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Search of human proteins with 121114302
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|121114302 cullin 4B isoform 2 [Homo sapiens]
(895 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|121114302 cullin 4B isoform 2 [Homo sapiens] 1751 0.0
gi|121114298 cullin 4B isoform 1 [Homo sapiens] 1742 0.0
gi|57165424 cullin 4A isoform 1 [Homo sapiens] 1243 0.0
gi|11140811 cullin 4A isoform 2 [Homo sapiens] 1138 0.0
gi|4503165 cullin 3 [Homo sapiens] 503 e-142
gi|32307161 cullin 1 [Homo sapiens] 339 6e-93
gi|19482174 cullin 2 [Homo sapiens] 308 1e-83
gi|40254446 Vasopressin-activated calcium-mobilizing receptor-1 ... 238 1e-62
gi|7019327 anaphase-promoting complex subunit 2 [Homo sapiens] 63 1e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 52 2e-06
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 49 3e-05
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 48 5e-05
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 47 6e-05
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 45 4e-04
gi|161016767 mucin 21 [Homo sapiens] 44 7e-04
gi|40807452 peroxisome proliferator-activated receptor gamma, co... 42 0.002
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti... 42 0.003
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens] 42 0.003
gi|169213511 PREDICTED: hypothetical protein [Homo sapiens] 42 0.003
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 42 0.003
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 41 0.004
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 41 0.004
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 41 0.004
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 41 0.004
gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens] 41 0.004
gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens] 41 0.004
gi|28559039 mediator complex subunit 1 [Homo sapiens] 41 0.006
gi|153792110 HEG homolog 1 [Homo sapiens] 41 0.006
gi|8923106 zinc finger, CCHC domain containing 10 [Homo sapiens] 40 0.007
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 40 0.010
>gi|121114302 cullin 4B isoform 2 [Homo sapiens]
Length = 895
Score = 1751 bits (4535), Expect = 0.0
Identities = 895/895 (100%), Positives = 895/895 (100%)
Query: 1 MFPTGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDS 60
MFPTGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDS
Sbjct: 1 MFPTGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDS 60
Query: 61 TSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEES 120
TSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEES
Sbjct: 61 TSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEES 120
Query: 121 SSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLV 180
SSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLV
Sbjct: 121 SSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLV 180
Query: 181 IKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYK 240
IKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYK
Sbjct: 181 IKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYK 240
Query: 241 QLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQN 300
QLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQN
Sbjct: 241 QLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQN 300
Query: 301 SMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDL 360
SMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDL
Sbjct: 301 SMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDL 360
Query: 361 QIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQK 420
QIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQK
Sbjct: 361 QIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQK 420
Query: 421 SLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYI 480
SLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYI
Sbjct: 421 SLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYI 480
Query: 481 KAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNK 540
KAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNK
Sbjct: 481 KAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNK 540
Query: 541 PAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVG 600
PAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVG
Sbjct: 541 PAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVG 600
Query: 601 KSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELT 660
KSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELT
Sbjct: 601 KSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELT 660
Query: 661 VNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKE 720
VNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKE
Sbjct: 661 VNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKE 720
Query: 721 GKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPK 780
GKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPK
Sbjct: 721 GKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPK 780
Query: 781 GKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIM 840
GKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIM
Sbjct: 781 GKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIM 840
Query: 841 KMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 895
KMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA
Sbjct: 841 KMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 895
>gi|121114298 cullin 4B isoform 1 [Homo sapiens]
Length = 913
Score = 1742 bits (4512), Expect = 0.0
Identities = 891/891 (100%), Positives = 891/891 (100%)
Query: 5 GFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSS 64
GFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSS
Sbjct: 23 GFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSS 82
Query: 65 SSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS 124
SSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS
Sbjct: 83 SSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS 142
Query: 125 SSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLVIKNF 184
SSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLVIKNF
Sbjct: 143 SSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLVIKNF 202
Query: 185 KDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQ 244
KDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQ
Sbjct: 203 KDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQ 262
Query: 245 ICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLP 304
ICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLP
Sbjct: 263 ICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLP 322
Query: 305 SIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQ 364
SIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQ
Sbjct: 323 SIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQ 382
Query: 365 DSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIA 424
DSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIA
Sbjct: 383 DSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIA 442
Query: 425 TVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFG 484
TVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFG
Sbjct: 443 TVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFG 502
Query: 485 STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAEL 544
STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAEL
Sbjct: 503 STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAEL 562
Query: 545 IAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSAS 604
IAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSAS
Sbjct: 563 IAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSAS 622
Query: 605 VDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNIL 664
VDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNIL
Sbjct: 623 VDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNIL 682
Query: 665 TMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKE 724
TMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKE
Sbjct: 683 TMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKE 742
Query: 725 LQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDI 784
LQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDI
Sbjct: 743 LQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDI 802
Query: 785 EDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRK 844
EDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRK
Sbjct: 803 EDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRK 862
Query: 845 TLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 895
TLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA
Sbjct: 863 TLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 913
>gi|57165424 cullin 4A isoform 1 [Homo sapiens]
Length = 759
Score = 1243 bits (3217), Expect = 0.0
Identities = 620/749 (82%), Positives = 683/749 (91%), Gaps = 5/749 (0%)
Query: 150 ASVHHANGLAKSSTTVSSFANSKPGSA---KKLVIKNFKDKPKLPENYTDETWQKLKEAV 206
A V NGL K + + A +KPG A KKLVIKNF+D+P+LP+NYT +TW+KL EAV
Sbjct: 13 ALVGRTNGLTKPAALAA--APAKPGGAGGSKKLVIKNFRDRPRLPDNYTQDTWRKLHEAV 70
Query: 207 EAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHIKAQIHQFREDSLDSVL 266
A+Q+STSI+YNLEELYQAVENLCS+K+S LYKQLRQ CEDH++AQI FREDSLDSVL
Sbjct: 71 RAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDHVQAQILPFREDSLDSVL 130
Query: 267 FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQN 326
FLKKI+ CWQ+HCRQMIMIRSIFLFLDRTYVLQNS LPSIWDMGLELFR HIISD+ VQ+
Sbjct: 131 FLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIWDMGLELFRTHIISDKMVQS 190
Query: 327 KTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKL 386
KTIDGILLLIERER+GEA+DRSLLRSLL MLSDLQ+Y+DSFE +FLEETN LYAAEGQ+L
Sbjct: 191 KTIDGILLLIERERSGEAVDRSLLRSLLGMLSDLQVYKDSFELKFLEETNCLYAAEGQRL 250
Query: 387 MQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNL 446
MQEREVPEYL+HV+KRLEEE DR+ITYLD +TQK LIA VEKQLLGEHLTAILQKGL++L
Sbjct: 251 MQEREVPEYLNHVSKRLEEEGDRVITYLDHSTQKPLIACVEKQLLGEHLTAILQKGLDHL 310
Query: 447 LDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKD 506
LDENR+ DL+ +YQLFSRVRGG Q LLQ W EYIK FG+ IVINPEKDK MVQ+LLDFKD
Sbjct: 311 LDENRVPDLAQMYQLFSRVRGGQQALLQHWSEYIKTFGTAIVINPEKDKDMVQDLLDFKD 370
Query: 507 KVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELE 566
KVDH+I++CF KNE+F+N MKE+FETFINKRPNKPAELIAK+VDSKLRAGNKEATDEELE
Sbjct: 371 KVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELE 430
Query: 567 KMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSK 626
+ LDKIMI+FRFI+GKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSK
Sbjct: 431 RTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSK 490
Query: 627 LEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNILTMGYWPTYVPMEVHLPPEMVKL 686
LEGMFKDMELSKDIM+ FKQ+MQNQ+ G I+LTVNILTMGYWPTY PMEVHL PEM+KL
Sbjct: 491 LEGMFKDMELSKDIMVHFKQHMQNQSDSGPIDLTVNILTMGYWPTYTPMEVHLTPEMIKL 550
Query: 687 QEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSL 746
QE+FK FYLGKHSGRKLQWQ+TLGH VLKAEFKEGKKE QVSLFQTLVLLMFNEG+ FS
Sbjct: 551 QEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSF 610
Query: 747 EEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKIN 806
EEIK ATGIED ELRRTLQSLACGKARVL K+PKGK++EDGDKFI N +FKHKLFRIKIN
Sbjct: 611 EEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKIN 670
Query: 807 QIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPA 866
QIQMKETVEEQ STTERVFQDRQYQIDAAIVRIMKMRKTL HNLLVSE+YNQLKFPVKP
Sbjct: 671 QIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPG 730
Query: 867 DLKKRIESLIDRDYMERDKENPNQYNYIA 895
DLKKRIESLIDRDYMERDK+NPNQY+Y+A
Sbjct: 731 DLKKRIESLIDRDYMERDKDNPNQYHYVA 759
>gi|11140811 cullin 4A isoform 2 [Homo sapiens]
Length = 659
Score = 1138 bits (2943), Expect = 0.0
Identities = 564/658 (85%), Positives = 613/658 (93%)
Query: 238 LYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYV 297
LYKQLRQ CEDH++AQI FREDSLDSVLFLKKI+ CWQ+HCRQMIMIRSIFLFLDRTYV
Sbjct: 2 LYKQLRQACEDHVQAQILPFREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYV 61
Query: 298 LQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSML 357
LQNS LPSIWDMGLELFR HIISD+ VQ+KTIDGILLLIERER+GEA+DRSLLRSLL ML
Sbjct: 62 LQNSTLPSIWDMGLELFRTHIISDKMVQSKTIDGILLLIERERSGEAVDRSLLRSLLGML 121
Query: 358 SDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQT 417
SDLQ+Y+DSFE +FLEETN LYAAEGQ+LMQEREVPEYL+HV+KRLEEE DR+ITYLD +
Sbjct: 122 SDLQVYKDSFELKFLEETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLDHS 181
Query: 418 TQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWI 477
TQK LIA VEKQLLGEHLTAILQKGL++LLDENR+ DL+ +YQLFSRVRGG Q LLQ W
Sbjct: 182 TQKPLIACVEKQLLGEHLTAILQKGLDHLLDENRVPDLAQMYQLFSRVRGGQQALLQHWS 241
Query: 478 EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 537
EYIK FG+ IVINPEKDK MVQ+LLDFKDKVDH+I++CF KNE+F+N MKE+FETFINKR
Sbjct: 242 EYIKTFGTAIVINPEKDKDMVQDLLDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKR 301
Query: 538 PNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRL 597
PNKPAELIAK+VDSKLRAGNKEATDEELE+ LDKIMI+FRFI+GKDVFEAFYKKDLAKRL
Sbjct: 302 PNKPAELIAKHVDSKLRAGNKEATDEELERTLDKIMILFRFIHGKDVFEAFYKKDLAKRL 361
Query: 598 LVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNI 657
LVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIM+ FKQ+MQNQ+ G I
Sbjct: 362 LVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQHMQNQSDSGPI 421
Query: 658 ELTVNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAE 717
+LTVNILTMGYWPTY PMEVHL PEM+KLQE+FK FYLGKHSGRKLQWQ+TLGH VLKAE
Sbjct: 422 DLTVNILTMGYWPTYTPMEVHLTPEMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAE 481
Query: 718 FKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAK 777
FKEGKKE QVSLFQTLVLLMFNEG+ FS EEIK ATGIED ELRRTLQSLACGKARVL K
Sbjct: 482 FKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIK 541
Query: 778 NPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIV 837
+PKGK++EDGDKFI N +FKHKLFRIKINQIQMKETVEEQ STTERVFQDRQYQIDAAIV
Sbjct: 542 SPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIV 601
Query: 838 RIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 895
RIMKMRKTL HNLLVSE+YNQLKFPVKP DLKKRIESLIDRDYMERDK+NPNQY+Y+A
Sbjct: 602 RIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDNPNQYHYVA 659
>gi|4503165 cullin 3 [Homo sapiens]
Length = 768
Score = 503 bits (1296), Expect = e-142
Identities = 291/749 (38%), Positives = 440/749 (58%), Gaps = 48/749 (6%)
Query: 190 LPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDH 249
+ E Y + W LK A++ IQ + + EELY+ + +K LY LR++ +H
Sbjct: 25 MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEH 84
Query: 250 IKAQIHQFREDSLDSVL--FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIW 307
+ I++ RED L+S+ FL+ +++ W +H M+MIR I +++DR YV QN++ +++
Sbjct: 85 L---INKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNV-ENVY 140
Query: 308 DMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDL-----QI 362
++GL +FR ++ +++ +L +I RER GE +DR +R+ ML L +
Sbjct: 141 NLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSV 200
Query: 363 YQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSL 422
Y++ FE FLE + + E QK + E Y+ V R+ EE +R++ LD++T++ +
Sbjct: 201 YEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPI 260
Query: 423 IATVEKQLLGEHLTAILQ---KGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEY 479
+ VE++L+ +H+ I++ GL ++L + +DL +Y+LFSRV G++ + + Y
Sbjct: 261 VKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSY 320
Query: 480 IKAFGSTIVINPEKDKTMV---QELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINK 536
++ G +V + K V Q LLD K + D + F + F + FE F+N
Sbjct: 321 LREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNL 380
Query: 537 RPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKR 596
P E ++ ++D KL+ G K T++E+E +LDK M++FRF+ KDVFE +YK+ LA+R
Sbjct: 381 NSRSP-EYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARR 439
Query: 597 LLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVP-G 655
LL KS S D+EK+M+SKLK ECG FTSKLEGMF+DM +S M +F+Q++Q V G
Sbjct: 440 LLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLG 499
Query: 656 NIELTVNILTMGYWPTY-VPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVL 714
++LTV +LT GYWPT + ++PP EIF+ FYL KHSGR+L Q +G L
Sbjct: 500 GVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADL 559
Query: 715 KAEF-----KEGKKE-----------------LQVSLFQTLVLLMFNEGEEFSLEEIKQA 752
A F KE E LQVS FQ +L++FN E+++ EEI+Q
Sbjct: 560 NATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQE 619
Query: 753 TGIEDGELRRTLQSLACGK--ARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQM 810
T I + EL R LQSLACGK RVL K PK K+IE+G F ND F KL R+KI +
Sbjct: 620 TDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAA 679
Query: 811 K--ETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLK--FPVKPA 866
K E+ E+ T ++V DR+++I+AAIVRIMK RK + HN+LV+EV QLK F P
Sbjct: 680 KQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPV 739
Query: 867 DLKKRIESLIDRDYMERDKENPNQYNYIA 895
+KKRIE LI+R+Y+ R E+ Y Y+A
Sbjct: 740 VIKKRIEGLIEREYLARTPEDRKVYTYVA 768
>gi|32307161 cullin 1 [Homo sapiens]
Length = 776
Score = 339 bits (870), Expect = 6e-93
Identities = 239/768 (31%), Positives = 391/768 (50%), Gaps = 77/768 (10%)
Query: 196 DETWQKLKEAVEAIQNSTSI-KYNLEELYQAVENLCSYKISAN----------------- 237
D+ W L+ ++ + S+ K ELY V N C+ +N
Sbjct: 18 DQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQT 77
Query: 238 ----------LYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRS 287
LYK+L++ ++++ + + ED +D + LK + W+++ ++
Sbjct: 78 PGGAQFVGLELYKRLKEFLKNYL-TNLLKDGEDLMDESV-LKFYTQQWEDYRFSSKVLNG 135
Query: 288 IFLFLDRTYVLQN-----SMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNG 342
I +L+R +V + + I+ + L +R + + + + + +L LIE+ERNG
Sbjct: 136 ICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLF--RPLNKQVTNAVLKLIEKERNG 193
Query: 343 EAIDRSLLRSLLSMLSDL--------------QIYQDSFEQRFLEETNRLYAAEGQKLMQ 388
E I+ L+ ++ +L +Y++SFE +FL +T R Y E + +Q
Sbjct: 194 ETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQ 253
Query: 389 EREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLD 448
+ V EY+ RL EE R+ YL ++TQ L E+ L+ +HL I NLLD
Sbjct: 254 QNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLE-IFHTEFQNLLD 312
Query: 449 ENRIQDLSLLYQLFSRVRGGVQVLLQ--------QWIEYIKAFGSTIVINPEKDKTMVQE 500
++ +DL +Y L SR++ G+ L + Q + I+ G + +P K VQ
Sbjct: 313 ADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDP---KMYVQT 369
Query: 501 LLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRP--------NKPAELIAKYVDSK 552
+LD K + ++ F + F+ A+ +A FIN +K EL+A+Y DS
Sbjct: 370 VLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSL 429
Query: 553 LRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSML 612
L+ +K + ELE L+++M++F++I KDVF+ FY K LAKRL+ SAS DAE SM+
Sbjct: 430 LKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMI 489
Query: 613 SKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNILTMGYWPTY 672
SKLK CG +TSKL+ MF+D+ +SKD+ QFK+++ N P +++ ++ +L+ G WP
Sbjct: 490 SKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSE-PLDLDFSIQVLSSGSWPFQ 548
Query: 673 VPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQT 732
LP E+ + + F FY +HSGRKL W L L + + LQ S FQ
Sbjct: 549 QSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQM 608
Query: 733 LVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLA-KNPKGKDIE-DGDKF 790
+LL +N + ++++++ +T I+ L + LQ L K VL +N ++E D
Sbjct: 609 AILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTL 668
Query: 791 I-CNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHN 849
I +K+K R+ IN E +EQ +T + + +DR+ I AAIVRIMKMRK L H
Sbjct: 669 IKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQ 728
Query: 850 LLVSEVYNQLKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 895
L+ EV QL KP +KK I+ LI+++Y+ER + Y+Y+A
Sbjct: 729 QLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA 776
>gi|19482174 cullin 2 [Homo sapiens]
Length = 745
Score = 308 bits (790), Expect = 1e-83
Identities = 212/743 (28%), Positives = 381/743 (51%), Gaps = 51/743 (6%)
Query: 196 DETWQKLKEAVEAIQNSTSI-KYNLEELYQAVENLC---SYKISANLYKQLRQICEDHIK 251
DETW KL ++A+ + + + + + LC + LY + + E+H++
Sbjct: 11 DETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVR 70
Query: 252 AQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSM--------- 302
+H+ +S + VL + R W+ + + + ++ +L+ ++ +N +
Sbjct: 71 -HLHKRVLESEEQVLVM--YHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGY 127
Query: 303 --------LPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLL 354
L I ++ L+++R ++ + +Q I +L I+ +R GE ++ ++ ++
Sbjct: 128 GGVDMNEPLMEIGELALDMWRKLMV--EPLQAILIRMLLREIKNDRGGEDPNQKVIHGVI 185
Query: 355 SMLSD---------LQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEE 405
+ L+ YQ+ FE FL ET Y E L+QE +Y+ V RL++
Sbjct: 186 NSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKD 245
Query: 406 EADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRV 465
E R YL ++ +I +++++ +HL L +N++ + + D++ +Y L V
Sbjct: 246 EEIRCRKYLHPSSYTKVIHECQQRMVADHLQ-FLHAECHNIIRQEKKNDMANMYVLLRAV 304
Query: 466 RGGVQVLLQQWIEYIKAFG--STIVINPEKDKTM-VQELLDFKDKVDHIIDICFLKNEKF 522
G+ ++Q+ +I G +T + E T+ V+ +L+ K +I+ ++ F
Sbjct: 305 STGLPHMIQELQNHIHDEGLRATSNLTQENMPTLFVESVLEVHGKFVQLINTVLNGDQHF 364
Query: 523 INAMKEAFETFINKRPNKPA----ELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRF 578
++A+ +A + +N R K EL+AKY D+ L+ K T+ E+E L + +F++
Sbjct: 365 MSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVEDRLTSFITVFKY 424
Query: 579 IYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSK 638
I KDVF+ FY + LAKRL+ G S S+D+E++M++KLK CG FTSKL M+ DM +S
Sbjct: 425 IDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSA 484
Query: 639 DIMIQFKQYMQNQN--VPGNIELTVNILTMGYWP-TYVPMEVH-LPPEMVKLQEIFKTFY 694
D+ +F +++NQ+ + I + +L G WP T P +P E+ K ++F+ FY
Sbjct: 485 DLNNKFNNFIKNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMFELFY 544
Query: 695 LGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATG 754
SGRKL W L +K + V+ +Q VLL FN E S +E++ +T
Sbjct: 545 SQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSETVSYKELQDSTQ 604
Query: 755 IEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETV 814
+ + EL +T++SL +++ + + +DI+ F N +F K + KI K+T
Sbjct: 605 MNEKELTKTIKSLL--DVKMINHDSEKEDIDAESSFSLNMNFSSKRTKFKITTSMQKDTP 662
Query: 815 EEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKP--ADLKKRI 872
+E T V +DR+ + AAIVRIMK RK L HN L+ EV +Q + P + +KK I
Sbjct: 663 QEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKKCI 722
Query: 873 ESLIDRDYMERDKENPNQYNYIA 895
E LID+ Y+ER + + ++Y+Y+A
Sbjct: 723 EVLIDKQYIERSQASADEYSYVA 745
>gi|40254446 Vasopressin-activated calcium-mobilizing receptor-1
[Homo sapiens]
Length = 780
Score = 238 bits (608), Expect = 1e-62
Identities = 209/773 (27%), Positives = 378/773 (48%), Gaps = 81/773 (10%)
Query: 196 DETWQKLKEAVEAIQNSTSI-KYNLEELYQAVENLCSY--KISANLYKQLRQICEDHIKA 252
++ W ++ V + S+ K +L+ V +C + K A +++ L++ + IK
Sbjct: 16 EDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQ 75
Query: 253 QIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYV-LQNSMLPS------ 305
+ D+ L LK W+ Q ++ F L+ T + Q S S
Sbjct: 76 AQARVLSHQDDTAL-LKAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSI 134
Query: 306 IWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLL----RSLLSMLSD-- 359
+ + L+ + I S+ ++N+ D + L+ ER GEA D L+ S +++ S+
Sbjct: 135 VRKLMLDTWNESIFSN--IKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPE 192
Query: 360 --LQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQT 417
LQIY+D+FE+ +L+ T R Y + +Q+ V Y+ + + +L+EE R + YL+
Sbjct: 193 DKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETR 252
Query: 418 TQKSLIATVEKQLLGEHLTAILQKGL---NNLLDENRIQDLSLLYQLFSRVRGGVQVLLQ 474
+ + + + + + +T+ + L ++ N + L L++ L +V G++ +L+
Sbjct: 253 RECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLK 312
Query: 475 QWIEYIKAFG--------STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAM 526
E+I + G TI + EK V++LL ++ ++ F + +F+ A
Sbjct: 313 DLEEHIISAGLADMVAAAETITTDSEK---YVEQLLTLFNRFSKLVKEAFQDDPRFLTAR 369
Query: 527 KEAFETFIN--------------------KRPNKPAELIAKYVDSKLRAG--NKEATDEE 564
+A++ +N + +K EL+A Y D LR +K+ T EE
Sbjct: 370 DKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEE 429
Query: 565 LEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECG--AA 622
+E L +++++ +++ KDVF ++K L +RL++ SA + E++M+ L+ E G A
Sbjct: 430 IEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLR-EVGMPAD 488
Query: 623 FTSKLEGMFKDMELSKDIMIQFKQYMQNQN--VPGNIELTVNILTMGYWP-TYVPMEVHL 679
+ +KL MF+D+++S+D+ FK+ +N +P + + + IL G W + + V L
Sbjct: 489 YVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPAD-SVNIKILNAGAWSRSSEKVFVSL 547
Query: 680 PPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFN 739
P E+ L + FY HSGRKL W + + ++ + + G+ +L+V+ FQ VL +N
Sbjct: 548 PTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWN 607
Query: 740 E--GEEFSLEEIKQATGIEDGELRRTLQSLACG---KARVLAKNPK---GKDIEDGDKFI 791
+ E+ S E +K AT + D ELRRTL SL K +VL P+ KD +G F
Sbjct: 608 QRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFS 667
Query: 792 CNDDFK-----HKLFRIKINQIQMKETVEE--QASTTERVFQDRQYQIDAAIVRIMKMRK 844
N +F R KIN I + E + E + Q R + AI++IMKMRK
Sbjct: 668 VNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRK 727
Query: 845 TLSHNLLVSEVYNQLK--FPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 895
+S+ L +E+ LK F + +K++IE LI+ Y+ RD+ + N + Y+A
Sbjct: 728 KISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA 780
>gi|7019327 anaphase-promoting complex subunit 2 [Homo sapiens]
Length = 822
Score = 62.8 bits (151), Expect = 1e-09
Identities = 53/189 (28%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 579 IYG-KDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELS 637
IYG KD+F Y+ LA RLL S S + E + LK G A E M KDM S
Sbjct: 508 IYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADS 567
Query: 638 KDIMIQFKQYMQNQNVPGNIELTVN--ILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYL 695
+ I ++ + + V IL+ +WP + ++ +P ++ E + Y
Sbjct: 568 RRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYE 627
Query: 696 GKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGI 755
+ R L W+ TLG + E + + V+ Q ++LL F + ++LEE+ +A +
Sbjct: 628 QLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQDQASWTLEELSKAVKM 687
Query: 756 EDGELRRTL 764
LRR +
Sbjct: 688 PVALLRRRM 696
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 18/176 (10%)
Query: 3 PTGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTS 62
P + PSA AA Q + ++S++ +S+ +SSSSSSS SS S+
Sbjct: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSS-------SSD 2562
Query: 63 SSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSS 122
S S+ P+QP + V + + P ++ +R E K SSS
Sbjct: 2563 SEGSSLPVQPEVALK----------RVPSPTPAP-KEAVREGRPPEPTPAKRKRRSSSSS 2611
Query: 123 SSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKK 178
SSSSSS ++++S + S SS +S ++ + S A KP S KK
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK 2667
Score = 35.0 bits (79), Expect = 0.31
Identities = 47/186 (25%), Positives = 65/186 (34%), Gaps = 13/186 (6%)
Query: 9 PSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTP 68
P+P VR ++ + T KK+K S SS+ ER+ S
Sbjct: 163 PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222
Query: 69 PLQPRDSASPSTSSFCLGVS---VAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSS 125
+ R SP+ S + S P K R + A A S +S S
Sbjct: 223 ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST-----SADSASSSDTSRS 277
Query: 126 SSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSST--TVSSFANSKPGSAKKLVIKN 183
S AA + L +S S AS G A S T S+ S P +A K
Sbjct: 278 RSRSAAAKTHTTALAGRS---PSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP 334
Query: 184 FKDKPK 189
++DK K
Sbjct: 335 YEDKDK 340
Score = 33.9 bits (76), Expect = 0.69
Identities = 32/124 (25%), Positives = 47/124 (37%), Gaps = 4/124 (3%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SSP P A RS + + +R+ + S SS + R S S S
Sbjct: 1482 SSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGS 1541
Query: 67 TPPLQPRDSASP-STSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSS 125
+ L + SASP S A + P++++ R + E D+K S S
Sbjct: 1542 SQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPE---VDSKSRLSPRRSRS 1598
Query: 126 SSSP 129
SSP
Sbjct: 1599 GSSP 1602
Score = 32.7 bits (73), Expect = 1.5
Identities = 37/140 (26%), Positives = 55/140 (39%), Gaps = 7/140 (5%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SSP P + +S ++S++P K S +S +NE+ S
Sbjct: 819 SSPPPKQKSKTPSRQS----HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874
Query: 67 TPPLQPRDSASPSTSSFCLGVSV--AASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS 124
+ P S +PS S C G S SS P Q R V + S S S
Sbjct: 875 SSPDPELKSRTPSRHS-CSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS 933
Query: 125 SSSSPTAATSQQQQLKNKSI 144
SS SP+ TS+ +++S+
Sbjct: 934 SSPSPSRVTSRTTPRRSRSV 953
Score = 32.0 bits (71), Expect = 2.6
Identities = 20/72 (27%), Positives = 37/72 (51%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS S S+++++ S++ ++S++ +S+ +SSSSSS + + +S
Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666
Query: 67 TPPLQPRDSASP 78
PP R S SP
Sbjct: 2667 KPPPGERRSRSP 2678
Score = 30.4 bits (67), Expect = 7.7
Identities = 37/177 (20%), Positives = 62/177 (35%), Gaps = 20/177 (11%)
Query: 4 TGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSS 63
+G S AA +S +D + P + + S SSS E ST S
Sbjct: 1598 SGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTES 1657
Query: 64 SSSTPPLQ------PRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMA 117
S PP R S P T S ++ S + +K R
Sbjct: 1658 SPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL-------------- 1703
Query: 118 EESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPG 174
S S+SSS T + + + ++ S+ A ++ +S+++ + S+ G
Sbjct: 1704 SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRG 1760
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 48.5 bits (114), Expect = 3e-05
Identities = 41/142 (28%), Positives = 65/142 (45%), Gaps = 10/142 (7%)
Query: 4 TGFSSPSPSAAAAAQEVRSATDGNTS----------TTPPTSAKKRKLNSSSSSSSNSSN 53
+G SS S S++++ E +G+ + S++ SSSSSSS+SS+
Sbjct: 2565 SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSS 2624
Query: 54 EREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFD 113
S+SSSSS+ S+S S+SS S ++SS ED+ +
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDE 2684
Query: 114 AKMAEESSSSSSSSSPTAATSQ 135
A A + S+ ++ PT AT Q
Sbjct: 2685 AAPAPTAGPSAQAALPTKATKQ 2706
Score = 42.7 bits (99), Expect = 0.001
Identities = 48/192 (25%), Positives = 79/192 (41%), Gaps = 37/192 (19%)
Query: 10 SPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTS------- 62
SP A A Q+ ++ ++S++ +S+ +SSSSSSS S E E+ +
Sbjct: 2543 SPDKAQAEQDGAEESESSSSSSSGSSS-----SSSSSSSSGSETEGEEEGDKNGDGGCGT 2597
Query: 63 -----SSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMA 117
S++S+ P S+S S+SS S ++SS + +
Sbjct: 2598 GGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSS--------------------SSSS 2637
Query: 118 EESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAK 177
SSSSSSSSS ++++S + S SS +S + S + + P +
Sbjct: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQA 2697
Query: 178 KLVIKNFKDKPK 189
L K K K
Sbjct: 2698 ALPTKATKQAGK 2709
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/80 (27%), Positives = 45/80 (56%)
Query: 3 PTGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTS 62
P SS S S+++++ S++ ++S++ +S+ +SSSSSSS+SS+ S+S
Sbjct: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671
Query: 63 SSSSTPPLQPRDSASPSTSS 82
++ D A+P+ ++
Sbjct: 2672 TTDEDSSCSSDDEAAPAPTA 2691
Score = 41.2 bits (95), Expect = 0.004
Identities = 46/171 (26%), Positives = 70/171 (40%), Gaps = 37/171 (21%)
Query: 23 ATDGNTSTTP--------------PTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTP 68
ATDG+ + P P A+ + + S SS+SS+ S+SSSSS
Sbjct: 2520 ATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGS 2579
Query: 69 PLQPRDSASPSTSSFCLGVS----VAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS 124
+ + + C G AASS A A SSSSS
Sbjct: 2580 ETEGEEEGDKNGDGGC-GTGGRNCSAASSRA------------------ASPASSSSSSS 2620
Query: 125 SSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGS 175
SSSS ++++S + S SS +S ++ + SS++ SS ++S S
Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671
Score = 40.4 bits (93), Expect = 0.007
Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 20/151 (13%)
Query: 26 GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCL 85
GN + A++ S SSSS+SS S+SSS S + +
Sbjct: 2539 GNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTG 2598
Query: 86 GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSIL 145
G + +A+S ++ A +SSSSSSSS ++++S + S
Sbjct: 2599 GRNCSAAS--------------------SRAASPASSSSSSSSSSSSSSSSSSSSSSSSS 2638
Query: 146 ISSVASVHHANGLAKSSTTVSSFANSKPGSA 176
SS +S ++ + SS++ SS ++S S+
Sbjct: 2639 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2669
Score = 39.7 bits (91), Expect = 0.013
Identities = 24/93 (25%), Positives = 48/93 (51%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS S S+++++ S++ ++S++ +S+ +SSSSSSS++++E S ++
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAP 2687
Query: 67 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQK 99
P P A+ T + S+H P +K
Sbjct: 2688 APTAGPSAQAALPTKATKQAGKARPSAHSPGKK 2720
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 47.8 bits (112), Expect = 5e-05
Identities = 43/174 (24%), Positives = 79/174 (45%), Gaps = 4/174 (2%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS S ++ ++ S+ +++ + +S NSS S SS+SSN + DS++SS S
Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923
Query: 67 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSS 126
+ D+++ S SS S ++ S + + D+ ++ S SS+SS
Sbjct: 924 SESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983
Query: 127 ----SSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSA 176
SS ++ +S N S S S +N S+++ SS ++ S+
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Score = 47.0 bits (110), Expect = 8e-05
Identities = 41/169 (24%), Positives = 75/169 (44%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS S ++ ++ S+ N+S + +S +S SS SSNSS+ + DS+ SS S
Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS 997
Query: 67 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSS 126
+ DS+ S SS S +++S + + D+ + +SS SS+S
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057
Query: 127 SSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGS 175
S + ++ + SS +S + + +S+ S ++S S
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS 1106
Score = 46.6 bits (109), Expect = 1e-04
Identities = 44/171 (25%), Positives = 78/171 (45%), Gaps = 6/171 (3%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS S ++ ++ S+ ++S + +S +SS+SS S+ S++ D DS++SS S
Sbjct: 767 SSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS 826
Query: 67 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEES--SSSS 124
+ DS++ S SS S + S R + + D+ + S SS S
Sbjct: 827 SNSSDSSDSSNSSDSSDSSDSSDGSDS----DSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882
Query: 125 SSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGS 175
S S+ ++ +S N S SS +S + + +S+ S +NS S
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNS 933
Score = 45.1 bits (105), Expect = 3e-04
Identities = 45/171 (26%), Positives = 75/171 (43%), Gaps = 10/171 (5%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS S +++ ++ S + + S++ S+ +SS S SS+SSN + DS+ SS S
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613
Query: 67 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSS 126
+ DS S S+ S S K D+ D + +SS+SS+S
Sbjct: 614 SDSSDSSDSKSDSSKS--------ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 127 --SSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGS 175
SS ++ +S + S S S +N S ++ SS ++S S
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716
Score = 43.9 bits (102), Expect = 7e-04
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS S ++ ++ S++ ++S + +S NSS SS S+ S++ + DS+ SS+S
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Query: 67 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSS 126
DS++ S SS S ++ S D+ + SS SS
Sbjct: 722 NS--SDSDSSNSSDSSDSSNSSDSSDS----SDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775
Query: 127 SSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGS 175
SS ++ +S N S S S +N S ++ SS ++S S
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824
Score = 43.9 bits (102), Expect = 7e-04
Identities = 37/138 (26%), Positives = 66/138 (47%), Gaps = 7/138 (5%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSS-SSNSSNEREDFDSTSSSS 65
SS S ++ ++ S+ ++S + +S NSS SS SS+SS+ + DS+ SS
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203
Query: 66 STPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSS 125
S+ DS+ S SS S ++ S+ + + D+ + +SS SS
Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS------DSSNSSDSSDSSD 1257
Query: 126 SSSPTAATSQQQQLKNKS 143
SS T+ ++ + ++KS
Sbjct: 1258 SSDSTSDSNDESDSQSKS 1275
Score = 43.5 bits (101), Expect = 9e-04
Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 5/169 (2%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
S S S+ ++ S +D + S+ S +S+SS SS+SSN + DS+ SS+S
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752
Query: 67 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSS 126
+ DS++ S SS S ++ S + + D+ + +SS+SS S
Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN---DSSNSSDSSDSSNSSDSSNSSDS 809
Query: 127 SSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGS 175
S ++ S N S +S S +N S ++ SS + S
Sbjct: 810 SD--SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856
Score = 41.2 bits (95), Expect = 0.004
Identities = 40/169 (23%), Positives = 73/169 (43%), Gaps = 2/169 (1%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS S +++ ++ S+ ++S + +S +S SS SSNSS+ + DS+ SS S
Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE--SSDSSDSSNSSDSSDSSDSSDSSDS 1108
Query: 67 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSS 126
+ DS+ S SS S ++ S + + D+ + +SS SS S
Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS 1168
Query: 127 SSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGS 175
S + ++ + SS +S + + S+ S ++S S
Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1217
Score = 40.8 bits (94), Expect = 0.006
Identities = 43/170 (25%), Positives = 72/170 (42%), Gaps = 6/170 (3%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS S ++ ++ S+ N+S + +S +S SS SS+SS+ E DS+ SS+S
Sbjct: 1036 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSSDSSESSDSSDSSNS 1093
Query: 67 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSS 126
+ DS+ S SS S ++ S D+ + SS SS
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDS----SNSSDSSDSSDSSDSSDSSNSSDSSDSSE 1149
Query: 127 SSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSA 176
SS ++ +S + S S S +N S ++ SS ++ S+
Sbjct: 1150 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199
Score = 38.1 bits (87), Expect = 0.037
Identities = 37/164 (22%), Positives = 71/164 (43%), Gaps = 1/164 (0%)
Query: 8 SPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSST 67
S S + + + S+ N+S + +S ++SSS S +S ++ D + SS S+
Sbjct: 540 SDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSS 599
Query: 68 PPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSS 127
DS+ S SS S + S + D+ + D+ ++ S +S SS
Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS-KSDSSDSNSSDSSDNSDSSD 658
Query: 128 SPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANS 171
S ++ S + S SS + +++ + SS + +S +S
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702
Score = 34.3 bits (77), Expect = 0.53
Identities = 33/159 (20%), Positives = 65/159 (40%), Gaps = 6/159 (3%)
Query: 19 EVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASP 78
+ S +D N+S+ S + + + S + E +D DSTS ++++ ++ +
Sbjct: 476 DANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND 535
Query: 79 STSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQ 138
G + SS D+ + D+ + SS S SS S ++ +S
Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDS 595
Query: 139 LKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAK 177
+ + SS +S + S+ S ++SK S+K
Sbjct: 596 SDSSNSSDSSDSSD------SSDSSDSSDSSDSKSDSSK 628
>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
sapiens]
Length = 2517
Score = 47.4 bits (111), Expect = 6e-05
Identities = 69/301 (22%), Positives = 123/301 (40%), Gaps = 72/301 (23%)
Query: 542 AELIAKYVDSKLRAGNKEATDE-----ELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKR 596
+E A+Y+D +++ G +L++ L+ IM++ FE FY+ +A R
Sbjct: 1546 SEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELAT-TFEHFYQHYMADR 1604
Query: 597 LLVGKSASVDAEKSMLSKLKHECGAAFTSKL-EGMFKDMELSKDIMIQFKQYM------- 648
LL S+ ++ + + G F ++L + M + + S+++ QF +
Sbjct: 1605 LLSFGSSWLEGA------VLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKL 1658
Query: 649 ---QNQNVPGNIE-----------------------LTVNILTMGYWPT------YVPME 676
Q +E +++ +L+ WP Y P +
Sbjct: 1659 FLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRK 1718
Query: 677 VHLPPEMVKLQEIFKTFY----------LGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQ 726
LP E + F +FY +G H R+LQW + LG +AE + GK+ L
Sbjct: 1719 C-LPTEFCDALDRFSSFYSQSQNHPVLDMGPH--RRLQW-TWLG----RAELQFGKQILH 1770
Query: 727 VSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIED 786
VS Q +LL FN+ EE S+E + + + + L + L L G + +G+D
Sbjct: 1771 VSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLH--EGQDFPH 1828
Query: 787 G 787
G
Sbjct: 1829 G 1829
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 44.7 bits (104), Expect = 4e-04
Identities = 44/139 (31%), Positives = 62/139 (44%), Gaps = 29/139 (20%)
Query: 30 TTPPTSAKKR--KLNSSSSSSSNSSNEREDFD--STSSSSSTPPLQPRDSASPSTSSFCL 85
T P S K R K S SSS S+S +ER S+SSSSS+ R +S S+SS C
Sbjct: 2113 TPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCS 2172
Query: 86 GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSIL 145
S ++SS SSSSSSSSS + + +++ K +S
Sbjct: 2173 SASSSSSS----------------------STSSSSSSSSSSSEESDSDEEEAQKRES-- 2208
Query: 146 ISSVASVHHANGLAKSSTT 164
++ + +A STT
Sbjct: 2209 -TTHMKAYDEESVASLSTT 2226
Score = 37.7 bits (86), Expect = 0.048
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 4/127 (3%)
Query: 10 SPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPP 69
+P+ A+ V ++S + S + + SSSSSS+SS S+SSSSS+
Sbjct: 2113 TPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCS 2172
Query: 70 LQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSP 129
S+S ++SS S + S ++ + E T +D EES +S S++
Sbjct: 2173 SASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYD----EESVASLSTTQD 2228
Query: 130 TAATSQQ 136
S Q
Sbjct: 2229 ETQDSFQ 2235
Score = 35.0 bits (79), Expect = 0.31
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSS-- 64
SS S S+++ + ++ ++S+ S+ SSSSSSS+SS+E D D +
Sbjct: 2147 SSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKR 2206
Query: 65 SSTPPLQPRDSASPSTSS 82
ST ++ D S ++ S
Sbjct: 2207 ESTTHMKAYDEESVASLS 2224
Score = 32.3 bits (72), Expect = 2.0
Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 8 SPSPSAAAAAQEVRSATDGNTSTTPPTSAK-KRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
S S S + + E S + ++S++ +S R +SSSSSSS SS STSSSSS
Sbjct: 2128 SESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSS 2187
Query: 67 TPPLQPRDSAS 77
+ +S S
Sbjct: 2188 SSSSSSEESDS 2198
Score = 30.8 bits (68), Expect = 5.9
Identities = 19/69 (27%), Positives = 36/69 (52%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS + + S + ++S++ + ++ +SSSSS S++S+ S+SSSSS
Sbjct: 2130 SSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSS 2189
Query: 67 TPPLQPRDS 75
+ + DS
Sbjct: 2190 SSSSEESDS 2198
Score = 30.4 bits (67), Expect = 7.7
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 6/74 (8%)
Query: 8 SPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSST 67
S S S+++++ SA+ ++S+T +S+ SSSSSS S ++ E+ S++
Sbjct: 2159 SRSGSSSSSSSSCSSASSSSSSSTSSSSS------SSSSSSEESDSDEEEAQKRESTTHM 2212
Query: 68 PPLQPRDSASPSTS 81
AS ST+
Sbjct: 2213 KAYDEESVASLSTT 2226
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 43.9 bits (102), Expect = 7e-04
Identities = 49/173 (28%), Positives = 80/173 (46%), Gaps = 30/173 (17%)
Query: 7 SSPSPSAAAAAQEVRSATDG-------NTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFD 59
SS + S A A S+T N+ ++ P+S NS SS++S+ +N + D
Sbjct: 260 SSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSD 319
Query: 60 STSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEE 119
S+++SS +S S +TSS G S A +S E + G A A
Sbjct: 320 SSTTSSGAS--TATNSESSTTSS---GASTATNS----------ESSTTSSG--ASTATN 362
Query: 120 SSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSK 172
S SS++SS + AT+ ++S +SS AS + + +S+ S+ NS+
Sbjct: 363 SGSSTTSSGTSTATN------SESSTVSSGASTATTSESSTTSSGASTATNSE 409
Score = 43.5 bits (101), Expect = 9e-04
Identities = 46/177 (25%), Positives = 80/177 (45%), Gaps = 22/177 (12%)
Query: 6 FSSPSPSAAAAAQEVRSATDGNTST------TPPTSAKKRKLNSSSSSSSNSSNEREDFD 59
FS+ S + A S T ST + P+S NS SS++S+ ++ + D
Sbjct: 95 FSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSD 154
Query: 60 STSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEE 119
S+++SS +S S +TSS G S A +S T+ A +E
Sbjct: 155 SSTTSSEAS--TATNSESSTTSS---GASTATNSE---------SSTVSSRASTATNSES 200
Query: 120 SSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSA 176
S++SS +S TA S+ + N + ++ S ++G + ++ + SS +S G+A
Sbjct: 201 STTSSGAS--TATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTA 255
Score = 41.2 bits (95), Expect = 0.004
Identities = 45/177 (25%), Positives = 70/177 (39%), Gaps = 19/177 (10%)
Query: 4 TGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSS 63
T S +PS+ A+ +AT+ ++STT ++ +SS++SS S+ + +TSS
Sbjct: 121 TNSESSTPSSGAS-----TATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSS 175
Query: 64 SSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSS 123
+ST + S S+ S SS T G A S SS
Sbjct: 176 GASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAG----TATNSESS 231
Query: 124 SSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLV 180
++SS + AT+ + SS S S+T SS A + S V
Sbjct: 232 TTSSGASTATNSE----------SSTPSSGAGTATNSESSTTSSGAGTATNSESSTV 278
Score = 40.8 bits (94), Expect = 0.006
Identities = 45/173 (26%), Positives = 70/173 (40%), Gaps = 21/173 (12%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
S+PS A A S T +T T++ +S +S+++NS + +TSS +S
Sbjct: 291 STPSSGANTATNSESSTTSSGANTA--TNSDSSTTSSGASTATNSES-----STTSSGAS 343
Query: 67 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSS 126
T +S S +TSS + + SS V A A S SS++S
Sbjct: 344 T----ATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTS 399
Query: 127 SSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKL 179
S + AT+ + SS S + S+T SS AN+ S +
Sbjct: 400 SGASTATNSE----------SSTVSSGASTATNSESSTTSSGANTATNSGSSV 442
Score = 37.4 bits (85), Expect = 0.063
Identities = 42/181 (23%), Positives = 77/181 (42%), Gaps = 16/181 (8%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDS---TSS 63
SS + S A+ A S T N + T T+++ +S +S+++NS + + T+S
Sbjct: 200 SSTTSSGASTATNSESRTTSNGAGTA-TNSESSTTSSGASTATNSESSTPSSGAGTATNS 258
Query: 64 SSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKK-----LRFEDTLEFVGFDAKMAE 118
SST + + +S+ G+S +S E + G +
Sbjct: 259 ESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNS 318
Query: 119 ESSSSSS-------SSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANS 171
+SS++SS S S T ++ ++S SS AS +G + +S+ S+ NS
Sbjct: 319 DSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNS 378
Query: 172 K 172
+
Sbjct: 379 E 379
Score = 31.2 bits (69), Expect = 4.5
Identities = 34/144 (23%), Positives = 59/144 (40%), Gaps = 20/144 (13%)
Query: 4 TGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSS 63
T +S S + ++ A +AT+ +STT ++ SS+ SS S+ + +TSS
Sbjct: 344 TATNSESSTTSSGAS---TATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSS 400
Query: 64 SSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSS 123
+ST + + +S+ G S A +S E + G + SS +
Sbjct: 401 GAST-------ATNSESSTVSSGASTATNS----------ESSTTSSGANTATNSGSSVT 443
Query: 124 SSSSSPTAATSQQQQLKNKSILIS 147
S+ S A T + S +S
Sbjct: 444 SAGSGTAALTGMHTTSHSASTAVS 467
>gi|40807452 peroxisome proliferator-activated receptor gamma,
coactivator-related 1 [Homo sapiens]
Length = 1664
Score = 42.4 bits (98), Expect = 0.002
Identities = 41/140 (29%), Positives = 64/140 (45%), Gaps = 11/140 (7%)
Query: 10 SPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS------SSSSSSNSSNEREDFDSTSS 63
+PS+ + + D NT T P SAK+R + S+S SS R +S S
Sbjct: 1371 APSSLLSPEASPCRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRRGRNSRSV 1430
Query: 64 SSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSS 123
SS + S+S S+SS S + S P K+ R ++ SSSS
Sbjct: 1431 SSGSNRTSEASSSSSSSSSSSRSRSRSLS---PPHKRWRRSSCSS--SGRSRRCSSSSSS 1485
Query: 124 SSSSSPTAATSQQQQLKNKS 143
SSSSS ++++S + +++S
Sbjct: 1486 SSSSSSSSSSSSSSRSRSRS 1505
Score = 36.2 bits (82), Expect = 0.14
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 16/115 (13%)
Query: 4 TGFSSPSPSAAAAAQEVRSATDGNTSTTPP----------TSAKKRKLNSSSSSSSNSSN 53
+G + S ++++++ S+ + S +PP +S + R+ +SSSSSSS+SS+
Sbjct: 1432 SGSNRTSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSS 1491
Query: 54 EREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLE 108
S+ S S +P + R SS+ + H Q+ L+ E +E
Sbjct: 1492 SSSSSSSSRSRSRSPSPRRRSDRRRRYSSY------RSHDHYQRQRVLQKERAIE 1540
Score = 33.9 bits (76), Expect = 0.69
Identities = 42/175 (24%), Positives = 72/175 (41%), Gaps = 18/175 (10%)
Query: 5 GFSSPSPSAAAAAQEVRSATDGNTSTTP--PTSAKKRKLNSSSSSSSNSSNEREDFDSTS 62
G ++P P AA++E + P P A L+ +S N N R + ++
Sbjct: 1338 GPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNTRTPPEPSA 1397
Query: 63 SSSSTPPLQPR-DSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESS 121
S + SASPS+ + + R ++ + +E SS
Sbjct: 1398 KQRSMRCYRKACRSASPSSQGW---------------QGRRGRNSRSVSSGSNRTSEASS 1442
Query: 122 SSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSA 176
SSSSSSS + + S+ +K SS +S + + SS++ SS ++S S+
Sbjct: 1443 SSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSS 1497
>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
[Homo sapiens]
Length = 909
Score = 41.6 bits (96), Expect = 0.003
Identities = 40/177 (22%), Positives = 72/177 (40%), Gaps = 19/177 (10%)
Query: 7 SSPSPSAAAAAQEVRS-ATDGNTS---TTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTS 62
S+PS S++ E S +T G TS TT TS SS +++ +S++ F S+
Sbjct: 180 STPSFSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTTETTSHDTPSFTSSI 239
Query: 63 SSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSS 122
++S TP ++PS++S + S + +T S+
Sbjct: 240 TTSETP-----SHSTPSSTSLITTTKTTSHSTPSFTSSITTTET----------TSHSAH 284
Query: 123 SSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKL 179
S +SS T T+ S + ++ + H S TT + ++S P + +
Sbjct: 285 SFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSI 341
Score = 33.5 bits (75), Expect = 0.91
Identities = 40/176 (22%), Positives = 69/176 (39%), Gaps = 19/176 (10%)
Query: 6 FSSPSPSAAAAAQEVRSATDGNTST------TPP--TSAKKRKLNSSSSSSSNSSNERED 57
F+S + + S T NT T TP TS + SSS+ S +SS +
Sbjct: 133 FTSSIRTTETTSYSTPSFTSSNTITETTSHSTPSYITSITTTETPSSSTPSFSSSITTTE 192
Query: 58 FDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVG--FDAK 115
S S+ T + ++ S ST SF ++ ++ DT F ++
Sbjct: 193 TTSHSTPGFTSSITTTETTSHSTPSFTSSITTTETTS---------HDTPSFTSSITTSE 243
Query: 116 MAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANS 171
S+ SS+S T T+ S + ++ + H A+ S TT + +++
Sbjct: 244 TPSHSTPSSTSLITTTKTTSHSTPSFTSSITTTETTSHSAHSFTSSITTTETTSHN 299
>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
Length = 737
Score = 41.6 bits (96), Expect = 0.003
Identities = 42/182 (23%), Positives = 77/182 (42%), Gaps = 22/182 (12%)
Query: 4 TGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSS 63
T + P P++ + V S+T + PP S +S+SS SS+ STSS
Sbjct: 73 TSATRPPPASNEVSTSVLSST---ITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSS 129
Query: 64 ------SSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMA 117
++ST ++S +TS+ S++ +S I + T
Sbjct: 130 FITSSFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSISSSITSTST----------- 178
Query: 118 EESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAK 177
S++S+SS+S T+ + + S S+ ++ + +ST+ +S + S S +
Sbjct: 179 --STTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTTSTSTSATSSIR 236
Query: 178 KL 179
KL
Sbjct: 237 KL 238
Score = 35.0 bits (79), Expect = 0.31
Identities = 35/157 (22%), Positives = 66/157 (42%), Gaps = 18/157 (11%)
Query: 26 GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRD------SASPS 79
G T PP + +S++ +SNE +S+ + PP+ +++ S
Sbjct: 56 GERDTAPPLMLPGPTIATSATRPPPASNEVSTSVLSSTITPAPPMSVLSHHTLHITSNSS 115
Query: 80 TSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQL 139
TSS S + SS + T F + +SS+SS ++ TA TS +
Sbjct: 116 TSSSSTTSSTSTSSFI----------TSSFT--TSTSITSTSSTSSFTTSTATTSTSISI 163
Query: 140 KNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSA 176
+ S + SS+ S + S++T S+ ++ ++
Sbjct: 164 TSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTS 200
Score = 33.5 bits (75), Expect = 0.91
Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 4 TGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSS 63
T +S S S + + S T +TSTT +S NS++S+ +++S STS+
Sbjct: 154 TATTSTSISITSTSSISSSITSTSTSTTSTSS------NSTTSTVTSTSTSTSTSTSTST 207
Query: 64 SSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKK 100
SS+ + S ST+S + + P QK+
Sbjct: 208 SSTFTSTTSTSTTSTSTTSTSTSATSSIRKLTPHQKQ 244
Score = 33.1 bits (74), Expect = 1.2
Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
+S S ++ ++ + T +TST+ TS +S++S+S +S STS++SS
Sbjct: 176 TSTSTTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTTS-TSTSATSS 234
Query: 67 TPPLQP-RDSASPSTSSFCLGVSVAASS 93
L P + S+F G+S+ S+
Sbjct: 235 IRKLTPHQKQCGALASAFLFGLSLLVST 262
>gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]
Length = 737
Score = 41.6 bits (96), Expect = 0.003
Identities = 42/182 (23%), Positives = 77/182 (42%), Gaps = 22/182 (12%)
Query: 4 TGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSS 63
T + P P++ + V S+T + PP S +S+SS SS+ STSS
Sbjct: 73 TSATRPPPASNEVSTSVLSST---ITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSS 129
Query: 64 ------SSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMA 117
++ST ++S +TS+ S++ +S I + T
Sbjct: 130 FITSSFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSISSSITSTST----------- 178
Query: 118 EESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAK 177
S++S+SS+S T+ + + S S+ ++ + +ST+ +S + S S +
Sbjct: 179 --STTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTTSTSTSATSSIR 236
Query: 178 KL 179
KL
Sbjct: 237 KL 238
Score = 35.0 bits (79), Expect = 0.31
Identities = 35/157 (22%), Positives = 66/157 (42%), Gaps = 18/157 (11%)
Query: 26 GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRD------SASPS 79
G T PP + +S++ +SNE +S+ + PP+ +++ S
Sbjct: 56 GERDTAPPLMLPGPTIATSATRPPPASNEVSTSVLSSTITPAPPMSVLSHHTLHITSNSS 115
Query: 80 TSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQL 139
TSS S + SS + T F + +SS+SS ++ TA TS +
Sbjct: 116 TSSSSTTSSTSTSSFI----------TSSFT--TSTSITSTSSTSSFTTSTATTSTSISI 163
Query: 140 KNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSA 176
+ S + SS+ S + S++T S+ ++ ++
Sbjct: 164 TSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTS 200
Score = 33.5 bits (75), Expect = 0.91
Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 4 TGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSS 63
T +S S S + + S T +TSTT +S NS++S+ +++S STS+
Sbjct: 154 TATTSTSISITSTSSISSSITSTSTSTTSTSS------NSTTSTVTSTSTSTSTSTSTST 207
Query: 64 SSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKK 100
SS+ + S ST+S + + P QK+
Sbjct: 208 SSTFTSTTSTSTTSTSTTSTSTSATSSIRKLTPHQKQ 244
Score = 33.1 bits (74), Expect = 1.2
Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
+S S ++ ++ + T +TST+ TS +S++S+S +S STS++SS
Sbjct: 176 TSTSTTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTTS-TSTSATSS 234
Query: 67 TPPLQP-RDSASPSTSSFCLGVSVAASS 93
L P + S+F G+S+ S+
Sbjct: 235 IRKLTPHQKQCGALASAFLFGLSLLVST 262
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 41.6 bits (96), Expect = 0.003
Identities = 26/75 (34%), Positives = 40/75 (53%)
Query: 8 SPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSST 67
S + + + + R+ T + S + +S+ SSSS SS+SS S+SSSSST
Sbjct: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
Query: 68 PPLQPRDSASPSTSS 82
RDS+S ++SS
Sbjct: 614 SGSSSRDSSSSTSSS 628
Score = 37.4 bits (85), Expect = 0.063
Identities = 21/60 (35%), Positives = 41/60 (68%), Gaps = 3/60 (5%)
Query: 8 SPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSST 67
S S S+++++ S++ G++S++ +S++ +SSSSSS++ S+ R+ STSSSS +
Sbjct: 575 SRSSSSSSSSSSSTSSSSGSSSSSGSSSSRS---SSSSSSSTSGSSSRDSSSSTSSSSES 631
Score = 32.7 bits (73), Expect = 1.5
Identities = 32/110 (29%), Positives = 47/110 (42%), Gaps = 24/110 (21%)
Query: 30 TTPPTSAKKRKLNSSSS----SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCL 85
T P S K K S S + ++ S R S+SSSSST S+S S+SS
Sbjct: 547 TVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSS 606
Query: 86 GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQ 135
S +++S + +SSSS+SSSS + + S+
Sbjct: 607 SSSSSSTS--------------------GSSSRDSSSSTSSSSESRSRSR 636
Score = 31.2 bits (69), Expect = 4.5
Identities = 23/64 (35%), Positives = 31/64 (48%)
Query: 19 EVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASP 78
E +S T + + K K S SSSSS+SS+ S SSSSS S+S
Sbjct: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
Query: 79 STSS 82
S++S
Sbjct: 611 SSTS 614
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 41.2 bits (95), Expect = 0.004
Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%)
Query: 318 IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 362
++ ++ Q + L +E ERN + +D + + +L LSD LQ
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
Query: 363 YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 418
+ + E LEE + + E + L Q+ E + L RL++E D L+ LD
Sbjct: 1383 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1438
Query: 419 QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 477
Q+ L++ +EK+ Q+ + LL E + ++S Y R + + +
Sbjct: 1439 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1486
Query: 478 EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 537
+A + E ++T + +D V D+ KN + K A ET + +
Sbjct: 1487 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1544
Query: 538 PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 593
+ EL + D+KLR N +A + E+ L +D ++ L
Sbjct: 1545 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1594
Query: 594 AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 646
++L ++ D K + AA KLEG KD+EL D I+ ++
Sbjct: 1595 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Score = 32.0 bits (71), Expect = 2.6
Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%)
Query: 337 ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 393
ER++ E + L+ L S L ++ +++ ET AE ++ +++E+
Sbjct: 866 ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921
Query: 394 EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 451
E LH + RLEEE DR ++ + +E+QL E A QK L + E +
Sbjct: 922 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 979
Query: 452 IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 508
I+ L L+ + + LL++ I S + N +++ + L K+K
Sbjct: 980 IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1032
Query: 509 DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 562
+ +I ++ K EK + +K E + + A+L A+ + K++ KE
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1089
Query: 563 EELEKMLDKI 572
EEL+ L ++
Sbjct: 1090 EELQAALARL 1099
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 41.2 bits (95), Expect = 0.004
Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%)
Query: 318 IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 362
++ ++ Q + L +E ERN + +D + + +L LSD LQ
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Query: 363 YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 418
+ + E LEE + + E + L Q+ E + L RL++E D L+ LD
Sbjct: 1390 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1445
Query: 419 QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 477
Q+ L++ +EK+ Q+ + LL E + ++S Y R + + +
Sbjct: 1446 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1493
Query: 478 EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 537
+A + E ++T + +D V D+ KN + K A ET + +
Sbjct: 1494 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1551
Query: 538 PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 593
+ EL + D+KLR N +A + E+ L +D ++ L
Sbjct: 1552 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1601
Query: 594 AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 646
++L ++ D K + AA KLEG KD+EL D I+ ++
Sbjct: 1602 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1648
Score = 32.0 bits (71), Expect = 2.6
Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%)
Query: 337 ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 393
ER++ E + L+ L S L ++ +++ ET AE ++ +++E+
Sbjct: 873 ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 928
Query: 394 EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 451
E LH + RLEEE DR ++ + +E+QL E A QK L + E +
Sbjct: 929 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 986
Query: 452 IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 508
I+ L L+ + + LL++ I S + N +++ + L K+K
Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1039
Query: 509 DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 562
+ +I ++ K EK + +K E + + A+L A+ + K++ KE
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1096
Query: 563 EELEKMLDKI 572
EEL+ L ++
Sbjct: 1097 EELQAALARL 1106
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 41.2 bits (95), Expect = 0.004
Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%)
Query: 318 IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 362
++ ++ Q + L +E ERN + +D + + +L LSD LQ
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Query: 363 YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 418
+ + E LEE + + E + L Q+ E + L RL++E D L+ LD
Sbjct: 1390 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1445
Query: 419 QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 477
Q+ L++ +EK+ Q+ + LL E + ++S Y R + + +
Sbjct: 1446 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1493
Query: 478 EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 537
+A + E ++T + +D V D+ KN + K A ET + +
Sbjct: 1494 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1551
Query: 538 PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 593
+ EL + D+KLR N +A + E+ L +D ++ L
Sbjct: 1552 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1601
Query: 594 AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 646
++L ++ D K + AA KLEG KD+EL D I+ ++
Sbjct: 1602 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1648
Score = 32.0 bits (71), Expect = 2.6
Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%)
Query: 337 ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 393
ER++ E + L+ L S L ++ +++ ET AE ++ +++E+
Sbjct: 873 ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 928
Query: 394 EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 451
E LH + RLEEE DR ++ + +E+QL E A QK L + E +
Sbjct: 929 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 986
Query: 452 IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 508
I+ L L+ + + LL++ I S + N +++ + L K+K
Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1039
Query: 509 DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 562
+ +I ++ K EK + +K E + + A+L A+ + K++ KE
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1096
Query: 563 EELEKMLDKI 572
EEL+ L ++
Sbjct: 1097 EELQAALARL 1106
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 41.2 bits (95), Expect = 0.004
Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%)
Query: 318 IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 362
++ ++ Q + L +E ERN + +D + + +L LSD LQ
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
Query: 363 YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 418
+ + E LEE + + E + L Q+ E + L RL++E D L+ LD
Sbjct: 1383 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1438
Query: 419 QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 477
Q+ L++ +EK+ Q+ + LL E + ++S Y R + + +
Sbjct: 1439 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1486
Query: 478 EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 537
+A + E ++T + +D V D+ KN + K A ET + +
Sbjct: 1487 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1544
Query: 538 PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 593
+ EL + D+KLR N +A + E+ L +D ++ L
Sbjct: 1545 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1594
Query: 594 AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 646
++L ++ D K + AA KLEG KD+EL D I+ ++
Sbjct: 1595 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Score = 32.0 bits (71), Expect = 2.6
Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%)
Query: 337 ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 393
ER++ E + L+ L S L ++ +++ ET AE ++ +++E+
Sbjct: 866 ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921
Query: 394 EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 451
E LH + RLEEE DR ++ + +E+QL E A QK L + E +
Sbjct: 922 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 979
Query: 452 IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 508
I+ L L+ + + LL++ I S + N +++ + L K+K
Sbjct: 980 IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1032
Query: 509 DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 562
+ +I ++ K EK + +K E + + A+L A+ + K++ KE
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1089
Query: 563 EELEKMLDKI 572
EEL+ L ++
Sbjct: 1090 EELQAALARL 1099
>gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens]
Length = 1013
Score = 41.2 bits (95), Expect = 0.004
Identities = 33/92 (35%), Positives = 44/92 (47%), Gaps = 14/92 (15%)
Query: 26 GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCL 85
G + P T+ +SSSSSSS+SS+ S+SSSSS PP P S+ P
Sbjct: 72 GGAAPNPATTTAASSSSSSSSSSSSSSSSASS-SSSSSSSSPPPASPPASSPPRVLEL-P 129
Query: 86 GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMA 117
GV AA F D L F+ + A++A
Sbjct: 130 GVPAAA-----------FSDVLNFI-YSARLA 149
>gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens]
Length = 1013
Score = 41.2 bits (95), Expect = 0.004
Identities = 33/92 (35%), Positives = 44/92 (47%), Gaps = 14/92 (15%)
Query: 26 GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCL 85
G + P T+ +SSSSSSS+SS+ S+SSSSS PP P S+ P
Sbjct: 72 GGAAPNPATTTAASSSSSSSSSSSSSSSSASS-SSSSSSSSPPPASPPASSPPRVLEL-P 129
Query: 86 GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMA 117
GV AA F D L F+ + A++A
Sbjct: 130 GVPAAA-----------FSDVLNFI-YSARLA 149
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 40.8 bits (94), Expect = 0.006
Identities = 46/184 (25%), Positives = 76/184 (41%), Gaps = 25/184 (13%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
S P + + + DG + PP K++K ++ S S+SS+ R TS+ S
Sbjct: 984 SGPGLDSKPGKRSRTPSNDGKSKDKPP---KRKKADTEGKSPSHSSSNRPFTPPTSTGGS 1040
Query: 67 TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQ------------KKLRFEDTLEFVGFDA 114
P S +P GV+ + IQ ++ + +
Sbjct: 1041 KSPGSAGRSQTPP------GVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGS 1094
Query: 115 KMAEESSSSSSSSSPTAA--TSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSK 172
K SSSSSSS+ T+ S + + + S L SS+ S ++G ++S SS + K
Sbjct: 1095 KSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKN--SSQSGGK 1152
Query: 173 PGSA 176
PGS+
Sbjct: 1153 PGSS 1156
Score = 32.7 bits (73), Expect = 1.5
Identities = 44/192 (22%), Positives = 77/192 (40%), Gaps = 23/192 (11%)
Query: 4 TGFSSPSPSAAAAAQEVRSA--TDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDST 61
+G S S +++++ + S + G+ S P S+ +SSS SSS SS
Sbjct: 1229 SGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHG 1288
Query: 62 SSSSSTPPLQPRDSASPSTSSF-----------------CLGVSVAASSHVPIQKKLRFE 104
SS +P + S + +GVS +SSH P+ K
Sbjct: 1289 SSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSH-PMSSKHNMS 1347
Query: 105 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 164
EF G K ++ S S+S S + S ++ ++K++ + VA + + S +
Sbjct: 1348 GG-EFQGKREKSDKDKSKVSTSGS--SVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSI 1404
Query: 165 VSSFANSKPGSA 176
+ KPG +
Sbjct: 1405 KAKVTLQKPGES 1416
>gi|153792110 HEG homolog 1 [Homo sapiens]
Length = 1381
Score = 40.8 bits (94), Expect = 0.006
Identities = 52/163 (31%), Positives = 73/163 (44%), Gaps = 19/163 (11%)
Query: 22 SATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTS 81
S TD ++S+ S+ S+SS S SS + ++ SS + A PST
Sbjct: 570 SITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISS-----YDGEYAQPSTE 624
Query: 82 SFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSS---------PTAA 132
S L S S+ P + +T + DA+ +SSSSSSSSS P +
Sbjct: 625 SPVLHTS-NLPSYTPT---INMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLPS 680
Query: 133 TSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGS 175
SQ L + SIL S+ ASVH + +ST SS + P S
Sbjct: 681 VSQSHHLFS-SILPSTRASVHLLKSTSDASTPWSSSPSPLPVS 722
Score = 35.0 bits (79), Expect = 0.31
Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 9/128 (7%)
Query: 6 FSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSS 65
FSS PS A+ ++S +D +T + S L +S+S+ + S +T S
Sbjct: 688 FSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVS------QTTLPQS 741
Query: 66 STPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSS 125
S+ P+ PR +P TS S S + + + K+ ES S S
Sbjct: 742 SSTPVLPRARETPVTS---FQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSL 798
Query: 126 SSSPTAAT 133
S PT +T
Sbjct: 799 VSLPTEST 806
>gi|8923106 zinc finger, CCHC domain containing 10 [Homo sapiens]
Length = 170
Score = 40.4 bits (93), Expect = 0.007
Identities = 26/84 (30%), Positives = 44/84 (52%)
Query: 17 AQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSA 76
++ V S++ ++ ++ S+ + + S+SSSS +S + S+SS+SST DS
Sbjct: 83 SKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTSSSSSDSD 142
Query: 77 SPSTSSFCLGVSVAASSHVPIQKK 100
S S+SS S +SS KK
Sbjct: 143 SDSSSSSSSSTSTDSSSDDEPPKK 166
Score = 38.1 bits (87), Expect = 0.037
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 19/117 (16%)
Query: 26 GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCL 85
G T+ K+ K +SSSSSS+ S+ + + +S++ + D+ S+SS
Sbjct: 70 GETNVERKAKKKRSKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSS 129
Query: 86 GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNK 142
S +SS + +SSSSSSSS+ T ++S + K K
Sbjct: 130 ASSTTSSS-------------------SSDSDSDSSSSSSSSTSTDSSSDDEPPKKK 167
Score = 37.7 bits (86), Expect = 0.048
Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 8/79 (10%)
Query: 4 TGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSS 63
T SS S ++A+ S +S++ + + +SSSS+SS +S+ D DS SS
Sbjct: 87 TSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTSSSSSDSDSDSS 146
Query: 64 SSSTPPLQPRDSASPSTSS 82
SSS S+S ST S
Sbjct: 147 SSS--------SSSTSTDS 157
Score = 35.4 bits (80), Expect = 0.24
Identities = 19/72 (26%), Positives = 40/72 (55%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS S ++ ++++ ++T ++ + + +S+SS++S+SS++ + S+SSSSS
Sbjct: 93 SSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTSSSSSDSDSDSSSSSSSS 152
Query: 67 TPPLQPRDSASP 78
T D P
Sbjct: 153 TSTDSSSDDEPP 164
Score = 34.3 bits (77), Expect = 0.53
Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Query: 8 SPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSST 67
S S ++++++ SA+D ++ + +++ + + + SSS+SS+ S+SSS S
Sbjct: 83 SKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASSTTSSSSSDS- 141
Query: 68 PPLQPRDSASPSTSSFCLGVSVAASSHVPIQKK 100
DS S S+SS ++ P +KK
Sbjct: 142 ------DSDSSSSSSSSTSTDSSSDDEPPKKKK 168
Score = 33.9 bits (76), Expect = 0.69
Identities = 44/149 (29%), Positives = 63/149 (42%), Gaps = 52/149 (34%)
Query: 30 TTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSV 89
T AKK++ S +SSSS+SS DS++S SS+ +S STSS
Sbjct: 72 TNVERKAKKKRSKSVTSSSSSSS------DSSASDSSS------ESEETSTSS------- 112
Query: 90 AASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSV 149
SS D+ E SSSSSSS+S T ++ SS
Sbjct: 113 --SSE------------------DSDTDESSSSSSSSASSTTSS-------------SSS 139
Query: 150 ASVHHANGLAKSSTTVSSFANSKPGSAKK 178
S ++ + SST+ S ++ +P KK
Sbjct: 140 DSDSDSSSSSSSSTSTDSSSDDEPPKKKK 168
Score = 31.2 bits (69), Expect = 4.5
Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 7 SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 66
SS S + ++ S TD ++S++ S+ SSSSS S+S + STS+ SS
Sbjct: 102 SSESEETSTSSSSEDSDTDESSSSS---SSSASSTTSSSSSDSDSDSSSSSSSSTSTDSS 158
Query: 67 TPPLQPR 73
+ P+
Sbjct: 159 SDDEPPK 165
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 40.0 bits (92), Expect = 0.010
Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 19/160 (11%)
Query: 3 PTGFSSPSPSAA-----AAAQEVR---SATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNE 54
P +P P AA A +E + ++ G PP + +++ S S +
Sbjct: 239 PKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAK 298
Query: 55 REDFDSTSSSSSTPPLQPRDSASPSTS--------SFCLGVSVAASSHVPIQKK---LRF 103
++ S+ S S P PR S+S S S S G V A S KK +
Sbjct: 299 KQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEE 358
Query: 104 EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKS 143
++ + F ++ A+ S S+SSSSS +++ S + +N S
Sbjct: 359 SNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHS 398
Score = 35.0 bits (79), Expect = 0.31
Identities = 34/123 (27%), Positives = 52/123 (42%), Gaps = 18/123 (14%)
Query: 11 PSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSS---SST 67
P A A EV + + ++ SA+ NSSSSS S+S ++ E + S S
Sbjct: 347 PREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMV 406
Query: 68 PPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSS 127
LQ +S +SS G A ++ +L F D+ ES +S+ SS
Sbjct: 407 EDLQSEESDEDDSSS---GEEAAGKTNPGRDSRLSFSDS------------ESDNSADSS 451
Query: 128 SPT 130
P+
Sbjct: 452 LPS 454
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,333,166
Number of Sequences: 37866
Number of extensions: 1294543
Number of successful extensions: 12768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 279
Number of HSP's that attempted gapping in prelim test: 9095
Number of HSP's gapped (non-prelim): 2495
length of query: 895
length of database: 18,247,518
effective HSP length: 111
effective length of query: 784
effective length of database: 14,044,392
effective search space: 11010803328
effective search space used: 11010803328
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.