Guide to the Human Genome
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Search of human proteins with 26667230

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|26667230 eyes absent 2 isoform c [Homo sapiens]
         (514 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|26667230 eyes absent 2 isoform c [Homo sapiens]                   1055   0.0  
gi|26667227 eyes absent 2 isoform a [Homo sapiens]                   1042   0.0  
gi|26667240 eyes absent 2 isoform b [Homo sapiens]                   1042   0.0  
gi|26667235 eyes absent 2 isoform a [Homo sapiens]                   1042   0.0  
gi|26667232 eyes absent 2 isoform a [Homo sapiens]                   1042   0.0  
gi|19923100 eyes absent 1 isoform b [Homo sapiens]                    644   0.0  
gi|26667216 eyes absent 1 isoform b [Homo sapiens]                    644   0.0  
gi|26667222 eyes absent 1 isoform a [Homo sapiens]                    644   0.0  
gi|26667219 eyes absent 1 isoform c [Homo sapiens]                    581   e-166
gi|98991763 eyes absent 4 isoform b [Homo sapiens]                    576   e-164
gi|98991760 eyes absent 4 isoform a [Homo sapiens]                    576   e-164
gi|26667257 eyes absent 4 isoform d [Homo sapiens]                    557   e-159
gi|26667243 eyes absent 3 [Homo sapiens]                              444   e-125
gi|57165375 glutamate receptor, ionotropic, N-methyl D-aspartate...    48   2e-05
gi|57165373 glutamate receptor, ionotropic, N-methyl D-aspartate...    48   2e-05
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s...    43   6e-04
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...    43   6e-04
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap...    43   6e-04
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s...    42   0.001
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    39   0.009
gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens]          39   0.015
gi|24497526 homeobox B1 [Homo sapiens]                                 38   0.025
gi|41281683 disabled homolog 2 interacting protein isoform 2 [Ho...    37   0.056
gi|94967023 disabled homolog 2 interacting protein isoform 1 [Ho...    37   0.056
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     37   0.056
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     37   0.056
gi|19923391 homeobox D3 [Homo sapiens]                                 36   0.073
gi|56117846 synovial sarcoma translocation, chromosome 18 isofor...    36   0.073
gi|56117844 synovial sarcoma translocation, chromosome 18 isofor...    36   0.073
gi|14149669 mitogen-activated protein kinase kinase kinase 7 int...    36   0.096

>gi|26667230 eyes absent 2 isoform c [Homo sapiens]
          Length = 514

 Score = 1055 bits (2729), Expect = 0.0
 Identities = 514/514 (100%), Positives = 514/514 (100%)

Query: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
           MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60

Query: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMHGTTGFY 120
           QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMHGTTGFY
Sbjct: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMHGTTGFY 120

Query: 121 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVL 180
           QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVL
Sbjct: 121 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVL 180

Query: 181 QEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGD 240
           QEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGD
Sbjct: 181 QEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGD 240

Query: 241 NEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFND 300
           NEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFND
Sbjct: 241 NEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFND 300

Query: 301 LEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRY 360
           LEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRY
Sbjct: 301 LEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRY 360

Query: 361 RRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNV 420
           RRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNV
Sbjct: 361 RRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNV 420

Query: 421 LVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGV 480
           LVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGV
Sbjct: 421 LVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGV 480

Query: 481 EEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514
           EEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 481 EEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514


>gi|26667227 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 514/538 (95%), Positives = 514/538 (95%), Gaps = 24/538 (4%)

Query: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
           MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60

Query: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS---------------------- 98
           QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS                      
Sbjct: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120

Query: 99  --FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 156
             FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180

Query: 157 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 216
           SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240

Query: 217 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 276
           PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300

Query: 277 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 336
           SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360

Query: 337 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 396
           GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420

Query: 397 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 456
           TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480

Query: 457 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514
           ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|26667240 eyes absent 2 isoform b [Homo sapiens]
          Length = 543

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 514/538 (95%), Positives = 514/538 (95%), Gaps = 24/538 (4%)

Query: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
           MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 6   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 65

Query: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS---------------------- 98
           QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS                      
Sbjct: 66  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 125

Query: 99  --FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 156
             FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 126 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 185

Query: 157 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 216
           SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 186 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 245

Query: 217 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 276
           PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 246 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 305

Query: 277 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 336
           SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 306 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 365

Query: 337 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 396
           GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 366 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 425

Query: 397 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 456
           TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 426 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 485

Query: 457 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514
           ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 486 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 543


>gi|26667235 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 514/538 (95%), Positives = 514/538 (95%), Gaps = 24/538 (4%)

Query: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
           MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60

Query: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS---------------------- 98
           QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS                      
Sbjct: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120

Query: 99  --FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 156
             FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180

Query: 157 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 216
           SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240

Query: 217 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 276
           PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300

Query: 277 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 336
           SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360

Query: 337 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 396
           GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420

Query: 397 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 456
           TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480

Query: 457 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514
           ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|26667232 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 514/538 (95%), Positives = 514/538 (95%), Gaps = 24/538 (4%)

Query: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
           MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60

Query: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS---------------------- 98
           QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS                      
Sbjct: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120

Query: 99  --FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 156
             FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180

Query: 157 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 216
           SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240

Query: 217 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 276
           PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300

Query: 277 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 336
           SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360

Query: 337 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 396
           GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420

Query: 397 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 456
           TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480

Query: 457 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514
           ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|19923100 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score =  644 bits (1661), Expect = 0.0
 Identities = 323/502 (64%), Positives = 376/502 (74%), Gaps = 38/502 (7%)

Query: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS------------ 98
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI S            
Sbjct: 91  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 150

Query: 99  -------------------FSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 134
                              FST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 151 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 210

Query: 135 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 192
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 211 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 270

Query: 193 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 252
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 271 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 330

Query: 253 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 312
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 331 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 390

Query: 313 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 372
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 391 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 450

Query: 373 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 432
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 451 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 510

Query: 433 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 492
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 511 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 570

Query: 493 FWRISCHADLEALRHALELEYL 514
           FWRIS H+DL AL HALELEYL
Sbjct: 571 FWRISSHSDLMALHHALELEYL 592


>gi|26667216 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score =  644 bits (1661), Expect = 0.0
 Identities = 323/502 (64%), Positives = 376/502 (74%), Gaps = 38/502 (7%)

Query: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS------------ 98
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI S            
Sbjct: 91  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 150

Query: 99  -------------------FSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 134
                              FST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 151 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 210

Query: 135 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 192
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 211 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 270

Query: 193 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 252
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 271 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 330

Query: 253 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 312
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 331 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 390

Query: 313 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 372
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 391 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 450

Query: 373 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 432
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 451 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 510

Query: 433 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 492
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 511 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 570

Query: 493 FWRISCHADLEALRHALELEYL 514
           FWRIS H+DL AL HALELEYL
Sbjct: 571 FWRISSHSDLMALHHALELEYL 592


>gi|26667222 eyes absent 1 isoform a [Homo sapiens]
          Length = 559

 Score =  644 bits (1661), Expect = 0.0
 Identities = 323/502 (64%), Positives = 376/502 (74%), Gaps = 38/502 (7%)

Query: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS------------ 98
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI S            
Sbjct: 58  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 117

Query: 99  -------------------FSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 134
                              FST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 118 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 177

Query: 135 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 192
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 178 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 237

Query: 193 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 252
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 238 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 297

Query: 253 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 312
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 298 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 357

Query: 313 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 372
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 358 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 417

Query: 373 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 432
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 418 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 477

Query: 433 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 492
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 478 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 537

Query: 493 FWRISCHADLEALRHALELEYL 514
           FWRIS H+DL AL HALELEYL
Sbjct: 538 FWRISSHSDLMALHHALELEYL 559


>gi|26667219 eyes absent 1 isoform c [Homo sapiens]
          Length = 557

 Score =  581 bits (1498), Expect = e-166
 Identities = 298/497 (59%), Positives = 350/497 (70%), Gaps = 63/497 (12%)

Query: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS------------ 98
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI S            
Sbjct: 91  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGIKTEGGLSQS 150

Query: 99  --------------FSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGSVHQDY 139
                         FST   GQ+PY+YQM G++     G Y G N L N++GF S  QDY
Sbjct: 151 QSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDY 210

Query: 140 PSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSSESLAG 197
           PSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+      
Sbjct: 211 PSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTA 270

Query: 198 EYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIII 257
           EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLDETII+
Sbjct: 271 EYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIV 330

Query: 258 FHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDN 317
           FHSLLTG++A+RYG+                              +CDQ+H+DDVSSDDN
Sbjct: 331 FHSLLTGSYANRYGR------------------------------ECDQVHIDDVSSDDN 360

Query: 318 GQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGL 377
           GQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKNNVGGL
Sbjct: 361 GQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGL 420

Query: 378 IGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLY 437
           +G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALAKVLLY
Sbjct: 421 LGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLY 480

Query: 438 GLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRIS 497
           GLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MPFWRIS
Sbjct: 481 GLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRIS 540

Query: 498 CHADLEALRHALELEYL 514
            H+DL AL HALELEYL
Sbjct: 541 SHSDLMALHHALELEYL 557


>gi|98991763 eyes absent 4 isoform b [Homo sapiens]
          Length = 616

 Score =  576 bits (1485), Expect = e-164
 Identities = 304/515 (59%), Positives = 365/515 (70%), Gaps = 48/515 (9%)

Query: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 110 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 168

Query: 98  S---------------------------------FSTSPTGQSPYTYQMHGTT----GFY 120
           +                                 FST   GQ+PY+YQM G++       
Sbjct: 169 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 228

Query: 121 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 179
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 229 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 288

Query: 180 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 239
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 289 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 341

Query: 240 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 299
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 342 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 401

Query: 300 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 359
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 402 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 461

Query: 360 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 419
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 462 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 521

Query: 420 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 479
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 522 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 581

Query: 480 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 582 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616


>gi|98991760 eyes absent 4 isoform a [Homo sapiens]
          Length = 639

 Score =  576 bits (1485), Expect = e-164
 Identities = 304/515 (59%), Positives = 365/515 (70%), Gaps = 48/515 (9%)

Query: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 133 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 191

Query: 98  S---------------------------------FSTSPTGQSPYTYQMHGTT----GFY 120
           +                                 FST   GQ+PY+YQM G++       
Sbjct: 192 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 251

Query: 121 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 179
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 252 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 311

Query: 180 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 239
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 312 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 364

Query: 240 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 299
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 365 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 424

Query: 300 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 359
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 425 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 484

Query: 360 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 419
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 485 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 544

Query: 420 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 479
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 545 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 604

Query: 480 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 605 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639


>gi|26667257 eyes absent 4 isoform d [Homo sapiens]
          Length = 639

 Score =  557 bits (1436), Expect = e-159
 Identities = 294/515 (57%), Positives = 358/515 (69%), Gaps = 48/515 (9%)

Query: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 133 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 191

Query: 98  S---------------------------------FSTSPTGQSPYTYQMHGTT----GFY 120
           +                                 FST   GQ+PY+YQM G++       
Sbjct: 192 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 251

Query: 121 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 179
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 252 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 311

Query: 180 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 239
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 312 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 364

Query: 240 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 299
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 365 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 424

Query: 300 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 359
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 425 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 484

Query: 360 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 419
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 485 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 544

Query: 420 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 479
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERI+ RFG    YVVIGDG
Sbjct: 545 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDG 604

Query: 480 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514
            +EE  A +HNMPFWRIS H+DL AL  ALELEYL
Sbjct: 605 RDEEHAANQHNMPFWRISSHSDLLALHQALELEYL 639


>gi|26667243 eyes absent 3 [Homo sapiens]
          Length = 573

 Score =  444 bits (1142), Expect = e-125
 Identities = 248/516 (48%), Positives = 321/516 (62%), Gaps = 41/516 (7%)

Query: 38  ITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIP 97
           I +S+    SQ++S      +   P +  A  GQTQY   +QQ  PY  YP   Q YG+P
Sbjct: 60  IPRSSNDYTSQMYSAKPYAHILSVPVSETAYPGQTQYQT-LQQTQPYAVYPQATQTYGLP 118

Query: 98  SFSTSPTGQSP-------------------------------YTYQMHGTT---GFYQGG 123
            F     G  P                               Y+Y +  ++         
Sbjct: 119 PFGALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQASSTNASLISTS 178

Query: 124 NGLGN--AAGFGSV-HQDYPSYPGFPQSQYPQYY-GSSYNPPYVPASSICPSPLSTSTYV 179
           + + N  AA   S+ +QDYP+Y    Q+QY   Y  SS+       S    + L+ +TY 
Sbjct: 179 STIANIPAAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSDAESTTLAATTYQ 238

Query: 180 LQEASHNVPNQSSESLA-GEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPA 238
            ++ S   P  +++ L+ G+ +T    S      DTD   R +    + R KR +D + +
Sbjct: 239 SEKPSVMAPAPAAQRLSSGDPSTSPSLSQTTPSKDTDDQSRKNMTS-KNRGKRKADATSS 297

Query: 239 GDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFF 298
            D+E+ERVF+WDLDETIIIFHSLLTG++A +YGKD T  +  GL MEEMIF +ADTHLFF
Sbjct: 298 QDSELERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFF 357

Query: 299 NDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAF 358
           NDLE+CDQ+HV+DV+SDDNGQDLS Y+FS DGF  S    +     GV GGVDWMRKLAF
Sbjct: 358 NDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAF 417

Query: 359 RYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCV 418
           RYR+V+E+Y+ +K+NVGGL+   ++E   +LRAE+E LTD WL  +LK+L LI SR NCV
Sbjct: 418 RYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCV 477

Query: 419 NVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGD 478
           NVL+TTTQL+PALAKVLLYGLG +FPIENIYSATK GKESCFERI+ RFG+K  YVVIGD
Sbjct: 478 NVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGD 537

Query: 479 GVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514
           G +EE  AK+HNMPFWRI+ H DL +L  ALEL++L
Sbjct: 538 GRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL 573


>gi|57165375 glutamate receptor, ionotropic, N-methyl
           D-aspartate-associated protein 1 [Homo sapiens]
          Length = 371

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 38/100 (38%), Positives = 42/100 (42%), Gaps = 8/100 (8%)

Query: 74  YSAGIQQATPYTAYPP-PAQAYGIPSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGF 132
           Y  G Q   P  A PP P   Y  P F  SP GQ  Y    HG + + QGG   G     
Sbjct: 21  YPGGPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYP---HGPSPYPQGGYPQGPYPQG 77

Query: 133 GSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSP 172
           G     YP   G+PQ  YPQ  G     PY P S   P+P
Sbjct: 78  GYPQGPYPQ-EGYPQGPYPQ--GGYPQGPY-PQSPFPPNP 113


>gi|57165373 glutamate receptor, ionotropic, N-methyl
           D-aspartate-associated protein 1 [Homo sapiens]
          Length = 371

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 38/100 (38%), Positives = 42/100 (42%), Gaps = 8/100 (8%)

Query: 74  YSAGIQQATPYTAYPP-PAQAYGIPSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGF 132
           Y  G Q   P  A PP P   Y  P F  SP GQ  Y    HG + + QGG   G     
Sbjct: 21  YPGGPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYP---HGPSPYPQGGYPQGPYPQG 77

Query: 133 GSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSP 172
           G     YP   G+PQ  YPQ  G     PY P S   P+P
Sbjct: 78  GYPQGPYPQ-EGYPQGPYPQ--GGYPQGPY-PQSPFPPNP 113


>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
           sapiens]
          Length = 354

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 50/162 (30%), Positives = 66/162 (40%), Gaps = 22/162 (13%)

Query: 67  AAYGQTQYSAGI-QQATPYT------AYPPPAQAYGIPSFSTSP----TGQSPYTYQM-H 114
           A YGQT Y+    Q  T YT      AY  P Q YG  ++ T+     T Q+ Y  Q  +
Sbjct: 59  ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 115 GTTGFYQGGNGLGNAAGFGSVHQD--YPSYPGFPQSQYPQY------YG-SSYNPPYVPA 165
           GT   Y    G   AA   +  QD   P+    PQS    Y      YG S+Y+ P VP 
Sbjct: 119 GTQPAYPA-YGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG 177

Query: 166 SSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPST 207
           S       +  +Y     S   P    +S   + NT+  PS+
Sbjct: 178 SYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSS 219



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 46/179 (25%), Positives = 59/179 (32%), Gaps = 42/179 (23%)

Query: 55  PRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMH 114
           P   P QP TA  +Y  T YS                        ST PT     +Y   
Sbjct: 176 PGSYPMQPVTAPPSYPPTSYS------------------------STQPTSYDQSSYSQQ 211

Query: 115 GTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLS 174
            T   Y   +  G  + +G             QS Y Q   +SY PP   + S  PS  S
Sbjct: 212 NT---YGQPSSYGQQSSYGQ------------QSSYGQQPPTSY-PPQTGSYSQAPSQYS 255

Query: 175 -TSTYVLQEASHNVPNQSSESLAG-EYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKR 231
             S+   Q++S    + SS  + G E    +GP         D   R   G  RG   R
Sbjct: 256 QQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR 314


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
           sapiens]
          Length = 655

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 50/162 (30%), Positives = 66/162 (40%), Gaps = 22/162 (13%)

Query: 67  AAYGQTQYSAGI-QQATPYT------AYPPPAQAYGIPSFSTSP----TGQSPYTYQM-H 114
           A YGQT Y+    Q  T YT      AY  P Q YG  ++ T+     T Q+ Y  Q  +
Sbjct: 59  ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 115 GTTGFYQGGNGLGNAAGFGSVHQD--YPSYPGFPQSQYPQY------YG-SSYNPPYVPA 165
           GT   Y    G   AA   +  QD   P+    PQS    Y      YG S+Y+ P VP 
Sbjct: 119 GTQPAYPA-YGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG 177

Query: 166 SSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPST 207
           S       +  +Y     S   P    +S   + NT+  PS+
Sbjct: 178 SYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSS 219



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 46/179 (25%), Positives = 59/179 (32%), Gaps = 42/179 (23%)

Query: 55  PRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMH 114
           P   P QP TA  +Y  T YS                        ST PT     +Y   
Sbjct: 176 PGSYPMQPVTAPPSYPPTSYS------------------------STQPTSYDQSSYSQQ 211

Query: 115 GTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLS 174
            T   Y   +  G  + +G             QS Y Q   +SY PP   + S  PS  S
Sbjct: 212 NT---YGQPSSYGQQSSYGQ------------QSSYGQQPPTSY-PPQTGSYSQAPSQYS 255

Query: 175 -TSTYVLQEASHNVPNQSSESLAG-EYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKR 231
             S+   Q++S    + SS  + G E    +GP         D   R   G  RG   R
Sbjct: 256 QQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR 314


>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
           sapiens]
          Length = 656

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 50/162 (30%), Positives = 66/162 (40%), Gaps = 22/162 (13%)

Query: 67  AAYGQTQYSAGI-QQATPYT------AYPPPAQAYGIPSFSTSP----TGQSPYTYQM-H 114
           A YGQT Y+    Q  T YT      AY  P Q YG  ++ T+     T Q+ Y  Q  +
Sbjct: 59  ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 115 GTTGFYQGGNGLGNAAGFGSVHQD--YPSYPGFPQSQYPQY------YG-SSYNPPYVPA 165
           GT   Y    G   AA   +  QD   P+    PQS    Y      YG S+Y+ P VP 
Sbjct: 119 GTQPAYPA-YGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG 177

Query: 166 SSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPST 207
           S       +  +Y     S   P    +S   + NT+  PS+
Sbjct: 178 SYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSS 219



 Score = 32.7 bits (73), Expect = 0.81
 Identities = 51/200 (25%), Positives = 68/200 (34%), Gaps = 52/200 (26%)

Query: 55  PRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMH 114
           P   P QP TA  +Y  T YS                        ST PT     +Y   
Sbjct: 176 PGSYPMQPVTAPPSYPPTSYS------------------------STQPTSYDQSSYSQQ 211

Query: 115 GTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLS 174
            T   Y   +  G  + +G             QS Y Q   +SY PP   + S  PS  S
Sbjct: 212 NT---YGQPSSYGQQSSYGQ------------QSSYGQQPPTSY-PPQTGSYSQAPSQYS 255

Query: 175 --TSTYVLQE-------ASHNVPNQSSESLA--GEYNTHNGPSTPAK-EGDTDRPHRASD 222
             +S+Y  Q        +S  V  Q S   +  GE  + +GP    +  G  DR   +  
Sbjct: 256 QQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRG 315

Query: 223 GKLRGRSKRSSDPSPAGDNE 242
           G+  GR    S     G N+
Sbjct: 316 GRGGGRGGMGSAGERGGFNK 335


>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
           sapiens]
          Length = 600

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 59/224 (26%), Positives = 78/224 (34%), Gaps = 51/224 (22%)

Query: 67  AAYGQTQYSAGI-QQATPYT------AYPPPAQAYG------------------------ 95
           A YGQT Y+    Q  T YT      AY  P Q YG                        
Sbjct: 59  ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 96  -----IPSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQY 150
                 P++   P   +P +Y     T + Q      N  G  S +    SY    QS Y
Sbjct: 119 GTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYG--QQSSY 176

Query: 151 PQYYGSSYNPPYVPASSICPSPLS--TSTYVLQE-------ASHNVPNQSSESLA--GEY 199
            Q   +SY PP   + S  PS  S  +S+Y  Q        +S  V  Q S   +  GE 
Sbjct: 177 GQQPPTSY-PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGEN 235

Query: 200 NTHNGPSTPAK-EGDTDRPHRASDGKLRGRSKRSSDPSPAGDNE 242
            + +GP    +  G  DR   +  G+  GR    S     G N+
Sbjct: 236 RSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNK 279


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 44/146 (30%), Positives = 58/146 (39%), Gaps = 22/146 (15%)

Query: 69  YGQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYT-YQMHGTTGFYQGGNGLG 127
           YGQ  YS G  Q+T           YG  S+S+   GQS  T Y    T   Y    G G
Sbjct: 33  YGQQSYS-GYSQSTD-------TSGYGQSSYSSY--GQSQNTGYGTQSTPQGYGSTGGYG 82

Query: 128 NAAGFGSVHQDYPSYPGFPQSQYPQ----YYG-----SSYNPPYVPASSICPSPLSTSTY 178
           ++    S +    SYPG+ Q   P      YG     SSY  P   + S  PS       
Sbjct: 83  SSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQS 142

Query: 179 VLQEASHNVPNQSSESLAGEYNTHNG 204
             Q+ S+N P    +    +YN+ +G
Sbjct: 143 YGQQQSYNPPQGYGQQ--NQYNSSSG 166



 Score = 37.4 bits (85), Expect = 0.033
 Identities = 39/113 (34%), Positives = 48/113 (42%), Gaps = 18/113 (15%)

Query: 63  STAMAAYGQTQYSA-GIQQATPYTAYPPPAQAYG-IPSFSTSPTGQSPYTYQMHGTTGFY 120
           ST  + YGQ+ YS+ G  Q T Y     P Q YG    + +S + QS Y  Q     G+ 
Sbjct: 44  STDTSGYGQSSYSSYGQSQNTGYGTQSTP-QGYGSTGGYGSSQSSQSSYG-QQSSYPGYG 101

Query: 121 QGGNGLGNAAGFGSVHQDYPSYPGFPQ----SQYPQYYG--------SSYNPP 161
           Q       +  +GS  Q   S  G PQ    SQ P Y G         SYNPP
Sbjct: 102 QQPAPSSTSGSYGSSSQS--SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPP 152


>gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens]
          Length = 407

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 29/80 (36%), Positives = 35/80 (43%), Gaps = 8/80 (10%)

Query: 81  ATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYP 140
           A P    PPP+QA   P  S  PT Q  + Y  +   G+ Q  +G G   GF    Q  P
Sbjct: 318 AAPLAFPPPPSQA--APDMSKPPTAQPDFPYGQY--AGYGQDLSGFGQ--GFSDPSQQPP 371

Query: 141 SY--PGFPQSQYPQYYGSSY 158
           SY  P  P S  P   GS +
Sbjct: 372 SYGGPSVPGSGGPPAGGSGF 391


>gi|24497526 homeobox B1 [Homo sapiens]
          Length = 301

 Score = 37.7 bits (86), Expect = 0.025
 Identities = 38/154 (24%), Positives = 63/154 (40%), Gaps = 28/154 (18%)

Query: 51  SRSCPRVLPRQPSTAMAAYG-QTQYSAGI-----QQATPYTAYPPPAQAYGIPSFSTSPT 104
           + S P   P   + A+ +Y  + +Y  G+     QQ + Y A  PP+   G+P  S++P+
Sbjct: 24  AHSAPTSFPPSSAQAVDSYASEGRYGGGLSSPAFQQNSGYPAQQPPS-TLGVPFPSSAPS 82

Query: 105 GQSPYTYQ-MHGTTGFYQGGNGLGNAAGF---------GSVHQDYPSYPGFPQSQYPQY- 153
           G +P      +G + +Y  G   G+   F         G +   Y +    P    PQ+ 
Sbjct: 83  GYAPAACSPSYGPSQYYPLGQSEGDGGYFHPSSYGAQLGGLSDGYGAGGAGPGPYPPQHP 142

Query: 154 -YGSSYNPPYVPA---------SSICPSPLSTST 177
            YG+     + PA          + CPS  +T T
Sbjct: 143 PYGNEQTASFAPAYADLLSEDKETPCPSEPNTPT 176


>gi|41281683 disabled homolog 2 interacting protein isoform 2 [Homo
           sapiens]
          Length = 1065

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 52/237 (21%), Positives = 79/237 (33%), Gaps = 46/237 (19%)

Query: 40  KSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSF 99
           ++ P+ ++ L +       P  P T+  A G+ Q  A +    P         A G+P  
Sbjct: 664 RATPVNLAGLATVRRAGQTPTTPGTSEGAPGRPQLLAPLSFQNPVYQ-----MAAGLP-- 716

Query: 100 STSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVH---QDYPSYPGF----------- 145
             SP G      + H +   +     L  AA  GS     ++    PG            
Sbjct: 717 -LSPRGLGDSGSEGHSSLSSHSNSEELAAAAKLGSFSTAAEELARRPGELARRQMSLTEK 775

Query: 146 -------------PQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSS 192
                        PQ +  Q       PP  P     P+ LST  Y         P  SS
Sbjct: 776 GGQPTVPRQNSAGPQRRIDQPPPPPPPPPPAPRGRTPPNLLSTLQY---------PRPSS 826

Query: 193 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVW 249
            +LA       GPST  ++  +    +    +L+ R+     PSP   N ++R   W
Sbjct: 827 GTLASASPDWVGPSTRLRQQSSSS--KGDSPELKPRAVHKQGPSPVSPNALDRTAAW 881


>gi|94967023 disabled homolog 2 interacting protein isoform 1 [Homo
           sapiens]
          Length = 1132

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 52/237 (21%), Positives = 79/237 (33%), Gaps = 46/237 (19%)

Query: 40  KSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSF 99
           ++ P+ ++ L +       P  P T+  A G+ Q  A +    P         A G+P  
Sbjct: 760 RATPVNLAGLATVRRAGQTPTTPGTSEGAPGRPQLLAPLSFQNPVYQ-----MAAGLP-- 812

Query: 100 STSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVH---QDYPSYPGF----------- 145
             SP G      + H +   +     L  AA  GS     ++    PG            
Sbjct: 813 -LSPRGLGDSGSEGHSSLSSHSNSEELAAAAKLGSFSTAAEELARRPGELARRQMSLTEK 871

Query: 146 -------------PQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSS 192
                        PQ +  Q       PP  P     P+ LST  Y         P  SS
Sbjct: 872 GGQPTVPRQNSAGPQRRIDQPPPPPPPPPPAPRGRTPPNLLSTLQY---------PRPSS 922

Query: 193 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVW 249
            +LA       GPST  ++  +    +    +L+ R+     PSP   N ++R   W
Sbjct: 923 GTLASASPDWVGPSTRLRQQSSSS--KGDSPELKPRAVHKQGPSPVSPNALDRTAAW 977


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 45/169 (26%), Positives = 61/169 (36%), Gaps = 26/169 (15%)

Query: 70  GQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYT----YQMHG---TTGFYQ- 121
           G +    G    +   A PPPA  +G P +  SP+  +       +Q HG   + G    
Sbjct: 126 GGSSDGVGAPPHSAAAALPPPAYGFGQP-YGRSPSAVAAAAAAVFHQQHGGQQSPGLAAL 184

Query: 122 ---GGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYY-GSSYNPPYVPASSICPSPLSTST 177
              GG GL   AG      D+    GFP  QY  YY   S  PP  PA ++      T  
Sbjct: 185 QSGGGGGLEPYAGPQQNSHDH----GFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240

Query: 178 YVLQEASHNVPNQSSESLAG---------EYNTHNGPSTPAKEGDTDRP 217
                A+ + P  SS + A           +    G    A  G T +P
Sbjct: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQP 289



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 35/124 (28%), Positives = 42/124 (33%), Gaps = 31/124 (25%)

Query: 69  YGQTQYSA-GIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMHGTTGFYQGGNGLG 127
           YGQ   S  G Q  TPY     P      P +S  P  Q+P+                  
Sbjct: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA----------------- 496

Query: 128 NAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNV 187
                       PSY   PQSQ PQ   S   PPY    S  P   S + Y  Q+++   
Sbjct: 497 -----------QPSYQQQPQSQPPQLQSS--QPPYSQQPSQPPHQQSPAPYPSQQSTTQQ 543

Query: 188 PNQS 191
             QS
Sbjct: 544 HPQS 547



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 24/135 (17%)

Query: 79  QQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQD 138
           QQ  PY+  PP    +  PS+   P  Q P   Q+  +   Y       +       HQ 
Sbjct: 480 QQQPPYSQQPPSQTPHAQPSYQQQPQSQPP---QLQSSQPPY-------SQQPSQPPHQQ 529

Query: 139 YPS-YPG-------FPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQ 190
            P+ YP         PQSQ P Y       PY       P+P + S    Q+A++  P Q
Sbjct: 530 SPAPYPSQQSTTQQHPQSQ-PPYSQPQAQSPYQQQQPQQPAPSTLS----QQAAYPQP-Q 583

Query: 191 SSESLAGEYNTHNGP 205
           S +S    Y+    P
Sbjct: 584 SQQSQQTAYSQQRFP 598



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 41/179 (22%), Positives = 57/179 (31%), Gaps = 24/179 (13%)

Query: 59  PRQPSTA----MAAYGQTQYSAGIQQATPYTAYPPP---------AQAYGIPSFSTSPTG 105
           P+QP+ +     AAY Q Q     Q A     +PPP         +QA   PS ++S  G
Sbjct: 565 PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGG 624

Query: 106 QSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPA 165
           Q      +          +G  +    G+   +    PG   S      G   NP     
Sbjct: 625 QEDMNLSLQSRPSSLPDLSGSIDDLPMGT---EGALSPGVSTSGISSSQGEQSNP----- 676

Query: 166 SSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGK 224
                SP S  T                S A    + +GP +PA       P R   G+
Sbjct: 677 ---AQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQ 732


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 45/169 (26%), Positives = 61/169 (36%), Gaps = 26/169 (15%)

Query: 70  GQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYT----YQMHG---TTGFYQ- 121
           G +    G    +   A PPPA  +G P +  SP+  +       +Q HG   + G    
Sbjct: 126 GGSSDGVGAPPHSAAAALPPPAYGFGQP-YGRSPSAVAAAAAAVFHQQHGGQQSPGLAAL 184

Query: 122 ---GGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYY-GSSYNPPYVPASSICPSPLSTST 177
              GG GL   AG      D+    GFP  QY  YY   S  PP  PA ++      T  
Sbjct: 185 QSGGGGGLEPYAGPQQNSHDH----GFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPG 240

Query: 178 YVLQEASHNVPNQSSESLAG---------EYNTHNGPSTPAKEGDTDRP 217
                A+ + P  SS + A           +    G    A  G T +P
Sbjct: 241 SGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQP 289



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 35/124 (28%), Positives = 42/124 (33%), Gaps = 31/124 (25%)

Query: 69  YGQTQYSA-GIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMHGTTGFYQGGNGLG 127
           YGQ   S  G Q  TPY     P      P +S  P  Q+P+                  
Sbjct: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA----------------- 496

Query: 128 NAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNV 187
                       PSY   PQSQ PQ   S   PPY    S  P   S + Y  Q+++   
Sbjct: 497 -----------QPSYQQQPQSQPPQLQSS--QPPYSQQPSQPPHQQSPAPYPSQQSTTQQ 543

Query: 188 PNQS 191
             QS
Sbjct: 544 HPQS 547



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 24/135 (17%)

Query: 79  QQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQD 138
           QQ  PY+  PP    +  PS+   P  Q P   Q+  +   Y       +       HQ 
Sbjct: 480 QQQPPYSQQPPSQTPHAQPSYQQQPQSQPP---QLQSSQPPY-------SQQPSQPPHQQ 529

Query: 139 YPS-YPG-------FPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQ 190
            P+ YP         PQSQ P Y       PY       P+P + S    Q+A++  P Q
Sbjct: 530 SPAPYPSQQSTTQQHPQSQ-PPYSQPQAQSPYQQQQPQQPAPSTLS----QQAAYPQP-Q 583

Query: 191 SSESLAGEYNTHNGP 205
           S +S    Y+    P
Sbjct: 584 SQQSQQTAYSQQRFP 598



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 41/179 (22%), Positives = 57/179 (31%), Gaps = 24/179 (13%)

Query: 59  PRQPSTA----MAAYGQTQYSAGIQQATPYTAYPPP---------AQAYGIPSFSTSPTG 105
           P+QP+ +     AAY Q Q     Q A     +PPP         +QA   PS ++S  G
Sbjct: 565 PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGG 624

Query: 106 QSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPA 165
           Q      +          +G  +    G+   +    PG   S      G   NP     
Sbjct: 625 QEDMNLSLQSRPSSLPDLSGSIDDLPMGT---EGALSPGVSTSGISSSQGEQSNP----- 676

Query: 166 SSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGK 224
                SP S  T                S A    + +GP +PA       P R   G+
Sbjct: 677 ---AQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQ 732


>gi|19923391 homeobox D3 [Homo sapiens]
          Length = 432

 Score = 36.2 bits (82), Expect = 0.073
 Identities = 44/168 (26%), Positives = 62/168 (36%), Gaps = 29/168 (17%)

Query: 69  YGQTQYSAGIQQATPYTAYPPPAQAYGI----PSFSTSPTGQSPYTYQMH---------- 114
           YG ++ +     +TP+  YPPPA A  +    P  + S    +P     H          
Sbjct: 32  YGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCM 91

Query: 115 -GTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNP-PYVPASSICPSP 172
              TG  QGG G     G  S  Q  P  P  P    P    S  NP   VPA      P
Sbjct: 92  RPGTGNSQGGGGGSQPPGLNSEQQ--PPQPPPPPPTLPP--SSPTNPGGGVPAKKPKGGP 147

Query: 173 LSTSTYV---------LQEASHNVPNQSSESLAGEYNTHNGPSTPAKE 211
            ++S+           ++E+  N   ++S + AGE      P  PA +
Sbjct: 148 NASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASK 195


>gi|56117846 synovial sarcoma translocation, chromosome 18 isoform 1
           [Homo sapiens]
          Length = 418

 Score = 36.2 bits (82), Expect = 0.073
 Identities = 33/95 (34%), Positives = 35/95 (36%), Gaps = 21/95 (22%)

Query: 70  GQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNA 129
           G +QY    QQ   Y   PPP Q Y  P       GQ  Y  Q  G  G  QGG G    
Sbjct: 325 GNSQYG---QQQDAYQG-PPPQQGY--PPQQQQYPGQQGYPGQQQGY-GPSQGGPG---- 373

Query: 130 AGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVP 164
                     P YP +PQ Q  QY G     P  P
Sbjct: 374 ----------PQYPNYPQGQGQQYGGYRPTQPGPP 398


>gi|56117844 synovial sarcoma translocation, chromosome 18 isoform 2
           [Homo sapiens]
          Length = 387

 Score = 36.2 bits (82), Expect = 0.073
 Identities = 33/95 (34%), Positives = 35/95 (36%), Gaps = 21/95 (22%)

Query: 70  GQTQYSAGIQQATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNA 129
           G +QY    QQ   Y   PPP Q Y  P       GQ  Y  Q  G  G  QGG G    
Sbjct: 294 GNSQYG---QQQDAYQG-PPPQQGY--PPQQQQYPGQQGYPGQQQGY-GPSQGGPG---- 342

Query: 130 AGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVP 164
                     P YP +PQ Q  QY G     P  P
Sbjct: 343 ----------PQYPNYPQGQGQQYGGYRPTQPGPP 367


>gi|14149669 mitogen-activated protein kinase kinase kinase 7
           interacting protein 2 [Homo sapiens]
          Length = 693

 Score = 35.8 bits (81), Expect = 0.096
 Identities = 56/238 (23%), Positives = 83/238 (34%), Gaps = 42/238 (17%)

Query: 29  VWTLSDRQGITKSAP-------LRVSQLFSRSCPRVLPRQPSTA--MAAYGQTQYSAGIQ 79
           V+ +S   G + SAP        + +   S+  PR  P   + A  +     T  S  I 
Sbjct: 139 VFGMSSSSGASNSAPHLGFHLGSKGTSSLSQQTPRFNPIMVTLAPNIQTGRNTPTSLHIH 198

Query: 80  QATPYTAYPPPAQAYGIPSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDY 139
              P     P   +  I  + T+P G +  T Q  G    +       N      V+Q  
Sbjct: 199 GVPPPVLNSPQGNSIYIRPYITTPGGTTRQTQQHSGWVSQF-------NPMNPQQVYQ-- 249

Query: 140 PSYPG------------FPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNV 187
           PS PG               SQ P   G   +  Y+P SS   S         Q  + + 
Sbjct: 250 PSQPGPWTTCPASNPLSHTSSQQPNQQGHQTSHVYMPISSPTTS---------QPPTIHS 300

Query: 188 PNQSSESLAGEYNTHNGPSTPAK---EGDTDRPHRASDGKLRGRSKRSSDPSPAGDNE 242
              S  S   +YN  N  + P K   E   + P R +  KLR    R+S  S + +++
Sbjct: 301 SGSSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNNSSKLRSSGPRTSSTSSSVNSQ 358


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,115,722
Number of Sequences: 37866
Number of extensions: 1033098
Number of successful extensions: 4091
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 138
Number of HSP's that attempted gapping in prelim test: 3816
Number of HSP's gapped (non-prelim): 347
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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