Search of human proteins with 31542729

Search of human proteins with 31542729

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo
sapiens]
         (779 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi...  1571   0.0  
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po...   893   0.0  
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]    520   e-147
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi...   496   e-140
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]   477   e-134
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi...   452   e-127
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi...   439   e-123
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi...   403   e-112
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi...   313   4e-85
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1...   281   2e-75
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom...   275   1e-73
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2...   270   5e-72
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo...   260   4e-69
gi|166851804 tudor domain containing 9 [Homo sapiens]                 246   8e-65
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ...   238   1e-62
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ...   238   1e-62
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi...   228   2e-59
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi...   228   2e-59
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi...   171   2e-42
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ...   152   9e-37
gi|38505213 YTH domain containing 2 [Homo sapiens]                    150   6e-36
gi|19923796 NMD3 homolog [Homo sapiens]                                35   0.35 
gi|66472922 muscle-related coiled-coil protein [Homo sapiens]          33   0.78 
gi|110349719 titin isoform N2-A [Homo sapiens]                         32   3.0  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      32   3.0  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      32   3.0  
gi|110349715 titin isoform N2-B [Homo sapiens]                         32   3.0  
gi|13129006 nucleolar protein GU2 [Homo sapiens]                       32   3.0  
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]           31   5.0  
gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]             31   5.0  

>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo
           sapiens]
          Length = 779

 Score = 1571 bits (4069), Expect = 0.0
 Identities = 779/779 (100%), Positives = 779/779 (100%)

Query: 1   MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 60
           MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK
Sbjct: 1   MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 60

Query: 61  KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE 120
           KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE
Sbjct: 61  KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE 120

Query: 121 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 180
           EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL
Sbjct: 121 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 180

Query: 181 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 240
           TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK
Sbjct: 181 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 240

Query: 241 FCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 300
           FCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD
Sbjct: 241 FCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 300

Query: 301 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 360
           YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV
Sbjct: 301 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 360

Query: 361 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 420
           VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD
Sbjct: 361 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 420

Query: 421 HVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVT 480
           HVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVT
Sbjct: 421 HVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVT 480

Query: 481 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH 540
           RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH
Sbjct: 481 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH 540

Query: 541 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL 600
           RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL
Sbjct: 541 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL 600

Query: 601 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTVDGRGSPVHIHPSSALHE 660
           KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTVDGRGSPVHIHPSSALHE
Sbjct: 601 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTVDGRGSPVHIHPSSALHE 660

Query: 661 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR 720
           QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR
Sbjct: 661 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR 720

Query: 721 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG 779
           RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG
Sbjct: 721 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG 779


>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
           polypeptide 40 [Homo sapiens]
          Length = 452

 Score =  893 bits (2308), Expect = 0.0
 Identities = 446/449 (99%), Positives = 448/449 (99%)

Query: 1   MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 60
           MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK
Sbjct: 1   MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 60

Query: 61  KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE 120
           KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE
Sbjct: 61  KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE 120

Query: 121 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 180
           EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL
Sbjct: 121 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 180

Query: 181 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 240
           TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK
Sbjct: 181 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 240

Query: 241 FCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 300
           FCNLIGPRDRENTAYIQAIV+VTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD
Sbjct: 241 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 300

Query: 301 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 360
           YDYDVQDT LDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV
Sbjct: 301 YDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 360

Query: 361 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 420
           VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD
Sbjct: 361 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 420

Query: 421 HVIPEIKRTSLTSVVLTLKCLAIHDVIRF 449
           HVIPEIKRTSLTSVVLTLKCLAIHDVIR+
Sbjct: 421 HVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449


>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
          Length = 1220

 Score =  520 bits (1338), Expect = e-147
 Identities = 286/666 (42%), Positives = 420/666 (63%), Gaps = 33/666 (4%)

Query: 52   TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAA 111
            + PI K +++++QAV DN  LIV G TGSGKTTQ+ +YL EAG++  G IG TQPR+VAA
Sbjct: 564  SLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAA 623

Query: 112  ISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVII 171
            +SVA+RV+EE  C LG +VGY +RF+DC+S ET IKYMTDG LL+  L DP+LT++++I+
Sbjct: 624  MSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIM 683

Query: 172  LDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIP 231
            LDEAHERT+ TD+LFGLLKK  Q     +++ +K++V SAT++  K S +F   PIF IP
Sbjct: 684  LDEAHERTIHTDVLFGLLKKTVQ-----KRQDMKLIVTSATLDAVKFSQYFYEAPIFTIP 738

Query: 232  GRLYPVREKFCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCEL 291
            GR YPV   +           T Y+ A +   M IHL E  GDILVFLTGQ EI+ +CE+
Sbjct: 739  GRTYPVEILYTK------EPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEI 792

Query: 292  LFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATS 351
            L++  +S+  D       +  L+ILP Y ++ ++ Q RIF P PPG RK VI+TNI+ TS
Sbjct: 793  LYERMKSLGPD-------VPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETS 845

Query: 352  LTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSK 411
            LTIDGI YVVD GFVKQ  +N + G+D L V PIS+++A QR+GRAGRT  GKC+R+Y++
Sbjct: 846  LTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTE 905

Query: 412  DFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCD 471
              +   M    +PEI+RT+L S VL+LK + I+D++ F ++D P    ++ A++QLY   
Sbjct: 906  RAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLG 965

Query: 472  AIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPE 531
            A+D  G +TRLG  M EFPL P L   +I +  L C + +L I +MLSV+NVF RP D  
Sbjct: 966  ALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDK- 1024

Query: 532  YQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEA 591
             Q  A+Q+  +     G   D  TL  ++   K++     WC +++I  R L  A  +  
Sbjct: 1025 -QALADQKKAKFHQTEG---DHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRK 1080

Query: 592  QLRELIRKLKQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTVDGRGSPVH 651
            Q+  ++ + K           G     +++ +C+G+F+N A++     + T+  +   V+
Sbjct: 1081 QMLGIMDRHKLD-----VVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQ-QVVY 1134

Query: 652  IHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVA 711
            IHPSSAL  ++   EW+++HE+++TTK Y R V  I   W+ +  P    F   D + ++
Sbjct: 1135 IHPSSALFNRQP--EWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAF--FKVSDPTKLS 1190

Query: 712  RREVRE 717
            +++ ++
Sbjct: 1191 KQKKQQ 1196


>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
          Length = 1227

 Score =  496 bits (1278), Expect = e-140
 Identities = 268/699 (38%), Positives = 429/699 (61%), Gaps = 37/699 (5%)

Query: 54   PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAIS 113
            PI   +++++  +RDNS +IV G TGSGKTTQL +YL+E G++ +GMIG TQPR+VAA+S
Sbjct: 533  PIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMS 592

Query: 114  VAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILD 173
            VA+RV+EEM   LG +VGY +RF+DC+S+ T IKYMTDG LL+  L + +L  +S II+D
Sbjct: 593  VAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMD 652

Query: 174  EAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGR 233
            EAHER+L TD+LFGLL+++       R+  LK++V SATM+  K +AFFGN PIF IPGR
Sbjct: 653  EAHERSLNTDVLFGLLREVVA-----RRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGR 707

Query: 234  LYPVREKFCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLF 293
             +PV   F     P++     Y++A V+ ++ +HL+   GDIL+F+ GQ +IE + + + 
Sbjct: 708  TFPVDILFSKT--PQED----YVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIV 761

Query: 294  QMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLT 353
            +  E ++            L +LP Y  + +D Q +IF   P G+RKC+++TNI+ TSLT
Sbjct: 762  EHLEELE--------NAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLT 813

Query: 354  IDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDF 413
            +DGI +V+D G+ K    NPR+G+D L++ PIS++ A QRSGRAGRT  G+CFR+Y++  
Sbjct: 814  VDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSA 873

Query: 414  WNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAI 473
            +   +    +PEI+RT+L +VVL LK L + D+++F ++DPP E  +L ++ QL+   A+
Sbjct: 874  YKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLWILGAL 933

Query: 474  DRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQ 533
            D +G +T  G  MVEFPL P L+  +I +  + C   +L I +MLSV  +F RP   E  
Sbjct: 934  DNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGRE-- 991

Query: 534  KEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQL 593
            +E++Q   + A      +D  T   ++ Q K++     WC  H+IH + +     V AQL
Sbjct: 992  EESDQIREKFAVPE---SDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQL 1048

Query: 594  RELIRKLKQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTVDGRGSPVHIH 653
            ++++  ++Q+         G   +++R+C+CA YF   A+      +  +   G P H+H
Sbjct: 1049 KDIM--VQQRMSLAS---CGTDWDIVRKCICAAYFHQAAKLKGIGEYVNI-RTGMPCHLH 1102

Query: 654  PSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARR 713
            P+S+L       ++I++HE+++TTK Y + V  +  EW+ +L P  +       S     
Sbjct: 1103 PTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVKQAGKS----- 1157

Query: 714  EVREDARRRWTNKENVKQLKDGISKDVLKKMQRRNDDKS 752
              R++ RRR   + +  + +  ++++ L+  ++  + +S
Sbjct: 1158 --RQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRS 1194


>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
          Length = 1041

 Score =  477 bits (1227), Expect = e-134
 Identities = 276/666 (41%), Positives = 408/666 (61%), Gaps = 53/666 (7%)

Query: 51   PTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM-IGVTQPRKV 109
            P FP    R++++ A+ ++  LI+ G TGSGKTTQ+P+YL+E G++  GM I  TQPR+V
Sbjct: 400  PVFPF---REELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRV 456

Query: 110  AAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSV 169
            AA+SVA RVA EM   LG++VGY +RF+DC+S+ T ++YMTDG LL+  L +P+L  +SV
Sbjct: 457  AAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSV 516

Query: 170  IILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFD 229
            +++DEAHERTL TDILFGL+K + + +       LKV+V SATM+ A+ S FF + P+F 
Sbjct: 517  VMVDEAHERTLHTDILFGLIKDVARFRP-----ELKVLVASATMDTARFSTFFDDAPVFR 571

Query: 230  IPGRLYPVREKFCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSC 289
            IPGR +PV + F       D     Y++A V   + IH+ +  GDILVFLTGQ EIE +C
Sbjct: 572  IPGRRFPV-DIFYTKAPEAD-----YLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAAC 625

Query: 290  ELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISA 349
            E+L      +        + +  LL+LP Y ++ +D Q RIF P PPG RK V++TNI+ 
Sbjct: 626  EMLQDPCRRLG-------SKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAE 678

Query: 350  TSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIY 409
            TS TI+GI YV+D GF KQ ++NPR G++ L V P SK+ A QR+GRAGR ++GKCFR+Y
Sbjct: 679  TSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLY 738

Query: 410  SKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQ 469
            +   +   + +  +PEI+RTSL +VVL LK L IHD++ F +LDPP    +L  L+QLY 
Sbjct: 739  TAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYA 798

Query: 470  CDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVEN-VFIRPV 528
              A++  G +T  G  M E P+ P L+  ++ +    C + +L +AAMLSV N +F RP 
Sbjct: 799  LGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPK 858

Query: 529  DPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFR 588
            D     +  + +  L    GG  D   L  ++ Q   SG  + WC ++++ +R +  A  
Sbjct: 859  DKVVHADNARVNFFL---PGG--DHLVLLNVYTQWAESGYSSQWCCENFVQFRSMRRARD 913

Query: 589  VEAQLRELIRKLKQ-----QSDFPKETFEGPKHEVLRRCLCAGYFKNVAR--RSVGRTFC 641
            V  QL  L+ +++      Q D+ +          +R+ + AGYF + AR  RS  RT  
Sbjct: 914  VREQLEGLLERVEVGLSSCQGDYIR----------VRKAITAGYFYHTARLTRSGYRTV- 962

Query: 642  TVDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHE 701
                +   V IHP+S+L EQ+ +  W+++HE+++TTK + R V  I   W+ ++ P  H 
Sbjct: 963  ---KQQQTVFIHPNSSLFEQQPR--WLLYHELVLTTKEFMRQVLEIESSWLLEVAP--HY 1015

Query: 702  FNAHDL 707
            + A +L
Sbjct: 1016 YKAKEL 1021


>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
           sapiens]
          Length = 795

 Score =  452 bits (1164), Expect = e-127
 Identities = 270/651 (41%), Positives = 390/651 (59%), Gaps = 45/651 (6%)

Query: 66  VRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM---IGVTQPRKVAAISVAQRVAEEM 122
           VR  SF++V G TGSGKTTQ+P++  E   S  G    +  TQPR+VAA+SVAQRVA+EM
Sbjct: 151 VRHQSFVLV-GETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEM 209

Query: 123 KCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTT 182
              LG +VGY +RF+DCSS +T +KYMTDG LL+  + DP L ++ VIILDEAHERTL T
Sbjct: 210 DVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLAT 269

Query: 183 DILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFC 242
           DIL G+LK++ +++S      LKV+VMSAT++  K   +F NCP+  IPGR +PV E F 
Sbjct: 270 DILMGVLKEVVRQRSD-----LKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPV-EIFY 323

Query: 243 NLIGPRDRENTAYIQAIVEVTMDIHL-NEMAGDILVFLTGQFEIEKSCELLFQMAESVDY 301
                RD     Y++A +   + IH+  E  GD+L+FLTGQ EI+++C+ + +  +  D 
Sbjct: 324 TPEPERD-----YLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVD--DL 376

Query: 302 DYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGI------RKCVISTNISATSLTID 355
             +V D     + I+P Y ++   QQ+RIF PPPP        RK V+STNI+ TSLTID
Sbjct: 377 GPEVGD-----IKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTID 431

Query: 356 GIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWN 415
           G+ +V+D GF KQ  +NPR+ ++ L V  ISK+ A QR+GRAGRT  GKCFR+Y++  + 
Sbjct: 432 GVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYK 491

Query: 416 QCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDR 475
             M D+  PEI R++L SVVL LK L I D++ F ++DPP    ++ AL+ L    A++ 
Sbjct: 492 TEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALND 551

Query: 476 SGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKE 535
            G +T LG  M EFPL P L   VI +   +C + +L I AMLSV   F+RP   E +K 
Sbjct: 552 DGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPT--EAKKA 609

Query: 536 AEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRE 595
           A++     A   G   D  TL  ++   K +     WC  ++I++R L SA  V  QL  
Sbjct: 610 ADEAKMRFAHIDG---DHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSR 666

Query: 596 LIRKL---KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTVDGRGSPVHI 652
           ++ +    ++ +DF    +    +  +R+ L  GYF  VA       + TV      V +
Sbjct: 667 IMDRFNLPRRSTDFTSRDY----YINIRKALVTGYFMQVAHLERTGHYLTVKD-NQVVQL 721

Query: 653 HPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFN 703
           HPS+ L   + K EW++++E ++TTK Y R    I+ EW+  + P+ ++ +
Sbjct: 722 HPSTVL---DHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMS 769


>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
           sapiens]
          Length = 703

 Score =  439 bits (1128), Expect = e-123
 Identities = 256/709 (36%), Positives = 414/709 (58%), Gaps = 58/709 (8%)

Query: 38  EEKGCTSQEGGTTPTF---------------PIQKQRKKIIQAVRDNSFLIVTGNTGSGK 82
           EE+   ++  GTT  +               P+ K R  I+  + +   +++ G TG GK
Sbjct: 24  EERQSLAENSGTTVVYNPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGK 83

Query: 83  TTQLPKYLYEAGFSQHG-MIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSS 141
           +TQ+P+YL EAG++  G ++GVTQPR+VAA++VA RVAEE    LG +VGY +RFDDC+ 
Sbjct: 84  STQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTD 143

Query: 142 K-ETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNR 200
           +  T IK++TDG L++ ++ DP LTK+SVI+LDEAHERTL TDI  GLLKK+ +++    
Sbjct: 144 QLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGD-- 201

Query: 201 KEHLKVVVMSATMELAKLSAFFGN----------CPIFDIPGRLYPVREKFCNLIGPRDR 250
              L+++V SAT++  K   FF            C I  + GR +PV   +     P   
Sbjct: 202 ---LRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPD-- 256

Query: 251 ENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTL 310
               YI++ VE  + IH  E  GD+L FLTGQ E+E    +L + A ++      +    
Sbjct: 257 ----YIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARAL-----ARTGMK 307

Query: 311 DGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLN 370
             L +LP Y  + + +Q ++F      +RK +++TN++ TS+TI GI YV+D GFVK   
Sbjct: 308 RHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRA 367

Query: 371 HNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTS 430
           +NPR  ++ L VVP+S++ A QR+GR GR+ SGKC+R+Y+++ +++ +P   +PE++R++
Sbjct: 368 YNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDK-LPQSTVPEMQRSN 426

Query: 431 LTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTR-LGLSMVEF 489
           L  V+L LK L I +V+RF ++ PP  + +++AL+ LY    +D+   +T  LG+ + EF
Sbjct: 427 LAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEF 486

Query: 490 PLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGG 549
           PL P     ++++ +  C   +L IAAM+ ++N+F+ P  P  +  A + HR+ A + G 
Sbjct: 487 PLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVP--PNQKSHAIRVHRKFAVEEG- 543

Query: 550 FNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPKE 609
             D  T+  I+E        + WCQ+H+++++ L  A  V  QL++L+ K +     P++
Sbjct: 544 --DHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQ----VPRK 597

Query: 610 TFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTVDGRGSPVHIHPSSALHEQETKLEWII 669
           + EG    VL RC+ +G+F N AR      + T+      +HIHP+S L+ ++    W+I
Sbjct: 598 SSEGDPDLVL-RCIVSGFFANAARFHSTGAYRTIRD-DHELHIHPASVLYAEKPP-RWVI 654

Query: 670 FHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVRED 718
           ++EV+ T+K Y R V  I   W+ +L P  ++   H LS  A+R   +D
Sbjct: 655 YNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTH-LSLKAKRAKVQD 702


>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo
           sapiens]
          Length = 707

 Score =  403 bits (1036), Expect = e-112
 Identities = 244/657 (37%), Positives = 371/657 (56%), Gaps = 43/657 (6%)

Query: 52  TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAA 111
           + PI + R +++  +R+    ++ G TGSGKTTQ+P+YLYE G S+ G+I VTQPR+VAA
Sbjct: 73  SLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQGIIAVTQPRRVAA 132

Query: 112 ISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVII 171
           IS+A RV++E +  LG  VGY VRFDD +S++T IK++TDG LL+  + D  L K+S +I
Sbjct: 133 ISLATRVSDEKRTELGKLVGYTVRFDDVTSEDTRIKFLTDGMLLREAISDSLLRKYSCVI 192

Query: 172 LDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIP 231
           LDEAHERT+ TD+LFG++K   + +    K  LKV+VMSATM++   S +F   P+  + 
Sbjct: 193 LDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMDVDLFSQYFNGAPVLYLE 252

Query: 232 GRLYPVREKFCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAG-DILVFLTGQFEIE---K 287
           GR +P++  +        +    Y+ A +     IH    +  DILVFLTGQ EIE   K
Sbjct: 253 GRQHPIQVFYTK------QPQNDYLHAALVSVFQIHQEAPSSQDILVFLTGQEEIEAMSK 306

Query: 288 SCELLFQMAESVDYDYDVQDTTLDG---LLILPCYGSMTTDQQRRIFLPPPPGIRKCVIS 344
           +C              D+     DG   +L+LP Y S+   QQ R+F   P G RK +IS
Sbjct: 307 TCR-------------DIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKVIIS 353

Query: 345 TNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGK 404
           TNI+ TS+TI GI+YVVD G VK   +NP  GL++L V  +SK++A QR+GRAGR  SG 
Sbjct: 354 TNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGI 413

Query: 405 CFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEAL 464
           C+R+Y++D + +      +PEI+R +L SV+L L  + + +V+ F ++  P+   I  A+
Sbjct: 414 CYRLYTEDEFEK-FDKMTVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSKPSPDHIQAAI 472

Query: 465 KQLYQCDAIDRSGH---VTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVE 521
            QL    A++       +T +G  M  FPL P     ++ +    C + +L I ++LSV+
Sbjct: 473 AQLDLLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSLLSVD 532

Query: 522 NVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWR 581
           +V   P  P  ++E +   ++  +  G   D  TL  I+   K+ G    WC++++++ +
Sbjct: 533 SVLHNP--PSRREEVQGVRKKFISSEG---DHMTLLNIYRTFKNLGGNKDWCKENFVNSK 587

Query: 582 CLFSAFRVEAQLRELIRKLKQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFC 641
            +     V AQLR++  K+      P  +  G   E +RRCL    F + A      T+ 
Sbjct: 588 NMTLVAEVRAQLRDICLKM----SMPIASSRGDV-ESVRRCLAHSLFMSTAELQPDGTYA 642

Query: 642 TVDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPK 698
           T D    PV IHPSS L     K   +++ E+L T K Y R +C I  +W+ +  P+
Sbjct: 643 TTDTH-QPVAIHPSSVLF--HCKPACVVYTELLYTNKCYMRDLCVIDAQWLYEAAPE 696


>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
           sapiens]
          Length = 1143

 Score =  313 bits (802), Expect = 4e-85
 Identities = 198/598 (33%), Positives = 325/598 (54%), Gaps = 43/598 (7%)

Query: 14  RQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLI 73
           R    ER  + +   L  +    ++  G  ++        PI +   +I+Q ++++  ++
Sbjct: 123 RHLPAERVAEFRRALLHYLDFGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVV 182

Query: 74  VTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQ 133
           V G+TG GK+TQ+P+YL  AGFS    +  TQPR++A IS+A+RV  E     GS+VGYQ
Sbjct: 183 VAGDTGCGKSTQVPQYLLAAGFSH---VACTQPRRIACISLAKRVGFESLSQYGSQVGYQ 239

Query: 134 VRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLF 193
           +RF+   S  T I ++T G LL+ I  +P+L ++ V+I+DE HER L  D L G+L++L 
Sbjct: 240 IRFESTRSAATKIVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLL 299

Query: 194 QEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENT 253
               P R + LKV++MSAT+ ++  S++F N P+  +PGRL+P+   +     P++ E T
Sbjct: 300 ----PTRPD-LKVILMSATINISLFSSYFSNAPVVQVPGRLFPITVVY----QPQEAEPT 350

Query: 254 AY---------IQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYD 304
                         ++E     +  E  GD+LVFL+G  EI    E     A        
Sbjct: 351 TSKSEKLDPRPFLRVLESIDHKYPPEERGDLLVFLSGMAEISAVLEAAQTYASHTQR--- 407

Query: 305 VQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGG 364
                    ++LP + +++   Q ++F   PPG+RKC++STNI+ TS+TIDGIR+VVD G
Sbjct: 408 --------WVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSG 459

Query: 365 FVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIP 424
            VK+++++P+  L  L+   IS++ A QR GRAGRT  G CFR+Y++  ++   P + +P
Sbjct: 460 KVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAP-YPVP 518

Query: 425 EIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGL 484
           EI+R +L S+VL +K +++ D   FP+++PP    +  A+  L    A+D S  +T +G 
Sbjct: 519 EIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPASLETAILYLRDQGALDSSEALTPIGS 578

Query: 485 SMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELA 544
            + + P+   +   +I  +     + +L IAA LSV++ F R    +   E     R L 
Sbjct: 579 LLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSPFTR--SAQSSPECAAARRPLE 636

Query: 545 AKAGG----FNDF-ATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELI 597
           +  G     FN F A + V  E+ ++S     WC++  I    L+    +  Q +EL+
Sbjct: 637 SDQGDPFTLFNVFNAWVQVKSERSRNS---RKWCRRRGIEEHRLYEMANLRRQFKELL 691


>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
           [Homo sapiens]
          Length = 1008

 Score =  281 bits (719), Expect = 2e-75
 Identities = 205/714 (28%), Positives = 338/714 (47%), Gaps = 110/714 (15%)

Query: 54  PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLY----EAGFSQHGMIGVTQPRKV 109
           P    +K+++  + ++   +++G TG GKTTQ+ +++     E G      I  TQPR++
Sbjct: 208 PSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRI 267

Query: 110 AAISVAQRVAEEM--KCTLGSKVGYQVRFDD-CSSKETAIKYMTDGCLLKHILGDPNLTK 166
           +AISVA+RVA E    C  G+  GYQ+R       K+ +I Y T G +L+ +  DP L+ 
Sbjct: 268 SAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSS 327

Query: 167 FSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCP 226
            S I+LDE HER L +D+L  ++K L      N +  LKV++MSAT+   K S +FGNCP
Sbjct: 328 VSHIVLDEIHERNLQSDVLMTVVKDLL-----NFRSDLKVILMSATLNAEKFSEYFGNCP 382

Query: 227 IFDIPGRLYPV----------------------------------------------REK 240
           +  IPG  +PV                                              +E+
Sbjct: 383 MIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKER 442

Query: 241 FCNLIGPRDRENTAYIQAIVEVTMD--IHLN------------EMAGDILVFLTGQFEIE 286
           + + +    R  +A    ++E+  D  + LN            E  G ILVFL G   I 
Sbjct: 443 WPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNIS 502

Query: 287 KSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTN 346
              +LL                  D  LI+P +  M T  Q ++F   PPG+RK VI+TN
Sbjct: 503 TLHDLLMSQVMFKS----------DKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATN 552

Query: 347 ISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCF 406
           I+ TS+TID + YV+DGG +K+ + + +  +  +    +SK+ A QR GRAGR   G C+
Sbjct: 553 IAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCY 612

Query: 407 RIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRF--PYLDPPNERLILEAL 464
            +Y+       + D+ +PEI RT L  + L +K L +  +  F    +DPP+   +L ++
Sbjct: 613 HLYN-GLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSI 671

Query: 465 KQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVF 524
           + L + +A+D+   +T LG+ +   P+ PH+   ++  A   C D +L IAA LS ++ F
Sbjct: 672 RHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPF 731

Query: 525 IRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIF---EQCKSSG--APASWCQKHWIH 579
           + P+  E  K A+ R +ELA      +D  T+   F   E+ +  G      +C ++++ 
Sbjct: 732 VIPLGKE--KIADARRKELAKDTR--SDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLS 787

Query: 580 WRCLFSAFRVEAQLRELIRKL----KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVA--- 632
              L     ++ Q  E +        +    P+        ++++  +CAG +  VA   
Sbjct: 788 SNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLYPKVAKIR 847

Query: 633 -----RRSVGRTFCTVDGRGSPVHIHPSSALHEQ-ETKLEWIIFHEVLVTTKVY 680
                +R + + +   DG    V +HP S   EQ +    W+I+H  + T+ +Y
Sbjct: 848 LNLGKKRKMVKVYTKTDGL---VAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIY 898


>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
           sapiens]
          Length = 743

 Score =  275 bits (703), Expect = 1e-73
 Identities = 193/718 (26%), Positives = 366/718 (50%), Gaps = 53/718 (7%)

Query: 4   FPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKII 63
           FP     +   +EE     DL+      +  + R  K    +E       PI K++   +
Sbjct: 18  FPESLDSSDGDEEEVLACEDLELNPFDGLPYSSRYYKLLKERED-----LPIWKEKYSFM 72

Query: 64  QAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFS---QHGMIGVTQPRKVAAISVAQRVAE 120
           + +  N  +IV+G+   GK+ Q+P++  E   S   QHG +  TQ  K   + +A RVA+
Sbjct: 73  ENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVHKQTVVQLALRVAD 132

Query: 121 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 180
           EM   +G +VGY + F++C + ET ++Y TD  L + ++ +P L  + VIILD+ HER++
Sbjct: 133 EMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSI 192

Query: 181 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 240
            TD+L GLLK +   +       LK+++ S+   ++KL++++GN P+ ++  + +PV   
Sbjct: 193 ATDVLLGLLKDVLLARP-----ELKLIINSSPHLISKLNSYYGNVPVIEVKNK-HPVEVV 246

Query: 241 FCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 300
           + +     + +  ++ ++I+ +  +IH +   GDI+VFL  + +IEK CE ++Q +    
Sbjct: 247 YLS-----EAQKDSF-ESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVYQGSNL-- 298

Query: 301 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKC-------VISTNISATSLT 353
                 +  L  L+++P Y      ++  +F P     ++C       V++T+     + 
Sbjct: 299 ------NPDLGELVVVPLYPK----EKCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIW 348

Query: 354 IDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDF 413
            + +R+V+D G  ++  +NPR+  + L + PIS+S+A  R    G +SSGK F +Y+++F
Sbjct: 349 SNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEF 408

Query: 414 WNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAI 473
            ++ M      E++  +LTS+VL +K + I  +    +++ P    +++AL+ L    A+
Sbjct: 409 ASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRPAPESLMQALEDLDYLAAL 468

Query: 474 DRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQ 533
           D  G+++  G+ M EFPL P L+ +++ +   DC D +L IAAM++  N F     P   
Sbjct: 469 DNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHV--PHGA 526

Query: 534 KEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPAS-------WCQKHWIHWRCLFSA 586
           +EA     +      G  D  TL  I++  + +   +S       WC+ ++++   L  A
Sbjct: 527 EEAALTCWKTFLHPEG--DHFTLISIYKAYQDTTLNSSSEYCVEKWCRDYFLNCSALRMA 584

Query: 587 FRVEAQLRELIRKLKQQSDFPKETFEGPKHEV-LRRCLCAGYFKNVARRSVGRTFCTVDG 645
             + A+L E+I+++  +  + +  F   ++ + +++ L +GYF  +AR   G     +  
Sbjct: 585 DVIRAELLEIIKRI--ELPYAEPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLMLT 642

Query: 646 RGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFN 703
                 +HP S     +   EW++FH+  ++   Y RI   I  E    L+P+ +  N
Sbjct: 643 HKQVAQLHPLSGYSITKKMPEWVLFHKFSISENNYIRITSEISPELFMQLVPQYYFSN 700


>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
           [Homo sapiens]
          Length = 994

 Score =  270 bits (689), Expect = 5e-72
 Identities = 198/690 (28%), Positives = 336/690 (48%), Gaps = 76/690 (11%)

Query: 54  PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLY----EAGFSQHGMIGVTQPRKV 109
           P    +K+++  + ++   +++G TG GKTTQ+ +++     E G      I  TQPR++
Sbjct: 208 PSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRI 267

Query: 110 AAISVAQRVAEEM--KCTLGSKVGYQVRFDD-CSSKETAIKYMTDGCLLKHILGDPNLTK 166
           +AISVA+RVA E    C  G+  GYQ+R       K+ +I Y T G +L+ +  DP L+ 
Sbjct: 268 SAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLSS 327

Query: 167 FSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCP 226
            S I+LDE HER L +D+L  ++K L      N +  LKV++MSAT+   K S +FGNCP
Sbjct: 328 VSHIVLDEIHERNLQSDVLMTVVKDLL-----NFRSDLKVILMSATLNAEKFSEYFGNCP 382

Query: 227 IFDIPGRLYPVREKFCNLIGPRDR---ENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQF 283
           +  IPG  +PV E     +  + R   E   +        M  H+N    +    +  + 
Sbjct: 383 MIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKER 442

Query: 284 EIEKSCELLFQ-MAESVDYDYDVQDTTLD-------------------GLLILPCYGSMT 323
             +   EL  +  A +VD    ++D  +D                    L+ LP + +++
Sbjct: 443 WPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNIS 502

Query: 324 T-------------DQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLN 370
           T               Q ++F   PPG+RK VI+TNI+ TS+TID + YV+DGG +K+ +
Sbjct: 503 TLHDLLMSQVMFKSVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETH 562

Query: 371 HNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTS 430
            + +  +  +    +SK+ A QR GRAGR   G C+ +Y+       + D+ +PEI RT 
Sbjct: 563 FDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYN-GLRASLLDDYQLPEILRTP 621

Query: 431 LTSVVLTLKCLAIHDVIRF--PYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVE 488
           L  + L +K L +  +  F    +DPP+   +L +++ L + +A+D+   +T LG+ +  
Sbjct: 622 LEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLAR 681

Query: 489 FPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAG 548
            P+ PH+   ++  A   C D +L IAA LS ++ F+ P+  E  K A+ R +ELA    
Sbjct: 682 LPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKE--KIADARRKELAKDTR 739

Query: 549 GFNDFATLAVIF---EQCKSSG--APASWCQKHWIHWRCLFSAFRVEAQLRELIRKL--- 600
             +D  T+   F   E+ +  G      +C ++++    L     ++ Q  E +      
Sbjct: 740 --SDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFV 797

Query: 601 -KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVA--------RRSVGRTFCTVDGRGSPVH 651
             +    P+        ++++  +CAG +  VA        +R + + +   DG    V 
Sbjct: 798 SSRNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGL---VA 854

Query: 652 IHPSSALHEQ-ETKLEWIIFHEVLVTTKVY 680
           +HP S   EQ +    W+I+H  + T+ +Y
Sbjct: 855 VHPKSVNVEQTDFHYNWLIYHLKMRTSSIY 884


>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
           sapiens]
          Length = 717

 Score =  260 bits (664), Expect = 4e-69
 Identities = 202/674 (29%), Positives = 324/674 (48%), Gaps = 77/674 (11%)

Query: 54  PIQKQRKKIIQAVRDN--SFLIVTGNTGSGKTTQLPKYLYEAGFS---QHGMIGVTQPRK 108
           PI   R   ++ +  N    ++V+G  GSGK+TQ+P++  E   +   Q G + VTQP  
Sbjct: 46  PIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQKGQVTVTQPYP 105

Query: 109 VAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFS 168
           +AA S+A RVA+EM  TLG +VGY +  +DC+   T +++  D  LL+ +        + 
Sbjct: 106 LAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRLLLQEVASTRGTGAWG 165

Query: 169 VIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIF 228
           V++LDEA ER++ +D L GLL+    EK P     L+VVV++      KL AF+GN PI 
Sbjct: 166 VLVLDEAQERSVASDSLQGLLQDARLEKLPG---DLRVVVVTDPALEPKLRAFWGNPPIV 222

Query: 229 DIPGRLYPVREKFCNLIGPRDRENTAY--------IQAIVEVTMDIHLNEMAGDILVFLT 280
            IP      RE       P +R +  Y        ++A  +  +++   E+ GD+LVFL 
Sbjct: 223 HIP------RE-------PGERPSPIYWDTIPPDRVEAACQAVLELCRKELPGDVLVFLP 269

Query: 281 GQFEIEKSCELLFQMAESVDYDYDVQDTTLDGL--LILPCYGSMTTDQQRRIFLPPPPGI 338
            + EI   CE L +  ES+          L GL   +LP +       Q    +      
Sbjct: 270 SEEEISLCCESLSREVESL---------LLQGLPPRVLPLHPDCGRAVQA---VYEDMDA 317

Query: 339 RKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAG 398
           RK V++  ++  S ++  I++V+D G   +  +NPR+  +   + PISK +A  R  RA 
Sbjct: 318 RKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRAR 377

Query: 399 RTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNER 458
               G C  +Y K F     P    P +   +L+S+VL LK   I +     +LD P   
Sbjct: 378 GFPPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFLDQPAPE 437

Query: 459 LILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAML 518
            +++AL+ L    A+D  G ++ LG+ + EFPL P L  A++ +   DC D +L +AAML
Sbjct: 438 ALMQALEDLDYLAALDDDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAML 497

Query: 519 SVENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWI 578
           +    F RP  P   +EA  R R L    G   D ++L  ++E    SGA  +WCQ   +
Sbjct: 498 TAAPGFTRP--PLSAEEAALR-RALEHTDG---DHSSLIQVYEAFIQSGADEAWCQARGL 551

Query: 579 HWRCLFSAFRVEAQLRELIRKLKQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVG- 637
           +W  L  A ++  +L EL+++++     P    E  + + L++ L +GYF  VAR + G 
Sbjct: 552 NWAALCQAHKLRGELLELMQRIELPLSLPAFGSEQNRRD-LQKALVSGYFLKVARDTDGT 610

Query: 638 --------------RTFCTVDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARI 683
                          ++C    R +P    P            W+++H   ++      I
Sbjct: 611 GNYLLLTHKHVAQLSSYCCYRSRRAPARPPP------------WVLYHNFTISKDNCLSI 658

Query: 684 VCPIRYEWVRDLLP 697
           V  I+ + + +L P
Sbjct: 659 VSEIQPQMLVELAP 672


>gi|166851804 tudor domain containing 9 [Homo sapiens]
          Length = 1382

 Score =  246 bits (627), Expect = 8e-65
 Identities = 171/523 (32%), Positives = 276/523 (52%), Gaps = 50/523 (9%)

Query: 48  GTT---PTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYE--AGFSQHGMIG 102
           GTT   P  PI + +++++  +  NS +I+ G TGSGK+TQLP+Y+ +     S +  I 
Sbjct: 124 GTTYKYPDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYCSIV 183

Query: 103 VTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDP 162
           VTQPRK+ A S+A+ +++E   TLG  VGYQV  +  ++++T + YMT G LL+ I+   
Sbjct: 184 VTQPRKIGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAK 243

Query: 163 NLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFF 222
           +L +F+ II+DE HERT   D L  +++KL +  S      +KVV+MSAT+   + + +F
Sbjct: 244 SLMEFTHIIIDEVHERTEEMDFLLLVVRKLLRTNS----RFVKVVLMSATISCKEFADYF 299

Query: 223 G--------NCPIFDIPGRLYPVREKFCN--------LIGPRDRENTAYIQAIVEVTMDI 266
                       IF++ G+ + V E + N         + P   E     + I EV   +
Sbjct: 300 AVPVQNKMNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVA--V 357

Query: 267 HLNEMAGDILVFLTG-------QFEIEKSCELLFQMA-ESVDYDYDVQDTTLDGLL-ILP 317
            L +M  D+ +  +G       QF +E+S  L+F      ++Y +++  + +   L + P
Sbjct: 358 SLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHKRLQVYP 417

Query: 318 CYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGL 377
            + S+  ++Q  +FL P PG RK ++STNI+ +S+T+  ++YV+D    + L  +     
Sbjct: 418 LHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNY 477

Query: 378 DILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLT 437
             L +   SK+   QR GRAGR S G C+R+  KDFW+  +PDHV+PE+ R  L S +L 
Sbjct: 478 QSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILK 537

Query: 438 LKCLAIHD--VIRFPYLDPPN----ERLILEALKQL-------YQCDAIDRSGHVTRLGL 484
           +K L + +   +    L PP     ER IL  LK++        + D     G +T LG 
Sbjct: 538 VKLLDMGEPRALLATALSPPGLSDIERTIL-LLKEVGALAVSGQREDENPHDGELTFLGR 596

Query: 485 SMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRP 527
            + + P+   L   ++      C D  L IAA LS++N F  P
Sbjct: 597 VLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMP 639


>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2
           [Homo sapiens]
          Length = 1155

 Score =  238 bits (608), Expect = 1e-62
 Identities = 169/538 (31%), Positives = 275/538 (51%), Gaps = 47/538 (8%)

Query: 23  DLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGK 82
           + +E RLS   +     +G   QE    P  P+   R  I+ A+  +  ++++G+TG GK
Sbjct: 368 EAEEVRLSQSLLELWRRRGPVWQEA---PQLPVDPHRDTILNAIEQHPVVVISGDTGCGK 424

Query: 83  TTQLPKYLYEA----GFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDD 138
           TT++P+ L E     G      + +TQPR+++A+SVAQRV+ E+  +L   VG+QVR + 
Sbjct: 425 TTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLES 484

Query: 139 CS-SKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKS 197
              S+  A+ + T G LL+ +  +P+L   S +I+DE HER + TD L  LLK L Q  +
Sbjct: 485 KPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGL-QRLN 543

Query: 198 PNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPR--------- 248
           P     L++V+MSAT +  + S +FG CP+  +PG +YPV+E +   I  +         
Sbjct: 544 PA----LRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHR 599

Query: 249 ------DRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYD 302
                 + E    +  + ++ + I      G IL FL G  EI+   + L +     +  
Sbjct: 600 HRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESK 659

Query: 303 YDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVD 362
           Y          LILP + ++    Q+ IF  PP G+RK V++TNI+ TS+TI+ I +VVD
Sbjct: 660 Y----------LILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVD 709

Query: 363 GGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHV 422
            G  K+  ++ +  +  LE V +S++  +QR GRAGR  SG  + ++ +    + +P  V
Sbjct: 710 SGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQV 769

Query: 423 IPEIKRTSLTSVVLTLKC-LAIHDVIRF--PYLDPPNERLILEALKQLYQCDAIDRSGHV 479
            PEI RT L ++VL  K  +     + F    +D PN + + EA+  L +   +D+  ++
Sbjct: 770 -PEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYL 828

Query: 480 TRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAE 537
           T LG  +      P L  A++ AA   C   LL + + L+ +     P     Q  AE
Sbjct: 829 TTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRD-----PFSSSLQNRAE 881


>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1
           [Homo sapiens]
          Length = 1194

 Score =  238 bits (608), Expect = 1e-62
 Identities = 169/538 (31%), Positives = 275/538 (51%), Gaps = 47/538 (8%)

Query: 23  DLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGK 82
           + +E RLS   +     +G   QE    P  P+   R  I+ A+  +  ++++G+TG GK
Sbjct: 407 EAEEVRLSQSLLELWRRRGPVWQEA---PQLPVDPHRDTILNAIEQHPVVVISGDTGCGK 463

Query: 83  TTQLPKYLYEA----GFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDD 138
           TT++P+ L E     G      + +TQPR+++A+SVAQRV+ E+  +L   VG+QVR + 
Sbjct: 464 TTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLES 523

Query: 139 CS-SKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKS 197
              S+  A+ + T G LL+ +  +P+L   S +I+DE HER + TD L  LLK L Q  +
Sbjct: 524 KPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGL-QRLN 582

Query: 198 PNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPR--------- 248
           P     L++V+MSAT +  + S +FG CP+  +PG +YPV+E +   I  +         
Sbjct: 583 PA----LRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHR 638

Query: 249 ------DRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYD 302
                 + E    +  + ++ + I      G IL FL G  EI+   + L +     +  
Sbjct: 639 HRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESK 698

Query: 303 YDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVD 362
           Y          LILP + ++    Q+ IF  PP G+RK V++TNI+ TS+TI+ I +VVD
Sbjct: 699 Y----------LILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVD 748

Query: 363 GGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHV 422
            G  K+  ++ +  +  LE V +S++  +QR GRAGR  SG  + ++ +    + +P  V
Sbjct: 749 SGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQV 808

Query: 423 IPEIKRTSLTSVVLTLKC-LAIHDVIRF--PYLDPPNERLILEALKQLYQCDAIDRSGHV 479
            PEI RT L ++VL  K  +     + F    +D PN + + EA+  L +   +D+  ++
Sbjct: 809 -PEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYL 867

Query: 480 TRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAE 537
           T LG  +      P L  A++ AA   C   LL + + L+ +     P     Q  AE
Sbjct: 868 TTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRD-----PFSSSLQNRAE 920


>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
          Length = 1270

 Score =  228 bits (581), Expect = 2e-59
 Identities = 194/708 (27%), Positives = 324/708 (45%), Gaps = 103/708 (14%)

Query: 54   PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM-----IGVTQPRK 108
            P++K   +I++A+  NS +I+ G TG GKTTQ+P+++ +  F Q+       I VTQPR+
Sbjct: 389  PVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILD-DFIQNDRAAECNIVVTQPRR 447

Query: 109  VAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETA-IKYMTDGCLLKHILGDPNLTKF 167
            ++A+SVA+RVA E     G   GY VRF+    +  A I + T G LL+ +  +  +   
Sbjct: 448  ISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKL--EAGIRGI 505

Query: 168  SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227
            S +I+DE HER + TD L  +L+ + Q         +++V+MSAT++ +    +F NCPI
Sbjct: 506  SHVIVDEIHERDINTDFLLVVLRDVVQAYP-----EVRIVLMSATIDTSMFCEYFFNCPI 560

Query: 228  FDIPGRLYPVREKF---------------------------------CNLI-----GPRD 249
             ++ GR YPV+E F                                 CNLI     GP  
Sbjct: 561  IEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGPET 620

Query: 250  R-------ENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYD 302
            R       E     + I  +   I    + G +LVFL G         L++ M + ++ +
Sbjct: 621  RLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGW-------NLIYTMQKHLEMN 673

Query: 303  YDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVD 362
                        ILP +  +  ++QR++F P P G+ K ++STNI+ TS+TI+ + YV+D
Sbjct: 674  PHFGSHRYQ---ILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVID 730

Query: 363  GGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHV 422
                K         +     V  SK+   QR GRAGR   G CF + S+  + + +  H+
Sbjct: 731  SCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFER-LETHM 789

Query: 423  IPEIKRTSLTSVVLTLKCLAIHDVIRF--PYLDPPNERLILEALKQLYQCDAIDRSGHVT 480
             PE+ RT L  + L++K L +  + +F    ++PP    ++EA   L + DA+D +  +T
Sbjct: 790  TPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELT 849

Query: 481  RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH 540
             LG  + + P+ P     +I        D +  IAA       FI        K     H
Sbjct: 850  PLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINE-----GKRLGYIH 904

Query: 541  RELAAKAGGFNDFATLAVIF---EQCKSSGAPAS--WCQKHWIHWRCLFSAFRVEAQLRE 595
            R  A     F+D   L  +F   +  +  G  A   +C+   ++   L   +  + QL+E
Sbjct: 905  RNFAGNR--FSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKE 962

Query: 596  LIRKLKQQSDFPKE-------TFEGPKH--EVLRRCLCAGYFKNVARRSVGRTFCTVDGR 646
            ++      S FP++       T  GP +  +V+   L  G + NV      R   T +GR
Sbjct: 963  IL----INSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGR 1018

Query: 647  GSPVH---IHPSSALHEQETKLEWIIFHEVLVTTKVYAR---IVCPIR 688
             + +H   ++   +  + +    + +F E + T  + A+   +V P++
Sbjct: 1019 NALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQ 1066


>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
          Length = 1369

 Score =  228 bits (581), Expect = 2e-59
 Identities = 193/722 (26%), Positives = 338/722 (46%), Gaps = 102/722 (14%)

Query: 54   PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGF-----SQHGMIGVTQPRK 108
            P+ K R  I++ ++ +  ++V G TGSGK+TQ+P +L E        +    I  TQPR+
Sbjct: 573  PVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPRR 632

Query: 109  VAAISVAQRVAEEMKCTLG-----SKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPN 163
            ++A+S+A RV +E+ C  G     S  GYQ+R +  + + T + Y T G LL+ +  D  
Sbjct: 633  ISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQEDGL 692

Query: 164  LTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFG 223
            L+  S +I+DE HER++ +D L  +LK++ Q++S      L +++MSAT++  K S +F 
Sbjct: 693  LSNVSHVIVDEVHERSVQSDFLLIILKEILQKRS-----DLHLILMSATVDSEKFSTYFT 747

Query: 224  NCPIFDIPGRLYPVR----EKFCNLIGPRDRENTAYIQAIVEVTMDIHLN--EMAGDI-- 275
            +CPI  I GR YPV     E      G    +++ Y Q  +E   ++ +N    AG I  
Sbjct: 748  HCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINVTSKAGGIKK 807

Query: 276  ----LVFLTG----------QFEIEKSCELLFQMAESVDYDY----------DVQDTTLD 311
                +   TG          ++       +L+     ++ D             Q   ++
Sbjct: 808  YQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIE 867

Query: 312  G--LLILP-------CYGSMTTDQ--------------------QRRIFLPPPPGIRKCV 342
            G  L+ LP        Y  ++ D+                    Q   F  PPPG+RK V
Sbjct: 868  GAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIV 927

Query: 343  ISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSS 402
            ++TNI+ T +TI  + +V+D G  K+  ++    +  L    +SK+ ALQR GRAGR   
Sbjct: 928  LATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRD 987

Query: 403  GKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVL-TLKC-LAIHDVIRFPYLDPPNERLI 460
            G CFR+Y+++ +   M D+ +PEI R  L  + L  +KC L   +      LDPP  ++I
Sbjct: 988  GFCFRMYTRERFEGFM-DYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVI 1046

Query: 461  LEALKQLYQCDAID-RSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLS 519
              A+  L +  A +     +T LG  +   P+   +   +I  A   C D +  +AA+++
Sbjct: 1047 SNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMT 1106

Query: 520  VENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSG---APASWCQKH 576
             ++ F  P+    + EA+     LA             + +++ +  G   +  ++C+++
Sbjct: 1107 EKSPFTTPIG--RKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRN 1164

Query: 577  WIHWRCLFSAFRVEAQLRELIRKLKQQSDFPKETFEGPKHE---------VLRRCLCAGY 627
            +++   L +   V+ +L +L++     S     ++EG +           +L+  L AG 
Sbjct: 1165 FLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVAGL 1224

Query: 628  FKNVAR----RSVGRT---FCTVDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVY 680
            + NV +    +SV  T    C V+       +HPSS   + +T   W+++ E +   +VY
Sbjct: 1225 YDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQTH-GWLLYQEKIRYARVY 1283

Query: 681  AR 682
             R
Sbjct: 1284 LR 1285


>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapiens]
          Length = 1157

 Score =  171 bits (433), Expect = 2e-42
 Identities = 130/457 (28%), Positives = 209/457 (45%), Gaps = 60/457 (13%)

Query: 300  DYDYDVQDTTLDG---------LLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISAT 350
            D D D+ D   DG         L +LP Y  +  ++Q ++F PPP G R CV++TN++ T
Sbjct: 566  DLDLDLGDGGQDGGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAET 625

Query: 351  SLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYS 410
            SLTI GI+YVVD G VK+  ++   G+    V  +S++ A QR+GRAGRT  G C+R+YS
Sbjct: 626  SLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYS 685

Query: 411  KDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQC 470
               +         PEI R  +  ++L +K L +  VI FP+  PP+   +L A + L   
Sbjct: 686  SAVFGD-FEQFPPPEITRRPVEDLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIAL 744

Query: 471  DAID---------------RSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIA 515
             A+                 S  +T LG +M  FP+ P     +  +    C    + I 
Sbjct: 745  GALQPPQKAERVKQLQENRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIV 804

Query: 516  AMLSVENVF---IRPV--DPEYQKEAEQRHRELAAK---AG-----GFNDFATLAVIFEQ 562
            A ++V  +F    RP   D E  +   +R R    K   AG        D   L      
Sbjct: 805  ASMTVRELFEELDRPAASDEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGA 864

Query: 563  CKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPKETFEGPKHE----- 617
            C+ +     +C+ + + ++ +    R+  QL   +  +  ++    E F  PK +     
Sbjct: 865  CEYASCTPQFCEANGLRYKAMMEIRRLRGQLTTAVNAVCPEA----ELFVDPKMQPPTES 920

Query: 618  ---VLRRCLCAGYFKNVARRSVGRTFCTVDGRGS--------PVHIHPSSALHEQETKLE 666
                LR+ + AG   ++ARR           R +        PV IHPSS L ++    E
Sbjct: 921  QVTYLRQIVTAGLGDHLARRVQSEEMLEDKWRNAYKTPLLDDPVFIHPSSVLFKELP--E 978

Query: 667  WIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFN 703
            ++++ E++ TTK+Y + V  +  +W+  LLP   +F+
Sbjct: 979  FVVYQEIVETTKMYMKGVSSVEVQWIPALLPSYCQFD 1015



 Score =  168 bits (426), Expect = 2e-41
 Identities = 109/278 (39%), Positives = 157/278 (56%), Gaps = 34/278 (12%)

Query: 20  RSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTG 79
           RS ++QEERL                        PI  + + I++AV ++  +IV G TG
Sbjct: 241 RSPEMQEERLK----------------------LPILSEEQVIMEAVAEHPIVIVCGETG 278

Query: 80  SGKTTQLPKYLYEAGFS-QHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDD 138
           SGKTTQ+P++LYEAGFS +  +IGVT+PR+VAA++++QRVA+EM  +    V YQ+R++ 
Sbjct: 279 SGKTTQVPQFLYEAGFSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLSQ-RVVSYQIRYEG 337

Query: 139 CSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSP 198
             ++ET IK+MTDG LLK I  D  L ++ V+I+DEAHER++ TDIL GLL ++   ++ 
Sbjct: 338 NVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRA- 396

Query: 199 NRKEHLKVVVMSATMELAKLS----AFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTA 254
            R   LK+++MSAT+ +   +     F    P+  +  R +PV   F       D     
Sbjct: 397 KRNLPLKLLIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLED----- 451

Query: 255 YIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELL 292
           Y          IH    AG ILVFLTGQ E+   C  L
Sbjct: 452 YSGECFRKVCKIHRMLPAGGILVFLTGQAEVHALCRRL 489


>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
            sapiens]
          Length = 1386

 Score =  152 bits (385), Expect = 9e-37
 Identities = 124/483 (25%), Positives = 231/483 (47%), Gaps = 60/483 (12%)

Query: 249  DRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDT 308
            ++ N   I+A++E  +D   +   G ILVFL G  EI+    +L++  +S        + 
Sbjct: 824  EKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIK----MLYEQLQSNSL---FNNR 876

Query: 309  TLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQ 368
              +  +I P + S+++++Q+ +F+ PP G+ K +ISTNI+ TS+TID + YV+D G +K+
Sbjct: 877  RSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKE 936

Query: 369  LNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKR 428
              ++   G++ LE   +S++ ALQR GRAGR +SG CF +++   +N  +    +PEI+R
Sbjct: 937  KRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQR 996

Query: 429  TSLTSVVLTLKCLAIHDV-----IRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLG 483
              L  + L +K L +        +    ++PP+   +  +  +L    A+     +T LG
Sbjct: 997  VPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLG 1056

Query: 484  LSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHREL 543
              +   P+   +   ++  +   C D  L IAA L+ ++ F+ P D   ++EA Q+  E 
Sbjct: 1057 YHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDK--KEEANQKKLEF 1114

Query: 544  AAKAGGFNDFATLAVIFEQCKSSGAPAS--WCQKHWIHWRCLFSAFRVEAQLRELI---- 597
            A     +         ++     G  AS  +C+++++  R L     ++ Q  EL+    
Sbjct: 1115 AFANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIG 1174

Query: 598  --------RKLKQQS-----------DFPKETFEGPKHEVLRRCLCAGYFKNV--ARRSV 636
                    R++++++           +      E PK  ++   LCA  + NV   +   
Sbjct: 1175 FAREGLRAREIEKRAQGGDGVLDATGEEANSNAENPK--LISAMLCAALYPNVVQVKSPE 1232

Query: 637  GRTFCTVDG--RGSP--------------VHIHPSSALHE-QETKLEWIIFHEVLVTTKV 679
            G+   T  G  R  P              VHIHPSS  ++ +     ++++HE + T++V
Sbjct: 1233 GKFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRV 1292

Query: 680  YAR 682
            + R
Sbjct: 1293 FIR 1295



 Score =  136 bits (342), Expect = 9e-32
 Identities = 73/194 (37%), Positives = 118/194 (60%), Gaps = 9/194 (4%)

Query: 52  TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFS----QHGMIGVTQPR 107
           + P  ++R+ I+  +R +  ++++G TG GKTTQ+P+++ +   +    +   I  TQPR
Sbjct: 543 SLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPR 602

Query: 108 KVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKF 167
           +++AISVA+RVA+E    +G  VGYQ+R +   S  T + Y T G LL+ + GD  L   
Sbjct: 603 RISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQGV 662

Query: 168 SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227
           S II+DE HERT  +D L  +LK +      +++  L+V++MSAT+     S +F +CP+
Sbjct: 663 SHIIVDEVHERTEESDFLLLVLKDIV-----SQRPGLQVILMSATLNAELFSDYFNSCPV 717

Query: 228 FDIPGRLYPVREKF 241
             IPGR +PV + F
Sbjct: 718 ITIPGRTFPVDQFF 731


>gi|38505213 YTH domain containing 2 [Homo sapiens]
          Length = 1430

 Score =  150 bits (378), Expect = 6e-36
 Identities = 115/407 (28%), Positives = 195/407 (47%), Gaps = 27/407 (6%)

Query: 272  AGDILVFLTGQFEIEKSCE-LLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRI 330
            AG +L+FL G  EI    + +LF      D  +  Q        +   + +M T  Q+++
Sbjct: 622  AGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQ--------VFMLHSNMQTSDQKKV 673

Query: 331  FLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEA 390
               PP G+RK ++STNI+ TS+T++ + +V+D G VK+ + +    + +L++V ISK+ A
Sbjct: 674  LKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASA 733

Query: 391  LQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFP 450
            +QR GRAGR   G CFR++S+    Q M +   PE+ R  L  + L  K LA  +     
Sbjct: 734  IQRKGRAGRCRPGICFRLFSR-LRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIAD 792

Query: 451  YL----DPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLD 506
            +L    +PP   ++  A++ L   DA+D    +T LG  + + P+ PHL   V+ A  L 
Sbjct: 793  FLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLK 852

Query: 507  CEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIF---EQC 563
            C D +L IA  L+  + F+ P     ++ A    +     AG F+D   L   F   ++ 
Sbjct: 853  CLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFT--AGAFSDHMALLRAFQAWQKA 910

Query: 564  KSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIR-----KLKQQSDFPKETFEGPKHEV 618
            +S G   ++C+K+++    +     +  QL   +R     + +   D            V
Sbjct: 911  RSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAV 970

Query: 619  LRRCLCAGYFKNVARRSVGRTFCTVDG-RGSPVHIHPSSALHEQETK 664
            ++  L AG + N+    V R    + G +   V  HP+S L + + K
Sbjct: 971  VKAALVAGMYPNLVH--VDRENLVLTGPKEKKVRFHPASVLSQPQYK 1015



 Score =  132 bits (332), Expect = 1e-30
 Identities = 71/194 (36%), Positives = 126/194 (64%), Gaps = 10/194 (5%)

Query: 52  TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM---IGVTQPRK 108
           + P+ +++++I++ +++N  +++ G TGSGKTTQ+P++L +  F ++G+   I  TQPR+
Sbjct: 192 SLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCF-KNGIPCRIFCTQPRR 250

Query: 109 VAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHIL-GDPNLTKF 167
           +AAI+VA+RVA E +  +G  +GYQ+R +   S +T + + T+G LL+ ++ GD  L+  
Sbjct: 251 LAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTV 310

Query: 168 SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227
           + +I+DE HER   +D L   L+ L Q K P     LK+++ SA +++     +FG+CP+
Sbjct: 311 THVIVDEVHERDRFSDFLLTKLRDLLQ-KHPT----LKLILSSAALDVNLFIRYFGSCPV 365

Query: 228 FDIPGRLYPVREKF 241
             I GR + V+E F
Sbjct: 366 IYIQGRPFEVKEMF 379


>gi|19923796 NMD3 homolog [Homo sapiens]
          Length = 503

 Score = 34.7 bits (78), Expect = 0.35
 Identities = 41/163 (25%), Positives = 66/163 (40%), Gaps = 19/163 (11%)

Query: 326 QQRRIFLPPPPGIRKCVISTNISATSLT-----IDGIRYVVDGGFVKQLNHNPRLGLDIL 380
           Q +R F PP   I+  + S  + A  L      +  +R +VD GFV    H+ RL + + 
Sbjct: 57  QCQRYFQPPGTWIQCALESRELLALCLKKIKAPLSKVR-LVDAGFVWTEPHSKRLKVKLT 115

Query: 381 EVVPISKSEALQR----SGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRT--SLTSV 434
               +     LQ+             G C R+ +KDFW   +        K+T   L  +
Sbjct: 116 IQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQL 175

Query: 435 VL-------TLKCLAIHDVIRFPYLDPPNERLILEALKQLYQC 470
           +L       TL+   IHD + F Y    + + ++E L+    C
Sbjct: 176 ILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQCTVPC 218


>gi|66472922 muscle-related coiled-coil protein [Homo sapiens]
          Length = 364

 Score = 33.5 bits (75), Expect = 0.78
 Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 4/77 (5%)

Query: 706 DLSSVARREVRED--ARRRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFL-E 762
           DLSS     V E   AR R + KE++  +K   SK+ ++K  R+N DK ++  R R +  
Sbjct: 170 DLSSDEEYYVEESRSARLRKSGKEHIDNIKKAFSKENMQK-TRQNLDKKVNRIRTRIVTP 228

Query: 763 RKQQRTQDHSDTRKETG 779
            +++R +   +  +++G
Sbjct: 229 ERRERLRQSGERLRQSG 245


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 295   MAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTI 354
             + E  +Y+Y V      GL  LP   S     +  +FLP PP   K V S     T++TI
Sbjct: 26047 LREGCEYEYRVYAENAAGLS-LPSETSPLIRAEDPVFLPSPPSKPKIVDS---GKTTITI 26102

Query: 355   DGIRYVVDGG 364
               ++ + DGG
Sbjct: 26103 AWVKPLFDGG 26112


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 295   MAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTI 354
             + E  +Y+Y V      GL  LP   S     +  +FLP PP   K V S     T++TI
Sbjct: 19742 LREGCEYEYRVYAENAAGLS-LPSETSPLIRAEDPVFLPSPPSKPKIVDS---GKTTITI 19797

Query: 355   DGIRYVVDGG 364
               ++ + DGG
Sbjct: 19798 AWVKPLFDGG 19807


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 295   MAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTI 354
             + E  +Y+Y V      GL  LP   S     +  +FLP PP   K V S     T++TI
Sbjct: 19675 LREGCEYEYRVYAENAAGLS-LPSETSPLIRAEDPVFLPSPPSKPKIVDS---GKTTITI 19730

Query: 355   DGIRYVVDGG 364
               ++ + DGG
Sbjct: 19731 AWVKPLFDGG 19740


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 295   MAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTI 354
             + E  +Y+Y V      GL  LP   S     +  +FLP PP   K V S     T++TI
Sbjct: 19550 LREGCEYEYRVYAENAAGLS-LPSETSPLIRAEDPVFLPSPPSKPKIVDS---GKTTITI 19605

Query: 355   DGIRYVVDGG 364
               ++ + DGG
Sbjct: 19606 AWVKPLFDGG 19615


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 81/384 (21%), Positives = 142/384 (36%), Gaps = 69/384 (17%)

Query: 48  GTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPR 107
           G T  FPIQ    K    V +   LI    TG+GKT      L E        I  ++  
Sbjct: 156 GVTYLFPIQV---KTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQETIKKSRSP 212

Query: 108 KVAAIS----VAQRVAEEMK---------CTLGSKVGYQVRFDDCSSKETAIKYMTDGCL 154
           KV  ++    +A +VA++ K         C  G    YQ + +   +    I   T G +
Sbjct: 213 KVLVLAPTRELANQVAKDFKDITRKLSVACFYGG-TSYQSQINHIRN-GIDILVGTPGRI 270

Query: 155 LKHI-LGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATM 213
             H+  G  +L+K   ++LDE  ++ L       +   + +    + +++ + ++ SAT 
Sbjct: 271 KDHLQSGRLDLSKLRHVVLDEV-DQMLDLGFAEQVEDIIHESYKTDSEDNPQTLLFSAT- 328

Query: 214 ELAKLSAFFGNCP--IFDIPGRLYPVREKFCNLIGPRDRENTAYIQAIVEVTMDIHLNE- 270
                      CP  ++ +  +    R +  +L+G   ++    ++    + +  H ++ 
Sbjct: 329 -----------CPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVE---HLAIQCHWSQR 374

Query: 271 --MAGDIL-VFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQ 327
             + GD+L V+   +      CE    + E     +  Q+          C        Q
Sbjct: 375 PAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQNA--------QCLHGDIAQSQ 426

Query: 328 RRIFLPP-PPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPIS 386
           R I L     G  K +++TN++A  L I                  P + L I    P  
Sbjct: 427 REITLKGFREGSFKVLVATNVAARGLDI------------------PEVDLVIQSSPPQD 468

Query: 387 KSEALQRSGRAGRTS-SGKCFRIY 409
               + RSGR GR   +G C   Y
Sbjct: 469 VESYIHRSGRTGRAGRTGICICFY 492


>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
          Length = 2986

 Score = 30.8 bits (68), Expect = 5.0
 Identities = 18/80 (22%), Positives = 38/80 (47%), Gaps = 9/80 (11%)

Query: 659 HEQETKLEWIIFHEVLVTTKVYARIVCPIRYE---WVRDLLPKLHEFNAHDLSSVARREV 715
           HE++ KL+      + +  +++ +    +  E   W  DLL ++++FN  DL+   +R  
Sbjct: 759 HERKIKLD------IFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQ 812

Query: 716 REDARRRWTNKENVKQLKDG 735
           R   R+   N    + ++ G
Sbjct: 813 RHTERKLAMNNMTFEVIQQG 832


>gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]
          Length = 1663

 Score = 30.8 bits (68), Expect = 5.0
 Identities = 18/80 (22%), Positives = 38/80 (47%), Gaps = 9/80 (11%)

Query: 659 HEQETKLEWIIFHEVLVTTKVYARIVCPIRYE---WVRDLLPKLHEFNAHDLSSVARREV 715
           HE++ KL+      + +  +++ +    +  E   W  DLL ++++FN  DL+   +R  
Sbjct: 759 HERKIKLD------IFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQ 812

Query: 716 REDARRRWTNKENVKQLKDG 735
           R   R+   N    + ++ G
Sbjct: 813 RHTERKLAMNNMTFEVIQQG 832


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,694,391
Number of Sequences: 37866
Number of extensions: 1307289
Number of successful extensions: 3632
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 3496
Number of HSP's gapped (non-prelim): 76
length of query: 779
length of database: 18,247,518
effective HSP length: 110
effective length of query: 669
effective length of database: 14,082,258
effective search space: 9421030602
effective search space used: 9421030602
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.