BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31044440 K+ channel tetramerization protein [Homo sapiens] (475 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31044440 K+ channel tetramerization protein [Homo sapiens] 969 0.0 gi|40255182 potassium channel tetramerisation domain containing ... 486 e-137 gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens] 45 1e-04 gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens] 45 1e-04 gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 43 7e-04 gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 43 7e-04 gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 42 0.001 gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 42 0.002 gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] 42 0.002 gi|52426743 cisplatin resistance-associated overexpressed protei... 41 0.002 gi|19923485 cisplatin resistance-associated overexpressed protei... 41 0.002 gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 40 0.005 gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 40 0.006 gi|60097902 filaggrin [Homo sapiens] 40 0.006 gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens] 40 0.006 gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens] 40 0.006 gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens] 40 0.006 gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform ... 39 0.008 gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform ... 39 0.008 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 39 0.010 gi|50962882 G patch domain containing 8 [Homo sapiens] 39 0.010 gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 39 0.013 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 38 0.018 gi|113415504 PREDICTED: similar to ribonucleic acid binding prot... 38 0.023 gi|169166499 PREDICTED: similar to ribonucleic acid binding prot... 38 0.023 gi|113415498 PREDICTED: similar to ribonucleic acid binding prot... 38 0.023 gi|88973230 PREDICTED: similar to ribonucleic acid binding prote... 38 0.023 gi|58331242 formin homology 2 domain containing 3 [Homo sapiens] 37 0.030 gi|169166609 PREDICTED: similar to ribonucleic acid binding prot... 37 0.030 gi|113415994 PREDICTED: similar to ribonucleic acid binding prot... 37 0.030 >gi|31044440 K+ channel tetramerization protein [Homo sapiens] Length = 475 Score = 969 bits (2504), Expect = 0.0 Identities = 475/475 (100%), Positives = 475/475 (100%) Query: 1 MAGRPHPYDGNSSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHER 60 MAGRPHPYDGNSSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHER Sbjct: 1 MAGRPHPYDGNSSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHER 60 Query: 61 SRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASP 120 SRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASP Sbjct: 61 SRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASP 120 Query: 121 NGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSERVTLIVDNTRFVV 180 NGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSERVTLIVDNTRFVV Sbjct: 121 NGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSERVTLIVDNTRFVV 180 Query: 181 DPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCP 240 DPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCP Sbjct: 181 DPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCP 240 Query: 241 DGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVAS 300 DGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVAS Sbjct: 241 DGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVAS 300 Query: 301 AQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLK 360 AQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLK Sbjct: 301 AQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLK 360 Query: 361 ERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCV 420 ERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCV Sbjct: 361 ERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCV 420 Query: 421 KSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPSGNSDLDPDAQNPML 475 KSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPSGNSDLDPDAQNPML Sbjct: 421 KSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPSGNSDLDPDAQNPML 475 >gi|40255182 potassium channel tetramerisation domain containing 20 [Homo sapiens] Length = 419 Score = 486 bits (1252), Expect = e-137 Identities = 225/289 (77%), Positives = 263/289 (91%) Query: 167 ERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFR 226 E+VTL+VD TRFVV+P IFTA P+TMLGRMFG GRE+NFTRPNEKGEYE+AEGI +TVFR Sbjct: 117 EKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFR 176 Query: 227 AILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFE 286 +LDYYKTGII CPDGISIP+LR+ CDYLCI+F+++TI+C+DLSAL+HELSNDGA +QF+ Sbjct: 177 TVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFD 236 Query: 287 FYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFF 346 YLEE+ILP+MV A+ GERECHIVVLTD+D VDWDE++PP MGEEYSQI+YS+KLYRFF Sbjct: 237 HYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFF 296 Query: 347 KYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWE 406 KYIENRDVAK+VLKERGLK IR+GIEGYPT KEK+K+RPGGR EVIYNYVQRPFI+MSWE Sbjct: 297 KYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWE 356 Query: 407 KEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDIL 455 KEEGKSRHVDFQCV+SKS+TNL AA D+ +DQ ++MH PQVDELD L Sbjct: 357 KEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDELDRL 405 >gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens] Length = 338 Score = 45.1 bits (105), Expect = 1e-04 Identities = 37/106 (34%), Positives = 51/106 (48%), Gaps = 7/106 (6%) Query: 40 AKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRD-SSHERTESQLTPCIRNVTSPTRQHH 98 A+GG+ + + H SR R RS RSR S +R + RN ++ T Q Sbjct: 108 ARGGLSGPQGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQ-- 165 Query: 99 VEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSCK 144 ER K + R R +S + S SS+ +SS +SS SSSDG K Sbjct: 166 -ERSKQKARRR---TRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKK 207 >gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens] Length = 341 Score = 45.1 bits (105), Expect = 1e-04 Identities = 37/106 (34%), Positives = 51/106 (48%), Gaps = 7/106 (6%) Query: 40 AKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRD-SSHERTESQLTPCIRNVTSPTRQHH 98 A+GG+ + + H SR R RS RSR S +R + RN ++ T Q Sbjct: 108 ARGGLSGPQGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQ-- 165 Query: 99 VEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSCK 144 ER K + R R +S + S SS+ +SS +SS SSSDG K Sbjct: 166 -ERSKQKARRR---TRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKK 207 >gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] Length = 494 Score = 42.7 bits (99), Expect = 7e-04 Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 4/148 (2%) Query: 24 SRPRKLYKHSSTSSRIAKGGVDHTKMSLH---GASGGHERSRDRRRSSDRSRDSSHERTE 80 SR R+ Y S + SR ++ H++ S + H +SR R RS RSR S R++ Sbjct: 179 SRRRRSYSRSRSHSR-SRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237 Query: 81 SQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSD 140 S+ SP+++ R SR S + + + SR+ S+ S Sbjct: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSK 297 Query: 141 GSCKTAGEMVFVYENAKEGARNIRTSER 168 ++ + V E + R+ E+ Sbjct: 298 SKSRSRSQERRVEEEKRGSVSRGRSQEK 325 Score = 37.7 bits (86), Expect = 0.023 Identities = 44/177 (24%), Positives = 63/177 (35%), Gaps = 33/177 (18%) Query: 23 HSRPRKLYKHSSTS-SRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDS------- 74 HSR R +HS S SR H+K SG RS+ R RS RSR Sbjct: 191 HSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSP 250 Query: 75 --------------SHERTESQLTPCIRN--------VTSPTRQHHVEREKDHSSSRPSS 112 S +++ Q I+N SP+R H + K S S+ Sbjct: 251 SKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR--HKSKSKSRSRSQERR 308 Query: 113 PRPQKASPNGSISSAGNSSRNS-SQSSSDGSCKTAGEMVFVYENAKEGARNIRTSER 168 +K S S R S S+S S G ++ ++ ++G + R R Sbjct: 309 VEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESR 365 Score = 37.4 bits (85), Expect = 0.030 Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 19/125 (15%) Query: 28 KLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCI 87 K + S + SR +KGG S +S+D+R+ RSR+ S R+ S Sbjct: 325 KSLRQSRSRSR-SKGGS-------RSRSRSRSKSKDKRKGRKRSREESRSRSRS------ 370 Query: 88 RNVTSPTRQHHVEREKDHSSS----RPSSPRPQKASPNGSISSAGNSSRN-SSQSSSDGS 142 R+ + +R+ +R+ SS + + R Q SP+ S+S +++ SSQ G Sbjct: 371 RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430 Query: 143 CKTAG 147 + AG Sbjct: 431 SENAG 435 Score = 30.8 bits (68), Expect = 2.8 Identities = 28/125 (22%), Positives = 47/125 (37%), Gaps = 4/125 (3%) Query: 26 PRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTP 85 P + S + SR + V+ K E+S + RS RS+ S R+ S+ Sbjct: 291 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS 350 Query: 86 CIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSCKT 145 + R+ E + S SR S R +K S AG+S + + + ++ Sbjct: 351 KDKR---KGRKRSREESRSRSRSRSKSERSRKRGSKRD-SKAGSSKKKKKEDTDRSQSRS 406 Query: 146 AGEMV 150 V Sbjct: 407 PSRSV 411 >gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] Length = 320 Score = 42.7 bits (99), Expect = 7e-04 Identities = 42/138 (30%), Positives = 64/138 (46%), Gaps = 16/138 (11%) Query: 8 YDGNSSDPENWDRKL---HSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDR 64 Y+ ++S+ E+ ++K SR + HS +SSR S +S RSR R Sbjct: 183 YNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSR----------SSSPSSSRSRSRSRSR 232 Query: 65 RRSS--DRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNG 122 SS RSR SS ER+ S+ + R+ + R R++ +SSS S R +K S + Sbjct: 233 SSSSSQSRSRSSSRERSRSRGSKS-RSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSR 291 Query: 123 SISSAGNSSRNSSQSSSD 140 S SS R + S + Sbjct: 292 SSSSGDRKKRRTRSRSPE 309 Score = 35.4 bits (80), Expect = 0.11 Identities = 35/121 (28%), Positives = 51/121 (42%), Gaps = 16/121 (13%) Query: 39 IAKGGVDHTKMSLHGASGGHERSRDRRRSS-----------DRSRDSSHERTESQLTPCI 87 ++K +D ++ + RSR + RSS SR S R+ S + Sbjct: 180 LSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS 239 Query: 88 RNVTSPTRQHHVEREKDHSSSR----PSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSC 143 R+ +S + K SSSR SSPR + S + S S N R+ S+SSS G Sbjct: 240 RSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSS-SPERNRKRSRSRSSSSGDR 298 Query: 144 K 144 K Sbjct: 299 K 299 >gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] Length = 344 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 9/86 (10%) Query: 55 SGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPR 114 SG RSR RRRS RSR SS R+ S S +R R K S SR + Sbjct: 192 SGSRSRSRSRRRSRSRSRRSSRSRSRS---------ISKSRSRSRSRSKGRSRSRSKGRK 242 Query: 115 PQKASPNGSISSAGNSSRNSSQSSSD 140 + S + S G+ S + S+S + Sbjct: 243 SRSKSKSKPKSDRGSHSHSRSRSKDE 268 Score = 32.3 bits (72), Expect = 0.96 Identities = 33/131 (25%), Positives = 48/131 (36%), Gaps = 15/131 (11%) Query: 20 RKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERT 79 R + +PR ++ S + SR ++ S RSR R S RSR S + Sbjct: 177 RLIEDKPRTSHRRSYSGSRSRS----RSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKG 232 Query: 80 ESQLTPCIRNVTSPTR----------QHHVEREKDHSSSRPSSPRPQKASPNGSISSAGN 129 S+ R S ++ H R KD S R + NG + Sbjct: 233 RSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGK-GDIKS 291 Query: 130 SSRNSSQSSSD 140 SR+ SQS S+ Sbjct: 292 KSRSRSQSRSN 302 Score = 30.8 bits (68), Expect = 2.8 Identities = 33/125 (26%), Positives = 48/125 (38%), Gaps = 5/125 (4%) Query: 20 RKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERT 79 R SR R + K S S +KG S + + R S SR S + Sbjct: 210 RSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEY 269 Query: 80 E-SQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSIS----SAGNSSRNS 134 E S+ R+ + + + S SR +SP P S S+S A + SR+ Sbjct: 270 EKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSR 329 Query: 135 SQSSS 139 S+S S Sbjct: 330 SRSKS 334 >gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] Length = 330 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/91 (35%), Positives = 39/91 (42%), Gaps = 10/91 (10%) Query: 25 RPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRS-SDRSRDSSHERTESQL 83 R R S +SSR +G K S +S ER+R R RS S S D RT S+ Sbjct: 248 RSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR- 306 Query: 84 TPCIRNVTSPTRQHHVEREKDHSSSRPSSPR 114 SP R+H HS SR SS + Sbjct: 307 --------SPERRHRSSSGSSHSGSRSSSKK 329 Score = 40.8 bits (94), Expect = 0.003 Identities = 40/147 (27%), Positives = 63/147 (42%), Gaps = 17/147 (11%) Query: 8 YDGNSSDPENWDRKL---HSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDR 64 Y+ ++S+ E+ ++K SR + HS +SSR + ++ S +SR R Sbjct: 183 YNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSR 242 Query: 65 RRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHH------VEREKDHSSSRPSSP----- 113 SS R R S + R +SP ++ + ER + S SR SS Sbjct: 243 --SSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK 300 Query: 114 -RPQKASPNGSISSAGNSSRNSSQSSS 139 R + SP S+ SS + S+SSS Sbjct: 301 RRTRSRSPERRHRSSSGSSHSGSRSSS 327 Score = 35.4 bits (80), Expect = 0.11 Identities = 35/121 (28%), Positives = 51/121 (42%), Gaps = 16/121 (13%) Query: 39 IAKGGVDHTKMSLHGASGGHERSRDRRRSS-----------DRSRDSSHERTESQLTPCI 87 ++K +D ++ + RSR + RSS SR S R+ S + Sbjct: 180 LSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS 239 Query: 88 RNVTSPTRQHHVEREKDHSSSR----PSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSC 143 R+ +S + K SSSR SSPR + S + S S N R+ S+SSS G Sbjct: 240 RSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSS-SPERNRKRSRSRSSSSGDR 298 Query: 144 K 144 K Sbjct: 299 K 299 >gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] Length = 352 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/114 (32%), Positives = 51/114 (44%), Gaps = 12/114 (10%) Query: 40 AKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRD-SSHERTESQLTPCIRNVTSPTRQHH 98 A+GG+ + + H SR R RS RSR S +R + RN ++ T Q Sbjct: 108 ARGGLSGPQGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGR 167 Query: 99 V--------EREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSCK 144 ER K + R R +S + S SS+ +SS +SS SSSDG K Sbjct: 168 KASTAPGAEERSKQKARRRT---RSSSSSSSSSSSSSSSSSSSSSSSSSDGRKK 218 >gi|52426743 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 41.2 bits (95), Expect = 0.002 Identities = 36/130 (27%), Positives = 53/130 (40%), Gaps = 14/130 (10%) Query: 19 DRKLHSRPRKLYKHSS-TSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHE 77 DR+ R R +HSS TS R DH + R R R RS DR R SH+ Sbjct: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKR--------SRSRERRRSRSRDRRRSRSHD 337 Query: 78 RTESQLTPCIRN-VTSPTRQH----HVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSR 132 R+E + R+ S +R H + +D R S + ++ S + S S Sbjct: 338 RSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSRE 397 Query: 133 NSSQSSSDGS 142 S+ ++ S Sbjct: 398 KQSEDTNTES 407 >gi|19923485 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 41.2 bits (95), Expect = 0.002 Identities = 36/130 (27%), Positives = 53/130 (40%), Gaps = 14/130 (10%) Query: 19 DRKLHSRPRKLYKHSS-TSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHE 77 DR+ R R +HSS TS R DH + R R R RS DR R SH+ Sbjct: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKR--------SRSRERRRSRSRDRRRSRSHD 337 Query: 78 RTESQLTPCIRN-VTSPTRQH----HVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSR 132 R+E + R+ S +R H + +D R S + ++ S + S S Sbjct: 338 RSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSRE 397 Query: 133 NSSQSSSDGS 142 S+ ++ S Sbjct: 398 KQSEDTNTES 407 >gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] Length = 1312 Score = 40.0 bits (92), Expect = 0.005 Identities = 40/172 (23%), Positives = 67/172 (38%), Gaps = 23/172 (13%) Query: 56 GGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRP 115 GG +DRRRS S SS S+ + + R +R++D S + P Sbjct: 743 GGKSSQKDRRRSGAASSSSSSREKGSRR----KALDGGDRDRDRDRDRDRDRSSKKARPP 798 Query: 116 QKASPNGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSERVTLIVDN 175 ++++P+ S S SSS SC +R ++ +V +++ Sbjct: 799 KESAPSSGPPPKPPVSSGSGSSSSSSSC---------------SSRKVKLQSKVAVLIRE 843 Query: 176 TRFVVDPSIFTAQPNT-MLGRMFGSGREHN--FTRPNEKGEYEVAEGI-GST 223 P+ A +G F RE F +P+E+ E+A+ GST Sbjct: 844 GVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGST 895 Score = 38.5 bits (88), Expect = 0.013 Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 14/115 (12%) Query: 18 WDRKLH-SRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSS---DRSRD 73 WD K H SR RK H+S+S+R ++ ++ RS DRRR RSR+ Sbjct: 550 WDSKKHRSRDRKPGSHASSSARRRSRSRSRSR-----STRRRSRSTDRRRGGSRRSRSRE 604 Query: 74 SSHERTES-QLTPCIRNVTSPTRQHHVEREKDHSSSRP----SSPRPQKASPNGS 123 R S P + +S R+ H + +D S+ S R +K S +GS Sbjct: 605 KRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGS 659 >gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] Length = 715 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/146 (26%), Positives = 59/146 (40%), Gaps = 14/146 (9%) Query: 3 GRPHPYDGNSSDPENWDRKLHSRPRKLYKHSST----SSRIAKGGVDHTKMSLHGASGGH 58 GR H + N S + S + ++ SS+ S R G + + S Sbjct: 350 GRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNK 409 Query: 59 ERSRDRRRSSDRSRDSSHERTESQLTPCIRN-----VTSPTRQHHVEREKDHSSSRPSSP 113 R R R RS ++RD S R+ ++ C R+ +R + +DHS SR Sbjct: 410 ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSR---- 465 Query: 114 RPQKASPNGSISSAGNSSRNSSQSSS 139 P KA + S S + + R+ SQ S Sbjct: 466 SPNKAR-DRSRSRSPSKERDHSQLGS 490 Score = 35.8 bits (81), Expect = 0.087 Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 33/146 (22%) Query: 24 SRPRKLYKHS-STSSRIAKGGVD---HTKMSLHGASGGHERSRDRRRS------SDRSRD 73 SRP+ HS S S R ++ G H+++ H H R+R R R S+ Sbjct: 276 SRPQS---HSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQS 332 Query: 74 SSHERTESQ---LTP-------CIRNVTSPTRQHH---VEREKDH---SSSRPSSPRPQK 117 SH + +SQ TP RN + H +E+DH SS R S R Q Sbjct: 333 RSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQS 392 Query: 118 ASPN----GSISSAGNSSRNSSQSSS 139 SPN S S + N +R+ S+S S Sbjct: 393 GSPNKQRDHSRSRSPNKARDRSRSRS 418 Score = 35.0 bits (79), Expect = 0.15 Identities = 36/147 (24%), Positives = 60/147 (40%), Gaps = 10/147 (6%) Query: 6 HPYDGNSSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRR 65 +P +S +++ + + K Y + SSR+ + + S H +SR R Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKS----YNQASTRSRPQSHSQSRSPR 288 Query: 66 RSSDRSRDSSHERTESQLTPCIRN---VTSPTRQHHVEREKDHSSSRP-SSPRPQKASPN 121 RS S+ +H R S RN S TR+ + + HS SR S + Q S Sbjct: 289 RSRSGSQKRTHSRVRSHSWK--RNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRT 346 Query: 122 GSISSAGNSSRNSSQSSSDGSCKTAGE 148 + N SRN S+ S +++ + Sbjct: 347 PRRGRSHNWSRNPSKERSHSHSRSSSK 373 Score = 33.1 bits (74), Expect = 0.57 Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 17/111 (15%) Query: 55 SGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHH-----VEREKDHSSSR 109 S ER R + RSS RD S R+ ++ + R S + H +E +HS SR Sbjct: 574 SPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSR 633 Query: 110 PSS----------PRPQ--KASPNGSISSAGNSSRNSSQSSSDGSCKTAGE 148 SS PR K SP + S + N + + + S S + + G+ Sbjct: 634 TSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQ 684 Score = 31.6 bits (70), Expect = 1.6 Identities = 32/125 (25%), Positives = 44/125 (35%), Gaps = 26/125 (20%) Query: 19 DRKLHSRPRKLYKHSSTSS----RIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDS 74 DR P K HS + S R +K H G + RD RRS S++ Sbjct: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507 Query: 75 SHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNS 134 ++ S +E+DH SR S Q+ S + N R+ Sbjct: 508 QCRQSRSS-----------------SKERDHRRSRSPSKERQRRQ-----SRSPNKERDR 545 Query: 135 SQSSS 139 SQS S Sbjct: 546 SQSRS 550 Score = 30.8 bits (68), Expect = 2.8 Identities = 27/114 (23%), Positives = 40/114 (35%), Gaps = 9/114 (7%) Query: 46 HTKMSLH--GASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREK 103 H + H G + G SR +RS R+ RT V +PT Q R K Sbjct: 112 HQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGK 171 Query: 104 DHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAK 157 + RP+ ++ S S N S+ S + + E+ AK Sbjct: 172 SYG-------RPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAK 218 Score = 29.3 bits (64), Expect = 8.2 Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 8/124 (6%) Query: 16 ENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSS 75 E D S RK+ + + T+MS S +R R +S +SR Sbjct: 229 EKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPR 288 Query: 76 HERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSS 135 R+ SQ + S R H +R +HS +R S R S G S + + S+ S Sbjct: 289 RSRSGSQ-----KRTHSRVRSHSWKR--NHSRAR-SRTRKGILSQMGRHSQSRSHSKGKS 340 Query: 136 QSSS 139 Q+ S Sbjct: 341 QNQS 344 Score = 29.3 bits (64), Expect = 8.2 Identities = 28/118 (23%), Positives = 47/118 (39%), Gaps = 11/118 (9%) Query: 23 HSRPRKLYKHSSTSS-RIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTES 81 HSR R K S S R + H++ G H +SR + SD S+ + + Sbjct: 593 HSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDW 652 Query: 82 QLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSS 139 + SPTR + + + + S+ SS P G S +S +++ S + Sbjct: 653 K--------RSPTRTSSLSQNR--TPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKA 700 >gi|60097902 filaggrin [Homo sapiens] Length = 4061 Score = 39.7 bits (91), Expect = 0.006 Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 5/139 (3%) Query: 31 KHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNV 90 +HS + A D ++ S G R + S S+DS ER R Sbjct: 1231 RHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSE---RLS 1287 Query: 91 TSPTRQHH-VEREKDHSSSR-PSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSCKTAGE 148 S +R HH RE+ SR P + +AS S S+ S + ++SSS G ++ E Sbjct: 1288 GSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHE 1347 Query: 149 MVFVYENAKEGARNIRTSE 167 + G+R+ ++++ Sbjct: 1348 QARSSPGERHGSRHQQSAD 1366 Score = 37.7 bits (86), Expect = 0.023 Identities = 43/164 (26%), Positives = 58/164 (35%), Gaps = 26/164 (15%) Query: 6 HPYDGNSSDPENWDRKLHSRPRKLY---------KHSSTSSRIAKGGVDHTKMSL--HGA 54 H SD S RK Y +HS + A D ++ SL G Sbjct: 2170 HTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQ 2229 Query: 55 SGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHH--VEREKDHSSSRPSS 112 S G SR R S + DS +S+ R S +R HH + + S P S Sbjct: 2230 SSGPRTSRPRGSSVSQDSDSEGHSEDSE-----RRSGSASRNHHGSAQEQSRDGSRHPRS 2284 Query: 113 PRPQKASPNGSISS--------AGNSSRNSSQSSSDGSCKTAGE 148 +A S S A NSS + SS + + +AGE Sbjct: 2285 HHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGE 2328 Score = 36.6 bits (83), Expect = 0.051 Identities = 31/139 (22%), Positives = 55/139 (39%), Gaps = 5/139 (3%) Query: 31 KHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNV 90 +HS + A D ++ S G RR+ S S+DS +E R Sbjct: 907 RHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSD---SEGHSEDSERWS 963 Query: 91 TSPTRQHH--VEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSCKTAGE 148 S +R H + + H S P S +A S S+ S +++SS G ++ E Sbjct: 964 GSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHE 1023 Query: 149 MVFVYENAKEGARNIRTSE 167 + G+R+ ++++ Sbjct: 1024 QARSSPGERHGSRHQQSAD 1042 Score = 32.7 bits (73), Expect = 0.74 Identities = 43/167 (25%), Positives = 66/167 (39%), Gaps = 26/167 (15%) Query: 3 GRPHPYDGN---SSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHE 59 G P P G S ++ DR HS HS T+S+ G G+ Sbjct: 2140 GHPGPSRGGRQGSHQEQSVDRSGHSGSH----HSHTTSQ----GRSDASRGQSGSRSASR 2191 Query: 60 RSRDRRRSSDRSRDS-SHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKA 118 ++ D+ +S D SR S SH S R+ Q SS P + RP+ + Sbjct: 2192 KTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQ----------SSGPRTSRPRGS 2241 Query: 119 SPNGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRT 165 S + S G+ S +S + S S G E +++G+R+ R+ Sbjct: 2242 SVSQDSDSEGH-SEDSERRSGSASRNHHGS---AQEQSRDGSRHPRS 2284 Score = 32.3 bits (72), Expect = 0.96 Identities = 36/153 (23%), Positives = 57/153 (37%), Gaps = 10/153 (6%) Query: 9 DGNSSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSS 68 +G+S D E HS H S + G AS GH R+ + Sbjct: 304 EGHSEDSER-----HSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGT 358 Query: 69 DRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAG 128 + SS +T S + +SP +H ++ SSR S+ +AS ++S G Sbjct: 359 RHAETSSRGQTASSHE---QARSSPGERHGSGHQQSADSSRHSATGRGQAS--SAVSDRG 413 Query: 129 NSSRNSSQSSSDGSCKTAGEMVFVYENAKEGAR 161 + + SQ+S + V + K G R Sbjct: 414 HRGSSGSQASDSEGHSENSDTQSVSGHGKAGLR 446 Score = 32.0 bits (71), Expect = 1.3 Identities = 31/131 (23%), Positives = 46/131 (35%), Gaps = 1/131 (0%) Query: 12 SSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRS 71 SS ++ D + HS + + S++ + + S H S HE S+D S Sbjct: 1916 SSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSH-HEDRAGHGHSADSS 1974 Query: 72 RDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSS 131 R S TES + R ER H + + +G SSA S Sbjct: 1975 RQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDS 2034 Query: 132 RNSSQSSSDGS 142 + S S S Sbjct: 2035 GHRGYSGSQAS 2045 Score = 31.2 bits (69), Expect = 2.1 Identities = 40/139 (28%), Positives = 54/139 (38%), Gaps = 19/139 (13%) Query: 12 SSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRR---SS 68 S ++ DR HS HS T+S+ G D + HG SG SR R+ S Sbjct: 1179 SHHEQSVDRSGHSGSH----HSHTTSQ---GRSDAS----HGQSGSRSASRQTRKDKQSG 1227 Query: 69 DRSRDS-SHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSA 127 D SR S S + R+ Q R H S S + + S + Sbjct: 1228 DGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLS 1287 Query: 128 GNSSRN----SSQSSSDGS 142 G++SRN S + S DGS Sbjct: 1288 GSASRNHHGSSREQSRDGS 1306 Score = 31.2 bits (69), Expect = 2.1 Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 11/137 (8%) Query: 31 KHSSTSSRIAKGGVDHTKMSL--HGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIR 88 +HS + A D ++ S G S G SR++ S + DS +S+ R Sbjct: 1879 RHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSE-----R 1933 Query: 89 NVTSPTRQH---HVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSCKT 145 S +R H E+ +D S P S +A S S+ S ++SSS G + Sbjct: 1934 WSGSASRNHLGSAWEQSRD-GSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAAS 1992 Query: 146 AGEMVFVYENAKEGARN 162 + E + G+ + Sbjct: 1993 SHEQARSSAGERHGSHH 2009 Score = 31.2 bits (69), Expect = 2.1 Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 4/116 (3%) Query: 31 KHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHER----TESQLTPC 86 +HS + A D ++ S G R RR+ S S+DS E +E + Sbjct: 3824 RHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESA 3883 Query: 87 IRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGS 142 RN +R+ + + SS + ++SP S SS + S S D + Sbjct: 3884 SRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSA 3939 Score = 30.8 bits (68), Expect = 2.8 Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 37/151 (24%) Query: 45 DHTKMSLHGASGGHERSRD---RRRSSDRS--------RDSSHERTESQ---LTPCIRNV 90 D +S HG +G H++S R RS + S + S+HE++ES P R Sbjct: 2703 DTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRG- 2761 Query: 91 TSPTRQHHVEREKDHSSSR---------PSSPR--PQKASPNGSISSAGNSSRNSSQSSS 139 +R + HS+S+ P S R Q S+ S+G+S + S ++S Sbjct: 2762 RQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTS 2821 Query: 140 DGSCKTAGEMVFVYENAKEGARNIRTSERVT 170 G +A G R++ R T Sbjct: 2822 QGR-----------SDASRGQSGSRSASRTT 2841 Score = 30.8 bits (68), Expect = 2.8 Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 37/151 (24%) Query: 45 DHTKMSLHGASGGHERSRD---RRRSSDRS--------RDSSHERTESQ---LTPCIRNV 90 D +S HG +G H++S R RS + S + S+HE++ES P R Sbjct: 3027 DTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRG- 3085 Query: 91 TSPTRQHHVEREKDHSSSR---------PSSPR--PQKASPNGSISSAGNSSRNSSQSSS 139 +R + HS+S+ P S R Q S+ S+G+S + S ++S Sbjct: 3086 RQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTS 3145 Query: 140 DGSCKTAGEMVFVYENAKEGARNIRTSERVT 170 G +A G R++ R T Sbjct: 3146 QGR-----------SDASRGQSGSRSASRTT 3165 Score = 30.8 bits (68), Expect = 2.8 Identities = 40/132 (30%), Positives = 52/132 (39%), Gaps = 19/132 (14%) Query: 19 DRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRR---RSSDRSRDS- 74 DR HS HS T+S+ G D + HG SG SR+ R +S D SR S Sbjct: 3779 DRSGHSGSH----HSHTTSQ---GRSDAS----HGQSGSRSASRETRNEEQSGDGSRHSG 3827 Query: 75 SHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRN- 133 S S R+ S + R S S +A P S + ++SRN Sbjct: 3828 SRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNH 3887 Query: 134 ---SSQSSSDGS 142 S + S DGS Sbjct: 3888 HGSSREQSRDGS 3899 Score = 30.0 bits (66), Expect = 4.8 Identities = 43/172 (25%), Positives = 62/172 (36%), Gaps = 27/172 (15%) Query: 10 GNSSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSD 69 G+S D E W H ++ ++ G H + S H GH S +D Sbjct: 629 GHSEDSERWSGSASRN------HHGSAQEQSRDGSRHPR-SHHEDRAGHGHS------AD 675 Query: 70 RSRDSSHERTES----QLTPCIRNVTSPTRQHHVEREKDHS--SSRPSSPRPQKASP--- 120 SR S T++ Q S + H R + S SSR S +AS Sbjct: 676 SSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVR 735 Query: 121 ----NGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSER 168 GS S S S+ S S G+ ++ +E AR+ R+ ER Sbjct: 736 DSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARD-RSGER 786 Score = 29.6 bits (65), Expect = 6.3 Identities = 30/105 (28%), Positives = 41/105 (39%), Gaps = 18/105 (17%) Query: 45 DHTKMSLHGASGGHERSRDRR------RSSDRSRD-----SSHERTESQLTPCIRNVTSP 93 D +S HG +G H++S SS RSR SSHE++ES T+P Sbjct: 1406 DTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSES-----THGQTAP 1460 Query: 94 TRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSS 138 + + H +R SS +I SSR Q S Sbjct: 1461 STGG--RQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGS 1503 Score = 29.6 bits (65), Expect = 6.3 Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 11/117 (9%) Query: 45 DHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKD 104 D + S + H SR++ R R SSH T S + S T + H Sbjct: 3875 DSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEH-----G 3929 Query: 105 HSSSRPSSPRPQKASPNGSISSAGNSSRNSS-QSSSDGSCKTAGEMVFVYENAKEGA 160 H SS Q ++ + I S G+ +SS S+G+ + G+ V+ + G+ Sbjct: 3930 HFSS-----LSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGS 3981 Score = 29.3 bits (64), Expect = 8.2 Identities = 26/109 (23%), Positives = 40/109 (36%), Gaps = 3/109 (2%) Query: 63 DRRRSSDRSRDSSHERTESQLT---PCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKAS 119 +R RSSD S R+ + T P + T R V +++D S R ++ Sbjct: 258 ERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSA 317 Query: 120 PNGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSER 168 SA SR+ S+ A + + G R+ TS R Sbjct: 318 SRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSR 366 >gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens] Length = 272 Score = 39.7 bits (91), Expect = 0.006 Identities = 31/86 (36%), Positives = 38/86 (44%), Gaps = 14/86 (16%) Query: 55 SGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPR 114 S RSR R RSS RSR S R+ R S +R R + S S SP Sbjct: 184 SRSRSRSRSRTRSSSRSRSRSRSRS--------RKSYSRSRSRSRSRSRSKSRSVSRSPV 235 Query: 115 PQKASPNGSISSAGNSSRNSSQSSSD 140 P+K+ GS SSR+ S +S D Sbjct: 236 PEKSQKRGS------SSRSKSPASVD 255 Score = 33.9 bits (76), Expect = 0.33 Identities = 35/123 (28%), Positives = 52/123 (42%), Gaps = 17/123 (13%) Query: 20 RKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERT 79 ++++ R KL + S SR T+ S S RSR +S RSR S R+ Sbjct: 167 KEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSR---KSYSRSRSRSRSRS 223 Query: 80 ESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSS 139 S+ R SP + + +K SSSR SP S+ + SR+ S+S Sbjct: 224 RSKSRSVSR---SPVPE---KSQKRGSSSRSKSP--------ASVDRQRSRSRSRSRSVD 269 Query: 140 DGS 142 G+ Sbjct: 270 SGN 272 >gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens] Length = 272 Score = 39.7 bits (91), Expect = 0.006 Identities = 31/86 (36%), Positives = 38/86 (44%), Gaps = 14/86 (16%) Query: 55 SGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPR 114 S RSR R RSS RSR S R+ R S +R R + S S SP Sbjct: 184 SRSRSRSRSRTRSSSRSRSRSRSRS--------RKSYSRSRSRSRSRSRSKSRSVSRSPV 235 Query: 115 PQKASPNGSISSAGNSSRNSSQSSSD 140 P+K+ GS SSR+ S +S D Sbjct: 236 PEKSQKRGS------SSRSKSPASVD 255 Score = 33.9 bits (76), Expect = 0.33 Identities = 35/123 (28%), Positives = 52/123 (42%), Gaps = 17/123 (13%) Query: 20 RKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERT 79 ++++ R KL + S SR T+ S S RSR +S RSR S R+ Sbjct: 167 KEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSR---KSYSRSRSRSRSRS 223 Query: 80 ESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSS 139 S+ R SP + + +K SSSR SP S+ + SR+ S+S Sbjct: 224 RSKSRSVSR---SPVPE---KSQKRGSSSRSKSP--------ASVDRQRSRSRSRSRSVD 269 Query: 140 DGS 142 G+ Sbjct: 270 SGN 272 >gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens] Length = 360 Score = 39.7 bits (91), Expect = 0.006 Identities = 35/119 (29%), Positives = 50/119 (42%), Gaps = 14/119 (11%) Query: 40 AKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRD-SSHERTESQLTPCIRNVTSPTRQHH 98 A+GG+ + + H SR R RS RSR S +R + RN ++ T Q Sbjct: 108 ARGGLSGPQGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGR 167 Query: 99 VEREKDHSSSRPSS-------------PRPQKASPNGSISSAGNSSRNSSQSSSDGSCK 144 + + PS R +S + S SS+ +SS +SS SSSDG K Sbjct: 168 KASTAPGAEASPSPCITERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKK 226 >gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform 2 [Homo sapiens] Length = 715 Score = 39.3 bits (90), Expect = 0.008 Identities = 50/207 (24%), Positives = 75/207 (36%), Gaps = 29/207 (14%) Query: 32 HSSTSSRIAKGGVDHTKMSLHGAS----------GGHERSRDRRRS---------SDRSR 72 HS GG+ H M + + RS +RRS S+ Sbjct: 504 HSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQG 563 Query: 73 DSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPR--PQKASPNGSISSAGNS 130 DS + TP +P H + K +SS PSSP P K P + G + Sbjct: 564 DSRARCDSTSSTP-----KTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRA 618 Query: 131 SRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTS--ERVTLIVDNTRFVVDPSIFTAQ 188 SS S+S S TAGE + E G++ TS ++ + + PS+ A Sbjct: 619 ISRSSSSTSSVS-STAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAA 677 Query: 189 PNTMLGRMFGSGREHNFTRPNEKGEYE 215 ++ R + N R N K ++ Sbjct: 678 TPIIMSRSPTDAKSRNSPRSNLKFRFD 704 >gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform 1 [Homo sapiens] Length = 730 Score = 39.3 bits (90), Expect = 0.008 Identities = 50/207 (24%), Positives = 75/207 (36%), Gaps = 29/207 (14%) Query: 32 HSSTSSRIAKGGVDHTKMSLHGAS----------GGHERSRDRRRS---------SDRSR 72 HS GG+ H M + + RS +RRS S+ Sbjct: 519 HSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQG 578 Query: 73 DSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPR--PQKASPNGSISSAGNS 130 DS + TP +P H + K +SS PSSP P K P + G + Sbjct: 579 DSRARCDSTSSTP-----KTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRA 633 Query: 131 SRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTS--ERVTLIVDNTRFVVDPSIFTAQ 188 SS S+S S TAGE + E G++ TS ++ + + PS+ A Sbjct: 634 ISRSSSSTSSVS-STAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAA 692 Query: 189 PNTMLGRMFGSGREHNFTRPNEKGEYE 215 ++ R + N R N K ++ Sbjct: 693 TPIIMSRSPTDAKSRNSPRSNLKFRFD 719 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 38.9 bits (89), Expect = 0.010 Identities = 37/126 (29%), Positives = 48/126 (38%), Gaps = 4/126 (3%) Query: 23 HSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQ 82 H R R + S S ++ D K S G RSRDR R +RSR R+ S+ Sbjct: 7 HYRKRSASRGRSGSRSRSRSPSD--KRSKRG-DDRRSRSRDRDRRRERSRSRDKRRSRSR 63 Query: 83 LTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGS 142 +R S R ER + S R S R + SS GN S+ + S Sbjct: 64 DRKRLRRSRSRERDRSRERRRSRSRDRRRS-RSRSRGRRSRSSSPGNKSKKTENRSRSKE 122 Query: 143 CKTAGE 148 GE Sbjct: 123 KTDGGE 128 Score = 32.7 bits (73), Expect = 0.74 Identities = 25/99 (25%), Positives = 38/99 (38%) Query: 19 DRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHER 78 DR+ SR R + S S + K S +RSR+RRRS R R S R Sbjct: 37 DRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSR 96 Query: 79 TESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQK 117 + + + + + R K+ + SS +K Sbjct: 97 SRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKK 135 >gi|50962882 G patch domain containing 8 [Homo sapiens] Length = 1502 Score = 38.9 bits (89), Expect = 0.010 Identities = 42/153 (27%), Positives = 64/153 (41%), Gaps = 15/153 (9%) Query: 4 RPHPYDGNSSDPENWDRKLH--SRPRKLYKHSSTSSRIAKGGVDHTKMSLHGA------- 54 +P P S P R+ S+ R L +S + +GG + HG Sbjct: 732 KPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQD-HGGRKHKGEL 790 Query: 55 --SGGHERSRDRR--RSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRP 110 S R+ +R RSS RS+ SS + + + SP+ Q+ E E++ S S Sbjct: 791 PPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPS-QYSEEEEEEDSGSEH 849 Query: 111 SSPRPQKASPNGSISSAGNSSRNSSQSSSDGSC 143 S R + + S S+ S +SS +SSD SC Sbjct: 850 SRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSC 882 Score = 35.0 bits (79), Expect = 0.15 Identities = 27/107 (25%), Positives = 40/107 (37%), Gaps = 6/107 (5%) Query: 31 KHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNV 90 KH S + + D++ S +R+R RS RSR SS R+ S + Sbjct: 920 KHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRS------KRR 973 Query: 91 TSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQS 137 + T H +R + +S R S R S G+ S S Sbjct: 974 SRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHS 1020 Score = 32.0 bits (71), Expect = 1.3 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 2/93 (2%) Query: 47 TKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHS 106 +K G S H++ + ++SS R + TE + + S R+ +R+K+ S Sbjct: 664 SKKERSGKSHRHKKKKKHKKSSKHKRKHKAD-TEEKSSKAESGEKSKKRKKR-KRKKNKS 721 Query: 107 SSRPSSPRPQKASPNGSISSAGNSSRNSSQSSS 139 S+ S R K P GS S A R +Q S Sbjct: 722 SAPADSERGPKPEPPGSGSPAPPRRRRRAQDDS 754 Score = 31.6 bits (70), Expect = 1.6 Identities = 38/160 (23%), Positives = 54/160 (33%), Gaps = 18/160 (11%) Query: 4 RPHPYDGNSSDPENWDRKLHSRPRKLYKHSS---------TSSRIAKGGVDHTKMSLHGA 54 R H + SD ++ H R Y S + SR + ++ Sbjct: 902 RRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSR 961 Query: 55 SGGHERSRDRRRSSD-------RSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSS 107 S RSR +RRS RSR S +R+ S +P R+ + H E+ HS Sbjct: 962 SSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSG 1021 Query: 108 SRP--SSPRPQKASPNGSISSAGNSSRNSSQSSSDGSCKT 145 R S + SP+ S G D S T Sbjct: 1022 RRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKAT 1061 >gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] Length = 484 Score = 38.5 bits (88), Expect = 0.013 Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 12/119 (10%) Query: 20 RKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERT 79 R SR R + + +SSR H + H +SR RRRS R SH R Sbjct: 247 RHSRSRSRSRRRRTPSSSR-------HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRE 299 Query: 80 ESQLTPCIRNVTSPTRQHHVE-REKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQS 137 + + TS TR E +EK S + P S + S + S SR+ ++S Sbjct: 300 RGRRS----RSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRS 354 Score = 35.0 bits (79), Expect = 0.15 Identities = 34/127 (26%), Positives = 47/127 (37%), Gaps = 8/127 (6%) Query: 20 RKLHSRPRKLYKHSSTSSRIAKGGVDHTKMS------LHGASGGHERSRDRRRSSDRSRD 73 R+ HSR R S++ +R K K S A SR+RRR RS Sbjct: 293 RRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGT 352 Query: 74 SSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRN 133 S ++ S R+ SP R+H E++KD R R + S Sbjct: 353 RSPKKPRSPKRKLSRS-PSP-RRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRER 410 Query: 134 SSQSSSD 140 S+S D Sbjct: 411 KSESDKD 417 Score = 30.8 bits (68), Expect = 2.8 Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 12/124 (9%) Query: 20 RKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERT 79 R+ SR R+ HS + SR +K S ER R RS+ ++RD E Sbjct: 267 RRSRSRSRRR-SHSKSRSR------RRSKSPRRRRSHSRERGRR-SRSTSKTRDKKKEDK 318 Query: 80 ESQ--LTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQK-ASPNGSISSAGNSSRNSSQ 136 E + TP ++ ++ R RE+ SR + P+K SP +S + + R+ + Sbjct: 319 EKKRSKTP-PKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKE 377 Query: 137 SSSD 140 D Sbjct: 378 KKKD 381 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 38.1 bits (87), Expect = 0.018 Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 4/125 (3%) Query: 25 RPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLT 84 +P K + SS+SS + + S +S G S S + + +R S T Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP-T 2583 Query: 85 PCIRNVTS---PTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDG 141 P + P +R++ SSS SS +S + S SS+ +SS +SS SSS Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643 Query: 142 SCKTA 146 S ++ Sbjct: 2644 SSSSS 2648 Score = 33.5 bits (75), Expect = 0.43 Identities = 49/224 (21%), Positives = 85/224 (37%), Gaps = 34/224 (15%) Query: 9 DGNSSDPENWDRKLHS------RPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSR 62 DG+S DP+ R+ +P L + SS+S S ++ + Sbjct: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSR------------SPTPKQKKKKKKK 194 Query: 63 DRRRSS-------DRSRDSSHERTESQLTPCIRNVTSPT-RQHHVEREKDHSSSRPSSPR 114 DR R S +R + S ++ S+ R SPT + ++K SR ++P Sbjct: 195 DRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA 254 Query: 115 PQKASPNGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYE-----NAKEGARNIRTSERV 169 P+ + S S+ SS ++S+S S + + + G + SE Sbjct: 255 PKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPG 314 Query: 170 TLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGE 213 T +T+ P T QP++ +E + TRP+ E Sbjct: 315 T---TSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPE 355 Score = 33.1 bits (74), Expect = 0.57 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 7/89 (7%) Query: 54 ASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSP 113 A G RSR R S RSR + R + R S +R V R + HS + Sbjct: 664 ARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSL-VRRGRSHSRT----- 717 Query: 114 RPQKASPNGSISSAGNSSRNSSQSSSDGS 142 PQ+ +GS S N SR S + S S Sbjct: 718 -PQRRGRSGSSSERKNKSRTSQRRSRSNS 745 Score = 30.8 bits (68), Expect = 2.8 Identities = 23/91 (25%), Positives = 36/91 (39%) Query: 47 TKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHS 106 T +S + E S R RS +S + + + S+ +P T +R E Sbjct: 384 TPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKP 443 Query: 107 SSRPSSPRPQKASPNGSISSAGNSSRNSSQS 137 + P S R +SP S G + R+ S S Sbjct: 444 APAPGSHREISSSPTSKNRSHGRAKRDKSHS 474 Score = 30.0 bits (66), Expect = 4.8 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 9/87 (10%) Query: 64 RRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHS--------SSRPSSPRP 115 RRRS R+ + R+ S+ P IR S +R + R++ S SR +PR Sbjct: 2003 RRRSRSRTSPVTRRRSRSRTPPAIRR-RSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRT 2061 Query: 116 QKASPNGSISSAGNSSRNSSQSSSDGS 142 + + + S R++S SSSD S Sbjct: 2062 ARGKRSLTRSPPAIRRRSASGSSSDRS 2088 Score = 29.3 bits (64), Expect = 8.2 Identities = 39/141 (27%), Positives = 55/141 (39%), Gaps = 25/141 (17%) Query: 10 GNSSDPEN--WDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKM--------SLHGASGGHE 59 G S P+ W R +++ R SR A+ G H++ S A G Sbjct: 532 GRSRSPQRPGWSRSRNTQRRG-------RSRSARRGRSHSRSPATRGRSRSRTPARRGRS 584 Query: 60 RSRDRRRSSDRSRDSSHERTESQLTPCIRNVT---SPTRQHHVEREKDHSSSRPSSPRPQ 116 RSR R RSR + R+ S+ TP R + +P R+ R SR SP Sbjct: 585 RSRTPARRRSRSRTPTRRRSRSR-TPARRGRSRSRTPARRRSRTRSPVRRRSRSRSP--- 640 Query: 117 KASPNGSISSAGNSSRNSSQS 137 A +G S + R S+S Sbjct: 641 -ARRSGRSRSRTPARRGRSRS 660 >gi|113415504 PREDICTED: similar to ribonucleic acid binding protein S1 [Homo sapiens] Length = 305 Score = 37.7 bits (86), Expect = 0.023 Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 8/101 (7%) Query: 48 KMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKD--- 104 K SL G +++S R S + +D S E+++ + + T + + R+K Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKD--KGATKESSEKDRGRDKTRKR 65 Query: 105 HSSSRPSS---PRPQKASPNGSISSAGNSSRNSSQSSSDGS 142 HS+S SS R S +GS +S G+SS +SS S+S S Sbjct: 66 HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRS 106 Score = 37.4 bits (85), Expect = 0.030 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Query: 59 ERSRDRRRSSDRSRDSSHE---RTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRP 115 E+S+DR + +++SS + R +++ + +S TR SS+ S Sbjct: 37 EKSKDRSKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSG 96 Query: 116 QKASPNGSISSAGNSSRNSSQSSSDGS 142 +S S S + ++SR+SS SSS GS Sbjct: 97 SSSSSASSRSGSSSTSRSSSSSSSSGS 123 Score = 33.9 bits (76), Expect = 0.33 Identities = 33/119 (27%), Positives = 46/119 (38%), Gaps = 15/119 (12%) Query: 20 RKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERT 79 RK HS S SS + G + S G+S SR S+ RS SS Sbjct: 63 RKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS---- 118 Query: 80 ESQLTPCIRNVTSPTRQHHVEREKDHSSSRP-----SSPRPQKASPNGSISSAGNSSRN 133 S +P SP+R+ H R + S S+P + + SP + G +RN Sbjct: 119 SSSGSP------SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRN 171 >gi|169166499 PREDICTED: similar to ribonucleic acid binding protein S1 [Homo sapiens] Length = 305 Score = 37.7 bits (86), Expect = 0.023 Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 8/101 (7%) Query: 48 KMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKD--- 104 K SL G +++S R S + +D S E+++ + + T + + R+K Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKD--KGATKESSEKDRGRDKTRKR 65 Query: 105 HSSSRPSS---PRPQKASPNGSISSAGNSSRNSSQSSSDGS 142 HS+S SS R S +GS +S G+SS +SS S+S S Sbjct: 66 HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRS 106 Score = 37.4 bits (85), Expect = 0.030 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Query: 59 ERSRDRRRSSDRSRDSSHE---RTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRP 115 E+S+DR + +++SS + R +++ + +S TR SS+ S Sbjct: 37 EKSKDRSKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSG 96 Query: 116 QKASPNGSISSAGNSSRNSSQSSSDGS 142 +S S S + ++SR+SS SSS GS Sbjct: 97 SSSSSASSRSGSSSTSRSSSSSSSSGS 123 Score = 33.9 bits (76), Expect = 0.33 Identities = 33/119 (27%), Positives = 46/119 (38%), Gaps = 15/119 (12%) Query: 20 RKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERT 79 RK HS S SS + G + S G+S SR S+ RS SS Sbjct: 63 RKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS---- 118 Query: 80 ESQLTPCIRNVTSPTRQHHVEREKDHSSSRP-----SSPRPQKASPNGSISSAGNSSRN 133 S +P SP+R+ H R + S S+P + + SP + G +RN Sbjct: 119 SSSGSP------SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRN 171 >gi|113415498 PREDICTED: similar to ribonucleic acid binding protein S1 [Homo sapiens] Length = 305 Score = 37.7 bits (86), Expect = 0.023 Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 8/101 (7%) Query: 48 KMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKD--- 104 K SL G +++S R S + +D S E+++ + + T + + R+K Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKD--KGATKESSEKDRGRDKTRKR 65 Query: 105 HSSSRPSS---PRPQKASPNGSISSAGNSSRNSSQSSSDGS 142 HS+S SS R S +GS +S G+SS +SS S+S S Sbjct: 66 HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRS 106 Score = 37.4 bits (85), Expect = 0.030 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Query: 59 ERSRDRRRSSDRSRDSSHE---RTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRP 115 E+S+DR + +++SS + R +++ + +S TR SS+ S Sbjct: 37 EKSKDRSKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSG 96 Query: 116 QKASPNGSISSAGNSSRNSSQSSSDGS 142 +S S S + ++SR+SS SSS GS Sbjct: 97 SSSSSASSRSGSSSTSRSSSSSSSSGS 123 Score = 33.9 bits (76), Expect = 0.33 Identities = 33/119 (27%), Positives = 46/119 (38%), Gaps = 15/119 (12%) Query: 20 RKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERT 79 RK HS S SS + G + S G+S SR S+ RS SS Sbjct: 63 RKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS---- 118 Query: 80 ESQLTPCIRNVTSPTRQHHVEREKDHSSSRP-----SSPRPQKASPNGSISSAGNSSRN 133 S +P SP+R+ H R + S S+P + + SP + G +RN Sbjct: 119 SSSGSP------SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRN 171 >gi|88973230 PREDICTED: similar to ribonucleic acid binding protein S1 isoform 3 [Homo sapiens] Length = 305 Score = 37.7 bits (86), Expect = 0.023 Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 8/101 (7%) Query: 48 KMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKD--- 104 K SL G +++S R S + +D S E+++ + + T + + R+K Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKD--KGATKESSEKDRGRDKTRKR 65 Query: 105 HSSSRPSS---PRPQKASPNGSISSAGNSSRNSSQSSSDGS 142 HS+S SS R S +GS +S G+SS +SS S+S S Sbjct: 66 HSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRS 106 Score = 37.4 bits (85), Expect = 0.030 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Query: 59 ERSRDRRRSSDRSRDSSHE---RTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRP 115 E+S+DR + +++SS + R +++ + +S TR SS+ S Sbjct: 37 EKSKDRSKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSG 96 Query: 116 QKASPNGSISSAGNSSRNSSQSSSDGS 142 +S S S + ++SR+SS SSS GS Sbjct: 97 SSSSSASSRSGSSSTSRSSSSSSSSGS 123 Score = 33.9 bits (76), Expect = 0.33 Identities = 33/119 (27%), Positives = 46/119 (38%), Gaps = 15/119 (12%) Query: 20 RKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERT 79 RK HS S SS + G + S G+S SR S+ RS SS Sbjct: 63 RKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS---- 118 Query: 80 ESQLTPCIRNVTSPTRQHHVEREKDHSSSRP-----SSPRPQKASPNGSISSAGNSSRN 133 S +P SP+R+ H R + S S+P + + SP + G +RN Sbjct: 119 SSSGSP------SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRN 171 >gi|58331242 formin homology 2 domain containing 3 [Homo sapiens] Length = 1439 Score = 37.4 bits (85), Expect = 0.030 Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 8/89 (8%) Query: 45 DHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTS-PTRQHHVEREK 103 D + S+ + GG R DRRRS S S + +PC ++ S Q REK Sbjct: 340 DRRRASVCSSGGGEHRGLDRRRSRRHSVQSIKSTLSAPTSPCSQSAPSFKPNQVRDLREK 399 Query: 104 -------DHSSSRPSSPRPQKASPNGSIS 125 + SSRPSS +P S+S Sbjct: 400 YSNFGNNSYHSSRPSSGSSVPTTPTSSVS 428 >gi|169166609 PREDICTED: similar to ribonucleic acid binding protein S1 isoform 6 [Homo sapiens] Length = 305 Score = 37.4 bits (85), Expect = 0.030 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Query: 59 ERSRDRRRSSDRSRDSSHE---RTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRP 115 E+S+DR + +++SS + R +++ + +S TR SS+ S Sbjct: 37 EKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSG 96 Query: 116 QKASPNGSISSAGNSSRNSSQSSSDGS 142 +S S S + ++SR+SS SSS GS Sbjct: 97 SSSSSASSRSGSSSTSRSSSSSSSSGS 123 Score = 35.8 bits (81), Expect = 0.087 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 8/98 (8%) Query: 45 DHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKD 104 ++ K S S + R +S DRS+D + S+ R +R Sbjct: 17 NNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSE--------KDRGRDKTRKRRSA 68 Query: 105 HSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGS 142 S S + R S +GS +S G+SS +SS S+S S Sbjct: 69 SSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRS 106 Score = 33.1 bits (74), Expect = 0.57 Identities = 33/127 (25%), Positives = 48/127 (37%), Gaps = 12/127 (9%) Query: 12 SSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRS 71 SS+ + K R SST SR + + S G+S G S RS S Sbjct: 52 SSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTST-GSSSGSSSSSASSRSGSSS 110 Query: 72 RDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRP-----SSPRPQKASPNGSISS 126 S + S +P SP+R+ H R + S S+P + + SP + Sbjct: 111 TSRSSSSSSSSGSP------SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVH 164 Query: 127 AGNSSRN 133 G +RN Sbjct: 165 IGRLTRN 171 Score = 31.6 bits (70), Expect = 1.6 Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 13/112 (11%) Query: 48 KMSLHGASGGHERSRDRRRSSDRSRDSSHERTE--SQLTPCIRNVTSPTRQHHVEREKDH 105 K SL G +++S R S + +D S E+++ S+ + + R R++ Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRS 67 Query: 106 SSSRPSSPRPQKASPNGS-----------ISSAGNSSRNSSQSSSDGSCKTA 146 +SS SS R + +S + S SS+ SSR+ S S+S S ++ Sbjct: 68 ASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSS 119 >gi|113415994 PREDICTED: similar to ribonucleic acid binding protein S1 isoform 2 [Homo sapiens] Length = 305 Score = 37.4 bits (85), Expect = 0.030 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Query: 59 ERSRDRRRSSDRSRDSSHE---RTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRP 115 E+S+DR + +++SS + R +++ + +S TR SS+ S Sbjct: 37 EKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSG 96 Query: 116 QKASPNGSISSAGNSSRNSSQSSSDGS 142 +S S S + ++SR+SS SSS GS Sbjct: 97 SSSSSASSRSGSSSTSRSSSSSSSSGS 123 Score = 35.8 bits (81), Expect = 0.087 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 8/98 (8%) Query: 45 DHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKD 104 ++ K S S + R +S DRS+D + S+ R +R Sbjct: 17 NNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSE--------KDRGRDKTRKRRSA 68 Query: 105 HSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGS 142 S S + R S +GS +S G+SS +SS S+S S Sbjct: 69 SSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRS 106 Score = 33.1 bits (74), Expect = 0.57 Identities = 33/127 (25%), Positives = 48/127 (37%), Gaps = 12/127 (9%) Query: 12 SSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRS 71 SS+ + K R SST SR + + S G+S G S RS S Sbjct: 52 SSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTST-GSSSGSSSSSASSRSGSSS 110 Query: 72 RDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRP-----SSPRPQKASPNGSISS 126 S + S +P SP+R+ H R + S S+P + + SP + Sbjct: 111 TSRSSSSSSSSGSP------SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVH 164 Query: 127 AGNSSRN 133 G +RN Sbjct: 165 IGRLTRN 171 Score = 31.6 bits (70), Expect = 1.6 Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 13/112 (11%) Query: 48 KMSLHGASGGHERSRDRRRSSDRSRDSSHERTE--SQLTPCIRNVTSPTRQHHVEREKDH 105 K SL G +++S R S + +D S E+++ S+ + + R R++ Sbjct: 8 KKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRS 67 Query: 106 SSSRPSSPRPQKASPNGS-----------ISSAGNSSRNSSQSSSDGSCKTA 146 +SS SS R + +S + S SS+ SSR+ S S+S S ++ Sbjct: 68 ASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSS 119 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,880,575 Number of Sequences: 37866 Number of extensions: 925615 Number of successful extensions: 4665 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 170 Number of HSP's that attempted gapping in prelim test: 3578 Number of HSP's gapped (non-prelim): 834 length of query: 475 length of database: 18,247,518 effective HSP length: 106 effective length of query: 369 effective length of database: 14,233,722 effective search space: 5252243418 effective search space used: 5252243418 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.