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Search of human proteins with 27363457
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27363457 aarF domain containing kinase 4 isoform a [Homo
sapiens]
(544 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27363457 aarF domain containing kinase 4 isoform a [Homo sapi... 1105 0.0
gi|217416386 aarF domain containing kinase 4 isoform b [Homo sap... 1008 0.0
gi|34147522 chaperone, ABC1 activity of bc1 complex like precurs... 584 e-167
gi|40254938 aarF domain containing kinase 1 isoform a [Homo sapi... 94 4e-19
gi|41393593 aarF domain containing kinase 5 [Homo sapiens] 77 3e-14
gi|217035081 aarF domain containing kinase 1 isoform b [Homo sap... 71 2e-12
gi|32261307 aarF domain containing kinase 2 [Homo sapiens] 44 5e-04
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 35 0.23
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 35 0.23
gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens] 34 0.30
gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens] 34 0.30
gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens] 34 0.30
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens] 32 1.5
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens] 32 1.5
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens] 32 1.5
gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo ... 32 1.9
gi|239748099 PREDICTED: hypothetical protein [Homo sapiens] 32 1.9
gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo ... 32 1.9
gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens] 31 2.5
gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens] 31 2.5
gi|32528297 ribosomal protein S6 kinase, polypeptide 5 isoform b... 31 2.5
gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a... 31 2.5
gi|55743138 ribosomal protein S6 kinase, 90kDa, polypeptide 4 is... 31 3.3
gi|4506735 ribosomal protein S6 kinase, 90kDa, polypeptide 4 iso... 31 3.3
gi|197313667 cell division cycle 7 [Homo sapiens] 30 5.7
gi|197313665 cell division cycle 7 [Homo sapiens] 30 5.7
gi|4502715 cell division cycle 7 [Homo sapiens] 30 5.7
gi|41393599 coproporphyrinogen oxidase [Homo sapiens] 30 7.4
gi|89111943 Kruppel-like factor 8 isoform 1 [Homo sapiens] 29 9.6
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens] 29 9.6
>gi|27363457 aarF domain containing kinase 4 isoform a [Homo
sapiens]
Length = 544
Score = 1105 bits (2858), Expect = 0.0
Identities = 544/544 (100%), Positives = 544/544 (100%)
Query: 1 MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR 60
MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR
Sbjct: 1 MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR 60
Query: 61 RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL 120
RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL
Sbjct: 61 RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL 120
Query: 121 QSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVR 180
QSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVR
Sbjct: 121 QSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVR 180
Query: 181 QSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQY 240
QSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQY
Sbjct: 181 QSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQY 240
Query: 241 PGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQL 300
PGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQL
Sbjct: 241 PGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQL 300
Query: 301 LANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFE 360
LANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFE
Sbjct: 301 LANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFE 360
Query: 361 FRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKS 420
FRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKS
Sbjct: 361 FRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKS 420
Query: 421 RDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCP 480
RDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCP
Sbjct: 421 RDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCP 480
Query: 481 PPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSW 540
PPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSW
Sbjct: 481 PPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSW 540
Query: 541 VDPS 544
VDPS
Sbjct: 541 VDPS 544
>gi|217416386 aarF domain containing kinase 4 isoform b [Homo
sapiens]
Length = 503
Score = 1008 bits (2606), Expect = 0.0
Identities = 503/544 (92%), Positives = 503/544 (92%), Gaps = 41/544 (7%)
Query: 1 MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR 60
MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR
Sbjct: 1 MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIR 60
Query: 61 RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL 120
RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL
Sbjct: 61 RAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRL 120
Query: 121 QSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVR 180
QS DNSFISPQLQHIFERVR
Sbjct: 121 QS-----------------------------------------DNSFISPQLQHIFERVR 139
Query: 181 QSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQY 240
QSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQY
Sbjct: 140 QSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQY 199
Query: 241 PGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQL 300
PGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQL
Sbjct: 200 PGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQL 259
Query: 301 LANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFE 360
LANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFE
Sbjct: 260 LANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFE 319
Query: 361 FRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKS 420
FRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKS
Sbjct: 320 FRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKS 379
Query: 421 RDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCP 480
RDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCP
Sbjct: 380 RDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCP 439
Query: 481 PPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSW 540
PPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSW
Sbjct: 440 PPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSW 499
Query: 541 VDPS 544
VDPS
Sbjct: 500 VDPS 503
>gi|34147522 chaperone, ABC1 activity of bc1 complex like precursor
[Homo sapiens]
Length = 647
Score = 584 bits (1506), Expect = e-167
Identities = 301/517 (58%), Positives = 373/517 (72%), Gaps = 13/517 (2%)
Query: 11 GTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQD-GPGRGLGEEDIRRAREARPR- 68
G GQ +G G L P G + F+QD P GL EDI +AR+A+ R
Sbjct: 129 GFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEKARQAKARP 188
Query: 69 --KTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRLQSEGGS 126
K + LS+ +RERKVP +RI RLANFGGLAVGLG G LAE+AKKS L+SE S
Sbjct: 189 ENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKS-----LRSEDPS 243
Query: 127 G----LDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVRQS 182
G L SSPFLSEANAERIV+TLC VRGAALK+GQMLSIQD++FI+P L IFERVRQS
Sbjct: 244 GKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQS 303
Query: 183 ADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPG 242
ADFMP QM++ L +LG +W+ K+ EE PFAAASIGQVH ++ G EVA+KIQYPG
Sbjct: 304 ADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPG 363
Query: 243 IAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLLA 302
+AQSI SDV NL+AVL MS LP GLF E + L++ELA ECDY+REAACA+ FR LL
Sbjct: 364 VAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRDLLK 423
Query: 303 NDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFEFR 362
PFF VP +V ELC+ VL EL G PLDQ +GLSQ++RN+IC+ +L LCLRELFEF
Sbjct: 424 GHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFH 483
Query: 363 FMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRD 422
FMQTDPNW+NF YD H+V LLDFGA+RE+ FTD YI++++AAAD DR+ V KS +
Sbjct: 484 FMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAKSIE 543
Query: 423 LKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCPPP 482
+KFLTG+E K DAH++A++ILGE FA+ P+DFG+ T +I +LIPV+LRHRL PPP
Sbjct: 544 MKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLVPPP 603
Query: 483 EETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRY 519
EETY+LHRK+ G+FL C+ L+A C+ +F++ Y Y
Sbjct: 604 EETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNY 640
>gi|40254938 aarF domain containing kinase 1 isoform a [Homo
sapiens]
Length = 523
Score = 93.6 bits (231), Expect = 4e-19
Identities = 97/347 (27%), Positives = 154/347 (44%), Gaps = 28/347 (8%)
Query: 94 NFGGLAVGLGLGVLAEMAK------KSMPGGRLQSEGGSGLDSSPFLSEANAERIVQTLC 147
+FG + VG + A ++ KS+P G SE L S L +A R+ + C
Sbjct: 33 DFGAVRVGRAVATTAVISYDYLTSLKSVPYG---SEEYLQLRSKVHLR--SARRLCELCC 87
Query: 148 TVRGAALKVGQMLSIQDNSFISPQLQHIFERVRQSADFMPRWQMLR-VLEEELGRDWQAK 206
RG +KVGQ L D ++ P+ +V S Q +R V+ E+LG++
Sbjct: 88 ANRGTFIKVGQHLGALD--YLLPEEYTSTLKVLHSQAPQSSMQEIRQVIREDLGKEIHDL 145
Query: 207 VASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPA 266
S ++ P AS+ QVH+ +L DG VAVK+Q+P + D+ L+ VL ++
Sbjct: 146 FQSFDDTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSKDIL-LMEVLVLAV---K 201
Query: 267 GLFAEQSLQALQQE----LAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVL 322
LF E L E L E D+ E A+ Q+L + F +VP + +L T RVL
Sbjct: 202 QLFPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFDFLKVPRIHWDLSTERVL 261
Query: 323 GMELAGGVPLDQCQGLSQDL--RNQICFQLLTLCLRELFEFRFMQTDPNWANFLY----D 376
ME G ++ + ++ N+I L + +F F+ DP+ N L
Sbjct: 262 LMEFVDGGQVNDRDYMERNKIDVNEISRHLGKMYSEMIFVNGFVHCDPHPGNVLVRKHPG 321
Query: 377 ASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDL 423
++ LLD G + EF +Y + ++ D V + S+ L
Sbjct: 322 TGKAEIVLLDHGLYQMLTEEFRLNYCHLWQSLIWTDMKRVKEYSQRL 368
>gi|41393593 aarF domain containing kinase 5 [Homo sapiens]
Length = 580
Score = 77.4 bits (189), Expect = 3e-14
Identities = 55/180 (30%), Positives = 87/180 (48%), Gaps = 5/180 (2%)
Query: 214 PFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQS 273
P AAAS+ QVH+ L DGT VAVK+QY + D+ L +L++ +
Sbjct: 205 PIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWV 264
Query: 274 LQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLD 333
LQ L+ LA E D+ E A+ + LA+ P+ VP V + + RVL + G ++
Sbjct: 265 LQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVN 324
Query: 334 QCQGL-SQDLR-NQICFQLLTLCLRELFEFRFMQTDPNWANFLY---DASSHQVTLLDFG 388
+ + SQ L + I +L+ ++F F+ +DP+ N L ++ LLD G
Sbjct: 325 DVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVLLDHG 384
>gi|217035081 aarF domain containing kinase 1 isoform b [Homo
sapiens]
Length = 455
Score = 71.2 bits (173), Expect = 2e-12
Identities = 63/225 (28%), Positives = 101/225 (44%), Gaps = 14/225 (6%)
Query: 209 SLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGL 268
S ++ P AS+ QVH+ +L DG VAVK+Q+P + D+ L+ VL ++ L
Sbjct: 80 SFDDTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSKDIL-LMEVLVLAV---KQL 135
Query: 269 FAEQSLQALQQE----LAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGM 324
F E L E L E D+ E A+ Q+L + F +VP + +L T RVL M
Sbjct: 136 FPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFDFLKVPRIHWDLSTERVLLM 195
Query: 325 ELAGGVPLDQCQGLSQDL--RNQICFQLLTLCLRELFEFRFMQTDPNWANFLY----DAS 378
E G ++ + ++ N+I L + +F F+ DP+ N L
Sbjct: 196 EFVDGGQVNDRDYMERNKIDVNEISRHLGKMYSEMIFVNGFVHCDPHPGNVLVRKHPGTG 255
Query: 379 SHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDL 423
++ LLD G + EF +Y + ++ D V + S+ L
Sbjct: 256 KAEIVLLDHGLYQMLTEEFRLNYCHLWQSLIWTDMKRVKEYSQRL 300
>gi|32261307 aarF domain containing kinase 2 [Homo sapiens]
Length = 626
Score = 43.5 bits (101), Expect = 5e-04
Identities = 39/170 (22%), Positives = 73/170 (42%), Gaps = 6/170 (3%)
Query: 216 AAASIGQV--HQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPA--GLFAE 271
A S QV HQ + VAVK+ +PG+ + D+ + ++ LP L
Sbjct: 288 AGVSRAQVPGHQPEATNLISVAVKVLHPGLLAQVHMDLLLMKIGSRVLGVLPGIKWLSLP 347
Query: 272 QSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVP 331
+ ++ ++ + + D R EA ++F+ N + P ++ T VL VP
Sbjct: 348 EIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEESVP 407
Query: 332 LDQCQ--GLSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASS 379
+ Q G+ DL+ +I + + L+ +F F+ D + N L ++
Sbjct: 408 VSSYQQAGIPVDLKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGAN 457
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 34.7 bits (78), Expect = 0.23
Identities = 41/179 (22%), Positives = 66/179 (36%), Gaps = 30/179 (16%)
Query: 105 GVLAEMAKKSMPG------GRLQSEGGSGLDSSPFLSEANAERIVQTLCTVRGAA-LKVG 157
G E K S P G+++S G + + + N + L ++ L +
Sbjct: 1073 GTSTEPVKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIP 1132
Query: 158 QMLSIQDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAA 217
QM + N +P++Q E + QS + ++ + A SL+E P A
Sbjct: 1133 QMAQLL-NIHSNPEMQQQLEALNQSIS-----ALTEATSQQQDSETMAPEESLKEAPSAP 1186
Query: 218 ASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVL---KMSAALPAGLFAEQS 273
+ Q L A S +D+QN+LAVL M PAG E +
Sbjct: 1187 VILPSAEQTTLE--------------ASSTPADMQNILAVLLSQLMKTQEPAGSLEENN 1231
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 34.7 bits (78), Expect = 0.23
Identities = 41/179 (22%), Positives = 66/179 (36%), Gaps = 30/179 (16%)
Query: 105 GVLAEMAKKSMPG------GRLQSEGGSGLDSSPFLSEANAERIVQTLCTVRGAA-LKVG 157
G E K S P G+++S G + + + N + L ++ L +
Sbjct: 1073 GTSTEPVKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIP 1132
Query: 158 QMLSIQDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAA 217
QM + N +P++Q E + QS + ++ + A SL+E P A
Sbjct: 1133 QMAQLL-NIHSNPEMQQQLEALNQSIS-----ALTEATSQQQDSETMAPEESLKEAPSAP 1186
Query: 218 ASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVL---KMSAALPAGLFAEQS 273
+ Q L A S +D+QN+LAVL M PAG E +
Sbjct: 1187 VILPSAEQTTLE--------------ASSTPADMQNILAVLLSQLMKTQEPAGSLEENN 1231
>gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens]
Length = 4022
Score = 34.3 bits (77), Expect = 0.30
Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 20/133 (15%)
Query: 352 TLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADG 411
T LF++R + + A F+ D++ H+ T + + FG + D+ + + G
Sbjct: 492 TYLTNSLFDYRSPENNGTRAEFILDSTHHKETYTEIAGMQRFGAFYMDYLYTMENTSGKG 551
Query: 412 ---DRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETA-RRIQ 467
+D KS DL + TK+ GP DF +A RI
Sbjct: 552 STNQQDFSSGKSEDLGTVQEKSTKSL----------------VIGPLDFRLDSSAVHRIL 595
Query: 468 DLIPVLLRHRLCP 480
+I L H P
Sbjct: 596 KMIVCALEHEYEP 608
>gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens]
Length = 3997
Score = 34.3 bits (77), Expect = 0.30
Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 20/133 (15%)
Query: 352 TLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADG 411
T LF++R + + A F+ D++ H+ T + + FG + D+ + + G
Sbjct: 492 TYLTNSLFDYRSPENNGTRAEFILDSTHHKETYTEIAGMQRFGAFYMDYLYTMENTSGKG 551
Query: 412 ---DRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETA-RRIQ 467
+D KS DL + TK+ GP DF +A RI
Sbjct: 552 STNQQDFSSGKSEDLGTVQEKSTKSL----------------VIGPLDFRLDSSAVHRIL 595
Query: 468 DLIPVLLRHRLCP 480
+I L H P
Sbjct: 596 KMIVCALEHEYEP 608
>gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens]
Length = 863
Score = 34.3 bits (77), Expect = 0.30
Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 20/133 (15%)
Query: 352 TLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADG 411
T LF++R + + A F+ D++ H+ T + + FG + D+ + + G
Sbjct: 492 TYLTNSLFDYRSPENNGTRAEFILDSTHHKETYTEIAGMQRFGAFYMDYLYTMENTSGKG 551
Query: 412 ---DRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETA-RRIQ 467
+D KS DL + TK+ GP DF +A RI
Sbjct: 552 STNQQDFSSGKSEDLGTVQEKSTKSL----------------VIGPLDFRLDSSAVHRIL 595
Query: 468 DLIPVLLRHRLCP 480
+I L H P
Sbjct: 596 KMIVCALEHEYEP 608
>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 32.0 bits (71), Expect = 1.5
Identities = 22/60 (36%), Positives = 25/60 (41%), Gaps = 11/60 (18%)
Query: 11 GTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKT 70
G+ Q +T W L P RWGPC G G GRG G RR RE +T
Sbjct: 404 GSAIQALETSAW---VLPPSTGRWGPCRGC--------GRGRGRGRGRGRRPRELGTEET 452
>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 32.0 bits (71), Expect = 1.5
Identities = 22/60 (36%), Positives = 25/60 (41%), Gaps = 11/60 (18%)
Query: 11 GTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKT 70
G+ Q +T W L P RWGPC G G GRG G RR RE +T
Sbjct: 404 GSAIQALETSAW---VLPPSTGRWGPCRGC--------GRGRGRGRGRGRRPRELGTEET 452
>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 32.0 bits (71), Expect = 1.5
Identities = 22/60 (36%), Positives = 25/60 (41%), Gaps = 11/60 (18%)
Query: 11 GTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKT 70
G+ Q +T W L P RWGPC G G GRG G RR RE +T
Sbjct: 404 GSAIQALETSAW---VLPPSTGRWGPCRGC--------GRGRGRGRGRGRRPRELGTEET 452
>gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo
sapiens]
Length = 647
Score = 31.6 bits (70), Expect = 1.9
Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 27/101 (26%)
Query: 7 GLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKF-------YQDGPGR---GLGE 56
GL RGT Q T W AL P GG+W +F +QDG R G G
Sbjct: 317 GLARGTAPQPAST--W---ALAARPR----AGGTWTSRFEAQRGCAHQDGQRRTRDGAGN 367
Query: 57 EDIRRAR-------EARPRKTPRPQLSDRSRERKVPASRIS 90
AR RPR+ PR L + + R+ P +R S
Sbjct: 368 HASEPARVWSPPPRRQRPRRLPRASLQEEPK-RRPPCARPS 407
>gi|239748099 PREDICTED: hypothetical protein [Homo sapiens]
Length = 295
Score = 31.6 bits (70), Expect = 1.9
Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 19/131 (14%)
Query: 13 GGQLGQTVGWPCGALGPGPH-------RWGPCGGSWAQKFY----QDGPGRGLGEEDIRR 61
G +L T WP G L GP R GG A++ + G R L E R
Sbjct: 85 GARLQATRTWPAGILEGGPQVAARGGGRGWEGGGLGARRAVTAARRGGASRPLAGEPWRE 144
Query: 62 AREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRLQ 121
A RP++ P+ R+RE + A R++N G+ A+ GR +
Sbjct: 145 AARRRPQQCPQ---WGRARESRSAALASPRVSNAPTTPASRNPGLRAQ----ERQSGR-R 196
Query: 122 SEGGSGLDSSP 132
+ GG G + P
Sbjct: 197 AAGGGGARAEP 207
>gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo
sapiens]
Length = 647
Score = 31.6 bits (70), Expect = 1.9
Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 27/101 (26%)
Query: 7 GLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKF-------YQDGPGR---GLGE 56
GL RGT Q T W AL P GG+W +F +QDG R G G
Sbjct: 317 GLARGTAPQPAST--W---ALAARPR----AGGTWTSRFEAQRGCAHQDGQRRTRDGAGN 367
Query: 57 EDIRRAR-------EARPRKTPRPQLSDRSRERKVPASRIS 90
AR RPR+ PR L + + R+ P +R S
Sbjct: 368 HASEPARVWSPPPRRQRPRRLPRASLQEEPK-RRPPCARPS 407
>gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens]
Length = 676
Score = 31.2 bits (69), Expect = 2.5
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Query: 44 KFYQDGPGRGLGEED--IRRAREARPRKTPRPQLSDRSRERK 83
KF Q PGRG G +D +R + + R P S R R+RK
Sbjct: 550 KFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRK 591
>gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens]
Length = 678
Score = 31.2 bits (69), Expect = 2.5
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Query: 44 KFYQDGPGRGLGEED--IRRAREARPRKTPRPQLSDRSRERK 83
KF Q PGRG G +D +R + + R P S R R+RK
Sbjct: 552 KFLQSYPGRGSGSDDTELRYSSQYEERLDPFSSFSKRERQRK 593
>gi|32528297 ribosomal protein S6 kinase, polypeptide 5 isoform b
[Homo sapiens]
Length = 549
Score = 31.2 bits (69), Expect = 2.5
Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Query: 345 QICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTD 399
QI + L L L + + D N L D++ H V L DFG S+EF + T+
Sbjct: 155 QIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGH-VVLTDFGLSKEFVADETE 208
>gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a
[Homo sapiens]
Length = 802
Score = 31.2 bits (69), Expect = 2.5
Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Query: 345 QICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTD 399
QI + L L L + + D N L D++ H V L DFG S+EF + T+
Sbjct: 155 QIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGH-VVLTDFGLSKEFVADETE 208
>gi|55743138 ribosomal protein S6 kinase, 90kDa, polypeptide 4
isoform b [Homo sapiens]
Length = 766
Score = 30.8 bits (68), Expect = 3.3
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 351 LTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTE 396
+ L L L + + D N L D+ H + L DFG S+EF TE
Sbjct: 145 IVLALEHLHKLGIIYRDLKLENVLLDSEGH-IVLTDFGLSKEFLTE 189
>gi|4506735 ribosomal protein S6 kinase, 90kDa, polypeptide 4
isoform a [Homo sapiens]
Length = 772
Score = 30.8 bits (68), Expect = 3.3
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 351 LTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTE 396
+ L L L + + D N L D+ H + L DFG S+EF TE
Sbjct: 145 IVLALEHLHKLGIIYRDLKLENVLLDSEGH-IVLTDFGLSKEFLTE 189
>gi|197313667 cell division cycle 7 [Homo sapiens]
Length = 574
Score = 30.0 bits (66), Expect = 5.7
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 11/88 (12%)
Query: 341 DLRNQICFQ-----LLTL--CLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREF 393
D+ N + FQ +L L L+ + +F + D +NFLY+ + L+DFG ++
Sbjct: 144 DILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQ-- 201
Query: 394 GTEFTD-HYIEVVKAAADGDRDCVLQKS 420
GT T ++ V++ A +R C KS
Sbjct: 202 GTHDTKIELLKFVQSEAQQER-CSQNKS 228
>gi|197313665 cell division cycle 7 [Homo sapiens]
Length = 574
Score = 30.0 bits (66), Expect = 5.7
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 11/88 (12%)
Query: 341 DLRNQICFQ-----LLTL--CLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREF 393
D+ N + FQ +L L L+ + +F + D +NFLY+ + L+DFG ++
Sbjct: 144 DILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQ-- 201
Query: 394 GTEFTD-HYIEVVKAAADGDRDCVLQKS 420
GT T ++ V++ A +R C KS
Sbjct: 202 GTHDTKIELLKFVQSEAQQER-CSQNKS 228
>gi|4502715 cell division cycle 7 [Homo sapiens]
Length = 574
Score = 30.0 bits (66), Expect = 5.7
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 11/88 (12%)
Query: 341 DLRNQICFQ-----LLTL--CLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREF 393
D+ N + FQ +L L L+ + +F + D +NFLY+ + L+DFG ++
Sbjct: 144 DILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQ-- 201
Query: 394 GTEFTD-HYIEVVKAAADGDRDCVLQKS 420
GT T ++ V++ A +R C KS
Sbjct: 202 GTHDTKIELLKFVQSEAQQER-CSQNKS 228
>gi|41393599 coproporphyrinogen oxidase [Homo sapiens]
Length = 454
Score = 29.6 bits (65), Expect = 7.4
Identities = 49/192 (25%), Positives = 77/192 (40%), Gaps = 43/192 (22%)
Query: 15 QLGQTVGWPC-----GALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRK 69
QLG+ PC G G GP W CGG + + Q R+ R +
Sbjct: 4 QLGRLSSGPCWLVARGGCG-GPRAWSQCGGGGLRAWSQ-------------RSAAGRVCR 49
Query: 70 TPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRLQSEGGSGLD 129
P P +++S R + SR GG VG GL A +A G GL
Sbjct: 50 PPGPAGTEQS--RGLGHGSTSR----GGPWVGTGLA--AALA------------GLVGLA 89
Query: 130 SSPFLSEANAERIVQ---TLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVRQSADFM 186
++ F AE + + T T G + L+ + +SF++P + + E R+ D
Sbjct: 90 TAAFGHVQRAEMLPKTSGTRATSLGRPEEEEDELAHRCSSFMAPPVTDLGELRRRPGDMK 149
Query: 187 PRWQMLRVLEEE 198
+ ++L +LE +
Sbjct: 150 TKMELL-ILETQ 160
>gi|89111943 Kruppel-like factor 8 isoform 1 [Homo sapiens]
Length = 359
Score = 29.3 bits (64), Expect = 9.6
Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 8/101 (7%)
Query: 190 QMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPG----IAQ 245
Q+L V+ K+ L+ +P S+ V+ L DG A+ + G A
Sbjct: 155 QILHVIHTIPSVSLPNKMGGLKTIPVVVQSLPMVYTTLPADGGPAAITVPLIGGDGKNAG 214
Query: 246 SIQSDVQNLLAVLKMS----AALPAGLFAEQSLQALQQELA 282
S++ D ++ + S + + +G A QSLQ LQQE A
Sbjct: 215 SVKVDPTSMSPLEIPSDSEESTIESGSSALQSLQGLQQEPA 255
>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
Length = 2186
Score = 29.3 bits (64), Expect = 9.6
Identities = 15/45 (33%), Positives = 23/45 (51%)
Query: 124 GGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFI 168
GG+G+ S +L + N V TVR + Q+ + DNS+I
Sbjct: 178 GGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYI 222
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,256,503
Number of Sequences: 37866
Number of extensions: 1059122
Number of successful extensions: 2833
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 2811
Number of HSP's gapped (non-prelim): 36
length of query: 544
length of database: 18,247,518
effective HSP length: 107
effective length of query: 437
effective length of database: 14,195,856
effective search space: 6203589072
effective search space used: 6203589072
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.