Guide to the Human Genome
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Search of human proteins with 122937335

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937335 F-box protein 46 [Homo sapiens]
         (603 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937335 F-box protein 46 [Homo sapiens]                         1276   0.0  
gi|195222730 F-box only protein 34 [Homo sapiens]                     288   1e-77
gi|40807493 F-box only protein 34 [Homo sapiens]                      288   1e-77
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      64   3e-10
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    57   4e-08
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]    55   2e-07
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    52   2e-06
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    52   2e-06
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    52   2e-06
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             49   1e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         49   1e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    48   3e-05
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         48   3e-05
gi|153070260 myristoylated alanine-rich protein kinase C substra...    47   7e-05
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                46   1e-04
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       45   1e-04
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    45   2e-04
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      45   3e-04
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      44   3e-04
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    44   4e-04
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    44   4e-04
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    44   4e-04
gi|208022661 hypothetical protein LOC57701 [Homo sapiens]              43   7e-04
gi|156416026 zinc finger protein 219 [Homo sapiens]                    43   7e-04
gi|156415998 zinc finger protein 219 [Homo sapiens]                    43   7e-04
gi|156415996 zinc finger protein 219 [Homo sapiens]                    43   7e-04
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    43   0.001
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    43   0.001
gi|39812378 RAN binding protein 9 [Homo sapiens]                       42   0.001
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    42   0.001

>gi|122937335 F-box protein 46 [Homo sapiens]
          Length = 603

 Score = 1276 bits (3303), Expect = 0.0
 Identities = 603/603 (100%), Positives = 603/603 (100%)

Query: 1   MDRGSLLPFQLWCPRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPAL 60
           MDRGSLLPFQLWCPRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPAL
Sbjct: 1   MDRGSLLPFQLWCPRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPAL 60

Query: 61  ATEVPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKV 120
           ATEVPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKV
Sbjct: 61  ATEVPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKV 120

Query: 121 KGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVE 180
           KGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVE
Sbjct: 121 KGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVE 180

Query: 181 QRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDS 240
           QRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDS
Sbjct: 181 QRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDS 240

Query: 241 PPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARA 300
           PPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARA
Sbjct: 241 PPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARA 300

Query: 301 KDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCG 360
           KDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCG
Sbjct: 301 KDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCG 360

Query: 361 ASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPP 420
           ASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPP
Sbjct: 361 ASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPP 420

Query: 421 EPPPADSPATAPGPDDAEGTADTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHV 480
           EPPPADSPATAPGPDDAEGTADTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHV
Sbjct: 421 EPPPADSPATAPGPDDAEGTADTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHV 480

Query: 481 LVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKG 540
           LVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKG
Sbjct: 481 LVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKG 540

Query: 541 DVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGPGGGRAGRE 600
           DVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGPGGGRAGRE
Sbjct: 541 DVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGPGGGRAGRE 600

Query: 601 EGR 603
           EGR
Sbjct: 601 EGR 603


>gi|195222730 F-box only protein 34 [Homo sapiens]
          Length = 711

 Score =  288 bits (737), Expect = 1e-77
 Identities = 216/670 (32%), Positives = 302/670 (45%), Gaps = 133/670 (19%)

Query: 28  PSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLLD 87
           PSA+L  ++  +P G   P+   + S  +P   +  V   + AP  +     +EG   LD
Sbjct: 49  PSASLGKASSRKPFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGP--LD 106

Query: 88  TWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAP--- 144
            W V+KPGNTKEK+AFF +HQC   +R  SMK+K  W  D    KRR++  D  KA    
Sbjct: 107 IWAVVKPGNTKEKIAFFASHQCS--NRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQV 164

Query: 145 ------------PDPGGREGPPAAEEGPASAGEDVDL---LSVAEMVALVEQRAALALQS 189
                       P+P        +    + +G+ V     LSV +MVA +EQRA+  L S
Sbjct: 165 ERMREVNSRCYQPEPFACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLAS 224

Query: 190 YPRPTTPAPVV--FVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGL- 246
             +  T +P +  F    +G PA    SE  S  G C    E       +  S P + L 
Sbjct: 225 CSKNCTNSPAIVRFSGQSRGVPAV---SESYSAPGACEEPTERGNLEVGEPQSEPVRVLD 281

Query: 247 ----------RKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGP 296
                     +++ +  PG      +FR + GR   A  +    G   +     P +   
Sbjct: 282 MVAKLESECLKRQGQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDT--- 338

Query: 297 GARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPP---- 352
                      +  + S S D  PS  +    + D+A +G S      +D PP P     
Sbjct: 339 ----------QVNPVGSVSVDCGPSRADRCSPKEDQAWDGAS------QDCPPLPAGVSF 382

Query: 353 -------PPPARDCGASGFHVDVVVTGVVDECIFFGKDGTK------------------- 386
                   P ++    +    DV +T  +    F     ++                   
Sbjct: 383 HIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHTYSQASELPTDAVDCMSRELVSL 442

Query: 387 -----NVKEETVCLTVSPE-------------EPPPPGQLFFL---------QNRGPDGP 419
                + ++E++C++++               E P PG LFFL                 
Sbjct: 443 TSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTT 502

Query: 420 PEPPPADSPATAPGPDDAE--------------GTADTSLCRLY-----RHVSHDFLEIR 460
            E   A     A G D A                + +++L  L      + VSHDFLE R
Sbjct: 503 KESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVESTLPVLEASSWKKQVSHDFLETR 562

Query: 461 FKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWS 520
           FKIQ+LLEP+QYM  LP H++VKIF  LPT++L ALKCTC +FK IIE + +R  DSRW 
Sbjct: 563 FKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYYNIRPADSRWV 622

Query: 521 RDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGL 580
           RDP YR+DPCKQC+K+Y KGDVSLCRWHPKPY   LPYG  YWMCC R+ +  PGC+LGL
Sbjct: 623 RDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGFPGCKLGL 682

Query: 581 HDNNWVLPCN 590
           HDN+WV  C+
Sbjct: 683 HDNHWVPACH 692


>gi|40807493 F-box only protein 34 [Homo sapiens]
          Length = 711

 Score =  288 bits (737), Expect = 1e-77
 Identities = 216/670 (32%), Positives = 302/670 (45%), Gaps = 133/670 (19%)

Query: 28  PSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLLD 87
           PSA+L  ++  +P G   P+   + S  +P   +  V   + AP  +     +EG   LD
Sbjct: 49  PSASLGKASSRKPFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGP--LD 106

Query: 88  TWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAP--- 144
            W V+KPGNTKEK+AFF +HQC   +R  SMK+K  W  D    KRR++  D  KA    
Sbjct: 107 IWAVVKPGNTKEKIAFFASHQCS--NRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQV 164

Query: 145 ------------PDPGGREGPPAAEEGPASAGEDVDL---LSVAEMVALVEQRAALALQS 189
                       P+P        +    + +G+ V     LSV +MVA +EQRA+  L S
Sbjct: 165 ERMREVNSRCYQPEPFACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLAS 224

Query: 190 YPRPTTPAPVV--FVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGL- 246
             +  T +P +  F    +G PA    SE  S  G C    E       +  S P + L 
Sbjct: 225 CSKNCTNSPAIVRFSGQSRGVPAV---SESYSAPGACEEPTERGNLEVGEPQSEPVRVLD 281

Query: 247 ----------RKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGP 296
                     +++ +  PG      +FR + GR   A  +    G   +     P +   
Sbjct: 282 MVAKLESECLKRQGQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDT--- 338

Query: 297 GARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPP---- 352
                      +  + S S D  PS  +    + D+A +G S      +D PP P     
Sbjct: 339 ----------QVNPVGSVSVDCGPSRADRCSPKEDQAWDGAS------QDCPPLPAGVSF 382

Query: 353 -------PPPARDCGASGFHVDVVVTGVVDECIFFGKDGTK------------------- 386
                   P ++    +    DV +T  +    F     ++                   
Sbjct: 383 HIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHTYSQASELPTDAVDCMSRELVSL 442

Query: 387 -----NVKEETVCLTVSPE-------------EPPPPGQLFFL---------QNRGPDGP 419
                + ++E++C++++               E P PG LFFL                 
Sbjct: 443 TSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTT 502

Query: 420 PEPPPADSPATAPGPDDAE--------------GTADTSLCRLY-----RHVSHDFLEIR 460
            E   A     A G D A                + +++L  L      + VSHDFLE R
Sbjct: 503 KESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVESTLPVLEASSWKKQVSHDFLETR 562

Query: 461 FKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWS 520
           FKIQ+LLEP+QYM  LP H++VKIF  LPT++L ALKCTC +FK IIE + +R  DSRW 
Sbjct: 563 FKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYYNIRPADSRWV 622

Query: 521 RDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGL 580
           RDP YR+DPCKQC+K+Y KGDVSLCRWHPKPY   LPYG  YWMCC R+ +  PGC+LGL
Sbjct: 623 RDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGFPGCKLGL 682

Query: 581 HDNNWVLPCN 590
           HDN+WV  C+
Sbjct: 683 HDNHWVPACH 692


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 116/432 (26%), Positives = 139/432 (32%), Gaps = 64/432 (14%)

Query: 25   PRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRV 84
            P P   A  P A  +PG   EP    A  +  PP  A   PA  P P+ +  A G +G  
Sbjct: 808  PGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAG--PAGPPGPIGNVGAPGAKGA- 864

Query: 85   LLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKR-------RRRC 137
                     PG T    A       G    A      G  G +  K  R       R   
Sbjct: 865  ---RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGE 921

Query: 138  LDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAE---MVALVEQRAALALQSYPRPT 194
            + P   PP P G +G P A+ GPA A        +A    +V L  QR        P P+
Sbjct: 922  VGPP-GPPGPAGEKGSPGAD-GPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS 979

Query: 195  TPAPVVFVSAEQG--GPAKGVGSERRSGG-GDCSRVAEAVAHFEAQRD-SPPTKGLRKEE 250
                    S   G  GP   +G    +G  G+  R     A     RD SP  KG R E 
Sbjct: 980  GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039

Query: 251  RPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQ 310
             P   PG             P AP +  P G  G+ G    G  GP   A          
Sbjct: 1040 GPAGPPGA------------PGAPGAPGPVGPAGKSGDR--GETGPAGPAGP-------- 1077

Query: 311  LISPSRDALPSNVEFLLARADEASE-GDSPAPARPEDT----PPAPPPPPARDCGASGFH 365
             + P     P+  +       E  E GD         +    PP PP  P    G SG  
Sbjct: 1078 -VGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQ-GPSGAS 1135

Query: 366  VDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPA 425
                  G        GKDG   +          P    PPG      + GP GPP PP  
Sbjct: 1136 GPAGPRGPPGSAGAPGKDGLNGL----------PGPIGPPGPRGRTGDAGPVGPPGPP-- 1183

Query: 426  DSPATAPGPDDA 437
              P   PGP  A
Sbjct: 1184 -GPPGPPGPPSA 1194



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 86/319 (26%), Positives = 101/319 (31%), Gaps = 57/319 (17%)

Query: 144  PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPA----PV 199
            PP P G  GPP A+  P + GE  D               A      P P  PA    P+
Sbjct: 807  PPGPAGFAGPPGADGQPGAKGEPGD-------------AGAKGDAGPPGPAGPAGPPGPI 853

Query: 200  VFVSAEQGGPAKGVGSERRSGG--GDCSRVAEAVAHFEAQRDSPP-------TKGLRKEE 250
              V A     A+G      + G  G   RV        A    PP        KG R E 
Sbjct: 854  GNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGET 913

Query: 251  RPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPG----CAYPGSPGPGARAKDKITC 306
             P   PGEV           P  P    P+G  G PG       PG+PGP   A  +   
Sbjct: 914  GPAGRPGEV----------GPPGPPG--PAGEKGSPGADGPAGAPGTPGPQGIAGQRGVV 961

Query: 307  DL-YQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFH 365
             L  Q        LP          +   +G  P+ A  E  PP P  PP    G  G  
Sbjct: 962  GLPGQRGERGFPGLPG------PSGEPGKQG--PSGASGERGPPGPMGPPGL-AGPPGES 1012

Query: 366  VDVVVTGVVDECIFFGKDGTKNVKEET-----VCLTVSPEEPPPPGQLFFLQNRGPDGPP 420
                  G        G  G K  + ET          +P  P P G      +RG  GP 
Sbjct: 1013 GREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPA 1072

Query: 421  EPPPADSPATAPGPDDAEG 439
             P     P  A GP   +G
Sbjct: 1073 GPAGPVGPVGARGPAGPQG 1091



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 106/422 (25%), Positives = 127/422 (30%), Gaps = 54/422 (12%)

Query: 25  PRPPSAALKPSACPEPGGGAEPDH-GPAHSENTPPALATEVPASQPAPLLSAAAAGDEGR 83
           P P  AA +P    E G    P   GPA  +    A     PA           AG  G 
Sbjct: 583 PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF 642

Query: 84  VLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKA 143
             L       PG          A   G   +     V G  G+      R  R     + 
Sbjct: 643 QGL-------PGP---------AGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERG 686

Query: 144 PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVS 203
              P G  GP  A   P + G   D    A        + A  LQ  P     A +    
Sbjct: 687 VQGPPGPAGPRGANGAPGNDGAKGD----AGAPGAPGSQGAPGLQGMPGERGAAGLPGPK 742

Query: 204 AEQG--GPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRI 261
            ++G  GP    GS     G D  R             +P  KG   E  P    G    
Sbjct: 743 GDRGDAGPKGADGSP----GKDGVRGLTGPIGPPGPAGAPGDKG---ESGPSGPAGPTGA 795

Query: 262 AFRISNGREPRAPDSGLPSGGGGRPGC-AYPGSPGPGARAKDKITCDLYQLISPSRDALP 320
                +  EP  P    P+G  G PG    PG+ G    A  K          P+    P
Sbjct: 796 RGAPGDRGEPGPPG---PAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGP 852

Query: 321 -SNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIF 379
             NV    A+    S G   A   P       PP P+ + G  G                
Sbjct: 853 IGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPA----------- 901

Query: 380 FGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAEG 439
            GK+G K  + ET      P E  PPG        GP G    P AD PA APG    +G
Sbjct: 902 -GKEGGKGPRGETGPAG-RPGEVGPPGP------PGPAGEKGSPGADGPAGAPGTPGPQG 953

Query: 440 TA 441
            A
Sbjct: 954 IA 955



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 78/310 (25%), Positives = 96/310 (30%), Gaps = 77/310 (24%)

Query: 144 PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVS 203
           PP P G  GPP       + GE       A             ++  P P  PA      
Sbjct: 333 PPGPTGPAGPPGFPGAVGAKGE-------AGPQGPRGSEGPQGVRGEPGPPGPAGA---- 381

Query: 204 AEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAF 263
               GPA   G++ + G    ++ A            P  +G    + PG  PG      
Sbjct: 382 ---AGPAGNPGADGQPG----AKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPK---- 430

Query: 264 RISNGREPRAPDSGLPSGGGGRPG-CAYPGSPGP-------GARAKDKIT---CDLYQLI 312
              N  EP AP S   +G  G PG     G PGP       GAR +   T       +  
Sbjct: 431 --GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG 488

Query: 313 SPSRDALPSNVEFLLARADEASEGDSPAPARPEDTP-PAPPPPPARDCGASGFHVDVVVT 371
            P     P   + +      A E  SP PA P+ +P  A  P  A   GA G        
Sbjct: 489 GPGSRGFP-GADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKG-------- 539

Query: 372 GVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATA 431
                                  LT SP  P P G+          GPP P   D     
Sbjct: 540 -----------------------LTGSPGSPGPDGK---------TGPPGPAGQDGRPGP 567

Query: 432 PGPDDAEGTA 441
           PGP  A G A
Sbjct: 568 PGPPGARGQA 577



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 106/434 (24%), Positives = 140/434 (32%), Gaps = 95/434 (21%)

Query: 16  PFGTYSQNQPRPPSAALKPSACP----EPGG-GAEPDHGPAHSENTPPALATEVPASQPA 70
           P G   +  P  P+ A  P+  P    +PG  GA    G A +   P A     P     
Sbjct: 366 PQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGG 425

Query: 71  PLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSK 130
           P      +G+ G           PG+  +          G       + V+G  G    +
Sbjct: 426 PPGPKGNSGEPGA----------PGSKGDT---------GAKGEPGPVGVQGPPGPAGEE 466

Query: 131 AKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSY 190
            KR  R        P P G  GPP    GP S G        A+ VA             
Sbjct: 467 GKRGAR------GEPGPTGLPGPPGERGGPGSRG-----FPGADGVA------------- 502

Query: 191 PRPTTPAPVVFVSAEQG--GPAKGVGSERRSGGGDCSRVAEA-VAHFEAQRDSPPTKGLR 247
             P  PA       E+G  GPA   GS      G+  R  EA +   +    SP + G  
Sbjct: 503 -GPKGPA------GERGSPGPAGPKGSP-----GEAGRPGEAGLPGAKGLTGSPGSPGPD 550

Query: 248 KEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCD 307
            +  P PGP           G++ R    G P G  G+ G    G PGP   A +     
Sbjct: 551 GKTGP-PGPA----------GQDGRPGPPG-PPGARGQAGVM--GFPGPKGAAGEPGKAG 596

Query: 308 LYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVD 367
              +  P     P+             +G++ A   P    PA         G+ GF   
Sbjct: 597 ERGVPGPPGAVGPA-----------GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGL 645

Query: 368 VVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADS 427
               G   E    GK G + V  +      +P      G+  F   RG  GPP P     
Sbjct: 646 PGPAGPPGEA---GKPGEQGVPGD----LGAPGPSGARGERGFPGERGVQGPPGPAGPRG 698

Query: 428 PATAPGPDDAEGTA 441
              APG D A+G A
Sbjct: 699 ANGAPGNDGAKGDA 712



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 53/204 (25%), Positives = 61/204 (29%), Gaps = 43/204 (21%)

Query: 239 DSPPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGA 298
           D    K  R  ER  PGP           G       +GLP   G R      G+ G   
Sbjct: 232 DGEAGKPGRPGERGPPGP----------QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAG 281

Query: 299 RAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEG-DSPAPARPED--TPPAPPPPP 355
            A  K      +  SP  +  P  +       +    G   PA AR  D  T  A PP P
Sbjct: 282 PAGPK-----GEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGP 336

Query: 356 ARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRG 415
               G  GF   V   G        G +G + V                         RG
Sbjct: 337 TGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGV-------------------------RG 371

Query: 416 PDGPPEPPPADSPATAPGPDDAEG 439
             GPP P  A  PA  PG D   G
Sbjct: 372 EPGPPGPAGAAGPAGNPGADGQPG 395


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 75/288 (26%), Positives = 99/288 (34%), Gaps = 57/288 (19%)

Query: 185 LALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTK 244
           L  +++  P  PAP  F +      +  +      G G    +A   A    +R + P  
Sbjct: 608 LVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWV 667

Query: 245 GLRKEERPGPGPGEVRIAFRISNGREPRAP-----------DSGLP-------SGGGGRP 286
              +EE  G  PGE   +  +  G   R P            S LP       +G GG P
Sbjct: 668 EEEEEEEEGSSPGEDSSS--LGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHP 725

Query: 287 --GCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARP 344
             GC +P       RA+     DL   ++P   A P  ++ L+  A     G  P PA P
Sbjct: 726 ALGCPHPPEDDSSLRAERGSLADLP--MAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPP 783

Query: 345 EDTPPAPPPPPARDCGASGFHVDVVVT---------------GVVDECIFFGKD---GTK 386
              PP PPP    D  AS      V +               G   E  F  +    G  
Sbjct: 784 ---PPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGG 840

Query: 387 NVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGP 434
             +EE V    +P EPP PG             P PPP   P   PGP
Sbjct: 841 AAEEEGVPRPRAPPEPPDPGA------------PRPPPDPGPLPLPGP 876


>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
          Length = 663

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 107/443 (24%), Positives = 148/443 (33%), Gaps = 105/443 (23%)

Query: 14  PRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSEN------TPPALATEVPAS 67
           P   G  + +Q R   A L+        G A    GP H         +PP+ A   PA 
Sbjct: 57  PALAGPPAHSQLRAAVAHLRLRDLGADPGVATTPLGPEHMAQASTLGLSPPSQA--FPAH 114

Query: 68  QPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSD 127
             AP  +A AA            V  PG          ++ CGGGS           G+ 
Sbjct: 115 PEAPAAAARAAA----------LVAHPGAG--------SYPCGGGSS----------GAQ 146

Query: 128 SSKAKRRRRCLDPTKAPPDPGGREGPPAA-------EEGPASAGED--------VDLLSV 172
            S        L PT +PP P     PPA          G  S+G+          DL + 
Sbjct: 147 PSAPPPPAPPLPPTPSPPPPPPPPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSAT 206

Query: 173 AEMVAL------VEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSR 226
           A   A+       EQR+      +P P   +  +F+S      A G  +     GG    
Sbjct: 207 APAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFIS------ASGTYAGPDGSGGP--- 257

Query: 227 VAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRP 286
                A F A  D+P   G      P P  G++R+    +                  R 
Sbjct: 258 -----ALFPALHDTPGAPG----GHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRS 308

Query: 287 GCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPED 346
           G A+ G+    A A        Y  +         N+   LA A  A+        +   
Sbjct: 309 GDAHYGAVAAAAAA----ALHGYGAV---------NLNLNLAAAAAAAAAGPGPHLQHHA 355

Query: 347 TPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEE----P 402
            PPAPPPPPA        H    + G     + + +   + +K+E +C  + P+E    P
Sbjct: 356 PPPAPPPPPAPAQHPHQHHPH--LPGAAGAFLRYMR---QPIKQELICKWIDPDELAGLP 410

Query: 403 PPPGQLFFLQNRGPDGPPEPPPA 425
           PPP          P  PP PPPA
Sbjct: 411 PPPPP--------PPPPPPPPPA 425



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 30/111 (27%), Positives = 37/111 (33%), Gaps = 13/111 (11%)

Query: 339 PAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVS 398
           PAP  P    P PPPPP      SG+       G        GK  +++          +
Sbjct: 153 PAPPLPPTPSPPPPPPPPPPPALSGYTTTNSGGGGSS-----GKGHSRDFVLRRDLSATA 207

Query: 399 PEEPPPPGQLFFLQNRGPDGP--PEPPP------ADSPATAPGPDDAEGTA 441
           P        L   Q  G   P  P PPP        +  T  GPD + G A
Sbjct: 208 PAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGSGGPA 258


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 90/367 (24%), Positives = 123/367 (33%), Gaps = 57/367 (15%)

Query: 112  GSRASSMK--VKGHWGSDSSKAKRRRRCLDPTKAP---PDPGGREGPPAAEEGPASAGED 166
            G R ++ K   KG  G D        R L   + P   P P G  GPP  +  P   G+ 
Sbjct: 764  GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 823

Query: 167  VDL-----------LSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGS 215
             ++             V        +   +  + +P P  P        EQG P    G 
Sbjct: 824  GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP------GEQGLPGTA-GK 876

Query: 216  ERRSG-----GGDCSRVAEAVAHFEAQRDSPPTKG---LRKEERPGPGPGEVRIAFRISN 267
            E   G     G         +  F  +R  P T G   L+  E P   PG         +
Sbjct: 877  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA------GS 930

Query: 268  GREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDA------LPS 321
              E  A  SG P G  GRPG   P  P PGA  +  +  +   +    RD       LP 
Sbjct: 931  PGERGAAGSGGPIGPPGRPG---PQGP-PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 986

Query: 322  NVEFLLARADEASEGDSPAPARP-------EDTPPAPPPP--PARDCGASGFHVDVVVTG 372
                     ++  +G+   P +        E  PP PP P  P    GA+G   +    G
Sbjct: 987  PAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG 1046

Query: 373  VVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAP 432
                    G +GT+        + +    P P G+     + GP GPP PP    PA   
Sbjct: 1047 PQGHFGAKGDEGTRGFNGPPGPIGLQGL-PGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1105

Query: 433  GPDDAEG 439
            G D  +G
Sbjct: 1106 GADGPQG 1112



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 84/318 (26%), Positives = 107/318 (33%), Gaps = 57/318 (17%)

Query: 142  KAPPDPGGREGP--PAAEEGPAS----AGEDVDLLSVAEMVALVEQRAALALQSYPRPTT 195
            K P  P GR+G   P    GPA     AGED D   V +      Q+     +    P  
Sbjct: 967  KGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP----GQKGTKGNKGEHGPPG 1022

Query: 196  PAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPG 255
            P           GP   VG    +G            HF A+ D    +G R    P PG
Sbjct: 1023 PP----------GPIGPVGQPGAAGADGEPGARGPQGHFGAKGD----EGTRGFNGP-PG 1067

Query: 256  PGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPS 315
            P  ++      +G +    D G P G  G PG   P  P  GA         +  L  P 
Sbjct: 1068 PIGLQ-GLPGPSGEKGETGDVG-PMGPPGPPGPRGPAGPN-GADGPQGPPGGVGNLGPPG 1124

Query: 316  RDALPSNVE---------FLLARADEASEGDSPAPARPEDTPPAPPPP-----PARDCGA 361
                P                 R +   +G+S  P  P   PP P  P     P  + G 
Sbjct: 1125 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG--PPGPKGPTGDDGPKGNPGP 1182

Query: 362  SGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPE 421
             GF  D    G   E    G+DG K  + E       P +P  PG        G +GPP 
Sbjct: 1183 VGFPGD---PGPPGEGGPRGQDGAKGDRGEDG----EPGQPGSPGPT------GENGPPG 1229

Query: 422  PPPADSPATAPGPDDAEG 439
            P     PA +PG +  +G
Sbjct: 1230 PLGKRGPAGSPGSEGRQG 1247



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 91/398 (22%), Positives = 119/398 (29%), Gaps = 116/398 (29%)

Query: 108 QCGGGSRASSMKVKGHWGSDSSKAK----RRRRCLDPTKAPPDPGGREG-------PPAA 156
           +C GG R      + H    S + +     R +  +P    P PG  E        PP  
Sbjct: 227 ECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLE 286

Query: 157 E--EGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVG 214
           E   GP     +    +V E   LVE          P P  PA ++     QG P   VG
Sbjct: 287 EAAHGPRGLKGEKGEPAVLEPGMLVE--------GPPGPEGPAGLIGPPGIQGNPGP-VG 337

Query: 215 SERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEE-RPGPGPGEVRIAFRISNGREPRA 273
                                 +R  P   GL   +  PGP    + + FR  +G   + 
Sbjct: 338 DP-------------------GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG 378

Query: 274 PDSGL---------------------PSGGGGRPG-CAYPGSPGPGARAKDKITCDLYQL 311
           P                         P G  GRPG    PGSPG    + D         
Sbjct: 379 PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD--------- 429

Query: 312 ISPSRDALPSNVEFLLARADE----ASEGDSPAPARP--------EDTPPAP-------- 351
           + P     P  +     +A       ++G    P  P        +  P  P        
Sbjct: 430 LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGD 489

Query: 352 ------PPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPP 405
                 P PP  D G  G   ++   G+  E    G  G K            P  P PP
Sbjct: 490 TGAQGLPGPPGED-GERGDDGEIGPRGLPGESGPRGLLGPKG----------PPGIPGPP 538

Query: 406 GQLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGTADT 443
           G       RG DGP  P  +  P   PGP   +GT  T
Sbjct: 539 GV------RGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 570



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 75/322 (23%), Positives = 100/322 (31%), Gaps = 51/322 (15%)

Query: 144  PPDPGGREGP--PAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVF 201
            PP P G  GP  P   +GP      V  L          +  +  +Q  P    P     
Sbjct: 1092 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1151

Query: 202  VSAEQGGPAK-GVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVR 260
               E G P + G    +   G D  +       F      P   G R ++      GE  
Sbjct: 1152 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGE-- 1209

Query: 261  IAFRISNGREPRAPDSGLPSGGGGRPG-------CAYPGSPG----------PGARAKDK 303
                     EP  P S  P+G  G PG          PGS G          PGA     
Sbjct: 1210 -------DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1262

Query: 304  ITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPAR-----D 358
             T      + P+  A     + L        +   P  A  +  PP P  PP       D
Sbjct: 1263 KTGP----VGPAGPAGKPGPDGLRGLPGSVGQQGRPG-ATGQAGPPGPVGPPGLPGLRGD 1317

Query: 359  CGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPE-EPPPPGQLFFLQNRGPD 417
             GA G      + G++      G+ G + +          P+  P   G++      GP 
Sbjct: 1318 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP--------GPQGSPGQKGEMGIPGASGPI 1369

Query: 418  GPPEPPPADSPATAPGPDDAEG 439
            GP  PP    PA   GP  A+G
Sbjct: 1370 GPGGPPGLPGPA---GPKGAKG 1388



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 108/474 (22%), Positives = 143/474 (30%), Gaps = 99/474 (20%)

Query: 14  PRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLL 73
           P P G    +  + P    KP     PG    P H     E  P     + P+    PL 
Sbjct: 574 PGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGH--PGKEGPPGTKGNQGPSGPQGPLG 629

Query: 74  SAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRAS--SMKVKGHWGSDSSKA 131
                G +G   +D    +K    ++    F   +   G +     + V G  G D  + 
Sbjct: 630 YPGPRGVKG---VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 686

Query: 132 KRRRRCLDPTKAPPDPG-----GREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRA-AL 185
            + R    PT  P  PG     G+ G P     P   G    L       A  E+ A  L
Sbjct: 687 PKGRT--GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 744

Query: 186 ALQSYPR----PTTPAPVVFVSAEQGGP--AKGVGSERRSGGGDCSRVA---------EA 230
           + +S PR    PT P         Q GP  A G    + + GGD              + 
Sbjct: 745 SGKSGPRGERGPTGPRG-------QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG 797

Query: 231 VAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGC-- 288
              F   +  P   G  K+  PG       + F+   G  P  P    P G  G  G   
Sbjct: 798 PNGFPGPKGPPGPPG--KDGLPGHPGQRGEVGFQGKTG-PPGPPGVVGPQGAAGETGPMG 854

Query: 289 --AYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPED 346
              +PG PGP                 P    LP           E ++GD         
Sbjct: 855 ERGHPGPPGP-----------------PGEQGLPGTA------GKEGTKGD--------- 882

Query: 347 TPPAPPPPPARD--CGASGFHVDVVVTGVVDECIFFGKDGTKNVK-------EETVCLTV 397
             P PP  P +D   G  GF  +  + G        G +G            E     + 
Sbjct: 883 --PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG 940

Query: 398 SPEEPP-------PPG---QLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGTA 441
            P  PP       PPG   +      +GP GP        P   PGP    G A
Sbjct: 941 GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 994


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 90/367 (24%), Positives = 123/367 (33%), Gaps = 57/367 (15%)

Query: 112  GSRASSMK--VKGHWGSDSSKAKRRRRCLDPTKAP---PDPGGREGPPAAEEGPASAGED 166
            G R ++ K   KG  G D        R L   + P   P P G  GPP  +  P   G+ 
Sbjct: 743  GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 802

Query: 167  VDL-----------LSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGS 215
             ++             V        +   +  + +P P  P        EQG P    G 
Sbjct: 803  GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP------GEQGLPGTA-GK 855

Query: 216  ERRSG-----GGDCSRVAEAVAHFEAQRDSPPTKG---LRKEERPGPGPGEVRIAFRISN 267
            E   G     G         +  F  +R  P T G   L+  E P   PG         +
Sbjct: 856  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA------GS 909

Query: 268  GREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDA------LPS 321
              E  A  SG P G  GRPG   P  P PGA  +  +  +   +    RD       LP 
Sbjct: 910  PGERGAAGSGGPIGPPGRPG---PQGP-PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 965

Query: 322  NVEFLLARADEASEGDSPAPARP-------EDTPPAPPPP--PARDCGASGFHVDVVVTG 372
                     ++  +G+   P +        E  PP PP P  P    GA+G   +    G
Sbjct: 966  PAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG 1025

Query: 373  VVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAP 432
                    G +GT+        + +    P P G+     + GP GPP PP    PA   
Sbjct: 1026 PQGHFGAKGDEGTRGFNGPPGPIGLQGL-PGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1084

Query: 433  GPDDAEG 439
            G D  +G
Sbjct: 1085 GADGPQG 1091



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 84/318 (26%), Positives = 107/318 (33%), Gaps = 57/318 (17%)

Query: 142  KAPPDPGGREGP--PAAEEGPAS----AGEDVDLLSVAEMVALVEQRAALALQSYPRPTT 195
            K P  P GR+G   P    GPA     AGED D   V +      Q+     +    P  
Sbjct: 946  KGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP----GQKGTKGNKGEHGPPG 1001

Query: 196  PAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPG 255
            P           GP   VG    +G            HF A+ D    +G R    P PG
Sbjct: 1002 PP----------GPIGPVGQPGAAGADGEPGARGPQGHFGAKGD----EGTRGFNGP-PG 1046

Query: 256  PGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPS 315
            P  ++      +G +    D G P G  G PG   P  P  GA         +  L  P 
Sbjct: 1047 PIGLQ-GLPGPSGEKGETGDVG-PMGPPGPPGPRGPAGPN-GADGPQGPPGGVGNLGPPG 1103

Query: 316  RDALPSNVE---------FLLARADEASEGDSPAPARPEDTPPAPPPP-----PARDCGA 361
                P                 R +   +G+S  P  P   PP P  P     P  + G 
Sbjct: 1104 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG--PPGPKGPTGDDGPKGNPGP 1161

Query: 362  SGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPE 421
             GF  D    G   E    G+DG K  + E       P +P  PG        G +GPP 
Sbjct: 1162 VGFPGD---PGPPGEGGPRGQDGAKGDRGEDG----EPGQPGSPGPT------GENGPPG 1208

Query: 422  PPPADSPATAPGPDDAEG 439
            P     PA +PG +  +G
Sbjct: 1209 PLGKRGPAGSPGSEGRQG 1226



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 75/322 (23%), Positives = 100/322 (31%), Gaps = 51/322 (15%)

Query: 144  PPDPGGREGP--PAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVF 201
            PP P G  GP  P   +GP      V  L          +  +  +Q  P    P     
Sbjct: 1071 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1130

Query: 202  VSAEQGGPAK-GVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVR 260
               E G P + G    +   G D  +       F      P   G R ++      GE  
Sbjct: 1131 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGE-- 1188

Query: 261  IAFRISNGREPRAPDSGLPSGGGGRPG-------CAYPGSPG----------PGARAKDK 303
                     EP  P S  P+G  G PG          PGS G          PGA     
Sbjct: 1189 -------DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1241

Query: 304  ITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPAR-----D 358
             T      + P+  A     + L        +   P  A  +  PP P  PP       D
Sbjct: 1242 KTGP----VGPAGPAGKPGPDGLRGLPGSVGQQGRPG-ATGQAGPPGPVGPPGLPGLRGD 1296

Query: 359  CGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPE-EPPPPGQLFFLQNRGPD 417
             GA G      + G++      G+ G + +          P+  P   G++      GP 
Sbjct: 1297 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP--------GPQGSPGQKGEMGIPGASGPI 1348

Query: 418  GPPEPPPADSPATAPGPDDAEG 439
            GP  PP    PA   GP  A+G
Sbjct: 1349 GPGGPPGLPGPA---GPKGAKG 1367



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 108/474 (22%), Positives = 143/474 (30%), Gaps = 99/474 (20%)

Query: 14  PRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLL 73
           P P G    +  + P    KP     PG    P H     E  P     + P+    PL 
Sbjct: 553 PGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGH--PGKEGPPGTKGNQGPSGPQGPLG 608

Query: 74  SAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRAS--SMKVKGHWGSDSSKA 131
                G +G   +D    +K    ++    F   +   G +     + V G  G D  + 
Sbjct: 609 YPGPRGVKG---VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 665

Query: 132 KRRRRCLDPTKAPPDPG-----GREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRA-AL 185
            + R    PT  P  PG     G+ G P     P   G    L       A  E+ A  L
Sbjct: 666 PKGRT--GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723

Query: 186 ALQSYPR----PTTPAPVVFVSAEQGGP--AKGVGSERRSGGGDCSRVA---------EA 230
           + +S PR    PT P         Q GP  A G    + + GGD              + 
Sbjct: 724 SGKSGPRGERGPTGPRG-------QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG 776

Query: 231 VAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGC-- 288
              F   +  P   G  K+  PG       + F+   G  P  P    P G  G  G   
Sbjct: 777 PNGFPGPKGPPGPPG--KDGLPGHPGQRGEVGFQGKTG-PPGPPGVVGPQGAAGETGPMG 833

Query: 289 --AYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPED 346
              +PG PGP                 P    LP           E ++GD         
Sbjct: 834 ERGHPGPPGP-----------------PGEQGLPGTA------GKEGTKGD--------- 861

Query: 347 TPPAPPPPPARD--CGASGFHVDVVVTGVVDECIFFGKDGTKNVK-------EETVCLTV 397
             P PP  P +D   G  GF  +  + G        G +G            E     + 
Sbjct: 862 --PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG 919

Query: 398 SPEEPP-------PPG---QLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGTA 441
            P  PP       PPG   +      +GP GP        P   PGP    G A
Sbjct: 920 GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 973



 Score = 33.1 bits (74), Expect = 0.75
 Identities = 86/385 (22%), Positives = 113/385 (29%), Gaps = 111/385 (28%)

Query: 108 QCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDV 167
           +C GG R      + H    S + +  R           P  +E    A  GP     + 
Sbjct: 227 ECEGGQRERPQNQQPHRAQRSPQQQPSRL--------HRPQNQEPQSQAAHGPRGLKGEK 278

Query: 168 DLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRV 227
              +V E   LVE          P P  PA ++     QG P   VG             
Sbjct: 279 GEPAVLEPGMLVE--------GPPGPEGPAGLIGPPGIQGNPGP-VGDP----------- 318

Query: 228 AEAVAHFEAQRDSPPTKGLRKEE-RPGPGPGEVRIAFRISNGREPRAPDSGL-------- 278
                    +R  P   GL   +  PGP    + + FR  +G   + P            
Sbjct: 319 --------GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAI 370

Query: 279 -------------PSGGGGRPG-CAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVE 324
                        P G  GRPG    PGSPG    + D         + P     P  + 
Sbjct: 371 LQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD---------LGPQGPRGPQGLT 421

Query: 325 FLLARADE----ASEGDSPAPARP--------EDTPPAP--------------PPPPARD 358
               +A       ++G    P  P        +  P  P              P PP  D
Sbjct: 422 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 481

Query: 359 CGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDG 418
            G  G   ++   G+  E    G  G K            P  P PPG       RG DG
Sbjct: 482 -GERGDDGEIGPRGLPGESGPRGLLGPKG----------PPGIPGPPGV------RGMDG 524

Query: 419 PPEPPPADSPATAPGPDDAEGTADT 443
           P  P  +  P   PGP   +GT  T
Sbjct: 525 PQGPKGSLGPQGEPGPPGQQGTPGT 549


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 90/367 (24%), Positives = 123/367 (33%), Gaps = 57/367 (15%)

Query: 112  GSRASSMK--VKGHWGSDSSKAKRRRRCLDPTKAP---PDPGGREGPPAAEEGPASAGED 166
            G R ++ K   KG  G D        R L   + P   P P G  GPP  +  P   G+ 
Sbjct: 850  GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 909

Query: 167  VDL-----------LSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGS 215
             ++             V        +   +  + +P P  P        EQG P    G 
Sbjct: 910  GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP------GEQGLPGTA-GK 962

Query: 216  ERRSG-----GGDCSRVAEAVAHFEAQRDSPPTKG---LRKEERPGPGPGEVRIAFRISN 267
            E   G     G         +  F  +R  P T G   L+  E P   PG         +
Sbjct: 963  EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA------GS 1016

Query: 268  GREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDA------LPS 321
              E  A  SG P G  GRPG   P  P PGA  +  +  +   +    RD       LP 
Sbjct: 1017 PGERGAAGSGGPIGPPGRPG---PQGP-PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 1072

Query: 322  NVEFLLARADEASEGDSPAPARP-------EDTPPAPPPP--PARDCGASGFHVDVVVTG 372
                     ++  +G+   P +        E  PP PP P  P    GA+G   +    G
Sbjct: 1073 PAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG 1132

Query: 373  VVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAP 432
                    G +GT+        + +    P P G+     + GP GPP PP    PA   
Sbjct: 1133 PQGHFGAKGDEGTRGFNGPPGPIGLQGL-PGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1191

Query: 433  GPDDAEG 439
            G D  +G
Sbjct: 1192 GADGPQG 1198



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 84/318 (26%), Positives = 107/318 (33%), Gaps = 57/318 (17%)

Query: 142  KAPPDPGGREGP--PAAEEGPAS----AGEDVDLLSVAEMVALVEQRAALALQSYPRPTT 195
            K P  P GR+G   P    GPA     AGED D   V +      Q+     +    P  
Sbjct: 1053 KGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP----GQKGTKGNKGEHGPPG 1108

Query: 196  PAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPG 255
            P           GP   VG    +G            HF A+ D    +G R    P PG
Sbjct: 1109 PP----------GPIGPVGQPGAAGADGEPGARGPQGHFGAKGD----EGTRGFNGP-PG 1153

Query: 256  PGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPS 315
            P  ++      +G +    D G P G  G PG   P  P  GA         +  L  P 
Sbjct: 1154 PIGLQ-GLPGPSGEKGETGDVG-PMGPPGPPGPRGPAGPN-GADGPQGPPGGVGNLGPPG 1210

Query: 316  RDALPSNVE---------FLLARADEASEGDSPAPARPEDTPPAPPPP-----PARDCGA 361
                P                 R +   +G+S  P  P   PP P  P     P  + G 
Sbjct: 1211 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG--PPGPKGPTGDDGPKGNPGP 1268

Query: 362  SGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPE 421
             GF  D    G   E    G+DG K  + E       P +P  PG        G +GPP 
Sbjct: 1269 VGFPGD---PGPPGEGGPRGQDGAKGDRGEDG----EPGQPGSPGPT------GENGPPG 1315

Query: 422  PPPADSPATAPGPDDAEG 439
            P     PA +PG +  +G
Sbjct: 1316 PLGKRGPAGSPGSEGRQG 1333



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 75/322 (23%), Positives = 100/322 (31%), Gaps = 51/322 (15%)

Query: 144  PPDPGGREGP--PAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVF 201
            PP P G  GP  P   +GP      V  L          +  +  +Q  P    P     
Sbjct: 1178 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1237

Query: 202  VSAEQGGPAK-GVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVR 260
               E G P + G    +   G D  +       F      P   G R ++      GE  
Sbjct: 1238 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGE-- 1295

Query: 261  IAFRISNGREPRAPDSGLPSGGGGRPG-------CAYPGSPG----------PGARAKDK 303
                     EP  P S  P+G  G PG          PGS G          PGA     
Sbjct: 1296 -------DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1348

Query: 304  ITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPAR-----D 358
             T      + P+  A     + L        +   P  A  +  PP P  PP       D
Sbjct: 1349 KTGP----VGPAGPAGKPGPDGLRGLPGSVGQQGRPG-ATGQAGPPGPVGPPGLPGLRGD 1403

Query: 359  CGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPE-EPPPPGQLFFLQNRGPD 417
             GA G      + G++      G+ G + +          P+  P   G++      GP 
Sbjct: 1404 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLP--------GPQGSPGQKGEMGIPGASGPI 1455

Query: 418  GPPEPPPADSPATAPGPDDAEG 439
            GP  PP    PA   GP  A+G
Sbjct: 1456 GPGGPPGLPGPA---GPKGAKG 1474



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 108/474 (22%), Positives = 143/474 (30%), Gaps = 99/474 (20%)

Query: 14   PRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLL 73
            P P G    +  + P    KP     PG    P H     E  P     + P+    PL 
Sbjct: 660  PGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGH--PGKEGPPGTKGNQGPSGPQGPLG 715

Query: 74   SAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRAS--SMKVKGHWGSDSSKA 131
                 G +G   +D    +K    ++    F   +   G +     + V G  G D  + 
Sbjct: 716  YPGPRGVKG---VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 772

Query: 132  KRRRRCLDPTKAPPDPG-----GREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRA-AL 185
             + R    PT  P  PG     G+ G P     P   G    L       A  E+ A  L
Sbjct: 773  PKGRT--GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 830

Query: 186  ALQSYPR----PTTPAPVVFVSAEQGGP--AKGVGSERRSGGGDCSRVA---------EA 230
            + +S PR    PT P         Q GP  A G    + + GGD              + 
Sbjct: 831  SGKSGPRGERGPTGPRG-------QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQG 883

Query: 231  VAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGC-- 288
               F   +  P   G  K+  PG       + F+   G  P  P    P G  G  G   
Sbjct: 884  PNGFPGPKGPPGPPG--KDGLPGHPGQRGEVGFQGKTG-PPGPPGVVGPQGAAGETGPMG 940

Query: 289  --AYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPED 346
               +PG PGP                 P    LP           E ++GD         
Sbjct: 941  ERGHPGPPGP-----------------PGEQGLPGTA------GKEGTKGD--------- 968

Query: 347  TPPAPPPPPARD--CGASGFHVDVVVTGVVDECIFFGKDGTKNVK-------EETVCLTV 397
              P PP  P +D   G  GF  +  + G        G +G            E     + 
Sbjct: 969  --PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG 1026

Query: 398  SPEEPP-------PPG---QLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGTA 441
             P  PP       PPG   +      +GP GP        P   PGP    G A
Sbjct: 1027 GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA 1080



 Score = 32.7 bits (73), Expect = 0.99
 Identities = 68/246 (27%), Positives = 86/246 (34%), Gaps = 68/246 (27%)

Query: 219 SGGGD-----CSRVAEAVAHFEAQRDS--PPTKGLRKEERPGP--GPGEVRIAFRISN-- 267
           SGGGD      ++ A+A A  +  R +   P   +    RPGP   PG   +     +  
Sbjct: 458 SGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG 517

Query: 268 GREPRAPDSGL--PSGGGGRPGCA-------YPGSPG-PGARAKDKITCDLYQLISPSRD 317
            + PR P  GL  P G  GR G A        PG PG  G R  D +             
Sbjct: 518 PQGPRGPQ-GLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP------------ 564

Query: 318 ALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDEC 377
            LP          ++   GD+ A   P         PP  D G  G   ++   G+  E 
Sbjct: 565 GLPG---------EKGHRGDTGAQGLPG--------PPGED-GERGDDGEIGPRGLPGES 606

Query: 378 IFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDA 437
              G  G K            P  P PPG       RG DGP  P  +  P   PGP   
Sbjct: 607 GPRGLLGPKG----------PPGIPGPPGV------RGMDGPQGPKGSLGPQGEPGPPGQ 650

Query: 438 EGTADT 443
           +GT  T
Sbjct: 651 QGTPGT 656


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 78/320 (24%), Positives = 110/320 (34%), Gaps = 54/320 (16%)

Query: 139 DPTKAPPDPGGREGP---PAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTT 195
           D T  P +    E P    + EE P+S  +DV                  A    P P  
Sbjct: 254 DLTCTPEEEENEEKPLLEVSPEERPSSGQQDV------------------APDRGPEPGP 295

Query: 196 PAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPG 255
           PAP+         P  G    RR+     S +  +V       + P ++    E      
Sbjct: 296 PAPL---------PPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPES 346

Query: 256 PGEVRIAFRISNGREPRAPDSGLPS---GGGGRPGCAYPGSP-GPGARAKDKITCDLYQL 311
              +R+        EP +P  G P+    GG + G A P  P  P     +++ C    +
Sbjct: 347 APTLRV--------EPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDV 398

Query: 312 ISPSRDALPSN----VEFLLARADEA-SEGDSPAPARPEDTPPAPPPPPARDCGASGFHV 366
            SP   A+P       E   A   EA S  D P  + P++  P PP  P  + G  G   
Sbjct: 399 ASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAP 458

Query: 367 DVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPP-- 424
           +       +     G +  +   E +     SP  P P   L        +GP   PP  
Sbjct: 459 EPEREAETEPERGAGTEPERIGTEPSTAPAPSP--PAPKSCLKHRPAAASEGPAASPPLA 516

Query: 425 -ADSPATAPGPD--DAEGTA 441
            A+SP   PGP   DAE  A
Sbjct: 517 AAESPPVEPGPGSLDAEAAA 536


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 77/362 (21%), Positives = 119/362 (32%), Gaps = 44/362 (12%)

Query: 24   QPRPPSAALKPSA---CPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAA-- 78
            +P PP  +  P A   CP P   AE    PA + +  PA    +PA++P P  + AA   
Sbjct: 2390 RPAPPQPSPAPPAFTSCPAPEPFAEL---PAPATSLAPAPLITMPATRPKPKKARAAEES 2446

Query: 79   --------GDEGRVL--LDTWYVIKPGNTKEKVAFFVAHQ--CGGGSRASSMKVKGHW-- 124
                    G+E  +L  LD   V  P + K K A  +      GG     S+   G +  
Sbjct: 2447 GAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPP 2506

Query: 125  --GSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQR 182
              GS   KA             P P   +G  A E GP    ED       +     +  
Sbjct: 2507 AAGSSEPKA-------------PWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDG 2553

Query: 183  AALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPP 242
            A  +  S    +  +     S+  G   +G     ++G G C       +   ++  SP 
Sbjct: 2554 AEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPA 2613

Query: 243  TKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAK- 301
            +                  +   S+     +  S   S        +   S    + +  
Sbjct: 2614 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTT 2673

Query: 302  -DKITCDLYQLISPSRDALPSNVEFLLARADEAS-----EGDSPAPARPEDTPPAPPPPP 355
             +  +C      +P+  A PS    L  +A + +        SP    P   P APPP P
Sbjct: 2674 DEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQP 2733

Query: 356  AR 357
             +
Sbjct: 2734 TQ 2735


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 104/418 (24%), Positives = 136/418 (32%), Gaps = 85/418 (20%)

Query: 25  PRPPSAALKPSACPEPGGGAEPDHGPAHSEN-------TPPALATEVP------ASQPAP 71
           P PP     P+    PGGG     GP             PPA     P      +  P P
Sbjct: 87  PEPP-----PAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVP 141

Query: 72  LLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKA 131
             +A AAG E             G  K      +A + G G                   
Sbjct: 142 AAAAVAAGPEPA---------PAGPAKPAGPAALAARAGPGPGPG--------------- 177

Query: 132 KRRRRCLDPTKAP-PDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSY 190
                   P   P P PG   GP AA+    SA       + A  V+LV    A AL   
Sbjct: 178 --------PGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA-ALLPL 228

Query: 191 PRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEE 250
           P+P  P  V+     Q  P  G  +   +        A A A   A    PP        
Sbjct: 229 PKPAAPGTVI-----QTPPFVGAAAPP-APAAPSPPAAPAPAAPAAAPPPPPPAPATLAR 282

Query: 251 RPGPGPGEVRIAFRI----------SNGREPR-APDSGLPSGGGGRPG-CAYPGSPGPGA 298
            PG   G    A  +          S G  P  AP +G P+G  G+PG  A   +P PG 
Sbjct: 283 PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGV 342

Query: 299 RAKDKITCDLYQLISPSRDALPSNVEFLLARA---DEASEGDSPAPARPEDTPPAPPPPP 355
           +A+      + Q   P+   L ++     A +       +G  P+PA     PPAP  P 
Sbjct: 343 KAESPKR--VVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAV--PPPAPGTPT 398

Query: 356 ARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQN 413
               GA+G      VT  +         G +     TV   ++P  P PP     +QN
Sbjct: 399 GLPKGAAG-----AVTQSLSRTPTATTSGIRATLTPTV---LAPRLPQPPQNPTNIQN 448



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 70/298 (23%), Positives = 91/298 (30%), Gaps = 57/298 (19%)

Query: 166 DVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCS 225
           +VD   V+++V  +E + A +   +       P V  +A  G     V S   +G     
Sbjct: 16  EVDEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAA-GALGNHVVSGSPAGAAGAG 74

Query: 226 RVAEAVAHFEAQRDSPPTKGLRK----EERPGPGPGEVRIAFRISNGREPRAPDSGLPSG 281
             A A     A  + PP    R      +RPGP            + R P  P    P  
Sbjct: 75  PAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGP-----------PSPRRPLVPAGPAPPA 123

Query: 282 GGGRP---GCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDS 338
              RP   G A   +P P A A            +P+  A P+    L ARA     G  
Sbjct: 124 AKLRPPPEGSAGSCAPVPAAAA-----VAAGPEPAPAGPAKPAGPAALAARA---GPGPG 175

Query: 339 PAPARPEDTPPAPPPPPARDCGA-------------SGFHVDVVVTGVVDECIFFGKDGT 385
           P P       P P P P +  G              +  H       +V+          
Sbjct: 176 PGPG------PGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLP 229

Query: 386 KNVKEETVCLT---VSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGT 440
           K     TV  T   V    PP P          P  P  P PA   A  P P  A  T
Sbjct: 230 KPAAPGTVIQTPPFVGAAAPPAPA--------APSPPAAPAPAAPAAAPPPPPPAPAT 279


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 87/340 (25%), Positives = 109/340 (32%), Gaps = 76/340 (22%)

Query: 122  GHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQ 181
            GH+G+   +       L   + P    GR GPP +  GP     D  +  +      +  
Sbjct: 1097 GHFGASGEQG------LPGIQGPRGSPGRPGPPGSS-GPPGCPGDHGMPGLRGQPGEMGD 1149

Query: 182  RAALALQSYPRPTTPAPVVFVSAEQG-----GPAKGVGSERRSGGGDCSRVAEA-VAHFE 235
                 LQ  P    P  +   S   G     G     G++  SG  D        +   +
Sbjct: 1150 PGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLK 1209

Query: 236  AQRDSPPTKGLR------KEERPGPGPGEVRIAFRISNGREPR-APDSGLPSGGGGRPGC 288
             +R  P + G+       K+  PGP           + GR P+  PD G P G  G PG 
Sbjct: 1210 GERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPG-PPGDQGPPGP 1268

Query: 289  AYP-GSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDT 347
              P G+PGP                      LP +V+ L         GD   P  P   
Sbjct: 1269 DGPRGAPGP--------------------PGLPGSVDLL-----RGEPGDCGLPGPPG-- 1301

Query: 348  PPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQ 407
            PP PP PP    G  GF            C   GKDG K               P P G 
Sbjct: 1302 PPGPPGPP----GYKGF----------PGCD--GKDGQKG----------PVGFPGPQGP 1335

Query: 408  LFFLQNRGPDGPPEPPPADSPATAPGPDDAEG-TADTSLC 446
              F    G  G P PP    P   PGP    G  AD   C
Sbjct: 1336 HGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDC 1375



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 86/347 (24%), Positives = 110/347 (31%), Gaps = 87/347 (25%)

Query: 142  KAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYP----RPTTPA 197
            +  P   G+ GPP     P S G                 R  +     P     P +P 
Sbjct: 1014 RGEPGEKGQPGPPGPPGPPGSTG----------------LRGFIGFPGLPGDQGEPGSPG 1057

Query: 198  PVVFVSAEQGGPAKGVGSERRSGGGDCSRVAE-----AVAHFEAQRDS--PPTKGLRKEE 250
            P  F   +     KG   +  S  G      E        HF A  +   P  +G R   
Sbjct: 1058 PPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSP 1117

Query: 251  -RPGPGPGEVRIAFRISNGREPRAPDSGLPS-----GGGGRPGC----AYPGSPGP---- 296
             RPGP PG        S+G      D G+P      G  G PG       PG PGP    
Sbjct: 1118 GRPGP-PG--------SSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIK 1168

Query: 297  ------------GARAKD--KITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPA 342
                        G + +   K    L+ +  P    +P        R D  S G SP   
Sbjct: 1169 GPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPG---LKGERGDPGSPGISPPGP 1225

Query: 343  RPEDTPPAPPPP--PARDCGASG-FHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSP 399
            R +  PP PP    P    GA+G    D+   G   +    G DG +           +P
Sbjct: 1226 RGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRG----------AP 1275

Query: 400  EEPPPPGQLFFLQNR-------GPDGPPEPPPADSPATAPGPDDAEG 439
              P  PG +  L+         GP GPP PP        PG D  +G
Sbjct: 1276 GPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDG 1322



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 46/187 (24%), Positives = 58/187 (31%), Gaps = 50/187 (26%)

Query: 261 IAFRISNGREPRAPDSGLPSGGGGRPG-------CAYPGSPGPGARAKDKITCDLYQLIS 313
           +  R+   +  R PD   P G  G+PG           G PGP    +D          +
Sbjct: 560 VVSRVKGHKGERGPDG--PPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDA---------T 608

Query: 314 PSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGV 373
           P     P  +               P  A P   P    P P  + G  G      V G 
Sbjct: 609 PGGKGFPGPL-------------GPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRG- 654

Query: 374 VDECIFFGKDGTKNVKEETV-CLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAP 432
                    DG K  K +T+ C    P    PPG          DGPP P     P  AP
Sbjct: 655 --------PDGLKGQKGDTISCNVTYPGRHGPPGF---------DGPPGPKGFPGPQGAP 697

Query: 433 GPDDAEG 439
           G   ++G
Sbjct: 698 GLSGSDG 704



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 62/265 (23%), Positives = 89/265 (33%), Gaps = 44/265 (16%)

Query: 208 GPAKGVGSERRSGG-GDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRIS 266
           GP   +G     G  G+   +  AV   +  R  P   GL      G   G         
Sbjct: 158 GPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGY----- 212

Query: 267 NGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFL 326
               P  P    P G  GRPG    G+PG G + +     ++ Q  SP    L    +F 
Sbjct: 213 ----PGEPGLVGPPGQPGRPGLK--GNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFC 266

Query: 327 LARADEA---------------SEGDSPAPARPEDTPPAPPPPPAR--DCGASGFHVDVV 369
           L + ++                 +G+S   A+ E   P  P P       G+ GF     
Sbjct: 267 LYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKG 326

Query: 370 VTGVVDECIFFGKDGTKN-------------VKEETVCLTVSPEEPPPPGQLFFLQNRGP 416
             G+V +   FG  G K              +    + L   P +P  PG+     + GP
Sbjct: 327 ELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGP 386

Query: 417 DGPPE--PPPADSPATAPGPDDAEG 439
            GPP     P ++ A   GP   +G
Sbjct: 387 PGPPGLLGRPGEACAGMIGPPGPQG 411



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 78/307 (25%), Positives = 106/307 (34%), Gaps = 68/307 (22%)

Query: 145 PDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRP-----TTPAPV 199
           P P G  G   +   P   GE + L+    +  L+  +     + +P P     T P P+
Sbjct: 307 PGPRGDPGSYGSPGFPGLKGE-LGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPL 365

Query: 200 VFVSAEQGGPAK-GVGSERRSGG--GDCSRVAEAVAHFEAQRDSPPTKGLRKEERPG-PG 255
                + G P + G   +    G  G   R  EA A        P  +G      PG PG
Sbjct: 366 KGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACA---GMIGPPGPQGF-----PGLPG 417

Query: 256 -PGEVRIAFRISNGREPRAPDSGLPSGGGGRPGC-AYPGSPG-PGARAKDKITCDLYQLI 312
            PGE  I         P  PDS    G  G+PG    PG+PG  G      I C +    
Sbjct: 418 LPGEAGI---------PGRPDSA--PGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVG--- 463

Query: 313 SPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTG 372
           +P    +   V     R  +  +G+    A  E  P  PP PP    G  G   D+ + G
Sbjct: 464 NPGPQGIKGKVGPPGGRGPKGEKGNEGLCAC-EPGPMGPPGPPGLP-GRQGSKGDLGLPG 521

Query: 373 VVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAP 432
            +         GTK              +P PPG          +GPP  P     +  P
Sbjct: 522 WL---------GTKG-------------DPGPPGA---------EGPPGLPGKHGASGPP 550

Query: 433 GPDDAEG 439
           G   A+G
Sbjct: 551 GNKGAKG 557



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 13/27 (48%), Positives = 14/27 (51%)

Query: 413 NRGPDGPPEPPPADSPATAPGPDDAEG 439
           +RGP GPP P     P  APGP    G
Sbjct: 63  SRGPPGPPGPQGPIGPLGAPGPIGLSG 89


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 74/306 (24%), Positives = 106/306 (34%), Gaps = 58/306 (18%)

Query: 139 DPTKAPPDPGGRE-------GPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYP 191
           D + A  + G +E        P A +E PA+AG      S AE     E  AA A ++  
Sbjct: 44  DASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKG---EPAAAAAPEAGA 100

Query: 192 RPTTP-APVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLR--- 247
            P    AP    +AE G P    G    +     S  AE  A      ++P  K  R   
Sbjct: 101 SPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSF 160

Query: 248 KEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCD 307
           K+     G      +F+ +        ++  P+  GG+   A     G  A A +     
Sbjct: 161 KKSFKLSG-----FSFKKNKKEAGEGGEAEAPAAEGGKDEAA----GGAAAAAAEAGAAS 211

Query: 308 LYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVD 367
             Q  +P  +A         A  +E + G  P  A+P++   AP  PPA D         
Sbjct: 212 GEQAAAPGEEA---------AAGEEGAAGGDPQEAKPQEAAVAPEKPPASD--------- 253

Query: 368 VVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPP--EPPPA 425
              T   +E         +  K E    + +  E P           GP  PP  E  PA
Sbjct: 254 --ETKAAEE-----PSKVEEKKAEEAGASAAACEAPSAA--------GPGAPPEQEAAPA 298

Query: 426 DSPATA 431
           + PA A
Sbjct: 299 EEPAAA 304


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 89/357 (24%), Positives = 112/357 (31%), Gaps = 88/357 (24%)

Query: 142  KAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVF 201
            + P  P G +G   A   P +AG                   A      P P+ P   V 
Sbjct: 894  QGPTGPPGAKGQEGAHGAPGAAGNP----------------GAPGHVGAPGPSGPPGSVG 937

Query: 202  VSAEQGGPAK-GVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPG------- 253
                +G P K G   E+ + G + S               P   G  K+  PG       
Sbjct: 938  APGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGL 997

Query: 254  PGP-------GEVRIAFRISNGREPRAPDSGLPS-----GGGGRPGCAYPGSPGPGARAK 301
            PGP       G+VR +   + G +    D G P      G  G PG    G PGP     
Sbjct: 998  PGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 1057

Query: 302  DKITCDLYQLIS-------PSRDALPSN-----VEFLLARADEASEGDSPAPARP--EDT 347
            DK +     L           RD  P N            +   S GD    A+    D 
Sbjct: 1058 DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC 1117

Query: 348  PPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQ 407
            PP PP  P    G  GF  D  V G        G++GT+  K E       P  P PPG 
Sbjct: 1118 PPGPPGLP----GLPGFKGDKGVPGKP------GREGTEGKKGE----AGPPGLPGPPGI 1163

Query: 408  LFFLQNR------------------------GPDGPPEPPPADSPATAPGPDDAEGT 440
                 ++                        GP G P PP AD  A A GP   +G+
Sbjct: 1164 AGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS 1220



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 83/326 (25%), Positives = 110/326 (33%), Gaps = 48/326 (14%)

Query: 144  PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVS 203
            P  P G  GPP     P S GE     +  +  +  E  +   L  +  P  P       
Sbjct: 1316 PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSP-GLPGFLGPRGPPGE---P 1371

Query: 204  AEQGGPAK-GVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIA 262
             E+G P K GV  +    G            F+ +R  P  KG +        PG+  I 
Sbjct: 1372 GEKGVPGKEGVPGKPGEPG------------FKGERGDPGIKGDKGPPGGKGQPGDPGIP 1419

Query: 263  FRISNGREPRAPDSGLPSGGG--GRPGCAYPGSPG-PGARAKDKITCDLYQLISPSRDA- 318
                 G        GLP   G  G PG   PG PG PG R +      L +LI       
Sbjct: 1420 GH--KGHTGLMGPQGLPGENGPVGPPGP--PGQPGFPGLRGESPSMETLRRLIQEELGKQ 1475

Query: 319  LPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARD-----CGASGFHVDVVVTGV 373
            L + + +LLA+         PA  +     P PP PP +D      G  G        G+
Sbjct: 1476 LETRLAYLLAQMP-------PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGL 1528

Query: 374  VDECIFFGKDGTKNVKEETVCLTVS-------PEEPPPPGQLFFLQNRGPDGPPEPPPAD 426
                   G  G +  K +     V        P  P  PG+  + ++ G  G P P    
Sbjct: 1529 EGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKD-GLPGIPGPQGET 1587

Query: 427  SPA---TAPGPDDAEGTADTSLCRLY 449
             PA     PGP    G  D S C  +
Sbjct: 1588 GPAGHPGLPGPPGPPGQCDPSQCAYF 1613



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 82/331 (24%), Positives = 110/331 (33%), Gaps = 41/331 (12%)

Query: 16   PFGTYSQNQPR-PPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEV-PASQPAPLL 73
            P G      PR PP     P +  EPG    P    +  EN  P L   + P   P    
Sbjct: 1313 PTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 1372

Query: 74   SAAAAGDEGRVLLDTWYVIK-----PGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDS 128
                 G EG          K     PG   +K         GG  +     + GH G   
Sbjct: 1373 EKGVPGKEGVPGKPGEPGFKGERGDPGIKGDK------GPPGGKGQPGDPGIPGHKGHTG 1426

Query: 129  SKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQ 188
                +     +    PP P G+ G P    G + + E +  L   E+   +E R A  L 
Sbjct: 1427 LMGPQGLPGENGPVGPPGPPGQPGFPGL-RGESPSMETLRRLIQEELGKQLETRLAYLLA 1485

Query: 189  SYP---------RPTTPAPVVFVSAEQGGPAKG--VGSERRSGGGDCSRVAEAV---AHF 234
              P         RP  P P      + G P +   +G   R G G     +  +      
Sbjct: 1486 QMPPAYMKSSQGRPGPPGP----PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 1541

Query: 235  EAQRD-SPPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGS 293
             A+ D   P  GLR E  P   PG+        +G  P  P     +G  G PG   PG 
Sbjct: 1542 GAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGL-PGIPGPQGETGPAGHPG--LPGP 1598

Query: 294  PGPGARAKDKITCDLYQLISPSRDALPSNVE 324
            PGP  +  D   C  +  ++    A P NV+
Sbjct: 1599 PGPPGQC-DPSQCAYFASLA----ARPGNVK 1624



 Score = 36.6 bits (83), Expect = 0.068
 Identities = 59/213 (27%), Positives = 71/213 (33%), Gaps = 46/213 (21%)

Query: 252 PGPGPGEVRI----AFRISNGREPRAPDSGLPSGGGGRPG-CAYPGSPGP-GARAKDKIT 305
           PGP PG V        R   G      + GL  G  G+PG     G PGP G        
Sbjct: 577 PGP-PGRVGAPGLQGERGEKGTRGEKGERGL-DGFPGKPGDTGQQGRPGPSGVAGPQGEK 634

Query: 306 CDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDC------ 359
            D+     P    +P +V        E  +G+  AP  P     AP PP AR        
Sbjct: 635 GDVGPAGPPG---VPGSVV-----QQEGLKGEQGAPG-PRGHQGAPGPPGARGPIGPEGR 685

Query: 360 -------GASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPP------PG 406
                  G  G   D+   G+       G  G   V          P  P P      PG
Sbjct: 686 DGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGV----------PGPPGPGGSPGLPG 735

Query: 407 QLFFLQNRGPDGPPEPPPADSPATAPGPDDAEG 439
           ++ F    GP GP  PP  D P   PGP   +G
Sbjct: 736 EIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKG 768



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 86/375 (22%), Positives = 112/375 (29%), Gaps = 94/375 (25%)

Query: 108  QCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDV 167
            QC  G R +     G  GS  S+        DP      P G  GPP  +  P S G   
Sbjct: 1021 QCVKGDRGAP----GIPGSPGSRG-------DPGIGVAGPPGPSGPPGDKGSPGSRG--- 1066

Query: 168  DLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQG--GPAKGVGSERRSGGGDCS 225
                               L  +P P  PA         G  GP    G       GD +
Sbjct: 1067 -------------------LPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDIN 1107

Query: 226  RVAEAVAH--------------FEAQRDSPP------TKGLRKEERPGPGPGEVRIAFRI 265
             +A+ V +              F+  +  P       T+G + E  P   PG   IA   
Sbjct: 1108 LLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ 1167

Query: 266  SNGREPRAPDSGLPSGGGGRPGC----AYPGSPGP-------GARAKDKITCDLYQLISP 314
             +  E  A       G  G PG       PG+PGP       GA     I        SP
Sbjct: 1168 GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQG------SP 1221

Query: 315  SRDALPSNVEFLLARADEASEGDSPAPARP-------EDTPPAPPPPPARDCGASGFHVD 367
             ++  P              +G S  P  P        D  P PP  P +  G  G    
Sbjct: 1222 GKEGPPG------------PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGK-AGEPGLPGP 1268

Query: 368  VVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEE--PPPPGQLFFLQNRGPDGPPEPPPA 425
                G        G  G    + E+  + +  +E  P   G       +GP GP  PP  
Sbjct: 1269 EGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGK 1328

Query: 426  DSPATAPGPDDAEGT 440
            +    +PG     GT
Sbjct: 1329 NGSPGSPGEPGPSGT 1343



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 49/188 (26%), Positives = 55/188 (29%), Gaps = 35/188 (18%)

Query: 252 PGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQL 311
           PGP PG  R   +   G      + GLP   G R     PG PGP  R            
Sbjct: 538 PGP-PG--RDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRV----------- 583

Query: 312 ISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVT 371
                  L         R ++   G    P +P DT     P P+   G  G   DV   
Sbjct: 584 ---GAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDV--- 637

Query: 372 GVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATA 431
                    G  G   V    V       E   PG       RG  G P PP A  P   
Sbjct: 638 ---------GPAGPPGVPGSVVQQEGLKGEQGAPGP------RGHQGAPGPPGARGPIGP 682

Query: 432 PGPDDAEG 439
            G D   G
Sbjct: 683 EGRDGPPG 690



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 7/63 (11%)

Query: 381 GKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGT 440
           G+DG+K ++ E   L     EP  PG++     RGP GPP  P       APG     G 
Sbjct: 542 GRDGSKGMRGEPGELG----EPGLPGEVGM---RGPQGPPGLPGPPGRVGAPGLQGERGE 594

Query: 441 ADT 443
             T
Sbjct: 595 KGT 597



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 65/268 (24%), Positives = 87/268 (32%), Gaps = 58/268 (21%)

Query: 142 KAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYP---------- 191
           + P  P G  GPP     P   GE  +  +  E       +    L  +P          
Sbjct: 568 RGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE-------KGERGLDGFPGKPGDTGQQG 620

Query: 192 RPTTPAPVVFVSAEQG-----GPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKG- 245
           RP  P+ V     E+G     GP    GS  +  G    + A      +     P  +G 
Sbjct: 621 RP-GPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGP 679

Query: 246 LRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKIT 305
           +  E R GP PG   +  +  +   P  P      G  G PG   PG PGPG        
Sbjct: 680 IGPEGRDGP-PGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPG--VPGPPGPGG------- 729

Query: 306 CDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARP--EDTPPAPPPPPAR-----D 358
                  SP    LP  + F         +   P P  P  +D P  PP PP       +
Sbjct: 730 -------SP---GLPGEIGF-------PGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGE 772

Query: 359 CGASGFHVDVVVTGVVDECIFFGKDGTK 386
            G  G      + G + E    G+ G K
Sbjct: 773 RGEDGLPGKPGLRGEIGEQGLAGRPGEK 800



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 46/165 (27%), Positives = 55/165 (33%), Gaps = 47/165 (28%)

Query: 281 GGGGRPGC-AYPGSPGP-GARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDS 338
           G  G PG   + G+PGP GAR            I P     P  ++ L  +     +GD 
Sbjct: 657 GEQGAPGPRGHQGAPGPPGARGP----------IGPEGRDGPPGLQGLRGK-----KGDM 701

Query: 339 PAPARPE----DTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVC 394
             P  P       PP PP  P    G  G        G+  E  F GK G          
Sbjct: 702 GPPGIPGLLGLQGPPGPPGVPGPP-GPGGS------PGLPGEIGFPGKPGP--------- 745

Query: 395 LTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAEG 439
               P    PPG+       GP+GPP PP         G D   G
Sbjct: 746 ----PGPTGPPGK------DGPNGPPGPPGTKGEPGERGEDGLPG 780


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 82/320 (25%), Positives = 103/320 (32%), Gaps = 95/320 (29%)

Query: 142  KAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVF 201
            K  P P G  GPP +   P S GE+    +V                 +  P  P     
Sbjct: 815  KGEPGPRGLVGPPGSRGNPGSRGENGPTGAVG----------------FAGPQGPDGQPG 858

Query: 202  VSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGP-GPGEVR 260
            V  E G P +          GD                SP  +GL     PGP GP  V 
Sbjct: 859  VKGEPGEPGQK---------GDAG--------------SPGPQGLAGS--PGPHGPNGVP 893

Query: 261  IAFRISNGREPRAPD--SGLPSGGG--GRPGCAYPGSPGPGARAKDKITCDLYQLISPSR 316
                +  GR  + P   +G P   G  G PG A  G+PGP              L  P +
Sbjct: 894  ---GLKGGRGTQGPPGATGFPGSAGRVGPPGPA--GAPGPAG-----------PLGEPGK 937

Query: 317  DALPSNVEFLLARADEASEG--DSPAPARP-----------EDTPPAPPPPPARDCGASG 363
            +  P        R D  S G      PA P           ED  P P  PP    G +G
Sbjct: 938  EGPPG------LRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPG-PAGTTG 990

Query: 364  FHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPP 423
                V + G   E    G  G             +P +  P G      ++GP GP  PP
Sbjct: 991  QRGIVGMPGQRGERGMPGLPGPAG----------TPGKVGPTGAT---GDKGPPGPVGPP 1037

Query: 424  PADSPATAPGPDDAEGTADT 443
             ++ P   PGP+   G   T
Sbjct: 1038 GSNGPVGEPGPEGPAGNDGT 1057



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 80/347 (23%), Positives = 114/347 (32%), Gaps = 36/347 (10%)

Query: 110 GGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDL 169
           G      S   +G  G       R  + +D     P   G  GPP     P+  G D   
Sbjct: 132 GPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGH---PSHPGPDGLS 188

Query: 170 LSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGG-------G 222
              +  +A +++++ L  Q    P +  PV        GP    G + + GG       G
Sbjct: 189 RPFSAQMAGLDEKSGLGSQVGLMPGSVGPV--------GPRGPQGLQGQQGGAGPTGPPG 240

Query: 223 DCSRVAEAVAHFEAQRDSPPTK-GLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSG 281
           +               + PP K G   E      PGEV  A        P AP  GLP  
Sbjct: 241 EPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAP--GLPGL 298

Query: 282 GGGRPGCAYPGSPG----PGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGD 337
            G R      G  G    PG++ +   T  +  +       +P     L  +      G 
Sbjct: 299 KGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGA 358

Query: 338 SPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEET--VCL 395
              P +P    P   P      G+SGF  +  + G        G +G +  + ET     
Sbjct: 359 HGMPGKPGPMGPLGIP------GSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGP 412

Query: 396 TVSPEEPPPPGQLFFLQNRGPDGPPE---PPPADSPATAPGPDDAEG 439
             SP  P   G       +GP G P    PP +  P  +PGP  + G
Sbjct: 413 VGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTG 459



 Score = 36.6 bits (83), Expect = 0.068
 Identities = 88/314 (28%), Positives = 107/314 (34%), Gaps = 49/314 (15%)

Query: 142 KAPPDPGGREGP--PAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPT-TPAP 198
           K  P P G +GP  P  EEG      D   +     V    +R A   + +P     P P
Sbjct: 482 KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVG---ERGAPGNRGFPGSDGLPGP 538

Query: 199 VVFVSAEQG--GPAKGVGSERRSGG-GDCSRVAE-AVAHFEAQRDSPPTKGLRKEERPGP 254
                  QG  GP   VGS    G  GD  R  E  +        +P  +G   +  P  
Sbjct: 539 ----KGAQGERGP---VGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLG 591

Query: 255 GPGEV-RIAFRISNGREPRAPDSGLP-----SGGGGRPGCA-YPGSPGP-GARAKDKITC 306
            PGE  R     S G   +    GLP     SG  G+PG A   G PG  GA  KD    
Sbjct: 592 APGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGE-- 649

Query: 307 DLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHV 366
                + PS    P  +      A E  E   P P   +  P  P PP     G  G   
Sbjct: 650 -----VGPSGPVGPPGL------AGERGEQGPPGPTGFQGLPGPPGPP-----GEGGKPG 693

Query: 367 DVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPP-EPPPA 425
           D  V G        G  G +    E       P     PG+       GPDGP   P P+
Sbjct: 694 DQGVPGDPGAVGPLGPRGERGNPGERG----EPGITGLPGEKGMAGGHGPDGPKGSPGPS 749

Query: 426 DSPATAPGPDDAEG 439
            +P    GP   +G
Sbjct: 750 GTPGDT-GPPGLQG 762



 Score = 32.7 bits (73), Expect = 0.99
 Identities = 69/272 (25%), Positives = 94/272 (34%), Gaps = 52/272 (19%)

Query: 191 PRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSP-------PT 243
           P  T P  +  +  E+G    G    +   GG   + AE  A  +  R  P       P 
Sbjct: 752 PGDTGPPGLQGMPGERG--IAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPA 809

Query: 244 KGLRKEERPGP----GPGEVR--IAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPG 297
               ++  PGP    GP   R     R  NG       +G P G  G+PG    G PG  
Sbjct: 810 GPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAG-PQGPDGQPGVK--GEPGEP 866

Query: 298 ARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPAR 357
            +  D  +     L        P+ V  L  +    ++G   A   P       PP PA 
Sbjct: 867 GQKGDAGSPGPQGLAGSPGPHGPNGVPGL--KGGRGTQGPPGATGFPGSAGRVGPPGPA- 923

Query: 358 DCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPD 417
             GA G        G + E    GK+G   ++ +             PG    + +RGP 
Sbjct: 924 --GAPG------PAGPLGEP---GKEGPPGLRGD-------------PGSHGRVGDRGPA 959

Query: 418 GPPEPP-----PADSPATAPGPDDAEGTADTS 444
           GPP  P     P +     PGPD   G A T+
Sbjct: 960 GPPGGPGDKGDPGEDGQ--PGPDGPPGPAGTT 989


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 87/321 (27%), Positives = 110/321 (34%), Gaps = 83/321 (25%)

Query: 143  APPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPA--PVV 200
            +PPDP  RE            G    L S  + +      A  +L     PT P   P++
Sbjct: 1411 SPPDPARRE-----------LGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLL 1459

Query: 201  F-VSAEQGGPAKGVGSERRSGGGD-CSRVAEAVAHFE-AQRDSPPTKGLRKEERPGPG-- 255
              +  E   P  GV    RS   +   R+   V   E  Q  +P T G       GPG  
Sbjct: 1460 LQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVP 1519

Query: 256  PGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPS 315
            P   R +        P +P S   S   G P    P  P P    +D      +  + P 
Sbjct: 1520 PPSPRRSV-------PPSPTSPRASEENGLPLLVLP-PPAPSVDVED----GEFLFVEP- 1566

Query: 316  RDALPSNVEFLLARADEASEG-----------DSPAPARPEDTPPAPPP-----PPARDC 359
               LP  +EF  + + E  E            D+PAPA P   PP PPP     PP  D 
Sbjct: 1567 ---LPPPLEF--SNSFEKPESPLTPGPPHPLPDTPAPATP--LPPVPPPAVAAAPPTLDS 1619

Query: 360  GASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGP 419
             AS       +T    E           V   T   + +P +P PPG         P  P
Sbjct: 1620 TASS------LTSYDSE-----------VATLTQGASAAPGDPHPPG---------PPAP 1653

Query: 420  PEPPPADSPATAPGPDDAEGT 440
              P PA   A  PGPD   GT
Sbjct: 1654 AAPAPA---APQPGPDPPPGT 1671



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 88/359 (24%), Positives = 119/359 (33%), Gaps = 73/359 (20%)

Query: 20   YSQNQPRPPSAALKPSACPEPGGGA------EPDHGPAHSENTPPALATEVPASQPAPLL 73
            Y Q  PR  SAA+   A    G         + +  P      PPA +   PAS P P  
Sbjct: 1084 YFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPAS-PQPPP 1142

Query: 74   SAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKR 133
            + AA  ++  + + T  +  P  +            G  S+ SS + +            
Sbjct: 1143 AVAAPSEKNSIPIPTIIIKAPSTSSS----------GRSSQGSSTEAE------------ 1180

Query: 134  RRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRP 193
                  PT+  P  GG  G  +    PA +        V    + V   A+        P
Sbjct: 1181 -----PPTQPEPTGGGGGGGSSPSPAPAMS-------PVPPSPSPVPTPAS--------P 1220

Query: 194  TTPAPVVFVSAEQGGPAKGVGSERRSGG--GDCSRVAEAVAHFEAQRDSPPTKGLRKEER 251
            + PA + F S  Q G A  VG+ RR GG   +  R +      +A  +     GL     
Sbjct: 1221 SGPATLDFTS--QFGAAL-VGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAA 1277

Query: 252  PGPGPGEVRIAFRISNGREPRAP-------DSGLPSGGGGRPGCAYPGSPGPGARAK--- 301
            PGP    +R +  I  G     P        SG   GG G    AY G  G  A      
Sbjct: 1278 PGP---RLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLP 1334

Query: 302  -----DKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPP 355
                   +T       SP   AL +  E  L  + E      P P  P     APPP P
Sbjct: 1335 PRPLVHPLTGKALDPASPLGLALAAR-ERALKESSEGGGAPQPPPRPPSPRYEAPPPTP 1392



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 49/200 (24%), Positives = 70/200 (35%), Gaps = 35/200 (17%)

Query: 264  RISNGREP--RAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDALPS 321
            R++ G +P  R    G PS   G P  ++ GS G G  +        +QL  P R A  S
Sbjct: 1038 RLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQL--PPRAA--S 1093

Query: 322  NVEFLLARAD---------------EASEGDSPAPARPEDTPPAPPPPPARDCGASGFHV 366
               ++ AR+                E  +G    PA    +P +P PPPA    A     
Sbjct: 1094 AAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPA--VAAPSEKN 1151

Query: 367  DVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPA- 425
             + +  ++ +       G  +    T      P +P P G        G    P P PA 
Sbjct: 1152 SIPIPTIIIKAPSTSSSGRSSQGSSTE--AEPPTQPEPTG-----GGGGGGSSPSPAPAM 1204

Query: 426  ----DSPATAPGPDDAEGTA 441
                 SP+  P P    G A
Sbjct: 1205 SPVPPSPSPVPTPASPSGPA 1224



 Score = 32.7 bits (73), Expect = 0.99
 Identities = 77/308 (25%), Positives = 94/308 (30%), Gaps = 54/308 (17%)

Query: 138  LDPTKAPPDPGGREGPPAAEEGPASAGEDV-DLLSVAEMVALVEQRAALALQSYPRPTTP 196
            L  T AP  P     PPA    P +       L S    VA + Q A+ A      P  P
Sbjct: 1592 LPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPP 1651

Query: 197  APVV-FVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPG 255
            AP     +A Q GP    G++      D    ++   H      S  T      E  G  
Sbjct: 1652 APAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSD---HPLETISSASTLSSLSAEGGGSA 1708

Query: 256  PGEVRIAFRISNGREPR----APDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQL 311
             G       +++G E      A   G   GG   PG  YP                  QL
Sbjct: 1709 GGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPP-----------------QL 1751

Query: 312  ISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVT 371
            ++PS+         L  RA  AS G  P P+     P  P  P           V V   
Sbjct: 1752 MTPSK---------LRGRALGASGGLRPGPSGGLRDPVTPTSPT----------VSVTGA 1792

Query: 372  GVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPP-------GQLFFLQNRGPDGPPEPPP 424
            G           G          + V PE PP P        +       GP GPP PPP
Sbjct: 1793 GTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGP-GPP-PPP 1850

Query: 425  ADSPATAP 432
               P   P
Sbjct: 1851 LPGPLAQP 1858



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 50/187 (26%), Positives = 61/187 (32%), Gaps = 27/187 (14%)

Query: 271  PRAPDSG-LPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLAR 329
            P AP  G L    G  P   +PG   P   A  +          P R  LP +V FL   
Sbjct: 1450 PTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPE---------EPER--LPLHVRFLENC 1498

Query: 330  ADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVK 389
               A       P   ED P  PPP P R    S           +   +      + +V 
Sbjct: 1499 QPRAPVTSGRGPPS-EDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDV- 1556

Query: 390  EETVCLTVSPEEPPPPGQLFFLQNRGP--DGPPEP-----------PPADSPATAPGPDD 436
            E+   L V P  PP      F +   P   GPP P           PP   PA A  P  
Sbjct: 1557 EDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPT 1616

Query: 437  AEGTADT 443
             + TA +
Sbjct: 1617 LDSTASS 1623


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 84/327 (25%), Positives = 105/327 (32%), Gaps = 73/327 (22%)

Query: 142 KAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVF 201
           + P  P G +G   A   P +AG                   A      P P+ P   V 
Sbjct: 376 QGPTGPPGAKGQEGAHGAPGAAGNP----------------GAPGHVGAPGPSGPPGSVG 419

Query: 202 VSAEQGGPAK-GVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPG------- 253
               +G P K G   E+ + G + S               P   G  K+  PG       
Sbjct: 420 APGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGL 479

Query: 254 PGPGEVRIAFRISNGREPRAPDSGLPSGGGGR--PGCAYPGSPGPGARAKDKITCD---L 308
           PGP        +    +  AP  G+P   G R  PG    G PGP     DK +     L
Sbjct: 480 PGP--------LGTKGDRGAP--GIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 529

Query: 309 YQLISPSRDALPSNVEFLLARADEASEGDSPAPARP--EDTPPAPPPPPARDCGASGFHV 366
                P   A    +  LL      S GD    A+    D PP PP  P    G  GF  
Sbjct: 530 PGFPGPQGPAGRDGLSSLL------SPGDINLLAKDVCNDCPPGPPGLP----GLPGFKG 579

Query: 367 DVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLF------------FLQNR 414
           D  V G        G++GT+  K E       P  P PPG                +  +
Sbjct: 580 DKGVPGKP------GREGTEGKKGEAG----PPGLPGPPGIAGPQGSQGERGADGEVGQK 629

Query: 415 GPDGPPEPPPADSPATAPGPDDAEGTA 441
           G  G P  P    P   PGP  A+G A
Sbjct: 630 GDQGHPGVPGFMGPPGNPGPPGADGIA 656



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 83/326 (25%), Positives = 110/326 (33%), Gaps = 48/326 (14%)

Query: 144  PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVS 203
            P  P G  GPP     P S GE     +  +  +  E  +   L  +  P  P       
Sbjct: 763  PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSP-GLPGFLGPRGPPGE---P 818

Query: 204  AEQGGPAK-GVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIA 262
             E+G P K GV  +    G            F+ +R  P  KG +        PG+  I 
Sbjct: 819  GEKGVPGKEGVPGKPGEPG------------FKGERGDPGIKGDKGPPGGKGQPGDPGIP 866

Query: 263  FRISNGREPRAPDSGLPSGGG--GRPGCAYPGSPG-PGARAKDKITCDLYQLISPSRDA- 318
                 G        GLP   G  G PG   PG PG PG R +      L +LI       
Sbjct: 867  GH--KGHTGLMGPQGLPGENGPVGPPGP--PGQPGFPGLRGESPSMETLRRLIQEELGKQ 922

Query: 319  LPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARD-----CGASGFHVDVVVTGV 373
            L + + +LLA+         PA  +     P PP PP +D      G  G        G+
Sbjct: 923  LETRLAYLLAQMP-------PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGL 975

Query: 374  VDECIFFGKDGTKNVKEETVCLTVS-------PEEPPPPGQLFFLQNRGPDGPPEPPPAD 426
                   G  G +  K +     V        P  P  PG+  + ++ G  G P P    
Sbjct: 976  EGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKD-GLPGIPGPQGET 1034

Query: 427  SPA---TAPGPDDAEGTADTSLCRLY 449
             PA     PGP    G  D S C  +
Sbjct: 1035 GPAGHPGLPGPPGPPGQCDPSQCAYF 1060



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 82/331 (24%), Positives = 110/331 (33%), Gaps = 41/331 (12%)

Query: 16   PFGTYSQNQPR-PPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEV-PASQPAPLL 73
            P G      PR PP     P +  EPG    P    +  EN  P L   + P   P    
Sbjct: 760  PTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 819

Query: 74   SAAAAGDEGRVLLDTWYVIK-----PGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDS 128
                 G EG          K     PG   +K         GG  +     + GH G   
Sbjct: 820  EKGVPGKEGVPGKPGEPGFKGERGDPGIKGDK------GPPGGKGQPGDPGIPGHKGHTG 873

Query: 129  SKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQ 188
                +     +    PP P G+ G P    G + + E +  L   E+   +E R A  L 
Sbjct: 874  LMGPQGLPGENGPVGPPGPPGQPGFPGL-RGESPSMETLRRLIQEELGKQLETRLAYLLA 932

Query: 189  SYP---------RPTTPAPVVFVSAEQGGPAKG--VGSERRSGGGDCSRVAEAV---AHF 234
              P         RP  P P      + G P +   +G   R G G     +  +      
Sbjct: 933  QMPPAYMKSSQGRPGPPGP----PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 988

Query: 235  EAQRD-SPPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGS 293
             A+ D   P  GLR E  P   PG+        +G  P  P     +G  G PG   PG 
Sbjct: 989  GAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGL-PGIPGPQGETGPAGHPG--LPGP 1045

Query: 294  PGPGARAKDKITCDLYQLISPSRDALPSNVE 324
            PGP  +  D   C  +  ++    A P NV+
Sbjct: 1046 PGPPGQC-DPSQCAYFASLA----ARPGNVK 1071



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 76/342 (22%), Positives = 100/342 (29%), Gaps = 94/342 (27%)

Query: 139 DPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAP 198
           DP      P G  GPP  +  P S G                      L  +P P     
Sbjct: 503 DPGIGVAGPPGPSGPPGDKGSPGSRG----------------------LPGFPGPQ---- 536

Query: 199 VVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAH--------------FEAQRDSPP-- 242
                    GPA   G       GD + +A+ V +              F+  +  P   
Sbjct: 537 ---------GPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP 587

Query: 243 ----TKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGC----AYPGSP 294
               T+G + E  P   PG   IA    +  E  A       G  G PG       PG+P
Sbjct: 588 GREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP 647

Query: 295 GP-------GARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARP--- 344
           GP       GA     I        SP ++  P              +G S  P  P   
Sbjct: 648 GPPGADGIAGAAGPPGIQG------SPGKEGPPG------------PQGPSGLPGIPGEE 689

Query: 345 ----EDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPE 400
                D  P PP  P +  G  G        G        G  G    + E+  + +  +
Sbjct: 690 GKEGRDGKPGPPGEPGK-AGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ 748

Query: 401 E--PPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGT 440
           E  P   G       +GP GP  PP  +    +PG     GT
Sbjct: 749 EGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT 790


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 101/432 (23%), Positives = 126/432 (29%), Gaps = 100/432 (23%)

Query: 25   PRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALA----TEVPASQPAPLLSAAAAGD 80
            P P      P    EPGG  E        E  PP +A       PA  P P       G 
Sbjct: 806  PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGS 865

Query: 81   EGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDP 140
             G           PG      A  +    G           G  G D             
Sbjct: 866  PG----------GPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGN----- 910

Query: 141  TKAPPDPG-----------GREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQS 189
            T AP  PG           G +G P A+  P + G     L +A    +   R       
Sbjct: 911  TGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGP----LGIA---GITGARGLAGPPG 963

Query: 190  YPRPTTPAPVVFVSAEQGGP-AKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRK 248
             P P        V  E G P A G+  ER   G          A    +  +P + GL  
Sbjct: 964  MPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023

Query: 249  EERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDL 308
             +    G G+     R  NG  P AP      G  G PG   PG  GP  ++ D+     
Sbjct: 1024 RDGSPGGKGD-----RGENG-SPGAP------GAPGHPG--PPGPVGPAGKSGDR----- 1064

Query: 309  YQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDV 368
                                 +  A    +P PA     P   P  P  D G +G   + 
Sbjct: 1065 -------------------GESGPAGPAGAPGPAGSRGAP--GPQGPRGDKGETG---ER 1100

Query: 369  VVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQN------RGPDGPPEP 422
               G+     F G  G             +P  P P GQ   + +      RGP GP  P
Sbjct: 1101 GAAGIKGHRGFPGNPG-------------APGSPGPAGQQGAIGSPGPAGPRGPVGPSGP 1147

Query: 423  PPADSPATAPGP 434
            P  D  +  PGP
Sbjct: 1148 PGKDGTSGHPGP 1159



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 83/327 (25%), Positives = 103/327 (31%), Gaps = 70/327 (21%)

Query: 144  PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVS 203
            PP P G  G P     P   GE                R A   +    P   A     S
Sbjct: 805  PPGPAGFPGAPGQNGEPGGKGE----------------RGAPGEKGEGGPPGVAGPPGGS 848

Query: 204  AEQGGPA-KGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGP-----GPG 257
               G P  +GV  ER S GG         A F   R  P   G      PGP      PG
Sbjct: 849  GPAGPPGPQGVKGERGSPGGP------GAAGFPGARGLPGPPG--SNGNPGPPGPSGSPG 900

Query: 258  EVRIAFRISNGREPRAPDSGLPSGGGGRPG-------CAYPGSPGP-------GARAKDK 303
            +        N   P +P    P G  G+PG          PG+PGP       GAR    
Sbjct: 901  KDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARG--- 957

Query: 304  ITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASG 363
                   L  P     P       +   +  +G+S  P     +    PP P    G +G
Sbjct: 958  -------LAGPPGMPGPRG-----SPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAG 1005

Query: 364  FHVDVVVTGVVDECIFFGKDGTKNVKEE-----TVCLTVSPEEPPPPGQLFFLQ---NRG 415
               +    G        G+DG+   K +     +     +P  P PPG +       +RG
Sbjct: 1006 TAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRG 1065

Query: 416  PDGPPEPPPADSPA---TAPGPDDAEG 439
              GP  P  A  PA    APGP    G
Sbjct: 1066 ESGPAGPAGAPGPAGSRGAPGPQGPRG 1092



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 109/434 (25%), Positives = 138/434 (31%), Gaps = 64/434 (14%)

Query: 21  SQNQPRPPSAALKPSACPEPGG-GAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAG 79
           S  QP PP     P     PG  GA+ + GPA S   P +        +P P   A A G
Sbjct: 328 SDGQPGPPGP---PGTAGFPGSPGAKGEVGPAGS---PGSNGAPGQRGEPGPQGHAGAQG 381

Query: 80  DEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLD 139
             G   ++      PG   E     +    G           G  G+   +        +
Sbjct: 382 PPGPPGING----SPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKN 437

Query: 140 PTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPV 199
             K  P P G  G       P + GED    S  E  A     AA   +  P    PA  
Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAA-GERGAPGFRGPAGP 496

Query: 200 VFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPT-KGLRKEERPGPGPGE 258
             +  E     KG   ER + G    R A      E  RD  P   G+R       GPG 
Sbjct: 497 NGIPGE-----KGPAGERGAPGPAGPRGAAG----EPGRDGVPGGPGMRGMPGSPGGPG- 546

Query: 259 VRIAFRISNGREPRAPDSGLPSGGGGRPGCAYP-GSPG----PGARAKDKITCDLYQLIS 313
                  S+G+ P  P S   SG  G PG + P G PG    PG +  D          +
Sbjct: 547 -------SDGK-PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDG---------A 589

Query: 314 PSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPAR------DCGASGFHVD 367
           P ++           R      G    P +  +T P  PP P        D G  G    
Sbjct: 590 PGKNG---------ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGL 640

Query: 368 VVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADS 427
             + G        GK G    K +      +P  P   G       RGP G    P    
Sbjct: 641 QGLPGTGGPPGENGKPGEPGPKGDAG----APGAPGGKGDAGAPGERGPPGLAGAPGLRG 696

Query: 428 PATAPGPDDAEGTA 441
            A  PGP+  +G A
Sbjct: 697 GAGPPGPEGGKGAA 710



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 91/369 (24%), Positives = 112/369 (30%), Gaps = 79/369 (21%)

Query: 14   PRPFGTYSQNQPRPPSAALKPSACPEPG-GGAEPDHGPAHSENTPPALATEVPASQPAPL 72
            P P G  S  +  PP  A    A   PG  G + D G    + +P A   + P   P PL
Sbjct: 893  PGPSG--SPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGA---QGPPGAPGPL 947

Query: 73   LSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAK 132
              A   G  G           PG              G         VKG  G   +   
Sbjct: 948  GIAGITGARG-------LAGPPGMP------------GPRGSPGPQGVKGESGKPGANGL 988

Query: 133  RRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRA--ALALQSY 190
               R     +  P   G  G P  +  P S G      S        E  +  A     +
Sbjct: 989  SGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGH 1048

Query: 191  PRPTTPAPVVFVSAEQG--GPAKGVGSERRSGG----------GDCSRVAE-AVAHFEAQ 237
            P P  P      S ++G  GPA   G+   +G           GD     E   A  +  
Sbjct: 1049 PGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGH 1108

Query: 238  RDSPPTKGLRKEERPG-PGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCA-YPGSPG 295
            R  P   G      PG PGP   + A        PR P    PSG  G+ G + +PG  G
Sbjct: 1109 RGFPGNPGA-----PGSPGPAGQQGAIGSPGPAGPRGPVG--PSGPPGKDGTSGHPGPIG 1161

Query: 296  P-GARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPP 354
            P G R                             R +  SEG    P +P   PP PP  
Sbjct: 1162 PPGPRGN---------------------------RGERGSEGSPGHPGQPG--PPGPPGA 1192

Query: 355  PARDCGASG 363
            P   CG  G
Sbjct: 1193 PGPCCGGVG 1201



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 55/214 (25%), Positives = 65/214 (30%), Gaps = 33/214 (15%)

Query: 241 PPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYP----GSPGP 296
           P   G + E+     PGE           E  AP    P+G  G PG   P    G+PGP
Sbjct: 455 PGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGP 514

Query: 297 -GARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARP----EDTPPAP 351
            G R              P RD +P               G    P  P    E   P P
Sbjct: 515 AGPRGAAG---------EPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGP 565

Query: 352 PPP--PARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLF 409
           P P  P    G  GF       G        GK+G +            P    PPG+  
Sbjct: 566 PGPSGPRGQPGVMGFPGPKGNDGAP------GKNGERGGPG-------GPGPQGPPGKNG 612

Query: 410 FLQNRGPDGPPEPPPADSPATAPGPDDAEGTADT 443
               +GP GP  P         PGP   +G   T
Sbjct: 613 ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGT 646



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 84/351 (23%), Positives = 105/351 (29%), Gaps = 78/351 (22%)

Query: 110 GGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDL 169
           GG         KG  G    + +     +   K      G  G P A   P +AGE    
Sbjct: 429 GGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGE---- 484

Query: 170 LSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAE 229
                       R A   +    P         + E+G P  G    R + G        
Sbjct: 485 ------------RGAPGFRGPAGPNGIPGEKGPAGERGAP--GPAGPRGAAG-------- 522

Query: 230 AVAHFEAQRDS-PPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGC 288
                E  RD  P   G+R       GPG        S+G+ P  P S   SG  G PG 
Sbjct: 523 -----EPGRDGVPGGPGMRGMPGSPGGPG--------SDGK-PGPPGSQGESGRPGPPGP 568

Query: 289 AYP-GSPG----PGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPAR 343
           + P G PG    PG +  D          +P ++           R      G    P +
Sbjct: 569 SGPRGQPGVMGFPGPKGNDG---------APGKNG---------ERGGPGGPGPQGPPGK 610

Query: 344 PEDTPPAPPPPPA------RDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTV 397
             +T P  PP P        D G  G      + G        GK G    K +      
Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA 670

Query: 398 --------SPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGT 440
                   +P E  PPG       RG  GPP P      A  PGP  A GT
Sbjct: 671 PGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGT 721



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 65/244 (26%), Positives = 81/244 (33%), Gaps = 48/244 (19%)

Query: 208 GPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISN 267
           GPA   G +   G      +A         R SP  +G      P   PG         N
Sbjct: 771 GPAGQPGDKGEGGAPGLPGIA-------GPRGSPGERGETGPPGPAGFPGAPG-----QN 818

Query: 268 GREPRAPDSGLPS--GGGGRPGCAYP-------GSPGPGARAKDKITCDLYQLISPSRDA 318
           G      + G P   G GG PG A P       G PGP     ++         SP    
Sbjct: 819 GEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERG--------SPGG-- 868

Query: 319 LPSNVEFLLARADEASEGDS--PAPARPEDTPPAPPPP-PARDCGASGFHVDVVVTGVVD 375
            P    F  AR      G +  P P  P  +P    PP PA + GA G      V+G   
Sbjct: 869 -PGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPG---SPGVSGPKG 924

Query: 376 ECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPD 435
           +    G+ G+   +         P  P P G       RG  GPP  P    P  +PGP 
Sbjct: 925 DAGQPGEKGSPGAQGP-------PGAPGPLGIAGITGARGLAGPPGMP---GPRGSPGPQ 974

Query: 436 DAEG 439
             +G
Sbjct: 975 GVKG 978



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 71/303 (23%), Positives = 90/303 (29%), Gaps = 65/303 (21%)

Query: 144 PPDPG--GREGPPAAEE----GPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPA 197
           P  PG  G  GPP   E    GP +     D   V   VA+        L  YP P  P 
Sbjct: 126 PGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVG------GLAGYPGPAGPP 179

Query: 198 PVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPG 257
                    G P        +   G+  +   +          P   G      P    G
Sbjct: 180 GPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPS--------GPPGPPGAIGPSGPAGKDG 231

Query: 258 EVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPG-PGARAKDKITCDLYQLISP-- 314
           E        +GR  R  + GLP   G +     PG PG  G R  D    +  +  +P  
Sbjct: 232 E--------SGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGL 283

Query: 315 -SRDALPSNVEFLLARADEASEGDSPAP-------------ARPEDTPPAPPPPPARDCG 360
              + LP             + G+   P             AR  D  P PP PP    G
Sbjct: 284 KGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPP----G 339

Query: 361 ASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPP 420
            +GF       G V      G +G    +           EP P G      + G  GPP
Sbjct: 340 TAGFPGSPGAKGEVGPAGSPGSNGAPGQR----------GEPGPQG------HAGAQGPP 383

Query: 421 EPP 423
            PP
Sbjct: 384 GPP 386



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 77/318 (24%), Positives = 102/318 (32%), Gaps = 45/318 (14%)

Query: 144 PPDPGGREG------PPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPA 197
           PP P G +G      PP     P   G   D  + A      +  A    +  P     A
Sbjct: 634 PPGPQGLQGLPGTGGPPGENGKPGEPGPKGD--AGAPGAPGGKGDAGAPGERGPPGLAGA 691

Query: 198 PVVFVSAEQGGPAKGVGSERRSG--GGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPG 255
           P +   A   GP  G G+    G  G   +   + +        SP  KG + E  PG G
Sbjct: 692 PGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE--PG-G 748

Query: 256 PGEVRIAFRISNGREPRAPDSGL-PSGGGGRPGC----AYPGSPG-------PGARAKDK 303
           PG    A  +     PR P   + P G  G+PG       PG PG       PG R +  
Sbjct: 749 PG----ADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETG 804

Query: 304 ITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASG 363
                    +P ++  P       A  ++   G       P  + PA PP P    G  G
Sbjct: 805 PPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERG 864

Query: 364 FHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPP 423
                   G        G  G+            +P  P P G      + G DGPP P 
Sbjct: 865 SPGGPGAAGFPGARGLPGPPGSNG----------NPGPPGPSG------SPGKDGPPGPA 908

Query: 424 PADSPATAPGPDDAEGTA 441
                  +PG    +G A
Sbjct: 909 GNTGAPGSPGVSGPKGDA 926



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 101/442 (22%), Positives = 122/442 (27%), Gaps = 80/442 (18%)

Query: 25  PRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRV 84
           P PP  +  P +   PG    P        + PP      P     P   A   G+ GR 
Sbjct: 182 PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPG-----PPGAIGPSGPAGKDGESGR- 235

Query: 85  LLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAP 144
                    PG   E+         G         +KGH G D    ++        K  
Sbjct: 236 ---------PGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGE 286

Query: 145 PDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSA 204
               G  G P    GP  A  +     +           A      P P  P        
Sbjct: 287 NGLPGENGAP-GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPG 345

Query: 205 EQG-----GPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKG-LRKEERPGP---- 254
             G     GPA   GS    G                QR  P  +G    +  PGP    
Sbjct: 346 SPGAKGEVGPAGSPGSNGAPG----------------QRGEPGPQGHAGAQGPPGPPGIN 389

Query: 255 ---------GPGEVRIAFRISNGREPRAP--DSGLPS--GGGGRPG-CAYPGSPGP-GAR 299
                    GP  +  A  +   R P  P   +G P   GG G PG     G PGP G R
Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGER 449

Query: 300 AKDKITCDLYQLISPSRDALPS--NVEFLLARADEASEGDSPAPARPEDTPPAPPPPPAR 357
            +  I           +D  P       L   A E        PA P   P      PA 
Sbjct: 450 GEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIP--GEKGPAG 507

Query: 358 DCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPD 417
           + GA G        G   E    G+DG              P  P   G        G D
Sbjct: 508 ERGAPG---PAGPRGAAGEP---GRDGV-------------PGGPGMRGMPGSPGGPGSD 548

Query: 418 GPPEPPPADSPATAPGPDDAEG 439
           G P PP +   +  PGP    G
Sbjct: 549 GKPGPPGSQGESGRPGPPGPSG 570


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 90/371 (24%), Positives = 113/371 (30%), Gaps = 88/371 (23%)

Query: 94   PGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGP 153
            PG   EK A  VA + G   +      +G  G+     K   +       PP P G  GP
Sbjct: 873  PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 932

Query: 154  ---------PAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSA 204
                     P  +  P   G+D        +     QR     Q    P  P  VV    
Sbjct: 933  QGPQGPVGFPGPKGPPGPPGKD-------GLPGHPGQRGETGFQGKTGPPGPGGVV---- 981

Query: 205  EQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFR 264
               GP    G     G                +R  P          PGP PGE  +   
Sbjct: 982  ---GPQGPTGETGPIG----------------ERGHPGP--------PGP-PGEQGLPG- 1012

Query: 265  ISNGREPRAPDSGLPSGGGGRPGCA----YPGSPG-PGARAKDKITCDLYQLISPSRDAL 319
             + G+E    D G P G  G+ G A    +PG  G PGA+    +         P     
Sbjct: 1013 -AAGKEGAKGDPG-PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1070

Query: 320  PSNVEFLLARADEASEGDSPAPARPEDTPPAPPPP-----------PARDCGASGFHVDV 368
            P        R    + G    P RP   P  PP P           P    G  G    V
Sbjct: 1071 PGE------RGSAGTAGPIGLPGRP--GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1122

Query: 369  VVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSP 428
             + G        G+DG K              E   PGQ     ++G +GPP PP    P
Sbjct: 1123 GLPGPAGPAGSPGEDGDKG-------------EIGEPGQKGSKGDKGENGPPGPPGLQGP 1169

Query: 429  ATAPGPDDAEG 439
              APG    +G
Sbjct: 1170 VGAPGIAGGDG 1180



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 99/437 (22%), Positives = 134/437 (30%), Gaps = 78/437 (17%)

Query: 14   PRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLL 73
            P P G      PR    A  P+  P P G +  D  P       P    + P   P P  
Sbjct: 888  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ-GPQGPVGFPGPKG 946

Query: 74   SAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKR 133
                 G +G           PG+  ++       + G       +  +G  G      +R
Sbjct: 947  PPGPPGKDGL----------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 996

Query: 134  RRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRP 193
                      PP P G +G P A     + G+                      Q     
Sbjct: 997  GH------PGPPGPPGEQGLPGAAGKEGAKGDP-------------------GPQGISGK 1031

Query: 194  TTPAPVVFVSAEQGGPAKGVGSERRSG--GGDCSRVAEAVAHFEAQRDSPPTKG-LRKEE 250
              PA +     E+G P    G++   G  GG+  +          +R S  T G +    
Sbjct: 1032 DGPAGLRGFPGERGLP----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1087

Query: 251  RPGP-GPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYP-GSPGPGARAKDKITCDL 308
            RPGP GP             E  AP    P G  GR G   P G PGP   A        
Sbjct: 1088 RPGPQGPP--------GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG------- 1132

Query: 309  YQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDV 368
                SP  D     +        + S+GD     + E+ PP PP       GA G     
Sbjct: 1133 ----SPGEDGDKGEIG---EPGQKGSKGD-----KGENGPPGPPGLQG-PVGAPGIAGGD 1179

Query: 369  VVTGVVDECIFFGKDGTKNVK-----EETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPP 423
               G   +   FG+ G +  +        + L   P  P   G+   +   GP GPP P 
Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1239

Query: 424  PADSPATAPGPDDAEGT 440
                P  A GP    G+
Sbjct: 1240 GPQGPNGADGPQGPPGS 1256



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 78/309 (25%), Positives = 98/309 (31%), Gaps = 84/309 (27%)

Query: 140 PTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPV 199
           PT  P DPG R GPP     P + G                            P  P  +
Sbjct: 473 PTGPPGDPGDR-GPPGRPGLPGADG---------------------------LPGPPGTM 504

Query: 200 VFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFE----AQRDSPPTKGLRKEERPGPG 255
           + +    GG           G    ++ A+A A  +    A R  P   GL     P  G
Sbjct: 505 LMLPFRYGGDGS-------KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGG 557

Query: 256 PGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPG-PGARAKDKITCDLYQLISP 314
           PG        S+G +  + D G P G  G  G   PG  G PG R +            P
Sbjct: 558 PG--------SSGAKGESGDPG-PQGPRGVQGP--PGPTGKPGKRGR------------P 594

Query: 315 SRDALPSNVEFLLARADEASEGDSPAPA----RPEDTPPAPPPPPARDCGASGFHVDVVV 370
             D          A+ D   +G    P     R E  P  PP PP  D G  G   ++  
Sbjct: 595 GADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD-GMRGEDGEIGP 653

Query: 371 TGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPAT 430
            G+  E    G  G +           +P  P  PG        G DGPP P     P  
Sbjct: 654 RGLPGEAGPRGLLGPRG----------TPGAPGQPGMA------GVDGPPGPKGNMGPQG 697

Query: 431 APGPDDAEG 439
            PGP   +G
Sbjct: 698 EPGPPGQQG 706



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 100/421 (23%), Positives = 128/421 (30%), Gaps = 103/421 (24%)

Query: 34   PSACPEPGG--GAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLLDTWYV 91
            P   P P G  GA  + GP            + P   P P   A + G++G    D   +
Sbjct: 1091 PQGPPGPAGEKGAPGEKGPQGPAGRD---GVQGPVGLPGPAGPAGSPGEDG----DKGEI 1143

Query: 92   IKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKA-------- 143
             +PG    K         G       +   G  G D     R ++ +   K         
Sbjct: 1144 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1203

Query: 144  -PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFV 202
             PP P G +G P     P   GE+ D+               +     P P  P      
Sbjct: 1204 GPPGPIGLQGLPGP---PGEKGENGDV-------------GPMGPPGPPGPRGPQGPNGA 1247

Query: 203  SAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTK---GLRKEERPGPGPGEV 259
               QG P    GS    GG     V E     EA    PP +   G  K ER   G    
Sbjct: 1248 DGPQGPP----GSVGSVGG-----VGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG---- 1294

Query: 260  RIAFRISNGREPRAPDSGLPSGGGGRPGCAYP-GSPGPGARAKDKITCDLYQLISPSRDA 318
                      E   P +  P G  G PG   P G+PGP     D           P  + 
Sbjct: 1295 ----------EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP---------GPPGEP 1335

Query: 319  LPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECI 378
             P+  + +    D+  +GD   P  P  +  A PP P    G  G        G      
Sbjct: 1336 GPAGQDGV--GGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG------AAGAE---- 1383

Query: 379  FFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAE 438
              G+ G K  K E            PPG+       GP GP        PA  PGP+   
Sbjct: 1384 --GRQGEKGAKGEAGA-------EGPPGKT------GPVGP------QGPAGKPGPEGLR 1422

Query: 439  G 439
            G
Sbjct: 1423 G 1423



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 74/322 (22%), Positives = 96/322 (29%), Gaps = 47/322 (14%)

Query: 144  PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVS 203
            PP P G +GP  A+ GP      V        V  V ++        P P   A V    
Sbjct: 1235 PPGPRGPQGPNGAD-GPQGPPGSVG------SVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1287

Query: 204  AEQG-----GPAKGVGSERRSG--GGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGP 256
             E+G     GP    G     G  G D  +       F      P   G   ++  G   
Sbjct: 1288 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK 1347

Query: 257  GEVRIAFRISNGREPRAPDSGLPSGGGGRPGC----AYPGSPGPGARAKDKITCDLYQLI 312
            GE           +P  P    PSG  G PG       PG+ G   R  +K         
Sbjct: 1348 GE---------DGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1398

Query: 313  SPSRDALPSNVEFLLARADEASEGDSPAP--------ARPEDTPPAPPPPPAR-----DC 359
             P     P   +    +         P P        A  +D PP P  PP       D 
Sbjct: 1399 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1458

Query: 360  GASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGP 419
            G+ G      + G++      G+ G +        L  +   P   G        GP GP
Sbjct: 1459 GSKGEKGHPGLIGLIGPPGEQGEKGDRG-------LPGTQGSPGAKGDGGIPGPAGPLGP 1511

Query: 420  PEPPPADSPATAPGPDDAEGTA 441
            P PP    P    G   + G A
Sbjct: 1512 PGPPGLPGPQGPKGNKGSTGPA 1533


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 90/371 (24%), Positives = 113/371 (30%), Gaps = 88/371 (23%)

Query: 94   PGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGP 153
            PG   EK A  VA + G   +      +G  G+     K   +       PP P G  GP
Sbjct: 822  PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 881

Query: 154  ---------PAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSA 204
                     P  +  P   G+D        +     QR     Q    P  P  VV    
Sbjct: 882  QGPQGPVGFPGPKGPPGPPGKD-------GLPGHPGQRGETGFQGKTGPPGPGGVV---- 930

Query: 205  EQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFR 264
               GP    G     G                +R  P          PGP PGE  +   
Sbjct: 931  ---GPQGPTGETGPIG----------------ERGHPGP--------PGP-PGEQGLPG- 961

Query: 265  ISNGREPRAPDSGLPSGGGGRPGCA----YPGSPG-PGARAKDKITCDLYQLISPSRDAL 319
             + G+E    D G P G  G+ G A    +PG  G PGA+    +         P     
Sbjct: 962  -AAGKEGAKGDPG-PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1019

Query: 320  PSNVEFLLARADEASEGDSPAPARPEDTPPAPPPP-----------PARDCGASGFHVDV 368
            P        R    + G    P RP   P  PP P           P    G  G    V
Sbjct: 1020 PGE------RGSAGTAGPIGLPGRP--GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1071

Query: 369  VVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSP 428
             + G        G+DG K              E   PGQ     ++G +GPP PP    P
Sbjct: 1072 GLPGPAGPAGSPGEDGDKG-------------EIGEPGQKGSKGDKGENGPPGPPGLQGP 1118

Query: 429  ATAPGPDDAEG 439
              APG    +G
Sbjct: 1119 VGAPGIAGGDG 1129



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 99/437 (22%), Positives = 134/437 (30%), Gaps = 78/437 (17%)

Query: 14   PRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLL 73
            P P G      PR    A  P+  P P G +  D  P       P    + P   P P  
Sbjct: 837  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ-GPQGPVGFPGPKG 895

Query: 74   SAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKR 133
                 G +G           PG+  ++       + G       +  +G  G      +R
Sbjct: 896  PPGPPGKDGL----------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 945

Query: 134  RRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRP 193
                      PP P G +G P A     + G+                      Q     
Sbjct: 946  GH------PGPPGPPGEQGLPGAAGKEGAKGDP-------------------GPQGISGK 980

Query: 194  TTPAPVVFVSAEQGGPAKGVGSERRSG--GGDCSRVAEAVAHFEAQRDSPPTKG-LRKEE 250
              PA +     E+G P    G++   G  GG+  +          +R S  T G +    
Sbjct: 981  DGPAGLRGFPGERGLP----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1036

Query: 251  RPGP-GPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYP-GSPGPGARAKDKITCDL 308
            RPGP GP             E  AP    P G  GR G   P G PGP   A        
Sbjct: 1037 RPGPQGPP--------GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG------- 1081

Query: 309  YQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDV 368
                SP  D     +        + S+GD     + E+ PP PP       GA G     
Sbjct: 1082 ----SPGEDGDKGEIG---EPGQKGSKGD-----KGENGPPGPPGLQG-PVGAPGIAGGD 1128

Query: 369  VVTGVVDECIFFGKDGTKNVK-----EETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPP 423
               G   +   FG+ G +  +        + L   P  P   G+   +   GP GPP P 
Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1188

Query: 424  PADSPATAPGPDDAEGT 440
                P  A GP    G+
Sbjct: 1189 GPQGPNGADGPQGPPGS 1205



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 78/309 (25%), Positives = 98/309 (31%), Gaps = 84/309 (27%)

Query: 140 PTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPV 199
           PT  P DPG R GPP     P + G                            P  P  +
Sbjct: 422 PTGPPGDPGDR-GPPGRPGLPGADG---------------------------LPGPPGTM 453

Query: 200 VFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFE----AQRDSPPTKGLRKEERPGPG 255
           + +    GG           G    ++ A+A A  +    A R  P   GL     P  G
Sbjct: 454 LMLPFRYGGDGS-------KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGG 506

Query: 256 PGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPG-PGARAKDKITCDLYQLISP 314
           PG        S+G +  + D G P G  G  G   PG  G PG R +            P
Sbjct: 507 PG--------SSGAKGESGDPG-PQGPRGVQGP--PGPTGKPGKRGR------------P 543

Query: 315 SRDALPSNVEFLLARADEASEGDSPAPA----RPEDTPPAPPPPPARDCGASGFHVDVVV 370
             D          A+ D   +G    P     R E  P  PP PP  D G  G   ++  
Sbjct: 544 GADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD-GMRGEDGEIGP 602

Query: 371 TGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPAT 430
            G+  E    G  G +           +P  P  PG        G DGPP P     P  
Sbjct: 603 RGLPGEAGPRGLLGPRG----------TPGAPGQPGMA------GVDGPPGPKGNMGPQG 646

Query: 431 APGPDDAEG 439
            PGP   +G
Sbjct: 647 EPGPPGQQG 655



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 100/421 (23%), Positives = 128/421 (30%), Gaps = 103/421 (24%)

Query: 34   PSACPEPGG--GAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLLDTWYV 91
            P   P P G  GA  + GP            + P   P P   A + G++G    D   +
Sbjct: 1040 PQGPPGPAGEKGAPGEKGPQGPAGRD---GVQGPVGLPGPAGPAGSPGEDG----DKGEI 1092

Query: 92   IKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKA-------- 143
             +PG    K         G       +   G  G D     R ++ +   K         
Sbjct: 1093 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1152

Query: 144  -PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFV 202
             PP P G +G P     P   GE+ D+               +     P P  P      
Sbjct: 1153 GPPGPIGLQGLPGP---PGEKGENGDV-------------GPMGPPGPPGPRGPQGPNGA 1196

Query: 203  SAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTK---GLRKEERPGPGPGEV 259
               QG P    GS    GG     V E     EA    PP +   G  K ER   G    
Sbjct: 1197 DGPQGPP----GSVGSVGG-----VGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG---- 1243

Query: 260  RIAFRISNGREPRAPDSGLPSGGGGRPGCAYP-GSPGPGARAKDKITCDLYQLISPSRDA 318
                      E   P +  P G  G PG   P G+PGP     D           P  + 
Sbjct: 1244 ----------EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP---------GPPGEP 1284

Query: 319  LPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECI 378
             P+  + +    D+  +GD   P  P  +  A PP P    G  G        G      
Sbjct: 1285 GPAGQDGV--GGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG------AAGAE---- 1332

Query: 379  FFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAE 438
              G+ G K  K E            PPG+       GP GP        PA  PGP+   
Sbjct: 1333 --GRQGEKGAKGEAGA-------EGPPGKT------GPVGP------QGPAGKPGPEGLR 1371

Query: 439  G 439
            G
Sbjct: 1372 G 1372



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 74/322 (22%), Positives = 96/322 (29%), Gaps = 47/322 (14%)

Query: 144  PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVS 203
            PP P G +GP  A+ GP      V        V  V ++        P P   A V    
Sbjct: 1184 PPGPRGPQGPNGAD-GPQGPPGSVG------SVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1236

Query: 204  AEQG-----GPAKGVGSERRSG--GGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGP 256
             E+G     GP    G     G  G D  +       F      P   G   ++  G   
Sbjct: 1237 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK 1296

Query: 257  GEVRIAFRISNGREPRAPDSGLPSGGGGRPGC----AYPGSPGPGARAKDKITCDLYQLI 312
            GE           +P  P    PSG  G PG       PG+ G   R  +K         
Sbjct: 1297 GE---------DGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1347

Query: 313  SPSRDALPSNVEFLLARADEASEGDSPAP--------ARPEDTPPAPPPPPAR-----DC 359
             P     P   +    +         P P        A  +D PP P  PP       D 
Sbjct: 1348 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1407

Query: 360  GASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGP 419
            G+ G      + G++      G+ G +        L  +   P   G        GP GP
Sbjct: 1408 GSKGEKGHPGLIGLIGPPGEQGEKGDRG-------LPGTQGSPGAKGDGGIPGPAGPLGP 1460

Query: 420  PEPPPADSPATAPGPDDAEGTA 441
            P PP    P    G   + G A
Sbjct: 1461 PGPPGLPGPQGPKGNKGSTGPA 1482


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 90/371 (24%), Positives = 113/371 (30%), Gaps = 88/371 (23%)

Query: 94   PGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGP 153
            PG   EK A  VA + G   +      +G  G+     K   +       PP P G  GP
Sbjct: 861  PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 920

Query: 154  ---------PAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSA 204
                     P  +  P   G+D        +     QR     Q    P  P  VV    
Sbjct: 921  QGPQGPVGFPGPKGPPGPPGKD-------GLPGHPGQRGETGFQGKTGPPGPGGVV---- 969

Query: 205  EQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFR 264
               GP    G     G                +R  P          PGP PGE  +   
Sbjct: 970  ---GPQGPTGETGPIG----------------ERGHPGP--------PGP-PGEQGLPG- 1000

Query: 265  ISNGREPRAPDSGLPSGGGGRPGCA----YPGSPG-PGARAKDKITCDLYQLISPSRDAL 319
             + G+E    D G P G  G+ G A    +PG  G PGA+    +         P     
Sbjct: 1001 -AAGKEGAKGDPG-PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGS 1058

Query: 320  PSNVEFLLARADEASEGDSPAPARPEDTPPAPPPP-----------PARDCGASGFHVDV 368
            P        R    + G    P RP   P  PP P           P    G  G    V
Sbjct: 1059 PGE------RGSAGTAGPIGLPGRP--GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1110

Query: 369  VVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSP 428
             + G        G+DG K              E   PGQ     ++G +GPP PP    P
Sbjct: 1111 GLPGPAGPAGSPGEDGDKG-------------EIGEPGQKGSKGDKGENGPPGPPGLQGP 1157

Query: 429  ATAPGPDDAEG 439
              APG    +G
Sbjct: 1158 VGAPGIAGGDG 1168



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 99/437 (22%), Positives = 134/437 (30%), Gaps = 78/437 (17%)

Query: 14   PRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLL 73
            P P G      PR    A  P+  P P G +  D  P       P    + P   P P  
Sbjct: 876  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ-GPQGPVGFPGPKG 934

Query: 74   SAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKR 133
                 G +G           PG+  ++       + G       +  +G  G      +R
Sbjct: 935  PPGPPGKDGL----------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 984

Query: 134  RRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRP 193
                      PP P G +G P A     + G+                      Q     
Sbjct: 985  GH------PGPPGPPGEQGLPGAAGKEGAKGDP-------------------GPQGISGK 1019

Query: 194  TTPAPVVFVSAEQGGPAKGVGSERRSG--GGDCSRVAEAVAHFEAQRDSPPTKG-LRKEE 250
              PA +     E+G P    G++   G  GG+  +          +R S  T G +    
Sbjct: 1020 DGPAGLRGFPGERGLP----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1075

Query: 251  RPGP-GPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYP-GSPGPGARAKDKITCDL 308
            RPGP GP             E  AP    P G  GR G   P G PGP   A        
Sbjct: 1076 RPGPQGPP--------GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG------- 1120

Query: 309  YQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDV 368
                SP  D     +        + S+GD     + E+ PP PP       GA G     
Sbjct: 1121 ----SPGEDGDKGEIG---EPGQKGSKGD-----KGENGPPGPPGLQG-PVGAPGIAGGD 1167

Query: 369  VVTGVVDECIFFGKDGTKNVK-----EETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPP 423
               G   +   FG+ G +  +        + L   P  P   G+   +   GP GPP P 
Sbjct: 1168 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1227

Query: 424  PADSPATAPGPDDAEGT 440
                P  A GP    G+
Sbjct: 1228 GPQGPNGADGPQGPPGS 1244



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 78/309 (25%), Positives = 98/309 (31%), Gaps = 84/309 (27%)

Query: 140 PTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPV 199
           PT  P DPG R GPP     P + G                            P  P  +
Sbjct: 461 PTGPPGDPGDR-GPPGRPGLPGADG---------------------------LPGPPGTM 492

Query: 200 VFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFE----AQRDSPPTKGLRKEERPGPG 255
           + +    GG           G    ++ A+A A  +    A R  P   GL     P  G
Sbjct: 493 LMLPFRYGGDGS-------KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGG 545

Query: 256 PGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPG-PGARAKDKITCDLYQLISP 314
           PG        S+G +  + D G P G  G  G   PG  G PG R +            P
Sbjct: 546 PG--------SSGAKGESGDPG-PQGPRGVQGP--PGPTGKPGKRGR------------P 582

Query: 315 SRDALPSNVEFLLARADEASEGDSPAPA----RPEDTPPAPPPPPARDCGASGFHVDVVV 370
             D          A+ D   +G    P     R E  P  PP PP  D G  G   ++  
Sbjct: 583 GADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD-GMRGEDGEIGP 641

Query: 371 TGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPAT 430
            G+  E    G  G +           +P  P  PG        G DGPP P     P  
Sbjct: 642 RGLPGEAGPRGLLGPRG----------TPGAPGQPGMA------GVDGPPGPKGNMGPQG 685

Query: 431 APGPDDAEG 439
            PGP   +G
Sbjct: 686 EPGPPGQQG 694



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 100/421 (23%), Positives = 128/421 (30%), Gaps = 103/421 (24%)

Query: 34   PSACPEPGG--GAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLLDTWYV 91
            P   P P G  GA  + GP            + P   P P   A + G++G    D   +
Sbjct: 1079 PQGPPGPAGEKGAPGEKGPQGPAGRD---GVQGPVGLPGPAGPAGSPGEDG----DKGEI 1131

Query: 92   IKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKA-------- 143
             +PG    K         G       +   G  G D     R ++ +   K         
Sbjct: 1132 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1191

Query: 144  -PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFV 202
             PP P G +G P     P   GE+ D+               +     P P  P      
Sbjct: 1192 GPPGPIGLQGLPGP---PGEKGENGDV-------------GPMGPPGPPGPRGPQGPNGA 1235

Query: 203  SAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTK---GLRKEERPGPGPGEV 259
               QG P    GS    GG     V E     EA    PP +   G  K ER   G    
Sbjct: 1236 DGPQGPP----GSVGSVGG-----VGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG---- 1282

Query: 260  RIAFRISNGREPRAPDSGLPSGGGGRPGCAYP-GSPGPGARAKDKITCDLYQLISPSRDA 318
                      E   P +  P G  G PG   P G+PGP     D           P  + 
Sbjct: 1283 ----------EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP---------GPPGEP 1323

Query: 319  LPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECI 378
             P+  + +    D+  +GD   P  P  +  A PP P    G  G        G      
Sbjct: 1324 GPAGQDGV--GGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG------AAGAE---- 1371

Query: 379  FFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAE 438
              G+ G K  K E            PPG+       GP GP        PA  PGP+   
Sbjct: 1372 --GRQGEKGAKGEAGA-------EGPPGKT------GPVGP------QGPAGKPGPEGLR 1410

Query: 439  G 439
            G
Sbjct: 1411 G 1411



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 74/322 (22%), Positives = 96/322 (29%), Gaps = 47/322 (14%)

Query: 144  PPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVS 203
            PP P G +GP  A+ GP      V        V  V ++        P P   A V    
Sbjct: 1223 PPGPRGPQGPNGAD-GPQGPPGSVG------SVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1275

Query: 204  AEQG-----GPAKGVGSERRSG--GGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGP 256
             E+G     GP    G     G  G D  +       F      P   G   ++  G   
Sbjct: 1276 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK 1335

Query: 257  GEVRIAFRISNGREPRAPDSGLPSGGGGRPGC----AYPGSPGPGARAKDKITCDLYQLI 312
            GE           +P  P    PSG  G PG       PG+ G   R  +K         
Sbjct: 1336 GE---------DGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1386

Query: 313  SPSRDALPSNVEFLLARADEASEGDSPAP--------ARPEDTPPAPPPPPAR-----DC 359
             P     P   +    +         P P        A  +D PP P  PP       D 
Sbjct: 1387 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1446

Query: 360  GASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGP 419
            G+ G      + G++      G+ G +        L  +   P   G        GP GP
Sbjct: 1447 GSKGEKGHPGLIGLIGPPGEQGEKGDRG-------LPGTQGSPGAKGDGGIPGPAGPLGP 1499

Query: 420  PEPPPADSPATAPGPDDAEGTA 441
            P PP    P    G   + G A
Sbjct: 1500 PGPPGLPGPQGPKGNKGSTGPA 1521


>gi|208022661 hypothetical protein LOC57701 [Homo sapiens]
          Length = 1334

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 86/362 (23%), Positives = 137/362 (37%), Gaps = 61/362 (16%)

Query: 28   PSAALKPSACPEPGGGAEP---DHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRV 84
            P A L     P+P  G  P   D G   +++TP       P+  P  L   +A  ++   
Sbjct: 830  PGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEK--- 886

Query: 85   LLDTWYVIKPGNTKEKVAFFVAHQCGGGSRA---SSMKVKGHWGSDSSKAKRRRRCLDPT 141
                  V+K    +E V      +   G+     ++  +   +G   SK     R  + T
Sbjct: 887  ------VMK--GIEENVLRLQGQERAPGAEVKHRNTSSIASWFGLKKSKLPALNRRTEAT 938

Query: 142  KAPPDPGGREGPPAAEEGPASAGE-DVDLLSVAEMVA--------LVEQRAALALQSYPR 192
            K     GG  G P   E    A + + + L++++++A        L E++A L+ ++ PR
Sbjct: 939  KNKEGAGG--GSPLRREVKMEARKLEAESLNISKLMAKAEDLRRALEEEKAYLSSRARPR 996

Query: 193  PTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSP--PTKGLRKEE 250
            P  PAP         GP  G+G  +    G        +     + D    P+K  R+  
Sbjct: 997  PGGPAP---------GPNTGLGQVQGQLAGMYQGADTFMQQLLNRVDGKELPSKSWRE-- 1045

Query: 251  RPGPGPGEVRIAFRISNGREPR-APDSGL--PSGGGGRPGCAYPGSPG--PGARAKDKIT 305
             P P  G+ +          P   P +GL  P  G G+P    PG P   PG R +    
Sbjct: 1046 -PKPEYGDFQPVSSDPKSPWPACGPRNGLVGPLQGCGKP----PGKPSSEPGRREEMPSE 1100

Query: 306  CDLYQLISPSR----DALPSNVEFLLARADEASEGDSPAPAR--PEDTPPA--PPP--PP 355
              L + +  S      +L   ++  +        G S  P++  P+  PP   PPP  PP
Sbjct: 1101 DSLAEPVPTSHFTACGSLTRTLDSGIGTFPPPDHGSSGTPSKNLPKTKPPRLDPPPGVPP 1160

Query: 356  AR 357
            AR
Sbjct: 1161 AR 1162



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 54/232 (23%), Positives = 80/232 (34%), Gaps = 20/232 (8%)

Query: 140 PTKAPPDPGGREGPPAAEEGPAS------AGEDVDLLSVAEMVALVEQRAALALQSYPRP 193
           P++ PP   G    P    G +S      AG+  +  S   ++  + +R  L L      
Sbjct: 276 PSRGPPQAQGTSSGPNCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARRQ-LNLGQLLED 334

Query: 194 TTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPG 253
           T      F+ A   GP  G       G G  S   +A            +KGL K    G
Sbjct: 335 TESYLQAFL-AGAAGPLNG----DHPGPGQSSSPDQAPPQLSK------SKGLPKSAWGG 383

Query: 254 PGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLIS 313
             P   R  F  ++  +   P   +  G G  P  + PG P   ++ K K+         
Sbjct: 384 GTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGE 443

Query: 314 PSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPP--PARDCGASG 363
                LPS    L       +   SP+P  P+ +P  P     P R+ G+ G
Sbjct: 444 AQGPLLPSPARGLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDG 495


>gi|156416026 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 91/375 (24%), Positives = 126/375 (33%), Gaps = 75/375 (20%)

Query: 27  PPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLL 86
           PP    +P   PEP    +P+  P       P  A   P   PAP          G+   
Sbjct: 227 PPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVC--GQSFT 284

Query: 87  DTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPD 146
            +W+ +K    K K +F  A    G        +K H    +SK       L P +AP  
Sbjct: 285 QSWF-LKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK-------LGPLRAP-- 334

Query: 147 PGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPT----TPAPVVFV 202
                GP +   GPA A +  DL     ++A      AL L   P P      P+ + ++
Sbjct: 335 -----GPAS---GPARAPQPPDL----GLLAYEPLGPALLLAPAPTPAERREPPSLLGYL 382

Query: 203 SAEQG-GPAKGVGSE---RRSGGGD---CSRVAEAVAHFEAQRDSPPTKGLRKEE----- 250
           S   G G   G G+E    RS GG     S +        A+      + +  EE     
Sbjct: 383 SLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWAR 442

Query: 251 ------------RPGPGPGEVRIAFRISNGREPRAPDSGL------PSGGGGRPG--CAY 290
                       RPG GPG    A            ++GL      P GG G  G  C +
Sbjct: 443 GRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPF 502

Query: 291 PGSPGPGARAKDKITCDLYQLISPSR-------DALPSNVEFLLARAD-EASEGDSPAPA 342
            G     A    K+   ++    P +            ++++ L R   E   G  P P 
Sbjct: 503 CGKSFRSAHHL-KVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGP- 560

Query: 343 RPEDTPPAPPPPPAR 357
                PP PPPP  R
Sbjct: 561 -----PPEPPPPSQR 570



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 46/194 (23%), Positives = 69/194 (35%), Gaps = 25/194 (12%)

Query: 182 RAALALQSYPRPTTPAPVVFVSAEQGGPAKG--VGSERRSGGGDCSRVAEAVAHFEAQRD 239
           R+ L      RP +PA  + +  E+    +   +G  R SGG   +   E +A  +A   
Sbjct: 101 RSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSS 160

Query: 240 S----PPTKGLRKEERPGPG-------PGEVRIAFRISNGREPRAPDSGLPSGGGGRPGC 288
           S    P  KG  +              P +  +    S+  E     S    G   RP  
Sbjct: 161 SAFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLA 220

Query: 289 AYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTP 348
           A   +P P  + +     +   +  P  +  P           E     +PAPA PE+ P
Sbjct: 221 ATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEP-----------EREATPTPAPAAPEE-P 268

Query: 349 PAPPPPPARDCGAS 362
           PAPP    + CG S
Sbjct: 269 PAPPEFRCQVCGQS 282


>gi|156415998 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 91/375 (24%), Positives = 126/375 (33%), Gaps = 75/375 (20%)

Query: 27  PPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLL 86
           PP    +P   PEP    +P+  P       P  A   P   PAP          G+   
Sbjct: 227 PPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVC--GQSFT 284

Query: 87  DTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPD 146
            +W+ +K    K K +F  A    G        +K H    +SK       L P +AP  
Sbjct: 285 QSWF-LKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK-------LGPLRAP-- 334

Query: 147 PGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPT----TPAPVVFV 202
                GP +   GPA A +  DL     ++A      AL L   P P      P+ + ++
Sbjct: 335 -----GPAS---GPARAPQPPDL----GLLAYEPLGPALLLAPAPTPAERREPPSLLGYL 382

Query: 203 SAEQG-GPAKGVGSE---RRSGGGD---CSRVAEAVAHFEAQRDSPPTKGLRKEE----- 250
           S   G G   G G+E    RS GG     S +        A+      + +  EE     
Sbjct: 383 SLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWAR 442

Query: 251 ------------RPGPGPGEVRIAFRISNGREPRAPDSGL------PSGGGGRPG--CAY 290
                       RPG GPG    A            ++GL      P GG G  G  C +
Sbjct: 443 GRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPF 502

Query: 291 PGSPGPGARAKDKITCDLYQLISPSR-------DALPSNVEFLLARAD-EASEGDSPAPA 342
            G     A    K+   ++    P +            ++++ L R   E   G  P P 
Sbjct: 503 CGKSFRSAHHL-KVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGP- 560

Query: 343 RPEDTPPAPPPPPAR 357
                PP PPPP  R
Sbjct: 561 -----PPEPPPPSQR 570



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 46/194 (23%), Positives = 69/194 (35%), Gaps = 25/194 (12%)

Query: 182 RAALALQSYPRPTTPAPVVFVSAEQGGPAKG--VGSERRSGGGDCSRVAEAVAHFEAQRD 239
           R+ L      RP +PA  + +  E+    +   +G  R SGG   +   E +A  +A   
Sbjct: 101 RSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSS 160

Query: 240 S----PPTKGLRKEERPGPG-------PGEVRIAFRISNGREPRAPDSGLPSGGGGRPGC 288
           S    P  KG  +              P +  +    S+  E     S    G   RP  
Sbjct: 161 SAFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLA 220

Query: 289 AYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTP 348
           A   +P P  + +     +   +  P  +  P           E     +PAPA PE+ P
Sbjct: 221 ATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEP-----------EREATPTPAPAAPEE-P 268

Query: 349 PAPPPPPARDCGAS 362
           PAPP    + CG S
Sbjct: 269 PAPPEFRCQVCGQS 282


>gi|156415996 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 91/375 (24%), Positives = 126/375 (33%), Gaps = 75/375 (20%)

Query: 27  PPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLL 86
           PP    +P   PEP    +P+  P       P  A   P   PAP          G+   
Sbjct: 227 PPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVC--GQSFT 284

Query: 87  DTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPD 146
            +W+ +K    K K +F  A    G        +K H    +SK       L P +AP  
Sbjct: 285 QSWF-LKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK-------LGPLRAP-- 334

Query: 147 PGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPT----TPAPVVFV 202
                GP +   GPA A +  DL     ++A      AL L   P P      P+ + ++
Sbjct: 335 -----GPAS---GPARAPQPPDL----GLLAYEPLGPALLLAPAPTPAERREPPSLLGYL 382

Query: 203 SAEQG-GPAKGVGSE---RRSGGGD---CSRVAEAVAHFEAQRDSPPTKGLRKEE----- 250
           S   G G   G G+E    RS GG     S +        A+      + +  EE     
Sbjct: 383 SLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWAR 442

Query: 251 ------------RPGPGPGEVRIAFRISNGREPRAPDSGL------PSGGGGRPG--CAY 290
                       RPG GPG    A            ++GL      P GG G  G  C +
Sbjct: 443 GRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPF 502

Query: 291 PGSPGPGARAKDKITCDLYQLISPSR-------DALPSNVEFLLARAD-EASEGDSPAPA 342
            G     A    K+   ++    P +            ++++ L R   E   G  P P 
Sbjct: 503 CGKSFRSAHHL-KVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGP- 560

Query: 343 RPEDTPPAPPPPPAR 357
                PP PPPP  R
Sbjct: 561 -----PPEPPPPSQR 570



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 46/194 (23%), Positives = 69/194 (35%), Gaps = 25/194 (12%)

Query: 182 RAALALQSYPRPTTPAPVVFVSAEQGGPAKG--VGSERRSGGGDCSRVAEAVAHFEAQRD 239
           R+ L      RP +PA  + +  E+    +   +G  R SGG   +   E +A  +A   
Sbjct: 101 RSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSS 160

Query: 240 S----PPTKGLRKEERPGPG-------PGEVRIAFRISNGREPRAPDSGLPSGGGGRPGC 288
           S    P  KG  +              P +  +    S+  E     S    G   RP  
Sbjct: 161 SAFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLA 220

Query: 289 AYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTP 348
           A   +P P  + +     +   +  P  +  P           E     +PAPA PE+ P
Sbjct: 221 ATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEP-----------EREATPTPAPAAPEE-P 268

Query: 349 PAPPPPPARDCGAS 362
           PAPP    + CG S
Sbjct: 269 PAPPEFRCQVCGQS 282


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
            sapiens]
          Length = 2715

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 88/347 (25%), Positives = 114/347 (32%), Gaps = 69/347 (19%)

Query: 124  WGSDSSKAKRRRRCLDPTK------------APPDPGGREGPPAAEEGPASAGEDVDLLS 171
            W S   K   + R   PT             APP P     PP  + GP    ED++++S
Sbjct: 1928 WASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSP-PPPEDLGPDF--EDMEVVS 1984

Query: 172  VAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAV 231
                  L    + L  + +      A  +   +  GGP  G  SE  S            
Sbjct: 1985 GLSAADLDFAASLLGTEPFQEEIVAAGAM--GSSHGGP--GDSSEEESSP------TSRY 2034

Query: 232  AHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFR--ISNGREPRAPDSGLPSGGGGRPGCA 289
             HF     S P  GL     P   PG  RI     + +G +  A     P G G  P   
Sbjct: 2035 IHFPVTVVSAP--GLA----PSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPS-- 2086

Query: 290  YPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPP 349
                 GPG   +  +         P  D     V+F+L        GD  A  R E  PP
Sbjct: 2087 -----GPGV-VRAGVLGAAGDRARPPEDLPSEIVDFVLKNL--GGPGDGGAGPREESLPP 2138

Query: 350  APP----PPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPP 405
            APP      P++  G +    D   T       F    G   V+   + L  +PE P P 
Sbjct: 2139 APPLANGSQPSQ--GLTASPADPTRT-------FAWLPGAPGVR--VLSLGPAPEPPKPA 2187

Query: 406  GQLFFLQNR--------GPDGPPEPPPADSPATAPGPDDAEGTADTS 444
                 L N+          +G P PPP   P   P P     TA TS
Sbjct: 2188 TSKIILVNKLGQVFVKMAGEGEPVPPPVKQP---PLPPTISPTAPTS 2231



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 75/317 (23%), Positives = 102/317 (32%), Gaps = 59/317 (18%)

Query: 140 PTKAPPDPGGRE----GPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTT 195
           P  +PP P  +E     PP       S       L+ ++     E+ AA A      P T
Sbjct: 440 PLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA---EREAARAGPEGTSPPT 496

Query: 196 PAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRK---EERP 252
           P P    S   GGP +   +           + + +    + R S   K  R+   E+ P
Sbjct: 497 PTP----STATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPP 552

Query: 253 GPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCD-LYQL 311
            P   EV    R      P  P    P     R     P +P P    +  I  +  ++ 
Sbjct: 553 KPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTP-PSTPVPLPEKRRSILREPTFRW 611

Query: 312 ISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVT 371
            S +R+  P                  P PA P    P+PPP PA              T
Sbjct: 612 TSLTRELPP------------------PPPAPPPPPAPSPPPAPA--------------T 639

Query: 372 GVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGP-PEPPPADSPAT 430
                 +      T +  E  + +  S   PPP G         P+ P PEPPPAD    
Sbjct: 640 SSRRPLLLRAPQFTPS--EAHLKIYESVLTPPPLG--------APEAPEPEPPPADDSPA 689

Query: 431 APGPDDAEGTADTSLCR 447
            P P     T   SL R
Sbjct: 690 EPEPRAVGRTNHLSLPR 706



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 59/251 (23%), Positives = 89/251 (35%), Gaps = 49/251 (19%)

Query: 126 SDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAAL 185
           + + +A R R C   T  P    GR  PP    GP    +           A+V   AA+
Sbjct: 200 AQAPQAPRSRACEPST--PRRSRGR--PPGRPAGPCRRKQQ----------AVVVAEAAV 245

Query: 186 ALQSYPRPTTPAPVVFVSAEQG------GPAKGVGSERRSG--------------GGDCS 225
            +   P+P  P PVV V  + G      GP  G G+ RR G              GG   
Sbjct: 246 TI---PKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLP 302

Query: 226 RVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGR 285
            V + V+  +  +    + GL      G G G+   +++         P   + SG GG 
Sbjct: 303 FVIKFVSRAKKVKMGQLSLGLES----GQGQGQHEESWQ-------DVPQRRVGSGQGGS 351

Query: 286 PGCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPE 345
           P C            ++K   +        ++      E + A   E ++   P    P 
Sbjct: 352 P-CWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPA 410

Query: 346 DTPPAPPPPPA 356
            +PP P PPP+
Sbjct: 411 PSPPPPLPPPS 421



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 4/57 (7%)

Query: 27  PPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGR 83
           PPS +  P  CP P     P   P    + PP  A E     P P++ A  +   GR
Sbjct: 419 PPSTSPPPPLCPPP----PPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGR 471



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 44/175 (25%), Positives = 57/175 (32%), Gaps = 39/175 (22%)

Query: 207 GGPAKGVGSER------RSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVR 260
           G   +G G+ER      R GG      AE        R     +GLR+  R   GP    
Sbjct: 32  GRGGRGNGAERVRVALRRGGGATGPGGAEPGEDTALLRLLGLRRGLRRLRRLWAGP---- 87

Query: 261 IAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDALP 320
              R+  GR       G   G G   GC        G   +++     +Q      D  P
Sbjct: 88  ---RVQRGR-----GRGRGRGWGPSRGCVPEEESSDGESDEEE-----FQGFHSDEDVAP 134

Query: 321 SNVEFLLARADEASEGDSPA------------PARPEDTPPAPPPPPARDCGASG 363
           S++   L     +  G +P             P R  D  P PP  PAR  G  G
Sbjct: 135 SSLRSAL----RSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEG 185


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 57/234 (24%), Positives = 71/234 (30%), Gaps = 49/234 (20%)

Query: 212 GVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERP-GPGPGEVRIAFRISNGRE 270
           G G  RR GGG    + +        R  PP  GL +   P GPGPG+       S  + 
Sbjct: 13  GGGFHRRGGGGGRGGLHDF-------RSPPPGMGLNQNRGPMGPGPGQ-------SGPKP 58

Query: 271 PRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARA 330
           P  P           P    P  P P             Q   P +D+       ++A+ 
Sbjct: 59  PIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKP----VVAQG 114

Query: 331 DEASEGDSPAPARPEDTPPAPPP----PPARDCGASGFHVDVVVTGVVDECIFFGKDGTK 386
              + G   AP      PPA PP    PP    G +      V                 
Sbjct: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVT---------------- 158

Query: 387 NVKEETVCLTVSPEEPPPPGQLFFLQNRGPD-GPPEPPPADSPATAPGPDDAEG 439
                    +  P  PPP      +    P  G P PPPA  P   PGP    G
Sbjct: 159 ---------SAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPG 203



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 38/118 (32%), Positives = 43/118 (36%), Gaps = 20/118 (16%)

Query: 188 QSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLR 247
           Q  P P        V A+  GPA GVGS                A   A   +PPT G  
Sbjct: 96  QQQPPPPPQDSSKPVVAQGPGPAPGVGSA-------------PPASSSAPPATPPTSGAP 142

Query: 248 KEERPGPGPGEVRIAFRISNGR-EPRAPDSGLP-----SGGGGRPGCAYPGSPGPGAR 299
               PGP P           G   P  P SG+P     +GG   P  A PG PGPG +
Sbjct: 143 PGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPG-PGPGPK 199



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 20/78 (25%), Positives = 25/78 (32%), Gaps = 22/78 (28%)

Query: 14  PRPFGTYSQNQPRPPSAALKPSACPEPG----------------------GGAEPDHGPA 51
           P P     Q  P PP  + KP     PG                       GA P  GP 
Sbjct: 89  PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPG 148

Query: 52  HSENTPPALATEVPASQP 69
            +   PPA+ +  P + P
Sbjct: 149 PTPTPPPAVTSAPPGAPP 166


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 32/106 (30%), Positives = 39/106 (36%), Gaps = 7/106 (6%)

Query: 339 PAPARPEDTPPAPPPPPARDCGASGFHVDV---VVTGVVDECIFFGKDGTKNVKEETVCL 395
           P P + +      PPPPA     SG  +     V  G        G  G + +      L
Sbjct: 8   PPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAAL 67

Query: 396 TVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGTA 441
            + P  PPPP          P  PP PPPA + A A GP    G A
Sbjct: 68  LLHPPPPPPPATAA----PPPPPPPPPPPASAAAPASGPPAPPGLA 109


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 73/288 (25%), Positives = 92/288 (31%), Gaps = 59/288 (20%)

Query: 140 PTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALA--LQSYPRPTTPA 197
           P   PP P G   PP     P S   D   L  A+     + R+AL   +Q   R     
Sbjct: 10  PLPPPPPPLGAPPPPPPSAPPVST--DTSSLRRADP----KGRSALLADIQQGTRLRKVT 63

Query: 198 PVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPG 257
            +   SA Q   +KG   E   GGG  +    +         +PPT G            
Sbjct: 64  QINDRSAPQIESSKGTNKE---GGGSANTRGAS---------TPPTLG------------ 99

Query: 258 EVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRD 317
                  +  G  P    +G     GG+ G   PGS  P  R  +K       LI P+  
Sbjct: 100 ------DLFAGGFPVLRPAGQRDVAGGKTGQG-PGSRAPSPRLPNKTISG--PLIPPASP 150

Query: 318 ALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDEC 377
            L +  E   A        + PAP  P   PP PP PP     +       + T +V   
Sbjct: 151 RLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSP------IKTPLVSPP 204

Query: 378 IFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPA 425
               K     V     C    P  PPPP             PP  PPA
Sbjct: 205 GPLTKGNLPVVAPPVPCAPPPPPPPPPP------------TPPPLPPA 240



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 34/124 (27%), Positives = 43/124 (34%), Gaps = 15/124 (12%)

Query: 335 EGDSPAPARPEDTPPAPPPP--PARDCGASGFHVDVVVTGVVDECI----FFGKDGTKNV 388
           + +  +PA+    PPAPPPP  P   C          + GV            K  +   
Sbjct: 276 KAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQA 335

Query: 389 KEETVCLTVSPEEPPPPGQLFFLQNR---------GPDGPPEPPPADSPATAPGPDDAEG 439
             +       P  P PPG   FLQ +         G   PP  PPA SP T       + 
Sbjct: 336 PPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQA 395

Query: 440 TADT 443
           TA T
Sbjct: 396 TAWT 399



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 9/99 (9%)

Query: 267 NGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFL 326
           + +EP AP   LP      P  + P  P PG  +  +    L    SPS  A P      
Sbjct: 285 DAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPK-SPSFQAPPQKAGAQ 343

Query: 327 LARADEASEGDSPAPARPEDTPPA--------PPPPPAR 357
              A  A  G  P   +     P         PP PPAR
Sbjct: 344 ALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPAR 382


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.137    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,815,332
Number of Sequences: 37866
Number of extensions: 2418006
Number of successful extensions: 31053
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 820
Number of HSP's that attempted gapping in prelim test: 19969
Number of HSP's gapped (non-prelim): 9061
length of query: 603
length of database: 18,247,518
effective HSP length: 108
effective length of query: 495
effective length of database: 14,157,990
effective search space: 7008205050
effective search space used: 7008205050
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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