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Search of human proteins with 122937189
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937189 family with sequence similarity 155, member A
[Homo sapiens]
(458 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937189 family with sequence similarity 155, member A [Homo... 956 0.0
gi|56676337 transmembrane protein 28 [Homo sapiens] 254 1e-67
gi|4507379 TATA box binding protein [Homo sapiens] 60 5e-09
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa... 59 1e-08
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 58 2e-08
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 58 2e-08
gi|40354197 THAP domain containing 11 [Homo sapiens] 58 2e-08
gi|33286444 mastermind-like 2 [Homo sapiens] 56 6e-08
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 56 8e-08
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 56 8e-08
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 56 8e-08
gi|189491748 ataxin 1 [Homo sapiens] 55 1e-07
gi|51479158 ataxin 1 [Homo sapiens] 55 1e-07
gi|90903231 huntingtin [Homo sapiens] 55 2e-07
gi|55956910 meningioma 1 [Homo sapiens] 55 2e-07
gi|171543895 ataxin 2 [Homo sapiens] 54 2e-07
gi|56549696 E1A binding protein p400 [Homo sapiens] 54 3e-07
gi|110347429 mediator complex subunit 12 [Homo sapiens] 53 5e-07
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 52 1e-06
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 52 1e-06
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens] 52 1e-06
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 51 2e-06
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 51 2e-06
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s... 51 2e-06
gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 51 2e-06
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 51 2e-06
gi|38158015 mastermind-like 3 [Homo sapiens] 49 9e-06
gi|226442791 runt-related transcription factor 2 isoform b [Homo... 48 2e-05
gi|226442783 runt-related transcription factor 2 isoform a [Homo... 48 2e-05
gi|66934969 runt-related transcription factor 2 isoform c [Homo ... 48 2e-05
>gi|122937189 family with sequence similarity 155, member A [Homo
sapiens]
Length = 458
Score = 956 bits (2470), Expect = 0.0
Identities = 458/458 (100%), Positives = 458/458 (100%)
Query: 1 MTRGAWMCRQYDDGLKIWLAAPRENEKPFIDSERAQKWRLSLASLLFFTVLLSDHLWFCA 60
MTRGAWMCRQYDDGLKIWLAAPRENEKPFIDSERAQKWRLSLASLLFFTVLLSDHLWFCA
Sbjct: 1 MTRGAWMCRQYDDGLKIWLAAPRENEKPFIDSERAQKWRLSLASLLFFTVLLSDHLWFCA 60
Query: 61 EAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAH 120
EAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAH
Sbjct: 61 EAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAH 120
Query: 121 RLLSASSSPTLPPSPGDGGGGGGKGNRGKDDRGKALFLGNSAKPVWRLETCYPQGASSGQ 180
RLLSASSSPTLPPSPGDGGGGGGKGNRGKDDRGKALFLGNSAKPVWRLETCYPQGASSGQ
Sbjct: 121 RLLSASSSPTLPPSPGDGGGGGGKGNRGKDDRGKALFLGNSAKPVWRLETCYPQGASSGQ 180
Query: 181 CFTVENADAVCARNWSRGAAGGDGQEVRSKHPTPLWNLSDFYLSFCNSYTLWELFSGLSS 240
CFTVENADAVCARNWSRGAAGGDGQEVRSKHPTPLWNLSDFYLSFCNSYTLWELFSGLSS
Sbjct: 181 CFTVENADAVCARNWSRGAAGGDGQEVRSKHPTPLWNLSDFYLSFCNSYTLWELFSGLSS 240
Query: 241 PNTLNCSLDVVLKEGGEMTTCRQCVEAYQDYDHHAQEKYEEFESVLHKYLQSEEYSVKSC 300
PNTLNCSLDVVLKEGGEMTTCRQCVEAYQDYDHHAQEKYEEFESVLHKYLQSEEYSVKSC
Sbjct: 241 PNTLNCSLDVVLKEGGEMTTCRQCVEAYQDYDHHAQEKYEEFESVLHKYLQSEEYSVKSC 300
Query: 301 PEDCKIVYKAWLCSQYFEVTQFNCRKTIPCKQYCLEVQTRCPFILPDNDEVIYGGLSSFI 360
PEDCKIVYKAWLCSQYFEVTQFNCRKTIPCKQYCLEVQTRCPFILPDNDEVIYGGLSSFI
Sbjct: 301 PEDCKIVYKAWLCSQYFEVTQFNCRKTIPCKQYCLEVQTRCPFILPDNDEVIYGGLSSFI 360
Query: 361 CTGLYETFLTNDEPECCDVRREEKSNNPSKGTVEKSGSCHRTSLTVSSATRLCNSRLKLC 420
CTGLYETFLTNDEPECCDVRREEKSNNPSKGTVEKSGSCHRTSLTVSSATRLCNSRLKLC
Sbjct: 361 CTGLYETFLTNDEPECCDVRREEKSNNPSKGTVEKSGSCHRTSLTVSSATRLCNSRLKLC 420
Query: 421 VLVLILLHTVLTASAAQNTAGLSFGGINTLEENSTNEE 458
VLVLILLHTVLTASAAQNTAGLSFGGINTLEENSTNEE
Sbjct: 421 VLVLILLHTVLTASAAQNTAGLSFGGINTLEENSTNEE 458
>gi|56676337 transmembrane protein 28 [Homo sapiens]
Length = 472
Score = 254 bits (648), Expect = 1e-67
Identities = 128/280 (45%), Positives = 168/280 (60%), Gaps = 41/280 (14%)
Query: 220 DFYLSFCNSYTLWELFSGLSSPNTLNCSLDVVLKE---------GGEMTTCRQCVEAYQD 270
+F LSFC++YT+W+L G+ P++L+CSLD ++ + G C C+EAYQ
Sbjct: 193 NFTLSFCDTYTVWDLLLGMDRPDSLDCSLDTLMGDLLAVVASPGSGAWEACSNCIEAYQR 252
Query: 271 YDHHAQEKYEEFESVLHKYLQSEEYSVKSCPEDCKIVYKAWLCSQYFEVTQFNCRKTIPC 330
D HAQEKY+EF+ VLHKYLQ+EEYS++SC + CK VYKAWLCS+YF VTQ C++ +PC
Sbjct: 253 LDRHAQEKYDEFDLVLHKYLQAEEYSIRSCTKGCKAVYKAWLCSEYFSVTQQECQRWVPC 312
Query: 331 KQYCLEVQTRCPFILPDNDEVIYGGLSSFICTGLYETFLTNDEPECCDVRREEKSNNPSK 390
KQYCLEVQTRCPFILPDN+E++YGGL FICTGL +T E +CCDV+ K
Sbjct: 313 KQYCLEVQTRCPFILPDNEEMVYGGLPGFICTGLLDTSPKRLETKCCDVQWVSCEAKKKK 372
Query: 391 GTVEKSGSCHRTS--------------------------------LTVSSATRLCNSRLK 418
++ H+ L VS +RL SR++
Sbjct: 373 FKESEAPKTHQQQFHHSYFHHYHQQYHHYHPHHDPPGRVSNKPALLPVSGGSRLSPSRIR 432
Query: 419 LCVLVLILLHTVLTASAAQNTAGLSFGGINTLEENSTNEE 458
LCVLVL+LLHTV++ S+ Q GL + LEE T EE
Sbjct: 433 LCVLVLMLLHTVVSFSSNQGGGGLGLETLPALEEGLTREE 472
Score = 77.0 bits (188), Expect = 3e-14
Identities = 45/74 (60%), Positives = 51/74 (68%), Gaps = 6/74 (8%)
Query: 1 MTRGAWMCRQYDDG-LKIWLA----APRENEKPFIDSERAQKWRLSLASLLFFTVLLSDH 55
M RGAWM D L I APR ++KP DSERAQ+WRLSLASLLFFTVLL+DH
Sbjct: 1 MFRGAWMWPGKDAAALTICCCCCCWAPRPSDKPCADSERAQRWRLSLASLLFFTVLLADH 60
Query: 56 LWFCAEAKLTRARD 69
LW CA A+ RAR+
Sbjct: 61 LWLCAGAR-PRARE 73
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 59.7 bits (143), Expect = 5e-09
Identities = 34/78 (43%), Positives = 49/78 (62%), Gaps = 7/78 (8%)
Query: 66 RARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSA 125
R + ++ QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+ A+ A+ + S + QA + S
Sbjct: 57 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSG 116
Query: 126 -------SSSPTLPPSPG 136
S + T P PG
Sbjct: 117 QAPQLFHSQTLTTAPLPG 134
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/70 (38%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 68 RDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASS 127
+ ++ QQQQ+QQQQQQQQQ+Q+Q QQ S A + G++ + L +A
Sbjct: 73 QQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPL 132
Query: 128 SPTLP--PSP 135
T P PSP
Sbjct: 133 PGTTPLYPSP 142
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/64 (34%), Positives = 33/64 (51%)
Query: 76 QRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTLPPSP 135
+ QQ+QQQQQQ+Q+QQQQQQ++QQ+ + QA + S + +
Sbjct: 53 EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112
Query: 136 GDGG 139
G G
Sbjct: 113 GTSG 116
>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
sapiens]
Length = 443
Score = 58.5 bits (140), Expect = 1e-08
Identities = 34/67 (50%), Positives = 43/67 (64%), Gaps = 4/67 (5%)
Query: 75 QQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTLPPS 134
QQ+ QQQQQQQQ+Q+QQQQQQ++QQ P P L+ P A R SA+++ LPPS
Sbjct: 125 QQQHQQQQQQQQQQQQQQQQQQQQQRP--PHLVHHAANHHPGPGAWR--SAAAAAHLPPS 180
Query: 135 PGDGGGG 141
G GG
Sbjct: 181 MGASNGG 187
Score = 30.0 bits (66), Expect = 4.6
Identities = 16/43 (37%), Positives = 20/43 (46%)
Query: 108 ASMGESSPAAQAHRLLSASSSPTLPPSPGDGGGGGGKGNRGKD 150
A P + AH+ ++A S G GGGGGG G G D
Sbjct: 47 ALQSNGHPLSHAHQWITALSHGGGGGGGGGGGGGGGGGGGGGD 89
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 57.8 bits (138), Expect = 2e-08
Identities = 36/74 (48%), Positives = 43/74 (58%), Gaps = 11/74 (14%)
Query: 73 QQQQRQQQQQQQQQRQRQQQQQQRRQQEP-------SWPALLASMGESSPAAQAHRLLSA 125
QQQQ+QQQQQQQQQ+Q+QQQQQQ +QQ P PAL+ S P + LS
Sbjct: 216 QQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPE----LSG 271
Query: 126 SSSPTLPPSPGDGG 139
S+P P P GG
Sbjct: 272 PSTPQKLPVPAPGG 285
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 57.8 bits (138), Expect = 2e-08
Identities = 36/74 (48%), Positives = 43/74 (58%), Gaps = 11/74 (14%)
Query: 73 QQQQRQQQQQQQQQRQRQQQQQQRRQQEP-------SWPALLASMGESSPAAQAHRLLSA 125
QQQQ+QQQQQQQQQ+Q+QQQQQQ +QQ P PAL+ S P + LS
Sbjct: 216 QQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPE----LSG 271
Query: 126 SSSPTLPPSPGDGG 139
S+P P P GG
Sbjct: 272 PSTPQKLPVPAPGG 285
>gi|40354197 THAP domain containing 11 [Homo sapiens]
Length = 314
Score = 57.8 bits (138), Expect = 2e-08
Identities = 32/77 (41%), Positives = 47/77 (61%)
Query: 60 AEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQA 119
A A R R ++ QQQQ+QQQQQQQQQ+Q+QQQQQQ++ + A A + + +A A
Sbjct: 95 AGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQPNLVSASA 154
Query: 120 HRLLSASSSPTLPPSPG 136
LL+ ++ +PG
Sbjct: 155 AVLLTLQATVDSSQAPG 171
Score = 48.1 bits (113), Expect = 2e-05
Identities = 29/72 (40%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 61 EAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAH 120
E K+ R ++RQQQQQQQQQ+Q+QQQQQQ++QQ+ + ++ AQ
Sbjct: 87 ERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQ 146
Query: 121 -RLLSASSSPTL 131
L+SAS++ L
Sbjct: 147 PNLVSASAAVLL 158
Score = 48.1 bits (113), Expect = 2e-05
Identities = 30/75 (40%), Positives = 41/75 (54%)
Query: 60 AEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQA 119
A A+ + + ++ QQQQ+QQQQQQQQQ+Q+QQQQQ + A L S+ AA
Sbjct: 98 AAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQPNLVSASAAVL 157
Query: 120 HRLLSASSSPTLPPS 134
L + S P S
Sbjct: 158 LTLQATVDSSQAPGS 172
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 56.2 bits (134), Expect = 6e-08
Identities = 28/51 (54%), Positives = 39/51 (76%)
Query: 68 RDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQ 118
+ ++ QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+ S A +SS +AQ
Sbjct: 589 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQ 639
Score = 53.1 bits (126), Expect = 5e-07
Identities = 25/33 (75%), Positives = 30/33 (90%)
Query: 73 QQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPA 105
QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ S PA
Sbjct: 639 QQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPA 671
Score = 48.9 bits (115), Expect = 9e-06
Identities = 23/39 (58%), Positives = 30/39 (76%)
Query: 67 ARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPA 105
A+ ++ QQQQ+QQQQQQQQQ+Q+QQQQQ Q S P+
Sbjct: 638 AQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPS 676
Score = 48.1 bits (113), Expect = 2e-05
Identities = 21/29 (72%), Positives = 27/29 (93%)
Query: 72 HQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
H QQ+QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 585 HYTQQQQQQQQQQQQQQQQQQQQQQQQQQ 613
Score = 48.1 bits (113), Expect = 2e-05
Identities = 21/29 (72%), Positives = 28/29 (96%)
Query: 72 HQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
+ QQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 586 YTQQQQQQQQQQQQQQQQQQQQQQQQQQQ 614
Score = 47.4 bits (111), Expect = 3e-05
Identities = 24/48 (50%), Positives = 34/48 (70%), Gaps = 2/48 (4%)
Query: 61 EAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQ--QQRRQQEPSWPAL 106
++ ++ + ++ QQQQ+QQQQQQQQQ+Q+QQQQ Q Q PS P L
Sbjct: 633 QSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLL 680
Score = 47.0 bits (110), Expect = 4e-05
Identities = 24/52 (46%), Positives = 37/52 (71%), Gaps = 5/52 (9%)
Query: 56 LWFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQ-----QQRRQQEPS 102
L + + + + + ++ QQQQ+QQQQQQQQQ+Q+QQQQ QQ++QQ+ S
Sbjct: 584 LHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSS 635
Score = 43.9 bits (102), Expect = 3e-04
Identities = 24/49 (48%), Positives = 33/49 (67%), Gaps = 5/49 (10%)
Query: 73 QQQQRQ-----QQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPA 116
QQQQ+Q QQQQQQQQ+Q+QQQQQQ++QQ+ + +S P+
Sbjct: 628 QQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPS 676
Score = 43.5 bits (101), Expect = 4e-04
Identities = 22/33 (66%), Positives = 28/33 (84%), Gaps = 5/33 (15%)
Query: 73 QQQQRQQ-----QQQQQQQRQRQQQQQQRRQQE 100
QQQQ+QQ QQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 627 QQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQ 659
Score = 42.7 bits (99), Expect = 7e-04
Identities = 23/50 (46%), Positives = 32/50 (64%)
Query: 79 QQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSS 128
QQQQQQQQ+Q+QQQQQQ++QQ+ +SS +AQ + +S S
Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSIS 637
Score = 42.7 bits (99), Expect = 7e-04
Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 22/57 (38%)
Query: 68 RDKEHQ----------------------QQQRQQQQQQQQQRQRQQQQQQRRQQEPS 102
+ ++ Q QQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+PS
Sbjct: 611 QQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPS 667
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/51 (45%), Positives = 31/51 (60%)
Query: 78 QQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSS 128
QQQQQQQQQ+Q+QQQQQQ++QQ+ S A Q + S+ S+
Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISA 638
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/69 (37%), Positives = 36/69 (52%), Gaps = 17/69 (24%)
Query: 68 RDKEHQQQQRQQQQQQQ-----------------QQRQRQQQQQQRRQQEPSWPALLASM 110
+ ++ QQQQ+QQQQQQQ QQ+Q+QQQQQQ++QQ+
Sbjct: 605 QQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQ 664
Query: 111 GESSPAAQA 119
SS AQ+
Sbjct: 665 QPSSQPAQS 673
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 7/88 (7%)
Query: 60 AEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQA 119
A L ++ H QQ +Q +QQ + QQ QQQ Q +W AL +S G S
Sbjct: 420 ASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQ--HQPTNWSALPSSAGPSPGPFGQ 477
Query: 120 HRLLSAS-----SSPTLPPSPGDGGGGG 142
++ S S SP P PG GG G
Sbjct: 478 EKIPSPSFGQQTFSPQSSPMPGVAGGSG 505
Score = 37.7 bits (86), Expect = 0.022
Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 18/94 (19%)
Query: 60 AEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE------PSWPALLASMGES 113
A+ + + + ++ QQQQ+QQQQQQQQQ+ Q Q Q P LL ++
Sbjct: 638 AQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQN 697
Query: 114 SPAA------------QAHRLLSASSSPTLPPSP 135
P A H ++ ++ P+ P+P
Sbjct: 698 QPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNP 731
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 55.8 bits (133), Expect = 8e-08
Identities = 25/47 (53%), Positives = 36/47 (76%)
Query: 55 HLWFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEP 101
HL + + + + ++ QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ P
Sbjct: 147 HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP 193
Score = 53.1 bits (126), Expect = 5e-07
Identities = 28/58 (48%), Positives = 39/58 (67%), Gaps = 2/58 (3%)
Query: 68 RDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSA 125
+ ++ QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+ P A E Q + L+A
Sbjct: 157 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAK--EQQQQQQQQQQLAA 212
Score = 49.3 bits (116), Expect = 7e-06
Identities = 24/46 (52%), Positives = 31/46 (67%)
Query: 74 QQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQA 119
QQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+ + P QA
Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 197
Score = 45.4 bits (106), Expect = 1e-04
Identities = 20/35 (57%), Positives = 30/35 (85%)
Query: 66 RARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
+ +++ H Q +QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 141 KQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175
Score = 40.0 bits (92), Expect = 0.004
Identities = 20/33 (60%), Positives = 27/33 (81%), Gaps = 2/33 (6%)
Query: 70 KEHQQQQRQQ--QQQQQQQRQRQQQQQQRRQQE 100
K+ Q+Q Q QQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 140 KKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 172
Score = 39.3 bits (90), Expect = 0.008
Identities = 29/77 (37%), Positives = 37/77 (48%), Gaps = 12/77 (15%)
Query: 68 RDKEHQQQQRQQQQQQQ--------QQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQA 119
+ ++ QQQQ+QQQQQQQ QQ+Q+QQQQQ QQ LL + Q
Sbjct: 175 QQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL----QMQQLQQQ 230
Query: 120 HRLLSASSSPTLPPSPG 136
LLS + PG
Sbjct: 231 QHLLSLQRQGLISIPPG 247
Score = 34.3 bits (77), Expect = 0.24
Identities = 15/29 (51%), Positives = 23/29 (79%)
Query: 72 HQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
+++QQ Q Q QQ+Q+QQQQQQ++QQ+
Sbjct: 139 YKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 167
Score = 33.9 bits (76), Expect = 0.32
Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 66 RARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSA 125
+A++++ QQQQ+QQ QQ Q+Q Q Q+ QQ+ +L S P QA L
Sbjct: 196 QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQA--ALPV 253
Query: 126 SSSPTLPPSPGD 137
S P SP +
Sbjct: 254 QSLPQAGLSPAE 265
Score = 33.1 bits (74), Expect = 0.54
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 23/51 (45%)
Query: 73 QQQQRQ-----------------------QQQQQQQQRQRQQQQQQRRQQE 100
QQQQ QQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 123 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ 173
Score = 32.3 bits (72), Expect = 0.92
Identities = 14/31 (45%), Positives = 24/31 (77%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
+E ++Q++Q Q Q+Q+QQQQQQ++QQ+
Sbjct: 136 QEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQ 166
Score = 32.0 bits (71), Expect = 1.2
Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 22/52 (42%)
Query: 71 EHQQQQR----------------------QQQQQQQQQRQRQQQQQQRRQQE 100
+ QQ QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 123 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 174
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 55.8 bits (133), Expect = 8e-08
Identities = 25/47 (53%), Positives = 36/47 (76%)
Query: 55 HLWFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEP 101
HL + + + + ++ QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ P
Sbjct: 55 HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP 101
Score = 53.1 bits (126), Expect = 5e-07
Identities = 28/58 (48%), Positives = 39/58 (67%), Gaps = 2/58 (3%)
Query: 68 RDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSA 125
+ ++ QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+ P A E Q + L+A
Sbjct: 65 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAK--EQQQQQQQQQQLAA 120
Score = 49.3 bits (116), Expect = 7e-06
Identities = 24/46 (52%), Positives = 31/46 (67%)
Query: 74 QQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQA 119
QQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+ + P QA
Sbjct: 60 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 105
Score = 45.4 bits (106), Expect = 1e-04
Identities = 20/35 (57%), Positives = 30/35 (85%)
Query: 66 RARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
+ +++ H Q +QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 49 KQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 83
Score = 40.0 bits (92), Expect = 0.004
Identities = 20/33 (60%), Positives = 27/33 (81%), Gaps = 2/33 (6%)
Query: 70 KEHQQQQRQQ--QQQQQQQRQRQQQQQQRRQQE 100
K+ Q+Q Q QQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 48 KKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 80
Score = 39.3 bits (90), Expect = 0.008
Identities = 29/77 (37%), Positives = 37/77 (48%), Gaps = 12/77 (15%)
Query: 68 RDKEHQQQQRQQQQQQQ--------QQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQA 119
+ ++ QQQQ+QQQQQQQ QQ+Q+QQQQQ QQ LL + Q
Sbjct: 83 QQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL----QMQQLQQQ 138
Query: 120 HRLLSASSSPTLPPSPG 136
LLS + PG
Sbjct: 139 QHLLSLQRQGLISIPPG 155
Score = 34.3 bits (77), Expect = 0.24
Identities = 15/29 (51%), Positives = 23/29 (79%)
Query: 72 HQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
+++QQ Q Q QQ+Q+QQQQQQ++QQ+
Sbjct: 47 YKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 75
Score = 33.9 bits (76), Expect = 0.32
Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 66 RARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSA 125
+A++++ QQQQ+QQ QQ Q+Q Q Q+ QQ+ +L S P QA L
Sbjct: 104 QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQA--ALPV 161
Query: 126 SSSPTLPPSPGD 137
S P SP +
Sbjct: 162 QSLPQAGLSPAE 173
Score = 33.1 bits (74), Expect = 0.54
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 23/51 (45%)
Query: 73 QQQQRQ-----------------------QQQQQQQQRQRQQQQQQRRQQE 100
QQQQ QQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 31 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ 81
Score = 32.3 bits (72), Expect = 0.92
Identities = 14/31 (45%), Positives = 24/31 (77%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
+E ++Q++Q Q Q+Q+QQQQQQ++QQ+
Sbjct: 44 QEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQ 74
Score = 32.0 bits (71), Expect = 1.2
Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 22/52 (42%)
Query: 71 EHQQQQR----------------------QQQQQQQQQRQRQQQQQQRRQQE 100
+ QQ QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 31 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 82
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 55.8 bits (133), Expect = 8e-08
Identities = 25/47 (53%), Positives = 36/47 (76%)
Query: 55 HLWFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEP 101
HL + + + + ++ QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ P
Sbjct: 172 HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP 218
Score = 53.1 bits (126), Expect = 5e-07
Identities = 28/58 (48%), Positives = 39/58 (67%), Gaps = 2/58 (3%)
Query: 68 RDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSA 125
+ ++ QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+ P A E Q + L+A
Sbjct: 182 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAK--EQQQQQQQQQQLAA 237
Score = 49.3 bits (116), Expect = 7e-06
Identities = 24/46 (52%), Positives = 31/46 (67%)
Query: 74 QQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQA 119
QQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+ + P QA
Sbjct: 177 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 222
Score = 45.4 bits (106), Expect = 1e-04
Identities = 20/35 (57%), Positives = 30/35 (85%)
Query: 66 RARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
+ +++ H Q +QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 166 KQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 200
Score = 40.0 bits (92), Expect = 0.004
Identities = 20/33 (60%), Positives = 27/33 (81%), Gaps = 2/33 (6%)
Query: 70 KEHQQQQRQQ--QQQQQQQRQRQQQQQQRRQQE 100
K+ Q+Q Q QQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 165 KKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 197
Score = 39.3 bits (90), Expect = 0.008
Identities = 29/77 (37%), Positives = 37/77 (48%), Gaps = 12/77 (15%)
Query: 68 RDKEHQQQQRQQQQQQQ--------QQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQA 119
+ ++ QQQQ+QQQQQQQ QQ+Q+QQQQQ QQ LL + Q
Sbjct: 200 QQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL----QMQQLQQQ 255
Query: 120 HRLLSASSSPTLPPSPG 136
LLS + PG
Sbjct: 256 QHLLSLQRQGLISIPPG 272
Score = 34.3 bits (77), Expect = 0.24
Identities = 15/29 (51%), Positives = 23/29 (79%)
Query: 72 HQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
+++QQ Q Q QQ+Q+QQQQQQ++QQ+
Sbjct: 164 YKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 192
Score = 33.9 bits (76), Expect = 0.32
Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 66 RARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSA 125
+A++++ QQQQ+QQ QQ Q+Q Q Q+ QQ+ +L S P QA L
Sbjct: 221 QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQA--ALPV 278
Query: 126 SSSPTLPPSPGD 137
S P SP +
Sbjct: 279 QSLPQAGLSPAE 290
Score = 33.1 bits (74), Expect = 0.54
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 23/51 (45%)
Query: 73 QQQQRQ-----------------------QQQQQQQQRQRQQQQQQRRQQE 100
QQQQ QQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ 198
Score = 32.3 bits (72), Expect = 0.92
Identities = 14/31 (45%), Positives = 24/31 (77%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
+E ++Q++Q Q Q+Q+QQQQQQ++QQ+
Sbjct: 161 QEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQ 191
Score = 32.0 bits (71), Expect = 1.2
Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 22/52 (42%)
Query: 71 EHQQQQR----------------------QQQQQQQQQRQRQQQQQQRRQQE 100
+ QQ QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 199
>gi|189491748 ataxin 1 [Homo sapiens]
Length = 815
Score = 55.5 bits (132), Expect = 1e-07
Identities = 31/60 (51%), Positives = 42/60 (70%), Gaps = 1/60 (1%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSP 129
++ QQQQ+QQQQQ Q Q+Q+QQQQQQ++QQ S L + G S P AQ ++ + SSSP
Sbjct: 196 EQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPG-SPPPAQQNQYVHISSSP 254
>gi|51479158 ataxin 1 [Homo sapiens]
Length = 815
Score = 55.5 bits (132), Expect = 1e-07
Identities = 31/60 (51%), Positives = 42/60 (70%), Gaps = 1/60 (1%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSP 129
++ QQQQ+QQQQQ Q Q+Q+QQQQQQ++QQ S L + G S P AQ ++ + SSSP
Sbjct: 196 EQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPG-SPPPAQQNQYVHISSSP 254
>gi|90903231 huntingtin [Homo sapiens]
Length = 3144
Score = 54.7 bits (130), Expect = 2e-07
Identities = 33/76 (43%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 63 KLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRL 122
KL +A + QQ+QQQQQQQQQ+Q+QQQQQQ++ P P + + P QA L
Sbjct: 6 KLMKAFESLKSFQQQQQQQQQQQQQQQQQQQQQQQPPPPPPPPPPPQLPQ--PPPQAQPL 63
Query: 123 LSASSSPTLPPSPGDG 138
L P PP P G
Sbjct: 64 LPQPQPPPPPPPPPPG 79
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 54.7 bits (130), Expect = 2e-07
Identities = 35/72 (48%), Positives = 42/72 (58%), Gaps = 8/72 (11%)
Query: 73 QQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTLP 132
QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+ AL+ S Q R P L
Sbjct: 523 QQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLR------QPNLA 576
Query: 133 P--SPGDGGGGG 142
PGD G GG
Sbjct: 577 QLGHPGDVGQGG 588
Score = 48.1 bits (113), Expect = 2e-05
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 10/95 (10%)
Query: 64 LTRARDKEHQQQQRQQQQQQQQQRQRQQQQQ----------QRRQQEPSWPALLASMGES 113
L + + ++ QQQQ+QQQQQQQQQ+Q+QQQ+Q R QQ+ LA +G
Sbjct: 522 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHP 581
Query: 114 SPAAQAHRLLSASSSPTLPPSPGDGGGGGGKGNRG 148
Q + P+ GG G G G
Sbjct: 582 GDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLG 616
Score = 39.7 bits (91), Expect = 0.006
Identities = 17/30 (56%), Positives = 23/30 (76%)
Query: 71 EHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
+H Q QQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 513 QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQ 542
Score = 31.2 bits (69), Expect = 2.0
Identities = 14/23 (60%), Positives = 17/23 (73%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQ 92
K H Q +QQ QQQQQ +Q+QQQ
Sbjct: 287 KMHAQPPQQQPQQQQQPQQQQQQ 309
Score = 29.6 bits (65), Expect = 6.0
Identities = 20/58 (34%), Positives = 24/58 (41%)
Query: 76 QRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTLPP 133
Q QQQ QQQQ+ +QQQQQ E A +G H L+ PP
Sbjct: 291 QPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPP 348
Score = 29.6 bits (65), Expect = 6.0
Identities = 14/19 (73%), Positives = 15/19 (78%)
Query: 75 QQRQQQQQQQQQRQRQQQQ 93
Q QQQ QQQQQ Q+QQQQ
Sbjct: 291 QPPQQQPQQQQQPQQQQQQ 309
>gi|171543895 ataxin 2 [Homo sapiens]
Length = 1313
Score = 54.3 bits (129), Expect = 2e-07
Identities = 33/93 (35%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Query: 64 LTRARDKEHQQQQRQQQQQQQQQRQRQQQQ---QQRRQQEPSWPALLASMGESSPAAQAH 120
LT + + QQQQ+QQQQQQQQQ+Q+QQQQ ++P LLAS + + +
Sbjct: 159 LTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSS 218
Query: 121 RLLSASSSPTLPPSPGDGGGGGGKGNRGKDDRG 153
S++++P+ + GGG G G ++G
Sbjct: 219 VSSSSATAPSSVVAATSGGGRPGLGRGRNSNKG 251
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 53.9 bits (128), Expect = 3e-07
Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 13/86 (15%)
Query: 60 AEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQ----------RRQQEPSWPALLAS 109
A +L R + ++ QQQQ+QQQQQQQQQ+Q+QQQQQQ + Q + PA + +
Sbjct: 2712 AHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKA 2771
Query: 110 MGESSPAAQAHRLLSASSSPTLPPSP 135
+G+ +P H + +PP P
Sbjct: 2772 VGKLTP---EHLIKMQKQKLQMPPQP 2794
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 53.1 bits (126), Expect = 5e-07
Identities = 23/44 (52%), Positives = 36/44 (81%)
Query: 61 EAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWP 104
+ ++ R + ++ QQQQ+QQQQQQQQQ+Q+QQQ QQ++QQ+ + P
Sbjct: 2084 QQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPP 2127
Score = 52.8 bits (125), Expect = 7e-07
Identities = 27/53 (50%), Positives = 35/53 (66%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRL 122
++ QQQQ+QQQQQQQQQ+Q+QQQQQQ +QQ+ A +S P Q L
Sbjct: 2090 QQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGL 2142
Score = 50.1 bits (118), Expect = 4e-06
Identities = 22/37 (59%), Positives = 30/37 (81%)
Query: 68 RDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWP 104
+ ++ QQQQ+QQQQQQQQQ+Q+Q QQQQ++Q P P
Sbjct: 2093 QQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQP 2129
Score = 49.3 bits (116), Expect = 7e-06
Identities = 24/46 (52%), Positives = 33/46 (71%)
Query: 73 QQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQ 118
+QQQ+QQQQQQQQQ+Q+QQQQQQ++QQ A+ + P +Q
Sbjct: 2089 RQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQ 2134
Score = 48.5 bits (114), Expect = 1e-05
Identities = 22/33 (66%), Positives = 29/33 (87%)
Query: 68 RDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
R ++ QQ RQQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 2080 RQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQ 2112
Score = 47.8 bits (112), Expect = 2e-05
Identities = 25/44 (56%), Positives = 33/44 (75%), Gaps = 3/44 (6%)
Query: 60 AEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQR---RQQE 100
A + T ++ QQQQ+QQQQQQQQQ+Q+QQQQQQ+ RQQ+
Sbjct: 2040 AGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQ 2083
Score = 46.6 bits (109), Expect = 5e-05
Identities = 22/39 (56%), Positives = 30/39 (76%)
Query: 62 AKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
A L + ++ QQQQ+QQQQQQQQQ+Q+QQQ R+QQ+
Sbjct: 2046 AILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQ 2084
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/53 (45%), Positives = 34/53 (64%), Gaps = 13/53 (24%)
Query: 61 EAKLTRARDKEHQQQQRQQQQQQQQQ-------------RQRQQQQQQRRQQE 100
E + + + ++ QQQQ+QQQQQQQQQ RQ+QQQQQQ++QQ+
Sbjct: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQ 2102
Score = 43.1 bits (100), Expect = 5e-04
Identities = 18/28 (64%), Positives = 26/28 (92%)
Query: 76 QRQQQQQQQQQRQRQQQQQQRRQQEPSW 103
++QQQQQQQQQ+Q+QQQQQQ++QQ+ +
Sbjct: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQY 2077
Score = 42.7 bits (99), Expect = 7e-04
Identities = 19/34 (55%), Positives = 26/34 (76%)
Query: 68 RDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEP 101
+ ++ QQQQ+QQQQQQQQ +Q+QQQQ Q +P
Sbjct: 2098 QQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQP 2131
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/39 (58%), Positives = 31/39 (79%), Gaps = 6/39 (15%)
Query: 68 RDKEHQQQQ---RQQQQQQ---QQQRQRQQQQQQRRQQE 100
+ ++ QQQQ RQQQQQQ QQQ+Q+QQQQQQ++QQ+
Sbjct: 2068 QQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQ 2106
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 5/72 (6%)
Query: 68 RDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWP-----ALLASMGESSPAAQAHRL 122
+ ++ QQQQ+QQQQQQQ Q+Q+QQQ + Q S P L + + AA +L
Sbjct: 2099 QQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQL 2158
Query: 123 LSASSSPTLPPS 134
S+ PS
Sbjct: 2159 QQQLSNTQPQPS 2170
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 52.0 bits (123), Expect = 1e-06
Identities = 23/28 (82%), Positives = 28/28 (100%)
Query: 72 HQQQQRQQQQQQQQQRQRQQQQQQRRQQ 99
HQQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ
Sbjct: 459 HQQQQQQQQQQQQQQQQQQQQQQQQQQQ 486
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/93 (37%), Positives = 46/93 (49%), Gaps = 16/93 (17%)
Query: 57 WFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALL--ASMGESS 114
W + L + QQQQ+QQQQQQQQQ+Q+QQQQQQ++ LL A M +
Sbjct: 446 WRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQ 505
Query: 115 PAAQAHRLL--------------SASSSPTLPP 133
A Q ++L SAS PT+ P
Sbjct: 506 HATQQQQMLQQQFLMHSVYQPQPSASQYPTMMP 538
Score = 30.8 bits (68), Expect = 2.7
Identities = 14/37 (37%), Positives = 24/37 (64%)
Query: 64 LTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
L + + + + QQ Q + Q+Q+QQQQQQ++QQ+
Sbjct: 438 LQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQ 474
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 52.0 bits (123), Expect = 1e-06
Identities = 23/28 (82%), Positives = 28/28 (100%)
Query: 72 HQQQQRQQQQQQQQQRQRQQQQQQRRQQ 99
HQQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ
Sbjct: 459 HQQQQQQQQQQQQQQQQQQQQQQQQQQQ 486
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/93 (37%), Positives = 46/93 (49%), Gaps = 16/93 (17%)
Query: 57 WFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALL--ASMGESS 114
W + L + QQQQ+QQQQQQQQQ+Q+QQQQQQ++ LL A M +
Sbjct: 446 WRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQ 505
Query: 115 PAAQAHRLL--------------SASSSPTLPP 133
A Q ++L SAS PT+ P
Sbjct: 506 HATQQQQMLQQQFLMHSVYQPQPSASQYPTMMP 538
Score = 30.8 bits (68), Expect = 2.7
Identities = 14/37 (37%), Positives = 24/37 (64%)
Query: 64 LTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
L + + + + QQ Q + Q+Q+QQQQQQ++QQ+
Sbjct: 438 LQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQ 474
>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
Length = 796
Score = 52.0 bits (123), Expect = 1e-06
Identities = 34/85 (40%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 60 AEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLAS---------M 110
A A A ++ QQQQ+QQQQQQQQQ+Q+QQQQQ S PA+LA+
Sbjct: 93 AAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLS 152
Query: 111 GESSPAAQAHRLLSASSSPTLPPSP 135
++ AA A + S PP P
Sbjct: 153 AAAAAAAAAAAAVEQRSRFEYPPPP 177
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 51.2 bits (121), Expect = 2e-06
Identities = 29/64 (45%), Positives = 42/64 (65%), Gaps = 5/64 (7%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSP 129
++ QQQQ+QQQQQQQQQ+Q+QQQQQQ++Q + P + +SP+ LL+ + P
Sbjct: 1248 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVT---ASPSMDG--LLAGPTMP 1302
Query: 130 TLPP 133
PP
Sbjct: 1303 QAPP 1306
Score = 39.7 bits (91), Expect = 0.006
Identities = 19/39 (48%), Positives = 27/39 (69%)
Query: 62 AKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
A+ +R H +QQR QQQQ+Q+QQQQQQ++QQ+
Sbjct: 1227 AQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQ 1265
Score = 31.6 bits (70), Expect = 1.6
Identities = 20/78 (25%), Positives = 34/78 (43%), Gaps = 6/78 (7%)
Query: 62 AKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHR 121
A++ R +E +QQ+ +Q+QQQQQQ++QQ+ + Q +
Sbjct: 1223 AQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQ------QQQQQQQQQQQQQ 1276
Query: 122 LLSASSSPTLPPSPGDGG 139
+ S P + SP G
Sbjct: 1277 TQAFSPPPNVTASPSMDG 1294
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 51.2 bits (121), Expect = 2e-06
Identities = 29/64 (45%), Positives = 42/64 (65%), Gaps = 5/64 (7%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSP 129
++ QQQQ+QQQQQQQQQ+Q+QQQQQQ++Q + P + +SP+ LL+ + P
Sbjct: 1244 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVT---ASPSMDG--LLAGPTMP 1298
Query: 130 TLPP 133
PP
Sbjct: 1299 QAPP 1302
Score = 39.7 bits (91), Expect = 0.006
Identities = 19/39 (48%), Positives = 27/39 (69%)
Query: 62 AKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
A+ +R H +QQR QQQQ+Q+QQQQQQ++QQ+
Sbjct: 1223 AQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQ 1261
Score = 31.6 bits (70), Expect = 1.6
Identities = 20/78 (25%), Positives = 34/78 (43%), Gaps = 6/78 (7%)
Query: 62 AKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHR 121
A++ R +E +QQ+ +Q+QQQQQQ++QQ+ + Q +
Sbjct: 1219 AQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQ------QQQQQQQQQQQQQ 1272
Query: 122 LLSASSSPTLPPSPGDGG 139
+ S P + SP G
Sbjct: 1273 TQAFSPPPNVTASPSMDG 1290
>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1662
Score = 51.2 bits (121), Expect = 2e-06
Identities = 24/48 (50%), Positives = 37/48 (77%)
Query: 51 LLSDHLWFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQ 98
++ ++ + A+ + AR+ QQQQ+QQQQQQQQQ+Q+QQQQQQ++Q
Sbjct: 1581 VVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
Score = 49.3 bits (116), Expect = 7e-06
Identities = 22/28 (78%), Positives = 28/28 (100%)
Query: 72 HQQQQRQQQQQQQQQRQRQQQQQQRRQQ 99
+QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ
Sbjct: 1601 NQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
Score = 47.8 bits (112), Expect = 2e-05
Identities = 21/27 (77%), Positives = 27/27 (100%)
Query: 74 QQQRQQQQQQQQQRQRQQQQQQRRQQE 100
QQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQ 1628
Score = 46.2 bits (108), Expect = 6e-05
Identities = 22/42 (52%), Positives = 30/42 (71%)
Query: 76 QRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAA 117
Q+QQQQQQQQQ+Q+QQQQQQ++QQ+ A + E P +
Sbjct: 1602 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGS 1643
Score = 45.4 bits (106), Expect = 1e-04
Identities = 21/37 (56%), Positives = 29/37 (78%)
Query: 64 LTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
L RA ++ + QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 1588 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ 1624
Score = 45.4 bits (106), Expect = 1e-04
Identities = 23/52 (44%), Positives = 31/52 (59%)
Query: 64 LTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSP 115
L A + + +QQQQQQQQQ+Q+QQQQQQ++QQ+ A A P
Sbjct: 1589 LRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1640
Score = 34.3 bits (77), Expect = 0.24
Identities = 18/58 (31%), Positives = 32/58 (55%)
Query: 74 QQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTL 131
++ + QQQQ+Q+QQQQQQ++QQ+ + ++ AA H S +S+ +
Sbjct: 1593 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVM 1650
>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 51.2 bits (121), Expect = 2e-06
Identities = 24/48 (50%), Positives = 37/48 (77%)
Query: 51 LLSDHLWFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQ 98
++ ++ + A+ + AR+ QQQQ+QQQQQQQQQ+Q+QQQQQQ++Q
Sbjct: 1729 VVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
Score = 49.3 bits (116), Expect = 7e-06
Identities = 22/28 (78%), Positives = 28/28 (100%)
Query: 72 HQQQQRQQQQQQQQQRQRQQQQQQRRQQ 99
+QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ
Sbjct: 1749 NQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
Score = 47.8 bits (112), Expect = 2e-05
Identities = 21/27 (77%), Positives = 27/27 (100%)
Query: 74 QQQRQQQQQQQQQRQRQQQQQQRRQQE 100
QQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
Score = 46.2 bits (108), Expect = 6e-05
Identities = 22/42 (52%), Positives = 30/42 (71%)
Query: 76 QRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAA 117
Q+QQQQQQQQQ+Q+QQQQQQ++QQ+ A + E P +
Sbjct: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGS 1791
Score = 45.4 bits (106), Expect = 1e-04
Identities = 21/37 (56%), Positives = 29/37 (78%)
Query: 64 LTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
L RA ++ + QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 1736 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ 1772
Score = 45.4 bits (106), Expect = 1e-04
Identities = 23/52 (44%), Positives = 31/52 (59%)
Query: 64 LTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSP 115
L A + + +QQQQQQQQQ+Q+QQQQQQ++QQ+ A A P
Sbjct: 1737 LRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1788
Score = 34.3 bits (77), Expect = 0.24
Identities = 18/58 (31%), Positives = 32/58 (55%)
Query: 74 QQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTL 131
++ + QQQQ+Q+QQQQQQ++QQ+ + ++ AA H S +S+ +
Sbjct: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVM 1798
>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 51.2 bits (121), Expect = 2e-06
Identities = 24/48 (50%), Positives = 37/48 (77%)
Query: 51 LLSDHLWFCAEAKLTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQ 98
++ ++ + A+ + AR+ QQQQ+QQQQQQQQQ+Q+QQQQQQ++Q
Sbjct: 1729 VVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
Score = 49.3 bits (116), Expect = 7e-06
Identities = 22/28 (78%), Positives = 28/28 (100%)
Query: 72 HQQQQRQQQQQQQQQRQRQQQQQQRRQQ 99
+QQQQ+QQQQQQQQQ+Q+QQQQQQ++QQ
Sbjct: 1749 NQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
Score = 47.8 bits (112), Expect = 2e-05
Identities = 21/27 (77%), Positives = 27/27 (100%)
Query: 74 QQQRQQQQQQQQQRQRQQQQQQRRQQE 100
QQQ+QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
Score = 46.2 bits (108), Expect = 6e-05
Identities = 22/42 (52%), Positives = 30/42 (71%)
Query: 76 QRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAA 117
Q+QQQQQQQQQ+Q+QQQQQQ++QQ+ A + E P +
Sbjct: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGS 1791
Score = 45.4 bits (106), Expect = 1e-04
Identities = 21/37 (56%), Positives = 29/37 (78%)
Query: 64 LTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE 100
L RA ++ + QQQQQQQQQ+Q+QQQQQQ++QQ+
Sbjct: 1736 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ 1772
Score = 45.4 bits (106), Expect = 1e-04
Identities = 23/52 (44%), Positives = 31/52 (59%)
Query: 64 LTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSP 115
L A + + +QQQQQQQQQ+Q+QQQQQQ++QQ+ A A P
Sbjct: 1737 LRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1788
Score = 34.3 bits (77), Expect = 0.24
Identities = 18/58 (31%), Positives = 32/58 (55%)
Query: 74 QQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTL 131
++ + QQQQ+Q+QQQQQQ++QQ+ + ++ AA H S +S+ +
Sbjct: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVM 1798
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 48.9 bits (115), Expect = 9e-06
Identities = 22/34 (64%), Positives = 27/34 (79%)
Query: 73 QQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPAL 106
Q+QQ+QQQQQQQQQ+Q+QQQQQQ Q +W L
Sbjct: 484 QKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPL 517
Score = 48.1 bits (113), Expect = 2e-05
Identities = 29/75 (38%), Positives = 40/75 (53%), Gaps = 7/75 (9%)
Query: 66 RARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQE-------PSWPALLASMGESSPAAQ 118
RA+ + +QQQ+QQQQQQQQQ+Q+QQQQQ Q PS P A E +
Sbjct: 478 RAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPM 537
Query: 119 AHRLLSASSSPTLPP 133
+ + +P +PP
Sbjct: 538 MYPQAFNNQNPIVPP 552
Score = 44.3 bits (103), Expect = 2e-04
Identities = 23/35 (65%), Positives = 29/35 (82%), Gaps = 5/35 (14%)
Query: 73 QQQQR-----QQQQQQQQQRQRQQQQQQRRQQEPS 102
QQQQR Q+QQQQQQQ+Q+QQQQQQ++QQ+ S
Sbjct: 474 QQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHS 508
Score = 37.7 bits (86), Expect = 0.022
Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 11/71 (15%)
Query: 64 LTRARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLL 123
++ A + Q+QQ+ + QQ+Q+QQQQQQ++QQ+ + Q H
Sbjct: 462 MSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQ-----------QQQQQQQQHSNQ 510
Query: 124 SASSSPTLPPS 134
+++ SP PPS
Sbjct: 511 TSNWSPLGPPS 521
Score = 37.4 bits (85), Expect = 0.029
Identities = 17/26 (65%), Positives = 22/26 (84%)
Query: 83 QQQQRQRQQQQQQRRQQEPSWPALLA 108
QQQQ+Q+QQQQQQ++QQ+P P L A
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQA 654
Score = 37.0 bits (84), Expect = 0.037
Identities = 18/33 (54%), Positives = 23/33 (69%)
Query: 80 QQQQQQQRQRQQQQQQRRQQEPSWPALLASMGE 112
QQQQQQQ+Q+QQQQQQ++ P A A + E
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSE 661
Score = 36.6 bits (83), Expect = 0.049
Identities = 17/27 (62%), Positives = 21/27 (77%)
Query: 75 QQRQQQQQQQQQRQRQQQQQQRRQQEP 101
QQ+QQQQQQQQQ+Q+QQQ + Q P
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQAP 655
Score = 35.0 bits (79), Expect = 0.14
Identities = 16/23 (69%), Positives = 19/23 (82%)
Query: 73 QQQQRQQQQQQQQQRQRQQQQQQ 95
QQQQ+QQQQQQQQQ+Q+Q Q
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQ 651
Score = 34.3 bits (77), Expect = 0.24
Identities = 16/25 (64%), Positives = 19/25 (76%)
Query: 71 EHQQQQRQQQQQQQQQRQRQQQQQQ 95
+ QQQQ+QQQQQQQQQ+Q Q Q
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQ 653
Score = 33.5 bits (75), Expect = 0.41
Identities = 16/28 (57%), Positives = 20/28 (71%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQQQRR 97
++ QQQQ+QQQQQQQQQ+ Q Q R
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQAPR 656
Score = 33.1 bits (74), Expect = 0.54
Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 6/60 (10%)
Query: 62 AKLTRARDKEHQQQQRQQQQQQQQ---QRQRQQQQQQRRQQEPS---WPALLASMGESSP 115
A+L + ++ ++QRQQQQQQQQ ++Q QQ R+ +P +P + + SP
Sbjct: 744 AQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSP 803
Score = 31.6 bits (70), Expect = 1.6
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 16/94 (17%)
Query: 68 RDKEHQQQQRQQQQQQQQQRQRQQQ-------QQQRR---------QQEPSWPALLASMG 111
+ ++ QQQQ+QQQQQQQQ Q Q + Q+R +P A L S G
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHG 688
Query: 112 ESSPAAQAHRLLSASSSPTLPPSPGDGGGGGGKG 145
+ R S P S G G G
Sbjct: 689 QEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAG 722
Score = 31.6 bits (70), Expect = 1.6
Identities = 16/34 (47%), Positives = 25/34 (73%)
Query: 66 RARDKEHQQQQRQQQQQQQQQRQRQQQQQQRRQQ 99
RA+ E Q+QQ ++Q+QQQQ+Q+Q +Q+ QQ
Sbjct: 743 RAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQ 776
>gi|226442791 runt-related transcription factor 2 isoform b [Homo
sapiens]
Length = 499
Score = 48.1 bits (113), Expect = 2e-05
Identities = 25/54 (46%), Positives = 36/54 (66%)
Query: 78 QQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTL 131
QQQQQQQQQ+Q+QQQQQQ++QQ+ + A A+ ++ AA RL + T+
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTM 102
Score = 47.0 bits (110), Expect = 4e-05
Identities = 23/41 (56%), Positives = 32/41 (78%)
Query: 77 RQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAA 117
+QQQQQQQQQ+Q+QQQQQQ++QQE + A A+ ++ AA
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAA 89
Score = 45.4 bits (106), Expect = 1e-04
Identities = 23/43 (53%), Positives = 29/43 (67%)
Query: 73 QQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSP 115
QQQQ+QQQQQQQQQ+Q+QQQQQQ + A A+ + P
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVP 91
Score = 42.0 bits (97), Expect = 0.001
Identities = 18/24 (75%), Positives = 23/24 (95%)
Query: 71 EHQQQQRQQQQQQQQQRQRQQQQQ 94
+ QQQQ+QQQQQQQQQ+Q+QQQQ+
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQE 72
Score = 40.4 bits (93), Expect = 0.003
Identities = 17/24 (70%), Positives = 23/24 (95%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQ 93
++ QQQQ+QQQQQQQQQ+Q+QQQ+
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQE 72
Score = 39.7 bits (91), Expect = 0.006
Identities = 17/26 (65%), Positives = 23/26 (88%)
Query: 67 ARDKEHQQQQRQQQQQQQQQRQRQQQ 92
A ++ QQQQ+QQQQQQQQQ+Q+QQ+
Sbjct: 47 AAQQQQQQQQQQQQQQQQQQQQQQQE 72
Score = 31.2 bits (69), Expect = 2.0
Identities = 13/25 (52%), Positives = 20/25 (80%)
Query: 62 AKLTRARDKEHQQQQRQQQQQQQQQ 86
A+ + + ++ QQQQ+QQQQQQQQ+
Sbjct: 48 AQQQQQQQQQQQQQQQQQQQQQQQE 72
Score = 29.6 bits (65), Expect = 6.0
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 87 RQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTLPP 133
+Q+QQQQQQ++QQ+ ++ AA A +A++ P L P
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRP 95
>gi|226442783 runt-related transcription factor 2 isoform a [Homo
sapiens]
Length = 521
Score = 48.1 bits (113), Expect = 2e-05
Identities = 25/54 (46%), Positives = 36/54 (66%)
Query: 78 QQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTL 131
QQQQQQQQQ+Q+QQQQQQ++QQ+ + A A+ ++ AA RL + T+
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTM 102
Score = 47.0 bits (110), Expect = 4e-05
Identities = 23/41 (56%), Positives = 32/41 (78%)
Query: 77 RQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAA 117
+QQQQQQQQQ+Q+QQQQQQ++QQE + A A+ ++ AA
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAA 89
Score = 45.4 bits (106), Expect = 1e-04
Identities = 23/43 (53%), Positives = 29/43 (67%)
Query: 73 QQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSP 115
QQQQ+QQQQQQQQQ+Q+QQQQQQ + A A+ + P
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVP 91
Score = 42.0 bits (97), Expect = 0.001
Identities = 18/24 (75%), Positives = 23/24 (95%)
Query: 71 EHQQQQRQQQQQQQQQRQRQQQQQ 94
+ QQQQ+QQQQQQQQQ+Q+QQQQ+
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQE 72
Score = 40.4 bits (93), Expect = 0.003
Identities = 17/24 (70%), Positives = 23/24 (95%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQ 93
++ QQQQ+QQQQQQQQQ+Q+QQQ+
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQE 72
Score = 39.7 bits (91), Expect = 0.006
Identities = 17/26 (65%), Positives = 23/26 (88%)
Query: 67 ARDKEHQQQQRQQQQQQQQQRQRQQQ 92
A ++ QQQQ+QQQQQQQQQ+Q+QQ+
Sbjct: 47 AAQQQQQQQQQQQQQQQQQQQQQQQE 72
Score = 31.2 bits (69), Expect = 2.0
Identities = 13/25 (52%), Positives = 20/25 (80%)
Query: 62 AKLTRARDKEHQQQQRQQQQQQQQQ 86
A+ + + ++ QQQQ+QQQQQQQQ+
Sbjct: 48 AQQQQQQQQQQQQQQQQQQQQQQQE 72
Score = 29.6 bits (65), Expect = 6.0
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 87 RQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTLPP 133
+Q+QQQQQQ++QQ+ ++ AA A +A++ P L P
Sbjct: 49 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRP 95
>gi|66934969 runt-related transcription factor 2 isoform c [Homo
sapiens]
Length = 507
Score = 48.1 bits (113), Expect = 2e-05
Identities = 25/54 (46%), Positives = 36/54 (66%)
Query: 78 QQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTL 131
QQQQQQQQQ+Q+QQQQQQ++QQ+ + A A+ ++ AA RL + T+
Sbjct: 35 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTM 88
Score = 47.0 bits (110), Expect = 4e-05
Identities = 23/41 (56%), Positives = 32/41 (78%)
Query: 77 RQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSPAA 117
+QQQQQQQQQ+Q+QQQQQQ++QQE + A A+ ++ AA
Sbjct: 35 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAA 75
Score = 45.4 bits (106), Expect = 1e-04
Identities = 23/43 (53%), Positives = 29/43 (67%)
Query: 73 QQQQRQQQQQQQQQRQRQQQQQQRRQQEPSWPALLASMGESSP 115
QQQQ+QQQQQQQQQ+Q+QQQQQQ + A A+ + P
Sbjct: 35 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVP 77
Score = 42.0 bits (97), Expect = 0.001
Identities = 18/24 (75%), Positives = 23/24 (95%)
Query: 71 EHQQQQRQQQQQQQQQRQRQQQQQ 94
+ QQQQ+QQQQQQQQQ+Q+QQQQ+
Sbjct: 35 QQQQQQQQQQQQQQQQQQQQQQQE 58
Score = 40.4 bits (93), Expect = 0.003
Identities = 17/24 (70%), Positives = 23/24 (95%)
Query: 70 KEHQQQQRQQQQQQQQQRQRQQQQ 93
++ QQQQ+QQQQQQQQQ+Q+QQQ+
Sbjct: 35 QQQQQQQQQQQQQQQQQQQQQQQE 58
Score = 39.7 bits (91), Expect = 0.006
Identities = 17/26 (65%), Positives = 23/26 (88%)
Query: 67 ARDKEHQQQQRQQQQQQQQQRQRQQQ 92
A ++ QQQQ+QQQQQQQQQ+Q+QQ+
Sbjct: 33 AAQQQQQQQQQQQQQQQQQQQQQQQE 58
Score = 31.2 bits (69), Expect = 2.0
Identities = 13/25 (52%), Positives = 20/25 (80%)
Query: 62 AKLTRARDKEHQQQQRQQQQQQQQQ 86
A+ + + ++ QQQQ+QQQQQQQQ+
Sbjct: 34 AQQQQQQQQQQQQQQQQQQQQQQQE 58
Score = 29.6 bits (65), Expect = 6.0
Identities = 16/47 (34%), Positives = 26/47 (55%)
Query: 87 RQRQQQQQQRRQQEPSWPALLASMGESSPAAQAHRLLSASSSPTLPP 133
+Q+QQQQQQ++QQ+ ++ AA A +A++ P L P
Sbjct: 35 QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRP 81
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,561,108
Number of Sequences: 37866
Number of extensions: 993788
Number of successful extensions: 24813
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 364
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 11551
Number of HSP's gapped (non-prelim): 6595
length of query: 458
length of database: 18,247,518
effective HSP length: 106
effective length of query: 352
effective length of database: 14,233,722
effective search space: 5010270144
effective search space used: 5010270144
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.