29 [Homo sapiens] 52 2e-06
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 51 3e-06
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 51 3e-06
gi|39812378 RAN binding protein 9 [Homo sapiens] 50 4e-06
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 50 4e-06
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 50 4e-06
gi|66472382 nischarin [Homo sapiens] 50 4e-06
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 50 6e-06
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 50 6e-06
gi|4885563 protein kinase C, epsilon [Homo sapiens] 50 7e-06
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 50 7e-06
gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [H... 50 7e-06
gi|23943858 sorting nexin 8 [Homo sapiens] 49 1e-05
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 49 1e-05
gi|47132519 Ras association and pleckstrin homology domains 1 is... 49 2e-05
gi|52485606 formin-like 2 [Homo sapiens] 48 2e-05
gi|38492356 DNA-directed DNA polymerase delta 3 [Homo sapiens] 48 3e-05
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 48 3e-05
gi|148613878 acrosin precursor [Homo sapiens] 48 3e-05
>gi|31543452 PX domain containing serine/threonine kinase [Homo
sapiens]
Length = 578
Score = 1162 bits (3005), Expect = 0.0
Identities = 578/578 (100%), Positives = 578/578 (100%)
Query: 1 MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFD 60
MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFD
Sbjct: 1 MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFD 60
Query: 61 LLNNSLQIAGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFLD 120
LLNNSLQIAGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFLD
Sbjct: 61 LLNNSLQIAGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFLD 120
Query: 121 PNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSW 180
PNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSW
Sbjct: 121 PNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSW 180
Query: 181 ADLGPDKYLSDKDFQCLIKLLPSCLHPYIYRVTFATANESSALLIRMFNEKGTLKDLIYK 240
ADLGPDKYLSDKDFQCLIKLLPSCLHPYIYRVTFATANESSALLIRMFNEKGTLKDLIYK
Sbjct: 181 ADLGPDKYLSDKDFQCLIKLLPSCLHPYIYRVTFATANESSALLIRMFNEKGTLKDLIYK 240
Query: 241 AKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNVMLDGDT 300
AKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNVMLDGDT
Sbjct: 241 AKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNVMLDGDT 300
Query: 301 CRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFP 360
CRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFP
Sbjct: 301 CRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFP 360
Query: 361 PAPSMAVVAVLESTLSCEACKNGMPTISRLLQMPLFSDVLLTTSEKPQFKIPTKLKEALR 420
PAPSMAVVAVLESTLSCEACKNGMPTISRLLQMPLFSDVLLTTSEKPQFKIPTKLKEALR
Sbjct: 361 PAPSMAVVAVLESTLSCEACKNGMPTISRLLQMPLFSDVLLTTSEKPQFKIPTKLKEALR 420
Query: 421 IAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSA 480
IAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSA
Sbjct: 421 IAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSA 480
Query: 481 KYSNSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQLS 540
KYSNSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQLS
Sbjct: 481 KYSNSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQLS 540
Query: 541 SQAVNGMSRGALLSSIQNFQKGTLRKAKTCDHSAPKIG 578
SQAVNGMSRGALLSSIQNFQKGTLRKAKTCDHSAPKIG
Sbjct: 541 SQAVNGMSRGALLSSIQNFQKGTLRKAKTCDHSAPKIG 578
>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 64.3 bits (155), Expect = 3e-10
Identities = 86/370 (23%), Positives = 141/370 (38%), Gaps = 59/370 (15%)
Query: 17 TVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSL--QIAGLSLP 74
+V + ++ E + + T Y + V G S W + RRY++FD L N+L Q ++L
Sbjct: 15 SVSIPSSDEHREKKKRFTVYKVLVSVGRS---EWFVFRRYAEFDKLYNTLKKQFPAMALK 71
Query: 75 LPPKKLIG-NMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFL---------DPNNY 124
+P K++ G N D +FI +R+ GL ++ + L N V+ FL DP+
Sbjct: 72 IPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSED 131
Query: 125 SANYTEIALQQVSMFFRSEP------KWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVL 178
+ L S P K + LK IG K L K K K V
Sbjct: 132 EDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAV- 190
Query: 179 SWADLGPDKYLSDKDFQCLIK----LLPSCLHPYIYRVTFATANESSALLIRMFNEKGTL 234
L L+ K+ + ++ LL + HP++ + ++ + F G L
Sbjct: 191 --KVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGEL 248
Query: 235 KDLIYKAKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNV 294
+ + ++ + + + Y +I L +LH Y L N+
Sbjct: 249 ----------------FFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENI 292
Query: 295 MLDG-------------DTCRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHL 341
+LD + + D + G P + RK +VD C G +
Sbjct: 293 LLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAP--EVIRKQPYDNTVDWWCLGAV 350
Query: 342 LYEMTYGRPP 351
LYEM YG PP
Sbjct: 351 LYEMLYGLPP 360
>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 64.3 bits (155), Expect = 3e-10
Identities = 86/370 (23%), Positives = 141/370 (38%), Gaps = 59/370 (15%)
Query: 17 TVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSL--QIAGLSLP 74
+V + ++ E + + T Y + V G S W + RRY++FD L N+L Q ++L
Sbjct: 15 SVSIPSSDEHREKKKRFTVYKVLVSVGRS---EWFVFRRYAEFDKLYNTLKKQFPAMALK 71
Query: 75 LPPKKLIG-NMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFL---------DPNNY 124
+P K++ G N D +FI +R+ GL ++ + L N V+ FL DP+
Sbjct: 72 IPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSED 131
Query: 125 SANYTEIALQQVSMFFRSEP------KWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVL 178
+ L S P K + LK IG K L K K K V
Sbjct: 132 EDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAV- 190
Query: 179 SWADLGPDKYLSDKDFQCLIK----LLPSCLHPYIYRVTFATANESSALLIRMFNEKGTL 234
L L+ K+ + ++ LL + HP++ + ++ + F G L
Sbjct: 191 --KVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGEL 248
Query: 235 KDLIYKAKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNV 294
+ + ++ + + + Y +I L +LH Y L N+
Sbjct: 249 ----------------FFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENI 292
Query: 295 MLDG-------------DTCRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHL 341
+LD + + D + G P + RK +VD C G +
Sbjct: 293 LLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAP--EVIRKQPYDNTVDWWCLGAV 350
Query: 342 LYEMTYGRPP 351
LYEM YG PP
Sbjct: 351 LYEMLYGLPP 360
>gi|23238244 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/106 (33%), Positives = 57/106 (53%), Gaps = 5/106 (4%)
Query: 17 TVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQ--IAGLSLP 74
+ P E + T Y I V++ + E SW + RRY+DF LN+ L+ G L
Sbjct: 108 STPTILGYEVMEERAKFTVYKILVKK--TPEESWVVFRRYTDFSRLNDKLKEMFPGFRLA 165
Query: 75 LPPKKLI-GNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFL 119
LPPK+ N + +F+ +RQ GLQ +L + + ++NC V++FL
Sbjct: 166 LPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFL 211
>gi|23238246 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/106 (33%), Positives = 57/106 (53%), Gaps = 5/106 (4%)
Query: 17 TVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQ--IAGLSLP 74
+ P E + T Y I V++ + E SW + RRY+DF LN+ L+ G L
Sbjct: 108 STPTILGYEVMEERAKFTVYKILVKK--TPEESWVVFRRYTDFSRLNDKLKEMFPGFRLA 165
Query: 75 LPPKKLI-GNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFL 119
LPPK+ N + +F+ +RQ GLQ +L + + ++NC V++FL
Sbjct: 166 LPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFL 211
>gi|17864088 sorting nexin 13 [Homo sapiens]
Length = 957
Score = 53.9 bits (128), Expect = 4e-07
Identities = 43/131 (32%), Positives = 63/131 (48%), Gaps = 13/131 (9%)
Query: 15 DDTVPLTAAIEASQSLQSHTE----YIIRV-QRGISVENSWQIVRRYSDFDLLNNSL--Q 67
DD+V L A I + H + Y I V +R ++ E W+ RRYSDF + + Q
Sbjct: 556 DDSVQLHAYISDTGVCNDHGKTYALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQ 615
Query: 68 IAGLS--LPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHIL----SNCELVKKFLDP 121
LS L LP KK NMDR+F+ +R+K L YL ++ ++ + V FL+
Sbjct: 616 FESLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMKASPALAHYVYDFLEN 675
Query: 122 NNYSANYTEIA 132
YS + A
Sbjct: 676 KAYSKGKGDFA 686
>gi|195947369 junction-mediating and regulatory protein [Homo
sapiens]
Length = 988
Score = 53.5 bits (127), Expect = 5e-07
Identities = 27/56 (48%), Positives = 29/56 (51%), Gaps = 8/56 (14%)
Query: 484 NSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQL 539
N+N S +PL SP PTPP PPPPPPPPPP PLP A P L
Sbjct: 790 NNNLEPCSVTINPLPSPLPPTPP--------PPPPPPPPPPPPPLPVAKDSGPETL 837
Score = 36.2 bits (82), Expect = 0.085
Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 14/101 (13%)
Query: 457 KKRKILARKKSKRSALENSEEHS-AKYSNSNNSAGSGASSPLTSPSSPTPPSTS------ 509
+K + + + KR + +E S + +++ + S PL+ +S PP+ S
Sbjct: 732 EKTEEVGEGRVKRGPSQTTEPQSLVQLEDTSLTQLEATSLPLSGVTSELPPTISLPLLNN 791
Query: 510 -------GISALPPPPPPPPPPAAPLPPASTEAPAQLSSQA 543
I+ LP P PP PPP P PP P ++ +
Sbjct: 792 NLEPCSVTINPLPSPLPPTPPPPPPPPPPPPPPPLPVAKDS 832
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 52.8 bits (125), Expect = 9e-07
Identities = 40/133 (30%), Positives = 58/133 (43%), Gaps = 16/133 (12%)
Query: 416 KEALRIAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENS 475
K+ ++ AK+ +I E + ++ ++ A+ S E + S AL
Sbjct: 2298 KDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSET----VFDHPPSSVIALPMK 2353
Query: 476 EEHSAKYSNSNNSAG---------SGASSPLTSPSSPTP---PSTSGISALPPPPPPPPP 523
E+ S Y S + G SG+ S + P+ P P S+ ISA PPPPPPPPP
Sbjct: 2354 EQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP 2413
Query: 524 PAAPLPPASTEAP 536
P P PP P
Sbjct: 2414 PPPPPPPPPPPPP 2426
Score = 39.7 bits (91), Expect = 0.008
Identities = 20/51 (39%), Positives = 23/51 (45%)
Query: 493 ASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQLSSQA 543
A P P S PPS S PPP P P +P P ST+ P+Q A
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
Score = 38.9 bits (89), Expect = 0.013
Identities = 20/51 (39%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 486 NNSAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAP 536
++S A P P P PP PPPPPPPPP P P T P
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPP-------PPPPPPPPPLPPPTSPKPTILP 2439
Score = 37.7 bits (86), Expect = 0.029
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 9/135 (6%)
Query: 416 KEALRIAKECIEKRLIEEQKQIHQHRR-----LTRAQSHHGSEEERKKRKILARKKSKRS 470
+E+ ++ K+ E L EE+K+I R + R + E E+++R L R
Sbjct: 3775 RESAKLRKKQAE--LDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRD 3832
Query: 471 ALENSEEHSAKYSNSNNSAG--SGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPL 528
+ +SE S + + + G ++P T S PP T S L PP P
Sbjct: 3833 YMSDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSS 3892
Query: 529 PPASTEAPAQLSSQA 543
P T+AP + Q+
Sbjct: 3893 PALPTQAPTSYTQQS 3907
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 5/50 (10%)
Query: 492 GASSPLTSPSSPTPPSTSGISALPPPPPPP---PPPAAPLPPASTEAPAQ 538
G + P PS T P + PP PP PPA PL PA + PAQ
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA--KPPAQ 374
Score = 32.0 bits (71), Expect = 1.6
Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 3/51 (5%)
Query: 489 AGSGASSPLTSPSSPT-PPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQ 538
AG G +S + PT PPS A PPP P P P P S + P+Q
Sbjct: 454 AGPGKTS--AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Score = 30.0 bits (66), Expect = 6.1
Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 491 SGASSPLTSPSSPTPPSTSGISA-LPPPPPPPPPPAAPLPPAST-EAP 536
S AS+ +++ P P S SG A + P P PP + PP ST +AP
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP 987
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 52.8 bits (125), Expect = 9e-07
Identities = 40/133 (30%), Positives = 58/133 (43%), Gaps = 16/133 (12%)
Query: 416 KEALRIAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENS 475
K+ ++ AK+ +I E + ++ ++ A+ S E + S AL
Sbjct: 2298 KDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSET----VFDHPPSSVIALPMK 2353
Query: 476 EEHSAKYSNSNNSAG---------SGASSPLTSPSSPTP---PSTSGISALPPPPPPPPP 523
E+ S Y S + G SG+ S + P+ P P S+ ISA PPPPPPPPP
Sbjct: 2354 EQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP 2413
Query: 524 PAAPLPPASTEAP 536
P P PP P
Sbjct: 2414 PPPPPPPPPPPPP 2426
Score = 39.7 bits (91), Expect = 0.008
Identities = 20/51 (39%), Positives = 23/51 (45%)
Query: 493 ASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQLSSQA 543
A P P S PPS S PPP P P +P P ST+ P+Q A
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
Score = 38.9 bits (89), Expect = 0.013
Identities = 20/51 (39%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 486 NNSAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAP 536
++S A P P P PP PPPPPPPPP P P T P
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPP-------PPPPPPPPPLPPPTSPKPTILP 2439
Score = 37.7 bits (86), Expect = 0.029
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 9/135 (6%)
Query: 416 KEALRIAKECIEKRLIEEQKQIHQHRR-----LTRAQSHHGSEEERKKRKILARKKSKRS 470
+E+ ++ K+ E L EE+K+I R + R + E E+++R L R
Sbjct: 3775 RESAKLRKKQAE--LDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRD 3832
Query: 471 ALENSEEHSAKYSNSNNSAG--SGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPL 528
+ +SE S + + + G ++P T S PP T S L PP P
Sbjct: 3833 YMSDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSS 3892
Query: 529 PPASTEAPAQLSSQA 543
P T+AP + Q+
Sbjct: 3893 PALPTQAPTSYTQQS 3907
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 5/50 (10%)
Query: 492 GASSPLTSPSSPTPPSTSGISALPPPPPPP---PPPAAPLPPASTEAPAQ 538
G + P PS T P + PP PP PPA PL PA + PAQ
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA--KPPAQ 374
Score = 32.0 bits (71), Expect = 1.6
Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 3/51 (5%)
Query: 489 AGSGASSPLTSPSSPT-PPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQ 538
AG G +S + PT PPS A PPP P P P P S + P+Q
Sbjct: 454 AGPGKTS--AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Score = 30.0 bits (66), Expect = 6.1
Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 491 SGASSPLTSPSSPTPPSTSGISA-LPPPPPPPPPPAAPLPPAST-EAP 536
S AS+ +++ P P S SG A + P P PP + PP ST +AP
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP 987
>gi|24797143 sorting nexin 14 isoform b [Homo sapiens]
Length = 893
Score = 51.6 bits (122), Expect = 2e-06
Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
Query: 50 WQIVRRYSDFDLLNNSLQIAGLSLP---LPPKKLIGNMDREFIAERQKGLQNYLNVITTN 106
W + RRY +F +L + L + P LP K++IG + EF+ +++ Q YL + +
Sbjct: 558 WSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQH 617
Query: 107 HILSNCELVKKFLDPNNYSANYTEIALQQVSM 138
LSN +L+ FL PN + + L V++
Sbjct: 618 PELSNSQLLADFLSPNGGETQFLDKILPDVNL 649
>gi|24797145 sorting nexin 14 isoform a [Homo sapiens]
Length = 946
Score = 51.6 bits (122), Expect = 2e-06
Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
Query: 50 WQIVRRYSDFDLLNNSLQIAGLSLP---LPPKKLIGNMDREFIAERQKGLQNYLNVITTN 106
W + RRY +F +L + L + P LP K++IG + EF+ +++ Q YL + +
Sbjct: 611 WSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQH 670
Query: 107 HILSNCELVKKFLDPNNYSANYTEIALQQVSM 138
LSN +L+ FL PN + + L V++
Sbjct: 671 PELSNSQLLADFLSPNGGETQFLDKILPDVNL 702
>gi|154091028 sorting nexin 29 [Homo sapiens]
Length = 428
Score = 51.6 bits (122), Expect = 2e-06
Identities = 26/60 (43%), Positives = 37/60 (61%), Gaps = 3/60 (5%)
Query: 47 ENSWQIVRRYSDFDLLNNSLQIAGLSLP---LPPKKLIGNMDREFIAERQKGLQNYLNVI 103
++ W I RRY++F L++ LQ + PPKK IGN D +F+ ER+K LQNYL +
Sbjct: 301 DDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSV 360
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 51.2 bits (121), Expect = 3e-06
Identities = 65/235 (27%), Positives = 97/235 (41%), Gaps = 34/235 (14%)
Query: 345 MTYGRPPDSVPVDSFPPAPSMAVVAVLESTLSCEACKNGMPTISRLLQMPLFSDVLLTT- 403
MT +PP P S PPA S + VLE AC+ + + R P +D + T
Sbjct: 893 MTPTQPP---PPLSLPPARSES--EVLEEI--SRACETLVERVGRSATDP--ADPVDTAE 943
Query: 404 ---SEKPQFKIPTKLKE----ALRIAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSEEER 456
S + P + KE ++ C ++R E QK+ +HRR + E R
Sbjct: 944 PADSGTERLLPPAQAKEEAGGVAAVSGSC-KRRQKEHQKEHRRHRRACKDSVGRRPREGR 1002
Query: 457 KKRKILARKKSKRSALENSEEHSAKYSNSNNSAGS-GASSPLTSPSSPTPPSTSGISALP 515
K K K+ R L N + S + S G +S P++P PPS P
Sbjct: 1003 AKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSA------P 1056
Query: 516 PPPPPPPPPAAPLP--PASTEAPAQLSSQAVNGMSRGALLSSIQNFQKGTLRKAK 568
P P PP+A +P A EAP G+SR +L +++ +G ++ K
Sbjct: 1057 APSAQPTPPSASVPGKKAREEAPGP------PGVSRADML-KLRSLSEGPPKELK 1104
Score = 48.5 bits (114), Expect = 2e-05
Identities = 22/41 (53%), Positives = 24/41 (58%), Gaps = 5/41 (12%)
Query: 500 PSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQLS 540
P P PP LPPPPPPPPPP PLP +T P QL+
Sbjct: 242 PGLPLPPPP-----LPPPPPPPPPPPPPLPGLATSPPFQLT 277
Score = 39.7 bits (91), Expect = 0.008
Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 7/73 (9%)
Query: 483 SNSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPP------PPAAPLPPASTEAP 536
S+SN+++GS +SSP S P PP + S P P PP P PP PL A AP
Sbjct: 552 SSSNSNSGSHSSSPAGPVSFPPPPYLAR-SIDPLPRPPSPAQNPQDPPLVPLTLALPPAP 610
Query: 537 AQLSSQAVNGMSR 549
Q +G R
Sbjct: 611 PSSCHQNTSGSFR 623
Score = 36.2 bits (82), Expect = 0.085
Identities = 16/39 (41%), Positives = 20/39 (51%)
Query: 498 TSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAP 536
T+ ++ T +T PPP PPPPP A PP S P
Sbjct: 754 TTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQP 792
Score = 33.5 bits (75), Expect = 0.55
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 3/33 (9%)
Query: 500 PSSPTPPSTSGISALPPPPPPPPPPAAPLPPAS 532
P+ P PP ++ PPP P PPP P PAS
Sbjct: 773 PALPPPPP---LAKFPPPSQPQPPPPPPPSPAS 802
Score = 33.1 bits (74), Expect = 0.72
Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 11/71 (15%)
Query: 471 ALENSEEHSAKYSNSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPPP------PPPPP 524
ALE S H ++++S +P +P PP S PPPPP PPPPP
Sbjct: 429 ALEVSH-HGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSS----PPPPPCPRLLRPPPPP 483
Query: 525 AAPLPPASTEA 535
A PA A
Sbjct: 484 AWLKGPACRAA 494
Score = 32.3 bits (72), Expect = 1.2
Identities = 39/149 (26%), Positives = 52/149 (34%), Gaps = 26/149 (17%)
Query: 442 RLTRAQS---HHGSEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLT 498
RL +AQ H GS + R K + LE+ + AK A P+
Sbjct: 149 RLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAK--RGGPPVKRAAEPPVV 206
Query: 499 SPSSPT----PPSTSGIS--------------ALPPPPPPPPPPAAPLPPASTEAPAQLS 540
P P P G+S LPP P PPPP P PP P L
Sbjct: 207 QPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLP 266
Query: 541 SQAVN---GMSRGALLSSIQNFQKGTLRK 566
A + +++ L S++ G RK
Sbjct: 267 GLATSPPFQLTKPGLWSTLHGDAWGPERK 295
Score = 31.6 bits (70), Expect = 2.1
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 9/72 (12%)
Query: 466 KSKRSALENSEEHSAKYS-NSNNSAGSGASSPL-TSPSSPTPPSTSGISALPPPPPPPPP 523
KS S LE KY +A S PL T+ SP PPS G +ALPP P
Sbjct: 805 KSLASVLEGQ-----KYCYRGTGAAVSTRPGPLPTTQYSPGPPS--GATALPPTSAAPSA 857
Query: 524 PAAPLPPASTEA 535
+P P AS+ +
Sbjct: 858 QGSPQPSASSSS 869
Score = 30.8 bits (68), Expect = 3.6
Identities = 19/56 (33%), Positives = 23/56 (41%), Gaps = 5/56 (8%)
Query: 487 NSAGSGASSPLTSPSSPTP----PSTSGISALPPPPPPPPPPAAPLPPASTEAPAQ 538
+S S P SP P P T + PPP P P P+PP E PA+
Sbjct: 612 SSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQ-PVPPGVGELPAR 666
Score = 30.0 bits (66), Expect = 6.1
Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 7/44 (15%)
Query: 500 PSSPTPPSTSGISALPPPPPPPPPPAAPL------PPASTEAPA 537
P P +T +S LPP P PPPP P PPA + PA
Sbjct: 448 PFLGAPAATPHLS-LPPGPSSPPPPPCPRLLRPPPPPAWLKGPA 490
Score = 30.0 bits (66), Expect = 6.1
Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 11/60 (18%)
Query: 487 NSAGSGASSPLTSPSSPTPPSTSG----------ISALPPP-PPPPPPPAAPLPPASTEA 535
++A S SP S SS + STSG +P P P PPP LPPA +E+
Sbjct: 852 SAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSES 911
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 50.8 bits (120), Expect = 3e-06
Identities = 24/43 (55%), Positives = 28/43 (65%), Gaps = 1/43 (2%)
Query: 490 GSGASSPLTSPSSPTP-PSTSGISALPPPPPPPPPPAAPLPPA 531
G G +P +PSS + PS S S+ P PPPPPPPPA P PPA
Sbjct: 180 GDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPA 222
Score = 45.1 bits (105), Expect = 2e-04
Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 474 NSEEHSAKYSNSNNSAGSGASSPLTSPSSPTP-PSTSGISALPPPPPPPPPPAAPLPP 530
+S A++ G A P S +S +P PS S S PPPPPPPP P AP P
Sbjct: 166 SSRPTCARHLTLGTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAP 223
Score = 32.7 bits (73), Expect = 0.94
Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 3/40 (7%)
Query: 500 PSSPTPPSTSGISALPPPP---PPPPPPAAPLPPASTEAP 536
P+ P PS++ S P P P PPPP P P + AP
Sbjct: 184 PAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAP 223
Score = 31.6 bits (70), Expect = 2.1
Identities = 20/77 (25%), Positives = 33/77 (42%), Gaps = 8/77 (10%)
Query: 454 EERKKRKILARKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLTSPSSPTPPSTSG--- 510
EE R ++ + E EE + + + + A++P T+PS+ + SG
Sbjct: 1013 EEAGVRGGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAED 1072
Query: 511 -----ISALPPPPPPPP 522
+S LP PPP P
Sbjct: 1073 GPASRVSQLPTLPPPMP 1089
Score = 31.2 bits (69), Expect = 2.7
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 14/102 (13%)
Query: 446 AQSHHGSEEERK---KRKILARKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLTSPSS 502
A++ GS + +K K K A+K + K + S GSG L +
Sbjct: 888 AKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKA 947
Query: 503 PT-----------PPSTSGISALPPPPPPPPPPAAPLPPAST 533
+ S SG P PPP AAP PPA T
Sbjct: 948 DSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALT 989
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 50.4 bits (119), Expect = 4e-06
Identities = 29/62 (46%), Positives = 36/62 (58%), Gaps = 4/62 (6%)
Query: 490 GSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQLSSQAVNGMSR 549
G+ A++ L P P PP+T+ A PPPPPPPPPPA+ PAS PA A G +
Sbjct: 61 GAAAAALLLHPPPPPPPATA---APPPPPPPPPPPASAAAPAS-GPPAPPGLAAGPGPAG 116
Query: 550 GA 551
GA
Sbjct: 117 GA 118
Score = 31.6 bits (70), Expect = 2.1
Identities = 16/37 (43%), Positives = 18/37 (48%), Gaps = 10/37 (27%)
Query: 511 ISALPPPPPP----------PPPPAAPLPPASTEAPA 537
+S PPPPPP PPPPAA P + PA
Sbjct: 1 MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPA 37
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 50.4 bits (119), Expect = 4e-06
Identities = 41/156 (26%), Positives = 61/156 (39%), Gaps = 11/156 (7%)
Query: 385 PTISRLLQMPLFSDVLLTTSEKPQFKIPTKLK-EALRIAKECIEKRLIEEQKQIHQHRRL 443
P ++++ + VL + P FK +L + + C+ K +EE +Q
Sbjct: 443 PQYYKIIEECVSQIVLHCSGMDPDFKYRQRLDIDLTHLIDSCVNKAKVEESEQ------- 495
Query: 444 TRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLTSPSSP 503
A+ +EE R+ + KR E +E A+ A SS P P
Sbjct: 496 KAAEFSKKFDEEFTARQEAQAELQKRD--EKIKELEAEIQQLRTQA-QVLSSSSGIPGPP 552
Query: 504 TPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQL 539
P G+ PPPP PP P APLPP P +
Sbjct: 553 AAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMM 588
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 50.4 bits (119), Expect = 4e-06
Identities = 41/156 (26%), Positives = 61/156 (39%), Gaps = 11/156 (7%)
Query: 385 PTISRLLQMPLFSDVLLTTSEKPQFKIPTKLK-EALRIAKECIEKRLIEEQKQIHQHRRL 443
P ++++ + VL + P FK +L + + C+ K +EE +Q
Sbjct: 443 PQYYKIIEECVSQIVLHCSGMDPDFKYRQRLDIDLTHLIDSCVNKAKVEESEQ------- 495
Query: 444 TRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLTSPSSP 503
A+ +EE R+ + KR E +E A+ A SS P P
Sbjct: 496 KAAEFSKKFDEEFTARQEAQAELQKRD--EKIKELEAEIQQLRTQA-QVLSSSSGIPGPP 552
Query: 504 TPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQL 539
P G+ PPPP PP P APLPP P +
Sbjct: 553 AAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMM 588
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 50.4 bits (119), Expect = 4e-06
Identities = 36/117 (30%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Query: 22 AAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQIAGLSLP---LPPK 78
A + S+ + ++T YII+V G + W + RYSDF L+ L +A + LPPK
Sbjct: 19 ARVVGSELVDTYTVYIIQVTDG---SHEWTVKHRYSDFHDLHEKL-VAERKIDKNLLPPK 74
Query: 79 KLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFLDPNNYSANYTEIALQQ 135
K+IG R + +R+K L+ YL + ++ FL + Y N AL +
Sbjct: 75 KIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFYEINGITAALAE 131
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 50.1 bits (118), Expect = 6e-06
Identities = 26/62 (41%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 498 TSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQL--SSQAVNGMSRGALLSS 555
+ P P PP G PPPPPPPPPP++ PA P L + G RGALL
Sbjct: 378 SGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQ 437
Query: 556 IQ 557
I+
Sbjct: 438 IR 439
Score = 34.3 bits (77), Expect = 0.32
Identities = 15/30 (50%), Positives = 16/30 (53%)
Query: 501 SSPTPPSTSGISALPPPPPPPPPPAAPLPP 530
S P PP GI+ PP P PPPP PP
Sbjct: 339 SGPLPPVPLGIAPPPPTPRGPPPPGRGGPP 368
Score = 31.6 bits (70), Expect = 2.1
Identities = 25/101 (24%), Positives = 33/101 (32%), Gaps = 23/101 (22%)
Query: 459 RKILARKKSKRSALENSEEHSAKYSNSNNSAGSGA---SSPLTSPSSPTPPSTSGISALP 515
R + +R + L ++E Y + G A P P PP + G + LP
Sbjct: 268 RSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLP 327
Query: 516 PPP--------------------PPPPPPAAPLPPASTEAP 536
PP PPPP P P PP P
Sbjct: 328 RPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPP 368
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 50.1 bits (118), Expect = 6e-06
Identities = 29/67 (43%), Positives = 37/67 (55%), Gaps = 8/67 (11%)
Query: 496 PLTSPSSPTPPSTS----GISALPPPPPPPPPPAAPLPPA-STEAPAQLSSQAVNGMSRG 550
P ++PS P PP S G A PPPPPPPPPP P PP ++ Q+ + A N +
Sbjct: 351 PSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGN---KA 407
Query: 551 ALLSSIQ 557
ALL I+
Sbjct: 408 ALLDQIR 414
Score = 38.5 bits (88), Expect = 0.017
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 8/54 (14%)
Query: 496 PLTSPSSPTPPSTSGISALPPPPP--------PPPPPAAPLPPASTEAPAQLSS 541
P +P PP + +A PPPPP PPPPP PP P+ S
Sbjct: 303 PARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPS 356
Score = 37.4 bits (85), Expect = 0.038
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 12/77 (15%)
Query: 472 LENSEEHSAKYSNSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPPP-----PPPPPA- 525
L++ E Y + G A +P PP S PPPPP PPPPPA
Sbjct: 246 LKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPAR 305
Query: 526 ---APLPP---ASTEAP 536
AP PP A T AP
Sbjct: 306 GRGAPPPPPSRAPTAAP 322
Score = 37.0 bits (84), Expect = 0.050
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 3/87 (3%)
Query: 454 EERKKRKIL---ARKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLTSPSSPTPPSTSG 510
++R+ K++ K A++N A + G P S P PP G
Sbjct: 247 KDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARG 306
Query: 511 ISALPPPPPPPPPPAAPLPPASTEAPA 537
A PPPP P A P PP S + A
Sbjct: 307 RGAPPPPPSRAPTAAPPPPPPSRPSVA 333
Score = 35.0 bits (79), Expect = 0.19
Identities = 21/53 (39%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Query: 490 GSGASSPLTS---PSSPTPPSTSGISALPPPPPP---PPPPAAPLPPASTEAP 536
G GA P S ++P PP S S PPPPP PPP LP ++ P
Sbjct: 306 GRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGP 358
>gi|4885563 protein kinase C, epsilon [Homo sapiens]
Length = 737
Score = 49.7 bits (117), Expect = 7e-06
Identities = 62/269 (23%), Positives = 100/269 (37%), Gaps = 58/269 (21%)
Query: 183 LGPDKYLSDKDFQCLIK----LLPSCLHPYIYRVTFATANESSALLIRMFNEKGTLKDLI 238
L D L D D C + L + HPY+ ++ + + + G L I
Sbjct: 439 LKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQI 498
Query: 239 YKAKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNVMLDG 298
+++ K+ P+ + Y ++ L FLH G Y L N++LD
Sbjct: 499 QRSR-------KFDEPRS---------RFYAAEVTSALMFLHQHGVIYRDLKLDNILLDA 542
Query: 299 D-TCRLLDL------------ENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEM 345
+ C+L D + G P + Q ++ SVD G L+YEM
Sbjct: 543 EGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQ--ELEYGPSVDWWALGVLMYEM 600
Query: 346 TYGRPP----------DSVPVDS--FPPAPSMAVVAVLES--------TLSCEACKNGMP 385
G+PP +S+ D +P S V++L++ L C A +NG
Sbjct: 601 MAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGED 660
Query: 386 TISRLLQMPLFSDVLLTTSEKPQFKIPTK 414
I Q P F ++ E+ + K P K
Sbjct: 661 AIK---QHPFFKEIDWVLLEQKKIKPPFK 686
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
sapiens]
Length = 1584
Score = 49.7 bits (117), Expect = 7e-06
Identities = 22/44 (50%), Positives = 22/44 (50%)
Query: 494 SSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPA 537
S P P S PP PPPPPPPPPP PLPP PA
Sbjct: 1392 SPPSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNLEPA 1435
Score = 43.9 bits (102), Expect = 4e-04
Identities = 23/52 (44%), Positives = 23/52 (44%)
Query: 488 SAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQL 539
S AS P SP S PPS A P PPPPPPP P P P L
Sbjct: 1381 STAPEASLPARSPPSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNL 1432
Score = 31.6 bits (70), Expect = 2.1
Identities = 18/53 (33%), Positives = 22/53 (41%), Gaps = 3/53 (5%)
Query: 488 SAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAA---PLPPASTEAPA 537
S G + P P P PP LPPPP P P + P PA+ P+
Sbjct: 1400 SGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNLEPAPPSLGDPGEPAAHPGPS 1452
>gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [Homo
sapiens]
Length = 464
Score = 49.7 bits (117), Expect = 7e-06
Identities = 33/106 (31%), Positives = 56/106 (52%), Gaps = 6/106 (5%)
Query: 17 TVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSL--QIAGLSLP 74
+V + ++ E + + T Y + V G S W + RRY++FD L N+L Q ++L
Sbjct: 15 SVSIPSSDEHREKKKRFTVYKVLVSVGRS---EWFVFRRYAEFDKLYNTLKKQFPAMALK 71
Query: 75 LPPKKLIG-NMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFL 119
+P K++ G N D +FI +R+ GL ++ + L N V+ FL
Sbjct: 72 IPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFL 117
>gi|23943858 sorting nexin 8 [Homo sapiens]
Length = 465
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/112 (31%), Positives = 58/112 (51%), Gaps = 9/112 (8%)
Query: 11 KVLLDDTVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSL--QI 68
++L DTV + E H EY + QR S + RRY+DF + L +
Sbjct: 70 ELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKS-----SVYRRYNDFVVFQEMLLHKF 124
Query: 69 AGLSLP-LPPKKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFL 119
+P LPPK+++G DREFI R++ L+ ++N++ + + S ++K FL
Sbjct: 125 PYRMVPALPPKRMLG-ADREFIEARRRALKRFVNLVARHPLFSEDVVLKLFL 175
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 49.3 bits (116), Expect = 1e-05
Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 6/76 (7%)
Query: 28 QSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQIAGL---SLPLPPKKLIGNM 84
Q +H E+ +++ ++ +W + RRYS F ++ +L++ +L PPKKL GN
Sbjct: 1196 QGKDAHFEFEVKIT---VLDETWTVFRRYSRFREMHKTLKLKYAELAALEFPPKKLFGNK 1252
Query: 85 DREFIAERQKGLQNYL 100
D IAER+ L+ YL
Sbjct: 1253 DERVIAERRSHLEKYL 1268
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/90 (35%), Positives = 40/90 (44%), Gaps = 2/90 (2%)
Query: 476 EEHSAKYSNSNNSAGSGASSPLT-SPSSPTPPSTSGISA-LPPPPPPPPPPAAPLPPAST 533
EE S S N + PL+ P TP + S S LPPPPPPPPPP P PP
Sbjct: 588 EESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP 647
Query: 534 EAPAQLSSQAVNGMSRGALLSSIQNFQKGT 563
P+Q + A + S+I Q +
Sbjct: 648 PLPSQSAPSAGSAAPMFVKYSTITRLQNAS 677
Score = 46.2 bits (108), Expect = 8e-05
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 9/90 (10%)
Query: 493 ASSPLTSPSSPTPPSTSGISALPPPP------PPPPPPAAPLPPASTEAPAQLSSQAVNG 546
+S P+ SP P PP S + PPPP PPPPPP A P + +P + +S+
Sbjct: 907 SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKT--- 963
Query: 547 MSRGALLSSIQNFQKGTLRKAKTCDHSAPK 576
S G + +++ + +H PK
Sbjct: 964 SSPGGKKPPPTPQRNSSIKSSSGAEHPEPK 993
Score = 37.4 bits (85), Expect = 0.038
Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 5/41 (12%)
Query: 501 SSPTPP----STSGISALPPP-PPPPPPPAAPLPPASTEAP 536
S+P PP I+ + PP PPPPPP APLPP + P
Sbjct: 741 SAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKP 781
Score = 35.0 bits (79), Expect = 0.19
Identities = 26/61 (42%), Positives = 26/61 (42%), Gaps = 19/61 (31%)
Query: 481 KYSN----SNNSAGSGASSPLTSPSSPTPPSTSGISALP----------PPPPPPPPPAA 526
KYS N S SGA L P PTPP S P PPPPPPPPP
Sbjct: 666 KYSTITRLQNASQHSGA---LFKP--PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 527 P 527
P
Sbjct: 721 P 721
Score = 35.0 bits (79), Expect = 0.19
Identities = 20/48 (41%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 497 LTSPSSPTPPSTSGISALPPPPPPPPPPAAPLP-PASTEAPAQLSSQA 543
+T + PTPP I A P PP PP P +P P ST+ A + +QA
Sbjct: 755 ITQVAPPTPPPPPPIPA-PLPPQAPPKPLVTIPAPTSTKTVAPVVTQA 801
Score = 33.1 bits (74), Expect = 0.72
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 5/54 (9%)
Query: 491 SGASSPLTSPSSPTPPSTSGISALPPPPPPPPP-PAAPLPPASTEAPAQLSSQA 543
S + P SP SP P I++ PPPP PP + PL P PA ++ Q+
Sbjct: 845 SFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP----VPANVAPQS 894
Score = 32.7 bits (73), Expect = 0.94
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 14/72 (19%)
Query: 464 RKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLTSPSSP---------TPPSTSGISA- 513
+K SK S+ + NS+ + SGA P P P TPP+ SG +
Sbjct: 958 KKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHP--EPKRPSVDSLVSKFTPPAESGSPSK 1015
Query: 514 --LPPPPPPPPP 523
LPPP PP P
Sbjct: 1016 ETLPPPAAPPKP 1027
Score = 31.6 bits (70), Expect = 2.1
Identities = 18/38 (47%), Positives = 19/38 (50%), Gaps = 8/38 (21%)
Query: 503 PTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQLS 540
P+PPS S PPPPP PLPP E PA S
Sbjct: 1065 PSPPSDSDF------PPPPPETELPLPP--IEIPAVFS 1094
Score = 30.4 bits (67), Expect = 4.6
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 7/42 (16%)
Query: 503 PTPPSTSGIS-----ALPPPPPPPPPPAAPLP--PASTEAPA 537
P P ST ++ A PP P PP PPA P PAS P+
Sbjct: 786 PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827
Score = 30.0 bits (66), Expect = 6.1
Identities = 13/33 (39%), Positives = 17/33 (51%), Gaps = 4/33 (12%)
Query: 499 SPSSPTPPSTSG----ISALPPPPPPPPPPAAP 527
+P+ P PP+ S +PP PP PP P P
Sbjct: 805 TPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP 837
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 48.1 bits (113), Expect = 2e-05
Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 6/60 (10%)
Query: 490 GSGASSPLTSPSSPTPPSTSGISAL------PPPPPPPPPPAAPLPPASTEAPAQLSSQA 543
G+ +S PL P P PPS+ + PP PPPPPPP P PP P L A
Sbjct: 519 GAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPA 578
Score = 44.7 bits (104), Expect = 2e-04
Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 485 SNNSAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPAST 533
S+++ + + P+T P P PP PPPPPPPPPP P P A T
Sbjct: 536 SSDTPETVQNGPVTPPMPPPPPPPP---PPPPPPPPPPPPPLPGPAAET 581
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/69 (33%), Positives = 27/69 (39%), Gaps = 16/69 (23%)
Query: 485 SNNSAGSGASSPLTSPSSPTPPS----------------TSGISALPPPPPPPPPPAAPL 528
+ NS G + + P P PP T + PPPPPPPPPP P
Sbjct: 510 AGNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPP 569
Query: 529 PPASTEAPA 537
PP PA
Sbjct: 570 PPPPLPGPA 578
Score = 37.0 bits (84), Expect = 0.050
Identities = 31/142 (21%), Positives = 55/142 (38%), Gaps = 2/142 (1%)
Query: 397 SDVLLTTSEKPQFKIPTKLKEALRIAKECIEKRLI--EEQKQIHQHRRLTRAQSHHGSEE 454
S+ L T + KI K+ ++ KE R I + Q+H R++ + + +
Sbjct: 406 SEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQ 465
Query: 455 ERKKRKILARKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLTSPSSPTPPSTSGISAL 514
++KI +K ++ + S S + + +S P + S
Sbjct: 466 STLEKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGP 525
Query: 515 PPPPPPPPPPAAPLPPASTEAP 536
PPPPPP PP++ P P
Sbjct: 526 LPPPPPPLPPSSDTPETVQNGP 547
>gi|38492356 DNA-directed DNA polymerase delta 3 [Homo sapiens]
Length = 466
Score = 47.8 bits (112), Expect = 3e-05
Identities = 40/154 (25%), Positives = 64/154 (41%), Gaps = 16/154 (10%)
Query: 408 QFKIPTKLKEALRIAKECIEKRLIEEQKQIHQHRRLTRAQSHHGSEEERKKRKILAR--K 465
+FK+ ++A++ E++++E+ +L S ++ + K+L + K
Sbjct: 246 KFKVNLDSEQAVK------EEKIVEQPTVSVTEPKLATPAGLKKSSKKAEPVKVLQKEKK 299
Query: 466 KSKRSALENSE----EHSAKYSNSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPPPPP 521
+ KR AL + E E+ K S +S P SP P PPPPP
Sbjct: 300 RGKRVALSDDETKETENMRKKRRRIKLPESDSSEDEVFPDSPGAYEAES----PSPPPPP 355
Query: 522 PPPAAPLPPASTEAPAQLSSQAVNGMSRGALLSS 555
PP P+P E P+ SS N R +L S
Sbjct: 356 SPPLEPVPKTEPEPPSVKSSSGENKRKRKRVLKS 389
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 47.8 bits (112), Expect = 3e-05
Identities = 35/107 (32%), Positives = 47/107 (43%), Gaps = 20/107 (18%)
Query: 439 QHRRLTRAQSHHGSEEERKKRKILARKKSKRSALEN----SEEHSAKYSNSNNSAGSGAS 494
Q ++L + EEE+ K +K +R+ E +E+ AK
Sbjct: 357 QEQKLDDEEEEKKEEEEKDKE---GEEKEERAVAEEMMPAAEKEEAKLP----------P 403
Query: 495 SPLTSPSSPTPPSTSGISALPPPP--PPPPPPAAPLP-PASTEAPAQ 538
PLT P+ PP S PPPP PPPPPP +P P P+ PAQ
Sbjct: 404 PPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQ 450
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/61 (42%), Positives = 27/61 (44%), Gaps = 23/61 (37%)
Query: 500 PSSPTPPST--------------------SGISALPPPPPPPPPPAAPLPPASTEAPAQL 539
P +PTPPST S LPPPPP PPPP AP PP APA
Sbjct: 584 PRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPP---PAPATS 640
Query: 540 S 540
S
Sbjct: 641 S 641
Score = 38.1 bits (87), Expect = 0.022
Identities = 22/76 (28%), Positives = 29/76 (38%), Gaps = 4/76 (5%)
Query: 466 KSKRSALENSEEHSAKYSNSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPP--PPPPP 523
K + L++ EE + + + P + LPPPP PP P
Sbjct: 355 KKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEE--AKLPPPPLTPPAPS 412
Query: 524 PAAPLPPASTEAPAQL 539
P PLPP ST P L
Sbjct: 413 PPPPLPPPSTSPPPPL 428
Score = 36.2 bits (82), Expect = 0.085
Identities = 25/63 (39%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 493 ASSPL-TSPSSPTPPSTSGISALPPPPP--PPPPPAAPLPPASTEAPAQLSSQAVNGMSR 549
AS PL TSP PP TS ++AL P PP PA PP P + V+G+S
Sbjct: 1929 ASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSA 1988
Query: 550 GAL 552
L
Sbjct: 1989 ADL 1991
Score = 34.7 bits (78), Expect = 0.25
Identities = 29/113 (25%), Positives = 45/113 (39%), Gaps = 5/113 (4%)
Query: 432 EEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSAGS 491
EE Q RR+ Q GS +K+ + L ++ ++ E ++ + +
Sbjct: 333 EESWQDVPQRRVGSGQG--GSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEM 390
Query: 492 GASSPLTSPSSPTPPSTSGISALPPPPPPP---PPPAAPLPPASTEAPAQLSS 541
++ P PP T + PPP PPP PPP PP +P L S
Sbjct: 391 MPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPS 443
Score = 33.9 bits (76), Expect = 0.42
Identities = 25/104 (24%), Positives = 39/104 (37%), Gaps = 3/104 (2%)
Query: 473 ENSEEHSAKYSNSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPAS 532
E+ EE + + + A S S L S P P PPP AP PP
Sbjct: 117 ESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPP-- 174
Query: 533 TEAPAQLSSQAVNGMSRGALLSSIQNFQKGTLRKAKTCDHSAPK 576
+ PA+ + AL ++ Q +++ C+ S P+
Sbjct: 175 -KTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPR 217
Score = 33.1 bits (74), Expect = 0.72
Identities = 23/72 (31%), Positives = 27/72 (37%), Gaps = 16/72 (22%)
Query: 489 AGSGASSPLTSPSSPTPPSTSGIS----ALPPPP------------PPPPPPAAPLPPAS 532
AG G P P PP+ S + LPP P P PPPP PL
Sbjct: 2205 AGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVL 2264
Query: 533 TEAPAQLSSQAV 544
+ PA QA+
Sbjct: 2265 SSGPASPPRQAI 2276
Score = 32.7 bits (73), Expect = 0.94
Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 6/66 (9%)
Query: 482 YSNSNNSAGSGASSPLTSPSSPTPPS----TSGISALPPPP--PPPPPPAAPLPPASTEA 535
YS S G + PL SP SP+ + T G P PP P P AP PP S A
Sbjct: 1870 YSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWA 1929
Query: 536 PAQLSS 541
L +
Sbjct: 1930 SPPLKT 1935
Score = 32.3 bits (72), Expect = 1.2
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 9/43 (20%)
Query: 497 LTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQL 539
LT P PP+ PPPPP P PP P P S+ P L
Sbjct: 614 LTRELPPPPPA-------PPPPPAPSPP--PAPATSSRRPLLL 647
Score = 31.2 bits (69), Expect = 2.7
Identities = 24/107 (22%), Positives = 41/107 (38%), Gaps = 11/107 (10%)
Query: 432 EEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSAGS 491
++++++ + + E E K+ + +A + + E ++ + S
Sbjct: 356 KQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP 415
Query: 492 GASSPLTSPSSPT-PPSTSGISALP---PPPPP-------PPPPAAP 527
P TSP P PP +S P PPPPP PPP P
Sbjct: 416 PLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVP 462
Score = 31.2 bits (69), Expect = 2.7
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 494 SSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLP 529
S L P + +PP + +P PP P PP+ P+P
Sbjct: 560 SPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVP 595
Score = 30.8 bits (68), Expect = 3.6
Identities = 29/108 (26%), Positives = 40/108 (37%), Gaps = 27/108 (25%)
Query: 493 ASSPLTSPSSPTPPSTSGI---------------------SALPPPPPPPPPPAAPLPPA 531
A P +PS P P+TS S L PPP P P PP
Sbjct: 624 APPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPP 683
Query: 532 STEAPAQLSSQAVNGMSRGALLSSIQNFQK--GTLRKAKTCDHSAPKI 577
+ ++PA+ +AV + S+ F T KA+ H AP +
Sbjct: 684 ADDSPAEPEPRAVGRTNH----LSLPRFAPVVTTPVKAEVSPHGAPAL 727
Score = 30.0 bits (66), Expect = 6.1
Identities = 15/32 (46%), Positives = 16/32 (50%), Gaps = 1/32 (3%)
Query: 505 PPSTSGISALPPPPPPPPPPAAPLPPASTEAP 536
PP T+ P P P PP AP PP ST P
Sbjct: 565 PPITTSPPVPQEPAPVPSPPRAPTPP-STPVP 595
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 47.8 bits (112), Expect = 3e-05
Identities = 27/67 (40%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Query: 500 PSSPTPPSTSGISALPPP--PPPPPPPAAPLPPASTEAPAQLSS--QAVNGMSRGALLSS 555
P P PP PPP PPPPPPPA+PLPP P SS + G+S L
Sbjct: 331 PPRPLPPRPPAAQPRPPPSPPPPPPPPASPLPPPPPPPPPTPSSTTKLPQGLSFAKRLQQ 390
Query: 556 IQNFQKG 562
+ KG
Sbjct: 391 LIEVLKG 397
Score = 40.8 bits (94), Expect = 0.003
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 5/48 (10%)
Query: 493 ASSPLTSPSSPTPPSTSGISALPPPPPPPPPPAAPLPPASTEAPAQLS 540
A+ P PS P PP PPPPPPPP P+ ++T+ P LS
Sbjct: 341 AAQPRPPPSPPPPPPPPASPLPPPPPPPPPTPS-----STTKLPQGLS 383
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,432,453
Number of Sequences: 37866
Number of extensions: 1416621
Number of successful extensions: 53368
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1113
Number of HSP's successfully gapped in prelim test: 1023
Number of HSP's that attempted gapping in prelim test: 21532
Number of HSP's gapped (non-prelim): 18688
length of query: 578
length of database: 18,247,518
effective HSP length: 108
effective length of query: 470
effective length of database: 14,157,990
effective search space: 6654255300
effective search space used: 6654255300
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.